ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1096 good T KOG1113 Signal transduction mechanisms cAMP-dependent protein kinase types I and II, regulatory subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1096 378888 380285 466
(466 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL033c [T] KOG1113 cAMP-dependent protein kinase types I and II... 504 e-143
SPAC8C9.03 [T] KOG1113 cAMP-dependent protein kinase types I and... 231 2e-60
7303815 [T] KOG1113 cAMP-dependent protein kinase types I and II... 212 1e-54
CE28749 [T] KOG1113 cAMP-dependent protein kinase types I and II... 209 5e-54
CE04821 [T] KOG1113 cAMP-dependent protein kinase types I and II... 209 5e-54
7296360 [T] KOG1113 cAMP-dependent protein kinase types I and II... 201 3e-51
Hs4506063 [T] KOG1113 cAMP-dependent protein kinase types I and ... 199 6e-51
Hs4758958 [T] KOG1113 cAMP-dependent protein kinase types I and ... 197 4e-50
Hs4506065 [T] KOG1113 cAMP-dependent protein kinase types I and ... 197 4e-50
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 142 1e-33
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 131 2e-30
7296166 [T] KOG0614 cGMP-dependent protein kinase 130 3e-30
7297611 [T] KOG0614 cGMP-dependent protein kinase 125 1e-28
CE19898 [T] KOG0614 cGMP-dependent protein kinase 117 3e-26
CE19897 [T] KOG0614 cGMP-dependent protein kinase 117 3e-26
CE03979 [T] KOG0614 cGMP-dependent protein kinase 76 9e-14
ECU08g0930 [T] KOG1113 cAMP-dependent protein kinase types I and... 73 8e-13
Hs5901914 [T] KOG2378 cAMP-regulated guanine nucleotide exchange... 61 4e-09
Hs20070215 [T] KOG2378 cAMP-regulated guanine nucleotide exchang... 59 2e-08
CE23992 [T] KOG2378 cAMP-regulated guanine nucleotide exchange f... 58 3e-08
7302302 [T] KOG2378 cAMP-regulated guanine nucleotide exchange f... 58 3e-08
7303201 [PT] KOG0498 K+-channel ERG and related proteins contain... 55 2e-07
>YIL033c [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 416
Score = 504 bits (1299), Expect = e-143
Identities = 264/459 (57%), Positives = 317/459 (68%), Gaps = 53/459 (11%)
Query: 5 QTELDLFKNEVEQKQPNDFLQFAANYFTKRLEQQRTFVRNQESLALSKGIVLFPSTSKHD 64
Q EL LF+NE+ P+DFLQF+ANYF KRLEQQR F++ +E +K IVLFP +
Sbjct: 10 QAELQLFQNEINAANPSDFLQFSANYFNKRLEQQRAFLKAREPEFKAKNIVLFPEPEE-- 67
Query: 65 XXXXXXXXXXXXXXXXNASQSGISSSGVDEDVLFKSPFVDRGPHSTHIVDHLDSTHSNTT 124
+ QS S S V+FKSPFV+ PHS
Sbjct: 68 --------------SFSRPQSAQSQSRSRSSVMFKSPFVNEDPHSN-------------- 99
Query: 125 ASPAKASGGDAPGIFKGNFNVGTESQRKVNSSVDPMAPEPTATTHSFPRRSVVNPKPLPI 184
+FK FN+ Q A E T R + PLP+
Sbjct: 100 -------------VFKSGFNLDPHEQ-----DTHQQAQEEQQHT-----REKTSTPPLPM 136
Query: 185 NFNAQRRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLV 244
+FNAQRRTSVSGETLQP++ DDW P++++EKS +Q+ RLEK++ NFLFNKLDSDSK+LV
Sbjct: 137 HFNAQRRTSVSGETLQPNNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLV 196
Query: 245 INSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNS 304
IN LEEKS+P+G IIKQGD+GDYFY+VE GTV+FYVN+ KVN+SGPGSSFGELALMYNS
Sbjct: 197 INCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNS 256
Query: 305 PRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLAD 364
PRAATV+A++DC+LWALDRLTFR+ILLG SFKKR++YDDLLK++P+LKSL+TYDRAKLAD
Sbjct: 257 PRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLAD 316
Query: 365 ALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQEGKGVITKLGKGDYFGEVALLNDLP 424
ALDT+ Y+ G+TII+EGD GENFY IEYG DVS++G+GVI KL DYFGEVALLNDLP
Sbjct: 317 ALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLP 376
