ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0942 check: MH T KOG0592 Signal transduction mechanisms 3-phosphoinositide-dependent protein kinase (PDK1)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0942 325707 323767 -647
(647 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 487 e-137
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 234 4e-61
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 232 1e-60
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 224 2e-58
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 217 4e-56
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 206 9e-53
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 201 4e-51
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 195 2e-49
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 185 2e-46
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 184 3e-46
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 172 1e-42
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 169 9e-42
CE24761 [D] KOG0580 Serine/threonine protein kinase 168 2e-41
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 163 7e-40
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 161 3e-39
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 161 3e-39
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 159 1e-38
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 158 2e-38
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 157 4e-38
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 157 5e-38
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 157 5e-38
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 157 6e-38
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 156 8e-38
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 155 1e-37
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 155 1e-37
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 155 1e-37
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 154 4e-37
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 154 5e-37
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 153 7e-37
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 153 7e-37
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 153 9e-37
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 151 3e-36
YPL209c [D] KOG0580 Serine/threonine protein kinase 151 3e-36
CE29092 [T] KOG0694 Serine/threonine protein kinase 150 4e-36
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 150 6e-36
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 150 6e-36
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 150 6e-36
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 150 8e-36
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 149 1e-35
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 149 2e-35
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 148 3e-35
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 148 3e-35
At2g45490 [D] KOG0580 Serine/threonine protein kinase 148 3e-35
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 147 4e-35
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 147 4e-35
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 147 4e-35
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 147 6e-35
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 146 8e-35
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 145 1e-34
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 145 1e-34
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 145 2e-34
7301734 [T] KOG0694 Serine/threonine protein kinase 145 2e-34
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 144 4e-34
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 144 5e-34
At4g18700 [T] KOG0583 Serine/threonine protein kinase 144 5e-34
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 143 9e-34
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 142 1e-33
CE17354 [T] KOG0694 Serine/threonine protein kinase 142 1e-33
CE17353 [T] KOG0694 Serine/threonine protein kinase 142 1e-33
7299536 [D] KOG0580 Serine/threonine protein kinase 142 1e-33
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 142 2e-33
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 142 2e-33
At2g25880 [D] KOG0580 Serine/threonine protein kinase 141 3e-33
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 141 4e-33
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 141 4e-33
CE15612 [T] KOG0690 Serine/threonine protein kinase 141 4e-33
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 141 4e-33
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 140 5e-33
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 140 6e-33
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 140 8e-33
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 140 8e-33
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 139 1e-32
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 139 1e-32
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 139 1e-32
At4g32830 [D] KOG0580 Serine/threonine protein kinase 139 1e-32
At1g29230 [T] KOG0583 Serine/threonine protein kinase 139 1e-32
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 139 2e-32
At5g45810 [T] KOG0583 Serine/threonine protein kinase 138 3e-32
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 137 4e-32
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 137 5e-32
At2g30360 [T] KOG0583 Serine/threonine protein kinase 137 7e-32
7295638 [T] KOG0603 Ribosomal protein S6 kinase 137 7e-32
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 136 1e-31
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 136 1e-31
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 136 1e-31
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 135 1e-31
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 135 1e-31
CE03979 [T] KOG0614 cGMP-dependent protein kinase 135 1e-31
7302861 [T] KOG0696 Serine/threonine protein kinase 135 1e-31
7300106 [T] KOG0690 Serine/threonine protein kinase 135 1e-31
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 135 1e-31
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 135 1e-31
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 135 2e-31
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 135 2e-31
At5g39440 [T] KOG0583 Serine/threonine protein kinase 135 2e-31
CE02586 [T] KOG0696 Serine/threonine protein kinase 135 3e-31
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 134 4e-31
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 134 4e-31
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 134 4e-31
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 134 4e-31
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 134 4e-31
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 134 4e-31
At4g14580 [T] KOG0583 Serine/threonine protein kinase 134 4e-31
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 134 6e-31
CE05274 [T] KOG0690 Serine/threonine protein kinase 134 6e-31
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 133 1e-30
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 133 1e-30
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 133 1e-30
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 133 1e-30
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 133 1e-30
At3g01090 [T] KOG0583 Serine/threonine protein kinase 133 1e-30
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 132 1e-30
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 132 1e-30
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 132 1e-30
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 132 2e-30
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 132 2e-30
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 132 2e-30
CE19898 [T] KOG0614 cGMP-dependent protein kinase 132 2e-30
CE19897 [T] KOG0614 cGMP-dependent protein kinase 132 2e-30
At3g29160 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 131 4e-30
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 131 4e-30
At4g30960 [T] KOG0583 Serine/threonine protein kinase 131 4e-30
At2g25090 [T] KOG0583 Serine/threonine protein kinase 131 4e-30
7297611 [T] KOG0614 cGMP-dependent protein kinase 131 4e-30
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 130 8e-30
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 130 8e-30
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 130 8e-30
7302860 [T] KOG0696 Serine/threonine protein kinase 130 8e-30
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 129 1e-29
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 129 1e-29
At2g34180 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 129 1e-29
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 129 1e-29
At5g25110 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
7293735 [R] KOG0605 NDR and related serine/threonine kinases 129 1e-29
At1g30270 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 128 2e-29
CE29298 [T] KOG0690 Serine/threonine protein kinase 128 2e-29
CE18646 [T] KOG0690 Serine/threonine protein kinase 128 2e-29
At5g10930 [T] KOG0583 Serine/threonine protein kinase 128 2e-29
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 128 3e-29
7296166 [T] KOG0614 cGMP-dependent protein kinase 128 3e-29
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 128 3e-29
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 127 4e-29
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 127 4e-29
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 127 4e-29
7299437 [R] KOG0586 Serine/threonine protein kinase 127 4e-29
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 127 5e-29
7297776 [D] KOG0580 Serine/threonine protein kinase 127 5e-29
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 127 7e-29
CE21025 [D] KOG0580 Serine/threonine protein kinase 127 7e-29
At4g24400 [T] KOG0583 Serine/threonine protein kinase 127 7e-29
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 7e-29
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 7e-29
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 126 9e-29
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 126 9e-29
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 126 1e-28
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 125 2e-28
At5g01810 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
7294770 [T] KOG0603 Ribosomal protein S6 kinase 125 2e-28
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 125 2e-28
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 125 2e-28
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 125 2e-28
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 125 3e-28
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 125 3e-28
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 3e-28
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 125 3e-28
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 125 3e-28
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 124 3e-28
At2g26980 [T] KOG0583 Serine/threonine protein kinase 124 3e-28
At2g38490 [T] KOG0583 Serine/threonine protein kinase 124 4e-28
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 124 4e-28
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 124 6e-28
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 124 6e-28
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 124 6e-28
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 124 6e-28
CE02604 [T] KOG0695 Serine/threonine protein kinase 124 6e-28
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 6e-28
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 6e-28
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 8e-28
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 123 1e-27
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 123 1e-27
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 123 1e-27
YBL105c [T] KOG0694 Serine/threonine protein kinase 122 1e-27
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 122 1e-27
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 122 1e-27
At5g45820 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 122 2e-27
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 122 2e-27
CE27768 [R] KOG0586 Serine/threonine protein kinase 122 2e-27
CE23838 [R] KOG0586 Serine/threonine protein kinase 122 2e-27
At5g35410 [T] KOG0583 Serine/threonine protein kinase 122 2e-27
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 122 2e-27
7303915 [T] KOG0694 Serine/threonine protein kinase 122 2e-27
7303914 [T] KOG0694 Serine/threonine protein kinase 122 2e-27
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 122 2e-27
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 121 3e-27
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 121 3e-27
7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 121 3e-27
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 121 4e-27
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 121 4e-27
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 121 4e-27
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 121 4e-27
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 121 4e-27
7299438 [R] KOG0586 Serine/threonine protein kinase 121 4e-27
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 120 5e-27
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 120 5e-27
CE28218 [D] KOG0588 Serine/threonine protein kinase 120 5e-27
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 120 5e-27
At1g01140 [T] KOG0583 Serine/threonine protein kinase 120 5e-27
CE00847 [T] KOG0583 Serine/threonine protein kinase 120 6e-27
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 120 8e-27
At5g58380 [T] KOG0583 Serine/threonine protein kinase 120 8e-27
At5g01820 [T] KOG0583 Serine/threonine protein kinase 120 8e-27
At1g48260 [T] KOG0583 Serine/threonine protein kinase 120 8e-27
7290249 [R] KOG0586 Serine/threonine protein kinase 120 8e-27
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 119 1e-26
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 119 1e-26
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 1e-26
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 119 1e-26
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 119 1e-26
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 119 1e-26
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 119 1e-26
At5g57630 [T] KOG0583 Serine/threonine protein kinase 119 1e-26
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 119 1e-26
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 119 2e-26
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
7302570 [R] KOG0586 Serine/threonine protein kinase 119 2e-26
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 119 2e-26
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 118 2e-26
CE28643 [T] KOG0583 Serine/threonine protein kinase 118 2e-26
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 118 2e-26
CE18699 [T] KOG0694 Serine/threonine protein kinase 118 2e-26
CE07458 [T] KOG0583 Serine/threonine protein kinase 118 2e-26
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 2e-26
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 118 3e-26
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 118 3e-26
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 118 3e-26
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 118 3e-26
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 118 3e-26
7299793 [T] KOG0583 Serine/threonine protein kinase 118 3e-26
YDR477w [T] KOG0583 Serine/threonine protein kinase 117 4e-26
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 117 4e-26
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 117 4e-26
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 117 4e-26
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 117 4e-26
At4g33950 [T] KOG0583 Serine/threonine protein kinase 117 4e-26
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 117 5e-26
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 5e-26
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 5e-26
At3g23000 [T] KOG0583 Serine/threonine protein kinase 117 5e-26
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 117 5e-26
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 117 7e-26
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 7e-26
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 116 9e-26
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 116 9e-26
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 116 9e-26
CE18454 [T] KOG4717 Serine/threonine protein kinase 116 9e-26
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 116 9e-26
At2g23030 [T] KOG0583 Serine/threonine protein kinase 116 9e-26
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 9e-26
7302464 [R] KOG0586 Serine/threonine protein kinase 116 9e-26
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 9e-26
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 116 1e-25
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 116 1e-25
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 116 1e-25
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 116 1e-25
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 116 1e-25
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 116 1e-25
YDR507c [D] KOG0588 Serine/threonine protein kinase 115 2e-25
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 115 2e-25
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 115 2e-25
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 115 2e-25
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 115 2e-25
At5g39420 [D] KOG0600 Cdc2-related protein kinase 115 2e-25
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 115 2e-25
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 115 3e-25
7303211 [T] KOG4717 Serine/threonine protein kinase 115 3e-25
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 114 4e-25
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 114 4e-25
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 114 4e-25
7303111 [T] KOG0695 Serine/threonine protein kinase 114 4e-25
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 114 5e-25
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 114 5e-25
CE17284 [T] KOG0583 Serine/threonine protein kinase 114 5e-25
At3g50500 [T] KOG0583 Serine/threonine protein kinase 114 5e-25
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 114 5e-25
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 114 5e-25
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 114 6e-25
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 6e-25
7290150 [T] KOG0583 Serine/threonine protein kinase 114 6e-25
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 113 8e-25
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 113 8e-25
At5g66880 [T] KOG0583 Serine/threonine protein kinase 113 8e-25
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 113 8e-25
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 113 1e-24
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 113 1e-24
At5g07070 [T] KOG0583 Serine/threonine protein kinase 113 1e-24
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 113 1e-24
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 1e-24
At1g71530 [D] KOG0600 Cdc2-related protein kinase 113 1e-24
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 112 1e-24
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 1e-24
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 112 2e-24
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 112 2e-24
At4g40010 [T] KOG0583 Serine/threonine protein kinase 112 2e-24
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 112 2e-24
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 112 2e-24
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 112 2e-24
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 112 2e-24
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
7294217 [D] KOG0588 Serine/threonine protein kinase 112 2e-24
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 111 3e-24
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 3e-24
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 111 3e-24
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 111 3e-24
At5g50860 [D] KOG0600 Cdc2-related protein kinase 111 3e-24
At3g17510 [T] KOG0583 Serine/threonine protein kinase 111 4e-24
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 4e-24
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 111 4e-24
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 110 5e-24
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 110 5e-24
CE28479 [T] KOG0583 Serine/threonine protein kinase 110 5e-24
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 110 5e-24
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 110 7e-24
At1g74330 [D] KOG0600 Cdc2-related protein kinase 110 7e-24
YKL101w [D] KOG0588 Serine/threonine protein kinase 110 9e-24
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 110 9e-24
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 110 9e-24
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 110 9e-24
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 109 1e-23
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 109 1e-23
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 109 1e-23
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 109 1e-23
At4g10010 [D] KOG0600 Cdc2-related protein kinase 109 1e-23
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 109 1e-23
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
At1g78290 [T] KOG0583 Serine/threonine protein kinase 108 2e-23
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 108 2e-23
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 108 3e-23
CE29020 [T] KOG0660 Mitogen-activated protein kinase 108 3e-23
CE02074 [T] KOG0986 G protein-coupled receptor kinase 108 3e-23
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 108 3e-23
At1g54610 [D] KOG0600 Cdc2-related protein kinase 108 3e-23
At1g09600 [D] KOG0600 Cdc2-related protein kinase 108 3e-23
YDR122w [T] KOG0583 Serine/threonine protein kinase 108 3e-23
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 108 3e-23
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 108 3e-23
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 108 3e-23
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 4e-23
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 107 4e-23
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 107 6e-23
YCL024w [T] KOG0583 Serine/threonine protein kinase 107 6e-23
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 107 6e-23
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 107 6e-23
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 107 6e-23
At5g08590 [T] KOG0583 Serine/threonine protein kinase 107 6e-23
At1g18670 [D] KOG0600 Cdc2-related protein kinase 107 6e-23
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 107 6e-23
7291043 [T] KOG0660 Mitogen-activated protein kinase 107 6e-23
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 107 6e-23
YLR096w [T] KOG0583 Serine/threonine protein kinase 107 7e-23
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 107 7e-23
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 7e-23
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 107 7e-23
At1g33770 [D] KOG0600 Cdc2-related protein kinase 107 7e-23
At1g03740 [D] KOG0600 Cdc2-related protein kinase 107 7e-23
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 106 1e-22
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 106 1e-22
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 106 1e-22
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 106 1e-22
At4g22940 [D] KOG0600 Cdc2-related protein kinase 106 1e-22
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 1e-22
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 1e-22
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 105 2e-22
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 2e-22
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
CE28674 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
CE07510 [T] KOG0201 Serine/threonine protein kinase 105 2e-22
At1g53050 [D] KOG0600 Cdc2-related protein kinase 105 2e-22
YPL141c [T] KOG0583 Serine/threonine protein kinase 105 2e-22
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 2e-22
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 105 2e-22
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 2e-22
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 105 2e-22
7297080 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 105 3e-22
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 105 3e-22
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 3e-22
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 3e-22
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 104 4e-22
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 104 4e-22
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 104 4e-22
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 4e-22
7300224 [T] KOG0201 Serine/threonine protein kinase 104 4e-22
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 104 5e-22
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 104 5e-22
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 104 5e-22
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 104 5e-22
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 104 5e-22
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 104 5e-22
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 103 6e-22
CE16081 [T] KOG0583 Serine/threonine protein kinase 103 6e-22
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 103 6e-22
At3g05050 [D] KOG0600 Cdc2-related protein kinase 103 6e-22
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 6e-22
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 103 8e-22
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 103 8e-22
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 103 8e-22
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 103 8e-22
YPL150w [T] KOG0583 Serine/threonine protein kinase 103 1e-21
YOR233w [T] KOG0583 Serine/threonine protein kinase 103 1e-21
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 103 1e-21
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 103 1e-21
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 103 1e-21
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 103 1e-21
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 103 1e-21
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 103 1e-21
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 103 1e-21
At5g44290 [D] KOG0600 Cdc2-related protein kinase 103 1e-21
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 103 1e-21
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 102 1e-21
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 102 1e-21
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 102 1e-21
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 102 1e-21
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 102 1e-21
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 102 1e-21
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 2e-21
7296451 [D] KOG0600 Cdc2-related protein kinase 102 2e-21
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 102 2e-21
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 102 2e-21
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 102 2e-21
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 2e-21
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 102 2e-21
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 102 2e-21
At5g63650 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 101 3e-21
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 101 3e-21
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 3e-21
YKL139w [D] KOG0600 Cdc2-related protein kinase 101 4e-21
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 101 4e-21
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 4e-21
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 101 4e-21
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 4e-21
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 4e-21
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 101 4e-21
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 101 4e-21
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 100 5e-21
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 5e-21
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 5e-21
At3g15220 [T] KOG0201 Serine/threonine protein kinase 100 5e-21
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 7e-21
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 100 7e-21
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 7e-21
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 100 7e-21
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 7e-21
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 100 7e-21
At1g10940 [T] KOG0583 Serine/threonine protein kinase 100 7e-21
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 100 9e-21
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 100 9e-21
CE29300 [T] KOG0694 Serine/threonine protein kinase 100 9e-21
CE29299 [T] KOG0694 Serine/threonine protein kinase 100 9e-21
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 100 9e-21
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 9e-21
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 100 1e-20
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 99 2e-20
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 99 2e-20
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 99 2e-20
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 99 2e-20
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 99 2e-20
CE01554 [T] KOG0986 G protein-coupled receptor kinase 99 2e-20
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
At1g57700 [D] KOG0600 Cdc2-related protein kinase 99 2e-20
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 99 2e-20
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 99 2e-20
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 99 2e-20
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
CE27131_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 99 3e-20
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 3e-20
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 99 3e-20
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 98 3e-20
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 98 3e-20
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 98 3e-20
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 487 bits (1253), Expect = e-137
Identities = 297/721 (41%), Positives = 399/721 (55%), Gaps = 99/721 (13%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVYKAVDR-STGQLFAIKVCSKKHIISENKVKYVTIEKN 60
SRKR+P DF FKE LGHGSYSTV+KA+D+ S +++AIKVCSKKHII E KVKYVTIEKN
Sbjct: 3 SRKRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKN 62
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
T+NLLA +H GIIKLYYTFHD ENLYFVLDFAP FN+ WT+HF QL
Sbjct: 63 TMNLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQL 122
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNL----------------AAT 164
IDALE+IH ++HRDLKPEN+LL +G+LMITDFG A+ + +
Sbjct: 123 IDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSK 182
Query: 165 DNLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEK 224
DN + +SFVGTAEYVSPELLL N+ + SDIWA+GCM+YQF QG PPFRGENEL FEK
Sbjct: 183 DN-QNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEK 241
Query: 225 IVNLDYHW---------IYMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNK 275
IV LDY W ++ + +LV KILV++ + R +L QIK H +F +DW +K
Sbjct: 242 IVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFSKVDWNDK 301
Query: 276 ELIWKGIWQLFGNRNHN------NFNGPSMMNKQLHVIDTTIKNIPIQPRKR-KPMKVTQ 328
IW+GIWQ G N + +QLHVIDT ++I I +KR KP K++
Sbjct: 302 IKIWRGIWQSQGQSLQQTTLGLPNIPQNILPTRQLHVIDTPARSIQITKQKRKKPTKISN 361
Query: 329 TTSSIVEWRKTLGLSPVSGSVG--PNGLP-------KQMKSHVPSRST------PNSPSR 373
TTSSIV WRK LG+S +G P+ P + ++ + ST PNS S
Sbjct: 362 TTSSIVVWRKRLGISTGKDDLGTVPSTTPAVTAPNDTNVLTNTAAHSTANIALPPNSQSN 421
Query: 374 ALTGKGYTKAMPNTAPPLETCKTPMM-------PVSPLYITTPGASASFSPKKFNNASDS 426
+ K PN PP K P++ + P S P+K + +S S
Sbjct: 422 QV--KRAQLVAPNRIPP----KVPVINDNVRNKSIPRTKPNVPPLQTSSIPQKLSTSSAS 475
Query: 427 NRLLTPPASPK-----------------ALKQGWVKILEIPYVSSSKKTFSSTEYSFIDD 469
+ L P + LKQ +V I IPY S Y+ ID+
Sbjct: 476 SALSAPSTEIRNQDLTHTLDGRNSIDIHVLKQDYVFIYGIPY-EHEGPAMSLNSYNKIDN 534
Query: 470 RLITRFITEQKSQIINS-SMLSLLTLEPNGQFSY--------TPKGDSTRQMISIVDQNL 520
LIT + + K ++ NS S L +LTL+ +G SY + + QM +I D +L
Sbjct: 535 DLITSLVAQHKEELKNSESFLQVLTLKKSGMLSYKNTVMEGNDDQENKEHQMANIEDTDL 594
Query: 521 SIYDLEFNETKNSGYLIFEKFKSKVWLIALPK---------SAPSDFVINSRQKWVDSLF 571
S+YD EFNE G+LI EK+K+++W I+LP +A IN+ + WVD F
Sbjct: 595 SMYDFEFNELTRKGFLILEKYKNRIWFISLPSYSTLSKIPFNAVKSSTINNNENWVDCFF 654
Query: 572 KTKAALESEKLTKKVDNLSLKPPETCSTSSKPRKSPQDN-MFVSSSRAEVLYTLNKQKRS 630
+ + LE +++ K+ N+S + SS P S ++ + + ++ + YT ++
Sbjct: 655 RARQLLEEKQILDKISNVSFDSKASSEPSSPPPISRKERPLSIGNNVTTLSYTAKNGSQN 714
Query: 631 N 631
N
Sbjct: 715 N 715
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 234 bits (596), Expect = 4e-61
Identities = 118/278 (42%), Positives = 169/278 (60%), Gaps = 9/278 (3%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
RK+ P+DF F + LG GS+STV A + +T + +AIK+ K+HII ENKV YVT E++ +
Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ L +HP +KLY+TF D E LYF L +A F+E T+ + +++
Sbjct: 135 SRL---DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVS 191
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
ALEY+HG ++HRDLKPEN+LL+ + + ITDFG A L+ + +SFVGTA+YVSP
Sbjct: 192 ALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSP 251
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
ELL + + SD+WA+GC++YQ G PPFR NE F+KI+ L+Y + D
Sbjct: 252 ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARD 311
Query: 243 LVSKILVLDPDSRYTLPQ------IKNHAWFQGIDWTN 274
LV K+LVLD R + +K H +F+ + W N
Sbjct: 312 LVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWEN 349
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 232 bits (592), Expect = 1e-60
Identities = 131/313 (41%), Positives = 177/313 (55%), Gaps = 27/313 (8%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF F E LG GSYSTV A + ST + +AIKV K+HII E K KYV IEK L +L+
Sbjct: 98 DFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILS-- 155
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HPG IKL+YTF D+ NLYFVL A RFNE +++ ++D+++Y+H
Sbjct: 156 KHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMH 215
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNL------------SSTSSFVGT 176
G V+HRDLKPEN+LL + ITDFG A L ++ + + SFVGT
Sbjct: 216 GRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGT 275
Query: 177 AEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMV 236
A YVSPE+L + SDIWA GC+L+Q G PPF NE F+ I++L Y +
Sbjct: 276 ARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDI 335
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKELIWKGIWQL-------FGNR 289
S +DL+ K+LVLDP R T+ +I H +F GI + N +W+L FG+
Sbjct: 336 SDVASDLIKKLLVLDPKDRLTVDEIHQHPFFNGIKFDNT------LWELPPPRLKPFGHT 389
Query: 290 NHNNFNGPSMMNK 302
+ + + P+ NK
Sbjct: 390 SVLSLSVPNASNK 402
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 224 bits (572), Expect = 2e-58
Identities = 116/276 (42%), Positives = 166/276 (60%), Gaps = 13/276 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF F E+LG GSYS+V A R +G+ +A+KV SK+++I + KVKYVT+EK L L
Sbjct: 123 KDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKL-- 180
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
GI KL++TF D +LYF+L++AP NE +++ Q+IDA++ +
Sbjct: 181 NGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSL 240
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAAT-----------DNLSSTSSFVGT 176
H ++HRD+KPEN+LL K+ +TDFG A L D + + SFVGT
Sbjct: 241 HNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGT 300
Query: 177 AEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMV 236
AEYVSPELL N ++ DIWA GC+LYQ G PPF+ NE F+K++ + Y +
Sbjct: 301 AEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGF 360
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDW 272
Q + DLV K+LV DP+ R T+ QIK H +F +++
Sbjct: 361 PQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNF 396
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 217 bits (553), Expect = 4e-56
Identities = 113/278 (40%), Positives = 168/278 (59%), Gaps = 11/278 (3%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K+ +DF F +G G+YSTV A T + +A KV +K+++I + KVKYV+IEK L
Sbjct: 173 KKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQ 232
