ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1318 good K KOG1920 Transcription IkappaB kinase complex, IKAP component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1318 460483 464457 1325
(1325 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR384c [K] KOG1920 IkappaB kinase complex IKAP component 1853 0.0
SPBC36.07 [K] KOG1920 IkappaB kinase complex IKAP component 735 0.0
Hs15298985 [K] KOG1920 IkappaB kinase complex IKAP component 447 e-125
Hs4504629 [K] KOG1920 IkappaB kinase complex IKAP component 445 e-124
7299482 [K] KOG1920 IkappaB kinase complex IKAP component 216 1e-55
CE28103 [K] KOG1920 IkappaB kinase complex IKAP component 170 1e-41
At5g13680 [K] KOG1920 IkappaB kinase complex IKAP component 164 7e-40
>YLR384c [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1349
Score = 1853 bits (4800), Expect = 0.0
Identities = 902/1333 (67%), Positives = 1101/1333 (81%), Gaps = 9/1333 (0%)
Query: 1 MRNLITLNHGKLQPVSQTLPDLE------LYTSCFDTLSDSITCVLGAADIGALEVQQYM 54
MRNLITLN GK +P + T E L S FDTLSDSITCVLG+ DIGA+EVQQ+M
Sbjct: 18 MRNLITLNKGKFKPTASTAEGDEDDLSFTLLDSVFDTLSDSITCVLGSTDIGAIEVQQFM 77
Query: 55 KDGSMNVLASFYVQSYNDKLLSFIHFDDINELVFVFQQGDIISVTYDPATMDYHSSKVSI 114
KDGS NVLASF +Q+++DKLLSF+HF DIN+LVFVF+QGDII+ TYDP ++D + + I
Sbjct: 78 KDGSRNVLASFNIQTFDDKLLSFVHFADINQLVFVFEQGDIITATYDPVSLDPAETLIEI 137
Query: 115 VGSIDLGIEAAEWSADQETLAIVTFERNVVLLSRQLEPIVETSLQVEDLKISKHVTVGWG 174
+G+ID GI AA+WS D+ETLA+VT +RNVV+LS+ EPI E L+V+DLKISKHVTVGWG
Sbjct: 138 MGTIDNGIAAAQWSYDEETLAMVTKDRNVVVLSKLFEPISEYHLEVDDLKISKHVTVGWG 197
Query: 175 KKDTQFRGKGARAMEREALESLKASGLVGNELRDPTMPYRVDTGAITELDSRKVKISWRG 234
KK+TQFRGKGARAMEREAL SLKASGLVGN+LRDPTMPY VDTG +T LDS ++ ISWRG
Sbjct: 198 KKETQFRGKGARAMEREALASLKASGLVGNQLRDPTMPYMVDTGDVTALDSHEITISWRG 257
Query: 235 DCEYFAVTTIETVKDPSDESKTVERRALRVFTRDGQLDSASEPVDGMNEHLSWKPQGSLI 294
DC+YFAV+++E V D DE+K+++RRA RVF+R+GQLDSASEPV GM LSWKPQGSLI
Sbjct: 258 DCDYFAVSSVEEVPDEDDETKSIKRRAFRVFSREGQLDSASEPVTGMEHQLSWKPQGSLI 317
Query: 295 ASVQRKTHIPDEEGLDLIFFERNGLRHGEFDLRLPSDEPVLDLCWNANSEILTIVLIDRV 354
AS+QRKT + +E+ +D+IFFERNGLRHGEFD RLP DE V +CWN+NSE L +VL +R+
Sbjct: 318 ASIQRKTDLGEEDSVDVIFFERNGLRHGEFDTRLPLDEKVESVCWNSNSEALAVVLANRI 377
Query: 355 QLWTTKNYHWFLKQEFYFNNITYAKWHPEKDFTLMVGDSEKMTIVDFAYKMTAGPTMQPF 414
QLWT+KNYHW+LKQE Y ++I+Y KWHPEKDFTLM D+ + IVDFAYKM GPT++PF
Sbjct: 378 QLWTSKNYHWYLKQELYASDISYVKWHPEKDFTLMFSDAGFINIVDFAYKMAQGPTLEPF 437
Query: 415 DNGTSIVIDGNVVNITPLGIANVPPPLYFRDFECPNNVLDAACSVSNEVYAAITKDELVI 474
DNGTS+V+DG VNITPL +ANVPPP+Y+RDFE P NVLD ACS SNE+YAAI KD L+
Sbjct: 438 DNGTSLVVDGRTVNITPLALANVPPPMYYRDFETPGNVLDVACSFSNEIYAAINKDVLIF 497
Query: 475 ASVPSLKAMKNGKHPWIVSTFNKSSFGTAFDTLRQLAFINDNTVAILLDTDNLSRIALID 534
A+VPS++ MK GKHP IV F KS F + D+LRQ+AFIND+ V +LLDTDNLSRIAL+D
Sbjct: 498 AAVPSIEEMKKGKHPSIVCEFPKSEFTSEVDSLRQVAFINDSIVGVLLDTDNLSRIALLD 557
Query: 535 ITDNTNPSLITIIETFDKVVLLRSQFDYNFVVFETRDGKITQLSADGQLSTITRFPQLVY 594
I D T P+LITI+E +DK+VLLRS FDYN +V+ETRDG + QL A+GQL IT+FPQLV
Sbjct: 558 IQDITQPTLITIVEVYDKIVLLRSDFDYNHLVYETRDGTVCQLDAEGQLMEITKFPQLVR 617
Query: 595 DFRVKRVESATAAND--WGDEQSKTVAFGLTNTGKLFANEVQLTSAVTSIEITDSFLLFT 652
DFRVKRV + +A +D W E S+ VAFG+TN GKLFAN+V L SAVTS+EITDSFLLFT
Sbjct: 618 DFRVKRVHNTSAEDDDNWSAESSELVAFGITNNGKLFANQVLLASAVTSLEITDSFLLFT 677
Query: 653 TAQHNLQFIHLNTTDYKPLATVEDDTIDERVRAVERGSILVNVIPSKAAVILQAARGNLE 712
TAQHNLQF+HLN+TD+KPL VE+ DERVRA+ERGSILV+VIPSK++V+LQA RGNLE
Sbjct: 678 TAQHNLQFVHLNSTDFKPLPLVEEGVEDERVRAIERGSILVSVIPSKSSVVLQATRGNLE 737
