ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1157 good B KOG3844 Chromatin structure and dynamics Predicted component of NuA3 histone acetyltransferase complex
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1157 404611 406410 600
(600 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER049w [B] KOG3844 Predicted component of NuA3 histone acetyltr... 703 0.0
SPBC6B1.08c [B] KOG3844 Predicted component of NuA3 histone acet... 381 e-105
CE01785 [B] KOG3844 Predicted component of NuA3 histone acetyltr... 79 3e-14
Hs8922694 [B] KOG3844 Predicted component of NuA3 histone acetyl... 65 2e-10
>YER049w [B] KOG3844 Predicted component of NuA3 histone acetyltransferase
complex
Length = 644
Score = 703 bits (1814), Expect = 0.0
Identities = 353/614 (57%), Positives = 440/614 (71%), Gaps = 39/614 (6%)
Query: 24 LESSKAVGSFNSKIWDKSFQDDLRQEIKNAQPYNWGTIRDLVDPNLLQEVRREIETSIHF 83
LE K G FN KIWDK+FQD L++EI+++QPYNWGTI +LV+ +LL+ VR+EIET IHF
Sbjct: 21 LEEDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWGTIHELVNDDLLRAVRKEIETEIHF 80
Query: 84 TQKETDIYKVNQSGDLANLSGLDDADLSKLPSLVKLRELLYSEKYRDFIAYVTQSGKLSG 143
T+KETDIY+VNQSGDLANLSGLD DLS+LP+L KLR++LYS++YRDF YVT++GKLSG
Sbjct: 81 TKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSG 140
Query: 144 SKTDISINTYTKGCHLLTHDDVIGSRRVSFILYLPEPERVWKEHYGGGLRLFPSIVPNVP 203
SKTD+SINTYTKGCHLLTHDDVIGSRR+SFILYLP+P+R WK HYGGGLRLFPSI+PNVP
Sbjct: 141 SKTDMSINTYTKGCHLLTHDDVIGSRRISFILYLPDPDRKWKSHYGGGLRLFPSILPNVP 200
Query: 204 FSDHSAKLVPQFNQIAFFKVQPGFSFHDVEEVKVDKHRLSIQGWYHIXXXXXXXXXXXXX 263
SD SAKLVPQFNQIAFFKV PGFSFHDVEEVKVDKHRLSIQGWYHI
Sbjct: 201 HSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVKVDKHRLSIQGWYHIPQVGEEGYIPGEE 260
Query: 264 XXWIKTNISTLSQLVNSPLQDYEFPKIDRTPLSHYE-----------------------S 300
W++ N STL+Q+ ++ L+D+EFPK +R LS +E
Sbjct: 261 EAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEVKHFEKMLKGDAGAKTDNTPKESM 320
Query: 301 GKXXXXXXXXXXXXXXFLSKFLNPEHLTTESMRKISDKFVEDSFINIESFLNDEYSSLLK 360
+LS++++PEHL+++ + K+ +FVE+S + IESFLND+ S LLK
Sbjct: 321 TSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVENSSLQIESFLNDDKSELLK 380
Query: 361 KLIMDKEFNYDCPYESVNVRHPWKTSLPPHKWRYLYIDGKSYTNFRNEEDIKKALNNPEL 420
K+I KE +CPY S +V+ PWKT++PPHK RYLYIDGK Y NF+ E DI +ALNN +L
Sbjct: 381 KVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQTEADILEALNNNDL 440
Query: 421 PNFH------QLLSSFAD---KEEFNCEAKLCELAIFLQSISFKKWIVQLTKLVILSEQL 471
PNF +++S + + F+ E L +LA+F +S FKK++ LT L +SEQ+
Sbjct: 441 PNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTSLCPVSEQI 500