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
L N P +++L+ TF D +LYF+L++AP +E +++ Q+IDA
Sbjct: 233 KL--NNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDA 290
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSS---------TSSFV 174
++Y+H ++HRD+KPEN+LL E K+ +TDFG A L T+N S + SFV
Sbjct: 291 IDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFV 350
Query: 175 GTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY 234
GTAEYVSPELL + +++ DIWA GC+L+Q G PPF+ NE F+K++ + Y +
Sbjct: 351 GTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTP 410
Query: 235 MVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDW 272
I DLV KILV + D R T+ QIK H +F+ +++
Sbjct: 411 GFPLIIRDLVKKILVKNLDRRLTISQIKEHHFFKDLNF 448
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 206 bits (524), Expect = 9e-53
Identities = 107/275 (38%), Positives = 160/275 (57%), Gaps = 7/275 (2%)
Query: 5 RTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNL 64
++P D+ F + +G GS+S V +A D+ + + +AIKV KK+I+ ENKVKYV IE++++
Sbjct: 49 KSPADYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMR 108
Query: 65 LAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDAL 124
L PGI +L++TF D LY+VL+ AP +E + + +++ ++
Sbjct: 109 L--NGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSI 166
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLA-----ATDNLSSTSSFVGTAEY 179
EY+H C ++HRDLKPEN+L + ITDFG A L + D + SSFVGTAEY
Sbjct: 167 EYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEY 226
Query: 180 VSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQH 239
V+PELL + + SD+WA C++YQ G+PPF G N F+KI++L+Y ++
Sbjct: 227 VAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPKLLPPD 286
Query: 240 ITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTN 274
I L S + + P R T QIK +F I W N
Sbjct: 287 IVPLFSHLFRIQPSDRSTTQQIKQFPFFATITWDN 321
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 201 bits (510), Expect = 4e-51
Identities = 109/284 (38%), Positives = 159/284 (55%), Gaps = 20/284 (7%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T DF F + G GSYS V +A + TG ++A+K+ KK I ENK YV +E+ L+ L
Sbjct: 37 TSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQL 96
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
HPGIIKLY+TF D+ +LY L+ R +E + + +++DALE
Sbjct: 97 ---EHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALE 153
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNL----------AATDNLSSTSSFVG 175
YIH ++HRD+KPENLLL+S+G + I DFG + AA+D+ + T FVG
Sbjct: 154 YIHSMGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACT--FVG 211
Query: 176 TAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYM 235
TA YV PE+L + + F +D+WA+GC LYQ GT PF+ +E F++I+ D +
Sbjct: 212 TAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNH 271
Query: 236 VSQHITDLVSKILVLDPDSR-----YTLPQIKNHAWFQGIDWTN 274
S+ DL+ ++L +P R +K H +F G+DW N
Sbjct: 272 FSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKN 315
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 195 bits (495), Expect = 2e-49
Identities = 105/284 (36%), Positives = 158/284 (54%), Gaps = 20/284 (7%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T DF + G GSYS V +A + G ++A+K+ KK I ENK YV +E+ L+ L
Sbjct: 38 TYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQL 97
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
HPGI+KL++TF D+++LY L+ R +E + + +++DALE
Sbjct: 98 ---EHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALE 154
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNL----------AATDNLSSTSSFVG 175
YIH ++HRD+KPENLLL+ +G + I DFG + AA+D+ + T FVG
Sbjct: 155 YIHNMGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACT--FVG 212
Query: 176 TAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYM 235
TA YV PE+L + + F +D+WA+GC LYQ GT PF+ +E F++I+ D +
Sbjct: 213 TAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNH 272
Query: 236 VSQHITDLVSKILVLDPDSR-----YTLPQIKNHAWFQGIDWTN 274
S+ DL+ ++L DP R +K H +F+G+DW N
Sbjct: 273 FSEAARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKN 316
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 185 bits (470), Expect = 2e-46
Identities = 98/307 (31%), Positives = 161/307 (51%), Gaps = 36/307 (11%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
KRT DF F + +G G+YS V++ + +T +FA+KV K ++ K+ + EKN L
Sbjct: 63 KRTSNDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILT 122
Query: 64 LLAH--GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
L+ G HP + +LY FHD +YFV+ F+ +K F +++
Sbjct: 123 YLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEIL 182
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA---------------SNLAAT-- 164
L+++H K+VHRD+KP+N+L+ +G ++ITDFG A +N A++
Sbjct: 183 TGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRS 242
Query: 165 -----------------DNLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFT 207
+N + ++FVGTA YVSPE+L +DIW +GC+L+Q
Sbjct: 243 SDSGSPPPTRFYSDEEEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCL 302
Query: 208 QGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWF 267
G PPFR N+ ++I LD+ + + +++++KILV DP +R T ++ H +F
Sbjct: 303 AGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRITSQELMAHKFF 362
Query: 268 QGIDWTN 274
+ +DW N
Sbjct: 363 ENVDWVN 369
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 184 bits (468), Expect = 3e-46
Identities = 98/309 (31%), Positives = 161/309 (51%), Gaps = 38/309 (12%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
KRT DF F + +G G+YS V++ + +T +FA+KV K ++ K+ + EKN L
Sbjct: 63 KRTSNDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILT 122
Query: 64 LLAH--GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
L+ G HP + +LY FHD +YFV+ F+ +K F +++
Sbjct: 123 YLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEIL 182
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA---------------SNLAAT-- 164
L+++H K+VHRD+KP+N+L+ +G ++ITDFG A +N A++
Sbjct: 183 TGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRS 242
Query: 165 -------------------DNLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQ 205
+N + ++FVGTA YVSPE+L +DIW +GC+L+Q
Sbjct: 243 SDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQ 302
Query: 206 FTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSRYTLPQIKNHA 265
G PPFR N+ ++I LD+ + + +++++KILV DP +R T ++ H
Sbjct: 303 CLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRITSQELMAHK 362
Query: 266 WFQGIDWTN 274
+F+ +DW N
Sbjct: 363 FFENVDWVN 371
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 172 bits (437), Expect = 1e-42
Identities = 101/288 (35%), Positives = 159/288 (55%), Gaps = 20/288 (6%)
Query: 9 DFSFKERLGHGSYSTVY----KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNL 64
D+S ++ +G GS+STVY K A+K+C K+ I+ V Y+ EK L L
Sbjct: 25 DYSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALAL 84
Query: 65 LAHGN--HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXX--XRFNEAWTKHFMCQL 120
++ HPGI+ LY TF DSE+LYFVL++A +FN A ++++ L
Sbjct: 85 ISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYYAANL 144
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSST---------- 170
+ ALE+IH ++HRD+K +NLL+ S+G++M+TDFG + L+ +
Sbjct: 145 LSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGR 204
Query: 171 -SSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLD 229
SSFVGTA +V+PELL ++ + SD+WA LY F G PF +E F +I ++
Sbjct: 205 RSSFVGTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRIQDIL 264
Query: 230 YHWIY-MVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKE 276
Y + ++ +L+ ++LV + SR T +IK H +F+ ID+ + E
Sbjct: 265 YTFSEDFPDENAKNLIERLLVKEQKSRLTSQEIKEHKFFESIDFEHLE 312
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 169 bits (429), Expect = 9e-42
Identities = 90/279 (32%), Positives = 156/279 (55%), Gaps = 11/279 (3%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T DF + +G GS+ VY+ + T +++A+K+ SK+HI +N+VK+V E+N L +
Sbjct: 90 TANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVL--I 147
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
+ HP ++ L+++F + E LYFVLD F+E+ ++ + ++ AL
Sbjct: 148 NNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALG 207
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
Y+H +++RDLKPENLLL +G L++TDFG+ +TS+F GT EY++PE++
Sbjct: 208 YLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKE--DMQGSKTTSTFCGTPEYLAPEII 265
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
L+ + D W +G +LY+ G PPF ++ ++KI+N + +S ++L++
Sbjct: 266 LKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELIT 325
Query: 246 KILVLDPDSRY----TLPQIKNHAWFQGIDW---TNKEL 277
+L D R I++H +F +DW N+EL
Sbjct: 326 GLLQKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNREL 364
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 168 bits (426), Expect = 2e-41
Identities = 93/267 (34%), Positives = 143/267 (52%), Gaps = 7/267 (2%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K T DF LG G + +VY A ++ AIKV K +IS + E +
Sbjct: 24 KFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLERE---IE 80
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+ +H NHP IIKLY F D++ +Y VL++AP RF+E +M ++ DA
Sbjct: 81 IQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADA 140
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
L Y H V+HRD+KPENLL+ S+G+L I DFG + + + + + GT +Y+ PE
Sbjct: 141 LSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPS----NKRQTMCGTMDYLPPE 196
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
++ + D+WA+G + Y+F G PPF E++ + I + + V + DL
Sbjct: 197 MVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDL 256
Query: 244 VSKILVLDPDSRYTLPQIKNHAWFQGI 270
+ ++LV+DP +R TL Q+K H W QG+
Sbjct: 257 IGRLLVVDPKARCTLEQVKEHYWIQGM 283
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 163 bits (413), Expect = 7e-40
Identities = 84/270 (31%), Positives = 141/270 (52%), Gaps = 13/270 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF K+ LG GS+ V ++T Q +A+K+ K+ ++ ++++ EK L +
Sbjct: 42 EDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV-- 99
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
N P +++L Y F D+ NLY V+++ P RF+E + + Q++ EY+
Sbjct: 100 -NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +++RDLKPENLL+ +G + +TDFG A + T + GT EY++PE++L
Sbjct: 159 HSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK-----GRTWTLCGTPEYLAPEIILS 213
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
N D WA+G ++Y+ G PPF + + +EKIV+ + S + DL+ +
Sbjct: 214 KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNL 273
Query: 248 LVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L +D R+ + IK H WF DW
Sbjct: 274 LQVDLTKRFGNLKNGVSDIKTHKWFATTDW 303
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 161 bits (408), Expect = 3e-39
Identities = 87/269 (32%), Positives = 140/269 (51%), Gaps = 13/269 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + LG GS+ V + +G +A+K+ K+ ++ +V++ EK L +
Sbjct: 51 DFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAI--- 107
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+ P ++ + ++F D+ NLY VL+F RF+E ++ + Q++ A EY+H
Sbjct: 108 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 167
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLKPENLL+ S G L ITDFG A + T + GT EY++PE++L
Sbjct: 168 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVK-----GRTWTLCGTPEYLAPEIILSK 222
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
N D WA+G ++Y+ G PPF + + +EKIV+ + S + DL+ +L
Sbjct: 223 GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLL 282
Query: 249 VLDPDSRY-----TLPQIKNHAWFQGIDW 272
+D RY + IKNH WF DW
Sbjct: 283 QVDLTKRYGNLKNGVADIKNHKWFGSTDW 311
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 161 bits (408), Expect = 3e-39
Identities = 87/269 (32%), Positives = 140/269 (51%), Gaps = 13/269 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + LG GS+ V + +G +A+K+ K+ ++ +V++ EK L +
Sbjct: 51 DFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAI--- 107
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+ P ++ + ++F D+ NLY VL+F RF+E ++ + Q++ A EY+H
Sbjct: 108 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 167
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLKPENLL+ S G L ITDFG A + T + GT EY++PE++L
Sbjct: 168 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVK-----GRTWTLCGTPEYLAPEIILSK 222
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
N D WA+G ++Y+ G PPF + + +EKIV+ + S + DL+ +L
Sbjct: 223 GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLL 282
Query: 249 VLDPDSRY-----TLPQIKNHAWFQGIDW 272
+D RY + IKNH WF DW
Sbjct: 283 QVDLTKRYGNLKNGVADIKNHKWFGSTDW 311
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 159 bits (403), Expect = 1e-38
Identities = 82/262 (31%), Positives = 137/262 (51%), Gaps = 13/262 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG GS+ V + TG +A+K+ K+ ++ ++++ EK L + N P ++K
Sbjct: 50 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV---NFPFLVK 106
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L ++F D+ NLY V+++ P RF+E + + Q++ EY+H +++R
Sbjct: 107 LEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYR 166
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLKPENLL+ +G + +TDFG A + T + GT EY++PE++L N D
Sbjct: 167 DLKPENLLIDQQGYIQVTDFGFAKRVK-----GRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSR 255
WA+G ++Y+ G PPF + + +EKIV+ + S + DL+ +L +D R
Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
Query: 256 Y-----TLPQIKNHAWFQGIDW 272
+ + IKNH WF DW
Sbjct: 282 FGNLKNGVNDIKNHKWFATTDW 303
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 158 bits (400), Expect = 2e-38
Identities = 94/293 (32%), Positives = 158/293 (53%), Gaps = 32/293 (10%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + + G++ V A +TG LFAIKV K +I +N V+ + E++ +L +
Sbjct: 827 DFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERD---ILINA 883
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+P +++ +Y+F SENLY V+++ +EA + ++ +++ ALEY+H
Sbjct: 884 RNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIAEVVLALEYLH 943
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASN--LAATDNLS-----STS---------- 171
VVHRDLKP+NLL++ +G + +TDFG++ + TD+LS +TS
Sbjct: 944 SEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPKLP 1003
Query: 172 ------SFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKI 225
S VGT +Y++PE+LL +D W+VG +LY+F G PPF ++ F+ I
Sbjct: 1004 TLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPFNADHPQQIFDNI 1063
Query: 226 VNLDYHWIYM---VSQHITDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDW 272
+N + W + +S DL+ ++L DP R ++K H++F+ IDW
Sbjct: 1064 LNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLGARGAAEVKQHSFFKDIDW 1116
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 157 bits (398), Expect = 4e-38
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 38/300 (12%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF + + G++ V+ A R+TG LFAIKV K +I +N V+ + E+N +L
Sbjct: 752 EDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERN---ILIS 808
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+P +++ +Y+F ENLY V+++ +E + ++ +++ ALEY+
Sbjct: 809 VRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALEYL 868
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSF------------ 173
H ++HRDLKP+NLL++ +G + +TDFG++ + +TD+LS SS
Sbjct: 869 HSVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDGSK 928
Query: 174 ---------------VGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE 218
VGT +Y++PE+LL +D W+VG +L++ G PPF E
Sbjct: 929 AQHSQGKDSRKKHAVVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPPFNAETP 988
Query: 219 LAAFEKIVNLDYHWIYM---VSQHITDLVSKILVLDPDSRYTLP---QIKNHAWFQGIDW 272
FE I+N D W + +S DL++K+L +P R ++K H +F+ I+W
Sbjct: 989 QQIFENIINRDIPWPNVPEEISYEAHDLINKLLTENPVQRLGATGAGEVKQHHFFKDINW 1048
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 157 bits (397), Expect = 5e-38
Identities = 93/282 (32%), Positives = 137/282 (47%), Gaps = 12/282 (4%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
S K P DF LG GSY V ++TG+LFA K K I+ + K + KN
Sbjct: 83 SGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVL--RAKGLEQTKNE 140
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
+L HP I +LYY F D + LY +L +AP E + +L
Sbjct: 141 RQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELT 200
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
AL ++H +V+RDLKPEN LL +EG +++TDFG++ +N + SFVGT EY +
Sbjct: 201 LALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSK---VAENGADCRSFVGTEEYCA 257
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT 241
PE+LL+ + D W++G +++ G+PPF N EKI + + V+
Sbjct: 258 PEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDAR 317
Query: 242 DLVSKILVLDPDSRY-------TLPQIKNHAWFQGIDWTNKE 276
D+++K L +P R IK H ++ IDW E
Sbjct: 318 DIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLE 359
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 157 bits (397), Expect = 5e-38
Identities = 82/270 (30%), Positives = 144/270 (52%), Gaps = 13/270 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
QDF +G G++ V+ +++ FA+KV S +I + ++V EK+ L ++H
Sbjct: 47 QDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSH 106
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
P +I+L++T+HD LY ++++ P RF+ + ++I A+EY+
Sbjct: 107 ---PFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H ++V+RDLKPEN+LL +G + +TDFG A L + T + GT EY++PE++
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-----VDRTWTLCGTPEYLAPEVIQS 218
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
D WA+G ++++ G PPF +N ++KI+ + + H+ DL+ K+
Sbjct: 219 KGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKL 278
Query: 248 LVLDPDSRY-----TLPQIKNHAWFQGIDW 272
LV+D R +K+H WF+ +DW
Sbjct: 279 LVVDRTRRLGNMKNGANDVKHHRWFRSVDW 308
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 157 bits (396), Expect = 6e-38
Identities = 88/266 (33%), Positives = 134/266 (50%), Gaps = 7/266 (2%)
Query: 1 MSRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
++R T DF LG G + VY A ++ + + A+KV K I E + E
Sbjct: 68 LTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRRE-- 125
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
+ + AH +HP I++LY F+D +Y +L++AP F+E T M +L
Sbjct: 126 -IEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEEL 184
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
DAL Y HG KV+HRD+KPENLLL +G+L I DFG + + + + GT +Y+
Sbjct: 185 ADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSL----RRKTMCGTLDYL 240
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
PE++ N D+W +G + Y+ G PPF + + +IV +D + V
Sbjct: 241 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGA 300
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
DL+SK+L +P R L Q+ H W
Sbjct: 301 QDLISKLLRHNPSERLPLAQVSAHPW 326
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 156 bits (395), Expect = 8e-38
Identities = 86/269 (31%), Positives = 137/269 (49%), Gaps = 13/269 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + LG GS+ V + T +A+K+ K+ ++ +V++ EK L +
Sbjct: 45 DFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI--- 101
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P ++ L Y F D+ NLY VL++ P RF+E ++ + Q++ A EY+H
Sbjct: 102 QFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLH 161
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLKPENLL+ S+G L +TDFG A + T + GT EY++PE++L
Sbjct: 162 YLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVK-----GRTWTLCGTPEYLAPEIILSK 216
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
N D WA+G ++Y+ G PPF + + +EKIV+ + + DL+ +L
Sbjct: 217 GYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLL 276
Query: 249 VLDPDSRY-----TLPQIKNHAWFQGIDW 272
+D RY + IKN WF DW
Sbjct: 277 QVDLTKRYGNLKAGVNDIKNQKWFASTDW 305
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 155 bits (393), Expect = 1e-37
Identities = 100/333 (30%), Positives = 166/333 (49%), Gaps = 18/333 (5%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P DF F + +G GS+ V A ++ +A+KV KK I+ + + K++ E+N L L
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--LK 152
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
+ HP ++ L+++F ++ LYFVLD+ F E + + ++ AL Y
Sbjct: 153 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGY 212
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H +V+RDLKPEN+LL S+G +++TDFG+ ++ S+TS+F GT EY++PE+L
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKE--NIEHNSTTSTFCGTPEYLAPEVLH 270
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
+ + D W +G +LY+ G PPF N ++ I+N ++ L+
Sbjct: 271 KQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEG 330
Query: 247 ILVLDPDSRY----TLPQIKNHAWFQGIDWTNKELIWKGIWQLFGNRNHNNFNGPSMMNK 302
+L D R +IK+H +F I+W +LI K I F + N +GP+
Sbjct: 331 LLQKDRTKRLGAKDDFMEIKSHVFFSLINW--DDLINKKITPPF----NPNVSGPN---- 380
Query: 303 QLHVIDTTIKNIPIQPRKRKPMKVTQTTSSIVE 335
+L D P+ K T+S+ E
Sbjct: 381 ELRHFDPEFTEEPVPNSIGKSPDSVLVTASVKE 413
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 155 bits (393), Expect = 1e-37
Identities = 89/301 (29%), Positives = 154/301 (50%), Gaps = 36/301 (11%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + + G++ V+ A R+TG FAIKV K +I +N ++ + E+N L +
Sbjct: 669 DFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILITV--- 725
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+P +++ +Y+F +NLY V+++ +E + ++ +L+ ALEY+H
Sbjct: 726 RYPFLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEYLH 785
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTS----------------- 171
K+VHRDLKP+NLL++ G + +TDFG+ S + +N S
Sbjct: 786 SLKIVHRDLKPDNLLIAYNGHIKLTDFGL-SKIGLINNTIDLSGHESDVSPRTNSHHFQK 844
Query: 172 ---------SFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAF 222
S VGT +Y++PE+LL + + +D W+ G +L++ G PPF F
Sbjct: 845 NQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGIPPFTASRPEKIF 904
Query: 223 EKIVNLDYHWIYM---VSQHITDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDWTNKE 276
+ I+N W + +S DL++++LV +P+ R ++K+H +FQG+DW N
Sbjct: 905 DNILNGKMPWPDVPGEMSYEAQDLINRLLVHEPEKRLGANGAAEVKSHPFFQGVDWENLA 964
Query: 277 L 277
L
Sbjct: 965 L 965
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 155 bits (393), Expect = 1e-37
Identities = 85/273 (31%), Positives = 149/273 (54%), Gaps = 10/273 (3%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P DF F + +G GS+ V A + G+++A+KV KK +++ + K++ E+N L L
Sbjct: 41 PTDFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVL--LK 98
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
+ HP ++ L+Y+F +E LYFVLDF F E + + ++ AL Y
Sbjct: 99 NVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGY 158
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVA-SNLAATDNLSSTSSFVGTAEYVSPELL 185
+H K+V+RDLKPEN+L+ S G +++TDFG+ +A +D +T++F GT EY++PE++
Sbjct: 159 LHSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISD---TTTTFCGTPEYLAPEVI 215
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
+ + D W +G +LY+ G PPF + ++ I++ VS ++
Sbjct: 216 RKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLRAWSILE 275
Query: 246 KILVLDPDSRY----TLPQIKNHAWFQGIDWTN 274
++L D +R +I+NH +F+ + W +
Sbjct: 276 ELLEKDRQNRLGAKEDFLEIQNHPFFESLSWAD 308
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 154 bits (389), Expect = 4e-37
Identities = 85/270 (31%), Positives = 141/270 (51%), Gaps = 8/270 (2%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P DF F + +G G+Y V A +S G +A+KV KK I+ + + ++ E++ L L
Sbjct: 92 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVL--LK 149
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
+ HP ++ L Y+F E LYFVLD+ RF E + + ++ A+ Y
Sbjct: 150 NVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGY 209
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H +++RDLKPEN+LL +G +++TDFG+ + +TS+F GT EY++PE+L
Sbjct: 210 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKE--GVEPEDTTSTFCGTPEYLAPEVLR 267
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
+ + D W +G +LY+ G PPF ++ +E I++ + DL+
Sbjct: 268 KEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQS 327
Query: 247 ILVLDP----DSRYTLPQIKNHAWFQGIDW 272
+L D S+ +IKNH +F I+W
Sbjct: 328 LLHKDQRQRLGSKADFLEIKNHVFFSPINW 357
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 154 bits (388), Expect = 5e-37
Identities = 83/273 (30%), Positives = 144/273 (52%), Gaps = 12/273 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + +G G++ VY+ + T +++A+KV K HI+ +N +Y+ E++ L +
Sbjct: 133 DFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKI--- 189
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+HP I++L Y+F LY VLDF F E + + +++ A+ ++H
Sbjct: 190 DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLH 249
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
++HRDLKPEN+L+ ++G +M+TDFG+A + + ++S GT EY++PE++
Sbjct: 250 EKGIMHRDLKPENILMDTDGHVMLTDFGLAKEF---EENTRSNSMCGTTEYMAPEIVRGK 306
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ +D W+VG +LY+ G PPF G +KIV +S ++ +L
Sbjct: 307 GHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQ-QKIVKDKIKLPQFLSNEAHAILKGLL 365
Query: 249 VLDPDSRY-----TLPQIKNHAWFQGIDWTNKE 276
+P+ R +IK H WF+GI+W E
Sbjct: 366 QKEPERRLGSGLSGAEEIKQHKWFKGINWKKLE 398
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 153 bits (387), Expect = 7e-37
Identities = 81/262 (30%), Positives = 138/262 (51%), Gaps = 13/262 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG GS+ V + TG +A+K+ +K+ ++ +V+++ EK L + + P ++K
Sbjct: 50 LGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI---DFPFLVK 106
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L ++F D+ LY V+++ P RF+E + Q++ A++Y+H ++HR
Sbjct: 107 LQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHR 166
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLKPENLL+ +G L +TDFG A + T + GT EY++PE++L N D
Sbjct: 167 DLKPENLLIDQQGYLQVTDFGFAKRVK-----GRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSR 255
WA+G ++Y+ G PPF + + +EKIV+ + +S + L+ +L +D R
Sbjct: 222 WWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKR 281
Query: 256 Y-----TLPQIKNHAWFQGIDW 272
+ + IKNH WF W
Sbjct: 282 FGNLRNGVGDIKNHKWFATTSW 303
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 153 bits (387), Expect = 7e-37
Identities = 83/262 (31%), Positives = 137/262 (51%), Gaps = 13/262 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
+G G++ V A D+ TG +A+KV + + ++ + ++V EK L L HP I+K
Sbjct: 69 IGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQL---KHPFIVK 125
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
+Y + DS +LY +++F P F+ + + + +++ ALEYIH +V+R
Sbjct: 126 MYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYR 185
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLKPENL+LS EG + + DFG A L T + GT +Y++PE L + N D
Sbjct: 186 DLKPENLMLSKEGHIKMADFGFAKELR-----DRTYTICGTPDYLAPESLARTGHNKGVD 240
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSR 255
WA+G ++Y+ G PPFRG+ ++ I+ + + DLV K+L +D R
Sbjct: 241 WWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLLEVDRTQR 300
Query: 256 Y-----TLPQIKNHAWFQGIDW 272
+K+H WF+ ++W
Sbjct: 301 IGCMKNGTQDVKDHKWFEKVNW 322
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 153 bits (386), Expect = 9e-37
Identities = 90/270 (33%), Positives = 140/270 (51%), Gaps = 12/270 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
QDF+F + LG GS+ V+ +AIKV KK I+ ++++ E+ +L+
Sbjct: 199 QDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERY---ILSR 255
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP I L+ TF D++NL+ V+DFA RF E K + ++I AL+Y+
Sbjct: 256 VQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYL 315
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H ++V+RDLKPENLLL G L I DFG A ++ S+ + GT +Y++PE++
Sbjct: 316 HHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVST----SNCCTLCGTPDYLAPEIISL 371
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
N +D W++G ++++ G PPF EN + +E I+ ++ S DL+S +
Sbjct: 372 KPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHL 431
Query: 248 LVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L D RY I H WF+ I W
Sbjct: 432 LQRDITCRYGNLKDGSMDIIMHPWFRDISW 461
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 151 bits (382), Expect = 3e-36
Identities = 90/267 (33%), Positives = 139/267 (51%), Gaps = 10/267 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F + +G GS+ V + R T +++A+K K HI+S ++V + E+ +LA N
Sbjct: 230 FELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERT---VLAQVN 286
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
+P I+ L ++F LY VL F F+ K ++ +L+ ALE +H
Sbjct: 287 NPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHE 346
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVAS-NLAATDNLSSTSSFVGTAEYVSPELLLQN 188
V++RDLKPEN+LL G + + DFG+ N+A TD T++F GT EY++PELLL +
Sbjct: 347 FNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDR---TNTFCGTPEYLAPELLLGH 403
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D W +G +LY+ G PPF EN + KI+ + + + DL+S +L
Sbjct: 404 GYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLL 463
Query: 249 VLDPDSRY---TLPQIKNHAWFQGIDW 272
P+ R +IKNH +F IDW
Sbjct: 464 TRAPEKRLGSGGAQEIKNHPFFDDIDW 490
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 151 bits (381), Expect = 3e-36
Identities = 87/271 (32%), Positives = 134/271 (49%), Gaps = 8/271 (2%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF ++LG G + VY RSTG + A+KV K+ II N K E L
Sbjct: 103 DFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSL--- 159
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP + K Y FHD + +Y ++++ FN+ ++ Q+ +AL+Y+H
Sbjct: 160 NHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMH 219
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
++HRD+KPEN+L+ + +TDFG S + +N T GT +Y+SPE++
Sbjct: 220 KKNIIHRDIKPENILIGFNNVIKLTDFGW-SIINPPENRRKT--VCGTIDYLSPEMVESR 276
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ + D WA+G + ++ G PPF E + +++I LD +SQ DL+ K+L
Sbjct: 277 EYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLL 336
Query: 249 VLDPDSRYTLPQIKNHAWF--QGIDWTNKEL 277
DP R L +K H W W NK L
Sbjct: 337 KYDPKDRMRLGDVKMHPWILRNKPFWENKRL 367
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 150 bits (380), Expect = 4e-36
Identities = 83/271 (30%), Positives = 145/271 (52%), Gaps = 11/271 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F + LG GS+ V A + T +++AIK+ K I+ ++ V+ EK L+L A
Sbjct: 377 DFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAA-- 434
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP + L+ +F S+ L+FV+++ +F+E+ + + ++ AL+++H
Sbjct: 435 KHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLH 494
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
V++RDLK +N+LL +EG + DFG+ DNL TS+F GT +Y++PE+L +
Sbjct: 495 RNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNL--TSTFCGTPDYIAPEILQEM 552
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ D WA+G ++Y+ G PPF +NE FE I+N D + +S+ +++ +
Sbjct: 553 EYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFM 612
Query: 249 VLDPDSRYTL-------PQIKNHAWFQGIDW 272
+ R I+ H +F+ IDW
Sbjct: 613 TKNAGKRLGCVVSQGGEDAIRAHPFFREIDW 643
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 150 bits (379), Expect = 6e-36
Identities = 78/259 (30%), Positives = 137/259 (52%), Gaps = 7/259 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF LG G + VY A ++ + + A+KV K + K + + + +H
Sbjct: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQL---EKAGVEHQLRREVEIQSH 187
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP I++LY FHD+ +Y +L++AP +F+E T ++ +L +AL Y
Sbjct: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYC 247
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +V+HRD+KPENLLL S G+L I DFG + + + S ++ GT +Y+ PE++
Sbjct: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPS----SRRTTLCGTLDYLPPEMIEG 303
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
+ D+W++G + Y+F G PPF +++I +++ + V++ DL+S++
Sbjct: 304 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRL 363
Query: 248 LVLDPDSRYTLPQIKNHAW 266
L +P R L ++ H W
Sbjct: 364 LKHNPSQRPMLREVLEHPW 382
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 150 bits (379), Expect = 6e-36
Identities = 89/285 (31%), Positives = 148/285 (51%), Gaps = 17/285 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P+ F + LG GS+ V+ K R +G ++A+KV K + KV+ K
Sbjct: 98 KADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATL----KVRDRQRTKL 153
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
N+LAH +HP I+KL+Y F LY +LDF F E K ++ +L
Sbjct: 154 ERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAEL 213
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
ALE++H +V+RDLKPEN+LL ++G + +TDFG++ A D+ T SF GT EY+
Sbjct: 214 TLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKE--AIDSEKKTYSFCGTVEYM 271
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE++ + + +D W++G ++++ G PF+G + +I+ + ++Q
Sbjct: 272 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 331
Query: 241 TDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDWT---NKEL 277
L+ + + +R + +IK HA+F ID+ NKE+
Sbjct: 332 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEI 376
Score = 104 bits (259), Expect = 5e-22
Identities = 69/270 (25%), Positives = 128/270 (46%), Gaps = 23/270 (8%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
D+ E++G+G++S V+K ++T + +A+K+ K + +V LL H
Sbjct: 453 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI---------LLRHS 503
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRF-NEAWTKHFMCQLIDALEYI 127
+H ++KL+ + D +Y + + +E M L++A++Y+
Sbjct: 504 HHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYL 563
Query: 128 HGCKVVHRDLKPENLLLSSE----GKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
H +V HRDL N+L + + L I DFG A A + + T + TA++V+PE
Sbjct: 564 HSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY--TAQFVAPE 621
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPF-RGENEL--AAFEKI----VNLDYHWIYMV 236
+L + + D+W++G +L+ G PF G N+ +++ +++ + +
Sbjct: 622 VLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTI 681
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAW 266
S DLV K+L +DP+ R T Q H W
Sbjct: 682 SDEAKDLVRKMLDVDPNRRVTAKQALQHKW 711
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 150 bits (379), Expect = 6e-36
Identities = 89/285 (31%), Positives = 148/285 (51%), Gaps = 17/285 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P+ F + LG GS+ V+ K R +G ++A+KV K + KV+ K
Sbjct: 41 KADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATL----KVRDRQRTKL 96
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
N+LAH +HP I+KL+Y F LY +LDF F E K ++ +L
Sbjct: 97 ERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAEL 156
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
ALE++H +V+RDLKPEN+LL ++G + +TDFG++ A D+ T SF GT EY+
Sbjct: 157 TLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKE--AIDSEKKTYSFCGTVEYM 214
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE++ + + +D W++G ++++ G PF+G + +I+ + ++Q
Sbjct: 215 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 274
Query: 241 TDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDWT---NKEL 277
L+ + + +R + +IK HA+F ID+ NKE+
Sbjct: 275 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEI 319
Score = 104 bits (259), Expect = 5e-22
Identities = 69/270 (25%), Positives = 128/270 (46%), Gaps = 23/270 (8%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
D+ E++G+G++S V+K ++T + +A+K+ K + +V LL H
Sbjct: 396 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI---------LLRHS 446
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRF-NEAWTKHFMCQLIDALEYI 127
+H ++KL+ + D +Y + + +E M L++A++Y+
Sbjct: 447 HHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYL 506
Query: 128 HGCKVVHRDLKPENLLLSSE----GKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
H +V HRDL N+L + + L I DFG A A + + T + TA++V+PE
Sbjct: 507 HSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY--TAQFVAPE 564
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPF-RGENEL--AAFEKI----VNLDYHWIYMV 236
+L + + D+W++G +L+ G PF G N+ +++ +++ + +
Sbjct: 565 VLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTI 624
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAW 266
S DLV K+L +DP+ R T Q H W
Sbjct: 625 SDEAKDLVRKMLDVDPNRRVTAKQALQHKW 654
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 150 bits (378), Expect = 8e-36
Identities = 82/270 (30%), Positives = 142/270 (52%), Gaps = 9/270 (3%)
Query: 7 PQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHII-SENKVKYVTIEKNTL 62
P+DF + +G G Y V+ K G ++A+KV +K+ + +E +++ E+ L
Sbjct: 20 PKDFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKIL 79
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ N P + L+Y F +E LY VL+F + E + + ++ ++I
Sbjct: 80 ETI---NSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIIL 136
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
A+E++HG +V+RDLKP+N++L+ G +++TDFG+ T +F GT EY++P
Sbjct: 137 AIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKG--EKTLTFCGTHEYMAP 194
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
E++ + + D+WA+G ++Y G PPF GE + I+ +S D
Sbjct: 195 EMIRKVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKD 254
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQGIDW 272