Query: 425 RQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLKLNDPTR 463
RQ LGKSGFQRLLGP VDVLKLNDPTR
Sbjct: 377 RQATVTATKRTKVATLGKSGFQRLLGPAVDVLKLNDPTR 415
>SPAC8C9.03 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 412
Score = 231 bits (589), Expect = 2e-60
Identities = 127/296 (42%), Positives = 179/296 (59%), Gaps = 18/296 (6%)
Query: 183 PINFNAQRRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKK 242
P N+N RR SVS E++ P F K PE + RL+++V NFLF LD +
Sbjct: 94 PQNYNLLRRQSVSTESMNPSAFALETKRTFPPKDPEDLKRLKRSVAGNFLFKNLDEEHYN 153
Query: 243 LVINSLEEKSIPQ-GKEIIKQGDEGDYFYIVEDGTVEFY------VNNQKVNTSG----- 290
V+N++ EK I + G +I QG GDYFYIVE G + Y + ++V +SG
Sbjct: 154 EVLNAMTEKRIGEAGVAVIVQGAVGDYFYIVEQGEFDVYKRPELNITPEEVLSSGYGNYI 213
Query: 291 ----PGSSFGELALMYNSPRAATVIAST-DCILWALDRLTFRRILLGGSFKKRILYDDLL 345
PG FGELALMYN+PRAA+V++ T + +++ALDR +FRRI+ ++++R+LY+ LL
Sbjct: 214 TTISPGEYFGELALMYNAPRAASVVSKTPNNVIYALDRTSFRRIVFENAYRQRMLYESLL 273
Query: 346 KNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQEGKGVI 405
+ +PIL SL Y R K+ADAL T Y+AG +I++GD G FY IE GEA+V + GKGV+
Sbjct: 274 EEVPILSSLDKYQRQKIADALQTVVYQAGSIVIRQGDIGNQFYLIEDGEAEVVKNGKGVV 333
Query: 406 TKLGKGDYFGEVALLNDLPRQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLKLNDP 461
L KGDYFGE+AL+++ R K F RLLG +D+++ N P
Sbjct: 334 VTLTKGDYFGELALIHETVRNATVQAKTRLKLATFDKPTFNRLLGNAIDLMR-NQP 388
>7303815 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 411
Score = 212 bits (539), Expect = 1e-54
Identities = 117/278 (42%), Positives = 168/278 (60%), Gaps = 7/278 (2%)
Query: 188 AQRRTSVSGETLQP--DHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVI 245
+ RR SV E P D DD F K+ EQ +RL ++V LF L+ + V+
Sbjct: 79 SSRRKSVFAEAYDPEADDDDDGATAVFP-KTDEQRARLVESVKNVLLFRSLEKEQMNQVL 137
Query: 246 NSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSP 305
+++ E+ + G II+QGD+GD FY++E G + Y+N++ +NT FGELAL+YN P
Sbjct: 138 DAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHINTYNHTGLFGELALLYNMP 197
Query: 306 RAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADA 365
RAATV A T +LWA+DR TFRRILL +F+KR +Y++LL ++P+LK+L Y+R LADA
Sbjct: 198 RAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADA 257
Query: 366 LDTEYYEAGQTIIKEGDTGENFYFIEYGEADV---SQEGKGVITKLGKGDYFGEVALLND 422
L ++ Y+ G+ IIK+GD + YFIE G V + + I++LGKG YFGE+AL+
Sbjct: 258 LVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTH 317
Query: 423 LPRQXX-XXXXXXXXXXXLGKSGFQRLLGPVVDVLKLN 459
PR L F+R++G + DVLK N
Sbjct: 318 RPRAASVYATGGVVKLAFLDTEAFERIMGFLTDVLKRN 355
>CE28749 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 334
Score = 209 bits (533), Expect = 5e-54
Identities = 114/273 (41%), Positives = 168/273 (60%), Gaps = 7/273 (2%)
Query: 190 RRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSLE 249
RRT +S E ++ D + K ++ + + LE A+ KN LF L+ D +K + +++
Sbjct: 50 RRTGISAEPIKEDDTEYKKVVIPKDDATRR--SLESAMRKNLLFAHLEEDEQKTMYDAMF 107
Query: 250 EKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAAT 309
G+ II+QG+EGD FY+++ GTV+ YVN++ V T G SFGELAL+Y +PRAAT
Sbjct: 108 PVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAAT 167
Query: 310 VIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDTE 369
VIA TD LWA+DRLT+RRIL+G KKR +YD+ L + IL L ++RA +ADAL+
Sbjct: 168 VIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERC 227
Query: 370 YYEAGQTIIKEGDTGENFYFIEYGEADVSQEGK-----GVITKLGKGDYFGEVALLNDLP 424
+E G ++++G G+ F+ I GEA+V Q+ V+ LG DYFGE+ALL D P
