ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1186 good S KOG2342 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1186 417098 416181 -306
(306 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR127w [S] KOG2342 Uncharacterized conserved protein 249 5e-66
CE24678 [S] KOG2342 Uncharacterized conserved protein 88 1e-17
Hs20561163 [S] KOG2342 Uncharacterized conserved protein 77 4e-14
CE12870 [S] KOG2342 Uncharacterized conserved protein 62 8e-10
>YGR127w [S] KOG2342 Uncharacterized conserved protein
Length = 312
Score = 249 bits (635), Expect = 5e-66
Identities = 143/320 (44%), Positives = 193/320 (59%), Gaps = 24/320 (7%)
Query: 1 MCILFATRAHPDYKLILLSNRDEFFERKTHATCWNHDGFILSPYDMA-IEKKGQGYGTWL 59
MCIL ATRAHPDY+LIL+SNRDEF RKTHATCW+++ FILSPYD+A + Q +GTW
Sbjct: 1 MCILMATRAHPDYELILISNRDEFLARKTHATCWHNNDFILSPYDLAKTSAEKQIFGTWS 60
Query: 60 GINRRGRIAVILNLKIDSPLDSESVLVNGEPRSRGIVPLQFLQQEDNAPFDNWDSWEKFN 119
GIN+ G++A ILNLK+D+ + N + RSRG++P FL A F++WD+++KF
Sbjct: 61 GINKEGKLATILNLKLDNEQN------NTKSRSRGLLPFIFLSIH-KADFEDWDNYKKFE 113
Query: 120 GQHGNLRRTGPFTLFYGDAKSDEYNVIDYLKH------STNPFEKMEHMVISNDIFHCAV 173
G + L+ TG F FYGD +Y VID L ST + +MV+SN F+ +
Sbjct: 114 GHYDGLKSTGDFNFFYGDVIKKQYKVIDSLGRTFDVLSSTCRKDLDSYMVVSNGKFYDSS 173
Query: 174 GEHTSRWNKTEYGYVLLDALAKNTTGIAKEELLQKCFELLSNHTFN---EGEDV-----D 225
W K + L+ L +E+++ CF+L S + DV
Sbjct: 174 SIPGQAWEKVKVARDSLENLVLENIESDEEKIISSCFQLASKSSLPSTISNPDVLQMVDP 233
Query: 226 SVTTSSIYVPPLRITKGADAIGTSLPIGDYYGTRSQIVILVDKDN-RVTYEEHVIYESDE 284
+VT ++IYVPPLR D +G S+P GDYYGTRSQIV+LV KD+ RVT+ E V+Y SDE
Sbjct: 234 NVTMNTIYVPPLR-RPPRDDLGASIPDGDYYGTRSQIVLLVSKDSTRVTFIERVLYSSDE 292
Query: 285 DCETYSFMDPKEVIQFQFNM 304
D YS PKE +F+F +
Sbjct: 293 DVRKYSVTSPKEEKRFKFKL 312
>CE24678 [S] KOG2342 Uncharacterized conserved protein
Length = 279
Score = 88.2 bits (217), Expect = 1e-17
Identities = 87/301 (28%), Positives = 134/301 (43%), Gaps = 34/301 (11%)
Query: 1 MCILF---ATRAHPDYKLILLSNRDEFFERKTHATCWNHDGFILSPYDMAIEKKGQGYGT 57
MCI F AT YKLI+L+NRDE +R T W HDG + +++K GT
Sbjct: 1 MCIGFIKIATSPSEKYKLIILNNRDEDLDRPTTPIHW-HDGML-----SGVDEKDVARGT 54
Query: 58 WLGINRRGRIAVILNLKIDSPLDSESVLVNGEPRSRGIVPLQFLQQEDNAPF--DNWDSW 115
WLG++ G++ ++L+ I P+DS+ P GIV D F + ++
Sbjct: 55 WLGMDAHGKVGMLLS--ITQPVDSKH---KNAPSRGGIVNEYLKSGTDTTKFYENLRENA 109
Query: 116 EKFNGQHGNLRRTGPFTLFYGDAKSDEYNVIDYLKHSTNPFEKMEHMVISNDIFHCAVGE 175
EKFNG F G K+ + +++ TN + ND FH
Sbjct: 110 EKFNGFQ-----------FVGVEKNPTTGLF-HVQSLTNQLVDQIEISKWNDKFHVFSNS 157
Query: 176 HTS-RWNKTEYGYVLLDALAKNTTGIAKEELLQKCFELLSNHTFNEGEDVDSVTTSSIYV 234
+ KTE+G + + KNT ++ E++ +K FE+ + T +D T
Sbjct: 158 PPHVPFKKTEFGLKMFEEKLKNTDEMSVEQIFEKLFEIATCRTSCFPDDQIRAQTGF--- 214
Query: 235 PPLRITKGADAIGTSLPIGDYYGTRSQIVILVDKDNRVTYEEHVIYESDEDCETYSFMDP 294
P I K +I P YGTRS +I+VD++ +VT + + E E E ++ D
Sbjct: 215 -PEHIYKPLTSIFVRFPEIRRYGTRSHTLIVVDQNGQVTVLDRRM-EPAESVEESTWHDE 272