L+ +I+ DP R T+P IK H +F+ IDW
Sbjct: 255 LIKRIIKRDPTLRITIPDIKEHEFFEEIDW 284
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 149 bits (376), Expect = 1e-35
Identities = 82/274 (29%), Positives = 142/274 (50%), Gaps = 12/274 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF + +G G++ VY+ + T +++A+KV K I+ +N +Y+ E++ L +
Sbjct: 138 EDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKI-- 195
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+HP I++L Y+F LY VLDF F E + + +++ A+ ++
Sbjct: 196 -DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 254
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H ++HRDLKPEN+L+ +G +M+TDFG+A + + ++S GT EY++PE++
Sbjct: 255 HEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEF---EENTRSNSMCGTTEYMAPEIVRG 311
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
+ +D W+VG +LY+ G PPF G +KIV +S L+ +
Sbjct: 312 KGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQ-QKIVKDKIKLPQFLSNEAHALLKGL 370
Query: 248 LVLDPDSRY-----TLPQIKNHAWFQGIDWTNKE 276
L +P+ R +IK H WF+ I+W E
Sbjct: 371 LQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLE 404
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 149 bits (375), Expect = 2e-35
Identities = 78/270 (28%), Positives = 140/270 (50%), Gaps = 13/270 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
++F LG GS+ V+ R G+ +A+KV K+ ++ +V++ E+ L+++ H
Sbjct: 85 KNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTH 144
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
P II+++ TF D++ ++ ++D+ RF K + ++ ALEY+
Sbjct: 145 ---PFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYL 201
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +++RDLKPEN+LL G + ITDFG A + T + GT +Y++PE++
Sbjct: 202 HSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP-----DVTYTLCGTPDYIAPEVVST 256
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
N D W+ G ++Y+ G PF N + +EKI+N + + ++ + DL+S++
Sbjct: 257 KPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRL 316
Query: 248 LVLDPDSRYTLPQ-----IKNHAWFQGIDW 272
+ D R Q +KNH WF+ + W
Sbjct: 317 ITRDLSQRLGNLQNGTEDVKNHPWFKEVVW 346
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 148 bits (373), Expect = 3e-35
Identities = 83/274 (30%), Positives = 134/274 (48%), Gaps = 13/274 (4%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K T DF LG GS+ V+ G+ +AIKV K+ ++ +V++ E+ L
Sbjct: 64 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLK 123
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
L+ HP +I+++ TF D+ N++ V+D+ RF K + ++I A
Sbjct: 124 LV---EHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILA 180
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
LEY+H +++RDLKPEN+LL G + ITDFG A + T + GT +Y++PE
Sbjct: 181 LEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTV-----TWTLCGTPDYIAPE 235
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
++ N D W++G ++Y+ G PF + +EKI+ + + DL
Sbjct: 236 VITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDL 295
Query: 244 VSKILVLDPDSRYTLPQ-----IKNHAWFQGIDW 272
+SK++ D R Q IK H WF + W
Sbjct: 296 LSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVW 329
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 148 bits (373), Expect = 3e-35
Identities = 79/275 (28%), Positives = 146/275 (52%), Gaps = 10/275 (3%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
+++T DF + + LG G++ V ++++G+ +A+K+ K+ II++++V + E L
Sbjct: 141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL 200
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ HP + L Y+F + L FV+++ F+E T+ + +++
Sbjct: 201 K---NTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVS 257
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL+Y+H K+V+RDLK ENL+L +G + ITDFG+ + ++ +F GT EY++P
Sbjct: 258 ALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKE--GITDAATMKTFCGTPEYLAP 315
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
E+L N D W +G ++Y+ G PF ++ FE I+ D + +S
Sbjct: 316 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKS 375
Query: 243 LVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L+S +L+ DP+ R +I H++F G++W
Sbjct: 376 LLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNW 410
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 148 bits (373), Expect = 3e-35
Identities = 80/260 (30%), Positives = 132/260 (50%), Gaps = 10/260 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF LG G + VY A + + + A+KV K+ I K K + + +
Sbjct: 21 DFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQI---EKYKIHHQLRREMEIQTSL 77
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ FHD+E ++ +L++A E ++ L AL Y H
Sbjct: 78 RHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCH 137
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
G V+HRD+KPENLLL EG+L I DFG + + + + GT +Y++PE++
Sbjct: 138 GKCVIHRDIKPENLLLDHEGRLKIADFG-----WSVQSSNKRKTMCGTLDYLAPEMVENR 192
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYM--VSQHITDLVSK 246
++ D W +G + Y+F G PPF E++ F++I+ +D + VS+ +L+S+
Sbjct: 193 DHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQ 252
Query: 247 ILVLDPDSRYTLPQIKNHAW 266
+LV DP R ++ +I H W
Sbjct: 253 LLVKDPSKRLSIEKIMQHPW 272
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 147 bits (372), Expect = 4e-35
Identities = 77/259 (29%), Positives = 136/259 (51%), Gaps = 7/259 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF LG G + VY A ++ + + A+KV K + K + + + +H
Sbjct: 130 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQL---EKAGVEHQLRREVEIQSH 186
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP I++LY FHD+ +Y +L++AP +F+E T + ++ +AL Y
Sbjct: 187 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSYC 246
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +V+HRD+KPENLLL S G+L I DFG + + + S ++ GT +Y+ PE++
Sbjct: 247 HSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPS----SRRTTLCGTLDYLPPEMIEG 302
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
+ D+W++G + Y+F G PPF +++I +++ + V++ DL+S++
Sbjct: 303 RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRL 362
Query: 248 LVLDPDSRYTLPQIKNHAW 266
L +P R L ++ H W
Sbjct: 363 LKHNPSQRPMLREVLEHPW 381
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 147 bits (372), Expect = 4e-35
Identities = 82/270 (30%), Positives = 141/270 (51%), Gaps = 5/270 (1%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF + LG GS+ V+ A + T Q FAIK K ++ ++ V+ +EK L+L
Sbjct: 378 EDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA-- 435
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP + ++ TF ENL+FV+++ +F+ + + ++I L+++
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +V+RDLK +N+LL +G + I DFG+ D + T++F GT +Y++PE+LL
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGD--AKTNTFCGTPDYIAPEILLG 553
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
K N D W+ G +LY+ G PF G++E F I + + + + DL+ K+
Sbjct: 554 QKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKL 613
Query: 248 LVLDPDSRYTL-PQIKNHAWFQGIDWTNKE 276
V +P+ R + I+ H F+ I+W E
Sbjct: 614 FVREPEKRLGVRGDIRQHPLFREINWEELE 643
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 147 bits (372), Expect = 4e-35
Identities = 92/306 (30%), Positives = 157/306 (51%), Gaps = 39/306 (12%)
Query: 3 RKRTP-QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
R RT DF + + G++ V+ A R+TG LFAIKV K +I +N V+ + E++
Sbjct: 882 RDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADMIRKNAVESILAERD- 940
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
+L + +P +++ +Y+F +NLY V+++ E + ++ +++
Sbjct: 941 --ILINVRNPFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLEEDIVRVYIAEVV 998
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA--SNLAATDNL-----SSTS--- 171
ALEY+H VVHRDLKP+NLL++ +G + +TDFG++ + +TD+L S TS
Sbjct: 999 LALEYLHSEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLD 1058
Query: 172 -------------------SFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPP 212
S VGT +Y++PE+LL +D W+VG +L++ G PP
Sbjct: 1059 EEESRLAASEEQLERRKKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILFELIVGIPP 1118
Query: 213 FRGENELAAFEKIVNLDYHWIYM---VSQHITDLVSKILVLDPDSRY---TLPQIKNHAW 266
F E+ F+ I+N W ++ +S D++ + L DP R ++K H +
Sbjct: 1119 FNAEHPQQIFDNILNRKIPWPHVPEEMSAEAHDIIDRFLTEDPHQRLGARGAAEVKQHIF 1178
Query: 267 FQGIDW 272
F+ I+W
Sbjct: 1179 FKDINW 1184
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 147 bits (370), Expect = 6e-35
Identities = 83/266 (31%), Positives = 130/266 (48%), Gaps = 7/266 (2%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
R+ T DF LG G + VY A + + + A+KV K I E + E +
Sbjct: 2 RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRRE---I 58
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ AH HP I++LY FHD+ +Y +L++AP + +E T + ++ D
Sbjct: 59 EIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVAD 118
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL Y H KV+HRD+KPENLLL G++ I DFG + + L + GT +Y+ P
Sbjct: 119 ALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTP----LPERKTMCGTLDYLPP 174
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
E++ + D+W +G + Y+ G PPF + + +I+ +D + + D
Sbjct: 175 EMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARD 234
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQ 268
L+S++L P R L QI H W Q
Sbjct: 235 LISRLLRYQPLERLPLAQILKHPWVQ 260
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 146 bits (369), Expect = 8e-35
Identities = 84/269 (31%), Positives = 137/269 (50%), Gaps = 10/269 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F + LG G + VY A ++ TG + A+K K ++ K V E + L H N
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 177
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
I++LY FHD + +Y +L+FA RF+E ++ Q+ +AL Y+H
Sbjct: 178 ---ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHK 234
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
V+HRD+KPEN+LL +G++ ++DFG ++ A N +T GT +Y+ PE++ +
Sbjct: 235 KHVIHRDIKPENILLGIDGEIKLSDFG--WSVHAPSNRRTT--LCGTLDYLPPEMVEGKE 290
Query: 190 SNFCSDIWAVGCMLYQFTQGTPPFRG-ENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D+W++G + Y+F G PPF A +++I +D V DL+S++L
Sbjct: 291 HTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLL 350
Query: 249 VLDPDSRYTLPQIKNHAWFQGI--DWTNK 275
+P+ R +L Q+ H W WT K
Sbjct: 351 QHNPEKRMSLEQVMRHPWIVKYKDSWTRK 379
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 145 bits (367), Expect = 1e-34
Identities = 81/276 (29%), Positives = 134/276 (48%), Gaps = 13/276 (4%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
S K + DF LG GS+ V+ G+ +A+K K I+ +V++ E+
Sbjct: 80 SGKYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRM 139
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
L++++H P II+++ TF DS+ ++ V+D+ RF K + ++
Sbjct: 140 LSIVSH---PFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVC 196
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
ALEY+H +++RDLKPEN+LL G + ITDFG A + T + GT +Y++
Sbjct: 197 LALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP-----DVTYTLCGTPDYIA 251
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT 241
PE++ N D W+ G ++Y+ G PF N + +E I+N + +
Sbjct: 252 PEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQ 311
Query: 242 DLVSKILVLDPDSRYTLPQ-----IKNHAWFQGIDW 272
DL+ K++ D R Q +KNH WF + W
Sbjct: 312 DLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIW 347
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 145 bits (367), Expect = 1e-34
Identities = 87/272 (31%), Positives = 142/272 (51%), Gaps = 10/272 (3%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
PQDF LG G++ VY+ + T +++A+KV SKK I+ +N++ + E+N L A
Sbjct: 409 PQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTA 468
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
+ P I+ L ++F +LY V D+ RF+E K ++ +L+ ALE+
Sbjct: 469 SKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEH 528
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H +V+RDLKPEN+LL + G + + DFG L+ D T++F GT EY++PELLL
Sbjct: 529 LHDNDIVYRDLKPENILLDANGNIALCDFG----LSKADLKDRTNTFCGTTEYLAPELLL 584
Query: 187 QNKS-NFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY-MVSQHITDLV 244
D W++G ++++ G PF EN ++KI + ++SQ V
Sbjct: 585 DETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFV 644
Query: 245 SKILVLDPDSRYTL----PQIKNHAWFQGIDW 272
+L +P R +++ H +F IDW
Sbjct: 645 KGLLNRNPKHRLGAIDDGRELRAHPFFADIDW 676
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 145 bits (366), Expect = 2e-34
Identities = 93/276 (33%), Positives = 138/276 (49%), Gaps = 17/276 (6%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F FKE LG G++S V A +++TG+LFA+K KK + K K +IE N + +L
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL----KGKESSIE-NEIAVLRKIK 77
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
H I+ L + +LY V+ + E + Q++DA+ Y+H
Sbjct: 78 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHR 137
Query: 130 CKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+VHRDLKPENLL S E K+MI+DFG++ D +S+ GT YV+PE+L
Sbjct: 138 MGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTAC---GTPGYVAPEVLA 194
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY-----HWIYMVSQHIT 241
Q + D W++G + Y G PPF EN+ FE+I+ +Y +W +S
Sbjct: 195 QKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYW-DDISDSAK 253
Query: 242 DLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKEL 277
D + ++ DP+ RYT Q H W G NK +
Sbjct: 254 DFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNI 289
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 145 bits (366), Expect = 2e-34
Identities = 90/296 (30%), Positives = 149/296 (49%), Gaps = 15/296 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F + LG GS+ V A + T +++AIKV K II ++ V EK L L A
Sbjct: 407 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAA-- 464
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP + L+ F + L+FV+++ RF + + ++ AL+++H
Sbjct: 465 NHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLH 524
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
V++RDLK +N+LL EG + DFG+ L++T F GT +Y++PE+L +
Sbjct: 525 THGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTT--FCGTPDYIAPEILKEQ 582
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ D WA+G ++Y+ G PPF +NE F+ I++ D + +S+ ++ L
Sbjct: 583 EYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFL 642
Query: 249 VLDPDSRYTLP----QIKNHAWFQGIDWTNKELIWKGIWQLF-----GNRNHNNFN 295
+P+ R +I+ H +F +DW KEL + I F R+ NNF+
Sbjct: 643 TKNPEQRLGCTGDENEIRKHPFFAKLDW--KELEKRNIKPPFRPKMKNPRDANNFD 696
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 144 bits (363), Expect = 4e-34
Identities = 86/277 (31%), Positives = 137/277 (49%), Gaps = 14/277 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P F + LG GSY V+ K GQL+A+KV K + ++V+ K
Sbjct: 53 KADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVR----SKM 108
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
++LA NHP I+KL+Y F LY +LDF F E K ++ +L
Sbjct: 109 ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 168
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
AL+++H +++RDLKPEN+LL EG + ITDFG++ A D+ SF GT EY+
Sbjct: 169 ALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKE--AIDHDKRAYSFCGTIEYM 226
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE++ + +D W+ G ++++ G+ PF+G++ I+ +S
Sbjct: 227 APEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEA 286
Query: 241 TDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L+ + +P +R + +IK H +F IDW
Sbjct: 287 QSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDW 323
Score = 119 bits (298), Expect = 1e-26
Identities = 77/269 (28%), Positives = 122/269 (44%), Gaps = 24/269 (8%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ KE +G GSYS + V ++T +A+K+ K +++ LL +G
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI---------LLRYGQ 465
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II L + D + +Y V++ F+E +C + ++Y+H
Sbjct: 466 HPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHS 525
Query: 130 CKVVHRDLKPENLLLSSEG----KLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
VVHRDLKP N+L E + + DFG A L A + L T + TA +V+PE+L
Sbjct: 526 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY--TANFVAPEVL 583
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY--------HWIYMVS 237
+ + DIW++G +LY G PF + E + + +W +S
Sbjct: 584 KRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNW-DSIS 642
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAW 266
D+VSK+L +DP R T Q+ H W
Sbjct: 643 DAAKDVVSKMLHVDPHQRLTAMQVLKHPW 671
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 144 bits (362), Expect = 5e-34
Identities = 83/258 (32%), Positives = 137/258 (52%), Gaps = 10/258 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F LG G + V+ A +R G + A+K+ K I + + + E + + ++
Sbjct: 10 FEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRRE---IEIHSNLK 66
Query: 70 HPGIIKLYYTFHDSENLYFVLDFA-PXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I+++Y FHD +N+Y +L++A +F E T ++ Q++ AL Y+
Sbjct: 67 HPNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIRQVMLALTYMK 126
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
C V+HRD+KPENLLL S+ +L I DFG A A + +F GT EY++PE++ +
Sbjct: 127 ECNVIHRDIKPENLLLGSDNQLKIADFGWAVYNADKRRM----TFCGTMEYLAPEMVNND 182
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDYHWIYMVSQHITDLVSK 246
+ D+W +G + Y+F G PF +N A++KI +L Y +S + +D +S+
Sbjct: 183 IHDSGIDLWCLGILTYEFLMGKTPFESKNRNMREAYKKINSLKYTIPETISSNASDFISR 242
Query: 247 ILVLDPDSRYTLPQIKNH 264
+LVL P R L + NH
Sbjct: 243 LLVLSPGDRMELTEALNH 260
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 144 bits (362), Expect = 5e-34
Identities = 84/256 (32%), Positives = 135/256 (51%), Gaps = 9/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LGHG+++ VY A + T + AIKV K+ ++ + ++ K +++L HP I++
Sbjct: 32 LGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHI---KREISILRRVRHPNIVQ 88
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +YFV+++ E K+F QLI A+ + H V HR
Sbjct: 89 LFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYFQ-QLISAVTFCHARGVYHR 147
Query: 136 DLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
DLKPENLLL G L ++DFG++ S+ D L T F GT YV+PE+L + +
Sbjct: 148 DLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHT--FCGTPAYVAPEVLARKGYDAA 205
Query: 194 S-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
DIW+ G +L+ G PF N +A ++KI ++ S +T L+SK+L +P
Sbjct: 206 KVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRWFSTELTRLLSKLLETNP 265
Query: 253 DSRYTLPQIKNHAWFQ 268
+ R+T P+I ++WF+
Sbjct: 266 EKRFTFPEIMENSWFK 281
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 143 bits (360), Expect = 9e-34
Identities = 82/271 (30%), Positives = 128/271 (46%), Gaps = 15/271 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
D+ K LG GS+ V +R +G +A K SK I+ +V +V EKN L +
Sbjct: 46 DYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTF- 104
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P + L ++ D ++LY VL +F E + + Q+ ALEY+H
Sbjct: 105 --PNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLH 162
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
C +++RDLKPEN+++ G L +TDFG A + + T + GT EY+ PE++
Sbjct: 163 HCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVE-----TRTMTLCGTPEYLPPEIIQSK 217
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDYHWIYMVSQHITDLVSK 246
D WA G ++++F G PF N ++ + KI DY S + LV
Sbjct: 218 PYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDH 277
Query: 247 ILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
+L +D R+ IK H WF+ ++W
Sbjct: 278 LLQVDLSKRFGNLINGNRDIKEHEWFKDVEW 308
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 142 bits (359), Expect = 1e-33
Identities = 86/270 (31%), Positives = 140/270 (51%), Gaps = 10/270 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+F F LG GS+ V A + TG L+A+KV K I+ ++ V+ EK L+L
Sbjct: 353 NFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLAR-- 410
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP + +L+ F + L+FV++F RF+EA + + ++I AL ++H
Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 470
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLK +N+LL EG + DFG+ N +T++F GT +Y++PE+L +
Sbjct: 471 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKE--GICNGVTTATFCGTPDYIAPEILQEM 528
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D WA+G +LY+ G PF ENE FE I+N + + + + T ++ +
Sbjct: 529 LYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFM 588
Query: 249 VLDPDSRY-TLPQ-----IKNHAWFQGIDW 272
+P R +L Q I H +F+ IDW
Sbjct: 589 TKNPTMRLGSLTQGGEHAILRHPFFKEIDW 618
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 142 bits (359), Expect = 1e-33
Identities = 76/272 (27%), Positives = 144/272 (52%), Gaps = 8/272 (2%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F+ + LG GS+ V + + +A+K K I+ ++ + IE+ L L +
Sbjct: 238 FNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLILASQC- 296
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
P + +L+ +F +E L+FV+++ +F+EA T+ + C+++ AL+++H
Sbjct: 297 -PFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQFLHT 355
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+++RDLK +N+LL +G + + DFG+A +N S+F GT +Y+SPE++
Sbjct: 356 NNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNREN-GMASTFCGTPDYISPEIIKGQL 414
Query: 190 SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILV 249
N D W+ G ++Y+ G PF GE E F+ I+N ++ +S+ +S +
Sbjct: 415 YNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSALFD 474
Query: 250 LDPDSRYTLPQ-----IKNHAWFQGIDWTNKE 276
+P++R +P+ I+ H +F+G+DW E
Sbjct: 475 RNPNTRLGMPECPDGPIRQHCFFRGVDWKRFE 506
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 142 bits (359), Expect = 1e-33
Identities = 76/272 (27%), Positives = 144/272 (52%), Gaps = 8/272 (2%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F+ + LG GS+ V + + +A+K K I+ ++ + IE+ L L +
Sbjct: 375 FNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRVLILASQC- 433
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
P + +L+ +F +E L+FV+++ +F+EA T+ + C+++ AL+++H
Sbjct: 434 -PFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQFLHT 492
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+++RDLK +N+LL +G + + DFG+A +N S+F GT +Y+SPE++
Sbjct: 493 NNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNREN-GMASTFCGTPDYISPEIIKGQL 551
Query: 190 SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILV 249
N D W+ G ++Y+ G PF GE E F+ I+N ++ +S+ +S +
Sbjct: 552 YNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSALFD 611
Query: 250 LDPDSRYTLPQ-----IKNHAWFQGIDWTNKE 276
+P++R +P+ I+ H +F+G+DW E
Sbjct: 612 RNPNTRLGMPECPDGPIRQHCFFRGVDWKRFE 643
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 142 bits (359), Expect = 1e-33
Identities = 82/260 (31%), Positives = 134/260 (51%), Gaps = 9/260 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+F LG G + VY A ++ + + A+KV K+ I N V E + + +H
Sbjct: 153 NFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRRE---IEIQSHL 209
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXX--XRFNEAWTKHFMCQLIDALEY 126
HP I++LY FHD +Y +L++AP RF+E + ++ L AL Y
Sbjct: 210 RHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLY 269
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H ++HRD+KPENLLL +G L I DFG + + + S + GT +Y+ PE++
Sbjct: 270 LHERDIIHRDIKPENLLLGHKGVLKIADFGWSVH----EPNSMRMTLCGTVDYLPPEMVQ 325
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
D+W++G + ++ G PF +N ++KI+ +DY +S+ + L+SK
Sbjct: 326 GKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISK 385
Query: 247 ILVLDPDSRYTLPQIKNHAW 266
+LVL+P R L Q+ H W
Sbjct: 386 LLVLNPQHRLPLDQVMVHPW 405
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 142 bits (358), Expect = 2e-33
Identities = 88/276 (31%), Positives = 145/276 (51%), Gaps = 10/276 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + +G GS+ V + + T +++A+K K +I+S+ +V + E+ +LA
Sbjct: 343 DFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERT---VLARV 399
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+ P I+ L ++F E LY VL F RF+ A ++ ++ +L+ AL+ +H
Sbjct: 400 DCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLH 459
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
V++RDLKPEN+LL +G + + DFG+ L DN T +F GT EY++PE+LL
Sbjct: 460 KLDVIYRDLKPENILLDYQGHIALCDFGLC-KLNMKDN-DKTDTFCGTPEYLAPEILLGQ 517
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D W +G +LY+ G PP+ EN ++KI+ + DL+ +L
Sbjct: 518 GYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLL 577
Query: 249 VLDPDSRYTL---PQIKNHAWFQGIDWTNKELIWKG 281
DP R + +I+NH +F+ I W K+L+ KG
Sbjct: 578 SRDPSRRLGVNGTDEIRNHPFFKDISW--KKLLLKG 611
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 142 bits (357), Expect = 2e-33
Identities = 86/281 (30%), Positives = 146/281 (51%), Gaps = 28/281 (9%)
Query: 8 QDFSF-KERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
+DFS E +G G+++TV KA++R+TG+ FA+K+ SK+ +I + VT E L L
Sbjct: 195 KDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVI--GNMDGVTRELEVLQKL- 251
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
NHP I++L + D+E+ Y V++F E + Q++ A++Y
Sbjct: 252 --NHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKY 309
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLM--ITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
IH + HRDLKP+N+L+ + ++ ITDFG+A N S +F GT YV+PE+
Sbjct: 310 IHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAK---VQGNGSFMKTFCGTLAYVAPEV 366
Query: 185 LL-------------QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYH 231
+ +N+ + D+W++GC++Y G PF G + +++I YH
Sbjct: 367 IRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYH 426
Query: 232 ----WIYMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
+ +S+ D + +L +DP++R T + NH W +
Sbjct: 427 EGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIK 467
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 141 bits (356), Expect = 3e-33
Identities = 78/266 (29%), Positives = 139/266 (51%), Gaps = 10/266 (3%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
++ T DF + LG G + VY A ++ + + A+KV K + +++V++ + +
Sbjct: 12 KRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQL-QQSQVEHQL--RREV 68
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ +H HP I++LY F+D + +Y +L++A F+E ++ L
Sbjct: 69 EIQSHLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLAR 128
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL Y HG V+HRD+KPENLL+ ++G+L I DFG + + + GT +Y+ P
Sbjct: 129 ALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG-----WSVHTFNRRRTMCGTLDYLPP 183
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHW--IYMVSQHI 240
E++ + + DIW++G + Y+F G PPF +++IV +D + +VS
Sbjct: 184 EMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSA 243
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
DL+S++LV + R L ++ H W
Sbjct: 244 KDLISQMLVKESTQRLALHKLLEHPW 269
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 141 bits (355), Expect = 4e-33
Identities = 83/275 (30%), Positives = 135/275 (48%), Gaps = 12/275 (4%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P F + LG GS+ V+ K GQL+A+KV K + ++V+ K
Sbjct: 67 KADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVR----TKM 122
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
++L NHP I+KL+Y F LY +LDF F E K ++ +L
Sbjct: 123 ERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAEL 182
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
AL+++H +V+RDLKPEN+LL G + +TDFG++ + D SF GT EY+
Sbjct: 183 ALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKE--SVDQEKKAYSFCGTVEYM 240
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE++ + + +D W+ G ++++ GT PF+G++ I+ +S
Sbjct: 241 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 300
Query: 241 TDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDW 272
L+ + +P +R + +IK H +F IDW
Sbjct: 301 QSLLRMLFKRNPANRLGSEGVEEIKRHLFFANIDW 335
Score = 117 bits (292), Expect = 7e-26
Identities = 81/269 (30%), Positives = 121/269 (44%), Gaps = 24/269 (8%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ KE +G GSYS + + +T FA+K+ K +++ L+ +G
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI---------LMRYGQ 476
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II L F D +Y V D F+E + + ++Y+H
Sbjct: 477 HPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHC 536
Query: 130 CKVVHRDLKPENLLLSSEG----KLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
VVHRDLKP N+L E + I DFG A L + L T + TA +V+PE+L
Sbjct: 537 QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCY--TANFVAPEVL 594
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPF-RGENEL--AAFEKIVNLDY-----HWIYMVS 237
+Q + DIW++G + Y G PF G N+ +I N + +W +S
Sbjct: 595 MQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNW-DNIS 653
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAW 266
DL+S +L +DP RYT QI H+W
Sbjct: 654 DGAKDLLSHMLHMDPHQRYTAEQILKHSW 682
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 141 bits (355), Expect = 4e-33
Identities = 81/279 (29%), Positives = 137/279 (49%), Gaps = 14/279 (5%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIE 58
S K P F + LG GS+ V+ K +G L+A+KV K + ++V+
Sbjct: 54 SEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR----T 109
Query: 59 KNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMC 118
K ++LA NHP ++KL+Y F LY +LDF F E K ++
Sbjct: 110 KMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 169
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
+L L+++H +++RDLKPEN+LL EG + +TDFG++ A D+ SF GT E
Sbjct: 170 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE--AIDHEKKAYSFCGTVE 227
Query: 179 YVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQ 238
Y++PE++ + + +D W+ G ++++ G+ PF+G++ I+ +S
Sbjct: 228 YMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLST 287
Query: 239 HITDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L+ + +P +R +IK H ++ IDW
Sbjct: 288 EAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDW 326
Score = 115 bits (288), Expect = 2e-25
Identities = 82/266 (30%), Positives = 120/266 (44%), Gaps = 24/266 (9%)
Query: 13 KERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPG 72
KE +G GSYS + V ++T +A+KV K +++ LL +G HP
Sbjct: 421 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI---------LLRYGQHPN 471
Query: 73 IIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKV 132
II L + D +++Y V + F+E + + +EY+H V
Sbjct: 472 IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGV 531
Query: 133 VHRDLKPENLLLSSEGK----LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
VHRDLKP N+L E L I DFG A L A + L T + TA +V+PE+L +
Sbjct: 532 VHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCY--TANFVAPEVLKRQ 589
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY--------HWIYMVSQHI 240
+ DIW++G +LY G PF E + + +W VS+
Sbjct: 590 GYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW-NTVSETA 648
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
DLVSK+L +DP R T Q+ H W
Sbjct: 649 KDLVSKMLHVDPHQRLTAKQVLQHPW 674
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 141 bits (355), Expect = 4e-33
Identities = 86/274 (31%), Positives = 138/274 (49%), Gaps = 10/274 (3%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K T +DF F + LG G++ V ++ T +L+AIK+ K II+ +V + E L
Sbjct: 187 KITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQ 246
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
HP + +L Y+F + L FV+ FA F+E + + +++ A
Sbjct: 247 RC---KHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLA 303
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
L Y+H C +V+RD+K ENLLL +G + I DFG+ + + TS+F GT EY++PE
Sbjct: 304 LGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGD--KTSTFCGTPEYLAPE 361
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
+L + C D W VG ++Y+ G PF ++ FE I+ D + +SQ L
Sbjct: 362 VLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTL 421
Query: 244 VSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
++ +LV DP R +I +F+ +DW
Sbjct: 422 LTGLLVKDPTQRLGGGPEDALEICRADFFRTVDW 455
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 141 bits (355), Expect = 4e-33
Identities = 91/319 (28%), Positives = 151/319 (46%), Gaps = 52/319 (16%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
+K DF +G G++ V ++STG ++A+K K ++ +V++V E+N
Sbjct: 113 QKMGVDDFELLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEMLRRGQVEHVKAERN-- 170
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+LA + P I+KL Y+F D E+LY ++++ P E T+ ++ Q I
Sbjct: 171 -VLAEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDMMTLLMRKDTLREDETRFYVAQTIL 229
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNL--------------------A 162
A+E IH VHRD+KP+NLL++ G + ++DFG++ +L A
Sbjct: 230 AIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSKSLESKNFPDFKAELVDRSTKPAA 289
Query: 163 ATDNLSS-----------------------TSSFVGTAEYVSPELLLQNKSNFCSDIWAV 199
D LS S VGT +Y++PE+LL+ D W++
Sbjct: 290 EHDRLSKPPSAPRRTQQEQLLHWQQNRRTLAFSTVGTPDYIAPEVLLKKGYGMECDWWSL 349
Query: 200 GCMLYQFTQGTPPFRGENELAAFEKIVN----LDYHWIYMVSQHITDLVSKILVLDPDSR 255
G ++++ G PPF E LA KIVN L + +S + DL+ ++L
Sbjct: 350 GAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFPDEAKLSIEVKDLIRRLLCNVEQRL 409
Query: 256 YT--LPQIKNHAWFQGIDW 272
T + +IK H WF+G++W
Sbjct: 410 GTKGVHEIKAHPWFRGVEW 428
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 140 bits (354), Expect = 5e-33
Identities = 82/277 (29%), Positives = 136/277 (48%), Gaps = 14/277 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P F + LG GS+ V+ K QL+A+KV K + ++V+ K
Sbjct: 62 KADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR----TKM 117
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
++L NHP I+KL+Y F LY +LDF F E K ++ +L
Sbjct: 118 ERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 177
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
AL+++H +++RDLKPEN+LL EG + +TDFG++ + D+ SF GT EY+
Sbjct: 178 ALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE--SIDHEKKAYSFCGTVEYM 235
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE++ + +D W+ G ++++ GT PF+G++ I+ +S
Sbjct: 236 APEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEA 295
Query: 241 TDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L+ + +P +R + +IK H++F IDW
Sbjct: 296 QSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 332
Score = 115 bits (288), Expect = 2e-25
Identities = 79/268 (29%), Positives = 119/268 (43%), Gaps = 22/268 (8%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ KE +G GSYS + + ++T FA+K+ K +++ LL +G
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI---------LLRYGQ 472
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II L + D + +Y V + F+E + + +EY+H
Sbjct: 473 HPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHA 532
Query: 130 CKVVHRDLKPENLLLSSEG----KLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
VVHRDLKP N+L E + I DFG A L A + L T + TA +V+PE+L
Sbjct: 533 QGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY--TANFVAPEVL 590
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV-------NLDYHWIYMVSQ 238
+ + DIW++G +LY G PF + E + +L + VS
Sbjct: 591 KRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSD 650
Query: 239 HITDLVSKILVLDPDSRYTLPQIKNHAW 266
DLVSK+L +DP R T + H W
Sbjct: 651 TAKDLVSKMLHVDPHQRLTAALVLRHPW 678
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 140 bits (353), Expect = 6e-33
Identities = 86/291 (29%), Positives = 141/291 (47%), Gaps = 27/291 (9%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
PQ F LG G VY +R T Q+FA+KV +K +I K+K V E+ +LA
Sbjct: 321 PQSFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQE---ILA 377
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR--FNEAWTKHFMCQLIDAL 124
+HP I+ LY++F + LY +++ E K + +++ AL
Sbjct: 378 TSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAAL 437
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSS--------------- 169
EY+H ++RDLKPEN+LL G +M++DF ++ + +
Sbjct: 438 EYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGF 497
Query: 170 -TSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNL 228
T+SFVGT EY++PE++ N D W +G ++Y+ G PF+G+N F I+
Sbjct: 498 RTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTK 557
Query: 229 DYHWIY--MVSQHITDLVSKILVLDP----DSRYTLPQIKNHAWFQGIDWT 273
D + + VS++ DL+ K+L + S+ IK H +F+ + W+
Sbjct: 558 DVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWS 608
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 140 bits (352), Expect = 8e-33
Identities = 79/270 (29%), Positives = 139/270 (51%), Gaps = 8/270 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF+F LG G++ V A +S QL+AIKV K+ I+ ++V+ EK +
Sbjct: 681 EDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANR 740
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP ++ L+ F +YFV+DF +F+ + + ++ AL+Y
Sbjct: 741 ERHPFLVNLHSCFQTETRIYFVMDFV-SGGDLMLHIQQEQFSRRRAQFYAAEVCLALKYF 799
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +++RDLK +N+LLS +G + + D+G+ DN +T++F GT E+++PE+LL+
Sbjct: 800 HDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDN--TTATFCGTPEFMAPEILLE 857
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
+ D WA G ++YQ G PFRGE+E F+ I++ + + + + ++ ++
Sbjct: 858 QQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQQL 917