Query: 713 TIYPRIMVLSGVRANIIAKNYKEAFVTCRTHRINLDILYDYDPELFLNNLPHFITEIERV 772
TIYPRIMVL+ VR NI+AK YKEAF+ CRTHRINLDIL+DY PELF+ NL FI +I RV
Sbjct: 738 TIYPRIMVLAEVRKNIMAKRYKEAFIVCRTHRINLDILHDYAPELFIENLEVFINQIGRV 797
Query: 773 DYLDLFISSLLEDDVTKTKYRETLNFDSSTAFDVAPPPPTEMQLYMKKKMFNPKTSKVNK 832
DYL+LFIS L EDDVTKTKY+ETL S +F + P P TEMQ+YMKKKMF+PKTSKVNK
Sbjct: 798 DYLNLFISCLSEDDVTKTKYKETLYSGISKSFGMEPAPLTEMQIYMKKKMFDPKTSKVNK 857
Query: 833 VCQAILDVLLNTPNFRQKYLQSIITAYACQNPPNLRDALQLIDTVESEEQKDSTVTYLCF 892
+C A+L+VLL+ P +++KYLQ+IITAYA QNP NL AL+LI +E+ E+KDS VTYLCF
Sbjct: 858 ICDAVLNVLLSNPEYKKKYLQTIITAYASQNPQNLSAALKLISELENSEEKDSCVTYLCF 917
Query: 893 LQDVNVIYKVALSLYDIHLTLAVAQKSQMDPREYLPFLQSLLDAEPLRRKFMIDDYLQNY 952
LQDVNV+YK ALSLYD+ L L VAQKSQMDPREYLPFLQ L D EPLRRKF+IDDYL NY
Sbjct: 918 LQDVNVVYKSALSLYDVSLALLVAQKSQMDPREYLPFLQELQDNEPLRRKFLIDDYLGNY 977
Query: 953 ELAIEHLAAIDKVDNTVSSEFIEYVEEHDLFKHALNIFKSEQDRQNIIYHVYAKSLSSQQ 1012
E A+EHL+ IDK D VS E I+YVE HDL+KH L +++ + ++QN+IY++YAK LSS Q
Sbjct: 978 EKALEHLSEIDK-DGNVSEEVIDYVESHDLYKHGLALYRYDSEKQNVIYNIYAKHLSSNQ 1036
Query: 1013 QYGDAGIIHEMLGEWKEALDAYTLGKKWNEAMSVVLDHFPDKTEDIATELISSLTFEHRY 1072
Y DA + +EMLG+ KEA+ AY K+W EAMS+ + FP++ E +A ELISSLTFEHRY
Sbjct: 1037 MYTDAAVAYEMLGKLKEAMGAYQSAKRWREAMSIAVQKFPEEVESVAEELISSLTFEHRY 1096
Query: 1073 VDASQLEIRFMKNIKAGMDLLCRAYDYEAASLIAIAEHKSELIEEIVDPALGDGFGTIAE 1132
VDA+ +++ ++ N+K + L C+AY Y+ ASL+AI K EL+EE+VDP LG+GFG IAE
Sbjct: 1097 VDAADIQLEYLDNVKEAVALYCKAYRYDIASLVAIKAKKDELLEEVVDPGLGEGFGIIAE 1156
Query: 1133 LLADCKGQVNSQLKRLRELRQKKAEDPFAFYGEETDQADDVSIAASETSTKESFFTRYXX 1192
LLADCKGQ+NSQL+RLRELR KK E+P+AFYG+ET+QADDVS+A SETST+ESFFTRY
Sbjct: 1157 LLADCKGQINSQLRRLRELRAKKEENPYAFYGQETEQADDVSVAPSETSTQESFFTRYTG 1216
Query: 1193 XXXXXXXXXXXRKTAKNKRRQERKRARGKKGTIYEEEYLIQSIGRLIDRLYQTQPEAIKL 1252
R+TAKNKRR+ERKRARGKKGTIYEEEYL+QS+GRLI+RL QT+P+A+++
Sbjct: 1217 KTGGTAKTGASRRTAKNKRREERKRARGKKGTIYEEEYLVQSVGRLIERLNQTKPDAVRV 1276
Query: 1253 IEGLLRRNKREQAYQIQKNFMELIDLLKENVQEIYSISEKDRERIDDDGQVYYLPEIPVP 1312
+EGL RRN REQA+QIQKNF+E++DLLK NV+EIYSISEKDRER++++G+VYY+PEIPVP
Sbjct: 1277 VEGLCRRNMREQAHQIQKNFVEVLDLLKANVKEIYSISEKDRERVNENGEVYYIPEIPVP 1336
Query: 1313 EIKEFPKRNIVDF 1325
EI +FPK +IVDF
Sbjct: 1337 EIHDFPKSHIVDF 1349
>SPBC36.07 [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1253
Score = 735 bits (1898), Expect = 0.0
Identities = 463/1344 (34%), Positives = 717/1344 (52%), Gaps = 113/1344 (8%)
Query: 1 MRNLITLNHGKLQPVSQTLPDLELYTSCFDTLSDSITCVLGAADIG-ALEVQQYMKDGSM 59
M+NL+T H V+ ++ L F+++SD I V G + +E+ + ++ +
Sbjct: 1 MKNLVTHLHHVFPNVNGSIKAL-----AFNSISDKIYVVCGLDNENPGIEIYEISENDDV 55
Query: 60 NVLASFYVQSYN------DKLLSFIHFDDINELVFVFQQGDIISVTYDPATMDYHSSKVS 113
+ L F S+ D++ S + + + GDI+ V DP+ + +
Sbjct: 56 SKLVEFDSPSFVSDNGDIDEIQSMQFLGEPMAICLSLKGGDIVMVKVDPSPEE---APWE 112
Query: 114 IVGSIDLGIEAAEWSADQETLAIVTFERNVVLLSRQLEPIVETSLQVEDL-KISKHVTVG 172
I+G+++ GI A+ WS D++ I+T ++ +++ + I ETSL DL + +KH++VG
Sbjct: 113 IIGNVENGIVASCWSTDEQVFCIITGGDTILFMTKNFDIISETSLSDADLNEFNKHISVG 172
Query: 173 WGKKDTQFRGKGARAMEREALESLKASGLVGNELRDPTMPYRVDTGAITELDSRKVKISW 232
WG+ +TQFRGK RA +LRDPT+P ++D G ++++D K I W
Sbjct: 173 WGRSETQFRGKRVRA-----------------KLRDPTLPEKIDEGKLSDVDDGKTYICW 215
Query: 233 RGDCEYFAVTTIETVKDPSDESKTVERRALRVFTRDGQLDSASEPVDGMNEHLSWKPQGS 292
RGD +Y ++ +E K P RRA+RV++R+G LDS SEP DG LSWKP GS
Sbjct: 216 RGDSQYVSINRLE--KGP--------RRAIRVYSREGLLDSISEPQDGQQSLLSWKPSGS 265
Query: 293 LIASVQRKTHIPDEEGLDLIFFERNGLRHGEFDLRLPSDEPVLDLCWNANSEILTIVLID 352
++A+++ + + +IFFERNGLRHGEF LR DE L WN +S IL + +
