ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1160 suspect: Pn Z KOG0161 Cytoskeleton Myosin class II heavy chain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1160 407672 406767 -302
(302 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs17978507 [Z] KOG0161 Myosin class II heavy chain 54 2e-07
Hs20070146 [IT] KOG1118 Lysophosphatidic acid acyltransferase en... 52 1e-06
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 50 5e-06
>Hs17978507 [Z] KOG0161 Myosin class II heavy chain
Length = 1581
Score = 54.3 bits (129), Expect = 2e-07
Identities = 77/318 (24%), Positives = 138/318 (43%), Gaps = 37/318 (11%)
Query: 10 KKVQELSTSVS--------QKAQEAQLDQKFKDLKTNLPLLANSTQR--MLQEKLGQVTD 59
KK Q L+ + Q+ + +L++K + + L QR + +EKL + D
Sbjct: 972 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKD 1031
Query: 60 ISQLPDEYVQLEHRVETIKLIYENFLKVTKIYENESYDYPSNVKESVDEFSKL-VGGKLH 118
+ L E L+ ++E + F + E E D S +ES DE S V +L
Sbjct: 1032 M--LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS--QESKDEASLAKVKKQLR 1087
Query: 119 DL-SKVTNREQAQNVLLSSPQMKEPKTLNYALSKVALTSSEHVEDESLANFLAKYSDS-Q 176
DL +KV ++E+ + + QM E L + + + E ES + + S Q
Sbjct: 1088 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1147
Query: 177 TKIAQLRLQQDTMIQTKFNKAIKEKLEQDIETSTKA-----RKLVEQKRLQYDVVRS--- 228
K+ Q+ +Q + + K K ++EK E + + +T + R +KRL+ D+ R+
Sbjct: 1148 KKLKQMEVQLEEEYEDK-QKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1206
Query: 229 --------NRLKNTKPEKQAALQVEESTHEEEFAKATDDAIIAMSKV-VELADFSANLHE 279
+ LKN+ P K+ Q++ E EF A A+ A + VE+ D + +
Sbjct: 1207 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA--AVKARKAMEVEIEDLHLQIDD 1264
Query: 280 LVAAQLAYHKSSAEILEE 297
+ A+ A + + + E
Sbjct: 1265 IAKAKTALEEQLSRLQRE 1282
>Hs20070146 [IT] KOG1118 Lysophosphatidic acid acyltransferase endophilin/SH3GL
involved in synaptic vesicle formation
Length = 355
Score = 51.6 bits (122), Expect = 1e-06
Identities = 59/262 (22%), Positives = 117/262 (44%), Gaps = 37/262 (14%)
Query: 45 STQRMLQEKLGQVTDISQLPDEYVQLEHRVE-TIKLIYENFLKVTKIYE-NESYDYPSNV 102
++Q++ EK+ ++L DE++ +E +++ T K++ E K T+ + N +Y +
Sbjct: 20 TSQQLFSEKISGAEG-TKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYRAKLGM 78
Query: 103 KESVDEFSKLVGGKLHDLSKVTNREQAQNVLLSSPQMKEPKTLNYALSKVALTSSEHVED 162
+V K+ K T Q + LL +K K L ED
Sbjct: 79 LNTVS--------KIRGQVKTTGYPQTEG-LLGDCMLKYGKELG--------------ED 115
Query: 163 ESLANFLAKYSDSQTKIAQLRLQQDTMIQTKFNKAIKEKLEQDIETSTKARKLVEQKRLQ 222
+ N L + +S +A+++ D ++ F ++ ++D++ K +E +RL
Sbjct: 116 STFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLD 175
Query: 223 YDVVRSNRLKNTKPEKQAALQVEESTHEEEFAKATDDAIIA--MSKVVELADFSANLHEL 280
YD + K P+++ VE+ +E A+ + + + +V +LA F
Sbjct: 176 YDYKKKRVGK--IPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVF------- 226
Query: 281 VAAQLAYHKSSAEILEELVNEV 302
+ A L YH+ S EIL+EL +++
Sbjct: 227 IEAALDYHRQSTEILQELQSKL 248
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 49.7 bits (117), Expect = 5e-06
Identities = 70/301 (23%), Positives = 129/301 (42%), Gaps = 34/301 (11%)
Query: 6 DSFSKKVQELSTSVSQKAQE-AQLDQKFKDLKTNLPLLANSTQRM---LQEKLGQVT-DI 60
D ++ ELS + QE AQL+ K L+ LL + + L + G++ +
Sbjct: 881 DQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTGKLKIEE 940
Query: 61 SQLPDEYVQLEHRVETIKLIYENFLKVTKIYENESYDYPSNVKESVDEFSKLVGGKLHDL 120
S+ D +L R E I + E + ++ + S + E++ + SKL H
Sbjct: 941 SKSSDLGKKLTARQEEISNLKEENMSQSQAITSVK----SKLDETLSKSSKLEADIEHLK 996
Query: 121 SKVTNREQAQNVLLSSPQMKEPKTLNYALSKVALTSSEHVEDESLANFLAKYSDSQTKIA 180
+KV+ E +N LL+S +E + D+ L N + QT+I
Sbjct: 997 NKVSEVEVERNALLAS--------------------NERLMDD-LKNNGENIASLQTEIE 1035
Query: 181 QLRLQQDTMIQTKFNKAIKEKLEQDIETSTKARKLVEQKRLQYDVVRSNRLKNTKPEKQA 240
+ R + D + Q+K + + + E + S++ K +E K Q + N K + Q
Sbjct: 1036 KKRAENDDL-QSKLS-VVSSEYENLLLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQR 1093
Query: 241 ALQVEESTHEEEFAKATDDAIIAMSKVVELADFSANLHELVAAQLAYHKSSAEILEELVN 300
+++EE T ++ K ++ +++ L S H+L A + K ++ LE+L N
Sbjct: 1094 NVELEELT--SKYGKLGEENAQIKDELLALRKKSKKQHDLCANFVDDLKEKSDALEQLTN 1151
Query: 301 E 301
E
Sbjct: 1152 E 1152
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.308 0.124 0.313
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,219,315
Number of Sequences: 60738
Number of extensions: 597143
Number of successful extensions: 2861
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2859
Number of HSP's gapped (non-prelim): 5
length of query: 302
length of database: 30,389,216
effective HSP length: 106
effective length of query: 196
effective length of database: 23,950,988
effective search space: 4694393648
effective search space used: 4694393648
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)