Sbjct: 228 DFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRP 287
Query: 425 RQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLK 457
R L ++ F+R++GPV ++LK
Sbjct: 288 RAATVVAKTHLKCIKLDRNRFERVMGPVREILK 320
>CE04821 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 376
Score = 209 bits (533), Expect = 5e-54
Identities = 114/273 (41%), Positives = 168/273 (60%), Gaps = 7/273 (2%)
Query: 190 RRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSLE 249
RRT +S E ++ D + K ++ + + LE A+ KN LF L+ D +K + +++
Sbjct: 92 RRTGISAEPIKEDDTEYKKVVIPKDDATRR--SLESAMRKNLLFAHLEEDEQKTMYDAMF 149
Query: 250 EKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAAT 309
G+ II+QG+EGD FY+++ GTV+ YVN++ V T G SFGELAL+Y +PRAAT
Sbjct: 150 PVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAAT 209
Query: 310 VIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDTE 369
VIA TD LWA+DRLT+RRIL+G KKR +YD+ L + IL L ++RA +ADAL+
Sbjct: 210 VIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERC 269
Query: 370 YYEAGQTIIKEGDTGENFYFIEYGEADVSQEGK-----GVITKLGKGDYFGEVALLNDLP 424
+E G ++++G G+ F+ I GEA+V Q+ V+ LG DYFGE+ALL D P
Sbjct: 270 DFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRP 329
Query: 425 RQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLK 457
R L ++ F+R++GPV ++LK
Sbjct: 330 RAATVVAKTHLKCIKLDRNRFERVMGPVREILK 362
>7296360 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 299
Score = 201 bits (510), Expect = 3e-51
Identities = 108/277 (38%), Positives = 167/277 (59%), Gaps = 7/277 (2%)
Query: 189 QRRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSL 248
+RR +S E + + ++ + K + ++ L KA+ KN LF LD + + +++
Sbjct: 10 RRRGGISAEPVTEEDATNYV-KKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAM 68
Query: 249 EEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAA 308
+ G+ II+QGDEGD FY+++ G V+ +VN++ V T G SFGELAL+Y +PRAA
Sbjct: 69 FPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAA 128
Query: 309 TVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDT 368
TV A TD LW +DR ++RRIL+G + +KR +Y++ L + IL+SL ++R +AD+L+T
Sbjct: 129 TVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLET 188
Query: 369 EYYEAGQTIIKEGDTGENFYFIEYGEADVSQ------EGKGVITKLGKGDYFGEVALLND 422
++ G+TI+K+G G++FY I G A V Q E + +LG DYFGE+ALL D
Sbjct: 189 CSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEQGEDPAEVGRLGSSDYFGEIALLLD 248
Query: 423 LPRQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLKLN 459
PR L ++ F+R+LGP D+LK N
Sbjct: 249 RPRAATVVARGPLKCVKLDRARFERVLGPCADILKRN 285
>Hs4506063 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 381
Score = 199 bits (507), Expect = 6e-51
Identities = 108/286 (37%), Positives = 167/286 (57%), Gaps = 6/286 (2%)
Query: 179 PKPLPINFNAQRRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDS 238
P P P+ +RR ++S E + + + K + ++ L KA+ KN LF+ LD
Sbjct: 85 PPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIP-KDYKTMAALAKAIEKNVLFSHLDD 143
Query: 239 DSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGEL 298
+ + + +++ S G+ +I+QGDEGD FY+++ G + YVNN+ + G G SFGEL
Sbjct: 144 NERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGEL 203
Query: 299 ALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYD 358
AL+Y +PRAATV A T+ LW +DR ++RRIL+G + +KR +Y++ L + IL+SL ++
Sbjct: 204 ALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWE 263
Query: 359 RAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQ-----EGKGVITKLGKGDY 413
R +ADAL+ +E GQ I+ +G+ G+ F+ I G A V Q E + +LG DY