Query: 472 LIRRFRPGKDFTLATTTEVNELLKTIPGFVEAILECTLCLTPSKGWDSGEVGGYELYM-- 529
LIRRFRPG DFTLAT NELLK+ P ++A+LE TLCLTPS GW+SGE+GGYELYM
Sbjct: 501 LIRRFRPGMDFTLATKCRFNELLKSNPDIIDAVLEGTLCLTPSAGWESGELGGYELYMMD 560
Query: 530 ----NNQ-XXXXXXXXXXXXXXXXXXSVLINKPASWNSLNLVLRDENVLQFIKYVSWAAK 584
N Q SVLIN P +WN+ NLVLRDE+VL+F+KYVSW+AK
Sbjct: 561 DDEDNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVLEFVKYVSWSAK 620
Query: 585 SSRWDISLQWDVKS 598
SSRWD+ ++WDVKS
Sbjct: 621 SSRWDVKMKWDVKS 634
>SPBC6B1.08c [B] KOG3844 Predicted component of NuA3 histone acetyltransferase
complex
Length = 515
Score = 381 bits (978), Expect = e-105
Identities = 220/561 (39%), Positives = 309/561 (54%), Gaps = 64/561 (11%)
Query: 39 DKSFQDDLRQEIKNAQPYNWGTIRDLVDPNLLQEVRREIETSIHFTQKETDIYKVNQSGD 98
D S + L +E PYN IR L++ LL+ VR+E+ +IHFT+K TDIY+V Q+GD
Sbjct: 19 DTSEAERLSREYHKNGPYNHVVIRPLINDTLLRNVRKELMENIHFTEKVTDIYRVWQTGD 78
Query: 99 LANLSGLDDADLSKLPSLVKLRELLYSEKYRDFIAYVTQSGKLSGSKTDISINTYTKGCH 158
LANL GLD + + L L ++R+ LYSE++R + +T G LS SK D+S+N Y+KGCH
Sbjct: 79 LANLDGLDKKEQNMLKYLRQVRDALYSEEFRSHVQKITGCGPLSASKKDLSVNVYSKGCH 138
Query: 159 LLTHDDVIGSRRVSFILYLPEPERVWKEHYGGGLRLFPSIVPNVPFSDHSAKLVPQFNQI 218
L+ HDDVIG+R +S+ILYL EP+ WK YGG LRLFP++ P+ P +D + PQ+NQ+
Sbjct: 139 LMNHDDVIGTRCISYILYLVEPDEGWKPEYGGALRLFPTLQPSFPAADFCHSIPPQWNQL 198
Query: 219 AFFKVQPGFSFHDVEEVKVDKHRLSIQGWYHIXXXXXXXXXXXXXXXWIKTNISTLSQLV 278
+FF+V+PG SFHDVEEV VDK R++I GW+H + +STL L
Sbjct: 199 SFFRVKPGHSFHDVEEVYVDKPRMAISGWFH----YPQPGEPGYDANYCDNTVSTLQSLT 254
Query: 279 NSPLQDYEFPKIDRTPLSHYESGKXXXXXXXXXXXXXXFLSKFLNPEHLTTESMRKISDK 338
+ D E P+ P+ E LS ++NP +LT + + K+S +
Sbjct: 255 MKQM-DLELPRFSYYPVVKPEP---------LSKQDTDILSNYINPLYLTPDGIEKLSKR 304
Query: 339 FVEDSFINIESFLNDEYSSLLKKLIMDKEFNYDCPYESVNVRHPWKTSLPPHKWRYLYID 398
F +DS I + FLN E+++ L K I+D E P S V PWKT++PPHK RYLY+D
Sbjct: 305 FFQDSVIVLVEFLNQEFANTLLKRIIDAE-RQPTPMHSSEVSFPWKTAIPPHKHRYLYLD 363
Query: 399 GKSYTNFRNEEDIKKALNNPELPNFHQLLSSFADKEEFNCEAKLCELAIFLQSISFKKWI 458
+ + DI ++ LP +F++WI
Sbjct: 364 HEEF-----GPDIILPMDLQRLP-------------------------------AFQRWI 387
Query: 459 VQLTKLVILSEQLLIRRFRPGKDFTLATTTEVNELLKTIPGFVEAILECTLCLTPSKGWD 518
++ L + S + RRFRPG DFTLATT + A+LE TLCL+P G
Sbjct: 388 QLVSGLPLRSFHQVGRRFRPGSDFTLATTNDT------------ALLEATLCLSPGTGIA 435
Query: 519 SGEVGGYELYMNNQXXXXXXXXXXXXXXXXXXSVLINKPASWNSLNLVLRDENVLQFIKY 578
+ + G Y++YM S+L++ PA+WN +LV RDE VLQF+KY
Sbjct: 436 NTDNGAYDIYMIGD-EDPDVDAAVYRGDQQDDSILLSLPAAWNVFSLVYRDEGVLQFVKY 494
Query: 579 VSWAAKSSRWDISLQWDVKSE 599
VS A+SSRWDI QW+ +E
Sbjct: 495 VSRQAESSRWDIYSQWNPVAE 515