Query: 248 LVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L DP R + H +F I+W
Sbjct: 918 LTRDPKKRLGSGPNDAEDVMTHPFFSNINW 947
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 140 bits (352), Expect = 8e-33
Identities = 85/274 (31%), Positives = 132/274 (48%), Gaps = 12/274 (4%)
Query: 7 PQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
P+DF + LG G Y V+ K GQ+FA+KV K I+ K T K N
Sbjct: 80 PEDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHT--KAERN 137
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+L P I L Y F LY +L++ F E K ++ +++ +
Sbjct: 138 ILEAVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVS 197
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
LE++H +++RDLKPEN+LL + G + +TDFG+ D T +F GT EY++PE
Sbjct: 198 LEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGD--QKTHTFCGTIEYMAPE 255
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
+L++ D W++G +++ G PPF EN +KI+ +S DL
Sbjct: 256 ILMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDL 315
Query: 244 VSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
+ K+L D+R +IK+HA+F+ DW
Sbjct: 316 IKKLLKRHVDTRLGAGLSDAEEIKSHAFFKTTDW 349
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 139 bits (350), Expect = 1e-32
Identities = 84/258 (32%), Positives = 126/258 (48%), Gaps = 6/258 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF LG GS++ VY+A TG AIK+ KK + V+ V KN + +
Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRV---KNEVKIHCQ 66
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMCQLIDALEY 126
HP I++LY F DS +Y VL+ + F+E +HFM Q+I + Y
Sbjct: 67 LKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H ++HRDL NLLL+ + I DFG+A+ L T GT Y+SPE+
Sbjct: 127 LHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYT--LCGTPNYISPEIAT 184
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
++ SD+W++GCM Y G PPF + K+V DY +S DL+ +
Sbjct: 185 RSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQ 244
Query: 247 ILVLDPDSRYTLPQIKNH 264
+L +P R +L + +H
Sbjct: 245 LLRRNPADRLSLSSVLDH 262
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 139 bits (350), Expect = 1e-32
Identities = 81/274 (29%), Positives = 137/274 (49%), Gaps = 17/274 (6%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
Q+ LG G + V ++ FA+K KKHI+ + ++V EK L L
Sbjct: 451 QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCS 510
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
P I+KLY TF D++ +Y +L+ F+E +K + + +A +Y+
Sbjct: 511 ---PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYL 567
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +++RDLKPENL+L +EG L + DFG A + + T +F GT EYV+PE++L
Sbjct: 568 HRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQK---TWTFCGTPEYVAPEVILN 624
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV----NLDYHWIYMVSQHITDL 243
+F D W++G ++Y+ G PPF G +++ + I+ +D+ +++ DL
Sbjct: 625 KGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFP--RKITRRPEDL 682
Query: 244 VSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
+ ++ +P R + IK H W G +W
Sbjct: 683 IRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNW 716
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 139 bits (350), Expect = 1e-32
Identities = 83/277 (29%), Positives = 139/277 (49%), Gaps = 12/277 (4%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P+ F LG G Y V+ K +TG++FA+KV K I+ K T K
Sbjct: 85 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHT--KA 142
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
N+L HP I+ L Y F LY +L++ F E ++ ++
Sbjct: 143 ERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEI 202
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
AL ++H +++RDLKPEN++L+ +G + +TDFG+ + + + T +F GT EY+
Sbjct: 203 SMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKE--SIHDGTVTHTFCGTIEYM 260
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE+L+++ N D W++G ++Y G PPF GEN +KI+ + ++Q
Sbjct: 261 APEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEA 320
Query: 241 TDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
DL+ K+L + SR +++ H +F+ I+W
Sbjct: 321 RDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINW 357
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 139 bits (350), Expect = 1e-32
Identities = 77/266 (28%), Positives = 138/266 (50%), Gaps = 10/266 (3%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
++ T DF + LG G + VY A ++ + + A+KV K + +++V++ + +
Sbjct: 24 KRWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQL-QQSQVEHQL--RREV 80
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ +H HP I++LY F+D + +Y +L++A F+E ++ L
Sbjct: 81 EIQSHLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLAR 140
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL Y HG V+HRD+KPENLL+ ++G+L I DFG + + + GT +Y+ P
Sbjct: 141 ALIYCHGKHVIHRDIKPENLLIGAQGELKIADFG-----WSVHTFNRRRTMCGTLDYLPP 195
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHW--IYMVSQHI 240
E++ + + DIW++G + Y+F G PPF + +IV +D + ++S
Sbjct: 196 EMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASA 255
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
DL+S++LV + R L ++ H W
Sbjct: 256 KDLISQMLVKESSQRLPLHKLLEHPW 281
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 139 bits (350), Expect = 1e-32
Identities = 76/254 (29%), Positives = 134/254 (51%), Gaps = 5/254 (1%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LGHG+++ VY A + +G AIKV K+ I+ V ++ K +++L HP I+
Sbjct: 80 LGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHI---KREISILRRVRHPYIVH 136
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +YFV+++ R E + + QLI ++ + HG V HR
Sbjct: 137 LFEVMATKSKIYFVMEYV-GGGELFNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHR 195
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC-S 194
DLKPENLLL ++G L ++DFG+++ +F GT Y++PE+L + + +
Sbjct: 196 DLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKA 255
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
D+W+ G +L+ G PF +N + ++KI ++ S + L++++L +PD+
Sbjct: 256 DVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPDT 315
Query: 255 RYTLPQIKNHAWFQ 268
R T+P+I + WF+
Sbjct: 316 RITIPEIMKNRWFK 329
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 139 bits (349), Expect = 2e-32
Identities = 86/276 (31%), Positives = 142/276 (51%), Gaps = 10/276 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + +G GS+ V + + T +++A+K K +I+S+++V + E+ +LA
Sbjct: 346 DFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERT---VLARV 402
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+ P I+ L ++F E LYFVL F RF+ + + + +L+ AL+ +H
Sbjct: 403 DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLH 462
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
VV+RDLKPEN+LL +G + + DFG+ D+ T +F GT EY++PELLL
Sbjct: 463 KLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDD--KTDTFCGTPEYLAPELLLGL 520
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D W +G +LY+ G PP+ E+ ++KI+ + + DL+ +L
Sbjct: 521 GYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLL 580
Query: 249 VLDPDSRY---TLPQIKNHAWFQGIDWTNKELIWKG 281
DP R +I+NH +F + W K L+ KG
Sbjct: 581 SRDPTRRLGYNGADEIRNHPFFSQLSW--KRLLMKG 614
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 138 bits (347), Expect = 3e-32
Identities = 81/256 (31%), Positives = 131/256 (50%), Gaps = 9/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LGHG+++ VY A + +G+ AIKV K+ ++ + ++ K +++L HP I++
Sbjct: 34 LGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHI---KREISILRRVRHPNIVQ 90
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +YFV+++ R E + + QLI A+ + H V HR
Sbjct: 91 LFEVMATKSKIYFVMEYVKGGELFNKVAKG-RLKEEMARKYFQQLISAVSFCHFRGVYHR 149
Query: 136 DLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
DLKPENLLL G L ++DFG++ S+ D L T F GT YV+PE+L + +
Sbjct: 150 DLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHT--FCGTPAYVAPEVLARKGYDGA 207
Query: 194 S-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
DIW+ G +L+ G PF N +A ++KI D+ I L+ ++L P
Sbjct: 208 KVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCPRWFPVEINRLLIRMLETKP 267
Query: 253 DSRYTLPQIKNHAWFQ 268
+ R+T+P I +WF+
Sbjct: 268 ERRFTMPDIMETSWFK 283
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 137 bits (346), Expect = 4e-32
Identities = 82/273 (30%), Positives = 146/273 (53%), Gaps = 10/273 (3%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P DF + +G G++ VY + T +++A+KV SKK I+ +V + E++ L +
Sbjct: 263 PDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTS 322
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
+ P I+ L ++F ++LY V D+ RF E K ++ +L+ AL+
Sbjct: 323 AADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQA 382
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVA-SNLAATDNLSSTSSFVGTAEYVSPELL 185
+H +V+RDLKPEN+LL +G + + DFG++ +NL+ ++T +F GT +Y++PE++
Sbjct: 383 LHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVG---TTTRTFCGTTDYLAPEVI 439
Query: 186 LQNKS-NFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY-MVSQHITDL 243
L + D W++G +LY+ T G PF +N ++ IV + ++S DL
Sbjct: 440 LDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDL 499
Query: 244 VSKILVLDPDSRY----TLPQIKNHAWFQGIDW 272
+ +L +P R + ++ H +F GIDW
Sbjct: 500 IKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDW 532
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 137 bits (345), Expect = 5e-32
Identities = 85/296 (28%), Positives = 151/296 (50%), Gaps = 26/296 (8%)
Query: 2 SRKRTPQ--DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEK 59
+++ +PQ DF + + +G+Y VY ++T Q FA+K +K ++I N+V+ V E+
Sbjct: 825 AQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAER 884
Query: 60 NTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQ 119
+ +L+ ++P ++ +Y +F ++L V+++ + + +
Sbjct: 885 D---ILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAE 941
Query: 120 LIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFG--------VASNLAATDNLSSTS 171
+ A+EY+H +VHRDLKP+NLL+++ G + +TDFG +A+NL S T
Sbjct: 942 TVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETR 1001
Query: 172 SF-----VGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV 226
F GT EY++PE++L+ D W++G +LY+F G PF GE F V
Sbjct: 1002 QFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTV 1061
Query: 227 NLDYHW----IYMVSQHITDLVSKILVLDPDSRYTLP----QIKNHAWFQGIDWTN 274
N D W + V D++S++L +P R ++K H +F G+DW +
Sbjct: 1062 NDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNS 1117
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 137 bits (344), Expect = 7e-32
Identities = 77/256 (30%), Positives = 133/256 (51%), Gaps = 9/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ V+ A DR TGQ A+K+ +KK +++ + K ++++ +HP I+K
Sbjct: 27 LGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPAL--ANNIKREISIMRRLSHPNIVK 84
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ ++F ++F R +E ++ + QLI A+ Y H V HR
Sbjct: 85 LHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHR 144
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTS---SFVGTAEYVSPELLLQNKSNF 192
DLKPENLL+ G L ++DFG++ A TD + + GT YV+PE+L +
Sbjct: 145 DLKPENLLIDENGNLKVSDFGLS---ALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEG 201
Query: 193 CS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLD 251
D+W+ G +L+ G PF N + ++KI +Y + +S + VS++L ++
Sbjct: 202 AKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDIN 261
Query: 252 PDSRYTLPQIKNHAWF 267
P++R T+ +I WF
Sbjct: 262 PETRITIDEILKDPWF 277
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 137 bits (344), Expect = 7e-32
Identities = 81/281 (28%), Positives = 133/281 (46%), Gaps = 15/281 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
K P F LG GS+ V+ K + + G L+A+KV K + +++V+ N
Sbjct: 193 KADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVR----STN 248
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
+LA H I++L+Y F LY +LDF F E K ++ +L
Sbjct: 249 ERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 308
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
A+ ++H +++RDLKPEN+LL G + +TDFG++ + S T SF GT EY+
Sbjct: 309 ALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPL---DGSKTYSFCGTVEYM 365
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
+PE++ + +F +D W+ G ++Y+ G PF G+ +I+ +S
Sbjct: 366 APEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEA 425
Query: 241 TDLVSKILVLDPDSR-----YTLPQIKNHAWFQGIDWTNKE 276
L+ + +P +R + IK H +F IDW E
Sbjct: 426 QSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLE 466
Score = 104 bits (260), Expect = 4e-22
Identities = 69/272 (25%), Positives = 131/272 (47%), Gaps = 15/272 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+++ + LG G++S R++ + +A+KV K + + + + +L +G
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP I+ LY + D+ + Y V++ + E+ + + A+ Y+H
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 129 GCKVVHRDLKPENLLLSSEGK----LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
VVHRDLKP N++ +S + L + D G A L A + L T + TA +V+PE+
Sbjct: 687 EHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCY--TANFVAPEV 744
Query: 185 LLQNKSNFCSDIWAVGCMLYQFTQGTPPFR---GENELAAFEKIVN--LDY---HWIYMV 236
L + + DIW++G +LY G PF ++ ++I + +D+ W ++
Sbjct: 745 LKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWA-LI 803
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
S +L+ ++L + P++R T +I H W +
Sbjct: 804 SVPAKELLRQMLHIVPENRPTAARILEHDWLR 835
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 136 bits (342), Expect = 1e-31
Identities = 78/271 (28%), Positives = 138/271 (50%), Gaps = 11/271 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+F+F + LG GS+ V A + +++A+KV K I+ ++ V EK L L
Sbjct: 407 EFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR-- 464
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP + +LY F + L+FV+++ +F+E ++ + ++ AL ++H
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
V++RDLK +N+LL +EG + DFG+ N +T++F GT +Y++PE+L +
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKE--GILNGVTTTTFCGTPDYIAPEILQEL 582
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ D WA+G ++Y+ G PPF +NE FE I++ D + +S+ ++ +
Sbjct: 583 EYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFM 642
Query: 249 VLDPDSRYTL-------PQIKNHAWFQGIDW 272
+P R IK H +F+ IDW
Sbjct: 643 TKNPHKRLGCVASQNGEDAIKQHPFFKEIDW 673
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 136 bits (342), Expect = 1e-31
Identities = 82/258 (31%), Positives = 126/258 (48%), Gaps = 6/258 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF LG GS++ VY+A +G AIK+ KK + V+ V +N + +
Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRV---QNEVKIHCQ 66
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMCQLIDALEY 126
HP I++LY F DS +Y VL+ + F+E +HFM Q+I + Y
Sbjct: 67 LKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLY 126
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H ++HRDL NLLL+ + I DFG+A+ L T GT Y+SPE+
Sbjct: 127 LHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYT--LCGTPNYISPEIAT 184
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
++ SD+W++GCM Y G PPF + K+V DY +S DL+ +
Sbjct: 185 RSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQ 244
Query: 247 ILVLDPDSRYTLPQIKNH 264
+L +P R +L + +H
Sbjct: 245 LLRRNPADRLSLSSVLDH 262
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 136 bits (342), Expect = 1e-31
Identities = 85/307 (27%), Positives = 146/307 (46%), Gaps = 46/307 (14%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF +G G++ V +++TGQ++A+K K ++ +V++V E+N LLA
Sbjct: 123 DFDLLTMIGKGAFGEVRVCREKTTGQVYAMKKLKKAEMLRRGQVEHVRAERN---LLAEV 179
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+ I+KLY +F D ++LY V+++ P E K ++ + + A+E IH
Sbjct: 180 DSNYIVKLYCSFQDDDHLYLVMEYLPGGDMMTLLMRKDTLTEEEAKFYVAETVLAIESIH 239
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVA----------------SNLAATDNLSSTS- 171
+HRD+KP+NLLL G L ++DFG+ SN + ST+
Sbjct: 240 RHNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSAIGENDFSNNSNGSTEQEAGSTAP 299
Query: 172 --------------------SFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTP 211
S VGT +Y++PE+LL+ D W++G ++Y+ G P
Sbjct: 300 KRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYP 359
Query: 212 PFRGENELAAFEKIVNLDYHWIY----MVSQHITDLVSKIL--VLDPDSRYTLPQIKNHA 265
PF ++ ++ KIVN H + ++S+ DL++ +L V ++K H
Sbjct: 360 PFYSDDPMSTCRKIVNWKSHLKFPEEAILSREAKDLINSLLCSVRRRLGSKGADELKAHT 419
Query: 266 WFQGIDW 272
WF+ +DW
Sbjct: 420 WFETVDW 426
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 135 bits (341), Expect = 1e-31
Identities = 79/271 (29%), Positives = 138/271 (50%), Gaps = 8/271 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
QDF LG G + V A ++T ++FAIK K I++ ++V + EK +
Sbjct: 655 QDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNS 714
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP ++ L+ F E++ FV+++A F+E + ++ L+Y+
Sbjct: 715 VRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV-FSEPRAVFYAACVVLGLQYL 773
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H K+V+RDLK +NLLL +EG + I DFG+ + TS+F GT E+++PE+L +
Sbjct: 774 HEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGD--RTSTFCGTPEFLAPEVLTE 831
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
D W +G ++Y+ G PF G++E F+ IVN + + +S ++ ++
Sbjct: 832 TSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRL 891
Query: 248 LVLDPDSRYTLPQ-----IKNHAWFQGIDWT 273
L +P+ R + +K H +F+ IDW+
Sbjct: 892 LRRNPERRLGASEKDAEDVKKHPFFRLIDWS 922
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 135 bits (341), Expect = 1e-31
Identities = 82/278 (29%), Positives = 134/278 (47%), Gaps = 14/278 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DFSF LG GS+ V A R + +L+AIK+ K I+ ++ V +EK L L G
Sbjct: 350 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 409
Query: 69 NHPG-----IIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
PG + +L+ TF + LYFV+++ +F E + ++
Sbjct: 410 --PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 467
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
L ++H +++RDLK +N++L +EG + ITDFG+ ++T +F GT +Y++PE
Sbjct: 468 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPG--TTTRTFCGTPDYIAPE 525
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
++ D W+ G +LY+ G PPF GE+E F+ I+ + +S+ +
Sbjct: 526 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAI 585
Query: 244 VSKILVLDPDSRYTL-----PQIKNHAWFQGIDWTNKE 276
L P R P I+ H +F+ IDW E
Sbjct: 586 CKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLE 623
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 135 bits (341), Expect = 1e-31
Identities = 77/270 (28%), Positives = 137/270 (50%), Gaps = 12/270 (4%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+D LG G + V + V ++ + +A+K+ +K HI+ + +V E+ +L
Sbjct: 272 EDLQRVSTLGMGGFGRV-ELVRSASSRTYALKIMNKAHIVETKQESHVVSERR---ILMQ 327
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
++ I+++Y T+ DSE +Y +++ RF+ T+ + ++ALEY+
Sbjct: 328 CDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYL 387
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +V+RDLKPEN+LL G + DFG A L N T +F GTAEYV+PE++L
Sbjct: 388 HRKNIVYRDLKPENMLLDRNGWPKLVDFGFAKKL---KNGGRTWTFCGTAEYVAPEIVLN 444
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN--LDYHWIYMVSQHITDLVS 245
+ DIWA+G + + G+PPF + + + I+ + W V++ D++
Sbjct: 445 KGHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMML 504
Query: 246 KILVLDPDSRY---TLPQIKNHAWFQGIDW 272
+ +P R + +I++H WF D+
Sbjct: 505 SLCKYEPTERLGFGDIGEIRHHIWFDNFDF 534
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 135 bits (341), Expect = 1e-31
Identities = 76/273 (27%), Positives = 136/273 (48%), Gaps = 9/273 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F + +G GS+ V A R T +L+A+KV K II + ++ EK L L G
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILAL--SG 427
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P ++ ++ F + L+FV+++ RF E+ + ++ AL ++H
Sbjct: 428 RPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLH 487
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLK +N+LL EG + + DFG++ +T +F GT Y++PE++ +
Sbjct: 488 ERDIIYRDLKLDNILLDGEGHVKLVDFGLSKE--GVTERQTTRTFCGTPNYMAPEIVSYD 545
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ +D W+ G +L++F G PF G++E F I + + S D+++ L
Sbjct: 546 PYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFL 605
Query: 249 VLDPDS-----RYTLPQIKNHAWFQGIDWTNKE 276
P++ RY +I H +F+ +DW E
Sbjct: 606 TKKPNNRLGAGRYARQEITTHPFFRNVDWDKAE 638
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 135 bits (341), Expect = 1e-31
Identities = 80/277 (28%), Positives = 139/277 (49%), Gaps = 10/277 (3%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
+K T ++F F + LG G++ V +++T +L+AIK+ K+ II +++V + E L
Sbjct: 178 KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL 237
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
NHP +I L Y+F ++ L FV+ + F E T+ + ++I
Sbjct: 238 KST---NHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIIS 294
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL Y+H +++RDLK ENLLL +G + + DFG+ +T +F GT EY++P
Sbjct: 295 ALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGR--TTKTFCGTPEYLAP 352
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
E+L N D W G ++Y+ G PF + F I+ + + ++ +
Sbjct: 353 EVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKN 412
Query: 243 LVSKILVLDPDSRY-----TLPQIKNHAWFQGIDWTN 274
L++ +L DP R + +I+ H +F I+WT+
Sbjct: 413 LLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTD 449
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 135 bits (341), Expect = 1e-31
Identities = 86/260 (33%), Positives = 125/260 (48%), Gaps = 6/260 (2%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T +D+ + LG G ++TVYKA T Q AIK+ KK I V E + L
Sbjct: 10 TIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRL 69
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMCQLIDAL 124
HP +++LY F D+ +Y VL+ A R F E + Q++ L
Sbjct: 70 ---KHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGL 126
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
Y+H ++HRD+ NLLLS E + I DFG+A+ L D T GT Y+SPE+
Sbjct: 127 LYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMT--MCGTPNYISPEV 184
Query: 185 LLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLV 244
+ + +D+W+VGCMLY G PPF + + K+V +Y +S DL+
Sbjct: 185 VSRTSHGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLI 244
Query: 245 SKILVLDPDSRYTLPQIKNH 264
+K+L P R TL + H
Sbjct: 245 NKLLKKLPHERITLEAVLCH 264
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 135 bits (341), Expect = 1e-31
Identities = 76/255 (29%), Positives = 128/255 (49%), Gaps = 9/255 (3%)
Query: 17 GHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG--NHPGII 74
G G ++ Y+ +D T +FA K+ SKK +I N+ EK + H NHP I+
Sbjct: 32 GKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQK-----EKTAQEITIHRSLNHPNIV 86
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVH 134
K + F DS+N+Y VL+ E ++++ Q+I ++Y+H +++H
Sbjct: 87 KFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRIIH 146
Query: 135 RDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCS 194
RDLK NL L+ + I DFG+A+ + T GT Y++PE+L + +F
Sbjct: 147 RDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKT--LCGTPNYIAPEILTKKGHSFEV 204
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
DIW++GC++Y G PPF + + KI +Y + + D+V +L +P+S
Sbjct: 205 DIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPNPES 264
Query: 255 RYTLPQIKNHAWFQG 269
R + Q+ N + +G
Sbjct: 265 RPAIGQLLNFEFLKG 279
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 135 bits (340), Expect = 2e-31
Identities = 78/274 (28%), Positives = 137/274 (49%), Gaps = 10/274 (3%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K T DF + + LG G++ V +++TG+ +A+K+ K+ II++++V + E L
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+ HP + L Y F + L FV+++A F E + + +++ A
Sbjct: 206 ---NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSA 262
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
LEY+H VV+RD+K ENL+L +G + ITDFG+ + ++ +F GT EY++PE
Sbjct: 263 LEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKE--GISDGATMKTFCGTPEYLAPE 320
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
+L N D W +G ++Y+ G PF ++ FE I+ + + +S L
Sbjct: 321 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSL 380
Query: 244 VSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
++ +L DP R ++ H +F I+W
Sbjct: 381 LAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINW 414
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 135 bits (340), Expect = 2e-31
Identities = 81/273 (29%), Positives = 138/273 (49%), Gaps = 5/273 (1%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
S K +F F + LG GS+ V + G+ FAIK K ++ ++ V+ +EK
Sbjct: 341 SSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRV 400
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
L L A +P + L TF ++L+FV++F RF + +++
Sbjct: 401 LTLAAE--NPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIM 458
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
L+++H +++RDLK +N+LL +G + I DFG+ ++ +ST F GT +Y++
Sbjct: 459 CGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRAST--FCGTPDYIA 516
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT 241
PE+L K F D W+ G +LY+ G PF G++E FE I H+ +++
Sbjct: 517 PEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESK 576
Query: 242 DLVSKILVLDPDSRYTLP-QIKNHAWFQGIDWT 273
D++ K+ +P R + IK H +F+ I+WT
Sbjct: 577 DILEKLFEREPTKRLGVTGNIKIHPFFKTINWT 609
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 135 bits (340), Expect = 2e-31
Identities = 84/262 (32%), Positives = 132/262 (50%), Gaps = 12/262 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIE---KNTLNLL 65
++ + LGHGS++ V A+ +TG AIK I++ +K+K + IE + + +L
Sbjct: 18 NYRIGKTLGHGSFAKVKLALHVATGHKVAIK------ILNRSKIKNMGIEIKVQREIKIL 71
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
HP II+ Y ++Y V+++ + E +H Q+I +E
Sbjct: 72 RFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVE 131
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
Y H +VHRDLKPEN+LL S+ + I DFG+ SN+ + TS G+ Y +PE++
Sbjct: 132 YCHRNMIVHRDLKPENVLLDSQCNIKIVDFGL-SNVMHDGHFLKTS--CGSPNYAAPEVI 188
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
DIW+ G +LY GT PF EN FEKI Y +S DL+
Sbjct: 189 SGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIP 248
Query: 246 KILVLDPDSRYTLPQIKNHAWF 267
++L++DP R ++ +I+ H WF
Sbjct: 249 RMLMVDPTMRISITEIRQHPWF 270
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 135 bits (339), Expect = 3e-31
Identities = 81/272 (29%), Positives = 132/272 (47%), Gaps = 12/272 (4%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F LG GS+ V ++T +LFAIKV K II ++ V+ EK L L
Sbjct: 412 DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKP 471
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
+ ++ L+ F + LYFV++F +F E + ++ L ++H
Sbjct: 472 SF--LVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLH 529
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLK +N++L +G + ITDFG+ D ++T +F GT +Y++PE++L
Sbjct: 530 SKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGD--ATTKTFCGTPDYIAPEIILYQ 587
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D WA G +L++ G PPF GE+E F I + + +S+ L +L
Sbjct: 588 PYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALL 647
Query: 249 VLDP--------DSRYTLPQIKNHAWFQGIDW 272
+ +P D IK H +F+ IDW
Sbjct: 648 IKNPSKRLGCTGDDESASRDIKEHPFFRRIDW 679
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 134 bits (337), Expect = 4e-31
Identities = 85/294 (28%), Positives = 140/294 (46%), Gaps = 30/294 (10%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
PQ F LG G V+ ++ T +++A+KV SK +I NK+K V E+ +LA
Sbjct: 493 PQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQE---ILA 549
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR--FNEAWTKHFMCQLIDAL 124
NHP I+ LY++F + LY +++ E + + ++ AL
Sbjct: 550 TSNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAAL 609
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA----------------SNLAATDNLS 168
EY+H ++RDLKPEN+LL G +M++DF ++ S L T S
Sbjct: 610 EYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICS 669
Query: 169 S---TSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKI 225
T+SFVGT EY++PE++ N D W +G ++Y+ G PF+G+N F I
Sbjct: 670 DGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNI 729
Query: 226 V--NLDYHWIYMVSQHITDLVSKILVLDPDSR----YTLPQIKNHAWFQGIDWT 273
+ + + +S+ DL+ K+L + R +K H +F+ + W+
Sbjct: 730 LKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWS 783
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 134 bits (337), Expect = 4e-31
Identities = 89/303 (29%), Positives = 137/303 (44%), Gaps = 39/303 (12%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
TP F LG G VY +S +LFA+K+ +K+ +I +KV V E+ +L
Sbjct: 151 TPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQE---IL 207
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR--FNEAWTKHFMCQLIDA 123
HP I+ LY++F + LY +++ + E + ++ A
Sbjct: 208 TKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAA 267
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLA--------------------A 163
LEY+H ++RDLKPEN+LL G +M++DF ++ ++ A
Sbjct: 268 LEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPA 327
Query: 164 TDNLS-----STSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE 218
D S T+SFVGT EY++PE++ D W +G +Y+ GT PF+G+N
Sbjct: 328 LDTNSYFSNFRTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNR 387
Query: 219 LAAFEKIVNLD-----YHWIYMVSQHITDLVSKILVLDPDSR----YTLPQIKNHAWFQG 269
A F I+ D YH VS L+ ++LV D R IK H +F+
Sbjct: 388 HATFSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASDIKQHPFFRH 447
Query: 270 IDW 272
I W
Sbjct: 448 IQW 450
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 134 bits (337), Expect = 4e-31
Identities = 89/302 (29%), Positives = 140/302 (45%), Gaps = 39/302 (12%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P F LG G VY ++ +G+ +A+KV SK+ +I NK K E++ +LA
Sbjct: 192 PSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQH---ILA 248
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR--FNEAWTKHFMCQLIDAL 124
NHP I+ LY++F E LY +++ +E K ++ ++ AL
Sbjct: 249 TSNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAAL 308
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGKLMITDFGV--------------------ASNLAAT 164
EY+H ++RDLKPEN+LL G +M++DF + A N A
Sbjct: 309 EYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYAL 368
Query: 165 DNLSS-----TSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENEL 219
D S T+SFVGT EY++PE++ D W +G + Y+ T PF+G+N
Sbjct: 369 DTKSCIADFRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRN 428
Query: 220 AAFEKIVNLD-----YHWIYMVSQHITDLVSKILVLDPDSRY----TLPQIKNHAWFQGI 270
F I++ D Y +S +L+ K+LV D + R +K H +F+ +
Sbjct: 429 MTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNV 488
Query: 271 DW 272
W
Sbjct: 489 QW 490
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 134 bits (337), Expect = 4e-31
Identities = 81/291 (27%), Positives = 148/291 (50%), Gaps = 24/291 (8%)
Query: 4 KRTP--QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
K+TP +DF + + +G+Y V+ +ST Q FA+K +K+++I N+++ +E++
Sbjct: 504 KKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD- 562
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
+L +P ++ ++ +F +L V+++ + + + +
Sbjct: 563 --ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETV 620
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASN--LAATDNLSS---------- 169
ALEY+H +VHRDLKP+NLL++S G + +TDFG++ ++ T NL
Sbjct: 621 LALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREF 680
Query: 170 -TSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNL 228
GT EY++PE++L+ D WA+G +LY+F G PF G+ F ++++
Sbjct: 681 LDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISD 740
Query: 229 DYHW---IYMVSQHITDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDWT 273
+ W + DL SK+L +P R + ++K H +F G+DWT
Sbjct: 741 EIVWPEGDEALPPDAQDLTSKLLHQNPLERLGTGSAYEVKQHPFFTGLDWT 791
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 134 bits (337), Expect = 4e-31
Identities = 76/272 (27%), Positives = 141/272 (50%), Gaps = 14/272 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRST-GQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
DF+ + LG G + V +S + FA+K+ K+HI+ + +++ EK + AH
Sbjct: 374 DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQG-AH 432
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+ I++LY TF DS+ LY +++ F ++ T+ + +++A Y+
Sbjct: 433 SDF--IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +++RDLKPENL+L G + DFG A + T +F GT EYV+PE++L
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG---KKTWTFCGTPEYVAPEIILN 547
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV-NLD-YHWIYMVSQHITDLVS 245
+ +D W++G ++Y+ G+PPF G + + + I+ +D + ++++ +L+
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 246 KILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
K+ +P R + I+ H WF+G +W
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNW 639
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 134 bits (337), Expect = 4e-31
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 10/218 (4%)
Query: 60 NTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQ 119
N +L HP I+K+Y + DS +LY +++F P F+ + + + +
Sbjct: 9 NEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASE 68
Query: 120 LIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEY 179
++ ALEYIH +V+RDLKPENL+LS EG + + DFG A L T + GT +Y
Sbjct: 69 IVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELR-----DRTYTICGTPDY 123
Query: 180 VSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQH 239
++PE L + N D WA+G ++Y+ G PPFRG+ ++ I+ + +
Sbjct: 124 LAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLA 183
Query: 240 ITDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
DLV K+L +D R +K+H WF+ ++W
Sbjct: 184 AKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNW 221
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 134 bits (337), Expect = 4e-31
Identities = 75/260 (28%), Positives = 127/260 (48%), Gaps = 3/260 (1%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ RLG GS++ V+ A STG+L AIK+ K+ I + E + L N
Sbjct: 21 YELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLH--N 78
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP ++K++ +Y V+++A R NE+ + + QL AL + H
Sbjct: 79 HPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHR 138
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+ HRD+KP+NLLL +G L ++DFG+++ N + GT Y +PE++ Q
Sbjct: 139 DGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLHTACGTPAYTAPEVIAQRG 198
Query: 190 SNFC-SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ +D W+ G L+ G PF N +A + KI DY + +S+ ++ K+L
Sbjct: 199 YDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRFPSWISKPARSIIYKLL 258
Query: 249 VLDPDSRYTLPQIKNHAWFQ 268
+P++R ++ + WFQ
Sbjct: 259 DPNPETRMSIEAVMGTVWFQ 278
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 134 bits (336), Expect = 6e-31
Identities = 84/268 (31%), Positives = 134/268 (49%), Gaps = 17/268 (6%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ F++ LG G++S V A D+ T +L AIK +K+ + E K + +N + +L
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEAL--EGKEGSM---ENEIAVLHKIK 74
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP I+ L + +LY ++ + E + Q++DA++Y+H
Sbjct: 75 HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHD 134
Query: 130 CKVVHRDLKPENLL---LSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+VHRDLKPENLL L + K+MI+DFG++ D S S+ GT YV+PE+L
Sbjct: 135 LGIVHRDLKPENLLYYSLDEDSKIMISDFGLSK---MEDPGSVLSTACGTPGYVAPEVLA 191
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY-----HWIYMVSQHIT 241
Q + D W++G + Y G PPF EN+ FE+I+ +Y +W +S
Sbjct: 192 QKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYW-DDISDSAK 250
Query: 242 DLVSKILVLDPDSRYTLPQIKNHAWFQG 269
D + ++ DP+ R+T Q H W G
Sbjct: 251 DFIRHLMEKDPEKRFTCEQALQHPWIAG 278
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 134 bits (336), Expect = 6e-31
Identities = 86/279 (30%), Positives = 140/279 (49%), Gaps = 15/279 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K T +DF F + LG G++ V ++ T +L+AIK+ K II+ +V + E L
Sbjct: 187 KITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQ 246
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-----FNEAWTKHFMC 118
HP + +L Y+F ++ L FV++FA + F+E + +
Sbjct: 247 RC---KHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGS 303
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
+++ AL Y+H +V+RDLK ENLLL +G + I DFG+ + + TS+F GT E
Sbjct: 304 EIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEEISFGD--KTSTFCGTPE 361
Query: 179 YVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQ 238
Y++PE+L + C D W VG ++Y+ G PF ++ FE I+ D + +SQ
Sbjct: 362 YLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQ 421
Query: 239 HITDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L++ +LV DP R +I +F+ +DW
Sbjct: 422 EARTLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDW 460
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 133 bits (334), Expect = 1e-30
Identities = 86/272 (31%), Positives = 136/272 (49%), Gaps = 15/272 (5%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ +E LG G+Y V +A +R +G++ AIK K I E + ++ E + +++ N