Sbjct: 264 RLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDY 323
Query: 414 FGEVALLNDLPRQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLKLN 459
FGE+ALL + PR L + F+R+LGP D+LK N
Sbjct: 324 FGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRN 369
>Hs4758958 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 404
Score = 197 bits (500), Expect = 4e-50
Identities = 108/295 (36%), Positives = 169/295 (56%), Gaps = 18/295 (6%)
Query: 181 PLPINFNAQRRTSVSGETLQPDHLD-DWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSD 239
P+P FN RR SV ET PD + D P K+ EQ RL++A LF LD +
Sbjct: 89 PVPSRFN--RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQE 146
Query: 240 SKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNN----QKVNTSGPGSSF 295
V++++ E+ + + +I QGD+GD FY++E GT + V + V SF
Sbjct: 147 QLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSF 206
Query: 296 GELALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLS 355
GELALMYN+PRAAT++A+++ LW LDR+TFRRI++ + KKR +++ ++++P+LKSL
Sbjct: 207 GELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLE 266
Query: 356 TYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADV--------SQEG---KGV 404
+R K+ D + + Y+ G+ II +G+ ++FY IE GE + +++G +
Sbjct: 267 VSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVE 326
Query: 405 ITKLGKGDYFGEVALLNDLPRQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLKLN 459
I + KG YFGE+AL+ + PR + F+RLLGP +D++K N
Sbjct: 327 IARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRN 381
>Hs4506065 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 418
Score = 197 bits (500), Expect = 4e-50
Identities = 105/295 (35%), Positives = 166/295 (55%), Gaps = 15/295 (5%)
Query: 183 PINFNAQRRTSVSGETLQPDHL-DDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSK 241
P+ RR SV E PD DD + K+ +Q +RL++A LF LD +
Sbjct: 104 PVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQM 163
Query: 242 KLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVN----NQKVNTSGPGSSFGE 297
V++++ EK + G+ +I QGD+GD FY+++ GT + YV + V SFGE
Sbjct: 164 SQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGE 223
Query: 298 LALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTY 357
LALMYN+PRAAT+ A++ LW LDR+TFRRI++ + KKR +Y+ ++++P LKSL
Sbjct: 224 LALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFS 283
Query: 358 DRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQEGKG----------VITK 407
+R K+ D + T+ Y G+ II +GD+ ++F+ +E GE ++ + KG + +
Sbjct: 284 ERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEMPR 343
Query: 408 LGKGDYFGEVALLNDLPRQXXXXXXXXXXXXXLGKSGFQRLLGPVVDVLKLNDPT 462
+G YFGE+AL+ + PR + F+RLLGP ++++K N T
Sbjct: 344 CSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIAT 398
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 142 bits (358), Expect = 1e-33
Identities = 82/249 (32%), Positives = 128/249 (50%), Gaps = 5/249 (2%)
Query: 212 FQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYI 271
F KSP+ +++A+ N L+ + +++ + + IIK+GD G Y+
Sbjct: 98 FYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYV 157
Query: 272 VEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAATVIASTDCILWALDRLTFRRILL 331
+EDG VE K+ T GPG FGELA++YN R ATV + LWA+DR F+ I++
Sbjct: 158 MEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMM 217
Query: 332 GGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIE 391
K Y + LK++P +SL +KLAD L+ +YE G+ II++G G+ F+ I
Sbjct: 218 RTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIIS 277