>CE01785 [B] KOG3844 Predicted component of NuA3 histone acetyltransferase
complex
Length = 480
Score = 78.6 bits (192), Expect = 3e-14
Identities = 68/251 (27%), Positives = 122/251 (48%), Gaps = 21/251 (8%)
Query: 7 KRPAEETALGSDEKVRLLESSKAVGSFNSKIWDKSFQDDLRQEIKNA-----QPYNWGTI 61
KR ++ K L+ ++V I K +D + E K P+ +
Sbjct: 2 KRKSKAGGASDKSKSPKLKKRRSVVLEPIHISPKYLEDKFKTEFKKGFEKSNGPFPHWQL 61
Query: 62 RDLVD--PNLLQEVRREIETSIHFTQKETDIYKVNQSGDLANLSGLDDADLSKLPSLVKL 119
R+ VD N+++++ E++ + +KE D+Y + QS DL +++ +++ P++
Sbjct: 62 RNFVDNSDNVVEKIEDELQNFEGWKRKENDLYSLYQSDDLKSINPVEN------PAVFSF 115
Query: 120 RELLYSEKYRDFIAYVTQSGKLSGSKTDISINTYTKGCHLLTHDDVIGSRRVSFILYLPE 179
R+ LY E ++++ V SG + D + + Y + LL H+D+I +RR +F+ Y+
Sbjct: 116 RQFLYKE-VKEWLQNV--SGVELTEQVDCNGSCYARTDSLLPHNDLIETRRFAFVYYITS 172
Query: 180 PERVW-KEHYGGGLRLFPSIVPNVPFSDHSAKLVPQFNQIAFFKVQPGFSFHDVEEVKVD 238
+ W E GG L+LF P S +A+ P N F+V S+H V E+ +
Sbjct: 173 AD--WDSEVNGGDLQLFNHDKKLQPTS-VAAQFSPLRNSFMLFEVSEK-SWHRVAEMLSE 228
Query: 239 KHRLSIQGWYH 249
+ RLSI GW+H
Sbjct: 229 EPRLSINGWFH 239
>Hs8922694 [B] KOG3844 Predicted component of NuA3 histone acetyltransferase
complex
Length = 402
Score = 65.5 bits (158), Expect = 2e-10
Identities = 68/238 (28%), Positives = 97/238 (40%), Gaps = 62/238 (26%)
Query: 159 LLTHDDVIGSRRVSFILYLPEPERVWKEHYGGGLRLFPSIVPNVPFSDHSAKLVPQFNQI 218
LL HDD + RR++FILYL W GG L L+ SI + L+P +N++
Sbjct: 12 LLCHDDELEGRRIAFILYLVPS---WDRSMGGTLDLY-SIDEHFQPKQIVKSLIPSWNKL 67
Query: 219 AFFKVQPGFSFHDVEEV-KVDKHRLSIQGWYHIXXXXXXXXXXXXXXXWIKTNISTLSQL 277
FF+V P SFH V EV +K RLSI GW+H L
Sbjct: 68 VFFEVSP-VSFHQVSEVLSEEKSRLSISGWFH------------------------GPSL 102
Query: 278 VNSPLQDYEFPKIDRTPLSHYESGKXXXXXXXXXXXXXXFLSKFLNPEHLTTESMRKISD 337
P +Y P I R+P L ++NP +L + +I +
Sbjct: 103 TRPP--NYFEPPIPRSP---------------HIPQDHEILYDWINPTYLDMDYQVQIQE 145
Query: 338 KFVEDSFINIESFLNDEYSSLLKKLIMDKEFNYDCPYESVNVRH-PWKTSLPPHKWRY 394
+F E S I LLK+ + ++F C E++ H W + PP+K Y
Sbjct: 146 EFEESSEI------------LLKEFLKPEKFTKVC--EALEHGHVEWSSRGPPNKRFY 189
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,826,302
Number of Sequences: 60738
Number of extensions: 1446097
Number of successful extensions: 3551
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3535
Number of HSP's gapped (non-prelim): 8
length of query: 600
length of database: 30,389,216
effective HSP length: 112
effective length of query: 488
effective length of database: 23,586,560
effective search space: 11510241280
effective search space used: 11510241280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)