Sbjct: 266 VLATIKSDS---SDNSSKVIFFERNGLRHGEFSLRRREDEKYTGLAWNVSSSILAVSTEN 322
Query: 353 RVQLWTTKNYHWFLKQEFYFNNITYAKWHPEKDFTLMVGDSEKMTIVDFAYKMTAGPTMQ 412
V LWTT NYHW+LK+E WHPE TL + + V F K +
Sbjct: 323 SVMLWTTGNYHWYLKKEINIPQNALISWHPEHANTLYITGKNHIEKVVFDLKYVTEFSTS 382
Query: 413 PFDNGTSIVIDGNVVNITPLGIANVPPPLYFRDFECPNNVLDAACSVSNEVYAAITKDEL 472
P D G VIDG+ + +TPL + N+PPP+ NV + + ++++ A L
Sbjct: 383 PNDFGLIPVIDGSSLLVTPLSLCNIPPPMCRYKLSLDYNVQMTSINATSDMLFAADDRRL 442
Query: 473 VIASVPSLKAMKNGKHPWIVSTFNKSSFGTAFDTLRQLAFINDNTVAILLD-TDNLSRIA 531
+ S + + F+ S++ + + L ++ N V +L D T+N S+
Sbjct: 443 TAFTFNSQEDIAK------FGEFDISTYAEGLN-FKSLLGLSGNQVLLLADGTNNCSKFF 495
Query: 532 LIDITDNTNPSLITIIETFDKVVLLRSQFDYNFVVFETRDGKITQ--LSADGQLSTITRF 589
+ ++ + E+F+ +L + + + F+T GK+ L+ S F
Sbjct: 496 VFQCDEDNESLKLLASESFESCIL-NASYCSEMLFFQTSSGKLISYNLNVKSIESISLSF 554
Query: 590 PQLVYDFRVKRVESATAANDWGDEQSKTVAFGLTNTGKLFANEVQLTSAVTSIEITDSFL 649
P+ DF V V V GLT+ G+L+A + L++ V S T+ F+
Sbjct: 555 PKPCSDFVVVPVHETF------------VPIGLTSYGRLYAEQRLLSTGVLSFFCTERFV 602
Query: 650 LFTTAQHNLQFIHLNTTDYKPLATVEDDTID---ERVRAVERGSILVNVIPSKAAVILQA 706
LFTT ++ L+F+HL +T L VEDD +D ER R VERGS +V +PSK AV+LQ
Sbjct: 603 LFTTTKNLLKFVHLVST-VDDLQVVEDDAVDRHDERCRVVERGSKIVASMPSKMAVVLQM 661
Query: 707 ARGNLETIYPRIMVLSGVRANIIAKNYKEAFVTCRTHRINLDILYDYDPELFLNNLPHFI 766
RGNLETIYPRIMVL GVR I A Y +AF CRTHR++L+IL+DYDP+LFL N+P F+
Sbjct: 662 PRGNLETIYPRIMVLDGVRTYIKALKYGDAFKVCRTHRLDLNILFDYDPDLFLKNIPVFV 721
Query: 767 TEIERVDYLDLFISSLLEDDVTKTKYRETLNFDSSTAFDVAPPPPTEMQLYMKKKMFNPK 826
+ RVDYLDLF++SL ++VT Y +T S +
Sbjct: 722 DGLYRVDYLDLFLTSLKPENVTTGMYSDTSKSQSQQSVTTI------------------- 762
Query: 827 TSKVNKVCQAILDVLLNTPNFRQKYLQSIITAYACQNPPNLRDALQLIDTV--ESEEQKD 884
+KVN +C+ I + L T + + Q+IIT+Y C++PP + AL +I + E D
Sbjct: 763 DNKVNLLCKIIREHL--TSKYGDTHFQAIITSYLCESPPKIEAALGMISGLIKAQSETVD 820
Query: 885 STVTYLCFLQDVNVIYKVALSLYDIHLTLAVAQKSQMDPREYLPFLQSLLDAEPLRRKFM 944
+ ++CFL DVN+++ AL LYD+ L L +AQ+SQ DPREY+PFL E LRRKF
Sbjct: 821 LAIEHMCFLVDVNMLFDHALGLYDLKLALLIAQQSQKDPREYVPFLHEFQKQESLRRKFN 880
Query: 945 IDDYLQNYELAIEHLAAIDKVDNTVSSEFIEYVEEHDLFKHALNIFKSEQDRQNIIYHVY 1004
ID YL+ YE A+ HL ++ EF + +H L+ AL ++K +++ Q + ++
Sbjct: 881 IDCYLKRYERALGHLKEME----NAFDEFKNFTIQHKLYPRALELYKYDKEAQKEVLIIF 936
Query: 1005 AKSLSSQQQYGDAGIIHEMLGEWKEALDAYTLGKKWNEAMSVV--LDHFPDKTEDIATEL 1062
A+ L + +A I +E +G+ EA++AY W E +S++ + D + A +L
Sbjct: 937 AQYLRENGKSNEAAIAYESVGKISEAIEAYKSAGMWRECLSILQQTTNSEDLIRETAEDL 996
Query: 1063 ISSLTFEHRYVDASQLEIRFMKNIKAGMDLLCRAYDYEAASLIAIAEHKSELIEEIVDPA 1122
S + + DA + + ++ N + + +C+ Y A IA A S + ++++
Sbjct: 997 ASLCIEKREHCDAGSINLLYLSNPREAVIQMCKGSQYSEAIRIARATGDSSIYKDLLISV 1056
Query: 1123 LGDGFGTIAELLADCKGQVNSQLKRLRELRQKKAEDPFAFY-GEETDQA-DDVSIAASET 1180
LG+ FG +EL+AD + Q+ SQ +R+ LR+KK EDP ++ G DQ DD+S+A++
Sbjct: 1057 LGESFGEASELVADFRNQIKSQTERILVLREKKKEDPISWMEGTMEDQTPDDISLASTSL 1116
Query: 1181 STKESFFTRYXXXXXXXXXXXXXRKTAKNKRRQERKRARGKKGTIYEEEYLIQSIGRLID 1240
ST S +T+Y R T+KN RR ERKRARGKKGT++EEEYL+ S+ RLI
Sbjct: 1117 STNRSLYTQY---TKSSNSSKMTRNTSKNNRRLERKRARGKKGTVFEEEYLVNSLRRLIA 1173
Query: 1241 RLYQTQPEAIKLIEGLLRRNKREQAYQIQKNFMELIDLLKENVQEIYSISEKDRERIDDD 1300
R+ + +PE +L+E L+R N QA ++Q+NF +I + E V I S+ E +
Sbjct: 1174 RVEEIRPEVHRLLEALVRCNMTTQASELQRNFANVIGTIGEKVIPILSVPVSTFETALGE 1233
Query: 1301 GQVYYLPEIP-VPEIKEFPKRNIV 1323
P+ P VP +K F K +I+
Sbjct: 1234 -----QPQAPVVPNVKPFEKLSIL 1252
>Hs15298985 [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1332
Score = 447 bits (1149), Expect = e-125
Identities = 358/1351 (26%), Positives = 607/1351 (44%), Gaps = 184/1351 (13%)