Query: 392 YGEADVSQEGKG-----VITKLGKGDYFGEVALLNDLPRQXXXXXXXXXXXXXLGKSGFQ 446
G +V++E + LGKGD+FGE AL + R + + F+
Sbjct: 278 KGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFK 337
Query: 447 RLLGPVVDV 455
L+G + DV
Sbjct: 338 HLIGGLDDV 346
Score = 53.5 bits (127), Expect = 6e-07
Identities = 39/138 (28%), Positives = 58/138 (41%), Gaps = 6/138 (4%)
Query: 233 FNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQK------V 286
F L + + + LEE G+ II+QG GD F+I+ GTV + +
Sbjct: 237 FQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFL 296
Query: 287 NTSGPGSSFGELALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLK 346
T G G FGE AL R A VIA+ +DR +F+ ++ G Y+D
Sbjct: 297 RTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEA 356
Query: 347 NIPILKSLSTYDRAKLAD 364
+ + KL+D
Sbjct: 357 KAKYEAEAAFFANLKLSD 374
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 131 bits (329), Expect = 2e-30
Identities = 77/246 (31%), Positives = 133/246 (53%), Gaps = 13/246 (5%)
Query: 190 RRTSVSGETLQPDH--LDDWKPENFQ------EKSPEQVSRLEKAVGKNFLFNKLDSDSK 241
RR + +G + +P D KP F K + + A+ KN +LD
Sbjct: 118 RRGAKAGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQI 177
Query: 242 KLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALM 301
K ++ + ++ QG IIKQG+ G++ +++ +G +E + + +++ ++FGELA++
Sbjct: 178 KDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAIL 237
Query: 302 YNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAK 361
YN R A+V A T+ WALDR F+ I+ + + Y + L+++ +LK+L K
Sbjct: 238 YNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTK 297
Query: 362 LADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQEGKG-----VITKLGKGDYFGE 416
+ D L+ EYY+ G II+EG+ G F+ + G+ V+Q +G +I L KG+YFGE
Sbjct: 298 IIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGE 357
Query: 417 VALLND 422
AL++D
Sbjct: 358 KALISD 363
Score = 51.2 bits (121), Expect = 3e-06
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 17/168 (10%)
Query: 182 LPINFNAQRRTSVSGET-LQPDHLDDWKPENFQEKSP----EQVSRLEKAVGKNFLFNKL 236
L I +N R SV T ++ LD +N ++ EQ ++V L L
Sbjct: 234 LAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVS---LLKNL 290
Query: 237 DSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTV------EFYVNNQKVNTSG 290
D +I+ LE + +G II++G+EG F+I+ G V E + Q + T
Sbjct: 291 PEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQ 350
Query: 291 PGSSFGELALMYNSPRAATVIA-STDCILWALDRLTFRRILLGGSFKK 337
G FGE AL+ + R+A +IA D +DR TF + + G+F++
Sbjct: 351 KGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTV--GTFEE 396
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 130 bits (328), Expect = 3e-30
Identities = 84/308 (27%), Positives = 154/308 (49%), Gaps = 12/308 (3%)
Query: 157 VDPMAPEPTATTHSFPRRSVVNPKPLPINFNAQRRTSVSGETLQPDHLDDWK-PENFQEK 215
+ P+A +A+ V PK +P A ++ VS E+ + P EK
Sbjct: 112 LSPLASTSSASPSGRTSADEVRPKAMPA---AIKKQGVSAESCVQSMQQSYSIPIPKYEK 168
Query: 216 SPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDG 275
+++ A+ N +D+ + +++S+ KSI G+ +I++G+ G + Y+ G
Sbjct: 169 DFSDKQQIKDAIMDNDFLKNIDASQVRELVDSMYSKSIAAGEFVIREGEVGAHLYVSAAG 228
Query: 276 TVEFYVNNQKVNTSGPGSSFGELALMYNSPRAATV-IASTDCILWALDRLTFRRILLGGS 334
+ ++ G G +FGELA++YN R A++ + S +W LDR F++I++
Sbjct: 229 EFAVMQQGKVLDKMGAGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVFQQIMMCTG 288
Query: 335 FKKRILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGE 394
++ + L+++P+L +LS AK+AD L+ E+Y AG II++G G++F+ I G
Sbjct: 289 LQRIENSVNFLRSVPLLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGN 348