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRRE---IEIMSSLN 111
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II +Y F + + + ++++A R +E T+HF Q++ A+ Y H
Sbjct: 112 HPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHK 171
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
VVHRDLK EN+LL + I DFG+ SNL D T F G+ Y SPE++ N
Sbjct: 172 NGVVHRDLKLENILLDDNCNIKIADFGL-SNLYQKDKFLQT--FCGSPLYASPEIV--NG 226
Query: 190 SNFCS---DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
+ D WA+G +LY GT PF G + +I + +Y S L+
Sbjct: 227 RPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSD-ARGLIRW 285
Query: 247 ILVLDPDSRYTLPQIKNHAWFQGIDWTNKELI 278
+L+++PD R T+ I NH W ++W K +
Sbjct: 286 MLMVNPDRRATIEDIANHWW---VNWGYKSSV 314
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 133 bits (334), Expect = 1e-30
Identities = 78/272 (28%), Positives = 137/272 (49%), Gaps = 8/272 (2%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T +DF F LG G + V + R +G+LFAIK K I++ ++V+ + EK L +
Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
HP ++ L+ F E++ FV++++ F+E + ++ L+
Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV-FSEPRAIFYSACVVLGLQ 729
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
++H K+V+RDLK +NLLL +EG + I DFG+ + TS+F GT E+++PE+L
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGD--RTSTFCGTPEFLAPEVL 787
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
D W +G +LY+ G PF G++E F+ IVN + + +S ++
Sbjct: 788 TDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMR 847
Query: 246 KILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
++L +P+ R +K +F+ + W
Sbjct: 848 RLLRRNPERRLGSSERDAEDVKKQPFFRTLGW 879
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 133 bits (334), Expect = 1e-30
Identities = 78/272 (28%), Positives = 137/272 (49%), Gaps = 8/272 (2%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T +DF F LG G + V + R +G+LFAIK K I++ ++V+ + EK L +
Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
HP ++ L+ F E++ FV++++ F+E + ++ L+
Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDV-FSEPRAIFYSACVVLGLQ 729
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
++H K+V+RDLK +NLLL +EG + I DFG+ + TS+F GT E+++PE+L
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGD--RTSTFCGTPEFLAPEVL 787
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
D W +G +LY+ G PF G++E F+ IVN + + +S ++
Sbjct: 788 TDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMR 847
Query: 246 KILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
++L +P+ R +K +F+ + W
Sbjct: 848 RLLRRNPERRLGSSERDAEDVKKQPFFRTLGW 879
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 133 bits (334), Expect = 1e-30
Identities = 79/296 (26%), Positives = 153/296 (51%), Gaps = 13/296 (4%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K P D+ + + G Y V+ V R +++A+K SK+ ++ + EK +
Sbjct: 39 KTKPSDYEIVKNVAKGGYGEVF-LVRRE--KIYAMKRVSKELVLKQPHTALFMAEKEAM- 94
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+ ++ + T D E LY+++DF P E W + + +++ A
Sbjct: 95 -VDCIGSEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIVAA 153
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
L+ +H +HRDLKP+N+L+ +G + + DFG S + D + +S VGT +YVSP+
Sbjct: 154 LDELHKLGWIHRDLKPDNVLIGIDGHVKLADFG--SCIKMKDGKARSSITVGTPDYVSPD 211
Query: 184 LL--LQNKSNFCSDI--WAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQH 239
+L + + + D+ W +G ++Y+ GT PF + + + +I +++ + + VS
Sbjct: 212 VLCSVNEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITRVEFGFPFKVSPE 271
Query: 240 ITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTN-KELIWKGIWQLFGNRNHNNF 294
+T L+ L+ D R + +IK+HA+F+G+DW+ KEL + ++ G+ + ++F
Sbjct: 272 LTSLIEG-LIAAKDRRMRIEEIKSHAFFEGVDWSRLKELKPPFVPEVNGDSDTSHF 326
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 133 bits (334), Expect = 1e-30
Identities = 79/271 (29%), Positives = 142/271 (52%), Gaps = 19/271 (7%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRS-TGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
+ + F++ LG G++S V+ A +S GQ++A+K KK + K K ++E N + +L
Sbjct: 20 EKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKAL----KGKEESLE-NEIKVLR 74
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
H I++L+ T+ + + +Y V++ + E + + Q+++A+ +
Sbjct: 75 KLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGF 134
Query: 127 IHGCKVVHRDLKPENLLL---SSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
+H VVHRDLKPENLL + K+MI+DFG L+ T++ ++ GT YV+PE
Sbjct: 135 MHDNGVVHRDLKPENLLYYNQDEDSKIMISDFG----LSKTEDSGVMATACGTPGYVAPE 190
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY-----HWIYMVSQ 238
+L Q D+W++G + Y G PPF E++ F +I+ +Y +W +S
Sbjct: 191 VLQQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYW-DQISD 249
Query: 239 HITDLVSKILVLDPDSRYTLPQIKNHAWFQG 269
D ++ ++ DP++R+T +H W G
Sbjct: 250 SAKDFITHLMCCDPEARFTCQDALSHPWISG 280
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 133 bits (334), Expect = 1e-30
Identities = 88/261 (33%), Positives = 130/261 (49%), Gaps = 7/261 (2%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ LG GS+ V A TG AIK+ +++ I + + V E L L H
Sbjct: 18 NYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMH- 76
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P II+LY ++Y V+++ R E ++F Q+I +EY H
Sbjct: 77 --PHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 134
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-Q 187
VVHRDLKPENLLL S+ + I DFG+ SN+ + TS G+ Y +PE++ +
Sbjct: 135 RNMVVHRDLKPENLLLDSKCNVKIADFGL-SNIMRDGHFLKTS--CGSPNYAAPEVISGK 191
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
+ D+W+ G +LY GT PF EN F+KI Y +S DL+ ++
Sbjct: 192 LYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRM 251
Query: 248 LVLDPDSRYTLPQIKNHAWFQ 268
LV+DP R T+P+I+ H WFQ
Sbjct: 252 LVVDPMKRVTIPEIRQHPWFQ 272
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 132 bits (333), Expect = 1e-30
Identities = 80/273 (29%), Positives = 137/273 (49%), Gaps = 5/273 (1%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
S K +F F + LG GS+ V + G+ AIK K ++ ++ V+ +EK
Sbjct: 341 SSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRV 400
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
L L A +P + L TF ++L+FV++F RF + +++
Sbjct: 401 LTLAAE--NPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIM 458
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
L+++H +++RDLK +N+LL +G + I DFG+ ++ +ST F GT +Y++
Sbjct: 459 CGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRAST--FCGTPDYIA 516
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT 241
PE+L K F D W+ G +LY+ G PF G++E FE I H+ +++
Sbjct: 517 PEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESK 576
Query: 242 DLVSKILVLDPDSRYTLP-QIKNHAWFQGIDWT 273
D++ K+ +P R + IK H +F+ I+WT
Sbjct: 577 DILEKLFEREPTKRLGMTGNIKIHPFFKTINWT 609
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 132 bits (333), Expect = 1e-30
Identities = 79/273 (28%), Positives = 135/273 (48%), Gaps = 9/273 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F LG GS+ V A + T +L+AIK+ K +I ++ V+ +EK L LL
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALL--D 395
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P + +L+ F + LYFV+++ +F E + ++ L ++H
Sbjct: 396 KPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLH 455
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLK +N++L SEG + I DFG+ D ++ T +F GT +Y++PE++
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKE-HMMDGVT-TRTFCGTPDYIAPEIIAYQ 513
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D WA G +LY+ G PPF GE+E F+ I+ + + +S+ + ++
Sbjct: 514 PYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLM 573
Query: 249 VLDPDSRYTL-----PQIKNHAWFQGIDWTNKE 276
P R ++ HA+F+ IDW E
Sbjct: 574 TKHPAKRLGCGPEGERDVREHAFFRRIDWEKLE 606
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 132 bits (333), Expect = 1e-30
Identities = 79/278 (28%), Positives = 134/278 (47%), Gaps = 14/278 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENK-VKYVTIEK 59
K P+DF K+ LG G Y V+ K R + FA+KV K I++ K + E+
Sbjct: 71 KLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAER 130
Query: 60 NTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQ 119
N L + HP I++L Y F LY +L++ F E T ++ +
Sbjct: 131 NILEAV---KHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSE 187
Query: 120 LIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEY 179
+I AL ++H +++RDLKPEN+LL ++G + +TDFG+ ++ T F GT EY
Sbjct: 188 IILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVTHT--FCGTIEY 245
Query: 180 VSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQH 239
++PE+L ++ D W++G +++ G PPF EN E I+ + ++
Sbjct: 246 MAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPE 305
Query: 240 ITDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
DLV +++ R ++ H +F+ ++W
Sbjct: 306 ARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNW 343
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 132 bits (331), Expect = 2e-30
Identities = 90/317 (28%), Positives = 163/317 (51%), Gaps = 15/317 (4%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P+DF+ +G G++ VY T +++A+K SKK I+ + +V + E+N L +
Sbjct: 299 PEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTS 358
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
P I+ L ++F + +LY + D+ RF E K ++ +L+ ALE+
Sbjct: 359 LDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEH 418
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVA-SNLAATDNLSSTSSFVGTAEYVSPELL 185
+H +++RDLKPEN+LL ++G + + DFG++ +NL+A ++T++F GT EY++PE+L
Sbjct: 419 LHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSAN---ATTNTFCGTTEYLAPEVL 475
Query: 186 LQNKSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY-MVSQHITDL 243
L++K D W++G ++++ G PF + + I + ++S
Sbjct: 476 LEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSF 535
Query: 244 VSKILVLDPDSRY----TLPQIKNHAWFQGIDWTNKELIWKGIWQLFGNRNHNNFNGPSM 299
V +L +P+ R ++K H +F I+W +L+ K Q N N S
Sbjct: 536 VRGLLNRNPNHRLGAVADTTELKEHPFFADINW---DLLSKKKVQPPFKPNVQNDLDVSN 592
Query: 300 MNKQLHVIDTTIKNIPI 316
+K+ +T +KNI I
Sbjct: 593 FDKEF--TNTNVKNINI 607
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 132 bits (331), Expect = 2e-30
Identities = 80/270 (29%), Positives = 134/270 (49%), Gaps = 8/270 (2%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
QDF LG G + V + TG+ +AIK K+ ++S ++++ + EK L +
Sbjct: 557 QDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGC 616
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
HP ++ L F S + FV +F P F E + ++ ++ L+++
Sbjct: 617 TGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHEDV-FPEPQARFYVACVVLGLQFL 675
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H K+++RDLK +NLLL ++G L I DFG+ + TS+F GT E+++PE+L Q
Sbjct: 676 HEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGD--RTSTFCGTPEFLAPEVLTQ 733
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
D WA+G +LY+ G PF G+ E F+ IVN+D + +S + + K+
Sbjct: 734 EAYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKL 793
Query: 248 LVLDPDSR-----YTLPQIKNHAWFQGIDW 272
L P+ R +IK +F+ +W
Sbjct: 794 LQKCPEKRLGAGEQDAEEIKVQPFFRTTNW 823
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 132 bits (331), Expect = 2e-30
Identities = 78/273 (28%), Positives = 138/273 (49%), Gaps = 11/273 (4%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T +F + + LG G++ V +++TG+ +A+K+ K+ I+++++V + E L
Sbjct: 146 TMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ-- 203
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
+ HP + L Y+F + L FV+++A F+E + + +++ AL+
Sbjct: 204 -NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALD 262
Query: 126 YIHGCK-VVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
Y+H K VV+RDLK ENL+L +G + ITDFG+ + ++ +F GT EY++PE+
Sbjct: 263 YLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE--GIKDGATMKTFCGTPEYLAPEV 320
Query: 185 LLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLV 244
L N D W +G ++Y+ G PF ++ FE I+ + + + L+
Sbjct: 321 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLL 380
Query: 245 SKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
S +L DP R +I H +F GI W
Sbjct: 381 SGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVW 413
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 132 bits (331), Expect = 2e-30
Identities = 81/266 (30%), Positives = 134/266 (49%), Gaps = 15/266 (5%)
Query: 16 LGHGSYSTV-YKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGII 74
LG G + V V+ + FA+K KKHI+ + +++ E+N ++ + I+
Sbjct: 432 LGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERN---IMMETSTDWIV 488
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVH 134
KLY TF D + +Y +L+ F++ + ++ +++ LEY+H +V+
Sbjct: 489 KLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVY 548
Query: 135 RDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCS 194
RDLKPEN LL++ G L + DFG A LA+ T +F GT EYVSPE++L + +
Sbjct: 549 RDLKPENCLLANTGYLKLVDFGFAKKLASG---RKTWTFCGTPEYVSPEIILNKGHDQAA 605
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIV-NLDYHWI--YMVSQHITDLVSKILVLD 251
D WA+G + + G PPF+ + + + I+ +D I + + T LV K+ +
Sbjct: 606 DYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDN 665
Query: 252 PDSRY-----TLPQIKNHAWFQGIDW 272
P R + I+ H WF G DW
Sbjct: 666 PGERLGSGSGGVNDIRKHRWFMGFDW 691
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 132 bits (331), Expect = 2e-30
Identities = 81/266 (30%), Positives = 134/266 (49%), Gaps = 15/266 (5%)
Query: 16 LGHGSYSTV-YKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGII 74
LG G + V V+ + FA+K KKHI+ + +++ E+N ++ + I+
Sbjct: 475 LGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERN---IMMETSTDWIV 531
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVH 134
KLY TF D + +Y +L+ F++ + ++ +++ LEY+H +V+
Sbjct: 532 KLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVY 591
Query: 135 RDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCS 194
RDLKPEN LL++ G L + DFG A LA+ T +F GT EYVSPE++L + +
Sbjct: 592 RDLKPENCLLANTGYLKLVDFGFAKKLASG---RKTWTFCGTPEYVSPEIILNKGHDQAA 648
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIV-NLDYHWI--YMVSQHITDLVSKILVLD 251
D WA+G + + G PPF+ + + + I+ +D I + + T LV K+ +
Sbjct: 649 DYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDN 708
Query: 252 PDSRY-----TLPQIKNHAWFQGIDW 272
P R + I+ H WF G DW
Sbjct: 709 PGERLGSGSGGVNDIRKHRWFMGFDW 734
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 132 bits (331), Expect = 2e-30
Identities = 86/261 (32%), Positives = 130/261 (48%), Gaps = 7/261 (2%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ + LG GS+ V A TG AIK+ +++ I + + V E L L H
Sbjct: 19 NYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMH- 77
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P II+ Y + ++Y V+++ R E ++F Q+I +EY H
Sbjct: 78 --PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 135
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-Q 187
VVHRDLKPENLLL S + I DFG+ SN+ + TS G+ Y +PE++ +
Sbjct: 136 RNMVVHRDLKPENLLLDSRCNIKIADFGL-SNVMRDGHFLKTS--CGSPNYAAPEVISGK 192
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
+ D+W+ G +LY GT PF EN F+KI Y +S DL+ ++
Sbjct: 193 LYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRM 252
Query: 248 LVLDPDSRYTLPQIKNHAWFQ 268
L++DP R T+P+I+ H WFQ
Sbjct: 253 LIVDPVKRITIPEIRQHRWFQ 273
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 131 bits (329), Expect = 4e-30
Identities = 81/283 (28%), Positives = 137/283 (47%), Gaps = 15/283 (5%)
Query: 7 PQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENK-VKYVTIEKNTL 62
P F LG G Y V+ K + G+++A+KV K I+ K + E+N L
Sbjct: 77 PHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNIL 136
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+ HP I++L Y F LY +L+ F E ++ ++
Sbjct: 137 ESV---KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL 193
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL ++H +++RDLKPEN++LSS+G + +TDFG+ + + T +F GT EY++P
Sbjct: 194 ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKE--SIHEGAVTHTFCGTIEYMAP 251
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
E+L+++ N D W++G ++Y G+PPF EN +KI+ ++ D
Sbjct: 252 EILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARD 311
Query: 243 LVSKILVLDPDSRY-----TLPQIKNHAWFQGIDWTNKELIWK 280
LV K L +P R ++ H +F+ ++W + L W+
Sbjct: 312 LVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDL-LAWR 353
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 131 bits (329), Expect = 4e-30
Identities = 77/276 (27%), Positives = 140/276 (49%), Gaps = 17/276 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + +G G++ V+ T ++A+K+ +K +I + E++ ++AH
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERD---IMAHA 123
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
N I++L Y F D +LY V+++ P +E WT+ + ++++AL +H
Sbjct: 124 NSEWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSY-EVSEKWTRFYTAEIVEALAALH 182
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+HRD+KP+N+L+S G + + DFG + A + + S+ VGT +Y+SPE +L+N
Sbjct: 183 SMGYIHRDVKPDNMLISISGHIKLADFGTCVKMNA-NGVVRCSTAVGTPDYISPE-VLRN 240
Query: 189 KSNFCS-----DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN----LDYHWIYMVSQH 239
+ D W+VG +Y+ G PF E ++ + I+N L + ++S
Sbjct: 241 QGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQ 300
Query: 240 ITDLVSKILVLDPD--SRYTLPQIKNHAWFQGIDWT 273
D++ K L PD R ++ I+NH +F +WT
Sbjct: 301 AKDIIKKFLSAAPDRLGRNSVDDIRNHKFFVNDEWT 336
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 131 bits (329), Expect = 4e-30
Identities = 80/257 (31%), Positives = 136/257 (52%), Gaps = 11/257 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LGHG+++ VY A + TG+ A+KV K+ ++ KV V K ++++ HP I++
Sbjct: 30 LGHGTFAKVYHARNIQTGKSVAMKVVGKEKVV---KVGMVDQIKREISVMRMVKHPNIVE 86
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +YF ++ R E + + QLI A+++ H V HR
Sbjct: 87 LHEVMASKSKIYFAMELV-RGGELFAKVAKGRLREDVARVYFQQLISAVDFCHSRGVYHR 145
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTS---SFVGTAEYVSPELLLQNKSNF 192
DLKPENLLL EG L +TDFG++ A T++L + GT YV+PE++L+ +
Sbjct: 146 DLKPENLLLDEEGNLKVTDFGLS---AFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDG 202
Query: 193 C-SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLD 251
+D+W+ G +L+ G PF+ +N + + KI D+ +S LV+K+L +
Sbjct: 203 AKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRLVTKLLDPN 262
Query: 252 PDSRYTLPQIKNHAWFQ 268
P++R T+ ++ + WF+
Sbjct: 263 PNTRITIEKVMDSPWFK 279
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 131 bits (329), Expect = 4e-30
Identities = 83/265 (31%), Positives = 135/265 (50%), Gaps = 18/265 (6%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISEN-KVKYVTIEKNTLNLLAHGNHPGII 74
LG G+++ VY + STG AIKV K H+ ++ + E + LL HP ++
Sbjct: 21 LGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLL---RHPNVV 77
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVH 134
+L + ++FV+++ + E + + QLI A+++ H V H
Sbjct: 78 ELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRGVFH 137
Query: 135 RDLKPENLLLSSEGKLMITDFGVASNL---------AATDNLSSTSSFVGTAEYVSPELL 185
RD+KPENLLL EG L +TDFG+++ + ++D+L T GT YV+PE +
Sbjct: 138 RDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTR--CGTPAYVAPE-V 194
Query: 186 LQNK--SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
L+NK +DIW+ G +LY G PF EN + + KI + + S +L
Sbjct: 195 LRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLESKEL 254
Query: 244 VSKILVLDPDSRYTLPQIKNHAWFQ 268
+S++LV DP+ R ++ +IK WF+
Sbjct: 255 LSRLLVPDPEQRISMSEIKMIPWFR 279
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 131 bits (329), Expect = 4e-30
Identities = 73/252 (28%), Positives = 134/252 (52%), Gaps = 14/252 (5%)
Query: 34 QLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFA 93
Q A+K+ K ++ ++++++V EKN + + P I++LY T+ + + +YF+++
Sbjct: 716 QALALKIIKKIEVVKQDQIEHVYNEKNVM--IKCRQSPFIVQLYRTYRNDKYVYFLMEAC 773
Query: 94 PXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMIT 153
F+E K +++A +Y+H ++RDLKPENL+L ++G +
Sbjct: 774 MGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLV 833
Query: 154 DFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPF 213
DFG A + + T++F GT EYV+PE++L + D WA+G ++Y+ G PF
Sbjct: 834 DFGFAKFVRQNEK---TNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPF 890
Query: 214 RGENELAAFEKIVNLDYHWIYMVS------QHITDLVSKILVLD--PDSRYTLPQIKNHA 265
RG N++ +++I++ I+M S QH+ + K L + R + IK H+
Sbjct: 891 RGVNQIKIYQQILS-GIDVIHMPSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHS 949
Query: 266 WFQGIDWTNKEL 277
WF+ +DW +L
Sbjct: 950 WFESLDWQRLKL 961
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 130 bits (326), Expect = 8e-30
Identities = 78/276 (28%), Positives = 134/276 (48%), Gaps = 15/276 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F LG GS+ V + + T +L+A+K+ K +I ++ V+ +EK L L G
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLAL--PG 398
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P + +L+ F + LYFV+++ RF E + ++ L ++
Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNL---SSTSSFVGTAEYVSPELL 185
+++RDLK +N++L SEG + I DFG+ +N+ +T +F GT +Y++PE++
Sbjct: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCK-----ENIWDGVTTKTFCGTPDYIAPEII 513
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
D WA G +LY+ G PF GE+E F+ I+ + + +S+ +
Sbjct: 514 AYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICK 573
Query: 246 KILVLDPDSRYTL-----PQIKNHAWFQGIDWTNKE 276
++ P R IK HA+F+ IDW E
Sbjct: 574 GLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLE 609
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 130 bits (326), Expect = 8e-30
Identities = 78/276 (28%), Positives = 134/276 (48%), Gaps = 15/276 (5%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F LG GS+ V + + T +L+A+K+ K +I ++ V+ +EK L L G
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLAL--PG 398
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P + +L+ F + LYFV+++ RF E + ++ L ++
Sbjct: 399 KPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQ 458
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNL---SSTSSFVGTAEYVSPELL 185
+++RDLK +N++L SEG + I DFG+ +N+ +T +F GT +Y++PE++
Sbjct: 459 SKGIIYRDLKLDNVMLDSEGHIKIADFGMCK-----ENIWDGVTTKTFCGTPDYIAPEII 513
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
D WA G +LY+ G PF GE+E F+ I+ + + +S+ +
Sbjct: 514 AYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICK 573
Query: 246 KILVLDPDSRYTL-----PQIKNHAWFQGIDWTNKE 276
++ P R IK HA+F+ IDW E
Sbjct: 574 GLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLE 609
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 130 bits (326), Expect = 8e-30
Identities = 87/324 (26%), Positives = 144/324 (43%), Gaps = 59/324 (18%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K + DF +G G++ V +R +G ++A+K K ++ +V++V E+N
Sbjct: 88 KISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMVMRGQVEHVRAERN--- 144
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
LLA I+KLYY+F D E LY ++++ P E + ++ Q + A
Sbjct: 145 LLAEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLREDVARFYIAQSVLA 204
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAA-------------------- 163
+E IH +HRD+KP+NLLL +G + ++DFG+ L
Sbjct: 205 IESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQENRATDDETMSEP 264
Query: 164 ---------TDNLSS------------------TSSFVGTAEYVSPELLLQNKSNFCSDI 196
TDN S S VGT +Y++PE+LL+ D
Sbjct: 265 MDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYIAPEVLLKKGYGMECDW 324
Query: 197 WAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY----MVSQHITDLVSKILVLDP 252
W++G ++Y+ G PPF ++ ++ KIV+ H + S DL+ ++L +
Sbjct: 325 WSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKFSSEAKDLICRLL-CNV 383
Query: 253 DSRY----TLPQIKNHAWFQGIDW 272
D R QIK+H WF+ + W
Sbjct: 384 DHRLGTGGGAQQIKDHPWFKDVVW 407
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 130 bits (326), Expect = 8e-30
Identities = 78/273 (28%), Positives = 134/273 (48%), Gaps = 9/273 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF+F + LG GS+ V A + + +L+AIK+ K II ++ V+ IEK L L
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLAL--GE 406
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P +++L+ F + L+FV+++ +F E + ++ L ++H
Sbjct: 407 KPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLH 466
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLK +N+LL ++G + I DFG+ D +T +F GT +Y++PE++L
Sbjct: 467 TKGILYRDLKLDNVLLDADGHVKIADFGMCKENIVGDK--TTKTFCGTPDYIAPEIILYQ 524
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D WA G +LY+ G PPF GE+E F I + + + +S+ + L
Sbjct: 525 PYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFL 584
Query: 249 VLDPDSRYTL-----PQIKNHAWFQGIDWTNKE 276
P+ R ++ H +F+ IDW E
Sbjct: 585 TKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIE 617
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 129 bits (325), Expect = 1e-29
Identities = 81/283 (28%), Positives = 142/283 (49%), Gaps = 17/283 (6%)
Query: 4 KRTPQDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVK-YVTIEK 59
K + ++F + LG G+Y V+ KA G+L+A+KV K ++ K + + E+
Sbjct: 27 KVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86
Query: 60 NTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQ 119
+ L L+ P ++ L+Y F L+ +LD+ F EA + + +
Sbjct: 87 SVLELVRQA--PFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGE 144
Query: 120 LIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEY 179
++ ALE++H +++RDLK EN+LL SEG +++TDFG++ T+ T SF GT EY
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEF-LTEEKERTFSFCGTIEY 203
Query: 180 VSPELLLQNKSN-FCSDIWAVGCMLYQFTQGTPPFRGENE----LAAFEKIVNLDYHWIY 234
++PE++ + D W++G +L++ G PF E E +I+ +
Sbjct: 204 MAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPP 263
Query: 235 MVSQHITDLVSKILVLDPDSR-----YTLPQIKNHAWFQGIDW 272
+ DL+ ++L DP R +++NH +FQG+DW
Sbjct: 264 RIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDW 306
Score = 107 bits (266), Expect = 7e-23
Identities = 96/372 (25%), Positives = 160/372 (42%), Gaps = 42/372 (11%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH----GNHP 71
LG GS+S + R +GQ FA+K+ S++ +E NT +A +HP
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRR------------LEANTQREVAALRLCQSHP 464
Query: 72 GIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG-C 130
++ L+ HD + Y VL+ F+E+ + L+ A+ ++H
Sbjct: 465 NVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEA 524
Query: 131 KVVHRDLKPENLLLSSE---GKLMITDFGVASNLAATDNLS-STSSFVGTAEYVSPELLL 186
VVHRDLKPEN+L + + + I DFG A + + T F T +Y +PELL
Sbjct: 525 GVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCF--TLQYAAPELLA 582
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFR------GENELAAF-----EKIVNLDYHWIYM 235
Q + D+W++G +LY G PF+ G+++ A E +LD
Sbjct: 583 QQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQG 642
Query: 236 VSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ-GIDWTNKELIWKGIWQLFGNRNHNNF 294
VS+ +LV +L +DP R L ++ +W Q G ++ L + + G +
Sbjct: 643 VSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGL 702
Query: 295 NGPSM---MNKQLHVIDTTIKNIPIQPRKRKPMKVTQTTSSIVEWRKTLGLSPVSGSVGP 351
N M K+ +++N P+ KR+ K+ T+S +P V
Sbjct: 703 NATFMAFNRGKREGFFLKSVENAPL--AKRRKQKLRSATAS--RRGSPAPANPGRAPVAS 758
Query: 352 NGLPKQMKSHVP 363
G P++ +P
Sbjct: 759 KGAPRRANGPLP 770
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 129 bits (325), Expect = 1e-29
Identities = 68/232 (29%), Positives = 123/232 (52%), Gaps = 16/232 (6%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
QD +G G++ V+ +++ FA+KV S +I + ++V EK+ L ++H
Sbjct: 47 QDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSH 106
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
P +I+L++T+H+ LY ++++ P F+ + ++I A+EY+
Sbjct: 107 ---PFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYL 163
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H ++V+RDLKPEN+LL +G + +TDFG A L + T + GT EY++PE++
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-----VDRTWTLCGTPEYLAPEVIQS 218
Query: 188 NKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV--------NLDYH 231
D WA+G ++++ G PPF +N ++KI+ +LD+H
Sbjct: 219 KGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFH 270
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 129 bits (325), Expect = 1e-29
Identities = 80/271 (29%), Positives = 131/271 (47%), Gaps = 11/271 (4%)
Query: 5 RTPQD------FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIE 58
RTPQ + + LGHGS++ VY A + +G+ AIKV K+ I+ ++
Sbjct: 46 RTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHI--- 102
Query: 59 KNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMC 118
K +++L HP I+ L +Y V+++ R E + +
Sbjct: 103 KREISILRRVRHPYIVHLLEVMATKTKIYIVMEYV-RGGELYNTVARGRLREGTARRYFQ 161
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
QLI ++ + H V HRDLK ENLLL +G + ++DFG++ +F GT
Sbjct: 162 QLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGICQTFCGTPA 221
Query: 179 YVSPELLLQNKSNFC-SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVS 237
Y++PE+L + +DIW+ G +L+ G PF +N L + KI + S
Sbjct: 222 YLAPEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFS 281
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
+ LV+++L +PD+R T+P+I H WF+
Sbjct: 282 PELARLVTRMLDTNPDTRITIPEIMKHRWFK 312
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 129 bits (324), Expect = 1e-29
Identities = 80/289 (27%), Positives = 141/289 (48%), Gaps = 22/289 (7%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
RK DF + + +G+Y VY R T Q FAIK +K+++I N+++ V +E++
Sbjct: 190 RKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERD-- 247
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
+L +P ++ ++ +F +L V+++ + + + +
Sbjct: 248 -ILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVL 306
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFG--------VASNLAATDNLSSTSSFV 174
ALEY+H +VHRDLKP+NLL++S G + +TDFG +A+NL F+
Sbjct: 307 ALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFI 366
Query: 175 -----GTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLD 229
GT EY++PE++ + D WA+G +LY+F G PF G+ F ++V+ +
Sbjct: 367 DKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDE 426
Query: 230 YHW---IYMVSQHITDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDW 272
W + DL++++L P R ++K H +F +DW
Sbjct: 427 IMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDW 475
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 129 bits (324), Expect = 1e-29
Identities = 79/269 (29%), Positives = 127/269 (46%), Gaps = 14/269 (5%)
Query: 5 RTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNL 64
R + K +G GS+S V + R+T Q +AIK+ K+ + ++ L +
Sbjct: 93 RVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGRE------VCESELRV 146
Query: 65 LAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDAL 124
L H II+L F E +Y V++ A F E + ++D +
Sbjct: 147 LRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGV 206
Query: 125 EYIHGCKVVHRDLKPENLLL---SSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
Y+H + HRDLKPENLL ++ K++ITDFG+AS D+ ++ GT EY++
Sbjct: 207 RYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTT-CGTPEYIA 265
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWI----YMVS 237
PE+L++ D+WA+G + Y GT PF +N + +I+ Y + VS
Sbjct: 266 PEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVS 325
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAW 266
D + ++L +DP +R T Q H W
Sbjct: 326 NLAKDFIDRLLTVDPGARMTALQALRHPW 354
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 129 bits (324), Expect = 1e-29
Identities = 78/256 (30%), Positives = 131/256 (50%), Gaps = 9/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G++ VY + +TG+ AIK+ +K + E ++ + E + + L+ HP I++
Sbjct: 21 LGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLV---RHPNIVE 77
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L ++F++++ ++ K+F QLI A+++ H V HR
Sbjct: 78 LKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSARKYFQ-QLISAVDFCHSRGVSHR 136
Query: 136 DLKPENLLLSSEGKLMITDFGVAS--NLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
DLKPENLL+ G L ++DFG+++ D L T GT YV+PE+L + +
Sbjct: 137 DLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQC--GTPAYVAPEVLRKKGYDGA 194
Query: 194 S-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
DIW+ G +LY G PF+ EN + + KI ++ + S L+SK+LV+DP
Sbjct: 195 KGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVDP 254
Query: 253 DSRYTLPQIKNHAWFQ 268
+ R ++P I WF+
Sbjct: 255 NKRISIPAIMRTPWFR 270
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 129 bits (324), Expect = 1e-29
Identities = 79/308 (25%), Positives = 145/308 (46%), Gaps = 46/308 (14%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF + +G G++ V + TG ++A+KV K ++ + +V +V E++ +L
Sbjct: 91 EDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERD---VLVE 147
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+H ++K+YY+F D NLY +++F P +E T+ ++ + A++ I
Sbjct: 148 ADHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSI 207
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLA---ATDNLSSTS------------- 171
H +HRD+KP+NLLL + G L ++DFG+ + L TD S
Sbjct: 208 HKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCAS 267
Query: 172 --------------------SFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTP 211
S VGT +Y++PE+ LQ D W++G ++Y+ G P
Sbjct: 268 PMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYP 327
Query: 212 PFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILV---LDPD----SRYTLPQIKNH 264
PF +N + K++N I+ I++ + ++ + D S+ L +K+
Sbjct: 328 PFCSDNPQDTYRKVMNWRETLIFPPEIPISEEAKETIINFCCEADRRLGSQRGLEDLKSV 387
Query: 265 AWFQGIDW 272
+F+G+DW
Sbjct: 388 PFFRGVDW 395
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 129 bits (323), Expect = 2e-29
Identities = 77/255 (30%), Positives = 128/255 (50%), Gaps = 8/255 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ V A + G AIKV K+ ++ + + E +T+ L+ HP +I+
Sbjct: 37 LGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLI---KHPNVIR 93
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
++ +YFVL+F R E + + QLI+A++Y H V HR
Sbjct: 94 MFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHR 153
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK--SNFC 193
DLKPENLLL + G L ++DFG+++ D L T+ GT YV+PE ++ NK
Sbjct: 154 DLKPENLLLDANGALKVSDFGLSALPQQEDGLLHTT--CGTPNYVAPE-VINNKGYDGAK 210
Query: 194 SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPD 253
+D+W+ G +L+ G PF N + ++KI ++ S L+ +IL +P
Sbjct: 211 ADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASAKKLIKRILDPNPA 270
Query: 254 SRYTLPQIKNHAWFQ 268
+R T ++ + WF+
Sbjct: 271 TRITFAEVIENEWFK 285
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 128 bits (322), Expect = 2e-29
Identities = 91/285 (31%), Positives = 144/285 (49%), Gaps = 17/285 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKH--IISENKVKYVTIEKNT 61
K ++ + LG G+ V A +R T + AIK+ SK+ I S + +
Sbjct: 214 KALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETE 273
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
+ +L NHP IIK+ F D+E+ Y VL+ R EA K + Q++
Sbjct: 274 IEILKKLNHPCIIKIK-NFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQML 332
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAE 178
A++Y+H ++HRDLKPEN+LLSS+ + + ITDFG + L T S + GT
Sbjct: 333 LAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGET---SLMRTLCGTPT 389
Query: 179 YVSPELLLQNKS---NFCSDIWAVGCMLYQFTQGTPPF-RGENELAAFEKIVNLDYHWI- 233
Y++PE+L+ + N D W++G +L+ G PPF +++ ++I + Y++I
Sbjct: 390 YLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIP 449
Query: 234 ---YMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNK 275
VS+ DLV K+LV+DP +R+T + H W Q D K
Sbjct: 450 EVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRK 494
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 128 bits (322), Expect = 2e-29
Identities = 80/272 (29%), Positives = 133/272 (48%), Gaps = 10/272 (3%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T DF F + LG G++ V ++S+ +L+AIK+ K+ ++ ++V + E L
Sbjct: 176 TMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYAC 235
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
H P + L Y+F ++ FV++FA F+EA T+ + ++I AL
Sbjct: 236 VH---PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALG 292
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
Y+H +V+RD+K ENLLL +G + ITDFG+ + TS+F GT EY++PE++
Sbjct: 293 YLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGD--KTSTFCGTPEYLAPEVI 350
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
+ D W VG ++Y+ G PF + FE I D + +S L+S
Sbjct: 351 EDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTLLS 410
Query: 246 KILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
+L P R ++ +F+ +DW
Sbjct: 411 GLLERVPAKRLGAGPDDAREVSRAEFFKDVDW 442
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 128 bits (322), Expect = 2e-29
Identities = 80/272 (29%), Positives = 133/272 (48%), Gaps = 10/272 (3%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T DF F + LG G++ V ++S+ +L+AIK+ K+ ++ ++V + E L
Sbjct: 176 TMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYAC 235
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
H P + L Y+F ++ FV++FA F+EA T+ + ++I AL
Sbjct: 236 VH---PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALG 292