Query: 295 K 295
K
Sbjct: 273 K 273
>Hs20561163 [S] KOG2342 Uncharacterized conserved protein
Length = 317
Score = 76.6 bits (187), Expect = 4e-14
Identities = 79/283 (27%), Positives = 131/283 (45%), Gaps = 32/283 (11%)
Query: 13 YKLILLSNRDEFFERKTH-ATCWNHDGFILSPYDMAIEKKGQGYGTWLGINRRGRIAVIL 71
++LIL +NRDEF+ R + A W ++ ILS DM K+G GTWLGI+ RG++A +
Sbjct: 59 HRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEG---GTWLGISTRGKLAALT 115
Query: 72 NLKIDSPLDSESVLVNGEPRSRGIVPLQFLQQEDNAPFDNWDSWEKFNGQHGNLRRTGPF 131
N + LD ++ R RG + FL + ++ S+ K G+L F
Sbjct: 116 NY-LQPQLDWQA-------RGRGELVTHFLTTDVDSL-----SYLKKVSMEGHLYNG--F 160
Query: 132 TLFYGDAKSDEYNVIDYLKHSTNPFEKMEHMVISNDIFHCAVGEHTSRWNKTEYGYVLLD 191
L D + + +VI Y + P + +V++ + + + W K +G L
Sbjct: 161 NLIAADLSTAKGDVICYYGNRGEP----DPIVLTPGTYGLSNALLETPWRKLCFGKQLFL 216
Query: 192 ALAKNTTGIAKEELLQKCFELLSNHTFNEGEDVDSVTTSSIYVPPLRITKGADAIGTSLP 251
+ + + K+ L+ ++L+N + D YV P+ ++K A A+ P
Sbjct: 217 EAVERSQALPKDVLIASLLDVLNNEEA-QLPDPAIEDQGGEYVQPM-LSKYA-AVCVRCP 273
Query: 252 IGDYYGTRSQIVILVDKDNRVTYEEHVIYESD---EDCETYSF 291
YGTR+ +ILVD D VT+ E + + D + TY F
Sbjct: 274 ---GYGTRTNTIILVDADGHVTFTERSMMDKDLSHWETRTYEF 313
>CE12870 [S] KOG2342 Uncharacterized conserved protein
Length = 276
Score = 62.4 bits (150), Expect = 8e-10
Identities = 78/287 (27%), Positives = 117/287 (40%), Gaps = 44/287 (15%)
Query: 1 MCILFATRAHPD---YKLILLSNRDEFFERKTHATCWNHDGFILSPYDMAIEKKGQGYGT 57
MCI F A YKLILL+NRDE R T W HDG + ++K+ GT
Sbjct: 1 MCITFIKTAKSSLDKYKLILLNNRDEQLLRPTKEMHW-HDGIL-----SGVDKQENARGT 54
Query: 58 WLGINRRGRIAVILNLKIDSPLDSESVLVNGEPRSRGIVPLQFLQQEDNAPFDNWDSWEK 117
WLG+N GRI ++L+ I +S+ N SRG + +FL D + +S +K
Sbjct: 55 WLGLNENGRIGMMLS--ITQTQESK----NLHAPSRGGIVNEFLNANDTSKM--IESLKK 106
Query: 118 FNGQHGNLRRTGPFTLFYGDAKSDE-YNVIDYLKHSTNPFE----KMEHMVISNDIFHCA 172
++ F L + S Y V + E K E+ V+SN
Sbjct: 107 CASKYNG------FQLVAVEKNSTGLYEVRTLANQQVDEIEVCQLKDEYHVVSN------ 154
Query: 173 VGEHTSRWNKTEYGYVLLDALAKNTTGIAKEELLQKCFELLSNHT--FNEGEDVDSVTTS 230
T + K G LL +N+ + +++ +K + N T + + +
Sbjct: 155 -SPPTKPYQKAVQGKKLLREHLENSDQFSVDQIFEKLLSIAKNTTQWYPDAQLQYQTQNV 213
Query: 231 SIYVPPLRITKGADAIGTSLPIGD-YYGTRSQIVILVDKDNRVTYEE 276
Y PL AI P G YGTR +I VD+ +++ E
Sbjct: 214 EEYNRPL------SAIFIKYPEGTRMYGTRCHTLITVDQKDKINILE 254
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,339,396
Number of Sequences: 60738
Number of extensions: 921207
Number of successful extensions: 1967
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1953
Number of HSP's gapped (non-prelim): 4
length of query: 306
length of database: 30,389,216
effective HSP length: 106
effective length of query: 200
effective length of database: 23,950,988
effective search space: 4790197600
effective search space used: 4790197600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)