Query: 28 CFDTLSDSITCVLGAADIGALEVQ---QYMKDGSMNVLASFYVQSYNDKLLSFIHFDDIN 84
CF ++ T ++G+ + G +EV + +K+ V F + + +++ D
Sbjct: 23 CFSLRTEQGTVLIGS-EHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQE 81
Query: 85 ELVFVFQQGDIISVTYDPATMDYHSSKVSIVGSIDLGIEAAEWSADQETLAIVTFERNVV 144
+ GD+I + + ++ VGS+ GI WS DQE + + T ++ ++
Sbjct: 82 SVCVATASGDVILCSLS-------TQQLECVGSVASGISVMSWSPDQELVLLATGQQTLI 134
Query: 145 LLSRQLEPIVETSLQVEDLKISKHVTVGWGKKDTQFRGKGARAMEREALESLKASGLVGN 204
++++ EPI+E + +D SK +TVGWG+K+TQF G R +
Sbjct: 135 MMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAFQM------------ 182
Query: 205 ELRDPTMPYRVDTGAITELDSRKVKISWRGDCEYFAVTTIETVKDPSDESKTVERRALRV 264
++ + +P+ D + +++WRGD ++FAV+ + R +RV
Sbjct: 183 QMHESALPW----------DDHRPQVTWRGDGQFFAVSVV---------CPETGARKVRV 223
Query: 265 FTRDGQLDSASEPVDGMNEHLSWKPQGSLIASVQRKTHIPDEEGLDLIFFERNGLRHGEF 324
+ R+ L S SEPV G+ L+WKP GSLIAS Q K P+++ D++FFE+NGL HG F
Sbjct: 224 WNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDK---PNQQ--DIVFFEKNGLLHGHF 278
Query: 325 DLRLPSDE-PVLDLCWNANSEILTIVLIDR-----------VQLWTTKNYHWFLKQEFYF 372
L DE V DL WNA+S +L + L D VQLWT NYHW+LKQ F
Sbjct: 279 TLPFLKDEVKVNDLLWNADSSVLAVWLEDLQREESSIPKTCVQLWTVGNYHWYLKQSLSF 338
Query: 373 NNITYAK-----WHPEKDFTLMV-GDSEKMTIVDFAYKMTAGPTMQPFDNGTSIVIDGNV 426
+ +K W P + L V D+ + D VIDGN
Sbjct: 339 STCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNR 398
Query: 427 VNITPLGIANVPPPLYFRDFECPNNVLDAACSVSNEVYAAITKDELVIASVPSLKAMKNG 486
V +T VPPP+ P+ V V+ + + D V+ + + K G
Sbjct: 399 VLVTVFRQTVVPPPMCTYQLLFPHPVNQ----VTFLAHPQKSNDLAVLDASNQISVYKCG 454
Query: 487 KHPWIVSTFNKSSFGTAFDTLRQLAFINDNTVAILLDTDNLSRIALIDITDN----TNP- 541
P + D +L + + + L T +L + I +N NP
Sbjct: 455 DCP-------------SADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPL 501
Query: 542 --SLITIIETFDKVVLLRSQFDYNFVVFETR---------------------DGKITQLS 578
L+T IE + + S+F V+ DG I L
Sbjct: 502 KLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLC 561
Query: 579 ADGQLSTITRFPQLVYDFRVKRVESATAANDWGDEQSKTVAF------------------ 620
+ + ++ F+ + A W + V F
Sbjct: 562 CNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECV 621
Query: 621 -GLTNTGKLFANEVQLTSAVTSIEITDSFLLFTTAQHNLQFIHLNTTDYKPL-ATVEDDT 678
GLT+ + F N++++ S +TS + D FLL TT H Q L +K L A + +
Sbjct: 622 LGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNH 681
Query: 679 ID--ERVRAVERGSILVNVIPSKAAVILQAARGNLETIYPRIMVLSGVRANIIAKNYKEA 736
+ E +R VERGS +V V+P ++LQ RGNLE ++ R +VL+ +R + +KEA
Sbjct: 682 VSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEA 741
Query: 737 FVTCRTHRINLDILYDYDPELFLNNLPHFITEIERVDYLDLFISSLLEDDVTKTKYRETL 796
F R RINL+++YD++P++FL N+ FI +I+ V++++LF + L E+DVTKT Y
Sbjct: 742 FECMRKLRINLNLIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMY---- 797
Query: 797 NFDSSTAFDVAPPPPTEMQLYMKKKMFNPKTSKVNKVCQAILDVLLNTPNFRQKYLQSII 856
P P +Y+ + +P +K++ VC A+ V+ + KY SI+
Sbjct: 798 ------------PAPVTSSVYLSR---DPDGNKIDLVCDAMRAVMESIN--PHKYCLSIL 840
Query: 857 TAYACQNPPNLRDALQLIDTVESEEQKD-------STVTYLCFLQDVNVIYKVALSLYDI 909
T++ + P L LQ + ++ D + YL L DVN +Y +L YD
Sbjct: 841 TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF 900
Query: 910 HLTLAVAQKSQMDPREYLPFLQSLLDAEPLRRKFMIDDYLQNYELAIEHLAAIDKVDNTV 969
L L VA+KSQ DP+EYLPFL +L E ++F ID YL+ YE AI HL+ K
Sbjct: 901 DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLS---KCGPEY 957
Query: 970 SSEFIEYVEEHDLFKHALNIFKSEQDRQNIIYHVYAKSLSSQQQYGDAGIIHEMLGEWKE 1029
E + +++ +L+ AL ++ + I Y + L + Y AG++ G ++