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
Y+H +V+RD+K ENLLL +G + ITDFG+ + TS+F GT EY++PE++
Sbjct: 293 YLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGD--KTSTFCGTPEYLAPEVI 350
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
+ D W VG ++Y+ G PF + FE I D + +S L+S
Sbjct: 351 EDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTLLS 410
Query: 246 KILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
+L P R ++ +F+ +DW
Sbjct: 411 GLLERVPAKRLGAGPDDAREVSRAEFFKDVDW 442
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 128 bits (322), Expect = 2e-29
Identities = 82/256 (32%), Positives = 128/256 (49%), Gaps = 8/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ VY + G+ AIKV +K ++ + K ++++ HP I++
Sbjct: 18 LGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQI--KREISIMKLVRHPNIVE 75
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L ++FV++F +A ++F QLI A++Y H V HR
Sbjct: 76 LKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARRYFQ-QLISAVDYCHSRGVSHR 134
Query: 136 DLKPENLLLSSEGKLMITDFGVAS--NLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
DLKPENLLL G L I+DFG+++ D L T GT YV+PE+L + +
Sbjct: 135 DLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQC--GTPAYVAPEVLKKKGYDGA 192
Query: 194 -SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
+DIW+ G +LY G PF+ EN + + KI D+ + S L+SK+LV+DP
Sbjct: 193 KADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWFSPEARRLISKLLVVDP 252
Query: 253 DSRYTLPQIKNHAWFQ 268
D R ++P I W +
Sbjct: 253 DRRISIPAIMRTPWLR 268
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 128 bits (321), Expect = 3e-29
Identities = 81/329 (24%), Positives = 150/329 (44%), Gaps = 65/329 (19%)
Query: 1 MSRKRTP---QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTI 57
+ +KRT F +LG G Y +V+ A R+T +L A+K+ K + N+VK++
Sbjct: 150 LRKKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILN 209
Query: 58 EKNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFM 117
E++ +L + N ++KLYY F D E +Y +++ P +E T+ ++
Sbjct: 210 ERD---ILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYL 266
Query: 118 CQLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATD------------ 165
+++ A+ +H +HRDLKPEN L+ +G + ++DFG+++ + ++
Sbjct: 267 AEMVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSA 326
Query: 166 -----------------------NLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCM 202
N + +S VG+ EY++PE++ K + D W++GC+
Sbjct: 327 VNPQRPYLTQKQRRNIYKALLEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCI 386
Query: 203 LYQFTQGTPPFRGENELAAFEKIVNLDYHWIYM------------------VSQHITDLV 244
Y+ G PPF G + + Y+W M VS +
Sbjct: 387 CYECLVGYPPFSGSTLQETWTNL----YYWREMLQRPSKNENGIYDKKARSVSDEAWSFI 442
Query: 245 SKILVLDPDSRY-TLPQIKNHAWFQGIDW 272
+K L +P SR+ + +I+ H +F+ + W
Sbjct: 443 TKCLT-EPTSRFQSTIEIQKHPFFKRLHW 470
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 128 bits (321), Expect = 3e-29
Identities = 80/277 (28%), Positives = 133/277 (47%), Gaps = 23/277 (8%)
Query: 9 DFSFKERLGHGSYSTV--YKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
D LG G + V KA + +FA+K K+HI+ + +++ E++ ++
Sbjct: 456 DLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERH---IML 512
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
P I +LY TF D + +Y +L+ F + + + ++ A EY
Sbjct: 513 SSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEY 572
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H +++RDLKPENL+L G + I DFG A + + S T +F GT EYV+PE++L
Sbjct: 573 LHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTS---SKTWTFCGTPEYVAPEIIL 629
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVS--QHIT--- 241
+ D WA+G ++++ GTPPF + + + NL I M++ +HI+
Sbjct: 630 NKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTY----NLILKGIDMIAFPKHISRWA 685
Query: 242 -DLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
L+ ++ P R + IK H WF G DW
Sbjct: 686 VQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDW 722
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 128 bits (321), Expect = 3e-29
Identities = 81/287 (28%), Positives = 140/287 (48%), Gaps = 37/287 (12%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF K +G G + V+ V+R T ++A+K KK +++ ++VK ++++
Sbjct: 112 DFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKI-KKSVVTTSQVK------EERDIMSIR 164
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
N +I L Y F D++NLY V+++ P F+E + ++ +L AL +H
Sbjct: 165 NSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVALHTLH 224
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL---- 184
VHRD+KPEN+L+ G + + DFG A+ L ++ S S VGT +Y++PEL
Sbjct: 225 EMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLSLSP-VGTPDYIAPELLQTI 283
Query: 185 ----LLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
L ++ + D W++G + Y+ T PF +N + KI++ + H+
Sbjct: 284 STYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILS------HCEESHL 337
Query: 241 TDLVS---------------KILVLDPDSRYTLPQIKNHAWFQGIDW 272
+L+S + LV +P R + +IKNH +F I W
Sbjct: 338 KELISFPADLKVSVNYRNLIESLVTNPSKRLSYERIKNHPFFSEIPW 384
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 127 bits (320), Expect = 4e-29
Identities = 84/270 (31%), Positives = 132/270 (48%), Gaps = 10/270 (3%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K +D+ LG G ++ ++ D S G++FA K +K I SE K + E +
Sbjct: 76 KTRGKDYHRGHFLGEGGFARCFQIKDDS-GEIFAAKTVAKASIKSEKTRKKLLSE---IQ 131
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+ +HP I++ F D N+Y +L+ P E + F Q+ A
Sbjct: 132 IHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGA 191
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
++Y+H +V+HRDLK N+ S L I DFG+A+ LA T GT Y++PE
Sbjct: 192 IKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYT--ICGTPNYIAPE 249
Query: 184 LLLQNKS--NFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHW--IYMVSQH 239
+L+ S +F DIW++G MLY G PPF+ + +E+I D+ + +S
Sbjct: 250 VLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDE 309
Query: 240 ITDLVSKILVLDPDSRYTLPQIKNHAWFQG 269
L+ IL LDP R +L +I ++ WF+G
Sbjct: 310 GKILIRDILSLDPIERPSLTEIMDYVWFRG 339
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 127 bits (320), Expect = 4e-29
Identities = 76/237 (32%), Positives = 122/237 (51%), Gaps = 8/237 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G ++ Y+ ++STG+LFA KV K +I + + + E L H N ++K
Sbjct: 42 LGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRN---VVK 98
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
LY+ F D N+Y L+ P E ++F Q+++ + Y+H K+VHR
Sbjct: 99 LYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLKIVHR 158
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLK NL L+ E ++ I DFG+A+ DN + GT Y++PE+L + +F D
Sbjct: 159 DLKLGNLFLNDELQVKIGDFGLAT---TCDNDERKKTLCGTPNYIAPEVLNKIGHSFEVD 215
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
+WA+GC+LY G PPF ++ + +I N +Y S + L+ ++LDP
Sbjct: 216 LWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQLIR--VLLDP 270
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 127 bits (320), Expect = 4e-29
Identities = 89/287 (31%), Positives = 142/287 (49%), Gaps = 25/287 (8%)
Query: 1 MSRKRTP--QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIE 58
+S K P Q FS +G G++ V +R T + FA+K +K+ I + V E
Sbjct: 17 VSGKSAPCLQHFSVIRSIGRGAFGKVCIVQERKTKKYFALKYMNKRRCIEKGVAANVIRE 76
Query: 59 KNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMC 118
L LL+ +HP I+ L+YTF D + +Y V D +F E K ++C
Sbjct: 77 ---LTLLSKMSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLYLC 133
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
++ A+EY+H K+VHRD+KPEN+LL +G +TD +A+ L D L+ +S+ GT
Sbjct: 134 EICLAVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLATQL-EDDQLA--TSYSGTRP 190
Query: 179 YVSPEL---LLQNKSNFCS--DIWAVGCMLYQFTQGTPPF------RGENELAAF-EKIV 226
Y++PE+ L+ + + S D WA+G Y+ +G PF + E AF E +
Sbjct: 191 YMAPEIYATYLEIEDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAYVAFRESSI 250
Query: 227 NLDYHWIYMVSQHITDLVSKILVLDPDSRYT-LPQIKNHAWFQGIDW 272
HW + ++ +L D + R L IK H++ + ID+
Sbjct: 251 PYPAHW----PTDLIQFINSMLKFDKEKRLVGLEAIKKHSYTERIDF 293
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 127 bits (320), Expect = 4e-29
Identities = 132/515 (25%), Positives = 213/515 (40%), Gaps = 37/515 (7%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ V A+ TG+ AIK+ K + + + K +N++ NHP I++
Sbjct: 69 LGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLY----REVNIMKKLNHPNIVR 124
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L LY V+++ R E + QL+ A+EY H +VHR
Sbjct: 125 LLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHR 184
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK-SNFCS 194
DLK ENLLL + KL I DFG ++ + + +F G+ Y +PEL K S
Sbjct: 185 DLKAENLLLDQQMKLKIADFGFSTTF---EPKAPLETFCGSPPYAAPELFRGKKYSGPEV 241
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
D W++G +LY G+ PF G N ++++ Y Y VS L+ K LVL+P
Sbjct: 242 DSWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYYVSIECESLIRKFLVLNPTQ 301
Query: 255 RYTLPQIKNHAWF-QGIDWTNKELIWKGIWQLFGNRNHNNFNGPSMMNKQLHVIDTTIKN 313
R +L + W G + N ++ + + N + S M + ++ ++KN
Sbjct: 302 RTSLSAVMADRWINMGYEQGNGLRPFQE--KPMDLHDVNRLSLLSNMGHKPRDVEQSLKN 359
Query: 314 IPIQPRKRKPMKVTQTTSSIVEWRKTLGLSPVSGS---VGPNGLPKQMKSHVPSRSTPNS 370
+K + T + + R T S SGS P +P + VP + PN
Sbjct: 360 -----QKFDDIYCTYMLLDVAKPRST-ACSEKSGSSFRETPTAMPGSSRIPVPI-AAPNV 412
Query: 371 PSRALTGKGYTKAMPNTAPPLETCKTPMMP-----VSPLYITTPGASASFSPKKFNNASD 425
+T K+ PN P T PM P ++PL +T P PKK+ S
Sbjct: 413 TISQVT-FALDKSTPNR--PAATSIRPMAPRLANALTPLPLTPP-------PKKYICCSA 462
Query: 426 SNRLLTPPASPKALKQGWVKILEIPYVSSSKKTFSSTEYSFIDDRLITRFITEQKSQIIN 485
S + P ++ Q + + K T S + ++ +T + +S I
Sbjct: 463 SKAANPRRSEPSSIPQSAMPKKGVGSPVDVKTTLLSAQRKLAVNQKLTSASHQIRSPITQ 522
Query: 486 S-SMLSLLTLEPNGQFSYTPKGDSTRQMISIVDQN 519
S S S T P F + +++ +V N
Sbjct: 523 SPSQASECTRTPPTHFEMLDSTSTPLKVLKLVASN 557
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 127 bits (319), Expect = 5e-29
Identities = 73/263 (27%), Positives = 138/263 (51%), Gaps = 13/263 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVT-IEKNTLNLLAHGNHPGII 74
LG G+++ V AV+ ++G+ +AIK+ +K+ I+ + K T + + +++L +HPG++
Sbjct: 173 LGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLHHPGVV 232
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVH 134
+ + F + + L+ V+++ +E K + QL++ L ++H V H
Sbjct: 233 QCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTH 292
Query: 135 RDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCS 194
RD+KPEN+L++++ L I+DFG+A + T T F GT Y++PE+L N
Sbjct: 293 RDIKPENILITNDFHLKISDFGLAKVIHGTGTFLET--FCGTMGYLAPEVLKSKNVNLDG 350
Query: 195 ------DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT----DLV 244
DIW++GC+LY + PF ++ E I Y ++ I+ DL+
Sbjct: 351 GYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLI 410
Query: 245 SKILVLDPDSRYTLPQIKNHAWF 267
+++L ++P+ R + + H WF
Sbjct: 411 NRMLEINPEKRISESEALQHPWF 433
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 127 bits (319), Expect = 5e-29
Identities = 78/263 (29%), Positives = 129/263 (48%), Gaps = 9/263 (3%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
+P+DF LG G + VY A +R + L A+KV K+ + + V E + +
Sbjct: 49 SPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLRE---IEIQ 105
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXX--XRFNEAWTKHFMCQLIDA 123
+ HP I++L FHD +Y L+ A RF+E + + Q+ +A
Sbjct: 106 SRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANA 165
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
L Y H V+HRDLKPEN+LL+S L + DFG +++ T N + + GT +Y+ PE
Sbjct: 166 LNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAH---TPN-NKRRTLCGTLDYLPPE 221
Query: 184 LLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDL 243
++ N + D W +G + Y+F G PPF + + + KI ++ + +S+ +L
Sbjct: 222 MVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKEL 281
Query: 244 VSKILVLDPDSRYTLPQIKNHAW 266
+ +L + R TL + H W
Sbjct: 282 IGGLLRKESKGRITLVDVMTHYW 304
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 127 bits (318), Expect = 7e-29
Identities = 77/259 (29%), Positives = 129/259 (49%), Gaps = 18/259 (6%)
Query: 28 VDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN------------HPGIIK 75
+D++ G+ V +H+ + KV I+K L+ LA G+ HP I++
Sbjct: 18 LDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIVR 77
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMCQLIDALEYIHGCKVVH 134
LY LY +L+ NE K + Q++ A+ Y H VVH
Sbjct: 78 LYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVH 137
Query: 135 RDLKPENLLL-SSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
RDLKPEN++ +G + +TDFG ++ L+++ G+ Y +PE+LL ++ +
Sbjct: 138 RDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSC---GSLAYSAPEILLGDEYDAP 194
Query: 194 S-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
+ DIW++G +L+ G PPF+ N+ I++ Y VS+ DL++++L DP
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254
Query: 253 DSRYTLPQIKNHAWFQGID 271
R +L +I+NH W QG+D
Sbjct: 255 KRRASLEEIENHPWLQGVD 273
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 127 bits (318), Expect = 7e-29
Identities = 75/262 (28%), Positives = 124/262 (46%), Gaps = 9/262 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF LG G + V+ + ++ T ++ A+KV K ++ + K + + H
Sbjct: 43 DFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQL---KREIEIQYHL 99
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXX--XRFNEAWTKHFMCQLIDALEY 126
HP I+ LY FHD + ++ +LD+A + NE F+ QL +AL Y
Sbjct: 100 RHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHY 159
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
H V+HRD+KPENLLL S+ L + DFG + + S + GT +Y++PE++
Sbjct: 160 CHSKGVIHRDIKPENLLLDSKLNLKLADFG----WSVVADHSKRHTLCGTMDYLAPEMVS 215
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
+F DIWA+G +L++ G PF + +I + +V+ L++
Sbjct: 216 NQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINA 275
Query: 247 ILVLDPDSRYTLPQIKNHAWFQ 268
I+ +P R L I H W +
Sbjct: 276 IIKKEPQERLPLVDIMAHPWIK 297
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 127 bits (318), Expect = 7e-29
Identities = 78/264 (29%), Positives = 133/264 (49%), Gaps = 7/264 (2%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
+G G+++ V A + TG+ A+K+ + II V + E + + L+ HP +++
Sbjct: 15 IGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLV---RHPCVVR 71
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
LY +Y +L++ R +E+ + + QLID ++Y H V HR
Sbjct: 72 LYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHR 131
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSN-FCS 194
DLKPENLLL S+G L I+DFG+++ ++ + GT YV+PE+L N +
Sbjct: 132 DLKPENLLLDSQGNLKISDFGLSA--LPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVA 189
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
DIW+ G +LY G PF + + KI ++ + L+++IL +P++
Sbjct: 190 DIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPET 249
Query: 255 RYTLPQIKNHAWFQGIDWTNKELI 278
R T+ +I+ WF D+T +LI
Sbjct: 250 RITIAEIRKDEWFLK-DYTPVQLI 272
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 127 bits (318), Expect = 7e-29
Identities = 81/275 (29%), Positives = 128/275 (46%), Gaps = 13/275 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ + LG G + YK D+S G+ +A K SK+ +I ++ V E L L
Sbjct: 85 YDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLT--G 142
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
P I++ + D +NL+ V++ ++E + Q+++ + H
Sbjct: 143 QPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVVHVCHF 202
Query: 130 CKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
VVHRDLKPEN LL S + + TDFG++ + VG+A YV+PE+L
Sbjct: 203 MGVVHRDLKPENFLLVSNEEDSPIKATDFGLS---VFIEEGKVYRDIVGSAYYVAPEVLH 259
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKI----VNLDYHWIYMVSQHITD 242
+N D+W+ G MLY G PPF GE E FE I ++L+ +S+ D
Sbjct: 260 RNYGKEI-DVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKD 318
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKEL 277
L+ K+L+ DP R T + H W ++K +
Sbjct: 319 LIRKMLIRDPKKRITAAEALEHPWMTDTKISDKPI 353
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 127 bits (318), Expect = 7e-29
Identities = 72/270 (26%), Positives = 137/270 (50%), Gaps = 13/270 (4%)
Query: 14 ERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGI 73
E+LG G + + D+ TG+ A K SK +++++ +K + +E + LA HP +
Sbjct: 48 EQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLA--GHPNV 105
Query: 74 IKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVV 133
+ L + + ++++ V++ R++E + L+ +++ H +V
Sbjct: 106 VNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEVRARVLFKHLMQVVKFCHDSGIV 165
Query: 134 HRDLKPENLL---LSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKS 190
HRDLKPEN+L +SS + + DFG+A+ + + LS T VG+ Y++PE +L
Sbjct: 166 HRDLKPENILMATMSSSSPIKLADFGLATYIKPGEKLSGT---VGSPFYIAPE-VLAGGY 221
Query: 191 NFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT----DLVSK 246
N +D+W+ G +LY G PPF G+ + F+ + D + +IT DL+
Sbjct: 222 NQAADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAKDLIRG 281
Query: 247 ILVLDPDSRYTLPQIKNHAWFQGIDWTNKE 276
+L +DP R + ++ H+W + + + +E
Sbjct: 282 MLCVDPSQRLSADEVLAHSWMEQLSESGQE 311
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 126 bits (317), Expect = 9e-29
Identities = 76/293 (25%), Positives = 144/293 (48%), Gaps = 22/293 (7%)
Query: 1 MSRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
+ RK DF + + +G+Y VY + + Q FA+K +K+++I N+++ +E++
Sbjct: 30 LRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERD 89
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQL 120
+L +P ++ +Y +F +L V+++ + + +
Sbjct: 90 ---ILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAET 146
Query: 121 IDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSS--------- 169
+ ALEY+H +VHRDLKP+NLL++S G + +TDFG++ ++ T NL
Sbjct: 147 VLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDARE 206
Query: 170 --TSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN 227
GT EY++PE++L+ D WA+G +LY+F G PF G+ F ++++
Sbjct: 207 FLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVIS 266
Query: 228 LDYHW---IYMVSQHITDLVSKILVLDPDSRYTLP---QIKNHAWFQGIDWTN 274
+ +W DL++ +L +P R ++K H +F+ +DW +
Sbjct: 267 DEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNS 319
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 126 bits (317), Expect = 9e-29
Identities = 81/276 (29%), Positives = 138/276 (49%), Gaps = 15/276 (5%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF F + +G G++ V +S+ Q++A+K SK ++ + E++ ++AH
Sbjct: 85 EDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERH---IMAH 141
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
N I++L++ F D++ LY V+DF P E W + +++ AL+ I
Sbjct: 142 ANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYD-IPEKWAIFYTMEVVLALDTI 200
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL-- 185
H VHRD+KP+N+LL S G L + DFG + A + S S+ VGT +Y+SPE+L
Sbjct: 201 HNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVS-SNAVGTPDYISPEVLQS 259
Query: 186 --LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV----NLDYHWIYMVSQH 239
+ N+ D W+VG LY+ G PF ++ + + KI+ +L + +S+
Sbjct: 260 QGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQ 319
Query: 240 ITDLVSKILV--LDPDSRYTLPQIKNHAWFQGIDWT 273
L+ L RY + IK H +F+ W+
Sbjct: 320 AKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWS 355
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 126 bits (316), Expect = 1e-28
Identities = 80/258 (31%), Positives = 126/258 (48%), Gaps = 8/258 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ + LG G+++ V R T AIK+ K + + N K + E + +L +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKML---D 75
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP IIKLY LY V ++A R NE+ + Q++ A++Y HG
Sbjct: 76 HPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHG 135
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QN 188
K+VHRDLK ENLLL + + I DFG + + + L +++ G+ Y +PE+ Q
Sbjct: 136 RKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELL---ATWCGSPPYAAPEVFEGQQ 192
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
DIW++G +LY G PF G ++++ + Y +S+ L+ ++L
Sbjct: 193 YEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRML 252
Query: 249 VLDPDSRYTLPQIKNHAW 266
VLDP R T+ QIK H W
Sbjct: 253 VLDPSKRLTIAQIKEHKW 270
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 125 bits (315), Expect = 2e-28
Identities = 82/267 (30%), Positives = 124/267 (45%), Gaps = 17/267 (6%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
F F E LG G++S V+ R TG+LFA+K K ++ ++ N + +L
Sbjct: 23 FIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLE------NEIAVLKKIK 76
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
H I+ L + + + Y V+ + E + Q++ A++Y+H
Sbjct: 77 HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHE 136
Query: 130 CKVVHRDLKPENLLL---SSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+VHRDLKPENLL K+MITDFG L+ + S+ GT YV+PE+L
Sbjct: 137 NGIVHRDLKPENLLYLTPEENSKIMITDFG----LSKMEQNGIMSTACGTPGYVAPEVLA 192
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYM----VSQHITD 242
Q + D W++G + Y G PPF E E FEKI Y + +S+ D
Sbjct: 193 QKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKD 252
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQG 269
+ +L DP+ RYT + +H W G
Sbjct: 253 FICHLLEKDPNERYTCEKALSHPWIDG 279
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 125 bits (315), Expect = 2e-28
Identities = 79/256 (30%), Positives = 130/256 (49%), Gaps = 9/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ VY A TG AIKV K+ I+ + + E + + LL HP I++
Sbjct: 18 LGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLL---RHPNIVE 74
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +YFV++ + K+F QL+ A+++ H V HR
Sbjct: 75 LHEVMATKSKIYFVMEHVKGGELFNKVSTGKLREDVARKYFQ-QLVRAVDFCHSRGVCHR 133
Query: 136 DLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFVGTAEYVSPELLLQN-KSNF 192
DLKPENLLL G L I+DFG++ S+ D L T+ GT YV+PE++ +N F
Sbjct: 134 DLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTT--CGTPAYVAPEVISRNGYDGF 191
Query: 193 CSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
+D+W+ G +L+ G PFR N + ++KI + + ++ L+ +IL +P
Sbjct: 192 KADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRLLKRILDPNP 251
Query: 253 DSRYTLPQIKNHAWFQ 268
++R + +I +WF+
Sbjct: 252 NTRVSTEKIMKSSWFR 267
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 125 bits (315), Expect = 2e-28
Identities = 83/278 (29%), Positives = 138/278 (48%), Gaps = 16/278 (5%)
Query: 9 DFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
DF LG G+Y V+ K G+L+A+KV +K ++ + K T + + L
Sbjct: 260 DFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVV-LE 318
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
A +P ++ L+Y F S LY VLDFA F E+ + ++ +++ ALE
Sbjct: 319 AIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALE 378
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+H +++RD+K EN+LL EG ++++DFG++ L A +N SF GT EY++PE++
Sbjct: 379 QLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTA-ENEYRAHSFCGTLEYMAPEII 437
Query: 186 LQNKSNFCS--DIWAVGCMLYQFTQGTPPFR---GENELAAFEKIVNLDYHWI-YMVSQH 239
S D W+VG + ++ G PF G+ + + + + + I S +
Sbjct: 438 RTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSAN 497
Query: 240 ITDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
D V K+L +P R +IK H +F GI+W
Sbjct: 498 ARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINW 535
Score = 70.1 bits (170), Expect = 1e-11
Identities = 70/281 (24%), Positives = 109/281 (37%), Gaps = 32/281 (11%)
Query: 7 PQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLA 66
P D R +G+Y T + VD ST +F K II +K + ++ L
Sbjct: 620 PDDLELGTRTSNGAYGTCHFVVDSSTDLVFLAK------IIPLSKFRPSEVDALISCALD 673
Query: 67 HGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
NH I+ + TF + + V+++ R +E + QL+ A+ +
Sbjct: 674 TTNHKNIVSYHGTFREKCETWIVMEYL----SGPELTASIRMDEDSCREIFLQLVMAVRH 729
Query: 127 IHGCKVVHRDLKPENLLLSS--EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
IH +H DLKPEN++ + + + + DFG A + + T +Y PE+
Sbjct: 730 IHSKHFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRY--TLDYAPPEM 787
Query: 185 LLQNKSNFCS---DIWAVGCMLYQFTQGTPPFRG-----ENELAAFEKI---------VN 227
L S DI+ +G LY G P+R ++ AA ++
Sbjct: 788 LADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQ 847
Query: 228 LDYHWIYMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
W S LVS L DP R TL I + W Q
Sbjct: 848 RSMRW-ESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQ 887
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 125 bits (314), Expect = 2e-28
Identities = 85/266 (31%), Positives = 134/266 (49%), Gaps = 16/266 (6%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ F E LG G+Y V KA + S+G+L AIK K I E + ++ E + +++ N
Sbjct: 53 YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRRE---IEIMSSLN 108
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II ++ F +S + V+++A + +E +HF Q++ A+ Y H
Sbjct: 109 HPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQ 168
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+VVHRDLK EN+LL + G + I DFG+ SNL T F G+ Y SPE++ N
Sbjct: 169 NRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKFLQT--FCGSPLYASPEIV--NG 223
Query: 190 SNFCS---DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
+ D W++G +LY GT PF G + ++I N Y S L+
Sbjct: 224 KPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSD-ACGLIRW 282
Query: 247 ILVLDPDSRYTLPQIKNHAWFQGIDW 272
+L+++P R TL + +H W ++W
Sbjct: 283 LLMVNPTRRATLEDVASHWW---VNW 305
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 125 bits (314), Expect = 2e-28
Identities = 84/279 (30%), Positives = 132/279 (47%), Gaps = 21/279 (7%)
Query: 1 MSRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHI---ISENKVKYVTI 57
M R D++ R+G GS++ V+ A RS+G A+K KK + + +N +K ++I
Sbjct: 1 MESARLVGDYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISI 60
Query: 58 EKNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFM 117
L+ +HP II+ Y + ++ VL++ + EA KHFM
Sbjct: 61 -------LSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFM 113
Query: 118 CQLIDALEYIHGCKVVHRDLKPENLLLSSE---GKLMITDFGVASNLAATDNLSSTSSFV 174
QL L+ + +HRDLKP+NLLLSS+ L I DFG A +L S +F
Sbjct: 114 RQLALGLQVLQEKHFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPE---SMAETFC 170
Query: 175 GTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV-----NLD 229
G+ Y++PE++ K + +D+W+ G +L+Q G PPF G N + F IV
Sbjct: 171 GSPLYMAPEIIRNQKYDAKADLWSAGAILFQLVTGKPPFDGNNHIQLFHNIVRDTELKFP 230
Query: 230 YHWIYMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
+ DL +L +P R T + NH + +
Sbjct: 231 EDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLR 269
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 125 bits (314), Expect = 2e-28
Identities = 88/324 (27%), Positives = 151/324 (46%), Gaps = 31/324 (9%)
Query: 5 RTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNL 64
R ++ KE LG G++S V + V +STG FA K+ + K + + + K + +
Sbjct: 9 RFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKL----EREARI 64
Query: 65 LAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDAL 124
+HP I++L+ + + Y V D ++EA H + Q+++++
Sbjct: 65 CRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESV 124
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
+ H VVHRDLKPENLLL+S+ K + + DFG+A + + + F GT Y+S
Sbjct: 125 NHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLA--IEVQGDHQAWFGFAGTPGYLS 182
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY----MVS 237
PE+L + DIWA G +LY G PPF E++ + +I Y + V+
Sbjct: 183 PEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVT 242
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAWF-------------QGIDWTNK-----ELIW 279
+L++++L ++P+ R T + H W + +D K +L
Sbjct: 243 PEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKG 302
Query: 280 KGIWQLFGNRNHNNFNGPSMMNKQ 303
+ + RN + F G SM+ K+
Sbjct: 303 AILTTMLATRNFSKFTGRSMITKK 326
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 125 bits (313), Expect = 3e-28
Identities = 79/252 (31%), Positives = 120/252 (47%), Gaps = 31/252 (12%)
Query: 5 RTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKV---KYVTIEKNT 61
R DF LG G+Y V D +T +L+A+K K I+ K +KN
Sbjct: 123 RNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKND 182
Query: 62 LN--------------------LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXX 101
N +L+ HP I+KL+Y+FHD+ LY +L + P
Sbjct: 183 GNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYH 242
Query: 102 XXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGV---A 158
+E + ++ AL ++H VV+RDLKPEN LL+ G L++TDFG+ +
Sbjct: 243 LKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKS 302
Query: 159 SNLAATD-----NLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPF 213
+N +A D N+++ S +GT EY +PE+LL + D +++GC+LY G PP+
Sbjct: 303 ANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPY 362
Query: 214 RGENELAAFEKI 225
G N KI
Sbjct: 363 TGSNHKVIINKI 374
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 125 bits (313), Expect = 3e-28
Identities = 75/272 (27%), Positives = 137/272 (49%), Gaps = 8/272 (2%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T DF+F LG G++ V A + + +AIKV K+ I+ +++ + EK+ +
Sbjct: 568 TLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVA 627
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
HP ++ L+ +F S +YFV+++ +F+ + + ++ AL+
Sbjct: 628 NKEKHPFLLNLFASFQTSTRVYFVMEYI-LGGDLMVHIQRQQFSVKRARFYGAEVCLALK 686
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
Y H + +RDLK +N+LL +G + I D+G+ N +TS+F GT E+++PE+L
Sbjct: 687 YFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGN--TTSTFCGTPEFMAPEIL 744
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVS 245
L+ + + D WA G ++YQ G PF+GE+E F+ I++ + + + L+
Sbjct: 745 LEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPADAVSLLR 804
Query: 246 KILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
+L DP+ R ++ H +F I W
Sbjct: 805 GLLTRDPNQRLGSGPKDANEVMAHPFFASIVW 836
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 125 bits (313), Expect = 3e-28
Identities = 75/270 (27%), Positives = 128/270 (46%), Gaps = 13/270 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENK-VKYVTIEKNTLNLLAHG 68
+ E LG G ++ V K + TG+ +A K K+ + S + V IE+ +N+L
Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIERE-VNILREI 71
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP II L+ F + ++ +L+ E F+ Q++D + Y+H
Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query: 129 GCKVVHRDLKPENLLLSSEG----KLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
++ H DLKPEN++L + ++ + DFG+A + A + + GT E+V+PE+
Sbjct: 132 SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEF---KNIFGTPEFVAPEI 188
Query: 185 LLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKI--VNLDYHWIYM--VSQHI 240
+ +D+W++G + Y G PF GE + I VN D+ Y S+
Sbjct: 189 VNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELA 248
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAWFQGI 270
D + ++LV DP R T+ Q H+W + I
Sbjct: 249 KDFIRRLLVKDPKRRMTIAQSLEHSWIKAI 278
>Hs4507271 [T] KOG0583 Serine/threonine protein kinase
Length = 433
Score = 125 bits (313), Expect = 3e-28
Identities = 86/259 (33%), Positives = 125/259 (48%), Gaps = 9/259 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIIS-ENKVKYVTIEKNTLNLLAHGNHPGII 74
LG GSY V + +D T A+K+ KK + N V E L L H N ++
Sbjct: 55 LGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLV 114
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXX-XXRFNEAWTKHFMCQLIDALEYIHGCKVV 133
+ Y + + +Y V+++ RF + CQLID LEY+H +V
Sbjct: 115 DVLYN-EEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIV 173
Query: 134 HRDLKPENLLLSSEGKLMITDFGVASNL--AATDNLSSTSSFVGTAEYVSPELL--LQNK 189
H+D+KP NLLL++ G L I+D GVA L A D+ TS G+ + PE+ L
Sbjct: 174 HKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQ--GSPAFQPPEIANGLDTF 231
Query: 190 SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILV 249
S F DIW+ G LY T G PF G+N FE I Y ++DL+ +L
Sbjct: 232 SGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLE 291
Query: 250 LDPDSRYTLPQIKNHAWFQ 268
+P R+++ QI+ H+WF+
Sbjct: 292 YEPAKRFSIRQIRQHSWFR 310
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 125 bits (313), Expect = 3e-28
Identities = 82/282 (29%), Positives = 139/282 (49%), Gaps = 26/282 (9%)
Query: 16 LGHGSYSTVYKAVDR-STGQLFAIKVCSKKHIIS-----ENKVKYVT------IEKNTLN 63
LG G++S V A + S G+ FA+K+ KK + EN+++ + + LN
Sbjct: 37 LGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLN 96
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
HP I++L T+ D +Y V++ + E H + Q+++A
Sbjct: 97 G-TRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEA 155
Query: 124 LEYIHGCKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
++Y+H VVHRDLKPENLL S + K+MI+DFG L+ ++ ++ GT YV
Sbjct: 156 VDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFG----LSKMEDSGIMATACGTPGYV 211
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY-----HWIYM 235
+PE+L Q D+W++G + Y G PPF EN+ F +I+ D+ +W
Sbjct: 212 APEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYW-DE 270
Query: 236 VSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKEL 277
+S+ + ++ + + RYT Q HAW G + +++ +
Sbjct: 271 ISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNI 312
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 124 bits (312), Expect = 3e-28
Identities = 78/280 (27%), Positives = 139/280 (48%), Gaps = 18/280 (6%)
Query: 8 QDFSFKERLGHGSYSTVY---KAVDRSTGQLFAIKVCSKKHIISENKV-KYVTIEKNTLN 63
++F + LG G+Y V+ K TG+L+A+KV K I+ + K ++ E+ L
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+ P ++ L+Y F L+ +LD+ RF E + ++ +++ A
Sbjct: 107 HIRQS--PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 164
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPE 183
LE++H +++RD+K EN+LL S G +++TDFG++ A D SF GT EY++P+
Sbjct: 165 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVA-DETERAYSFCGTIEYMAPD 223
Query: 184 LLLQNKSNF--CSDIWAVGCMLYQFTQGTPPFRGENE----LAAFEKIVNLDYHWIYMVS 237
++ S D W++G ++Y+ G PF + E +I+ + + +S
Sbjct: 224 IVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS 283
Query: 238 QHITDLVSKILVLDPDSRY-----TLPQIKNHAWFQGIDW 272
DL+ ++L+ DP R +IK H +FQ I+W
Sbjct: 284 ALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINW 323
Score = 123 bits (308), Expect = 1e-27
Identities = 108/381 (28%), Positives = 168/381 (43%), Gaps = 31/381 (8%)
Query: 9 DFSFKER-LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
D K++ LG GS+S K V + + Q +K+ SK+ + N K +T K L
Sbjct: 424 DLDLKDKPLGEGSFSICRKCVHKKSNQALQVKIISKR--MEANTQKEITALK-----LCE 476
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
G HP I+KL+ FHD + + V++ F+E + M +L+ AL ++
Sbjct: 477 G-HPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHM 535
Query: 128 HGCKVVHRDLKPENLLLSSEG---KLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPEL 184
H VVHRDLKPENLL + E ++ I DFG A + T F T PEL
Sbjct: 536 HDLGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCF--TLHSCRPEL 593
Query: 185 LLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE-------LAAFEKIVNLDYHW----I 233
L QN + D+W++G +LY G PF+ + + +KI D+ +
Sbjct: 594 LNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAW 653
Query: 234 YMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ-GIDWTNKELIWKGIWQLFGNRNHN 292
VSQ DL+ +L +DP+ R + ++ + W Q G ++ L+ I G H
Sbjct: 654 KNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHT 713
Query: 293 NFNGPSMMNKQLHVIDTTIKNIPIQP-RKRKPMKVTQTTSSIVEWRKTLGLSPVSGSVGP 351
+ ++N+ P KR+ MK T T++ E R+ S S S
Sbjct: 714 CVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTST---ETRRGSSESSHSSSSHS 770
Query: 352 NGLPKQMKSHVPSR-STPNSP 371
+G K+ PS + N+P
Sbjct: 771 HGKTTPTKTLQPSNPADSNNP 791
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 124 bits (312), Expect = 3e-28
Identities = 78/268 (29%), Positives = 132/268 (49%), Gaps = 8/268 (2%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
KR + +G G+++ V A + TG+ A+K+ K+ ++ + + E T+
Sbjct: 8 KRRVGKYEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMK 67
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
L+ HP +++LY ++ +L++ R E + + QLI A
Sbjct: 68 LI---KHPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHA 124
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFVGTAEYVS 181
++Y H V HRDLKPENLLL S G L I+DFG++ S D L TS GT YV+
Sbjct: 125 VDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTS--CGTPNYVA 182
Query: 182 PELLL-QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHI 240
PE+L + +D+W+ G +LY G PF N + ++KI + +++ +S
Sbjct: 183 PEVLNDRGYDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCPPWLSLGA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
L+++IL +P +R T ++ WF+
Sbjct: 243 MKLITRILDPNPMTRVTPQEVFEDEWFK 270
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 124 bits (311), Expect = 4e-28
Identities = 82/259 (31%), Positives = 126/259 (47%), Gaps = 8/259 (3%)
Query: 16 LGHGSYSTVYKAVD-RSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGII 74
LG G+++ VY+A D ++ G+ AIKV KK + K K ++++ HP I+
Sbjct: 34 LGSGAFAKVYQAEDLQNGGESVAIKVVQKKRL----KDGLTAHVKREISVMRRLRHPHIV 89
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVH 134
L +YFV++ A RF E+ ++ + QLI A+ Y H V H
Sbjct: 90 LLSEVLATKTKIYFVMELAKGGELFSRVTSN-RFTESLSRKYFRQLISAVRYCHARGVFH 148