Query: 395 ADVSQE------GKGVITKLGKGDYFGEVALLNDLPRQXXXXXXX-XXXXXXLGKSGFQR 447
V+Q+ + + L +GDYFGE AL+N+ R L + F+R
Sbjct: 349 VRVTQKLTPTSPEETELRTLSRGDYFGEQALINEDKRTANIIALSPGVECLTLDRDSFKR 408
Query: 448 LLGPVVDV 455
L+G + ++
Sbjct: 409 LIGDLCEL 416
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 125 bits (314), Expect = 1e-28
Identities = 70/209 (33%), Positives = 114/209 (54%), Gaps = 5/209 (2%)
Query: 223 LEKAVGKN-FLFNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYV 281
+ A+ +N FL N +D + K++VIN++ S + II++ +EG Y+ +G +
Sbjct: 422 IRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIR 481
Query: 282 NNQKVNTSGPGSSFGELALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILY 341
Q V + GP + FGELA++YN+PR A++ A+TD +W + R TFR I+ ++R
Sbjct: 482 GGQLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREEN 541
Query: 342 DDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADV---- 397
L++ P L+ K+ D L ++YE I++EG+ G FY I G +
Sbjct: 542 LQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVTIKKLD 601
Query: 398 SQEGKGVITKLGKGDYFGEVALLNDLPRQ 426
Q+ + ++ +GDYFGE ALLN RQ
Sbjct: 602 EQQQEQIVANRKRGDYFGEQALLNADVRQ 630
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 117 bits (294), Expect = 3e-26
Identities = 77/266 (28%), Positives = 129/266 (47%), Gaps = 17/266 (6%)
Query: 208 KPENFQEKSPEQVSRLEKAVG----------KNFLFNKLDSDSKKLVINSLEEKSIPQGK 257
+P NF+ K P + K VG KN +L + ++N + E G+
Sbjct: 125 EPTNFENK-PATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQ 183
Query: 258 EIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAATVIASTDCI 317
+I++G+ GD ++V +G ++ + G+ GELA++YN R A+V A TD
Sbjct: 184 WVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQ 243
Query: 318 LWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTI 377
LW LDR F+ I ++ + L + I ++LS +K+AD +D +YY+ G I
Sbjct: 244 LWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYI 303
Query: 378 IKEGDTGENFYFIEYGEADVSQEGKG-----VITKLGKGDYFGEVALLNDLPRQXXXXXX 432
I++G+ G+ F+ I G+ V+Q+ +G I L +GD+FGE ALL + R
Sbjct: 304 IRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQ 363
Query: 433 X-XXXXXXLGKSGFQRLLGPVVDVLK 457
L + F +L+G + + K
Sbjct: 364 APGVEVLTLDRESFGKLIGDLESLKK 389
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 117 bits (294), Expect = 3e-26
Identities = 77/266 (28%), Positives = 129/266 (47%), Gaps = 17/266 (6%)
Query: 208 KPENFQEKSPEQVSRLEKAVG----------KNFLFNKLDSDSKKLVINSLEEKSIPQGK 257
+P NF+ K P + K VG KN +L + ++N + E G+
Sbjct: 168 EPTNFENK-PATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQ 226
Query: 258 EIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAATVIASTDCI 317
+I++G+ GD ++V +G ++ + G+ GELA++YN R A+V A TD
Sbjct: 227 WVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQ 286
Query: 318 LWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTI 377
LW LDR F+ I ++ + L + I ++LS +K+AD +D +YY+ G I
Sbjct: 287 LWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYI 346
Query: 378 IKEGDTGENFYFIEYGEADVSQEGKG-----VITKLGKGDYFGEVALLNDLPRQXXXXXX 432
I++G+ G+ F+ I G+ V+Q+ +G I L +GD+FGE ALL + R
Sbjct: 347 IRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQ 406
Query: 433 X-XXXXXXLGKSGFQRLLGPVVDVLK 457
L + F +L+G + + K
Sbjct: 407 APGVEVLTLDRESFGKLIGDLESLKK 432
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 76.3 bits (186), Expect = 9e-14
Identities = 39/121 (32%), Positives = 68/121 (55%)
Query: 226 AVGKNFLFNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQK 285
A+ N LD+ + + +++ +P G II+QGD G Y++++G V+ +N+