Sbjct: 958 FPECLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEK 1017
Query: 1030 ALDAYTLGKKWNEAMSVV--LDHFPDKTEDIATELISSLTFEHRYVDASQLEIRFMKNIK 1087
AL A+ W +A+ V L+ D+ + L L + +++DA+ + ++ +
Sbjct: 1018 ALSAFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYE 1077
Query: 1088 AGMDLLCRAYDYEAASLIAIAEHKSELIEEIVDPALGDGFGTIAELLADCKGQVNSQLKR 1147
+ LL +E A + ++ ++IE V P++ + L + KR
Sbjct: 1078 EAVLLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKR 1137
Query: 1148 LRELRQKKAE------DPFAFYGEETDQADDVS--IAASETSTKESFFTRYXXXXXXXXX 1199
L +R+ K + D +G+E+D + S ++ SE S K S
Sbjct: 1138 LLVVRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYS-----------HSN 1186
Query: 1200 XXXXRKTAKNKRRQERKRARGKKGTIYEEEYLIQSIGRLIDRLYQTQPEAIKLIEGLLRR 1259
+++KN+R+ ERK+ K+G+ E+ L++++ ++ + E +++ L
Sbjct: 1187 SRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLF 1246
Query: 1260 NKREQAYQIQKNFMELIDLLKENVQEIYSIS 1290
EQ ++QK F + + L++ ++ EI++++
Sbjct: 1247 EFDEQGRELQKAFEDTLQLMERSLPEIWTLT 1277
>Hs4504629 [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1332
Score = 445 bits (1144), Expect = e-124
Identities = 358/1351 (26%), Positives = 606/1351 (44%), Gaps = 184/1351 (13%)
Query: 28 CFDTLSDSITCVLGAADIGALEVQ---QYMKDGSMNVLASFYVQSYNDKLLSFIHFDDIN 84
CF ++ T ++G+ + G +EV + +K+ V F + + +++ D
Sbjct: 23 CFSLRTEQGTVLIGS-EHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQE 81
Query: 85 ELVFVFQQGDIISVTYDPATMDYHSSKVSIVGSIDLGIEAAEWSADQETLAIVTFERNVV 144
+ GD+I + + ++ VGS+ GI WS DQE + + T ++ ++
Sbjct: 82 SVCVATASGDVILCSLS-------TQQLECVGSVASGISVMSWSPDQELVLLATGQQTLI 134
Query: 145 LLSRQLEPIVETSLQVEDLKISKHVTVGWGKKDTQFRGKGARAMEREALESLKASGLVGN 204
++++ EPI+E + +D SK +TVGWG+K+TQF G R +
Sbjct: 135 MMTKDFEPILEQQIHQDDFGESKFITVGWGRKETQFHGSEGRQAAFQM------------ 182
Query: 205 ELRDPTMPYRVDTGAITELDSRKVKISWRGDCEYFAVTTIETVKDPSDESKTVERRALRV 264
++ + +P+ D + +++WRGD ++FAV+ + R +RV
Sbjct: 183 QMHESALPW----------DDHRPQVTWRGDGQFFAVSVV---------CPETGARKVRV 223
Query: 265 FTRDGQLDSASEPVDGMNEHLSWKPQGSLIASVQRKTHIPDEEGLDLIFFERNGLRHGEF 324
+ R+ L S SEPV G+ L+WKP GSLIAS Q K P+++ D++FFE+NGL HG F
Sbjct: 224 WNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDK---PNQQ--DIVFFEKNGLLHGHF 278
Query: 325 DLRLPSDE-PVLDLCWNANSEILTIVLIDR-----------VQLWTTKNYHWFLKQEFYF 372
L DE V DL WNA+S +L + L D VQLWT NYHW+LKQ F
Sbjct: 279 TLPFLKDEVKVNDLLWNADSSVLAVRLEDLQREKSSIPKTCVQLWTVGNYHWYLKQSLSF 338
Query: 373 NNITYAK-----WHPEKDFTLMV-GDSEKMTIVDFAYKMTAGPTMQPFDNGTSIVIDGNV 426
+ +K W P + L V D+ + D VIDGN
Sbjct: 339 STCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNR 398
Query: 427 VNITPLGIANVPPPLYFRDFECPNNVLDAACSVSNEVYAAITKDELVIASVPSLKAMKNG 486
V +T VPPP+ P+ V V+ + + D V+ + + K G
Sbjct: 399 VLVTVFRQTVVPPPMCTYQLLFPHPVNQ----VTFLAHPQKSNDLAVLDASNQISVYKCG 454
Query: 487 KHPWIVSTFNKSSFGTAFDTLRQLAFINDNTVAILLDTDNLSRIALIDITDN----TNP- 541
P + D +L + + + L T +L + I +N NP
Sbjct: 455 DCP-------------SADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPL 501
Query: 542 --SLITIIETFDKVVLLRSQFDYNFVVFETR---------------------DGKITQLS 578
L+T IE + + S+F V+ DG I L
Sbjct: 502 KLGLLTWIEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLC 561
Query: 579 ADGQLSTITRFPQLVYDFRVKRVESATAANDWGDEQSKTVAF------------------ 620
+ + ++ F+ + A W + V F
Sbjct: 562 CNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECV 621
Query: 621 -GLTNTGKLFANEVQLTSAVTSIEITDSFLLFTTAQHNLQFIHLNTTDYKPL-ATVEDDT 678
GLT+ + F N++++ S +TS + D FLL TT H Q L +K L A + +
Sbjct: 622 LGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNH 681