Query: 135 RDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QNKSNFC 193
RDLKPENLLL L ++DFG+++ + GT YV+PELLL +
Sbjct: 149 RDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSK 208
Query: 194 SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPD 253
+DIW+ G +L+ G PFR N + + KI Y S + L+ ++L +P+
Sbjct: 209 ADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLPDWTSSDLRKLLRRLLEPNPE 268
Query: 254 SRYTLPQIKNHAWF-QGID 271
R T+ +I WF G+D
Sbjct: 269 LRITVEEILKDPWFNHGVD 287
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 124 bits (311), Expect = 4e-28
Identities = 72/256 (28%), Positives = 130/256 (50%), Gaps = 5/256 (1%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIK-VCSKKHIISENKVK-YVTIEKNTLNLLAHGNHPGI 73
+G G++ TVY ++ +G+L A+K V + S+ K + ++ + + LL + +HP I
Sbjct: 74 IGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNI 133
Query: 74 IKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVV 133
++ T + E L +L+F P F E+ + + QL+ LEY+H ++
Sbjct: 134 VRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIM 193
Query: 134 HRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
HRD+K N+L+ ++G + + DFG + +A +S S GT +++PE++LQ +F
Sbjct: 194 HRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFS 253
Query: 194 SDIWAVGCMLYQFTQGTPPFRGE-NELAAFEKIVNLDYHWIY--MVSQHITDLVSKILVL 250
+DIW+VGC + + G P+ + E+AA I H +S D + K L
Sbjct: 254 ADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQ 313
Query: 251 DPDSRYTLPQIKNHAW 266
+P+ R T ++ W
Sbjct: 314 EPNLRPTASELLKVKW 329
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 124 bits (310), Expect = 6e-28
Identities = 82/332 (24%), Positives = 149/332 (44%), Gaps = 71/332 (21%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF + +G G++ V + TG+++A+K K + ++++ +V E++ +LA
Sbjct: 350 EDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERD---VLAG 406
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+ P ++ LYY+F D++ LY +++F P F E T+ +M + I A+E I
Sbjct: 407 SDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETI 466
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAAT----------------------- 164
H +HRD+KP+N+L+ G + ++DFG+++ T
Sbjct: 467 HKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPG 526
Query: 165 ------------------DNLSSTSS------------------FVGTAEYVSPELLLQN 188
D++S T S VGT +Y++PE+ L
Sbjct: 527 TYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQ 586
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHIT----DLV 244
D W++G ++Y+ G PPF E + KI+N + + HI+ DL+
Sbjct: 587 GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLI 646
Query: 245 SKILVLDPDSRY----TLPQIKNHAWFQGIDW 272
++L D R +IK+H +F+G+DW
Sbjct: 647 RRLLT-HADQRLGRHGGADEIKSHPFFRGVDW 677
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 124 bits (310), Expect = 6e-28
Identities = 84/311 (27%), Positives = 145/311 (46%), Gaps = 56/311 (18%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G++ V A T L+A K KK ++ N+V +V E++ +LA ++ +++
Sbjct: 711 LGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERD---ILAEADNEWVVR 767
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
LYY+F D +NLYFV+D+ P F E+ + ++ +L A+E +H +HR
Sbjct: 768 LYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHR 827
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAAT--------------DNLSSTS---------- 171
D+KP+N+L+ +G + +TDFG+ + T D++ ++
Sbjct: 828 DIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRC 887
Query: 172 ---------------------SFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGT 210
S VGT Y++PE+LL+ D W+VG +L++ G
Sbjct: 888 GDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQ 947
Query: 211 PPFRGENELAAFEKIVN----LDYHWIYMVSQHITDLVSKILVLDPDSRY---TLPQIKN 263
PPF + L K++N L +S +DL+ K L P+ R +IK
Sbjct: 948 PPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIK-LCRGPEDRLGKNGADEIKA 1006
Query: 264 HAWFQGIDWTN 274
H +F+ ID+++
Sbjct: 1007 HPFFKTIDFSS 1017
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 124 bits (310), Expect = 6e-28
Identities = 78/261 (29%), Positives = 128/261 (48%), Gaps = 8/261 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ ++ LG G V V TGQ AIK+ +++ + SE+ + V E L L+
Sbjct: 51 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL-SESVLMKVEREIAILKLI---E 106
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP ++KL+ + + + LY VL+ R + F Q++ AL++ H
Sbjct: 107 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 166
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+ HRDLKPENLLL + + I DFG+AS L D+L TS G+ Y PE++ K
Sbjct: 167 YSICHRDLKPENLLLDEKNNIRIADFGMAS-LQVGDSLLETS--CGSPHYACPEVIKGEK 223
Query: 190 -SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+D+W+ G +L+ G PF +N EK+ +H + + L+ ++
Sbjct: 224 YDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMI 283
Query: 249 VLDPDSRYTLPQIKNHAWFQG 269
++P+ R +L QI+ H W+ G
Sbjct: 284 EVEPEKRLSLEQIQKHPWYLG 304
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 124 bits (310), Expect = 6e-28
Identities = 79/282 (28%), Positives = 144/282 (51%), Gaps = 25/282 (8%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + +G G++ V R G+++A+K+ +K ++ + E++ +L +G
Sbjct: 82 DFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERD---VLVYG 138
Query: 69 NHPGIIKLYYTFHDSENLYFVLDF-APXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+ I L+Y F D +NLYFV+D+ E+ K ++ +++ A++ +
Sbjct: 139 DRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSL 198
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL- 186
H VHRD+KP+N+LL +G + + DFG + A +++S + VGT +Y+SPE+L
Sbjct: 199 HRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVASNVA-VGTPDYISPEILRA 257
Query: 187 ----QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN----LDY-----HWI 233
+ + D W++G +Y+ GT PF E + + KI++ LD+ W+
Sbjct: 258 MEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEIDWV 317
Query: 234 YMVSQHITDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDW 272
VS+ DL+ + L+ D R+ L + H +F+GIDW
Sbjct: 318 --VSEEAKDLIRQ-LICSSDVRFGRNGLSDFQLHPFFEGIDW 356
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 124 bits (310), Expect = 6e-28
Identities = 78/281 (27%), Positives = 135/281 (47%), Gaps = 21/281 (7%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF +G GSY+ V +A ST Q++AIK+ K+ + + +V EK+ A
Sbjct: 252 DFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFE--AAS 309
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
N+P ++ L+ F L+FV++F P + E + + ++I AL ++H
Sbjct: 310 NYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLH 369
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+++RDLK +N+L+ +EG + +TD+G+ +L TS+F GT Y++PE+L +
Sbjct: 370 SRGIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDL--TSTFCGTPNYIAPEILRGD 427
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPF--------RGENELAAFEKIVNLDYHWIYMVSQHI 240
+ F D WA+G ++++ G PF E F+ I+ +S
Sbjct: 428 EYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRA 487
Query: 241 TDLVSKILVLDPDSRY--------TLPQIKNHAWFQG-IDW 272
+ ++ L DP R L +K H +F+G IDW
Sbjct: 488 SGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDW 528
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 124 bits (310), Expect = 6e-28
Identities = 76/264 (28%), Positives = 128/264 (47%), Gaps = 13/264 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+S +LG G + T + VD+ TG+ FA K +K+ + + V+ V E ++ L+
Sbjct: 134 YSVGRKLGQGQFGTTFLCVDKKTGKEFACKTIAKRKLTTPEDVEDVRREIQIMHHLS--G 191
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP +I++ + D+ ++ V++ + E ++ +E H
Sbjct: 192 HPNVIQIVGAYEDAVAVHVVMEICAGGELFDRIIQRGHYTEKKAAELARIIVGVIEACHS 251
Query: 130 CKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
V+HRDLKPEN L S E L DFG++ + + VG+ YV+PE+L
Sbjct: 252 LGVMHRDLKPENFLFVSGDEEAALKTIDFGLSVFFKPGETFTDV---VGSPYYVAPEVLR 308
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY----MVSQHITD 242
++ S+ C D+W+ G ++Y G PPF E E FE+++ D +I VS+ D
Sbjct: 309 KHYSHEC-DVWSAGVIIYILLSGVPPFWDETEQGIFEQVLKGDLDFISEPWPSVSESAKD 367
Query: 243 LVSKILVLDPDSRYTLPQIKNHAW 266
LV ++L+ DP R T ++ H W
Sbjct: 368 LVRRMLIRDPKKRMTTHEVLCHPW 391
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 124 bits (310), Expect = 6e-28
Identities = 77/270 (28%), Positives = 130/270 (47%), Gaps = 21/270 (7%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
+ + D+ F +G G + +V R G FA K K +V+
Sbjct: 100 KNKIDDDYVFGRNIGKGKFGSVRICKSRKNGTEFACKTLKKGEETVHREVE--------- 150
Query: 63 NLLAH-GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
++ H HP ++ L+ + +S+ + V++ R++E + L+
Sbjct: 151 -IMQHLSGHPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLM 209
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
+ Y H VVHRD+KPEN+LL++ GK+ + DFG+A +A L S G+ YV+
Sbjct: 210 LVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLAMRIAKGQTL---SGLAGSPAYVA 266
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKI--VNLDYH---WIYMV 236
PE+L +N S D+W+ G +LY G PF+G++ A FE I V LD++ W V
Sbjct: 267 PEVLSENYSEKV-DVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVW-ESV 324
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAW 266
S+ DL++++L + +R T ++ H W
Sbjct: 325 SKPARDLLARMLTREESARITADEVLRHPW 354
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 123 bits (309), Expect = 8e-28
Identities = 77/275 (28%), Positives = 132/275 (48%), Gaps = 13/275 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+S + LG G + Y + TG +A K K+ +IS+ + V E + L+
Sbjct: 80 YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQDKEDVKREIQIMQYLS--G 137
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
P I+++ + D ++++ V++ ++E + +++ ++ H
Sbjct: 138 QPNIVEIKGAYEDRQSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIRSIVNVVQICHF 197
Query: 130 CKVVHRDLKPENLLLSSE---GKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
VVHRDLKPEN LLSS+ L TDFG++ + VG+A YV+PE+L
Sbjct: 198 MGVVHRDLKPENFLLSSKEENAMLKATDFGLS---VFIEEGKVYRDIVGSAYYVAPEVLR 254
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY----MVSQHITD 242
++ DIW+ G +LY G PPF ENE F++++ + ++ +S+ D
Sbjct: 255 RSYGKEI-DIWSAGVILYILLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSISESAKD 313
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKEL 277
LV K+L DP R T Q+ H W +G + +K +
Sbjct: 314 LVRKMLTKDPKRRITAAQVLEHPWIKGGEAPDKPI 348
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 123 bits (308), Expect = 1e-27
Identities = 76/259 (29%), Positives = 127/259 (48%), Gaps = 8/259 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ + +G G+++ V A TG+ A+K+ K + S + K E + +L
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR-EVRIMKVL--- 74
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP I+KL+ + LY V+++A R E + Q++ A++Y H
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+VHRDLK ENLLL ++ + I DFG ++ + L +F G+ Y +PEL
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKL---DTFCGSPPYAAPELFQGK 191
Query: 189 KSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
K + D+W++G +LY G+ PF G+N E+++ Y + +S +L+ K
Sbjct: 192 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 251
Query: 248 LVLDPDSRYTLPQIKNHAW 266
L+L+P R TL QI W
Sbjct: 252 LILNPSKRGTLEQIMKDRW 270
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 123 bits (308), Expect = 1e-27
Identities = 76/259 (29%), Positives = 127/259 (48%), Gaps = 8/259 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ + +G G+++ V A TG+ A+K+ K + S + K E + +L
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR-EVRIMKVL--- 74
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP I+KL+ + LY V+++A R E + Q++ A++Y H
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+VHRDLK ENLLL ++ + I DFG ++ + L +F G+ Y +PEL
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKL---DTFCGSPPYAAPELFQGK 191
Query: 189 KSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
K + D+W++G +LY G+ PF G+N E+++ Y + +S +L+ K
Sbjct: 192 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 251
Query: 248 LVLDPDSRYTLPQIKNHAW 266
L+L+P R TL QI W
Sbjct: 252 LILNPSKRGTLEQIMKDRW 270
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 123 bits (308), Expect = 1e-27
Identities = 76/259 (29%), Positives = 127/259 (48%), Gaps = 8/259 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ + +G G+++ V A TG+ A+K+ K + S + K E + +L
Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR-EVRIMKVL--- 107
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP I+KL+ + LY V+++A R E + Q++ A++Y H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+VHRDLK ENLLL ++ + I DFG ++ + L +F G+ Y +PEL
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKL---DTFCGSPPYAAPELFQGK 224
Query: 189 KSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
K + D+W++G +LY G+ PF G+N E+++ Y + +S +L+ K
Sbjct: 225 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 284
Query: 248 LVLDPDSRYTLPQIKNHAW 266
L+L+P R TL QI W
Sbjct: 285 LILNPSKRGTLEQIMKDRW 303
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 122 bits (307), Expect = 1e-27
Identities = 75/253 (29%), Positives = 125/253 (48%), Gaps = 3/253 (1%)
Query: 3 RKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTL 62
RK + +F + LG G++ V + ++T +L AIKV K +II + ++ EK
Sbjct: 817 RKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVF 876
Query: 63 NLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLID 122
L HP + LY +F +YF ++F R + K + +++
Sbjct: 877 LLATKTKHPFLTNLYCSFQTENRIYFAMEFI-GGGDLMWHVQNQRLSVRRAKFYAAEVLL 935
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
AL+Y H V++RDLK EN+LL+ EG + I D+G+ + N TS+F GT E+++P
Sbjct: 936 ALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGN--RTSTFCGTPEFMAP 993
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITD 242
E+L + + D WA G +LYQ PF G++E F I+ + + ++ I
Sbjct: 994 EILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQ 1053
Query: 243 LVSKILVLDPDSR 255
+ +L DP+ R
Sbjct: 1054 IFQGLLTKDPEKR 1066
>Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 588
Score = 122 bits (307), Expect = 1e-27
Identities = 80/284 (28%), Positives = 137/284 (48%), Gaps = 30/284 (10%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT-------- 61
++ K+ +G GSY V A + + +A+KV SKK +I + + T
Sbjct: 165 YTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCI 224
Query: 62 ------------LNLLAHGNHPGIIKLYYTFHD--SENLYFVLDFAPXXXXXXXXXXXXR 107
+ +L +HP ++KL D ++LY V +
Sbjct: 225 QPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELV-NQGPVMEVPTLKP 283
Query: 108 FNEAWTKHFMCQLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNL 167
+E + + LI +EY+H K++HRD+KP NLL+ +G + I DFGV++ +D L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 168 SSTSSFVGTAEYVSPELLLQNKSNFCS---DIWAVGCMLYQFTQGTPPFRGENELAAFEK 224
S + VGT +++PE L + + F D+WA+G LY F G PF E + K
Sbjct: 344 LSNT--VGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSK 401
Query: 225 IVN--LDYHWIYMVSQHITDLVSKILVLDPDSRYTLPQIKNHAW 266
I + L++ +++ + DL++++L +P+SR +P+IK H W
Sbjct: 402 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPW 445
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 122 bits (307), Expect = 1e-27
Identities = 123/488 (25%), Positives = 199/488 (40%), Gaps = 67/488 (13%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAWFQGIDWTNKELIWKGIWQLFGNRNHNNFNGPSMM 300
L+ +L ++P R T Q W N+E + I +
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPWI-----CNRERVASAIHR---------------- 281
Query: 301 NKQLHVIDTTIKNIPIQPRKRKPMKVTQTTSSIVEWRKTLGLSPVSGSVGPNGLPKQMKS 360
T+ + +RK + L S +GSV NG S
Sbjct: 282 -------QDTVDCLKKFNARRKLKAAISAVKMVTRMSGVLRTSDSTGSVASNGSTTHDAS 334
Query: 361 HVPSRST-PNSPS---RALTGKGYTKAMPNTAPPLETCKTPMMPVSPLYITTPGASASFS 416
V S+ P SP+ LT T+ + N L K
Sbjct: 335 QVAGTSSQPTSPAAEGAILTTMIATRNLSNLGRNLLNKK-----------------EQGP 377
Query: 417 PKKFNNASDSNRLLTPPASPKALKQGWVKILEIPYVSSSKKTFSSTEYSFIDDRLITRFI 476
P +S+S++ + S KA KQ V++ + + S K F + Y+ + D +T F
Sbjct: 378 PSTIKESSESSQTIDDNDSEKAQKQDIVRVTQTLLDAISCKDFET--YTRLCDTSMTCFE 435
Query: 477 TEQKSQII 484
E +I
Sbjct: 436 PEALGNLI 443
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 122 bits (307), Expect = 1e-27
Identities = 73/254 (28%), Positives = 125/254 (48%), Gaps = 5/254 (1%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ VY A + TG+ AIKV K+ + + + E + + L+ HP ++
Sbjct: 18 LGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLV---RHPHVVF 74
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +YF +++ + E + + QLI A++Y H V HR
Sbjct: 75 LHEVMASKTKIYFAMEYVKGGELFDKVSKG-KLKENIARKYFQQLIGAIDYCHSRGVYHR 133
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL-LQNKSNFCS 194
DLKPENLLL G L I+DFG+++ + + GT YV+PE++ + +
Sbjct: 134 DLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKA 193
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
D+W+ G +LY G PF +N + + KI ++ + L+S+IL +P+S
Sbjct: 194 DVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLSRILDPNPNS 253
Query: 255 RYTLPQIKNHAWFQ 268
R + +I ++WFQ
Sbjct: 254 RIKIEKIMENSWFQ 267
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 122 bits (306), Expect = 2e-27
Identities = 74/259 (28%), Positives = 128/259 (48%), Gaps = 8/259 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ + +G G+++ V A TG+ AIK+ K + + ++ + E + +L
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKIL--- 110
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP I+KL+ + LY ++++A R E + Q++ A++Y H
Sbjct: 111 NHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
++VHRDLK ENLLL ++ + I DFG ++ L +F G+ Y +PEL
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKL---DTFCGSPPYAAPELFQGK 227
Query: 189 KSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
K + D+W++G +LY G+ PF G+N E+++ Y + +S +L+ +
Sbjct: 228 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287
Query: 248 LVLDPDSRYTLPQIKNHAW 266
LVL+P R TL QI W
Sbjct: 288 LVLNPIKRGTLEQIMKDRW 306
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 122 bits (306), Expect = 2e-27
Identities = 74/259 (28%), Positives = 129/259 (49%), Gaps = 8/259 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ ++ +G G+++ V A TG+ A+K+ K + + ++ + E + +L
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKIL--- 114
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
NHP I+KL+ + LY V+++A R E + Q++ A++Y H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+VHRDLK ENLLL + + I DFG ++ + L +F G+ Y +PEL
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKL---DTFCGSPPYAAPELFQGK 231
Query: 189 KSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
K + D+W++G +LY G+ PF G+N E+++ Y + +S +L+ K+
Sbjct: 232 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKL 291
Query: 248 LVLDPDSRYTLPQIKNHAW 266
LVL+P R +L QI W
Sbjct: 292 LVLNPIKRGSLEQIMKDRW 310
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 122 bits (306), Expect = 2e-27
Identities = 75/269 (27%), Positives = 127/269 (46%), Gaps = 13/269 (4%)
Query: 4 KRTPQD-----FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIE 58
+R QD + + +G G+++ V A TG AIK+ K + + K
Sbjct: 111 RRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLF--- 167
Query: 59 KNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMC 118
+ ++ +HP I+KLY + LY VL++A R E +
Sbjct: 168 -REVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFR 226
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
Q++ A++Y+H ++HRDLK ENLLL + + I DFG ++ + + L +F G+
Sbjct: 227 QIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKL---DTFCGSPP 283
Query: 179 YVSPELLLQNKSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVS 237
Y +PEL K + D+W++G +LY G+ PF G+N E+++ Y + +S
Sbjct: 284 YAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 343
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAW 266
+L+ K LV++P R +L I W
Sbjct: 344 TDCENLLKKFLVINPQRRSSLDNIMKDRW 372
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 122 bits (306), Expect = 2e-27
Identities = 75/269 (27%), Positives = 127/269 (46%), Gaps = 13/269 (4%)
Query: 4 KRTPQD-----FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIE 58
+R QD + + +G G+++ V A TG AIK+ K + + K
Sbjct: 159 RRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLF--- 215
Query: 59 KNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMC 118
+ ++ +HP I+KLY + LY VL++A R E +
Sbjct: 216 -REVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFR 274
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
Q++ A++Y+H ++HRDLK ENLLL + + I DFG ++ + + L +F G+
Sbjct: 275 QIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKL---DTFCGSPP 331
Query: 179 YVSPELLLQNKSNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVS 237
Y +PEL K + D+W++G +LY G+ PF G+N E+++ Y + +S
Sbjct: 332 YAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 391
Query: 238 QHITDLVSKILVLDPDSRYTLPQIKNHAW 266
+L+ K LV++P R +L I W
Sbjct: 392 TDCENLLKKFLVINPQRRSSLDNIMKDRW 420
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 122 bits (306), Expect = 2e-27
Identities = 83/300 (27%), Positives = 139/300 (45%), Gaps = 19/300 (6%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
+G G+++ V A + TG AIK+ +K I+ V + K ++++ HP I++
Sbjct: 17 IGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQI---KREISIMKIVRHPNIVR 73
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
LY +Y VL+F R E+ ++ + QL+DA+ + H V HR
Sbjct: 74 LYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHR 133
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QNKSNFCS 194
DLKPENLLL + G L ++DFG+++ + + + GT YV+PE+L Q +
Sbjct: 134 DLKPENLLLDTNGNLKVSDFGLSA--LPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAA 191
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
DIW+ G +L+ G PF + + KI ++ S + L+ +IL +P +
Sbjct: 192 DIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKT 251
Query: 255 RYTLPQIKNHAWF------------QGIDWTNKELIWKGIWQLFGNRN-HNNFNGPSMMN 301
R + IK WF + ++ + ++ GI + N N GP MMN
Sbjct: 252 RIQIQGIKKDPWFRLNYVPIRAREEEEVNLDDIRAVFDGIEGSYVAENVERNDEGPLMMN 311
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 122 bits (305), Expect = 2e-27
Identities = 72/253 (28%), Positives = 127/253 (49%), Gaps = 6/253 (2%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G ++ Y+ +R+T ++ A KV K ++ + + +T E L H N I+K
Sbjct: 44 LGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELGHIN---IVK 100
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ F D+ N+Y L+ E ++F Q++D + Y+H ++HR
Sbjct: 101 LFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIHR 160
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
D+K NL L+ + + I DFG+A+ + + + GT Y++PE+L + +F D
Sbjct: 161 DMKLGNLFLNDDLVVKIGDFGLATTVNGDER---KKTLCGTPNYIAPEVLNKAGHSFEVD 217
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSR 255
IWAVGC+LY G PPF ++ + +I + +Y + +Q L+ K+L +P R
Sbjct: 218 IWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRR 277
Query: 256 YTLPQIKNHAWFQ 268
T Q++ +F+
Sbjct: 278 PTAKQVQRDGFFK 290
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 122 bits (305), Expect = 2e-27
Identities = 74/269 (27%), Positives = 131/269 (48%), Gaps = 8/269 (2%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+F LG G + V + RS Q +AIK K II+ ++V+ + EK +
Sbjct: 262 NFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAM 321
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP ++ LY F +++ FV+++A F E + ++ L+Y+H
Sbjct: 322 RHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDV-FLEPRAVFYAACVVLGLQYLH 380
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
K+++RDLK +NLLL +EG + I DFG+ + T +F GT E+++PE+L +
Sbjct: 381 ENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGD--RTGTFCGTPEFLAPEVLTET 438
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D W +G ++++ G PF G++E F+ IVN + + +S ++ ++L
Sbjct: 439 SYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLL 498
Query: 249 VLDPDSRY-----TLPQIKNHAWFQGIDW 272
+P+ R +K A+F+ I W
Sbjct: 499 RKNPERRLGSSERDAEDVKKQAFFRSIVW 527
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 122 bits (305), Expect = 2e-27
Identities = 74/269 (27%), Positives = 131/269 (48%), Gaps = 8/269 (2%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+F LG G + V + RS Q +AIK K II+ ++V+ + EK +
Sbjct: 956 NFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAM 1015
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP ++ LY F +++ FV+++A F E + ++ L+Y+H
Sbjct: 1016 RHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDV-FLEPRAVFYAACVVLGLQYLH 1074
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
K+++RDLK +NLLL +EG + I DFG+ + T +F GT E+++PE+L +
Sbjct: 1075 ENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGD--RTGTFCGTPEFLAPEVLTET 1132
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
D W +G ++++ G PF G++E F+ IVN + + +S ++ ++L
Sbjct: 1133 SYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLL 1192
Query: 249 VLDPDSRY-----TLPQIKNHAWFQGIDW 272
+P+ R +K A+F+ I W
Sbjct: 1193 RKNPERRLGSSERDAEDVKKQAFFRSIVW 1221
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 122 bits (305), Expect = 2e-27
Identities = 83/272 (30%), Positives = 137/272 (49%), Gaps = 17/272 (6%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
++T QD+ +G+GS+ T YK D+STG+LFA K + + E K + E + L
Sbjct: 13 QKTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDEL-DEAKCDALVSEISVLR 71
Query: 64 LLAHGNHPGIIKLYYTF--HDSENLYFVLDFAPXXXXXX----XXXXXXRFNEAWTKHFM 117
L HP I++ Y+ +++++Y V++ RF E + +
Sbjct: 72 QL---QHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVL 128
Query: 118 CQLIDALEYIHGC----KVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSF 173
QL AL+ H ++HRD+KP N+ L + G + DFG+A L + ++ SF
Sbjct: 129 FQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGLARMLRRDQSFAA--SF 186
Query: 174 VGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWI 233
VGT Y+SPEL+ K + SD+WAVGC++Y+ PPFRG EKI ++ I
Sbjct: 187 VGTPHYMSPELVKGRKYDRKSDVWAVGCLVYEMCALRPPFRGRAFDQLSEKIAQGEFSRI 246
Query: 234 YMV-SQHITDLVSKILVLDPDSRYTLPQIKNH 264
+ S + ++++ +L +D + R + I H
Sbjct: 247 PAIYSTDLQEIIAFMLAVDHEQRPGIEVIIRH 278
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 121 bits (304), Expect = 3e-27
Identities = 82/270 (30%), Positives = 132/270 (48%), Gaps = 22/270 (8%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
+G G+++ V + R T Q +A+K+ K + K K ++ L ++ +HP I+K
Sbjct: 290 IGDGNFAVVKECRHRETRQAYAMKIIDKSRL----KGKEDMVDSEIL-IIQSLSHPNIVK 344
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ + +Y +L++ +F E + L AL ++H +VHR
Sbjct: 345 LHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHR 404
Query: 136 DLKPENLLLS-SEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSN 191
DLKPENLL+ +E K L + DFG+A ++ + + GT YV+PE+L +
Sbjct: 405 DLKPENLLVQRNEDKSTTLKLADFGLAKHV-----VRPIFTVCGTPTYVAPEILSEKGYG 459
Query: 192 FCSDIWAVGCMLYQFTQGTPPFRG-ENELAAFEKIVNLDYHWIYM------VSQHITDLV 244
D+WA G +LY G PPFR E + I+ L H+ ++ +S DLV
Sbjct: 460 LEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLG-HFEFLPPYWDNISDAAKDLV 518
Query: 245 SKILVLDPDSRYTLPQIKNHAWFQGIDWTN 274
S++LV+DP RYT Q+ H W + TN
Sbjct: 519 SRLLVVDPKKRYTAHQVLQHPWIETAGKTN 548
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 121 bits (304), Expect = 3e-27
Identities = 81/269 (30%), Positives = 124/269 (45%), Gaps = 17/269 (6%)
Query: 13 KERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVK-YVTIE--KNTLNLLAHG- 68
KE LG G STV + +++ TG+ FA K+ + Y +E + +++L
Sbjct: 26 KEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVM 85
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP II L F ++ V + P +E T+ M Q+ + +EYIH
Sbjct: 86 GHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIH 145
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+VHRDLKPEN+LL + ITDFG A L + L ++ GT Y++PE L N
Sbjct: 146 AKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKL---TNLCGTPGYLAPETLKCN 202
Query: 189 KSNFCS------DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYM----VSQ 238
DIWA G +++ G PPF ++ I+ Y + +S+
Sbjct: 203 MFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISE 262
Query: 239 HITDLVSKILVLDPDSRYTLPQIKNHAWF 267
DL+ K LV+DP R T+ ++ H +F
Sbjct: 263 DPKDLIRKCLVVDPSQRITVKEVLRHPFF 291
>7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 755
Score = 121 bits (304), Expect = 3e-27
Identities = 65/167 (38%), Positives = 95/167 (55%), Gaps = 2/167 (1%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
+R+P DF F +G GSYS VY AVD + + +AIKVC K+ I+ E K Y+ E+ ++
Sbjct: 159 RRSPNDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMH 218
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
+ N PG + L TF D +LYFV+ +A F+ A T+H+ +L+ A
Sbjct: 219 QMT--NVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLA 276
Query: 124 LEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSST 170
E++H VVHRDLKPEN+LL + +I DFG A + A + +T
Sbjct: 277 CEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALAT 323
Score = 85.1 bits (209), Expect = 3e-16
Identities = 44/114 (38%), Positives = 63/114 (54%), Gaps = 7/114 (6%)
Query: 166 NLSSTSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKI 225
N +SFVGTA+YVSPE+L +D+WA+GC++YQ G PPFRG N+ F++I
Sbjct: 382 NRHRKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEI 441
Query: 226 VNLDYHWIYMVSQHITDLVSKILVLDPDSRY-------TLPQIKNHAWFQGIDW 272
++ + + DLV K+L +DP R I+ H +F GIDW
Sbjct: 442 LDCAVDFPQGFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDW 495
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 121 bits (303), Expect = 4e-27
Identities = 80/278 (28%), Positives = 136/278 (48%), Gaps = 17/278 (6%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T +FS +G G + VY TG+++A+K KK I + E+ L+L+
Sbjct: 187 TMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLV 246
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
+ G+ P I+ + Y FH + L F+LD F+E + + ++I LE
Sbjct: 247 STGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLE 306
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
++H VV+RDLKP N+LL G I+D G+A + + +S VGT Y++PE+L
Sbjct: 307 HVHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHAS----VGTHGYMAPEVL 362
Query: 186 LQNKSNFCSDIW-AVGCMLYQFTQGTPPFR-----GENELAAFEKIVNLDYHWIYMVSQH 239
+ + S W ++GCML++ +G PFR ++E+ VN++ + S
Sbjct: 363 QKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTF--SPE 420
Query: 240 ITDLVSKILVLDPDSRYTL-----PQIKNHAWFQGIDW 272
+ L+ +L D R ++K H++F+G+DW
Sbjct: 421 LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDW 458
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 121 bits (303), Expect = 4e-27
Identities = 84/311 (27%), Positives = 139/311 (44%), Gaps = 56/311 (18%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G++ V A T L+A+K KK +++ N+V +V E++ +LA ++ ++K
Sbjct: 674 LGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERD---ILAEADNEWVVK 730
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
LYY+F D ++LYFV+D+ P F E + ++ +L A+E +H +HR
Sbjct: 731 LYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHR 790
Query: 136 DLKPENLLLSSEGKLMITDFGV--------------------------------ASNLAA 163
D+KP+N+L+ +G + +TDFG+ SN
Sbjct: 791 DIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRC 850
Query: 164 TDNLSS-------------TSSFVGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGT 210
D L + S VGT Y++PE+LL+ D W+VG +L++ G
Sbjct: 851 GDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQ 910
Query: 211 PPFRGENELAAFEKIVN----LDYHWIYMVSQHITDLVSKILVLDPD---SRYTLPQIKN 263
PPF K++N L +S DL++K L D R +K
Sbjct: 911 PPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITK-LCCSADHRLGRNGADDLKA 969
Query: 264 HAWFQGIDWTN 274
H +F ID+++
Sbjct: 970 HPFFSAIDFSS 980
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 121 bits (303), Expect = 4e-27
Identities = 73/256 (28%), Positives = 125/256 (48%), Gaps = 7/256 (2%)
Query: 14 ERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGI 73
E +G GS+ VYK + + Q+ A+K K SE +++ + E + ++ HP I
Sbjct: 8 EMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGR-SEKELRNLQRE---IEIMRGLRHPNI 63
Query: 74 IKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVV 133
+ + +F + + V D+A + E + QL+ AL Y+H +++
Sbjct: 64 VHMLDSFETDKEVVVVTDYAEGELFQILEDDG-KLPEDQVQAIAAQLVSALYYLHSHRIL 122
Query: 134 HRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
HRD+KP+N+LL+ G + + DFG A A + N +S GT Y+SPEL+ + +
Sbjct: 123 HRDMKPQNILLAKGGGIKLCDFGFAR--AMSTNTMVLTSIKGTPLYMSPELVEERPYDHT 180
Query: 194 SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPD 253
+D+W+VGC+LY+ GTPPF + I+ W +S + + +L DP
Sbjct: 181 ADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPR 240
Query: 254 SRYTLPQIKNHAWFQG 269
R + P + H + G
Sbjct: 241 QRLSWPDLLYHPFIAG 256
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 121 bits (303), Expect = 4e-27
Identities = 78/261 (29%), Positives = 122/261 (45%), Gaps = 17/261 (6%)
Query: 30 RSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN------------LLAHGNHPGIIKLY 77
R+ G+ + KV +HI++ +V I+K LN ++ NHP I+KL+
Sbjct: 63 RTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLF 122
Query: 78 YTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHRDL 137
+ LY V+++A R E + Q++ A+ Y H +VHRDL
Sbjct: 123 EVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDL 182
Query: 138 KPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCS-DI 196
K ENLLL +E + I DFG ++ L +F G+ Y +PEL K + DI
Sbjct: 183 KAENLLLDAEANIKIADFGFSNEFTLGSKL---DTFCGSPPYAAPELFQGKKYDGPEVDI 239
Query: 197 WAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSRY 256
W++G +LY G+ PF G N E+++ Y + +S ++ + LVL+P R
Sbjct: 240 WSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRC 299
Query: 257 TLPQIKNHAWFQGIDWTNKEL 277
TL QI W I + +EL
Sbjct: 300 TLEQIMKDKWI-NIGYEGEEL 319
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 121 bits (303), Expect = 4e-27
Identities = 83/294 (28%), Positives = 144/294 (48%), Gaps = 24/294 (8%)
Query: 2 SRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNT 61
+R DF + +G+Y VY R T Q FA+K +K+ ++ N+V V E++
Sbjct: 350 NRAPCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDI 409
Query: 62 LNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLI 121
L + ++P ++ Y +F + L ++++ + ++ + I
Sbjct: 410 LTM---ADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETI 466
Query: 122 DALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA-------SNLAAT--DNLSSTSS 172
A+EY+H +VHRDLKP+NLL+++ G + +TDFG++ + L A D + T
Sbjct: 467 LAIEYLHSYGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQ 526
Query: 173 F-----VGTAEYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN 227
F GT EY++PE++L+ D WA+G +LY+F G PF GE A F K+++
Sbjct: 527 FQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVIS 586
Query: 228 LDYHW---IYMVSQHITDLVSKILVLDPDSRY-TL---PQIKNHAWFQGIDWTN 274
D + + DL ++L +P R TL Q+ H +F +D+T+
Sbjct: 587 EDVEYPEEDEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDFTS 640
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 121 bits (303), Expect = 4e-27
Identities = 78/252 (30%), Positives = 119/252 (46%), Gaps = 8/252 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ V A+ TG+ AIKV K + + + K E + LL NHP I++
Sbjct: 104 LGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYR-EVKIMKLL---NHPNIVR 159
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ LY V+++A R E + QL+ A++Y H VVHR
Sbjct: 160 LFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHR 219
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK-SNFCS 194
DLK ENLLL + I DFG + D + +F G+ Y +PEL + K +
Sbjct: 220 DLKAENLLLDQHMNIKIADFGFGNTF---DPNAQLETFCGSPPYAAPELFMGRKYAGPEV 276
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
D W++G +LY G+ PF G E+++ Y Y +S +L+ K LVL+P
Sbjct: 277 DAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDCENLMRKFLVLNPAK 336
Query: 255 RYTLPQIKNHAW 266
R +L + + W
Sbjct: 337 RTSLSAVMSDKW 348
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 120 bits (302), Expect = 5e-27
Identities = 74/263 (28%), Positives = 131/263 (49%), Gaps = 12/263 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ K+ +G GSY VYKA+++ T Q+ AIK ++ EN + I ++LL + N
Sbjct: 25 YHLKQVIGRGSYGVVYKAINKHTDQVVAIK-----EVVYENDEELNDIMAE-ISLLKNLN 78
Query: 70 HPGIIKLYYTFHDSENLYFVLDF-APXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
H I+K + S LY +L++ A +E +K ++ Q + L+Y+H
Sbjct: 79 HNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLH 138
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
G V+HRD+K N+LLS++ + + DFGV++ + SS + GT +++PE+L
Sbjct: 139 GEGVIHRDIKAANILLSADNTVKLADFGVSTIVN-----SSALTLAGTLNWMAPEILGNR 193
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
++ SDIW++G + + PP+ + + + N Y+ S+ + D +SK
Sbjct: 194 GASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCF 253
Query: 249 VLDPDSRYTLPQIKNHAWFQGID 271
V + R T Q+ H W +
Sbjct: 254 VKNMYKRPTADQLLKHVWINSTE 276
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 120 bits (302), Expect = 5e-27
Identities = 80/270 (29%), Positives = 133/270 (48%), Gaps = 15/270 (5%)
Query: 5 RTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNL 64
R +++ E LG G++S V + V GQ +A K+ + K + + + K + E L
Sbjct: 8 RFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQK-LEREARICRL 66
Query: 65 LAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDAL 124
L HP I++L+ + + + Y + D ++EA H + Q+++A+
Sbjct: 67 L---KHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAV 123
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