Sbjct: 30 ALRLNSFLRNLDATQIEKISSAMYPVEVPAGAIIIRQGDLGSIMYVIQEGKVQVVKDNRF 89
Query: 286 VNTSGPGSSFGELALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLL 345
V T G+ FGELA++++ R ATV A C LWA++R F I++ + +K + + L
Sbjct: 90 VRTMEDGALFGELAILHHCERTATVRAIESCHLWAIERNVFHAIMMESAREKTMSFKRHL 149
Query: 346 K 346
K
Sbjct: 150 K 150
>ECU08g0930 [T] KOG1113 cAMP-dependent protein kinase types I and II regulatory
subunit
Length = 312
Score = 73.2 bits (178), Expect = 8e-13
Identities = 55/224 (24%), Positives = 102/224 (44%), Gaps = 6/224 (2%)
Query: 186 FNAQRRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVI 245
+ A RR+ V E + P+ N+ K E + L + + F L+ + K +I
Sbjct: 76 WRASRRSGVYSERITPETFR----LNYYPKDEETIRFLSSILVSDIPFGFLNPEQKTRLI 131
Query: 246 NSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSP 305
S E I +G ++ +G+ G YIV G E + G FGE+AL++N P
Sbjct: 132 ESTELIEIKRGTFVMHEGEIGSQMYIVASGEFEVTKGGTLLRKLTKGCFFGEIALLHNIP 191
Query: 306 RAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADA 365
R ATV A TD +W +++ +F I + + + + L+ + D ++ ++
Sbjct: 192 RTATVKAVTDGKVWVVEQTSFSGIRMVDRILNKKIVLEGLREHRVFPLFRDEDYERVLNS 251
Query: 366 LDTEYYEAGQTI-IKEGDTGENFYFIEYGEADVSQ-EGKGVITK 407
L YY+ G + +K + + + E + +V + + K +I+K
Sbjct: 252 LSFVYYKKGSRVEVKSSEFLMSLFDGEVDDGEVRKIKAKEIISK 295
Score = 50.1 bits (118), Expect = 7e-06
Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 2/88 (2%)
Query: 338 RILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADV 397
R L L+ +IP L+ + +L ++ + + G ++ EG+ G Y + GE +V
Sbjct: 107 RFLSSILVSDIPF-GFLNPEQKTRLIESTELIEIKRGTFVMHEGEIGSQMYIVASGEFEV 165
Query: 398 SQEGKGVITKLGKGDYFGEVALLNDLPR 425
++ G ++ KL KG +FGE+ALL+++PR
Sbjct: 166 TKGGT-LLRKLTKGCFFGEIALLHNIPR 192
>Hs5901914 [T] KOG2378 cAMP-regulated guanine nucleotide exchange factor
Length = 1011
Score = 60.8 bits (146), Expect = 4e-09
Identities = 36/88 (40%), Positives = 55/88 (61%), Gaps = 2/88 (2%)
Query: 339 ILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTII-KEGDTGENFYFIEYGEADV 397
I+Y++LL +I L LST + +LA L E + G T++ +G+ G ++Y I G +V
Sbjct: 346 IIYEELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNV 404
Query: 398 SQEGKGVITKLGKGDYFGEVALLNDLPR 425
GKGV+ L +GD FG++AL+ND PR
Sbjct: 405 VIYGKGVVCTLHEGDDFGKLALVNDAPR 432
>Hs20070215 [T] KOG2378 cAMP-regulated guanine nucleotide exchange factor
Length = 881
Score = 58.9 bits (141), Expect = 2e-08
Identities = 33/88 (37%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Query: 339 ILYDDLLKNIPILKSLSTYDRAKLADALDTE-YYEAGQTIIKEGDTGENFYFIEYGEADV 397
+++++LL +I + LS + +LA L E + +AG + +GD G ++Y I G +V
Sbjct: 193 LIFEELL-HIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV 251
Query: 398 SQEGKGVITKLGKGDYFGEVALLNDLPR 425
GKG++T L +GD FG++AL+ND PR
Sbjct: 252 VTHGKGLVTTLHEGDDFGQLALVNDAPR 279
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/96 (34%), Positives = 51/96 (52%), Gaps = 2/96 (2%)
Query: 237 DSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQK-VNTSGPGSSF 295
+S ++L L E G + QGD+G +YI+ G+V + + V T G F
Sbjct: 209 NSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDF 268
Query: 296 GELALMYNSPRAATVIASTD-CILWALDRLTFRRIL 330
G+LAL+ ++PRAAT+I D C +D+ F RI+
Sbjct: 269 GQLALVNDAPRAATIILREDNCHFLRVDKQDFNRII 304
>CE23992 [T] KOG2378 cAMP-regulated guanine nucleotide exchange factor
Length = 1234
Score = 58.2 bits (139), Expect = 3e-08
Identities = 38/119 (31%), Positives = 66/119 (54%), Gaps = 2/119 (1%)
Query: 214 EKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSLE-EKSIPQGKEIIKQGDEGDYFYIV 272