Query: 679 ID--ERVRAVERGSILVNVIPSKAAVILQAARGNLETIYPRIMVLSGVRANIIAKNYKEA 736
+ E +R VERGS +V V+P ++LQ RGNLE ++ R +VL+ +R + +KEA
Sbjct: 682 VSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEA 741
Query: 737 FVTCRTHRINLDILYDYDPELFLNNLPHFITEIERVDYLDLFISSLLEDDVTKTKYRETL 796
F R RINL+ +YD++P++FL N+ FI +I+ V++++LF + L E+DVTKT Y
Sbjct: 742 FECMRKLRINLNPIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMY---- 797
Query: 797 NFDSSTAFDVAPPPPTEMQLYMKKKMFNPKTSKVNKVCQAILDVLLNTPNFRQKYLQSII 856
P P +Y+ + +P +K++ VC A+ V+ + KY SI+
Sbjct: 798 ------------PAPVTSSVYLSR---DPDGNKIDLVCDAMRAVMESIN--PHKYCLSIL 840
Query: 857 TAYACQNPPNLRDALQLIDTVESEEQKD-------STVTYLCFLQDVNVIYKVALSLYDI 909
T++ + P L LQ + ++ D + YL L DVN +Y +L YD
Sbjct: 841 TSHVKKTTPELEIVLQKVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDF 900
Query: 910 HLTLAVAQKSQMDPREYLPFLQSLLDAEPLRRKFMIDDYLQNYELAIEHLAAIDKVDNTV 969
L L VA+KSQ DP+EYLPFL +L E ++F ID YL+ YE AI HL+ K
Sbjct: 901 DLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLS---KCGPEY 957
Query: 970 SSEFIEYVEEHDLFKHALNIFKSEQDRQNIIYHVYAKSLSSQQQYGDAGIIHEMLGEWKE 1029
E + +++ +L+ AL ++ + I Y + L + Y AG++ G ++
Sbjct: 958 FPECLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEK 1017
Query: 1030 ALDAYTLGKKWNEAMSVV--LDHFPDKTEDIATELISSLTFEHRYVDASQLEIRFMKNIK 1087
AL A+ W +A+ V L+ D+ + L L + +++DA+ + ++ +
Sbjct: 1018 ALSAFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYE 1077
Query: 1088 AGMDLLCRAYDYEAASLIAIAEHKSELIEEIVDPALGDGFGTIAELLADCKGQVNSQLKR 1147
+ LL +E A + ++ ++IE V P++ + L + KR
Sbjct: 1078 EAVLLLLEGAAWEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKR 1137
Query: 1148 LRELRQKKAE------DPFAFYGEETDQADDVS--IAASETSTKESFFTRYXXXXXXXXX 1199
L +R+ K + D +G+E+D + S ++ SE S K S
Sbjct: 1138 LLVVRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYS-----------HSN 1186
Query: 1200 XXXXRKTAKNKRRQERKRARGKKGTIYEEEYLIQSIGRLIDRLYQTQPEAIKLIEGLLRR 1259
+++KN+R+ ERK+ K+G+ E+ L++++ ++ + E +++ L
Sbjct: 1187 SRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLF 1246
Query: 1260 NKREQAYQIQKNFMELIDLLKENVQEIYSIS 1290
EQ ++QK F + + L++ ++ EI++++
Sbjct: 1247 EFDEQGRELQKAFEDTLQLMERSLPEIWTLT 1277
>7299482 [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1213
Score = 216 bits (551), Expect = 1e-55
Identities = 184/670 (27%), Positives = 317/670 (46%), Gaps = 45/670 (6%)
Query: 625 TGKLFANEVQLTSAVTSIEITDSFLLFTTAQHNLQFIHLNTTDYKPLATVEDDTIDERVR 684
TG L Q + I + F + L + LN + L DD R
Sbjct: 530 TGALVTLRNQHLLHIDGYRIGEDVTSFCVVTNYLVYTQLNAMHFVQL----DDRRQVASR 585
Query: 685 AVERGSILVNVIPSKAAVILQAARGNLETIYPRIMVLSGVRANIIAKNYKEAFVTCRTHR 744
+ERG+ +V + KA V+LQ RGNLE I PR++VL V + Y++A R R
Sbjct: 586 NIERGAKIVTAVARKARVVLQLPRGNLEAICPRVLVLELVGDLLERGKYQKAIEMSRKQR 645
Query: 745 INLDILYDYDPELFLNNLPHFITEIERVDYLDLFISSLLEDDVTKTKYRETLNFDSSTAF 804
INL+I++D+D + F++++ F+ +I +L LF+S L +D TK Y + N+D+S
Sbjct: 646 INLNIIFDHDVKRFVSSVGAFLNDINEPQWLCLFLSELQNEDFTKGMY--SSNYDAS--- 700
Query: 805 DVAPPPPTEMQLYMKKKMFNPKTSKVNKVCQAILDVLLNTPNFRQKYLQSIITAYACQNP 864
P++ ++ KV VC+ +L+ +N F ++ +ITAY
Sbjct: 701 --KQTYPSDYRV----------DQKVEYVCR-LLEQQMN--RFVSRFRLPLITAYV--KL 743
Query: 865 PNLRDALQLIDTVESEEQK--DSTVTYLCFLQDVNVIYKVALSLYDIHLTLAVAQKSQMD 922
L ALQ+I + E+ D + +L +L DVN +Y VAL YD L L VAQKSQ D
Sbjct: 744 GCLEMALQVIWKEQQEDASLADQLLQHLLYLVDVNDLYNVALGTYDFGLVLFVAQKSQKD 803
Query: 923 PREYLPFLQSLLDAEPLRRKFMIDDYLQNYELAIEHLAAIDKVDNTVSSEFIEYVEEHDL 982
P+E+LP+L L RKF IDD+L+ Y A+ HLAA + E +EY+ +H L
Sbjct: 804 PKEFLPYLNDLKALPIDYRKFRIDDHLKRYTSALSHLAACGEQH---YEEALEYIRKHGL 860