+ H VVHRDLKPENLLL+S+ K + + DFG+A + + F GT Y+S
Sbjct: 124 LHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLA--IEVEGEQQAWFGFAGTPGYLS 181
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY-----HWIYMV 236
PE+L ++ D+WA G +LY G PPF E++ +++I Y W V
Sbjct: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW-DTV 240
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAW 266
+ DL++K+L ++P R T + H W
Sbjct: 241 TPEAKDLINKMLTINPSKRITAAEALKHPW 270
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 120 bits (302), Expect = 5e-27
Identities = 77/269 (28%), Positives = 126/269 (46%), Gaps = 8/269 (2%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ ++ LG G V TG+ AIK+ +K+ + SE+ ++ V E + L+
Sbjct: 47 YKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKL-SESVLQKVEREIAIMKLI---E 102
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP ++ LY + + + LY +L+ R + F Q+I AL++ H
Sbjct: 103 HPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHA 162
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+ HRDLKPENLLL + + DFG+AS L ++ TS G+ Y PE++ K
Sbjct: 163 HNICHRDLKPENLLLDERNNIKVADFGMAS-LQVEGSMLETS--CGSPHYACPEVIRGEK 219
Query: 190 -SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+D+W+ G +LY G PF +N EK+ +H + V + L+ ++
Sbjct: 220 YDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLLRAMI 279
Query: 249 VLDPDSRYTLPQIKNHAWFQGIDWTNKEL 277
+DP RY+L + H W G + EL
Sbjct: 280 EVDPGKRYSLADVFKHPWVSGTTKADPEL 308
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 120 bits (302), Expect = 5e-27
Identities = 84/311 (27%), Positives = 138/311 (44%), Gaps = 43/311 (13%)
Query: 1 MSRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
M R+ +F ++ G+Y VYKA D T ++ A+K K E + +
Sbjct: 288 MFGSRSVNEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLR 347
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSEN---LYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFM 117
+N+L NHP I+ + +N +Y V++ F+ + K M
Sbjct: 348 EINILLSCNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLM 407
Query: 118 CQLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTA 177
QL+D L+Y+H ++HRDLKP NLL+++ G+L I DFG+A + + + V T
Sbjct: 408 MQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSP--IKPYTQMVITQ 465
Query: 178 EYVSPELLLQNKS-NFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNL-------- 228
Y PELLL K + D+W+VGC++ + P F G++EL +KI +
Sbjct: 466 WYRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAI 525
Query: 229 -----------------DYHWI------------YMVSQHITDLVSKILVLDPDSRYTLP 259
Y+ + ++S+ DL++ +L LDP+ R T+
Sbjct: 526 WPGFSSFPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVE 585
Query: 260 QIKNHAWFQGI 270
NH WF +
Sbjct: 586 DALNHGWFHEV 596
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 120 bits (302), Expect = 5e-27
Identities = 76/275 (27%), Positives = 132/275 (47%), Gaps = 14/275 (5%)
Query: 3 RKRTPQ------DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVT 56
RK TP ++ LG GS++ V A + TG AIK+ ++ + V+ +
Sbjct: 6 RKATPASRTRVGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLK 65
Query: 57 IEKNTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHF 116
E +T+ L+ HP ++++ +Y VL+ R E + +
Sbjct: 66 REISTMKLI---KHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRY 122
Query: 117 MCQLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFV 174
QLI+A++Y H V HRDLKPENL+L + G L ++DFG++ S D L T+
Sbjct: 123 FQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTA--C 180
Query: 175 GTAEYVSPELLL-QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWI 233
GT YV+PE+L + +D+W+ G +L+ G PF N + +++I ++
Sbjct: 181 GTPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCP 240
Query: 234 YMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQ 268
SQ ++ +IL +P +R ++ ++ WF+
Sbjct: 241 PWFSQGAKRVIKRILEPNPITRISIAELLEDEWFK 275
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 120 bits (301), Expect = 6e-27
Identities = 77/262 (29%), Positives = 124/262 (46%), Gaps = 9/262 (3%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
+F KE +G G++ V + TG AIK+ ++ + V E + L L H
Sbjct: 23 NFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTH- 81
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
P I +L+ +++ V++ ++ + Q+I + Y H
Sbjct: 82 --PHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCH 139
Query: 129 GCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQN 188
+VHRDLKPENLLL + + I DFG+++ + D LS+ G+ Y +PEL+ N
Sbjct: 140 NHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTAC---GSPNYAAPELI-SN 195
Query: 189 KSNFCS--DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSK 246
K D+W+ G +LY GT PF +N F KI + Y Y + + DL+S
Sbjct: 196 KLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLIST 255
Query: 247 ILVLDPDSRYTLPQIKNHAWFQ 268
+L +DP R + +I NH+WF+
Sbjct: 256 MLQVDPVKRADVKRIVNHSWFR 277
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 120 bits (300), Expect = 8e-27
Identities = 72/265 (27%), Positives = 135/265 (50%), Gaps = 14/265 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K+ + F E+LG GSY +VYKA+ + TGQ+ AIK + E+ ++ + E ++
Sbjct: 24 KQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIK-----QVPVESDLQEIIKE---IS 75
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMCQLID 122
++ + P ++K Y ++ + +L+ V+++ + E + +
Sbjct: 76 IMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLK 135
Query: 123 ALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSP 182
LEY+H + +HRD+K N+LL++EG + DFGVA L TD ++ ++ +GT +++P
Sbjct: 136 GLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQL--TDTMAKRNTVIGTPFWMAP 193
Query: 183 ELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN---LDYHWIYMVSQH 239
E++ + N +DIW++G + +G PP+ + + A I + + S +
Sbjct: 194 EVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDN 253
Query: 240 ITDLVSKILVLDPDSRYTLPQIKNH 264
TD V + LV P+ R T Q+ H
Sbjct: 254 FTDFVKQCLVKSPEQRATATQLLQH 278
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 120 bits (300), Expect = 8e-27
Identities = 74/268 (27%), Positives = 138/268 (50%), Gaps = 14/268 (5%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+++ VY T Q AIK+ K+ ++ ++ + K ++++ HP +++
Sbjct: 18 LGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQI---KREISVMRIARHPNVVE 74
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
LY +YFV+++ ++ K+F QLI+A+++ H +V HR
Sbjct: 75 LYEVMATKTRIYFVMEYCKGGELFNKVAKGKLRDDVAWKYFY-QLINAVDFCHSREVYHR 133
Query: 136 DLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNF- 192
D+KPENLLL L ++DFG++ ++ D L T+ GT YV+PE++ N+ +
Sbjct: 134 DIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTT--CGTPAYVAPEVI--NRKGYD 189
Query: 193 --CSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVL 250
+DIW+ G +L+ G PF N + + KI D+ + + L+ K+L
Sbjct: 190 GTKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRLLCKMLDP 249
Query: 251 DPDSRYTLPQIKNHAWF-QGIDWTNKEL 277
+P++R T+ +I+ +WF +G+ K++
Sbjct: 250 NPETRITIARIRESSWFRKGLHMKQKKM 277
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 120 bits (300), Expect = 8e-27
Identities = 81/261 (31%), Positives = 130/261 (49%), Gaps = 12/261 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
+G G+++ VY +TGQ AIKV SK+ + + E ++ L HP I++
Sbjct: 28 VGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRL---RHPSIVR 84
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ ++FV++FA RF E ++ + QLI A+ Y H + HR
Sbjct: 85 LFEVLATKSKIFFVMEFAKGGELFAKVSKG-RFCEDLSRRYFQQLISAVGYCHSRGIFHR 143
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTS---SFVGTAEYVSPELLLQNKSNF 192
DLKPENLLL + L I+DFG++ A TD + + GT YV+PE+L + +
Sbjct: 144 DLKPENLLLDEKLDLKISDFGLS---ALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDG 200
Query: 193 CS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLD 251
DIW+ G +L+ G PF N + + KI ++ S + L++++L +
Sbjct: 201 AKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDLRRLLTRLLDTN 260
Query: 252 PDSRYTLPQIKNHAWF-QGID 271
P +R T+ +I + WF QG D
Sbjct: 261 PQTRITIEEIIHDPWFKQGYD 281
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 120 bits (300), Expect = 8e-27
Identities = 83/256 (32%), Positives = 121/256 (46%), Gaps = 8/256 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G+ + V A+D TG+ FAIK+ K I N + E TL +L HP I++
Sbjct: 17 LGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVL---KHPNIVR 73
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L+ +Y VL+ + +E + QLID + Y H V HR
Sbjct: 74 LHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKGVFHR 133
Query: 136 DLKPENLLLSSEGKLMITDFGVA--SNLAATDNLSSTSSFVGTAEYVSPELLL-QNKSNF 192
DLK EN+LL ++G + ITDFG++ S D L T+ G+ YV+PE+L +
Sbjct: 134 DLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTT--CGSPNYVAPEVLANEGYDGA 191
Query: 193 CSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDP 252
SDIW+ G +LY G PF N KI D +S ++ ++L +P
Sbjct: 192 ASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPPIPRWISLGAKTMIKRMLDPNP 251
Query: 253 DSRYTLPQIKNHAWFQ 268
+R T+ IK H WF+
Sbjct: 252 VTRVTIAGIKAHDWFK 267
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 120 bits (300), Expect = 8e-27
Identities = 74/258 (28%), Positives = 123/258 (46%), Gaps = 8/258 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ + +G G+++ V A R T AIK+ K + N K + ++
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVY----REVEIMKRLK 196
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP IIKLY +Y V ++A R +E+ + Q+I A+EY H
Sbjct: 197 HPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHK 256
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+VHRDLK ENLLL + I DFG +++ + L +++ G+ Y +PE+ +
Sbjct: 257 KGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELL---ATWCGSPPYAAPEVFEGKQ 313
Query: 190 SNFCS-DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
DIW++G +LY G PF G + +++++ + + +S L+ ++L
Sbjct: 314 YTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRML 373
Query: 249 VLDPDSRYTLPQIKNHAW 266
VL+P RYT+ QIK H W
Sbjct: 374 VLEPTRRYTIDQIKRHRW 391
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 119 bits (299), Expect = 1e-26
Identities = 74/276 (26%), Positives = 138/276 (49%), Gaps = 17/276 (6%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+D+ + +G G++ V +++ +++A+K+ SK +I + + E++ ++A
Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERD---IMAF 146
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
N P +++L+Y F D LY V+++ P E W K + +++ AL+ I
Sbjct: 147 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWAKFYTAEVVLALDAI 205
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL-L 186
H ++HRD+KP+N+LL G L + DFG + T + + VGT +Y+SPE+L
Sbjct: 206 HSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDET-GMVHCDTAVGTPDYISPEVLKS 264
Query: 187 QNKSNFCS---DIWAVGCMLYQFTQGTPPFRGENELAAFEKIV----NLDYHWIYMVSQH 239
Q F D W+VG LY+ G PF ++ + + KI+ +L + +S+H
Sbjct: 265 QGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKH 324
Query: 240 ITDLVSKILVLDPD---SRYTLPQIKNHAWFQGIDW 272
+L+ L D + R + +I+ H +F+ W
Sbjct: 325 AKNLICAFLT-DREVRLGRNGVEEIRQHPFFKNDQW 359
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 119 bits (299), Expect = 1e-26
Identities = 74/276 (26%), Positives = 138/276 (49%), Gaps = 17/276 (6%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+D+ + +G G++ V +++ +++A+K+ SK +I + + E++ ++A
Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERD---IMAF 146
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
N P +++L+Y F D LY V+++ P E W K + +++ AL+ I
Sbjct: 147 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWAKFYTAEVVLALDAI 205
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL-L 186
H ++HRD+KP+N+LL G L + DFG + T + + VGT +Y+SPE+L
Sbjct: 206 HSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDET-GMVHCDTAVGTPDYISPEVLKS 264
Query: 187 QNKSNFCS---DIWAVGCMLYQFTQGTPPFRGENELAAFEKIV----NLDYHWIYMVSQH 239
Q F D W+VG LY+ G PF ++ + + KI+ +L + +S+H
Sbjct: 265 QGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKH 324
Query: 240 ITDLVSKILVLDPD---SRYTLPQIKNHAWFQGIDW 272
+L+ L D + R + +I+ H +F+ W
Sbjct: 325 AKNLICAFLT-DREVRLGRNGVEEIRQHPFFKNDQW 359
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 119 bits (299), Expect = 1e-26
Identities = 76/266 (28%), Positives = 128/266 (47%), Gaps = 13/266 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+S +LG G + T + V+++TG+ FA K +K+ ++++ V+ V E ++ LA
Sbjct: 150 YSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLA--G 207
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP +I + + D ++ V++ + E ++ +E H
Sbjct: 208 HPNVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHS 267
Query: 130 CKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
V+HRDLKPEN L S + L DFG++ D + VG+ YV+PE +L
Sbjct: 268 LGVMHRDLKPENFLFVSKHEDSLLKTIDFGLSMFFKPDDVFTDV---VGSPYYVAPE-VL 323
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY----MVSQHITD 242
+ + +D+W+ G ++Y G PPF E E FE++++ D + +S+ D
Sbjct: 324 RKRYGPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKD 383
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQ 268
LV K+LV DP R T Q+ H W Q
Sbjct: 384 LVRKMLVRDPKKRLTAHQVLCHPWVQ 409
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 119 bits (299), Expect = 1e-26
Identities = 66/276 (23%), Positives = 134/276 (47%), Gaps = 16/276 (5%)
Query: 1 MSRKRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKN 60
+S++ + E +G G++ V++ +RSTG +FA K H + ++ ++
Sbjct: 6129 ISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGNIFAAKFIPVSHSVEKDLIR------R 6182
Query: 61 TLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMCQ 119
++++ +H +I L+ F D + + +L+F EA ++M Q
Sbjct: 6183 EIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTEAEVINYMRQ 6242
Query: 120 LIDALEYIHGCKVVHRDLKPENLLLS--SEGKLMITDFGVASNLAATDNLSSTSSFVGTA 177
+ + + ++H ++H D+KPEN++ S + + DFG+A+ L + + T+ GTA
Sbjct: 6243 ICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKITT---GTA 6299
Query: 178 EYVSPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHW----I 233
E+ +PE++ + F +D+WA G + Y G PF G+N++ + + D+ +
Sbjct: 6300 EFAAPEIVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESF 6359
Query: 234 YMVSQHITDLVSKILVLDPDSRYTLPQIKNHAWFQG 269
+S+ D + K+LV + + R T + H W G
Sbjct: 6360 KYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTG 6395
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 119 bits (299), Expect = 1e-26
Identities = 80/283 (28%), Positives = 138/283 (48%), Gaps = 22/283 (7%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
DF + +G G++ V ST +++A+K+ +K ++ + E++ +L G
Sbjct: 99 DFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERD---VLVFG 155
Query: 69 NHPGIIKLYYTFHDSENLYFVLDF-APXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
+ I L+Y F D+ NLY V+D+ + E K ++ ++I A+ I
Sbjct: 156 DRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSI 215
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL- 186
H + VHRD+KP+N+LL G + + DFG L + S + VGT +Y+SPE+L
Sbjct: 216 HQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVA-VGTPDYISPEILRA 274
Query: 187 --QNKSNFCS--DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHW--------IY 234
K + + D W++G +Y+ G PF E+ + + KI+N + Y
Sbjct: 275 MEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNY 334
Query: 235 MVSQHITDLVSKILVLDPDSRY---TLPQIKNHAWFQGIDWTN 274
VS+ DL+ K++ + P++R + +H WF GIDW N
Sbjct: 335 KVSETSQDLLCKLICI-PENRLGQNGIQDFMDHPWFVGIDWKN 376
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 119 bits (298), Expect = 1e-26
Identities = 67/252 (26%), Positives = 122/252 (47%), Gaps = 5/252 (1%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G ++ Y+A D TG +A+KV + + ++ + + N + L H I++
Sbjct: 29 LGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKIL---NEIELHRDLQHRHIVR 85
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
+ F D++N+Y L+ E ++++ Q++ L+Y+H ++HR
Sbjct: 86 FSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHR 145
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLK N ++ +L + DFG+A+ L + T GT YV+PE+LL+ +D
Sbjct: 146 DLKLGNFFITENMELKVGDFGLAARLEPPEQRKKT--ICGTPNYVAPEVLLRQGHGPEAD 203
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSR 255
+W++GC++Y G+PPF + + I + Y +S L++ IL P R
Sbjct: 204 VWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDR 263
Query: 256 YTLPQIKNHAWF 267
++ QI H +F
Sbjct: 264 PSIDQILRHDFF 275
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 119 bits (298), Expect = 1e-26
Identities = 93/354 (26%), Positives = 164/354 (46%), Gaps = 37/354 (10%)
Query: 5 RTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNL 64
R ++ E LG G++S V + + TGQ +A K+ + K + + + K + E L
Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQK-LEREARICRL 67
Query: 65 LAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDAL 124
L HP I++L+ + + Y V D ++EA H + Q+++++
Sbjct: 68 L---KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESV 124
Query: 125 EYIHGCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVS 181
+ H +VHRDLKPENLLL+S+ K + + DFG+A + + + F GT Y+S
Sbjct: 125 NHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA--IEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDY-----HWIYMV 236
PE+L ++ D+WA G +LY G PPF E++ +++I Y W V
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEW-DTV 241
Query: 237 SQHITDLVSKILVLDPDSRYTLPQIKNHAWF-------------QGIDWTNK-----ELI 278
+ DL++K+L ++P R T + H W + +D K +L
Sbjct: 242 TPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLK 301
Query: 279 WKGIWQLFGNRNHNN----FNGPSMMNKQLHVIDTTIKNIPIQPRKRKPMKVTQ 328
+ + RN + P + + +TTI++ ++ RK++ +KVT+
Sbjct: 302 GAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTE 355
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 119 bits (298), Expect = 1e-26
Identities = 76/255 (29%), Positives = 129/255 (49%), Gaps = 9/255 (3%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
+G G+++ V D + G A+K+ K +I + V E T+ LL NHP I++
Sbjct: 18 IGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLL---NHPNIVQ 74
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
++ + V+++ + E+ + QLIDA++Y H V HR
Sbjct: 75 IHEVIGTKTKICIVMEYV-SGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNRGVYHR 133
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QNKSNFCS 194
DLKP+NLLL S+G L ++DFG+++ + D LS+ G+ Y++PEL++ + S
Sbjct: 134 DLKPQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTA---CGSPCYIAPELIMNKGYSGAAV 190
Query: 195 DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDS 254
D+W+ G +L++ G PPF ++KI+ DY + + L+ IL +P S
Sbjct: 191 DVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDPNPLS 250
Query: 255 RYTLPQ-IKNHAWFQ 268
R TL + I +WF+
Sbjct: 251 RITLAEIIIKDSWFK 265
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 119 bits (298), Expect = 1e-26
Identities = 71/259 (27%), Positives = 131/259 (50%), Gaps = 5/259 (1%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIK-VCSKKHIISENKVK-YVTIEKNTLNLLAHGNHPGI 73
+G G++ TVY ++ +G+L A+K V + S+ K + ++ + + LL + +HP I
Sbjct: 75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNI 134
Query: 74 IKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVV 133
++ T + + L +L+F P F E+ + + QL+ LEY+H ++
Sbjct: 135 VRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIM 194
Query: 134 HRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFC 193
HRD+K N+L+ ++G + + DFG + +A ++ S GT +++PE++LQ +F
Sbjct: 195 HRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFS 254
Query: 194 SDIWAVGCMLYQFTQGTPPFRGE-NELAAFEKIVNLDYHWIY--MVSQHITDLVSKILVL 250
+DIW+VGC + + G P+ + E+AA I H +S D + K L
Sbjct: 255 ADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQE 314
Query: 251 DPDSRYTLPQIKNHAWFQG 269
P+ R T ++ H + G
Sbjct: 315 VPNLRPTASELLKHPFVMG 333
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 119 bits (297), Expect = 2e-26
Identities = 73/264 (27%), Positives = 129/264 (48%), Gaps = 14/264 (5%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ K +G GS+S V + ++T + FAIKV + E + + + + L++L +
Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETR----EREGREACVSE--LSVLRRVS 116
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
H I++L F + +Y V++ A F E + + D + Y+H
Sbjct: 117 HRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHA 176
Query: 130 CKVVHRDLKPENLLL---SSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
++ HR+LKPENLL E K++ITDFG+A + + + + + GT EY++PE+LL
Sbjct: 177 LQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDW-TMKTLCGTPEYIAPEVLL 235
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWI----YMVSQHITD 242
+ D+WA+G + Y G PF E++ + KI+ Y++ +S D
Sbjct: 236 RKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKD 295
Query: 243 LVSKILVLDPDSRYTLPQIKNHAW 266
+ K+L+L+ R + Q +H W
Sbjct: 296 FIDKLLILEAGHRMSAGQALDHPW 319
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 119 bits (297), Expect = 2e-26
Identities = 76/266 (28%), Positives = 126/266 (46%), Gaps = 13/266 (4%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+S +LG G + T + +++ TG +A K SK+ ++++ V+ V E ++ LA
Sbjct: 186 YSLGRKLGQGQFGTTFLCLEKGTGNEYACKSISKRKLLTDEDVEDVRREIQIMHHLA--G 243
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP +I + + D ++ V++ + E ++ LE H
Sbjct: 244 HPNVISIKGAYEDVVAVHLVMELCSGGELFDRIIQRGHYTERKAAELARTIVGVLEACHS 303
Query: 130 CKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
V+HRDLKPEN L S + L DFG++ + + VG+ YV+PE +L
Sbjct: 304 LGVMHRDLKPENFLFVSREEDSLLKTIDFGLSMFFKPDEVFTDV---VGSPYYVAPE-VL 359
Query: 187 QNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIY----MVSQHITD 242
+ + SD+W+ G ++Y G PPF E E FE++++ D + +S+ D
Sbjct: 360 RKRYGPESDVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKD 419
Query: 243 LVSKILVLDPDSRYTLPQIKNHAWFQ 268
LV K+LV DP R T Q+ H W Q
Sbjct: 420 LVRKMLVRDPKRRLTAHQVLCHPWVQ 445
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 119 bits (297), Expect = 2e-26
Identities = 74/267 (27%), Positives = 125/267 (46%), Gaps = 10/267 (3%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ ++ +G G+++ V A + T AIK+ K + E Y+ + +L
Sbjct: 41 YELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEE----YLNKTFREIAILKSLR 96
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP I +LY +Y V ++AP R E QL+ A+ Y H
Sbjct: 97 HPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHR 156
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QN 188
VVHRDLK EN+LL + + + DFG +++ + ++ ++ G+ Y +PE+
Sbjct: 157 RGVVHRDLKAENVLLDKDMNIKLADFGFSNHY---EEGATLKTWCGSPPYAAPEVFQGLE 213
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
SDIW++G +LY G PF G+ L ++V + + +SQ L+ +L
Sbjct: 214 YDGPKSDIWSLGVVLYALVCGALPFDGKTILELKSRVVLGKFRIPFFMSQECEQLIRNML 273
Query: 249 VLDPDSRYTLPQIKNHAWFQGIDWTNK 275
V++PD RYT+ QI H W +W ++
Sbjct: 274 VVEPDRRYTIKQIIKHRWLS--EWQSE 298
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 119 bits (297), Expect = 2e-26
Identities = 71/260 (27%), Positives = 125/260 (47%), Gaps = 7/260 (2%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
++ +G GS+ VYKA + ++ AIKV SK+ K + + ++ A
Sbjct: 4 YAVSSMVGQGSFGCVYKATRKDDSKVVAIKVISKRG----RATKELKNLRRECDIQARLK 59
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP +I++ +F +L+ V +FA E + L+ AL Y+H
Sbjct: 60 HPHVIEMIESFESKTDLFVVTEFA-LMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHS 118
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
+++HRDLKP+N+LL + DFG+A N+ ++ +S GT Y++PELL +
Sbjct: 119 NRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHV--LTSIKGTPLYMAPELLAEQP 176
Query: 190 SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILV 249
+ +D+W++GC+ Y+ G PPF + L + I + D W ++ + +L
Sbjct: 177 YDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLE 236
Query: 250 LDPDSRYTLPQIKNHAWFQG 269
DP R + Q+ H + +G
Sbjct: 237 KDPGLRISWTQLLCHPFVEG 256
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 118 bits (296), Expect = 2e-26
Identities = 76/273 (27%), Positives = 129/273 (46%), Gaps = 14/273 (5%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ E +G G ++ V A TG++ AIK+ K + S+ + K + L +
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD-----LPRIKTEIEALKNLR 65
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
H I +LY+ + ++ VL++ P R +E T+ Q++ A+ Y+H
Sbjct: 66 HQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHS 125
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNK 189
HRDLKPENLL KL + DFG+ + + + G+ Y +PE L+Q K
Sbjct: 126 QGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDY-HLQTCCGSLAYAAPE-LIQGK 183
Query: 190 SNFCS--DIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKI 247
S S D+W++G +LY G PF +N +A ++KI+ Y +S L+ ++
Sbjct: 184 SYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQM 243
Query: 248 LVLDPDSRYTLPQIKNHAWFQ-----GIDWTNK 275
L +DP R ++ + NH W ++W +K
Sbjct: 244 LQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSK 276
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 118 bits (296), Expect = 2e-26
Identities = 75/260 (28%), Positives = 128/260 (48%), Gaps = 7/260 (2%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ KE LG G++ V + +T A+K+ +++ I S + V + E L+L
Sbjct: 25 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLF---R 81
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II+LY +++ +++ R A + F Q+I ++Y H
Sbjct: 82 HPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHR 141
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QN 188
VVHRDLKPENLLL + + I DFG+++ + D L ++ G+ Y +PE++ +
Sbjct: 142 HMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTS---CGSPNYAAPEVISGKL 198
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ D+W+ G +LY GT PF E+ + F KI + + + + I +L+ +L
Sbjct: 199 YAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHML 258
Query: 249 VLDPDSRYTLPQIKNHAWFQ 268
+DP R T+ + H WFQ
Sbjct: 259 CVDPMKRATIKDVIAHEWFQ 278
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 118 bits (296), Expect = 2e-26
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 9 DFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHG 68
++ KE LG G++S V + V ++TG FA K+ + K + + + K + +
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKL----EREARICRKL 66
Query: 69 NHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIH 128
HP I++L+ + + Y V D ++EA H + Q+++++ Y H
Sbjct: 67 QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCH 126
Query: 129 GCKVVHRDLKPENLLLSSEGK---LMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELL 185
+VHRDLKPENLLL+S+ K + + DFG+A + ++ + F GT Y+SPE+L
Sbjct: 127 SNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEV---NDSEAWHGFAGTPGYLSPEVL 183
Query: 186 LQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDY---HWIYMVSQHI 240
++ + DIWA G +LY G PPF E++ L A K DY W V+
Sbjct: 184 KKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW-DTVTPEA 242
Query: 241 TDLVSKILVLDPDSRYTLPQIKNHAW 266
L+ +L ++P R T Q W
Sbjct: 243 KSLIDSMLTVNPKKRITADQALKVPW 268
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 118 bits (296), Expect = 2e-26
Identities = 71/279 (25%), Positives = 136/279 (48%), Gaps = 10/279 (3%)
Query: 6 TPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLL 65
T + F LG G + V + T +A+KV K I+ ++V+ + +EK +
Sbjct: 686 TVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVS 745
Query: 66 AHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALE 125
+ HP ++ L F +E+++F ++++ F+E + ++ L+
Sbjct: 746 SRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDV-FDEVRGCFYAACVVLGLD 804
Query: 126 YIHGCKVVHRDLKPENLLLSSEGKLMITDFGVAS-NLAATDNLSSTSSFVGTAEYVSPEL 184
++H +++RD+K +NLLL EG + I DFG+ N+ D TS+F GT E+++PE+
Sbjct: 805 FLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDK---TSTFCGTPEFLAPEV 861
Query: 185 LLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLV 244
L + D W +G ++++ G PPF G++E F+ I++ D + +S ++
Sbjct: 862 LSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIM 921
Query: 245 SKILVLDPDSRY-----TLPQIKNHAWFQGIDWTNKELI 278
++L P+ R IK +F+ I W +L+
Sbjct: 922 RRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLL 960
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 118 bits (296), Expect = 2e-26
Identities = 75/260 (28%), Positives = 128/260 (48%), Gaps = 7/260 (2%)
Query: 10 FSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGN 69
+ KE LG G++ V + +T A+K+ +++ I S + V + E L+L
Sbjct: 25 YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLF---R 81
Query: 70 HPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHG 129
HP II+LY +++ +++ R A + F Q+I ++Y H
Sbjct: 82 HPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHR 141
Query: 130 CKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL-QN 188
VVHRDLKPENLLL + + I DFG+++ + D L ++ G+ Y +PE++ +
Sbjct: 142 HMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFLRTS---CGSPNYAAPEVISGKL 198
Query: 189 KSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKIL 248
+ D+W+ G +LY GT PF E+ + F KI + + + + I +L+ +L
Sbjct: 199 YAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHML 258
Query: 249 VLDPDSRYTLPQIKNHAWFQ 268
+DP R T+ + H WFQ
Sbjct: 259 CVDPMKRATIKDVIAHEWFQ 278
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 118 bits (296), Expect = 2e-26
Identities = 76/271 (28%), Positives = 131/271 (48%), Gaps = 15/271 (5%)
Query: 4 KRTPQDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLN 63
K ++ + LG G + T + + TGQ A K K+ ++ + V E ++
Sbjct: 16 KNVEDNYFLGQVLGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDYDDVLREIQIMH 75
Query: 64 LLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDA 123
L+ +P ++++ + D++N++ V++ ++E + ++
Sbjct: 76 HLSE--YPNVVRIESAYEDTKNVHLVMELCEGGELFDRIVKRGHYSEREAAKLIKTIVGV 133
Query: 124 LEYIHGCKVVHRDLKPENLLLSS---EGKLMITDFGVASNLAATDNLSSTSSFVGTAEYV 180
+E H VVHRDLKPEN L SS + L TDFG++ + + S VG+A YV
Sbjct: 134 VEACHSLGVVHRDLKPENFLFSSSDEDASLKSTDFGLSVFCTPGE---AFSELVGSAYYV 190
Query: 181 SPELLLQNKSNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIV--NLDYH---WIYM 235
+PE+L ++ C D+W+ G +LY G PPF E+E+ F KI+ L++ W
Sbjct: 191 APEVLHKHYGPEC-DVWSAGVILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPW-PS 248
Query: 236 VSQHITDLVSKILVLDPDSRYTLPQIKNHAW 266
+S+ DL+ K+L +P R T Q+ H W
Sbjct: 249 ISESAKDLIKKMLESNPKKRLTAHQVLCHPW 279
>Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1152
Score = 118 bits (295), Expect = 3e-26
Identities = 78/274 (28%), Positives = 137/274 (49%), Gaps = 18/274 (6%)
Query: 1 MSRKRTPQDF-SFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEK 59
+ R P+DF LG G++ VYKA ++ T L A KV K SE +++ +E
Sbjct: 24 VKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTK---SEEELEDYMVE- 79
Query: 60 NTLNLLAHGNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXR-FNEAWTKHFMC 118
+++LA +HP I+KL F+ NL+ +++F R E+ +
Sbjct: 80 --IDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCK 137
Query: 119 QLIDALEYIHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAE 178
Q +DAL Y+H K++HRDLK N+L + +G + + DFGV++ T + SF+GT
Sbjct: 138 QTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAK--NTRTIQRRDSFIGTPY 195
Query: 179 YVSPELLLQNKS-----NFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWI 233
+++PE+++ S ++ +D+W++G L + + PP N + KI + +
Sbjct: 196 WMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTL 255
Query: 234 YMVSQ---HITDLVSKILVLDPDSRYTLPQIKNH 264
S+ + D + K L + D+R+T Q+ H
Sbjct: 256 AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQH 289
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 118 bits (295), Expect = 3e-26
Identities = 65/252 (25%), Positives = 122/252 (47%), Gaps = 5/252 (1%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG G ++ Y+ D + +++A K+ + ++ + + E +L +H +++
Sbjct: 88 LGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRIL---HHKHVVQ 144
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
Y+ F D EN+Y +L++ E ++++ Q++ L+Y+H +++HR
Sbjct: 145 FYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHR 204
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLK N ++ +L + DFG+A+ L ++ T GT Y+SPE+L + SD
Sbjct: 205 DLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRT--ICGTPNYLSPEVLNKQGHGCESD 262
Query: 196 IWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPDSR 255
IWA+GC++Y G PPF N + I Y + L++ +L +P+ R
Sbjct: 263 IWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDR 322
Query: 256 YTLPQIKNHAWF 267
+L I H +F
Sbjct: 323 PSLDDIIRHDFF 334
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 118 bits (295), Expect = 3e-26
Identities = 73/276 (26%), Positives = 135/276 (48%), Gaps = 17/276 (6%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+D+ + +G G++ V +ST +++A+K+ SK +I + + E++ ++A
Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERD---IMAF 130
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYI 127
N P +++L+Y F D LY V+++ P E W + + +++ AL+ I
Sbjct: 131 ANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEKWARFYTAEVVLALDAI 189
Query: 128 HGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQ 187
H +HRD+KP+N+LL G L + DFG + + + + VGT +Y+SPE+L
Sbjct: 190 HSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKM-NKEGMVRCDTAVGTPDYISPEVLKS 248
Query: 188 NKSNFC----SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVN----LDYHWIYMVSQH 239
+ D W+VG LY+ G PF ++ + + KI+N L + +S+
Sbjct: 249 QGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKE 308
Query: 240 ITDLVSKILVLDPD---SRYTLPQIKNHAWFQGIDW 272
+L+ L D + R + +IK H +F+ W
Sbjct: 309 AKNLICAFLT-DREVRLGRNGVEEIKRHLFFKNDQW 343
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 118 bits (295), Expect = 3e-26
Identities = 73/280 (26%), Positives = 136/280 (48%), Gaps = 17/280 (6%)
Query: 8 QDFSFKERLGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAH 67
+DF + +G G++ V ++ ++FA+K+ +K ++ + E++ +L +
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERD---VLVN 131
Query: 68 GNHPGIIKLYYTFHDSENLYFVLDF-APXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEY 126
G++ I L+Y F D NLY V+D+ R E + ++ +++ A++
Sbjct: 132 GDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDS 191
Query: 127 IHGCKVVHRDLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLL 186
+H VHRD+KP+N+L+ G + + DFG L D +S VGT +Y+SPE+L
Sbjct: 192 VHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKL-MEDGTVQSSVAVGTPDYISPEILQ 250
Query: 187 ---QNKSNFC--SDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYHW-----IYMV 236
K + D W++G +Y+ G PF E+ + + KI+N + + V
Sbjct: 251 AMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDV 310
Query: 237 SQHITDLVSKILVLDPD--SRYTLPQIKNHAWFQGIDWTN 274
S++ DL+ +++ + + K H +F GIDW N
Sbjct: 311 SENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDN 350
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 118 bits (295), Expect = 3e-26
Identities = 74/242 (30%), Positives = 116/242 (47%), Gaps = 10/242 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIISENKVKYVTIEKNTLNLLAHGNHPGIIK 75
LG+GS+ TV ++S +A K+ SK+ ++ +V +V EK+ LN P +I
Sbjct: 51 LGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNA---ARFPFLIY 107
Query: 76 LYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKHFMCQLIDALEYIHGCKVVHR 135
L + + LY +L +FNE + + Q+ ALEY+H +++R
Sbjct: 108 LVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYR 167
Query: 136 DLKPENLLLSSEGKLMITDFGVASNLAATDNLSSTSSFVGTAEYVSPELLLQNKSNFCSD 195
DLKPEN+LL G + ITDFG + TS+ GT EY++PE++ N D
Sbjct: 168 DLKPENILLDQRGYIKITDFGFTKRVD-----GRTSTLCGTPEYLAPEIVQLRPYNKSVD 222
Query: 196 IWAVGCMLYQFTQGTPPFRGENE--LAAFEKIVNLDYHWIYMVSQHITDLVSKILVLDPD 253
WA G ++Y+F G PF N + + KI DY + + LV ++ +D
Sbjct: 223 WWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTS 282
Query: 254 SR 255
R
Sbjct: 283 KR 284
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 118 bits (295), Expect = 3e-26
Identities = 78/262 (29%), Positives = 130/262 (48%), Gaps = 12/262 (4%)
Query: 16 LGHGSYSTVYKAVDRSTGQLFAIKVCSKKHIIS-ENKVKYVTIEKNTLNLLAHGNHPGII 74
LG GSY V +A++ A+K+ +K+ + N + VT E L L H + ++
Sbjct: 151 LGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHRHVVELV 210
Query: 75 KLYYTFHDSENLYFVLDFAPXXXXXXXXXXXXRFNEAWTKH-FMCQLIDALEYIHGCKVV 133
+ Y + + +Y V+++ + + H + QL+D LEY+H C+V+
Sbjct: 211 DVLYN-EEKQKMYLVMEYCVGGLQEMIDYQPDKRMPLFQAHGYFKQLVDGLEYLHSCRVI 269
Query: 134 HRDLKPENLLLSSEGKLMITDFGVAS--NLAATDNLSSTSSFVGTAEYVSPELLLQNK-- 189
H+D+KP NLLLS + L I+DFGVA +L A D+ +T G+ + PE+ ++
Sbjct: 270 HKDIKPGNLLLSLDQTLKISDFGVAEQLDLFAPDDTCTTGQ--GSPAFQPPEIANGHETF 327
Query: 190 SNFCSDIWAVGCMLYQFTQGTPPFRGENELAAFEKIVNLDYH---WIYMVSQHITDLVSK 246
+ F DIW+ G LY G PF G+N E I + W+Y + +L+
Sbjct: 328 AGFKVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFANLILG 387
Query: 247 ILVLDPDSRYTLPQIKNHAWFQ 268
+L DP R +L +I++ WF+
Sbjct: 388 MLQADPSKRLSLQEIRHDTWFR 409
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,216,136
Number of Sequences: 60738
Number of extensions: 1780057
Number of successful extensions: 11214
Number of sequences better than 1.0e-05: 1637
Number of HSP's better than 0.0 without gapping: 532
Number of HSP's successfully gapped in prelim test: 1105
Number of HSP's that attempted gapping in prelim test: 7101
Number of HSP's gapped (non-prelim): 2203
length of query: 647
length of database: 30,389,216
effective HSP length: 113
effective length of query: 534
effective length of database: 23,525,822
effective search space: 12562788948
effective search space used: 12562788948
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)