E+SPE++ + + + + L + K+ + N ++ E+ + G + +QG+ G Y+YIV
Sbjct: 553 ERSPEELEVVYEELTFIKALSHLSTMVKRQLSNFVKVEQYVHAGSVVFRQGEIGVYWYIV 612
Query: 273 EDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAATVIA-STDCILWALDRLTFRRIL 330
G VE VN + V G FG+LAL+ + PRAAT++ D + +D+ F +IL
Sbjct: 613 LKGAVEVNVNGKIVCLLREGDDFGKLALVNDLPRAATIVTYEDDSMFLVVDKHHFNQIL 671
Score = 54.3 bits (129), Expect = 4e-07
Identities = 31/88 (35%), Positives = 54/88 (61%), Gaps = 3/88 (3%)
Query: 339 ILYDDLLKNIPILKSLSTYDRAKLADALDTEYY-EAGQTIIKEGDTGENFYFIEYGEADV 397
++Y++L I L LST + +L++ + E Y AG + ++G+ G +Y + G +V
Sbjct: 561 VVYEELTF-IKALSHLSTMVKRQLSNFVKVEQYVHAGSVVFRQGEIGVYWYIVLKGAVEV 619
Query: 398 SQEGKGVITKLGKGDYFGEVALLNDLPR 425
+ GK ++ L +GD FG++AL+NDLPR
Sbjct: 620 NVNGK-IVCLLREGDDFGKLALVNDLPR 646
>7302302 [T] KOG2378 cAMP-regulated guanine nucleotide exchange factor
Length = 957
Score = 58.2 bits (139), Expect = 3e-08
Identities = 43/134 (32%), Positives = 70/134 (52%), Gaps = 14/134 (10%)
Query: 305 PRAATVIASTDCILWALDRL-------TFRRILLGGSFKK-----RILYDDLLKNIPILK 352
P+A + A+ + I AL L T R IL S ++ +++++L+ +I L
Sbjct: 261 PQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELV-HIAALS 319
Query: 353 SLSTYDRAKLADALDTEYY-EAGQTIIKEGDTGENFYFIEYGEADVSQEGKGVITKLGKG 411
LST + +L+ E + +AG + +GD G ++Y + G DV GKG + L G
Sbjct: 320 HLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTG 379
Query: 412 DYFGEVALLNDLPR 425
D FG++AL+ND PR
Sbjct: 380 DDFGKLALINDAPR 393
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/77 (40%), Positives = 47/77 (60%), Gaps = 2/77 (2%)
Query: 256 GKEIIKQGDEGDYFYIVEDGTVEFYVNNQ-KVNTSGPGSSFGELALMYNSPRAAT-VIAS 313
G + QGDEG +YI+ G+V+ ++ + V T G FG+LAL+ ++PRAAT V+
Sbjct: 342 GTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKE 401
Query: 314 TDCILWALDRLTFRRIL 330
+C L +D+ F RIL
Sbjct: 402 NNCHLLRVDKEHFNRIL 418
>7303201 [PT] KOG0498 K+-channel ERG and related proteins contain PAS/PAC
sensor domain
Length = 1307
Score = 55.5 bits (132), Expect = 2e-07
Identities = 35/99 (35%), Positives = 53/99 (53%), Gaps = 1/99 (1%)
Query: 233 FNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTS-GP 291
F DS+ V+ L+ + G IIK+G G Y +++G V+ + N +V TS
Sbjct: 1105 FANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSD 1164
Query: 292 GSSFGELALMYNSPRAATVIASTDCILWALDRLTFRRIL 330
GS FGE+ L+ N+ R A+V A T C L++L F +L
Sbjct: 1165 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVL 1203
Score = 52.8 bits (125), Expect = 1e-06
Identities = 27/82 (32%), Positives = 40/82 (47%)
Query: 344 LLKNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQEGKG 403
L+ ++P + + + + L E ++ G IIKEG G YFI+ G D+
Sbjct: 1098 LVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGE 1157
Query: 404 VITKLGKGDYFGEVALLNDLPR 425
V T L G YFGE+ LL + R
Sbjct: 1158 VATSLSDGSYFGEICLLTNARR 1179
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.134 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,594,779
Number of Sequences: 60738
Number of extensions: 1215732
Number of successful extensions: 2705
Number of sequences better than 1.0e-05: 22
Number of HSP's better than 0.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2587
Number of HSP's gapped (non-prelim): 39
length of query: 466
length of database: 30,389,216
effective HSP length: 110
effective length of query: 356
effective length of database: 23,708,036
effective search space: 8440060816
effective search space used: 8440060816
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)