Query: 983 FKHALNIFKSEQDRQNIIYHVYAKSLSSQQQYGDAGIIHEMLGEWKEALDAYTLGKKWNE 1042
+ L ++ + Q IY YA L + + +A +++E G+ ++AL + W
Sbjct: 861 YTDGLAFYREHIEFQKNIYVAYADHLRAIAKLDNASLMYERGGQLQQALLSAKHTLDWQR 920
Query: 1043 AMSVVLDHFPDKTEDIATELISSLTFEHRYVDASQLEIRFMKNIKAGMDLLCRAYDYEAA 1102
+ V+ + + +A L+ L + R+++A +L ++ K D+L + Y A
Sbjct: 921 VL-VLAKKLSEPLDQVAQSLVGPLQQQGRHMEAYELVKEHCQDRKRQFDVLLEGHLYSRA 979
Query: 1103 SLIAIAEHKSELIEEIVDPALGDGFGTIAELLADCKGQVNSQLKRLRELRQKKAEDPFAF 1162
A E ++ E+I L G + L AD + ++ + +RL ++R+ +A+ +
Sbjct: 980 IYEAGLE-DDDVSEKIAPALLAYGVQLESSLQADLQLFLDYK-QRLLDIRRNQAKSGEGY 1037
Query: 1163 YGEETDQADDVSIAASETSTKESFFTRYXXXXXXXXXXXXXRKTAKNKRRQERKRARGKK 1222
+ + +V + + TS S ++ +++KN+R+ ERK K
Sbjct: 1038 IDTDVN-LKEVDLLSDTTSLHSSQYS------GTSRRTGKTFRSSKNRRKHERKLFSLKP 1090
Query: 1223 GTIYEEEYLIQSIGRLIDRLYQTQPEAIKLIEGLLR----RNKREQAYQIQKNFMELIDL 1278
G +E+ LI ++ + ++ Q Q + LL+ + A +Q+ F L+
Sbjct: 1091 GNPFEDIALIDALHNHVTKIAQQQQPVRDTCKALLQLANAADADPLAAALQREFKTLLQA 1150
Query: 1279 LKENVQEIYS 1288
+ + EI++
Sbjct: 1151 VDAALDEIWT 1160
Score = 134 bits (338), Expect = 7e-31
Identities = 111/340 (32%), Positives = 168/340 (48%), Gaps = 64/340 (18%)
Query: 119 DLGIEAAEWSADQETLAIVTFERNVVLLSRQLEPIVETSLQVEDLKISKHVTVGWGKKDT 178
D+GIE+ WS +QE +A VT NVVL++ + I E L E + V VGWGKK+T
Sbjct: 101 DVGIESMAWSPNQEVVAFVTRTHNVVLMTSTFDVIAEQPLDAELDPDQQFVNVGWGKKET 160
Query: 179 QFRG-KGARAMEREALESLKASGLVGNELRDPTMPYRVDTGAITELDSRKVKISWRGDCE 237
QF G +G +A +++ +S +RD EL ++ V ISWRGD E
Sbjct: 161 QFHGSEGKQAAKQKESDS--------TFIRDE-----------QEL-NQDVSISWRGDGE 200
Query: 238 YFAVTTIETVKDPSDESKTVERRALRVFTRDGQLDSASEPVDGMNEHLSWKPQGSLIASV 297
+F V+ + R +V+ +G+L+ +E + + + W+P G+ IA
Sbjct: 201 FFVVSYVAAQLG----------RTFKVYDSEGKLNHTAEKSANLKDSVVWRPTGNWIAVP 250
Query: 298 QRKTHIPDEEGLDLIFFERNGLRHGE----FDLRLPSDEPVLDLCWNANSEILTIVLI-- 351
Q+ P++ + L FE+NGLRH E FDL+ +EPV+ L W+ +S+IL I
Sbjct: 251 QQ---FPNKSTIAL--FEKNGLRHRELVLPFDLQ---EEPVVQLRWSEDSDILAIRTCAK 302
Query: 352 --DRVQLWTTKNYHWFLKQEFYFNN---ITYAKWHPE--KDFTL-MVGDSEKMTIVDFAY 403
RV L+T NYHW+LKQ F + W + TL ++ +S K + +A+
Sbjct: 303 EEQRVYLYTIGNYHWYLKQVLIFEQADPLALLHWDTRCGAEHTLHVLKESGKHLVYRWAF 362
Query: 404 KMTAGPTMQPFDNGTSI--VIDGNVVNITPLGIANVPPPL 441
+ D SI VIDG + +T A VPPP+
Sbjct: 363 AV---------DRNNSIVGVIDGKRLLLTDFDEAIVPPPM 393
>CE28103 [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1250
Score = 170 bits (431), Expect = 1e-41
Identities = 273/1291 (21%), Positives = 505/1291 (38%), Gaps = 228/1291 (17%)
Query: 73 KLLSFIHFDDINELVFVFQQGDIISVTYDPATMDYHSSKVSIVGSIDLGIEAAEWSADQE 132
+++S D N++V + G + V D MD ++++ D + AAEW+AD++
Sbjct: 62 EVISLSFRTDGNQIVVILADGRALIVE-DGEVMDLEIAELT-----DTTVSAAEWTADEQ 115
Query: 133 TLAIVTFERNVVLLSRQLEPIVETSLQV-EDLKISKHVTVGWGKKDTQFRGKGARAMERE 191
TLA+ + + L L P E L E+ + S V VGWG + TQFRG + E
Sbjct: 116 TLALAD-NQTLYLADSSLVPFAERPLIFSENERKSAPVNVGWGSESTQFRGSAGKLKPGE 174
Query: 192 ALESLKASGLVGNELRDPTMPYRVDTGAITELDSRKVKISWRGDCEYFAVTTIETVKDPS 251
+E K E SRK + WR D E AV+ + D
Sbjct: 175 KIEKEKEQ---------------------IEQHSRKTSVHWRWDGEIVAVSFYSSQND-- 211
Query: 252 DESKTVERRALRVFTRDGQ-LDSASEPVDGMNEHLSWKPQGSLIASVQRKTHIPDEEGLD 310
R L VF R+G+ L++ + ++ + KP +L+ S ++ D
Sbjct: 212 -------TRNLTVFDRNGEILNNMNIRNIYLSHCFAHKPNANLLCSAIQENGSDDR---- 260
Query: 311 LIFFERNGLRHGEFDLRLPS----DEPVLD-LCWNANSEILTIVLI----DRVQLWTTKN 361
++ +ERNG + ++ P+ D +++ + WN+ IL++ +++ W N
Sbjct: 261 IVIYERNGETRNSYVVKWPANQIEDRRIIEKIEWNSTGTILSMQTSLGKKHQLEFWHLSN 320
Query: 362 YHWFLKQEFYFNNITYAKWHPEKDFTLMVGDSEKMTIVDFAYKMTAGPTMQPFD-NGTSI 420
Y + K + F+ KW T+ + E + + + PT D ++
Sbjct: 321 YEFTRKCYWKFSESIIWKWS-----TVECQNIEVLLESGQFFSVHITPTASFSDVISQNV 375
Query: 421 VIDGNVVNITPLGIANVPPPLYFRDFECPNNVLDAACSVSNEVYAAITKDELVIASVPSL 480
V+ + + + L VPPP+ +C ++++ A + S IT D +I+ +
Sbjct: 376 VVATDELRMYSLCRRVVPPPMCDYSIQCLSDIV--AYTTSTHHVHVITSDWKIISCMLFF 433
Query: 481 KAMKNG------KHPWIVSTFNKSSFGTAFDTLRQLAFINDNTVAILLDTD----NLSRI 530
K K + +I+ S T F A+ DTD N R
Sbjct: 434 KKKKRNYSNPFFRKKYILEILKVPSHKTYFACF-----------AVSQDTDGYKFNSDRA 482
Query: 531 ALIDITDNTNPSLITIIETFDKVVLLRSQFDYNFVVFETRDGKITQLSADGQLSTITRFP 590
++ ++ I +D+ +++++ GK Q+S + P
Sbjct: 483 SIDEVLHTEVTEGIICGFVYDEP-------SESYIIWNVSHGK-------HQISRVGANP 528
Query: 591 QLVYDFR----------VKRVESATAANDWGDEQSKTVAFGL------------------ 622
+ +++ K VE A+ + D +K F +
Sbjct: 529 EKIFEGENIGWIGVNPSNKHVEIASNDGKFIDLNTKEELFKIDKFESTEVHFIQNHHVIQ 588
Query: 623 TNTGKLFANEVQLTSAVTSIEITDSFLLFTTAQHNLQFIHLNTTDYKPLATVEDDTIDER 682
+ LF + +++ SI S +L + L+FI D + T+ED
Sbjct: 589 VDNSMLFLDSERVSQDAISILTRGSDILLIDFDNKLRFI-----DAESGKTLED------ 637
Query: 683 VRAVERGSILVNVIPSKAAVILQAARGNLETIYPRIMVLSGVRANIIAKNYKEAFVTCRT 742
VR VE G LV A VILQAARGNLETI PR V++ R + K Y +F +
Sbjct: 638 VRNVEAGCELVACDSQSANVILQAARGNLETIQPRRYVMAHTRDLLDRKEYIASFKWMKK 697
Query: 743 HRINLDILYDYDPELFLNNLPHFITEIERVDYLDLFISSLLE--DDVTKTKYRETLNFDS 800
HR+++ Y + +++P ++ +L+ + S E +D + +
Sbjct: 698 HRVDMSFAMKYKGDDLEDDIPIWLKTSNDSQFLEQLLISCTEVFEDAGSSLCMTVARY-- 755
Query: 801 STAFDVAPPPPTEMQLYMKKKMFNPKTSKVNKVCQAILDVLLNTPNFRQKYLQSIITAYA 860
D++ T+M + + K SKVN + + Q++++ I
Sbjct: 756 --VRDLSDAEKTKMFPLLLTALLRSKPSKVNDCLKEV-----------QEHVEKI----- 797
Query: 861 CQNPPNLRDALQLIDTVESEEQKD----STVTYLCFLQDVNVIYKVALSLYDIHLTLAVA 916
++KD +++ ++ F ++ ALS YD+ L VA
Sbjct: 798 -------------------ADRKDVFTRNSLHHISFFVPAKELFNCALSTYDLKLAQQVA 838
Query: 917 QKSQMDPREYLPFLQSLLDAE-PLRRKFMIDDYLQNYELAIEHLAAIDK-----VDNTVS 970
+ S DP+EYLP L L L R++ I+ + + A+ L +D + T
Sbjct: 839 EASNYDPKEYLPVLNKLNRVMCTLERQYRINVVREAWIDAVSSLFLLDSSKERGSEETWW 898
Query: 971 SEFIEYVEEHDLFKHALNIFKSEQDRQNIIYHVYAKSLSSQQQYGDAGIIHEMLGEWKEA 1030
++ + ++ L++ AL + K R +YA L + + +A + +E+ G ++
Sbjct: 899 NDIEDIIQREKLYQDALTLVKPGDRRYKQCCELYAAELERKVHWREAALFYELSGNSEKT 958
Query: 1031 LDAYTLGKKWNEAMSVVLDHFPDKTEDIATELISSLTFEHRYVDASQLEIRFMKNIKAGM 1090
L K W MS +D +A + L + + E R K + +
Sbjct: 959 L------KCWE--MSRDVDGLAASARRLAVD-AGKLKIHAIKMSTTLREARQPKELAKAL 1009
Query: 1091 DL-----------LCRAYDY-EAASLIAIAEHKSELIEEIVDPALGDGFGTIAELLADCK 1138
L LC A+++ +A+ + + + EE + A + L K
Sbjct: 1010 KLAGSSSTQIVHVLCDAFEWLDASREVEVGK------EEALKKAALSRNDQVLMDLERRK 1063
Query: 1139 GQVNSQLKRLRELRQKKAE--DPFAFYGEETDQADDVSIAASETSTKESFFTRYXXXXXX 1196
+ + KRL +R+ K + + FA GE D DD+S+ +S +S S
Sbjct: 1064 TEFENYKKRLAVVRENKLKRVEQFA-AGEVDDLRDDISVISSISSRSGS----------- 1111
Query: 1197 XXXXXXXRKTAKNKRRQERKRARGKKGTIYEEEYLIQSIGRLIDRLYQTQPEAIKLIEGL 1256
T + +++ E+K++ K+G YE+ L+ + L E +LI L
Sbjct: 1112 --SKVSMASTVRRRKQIEKKKSSLKEGGEYEDSALLNVLSENYRWLENIGNELSQLILVL 1169
Query: 1257 LRRNKREQAYQIQKNFMELIDLLKENVQEIY 1287
+ ++ +++ + E L+++ I+
Sbjct: 1170 ITVGNFPESLKLRSAYDEFATKLQKSKAAIW 1200
>At5g13680 [K] KOG1920 IkappaB kinase complex IKAP component
Length = 1319
Score = 164 bits (416), Expect = 7e-40
Identities = 147/580 (25%), Positives = 265/580 (45%), Gaps = 60/580 (10%)
Query: 687 ERGSILVNVIPS-KAAVILQAARGNLETIYPRIMVLSGVRANIIAKNYKEAFVTCRTHRI 745
ERG+ ++ V+ +AAVILQ RGNLE IYPR +VLS + + + +K+AF R HRI
Sbjct: 676 ERGAKVIGVLNGDEAAVILQTMRGNLECIYPRKLVLSSITNALAQQRFKDAFNLVRRHRI 735
Query: 746 NLDILYD-YDPELFLNNLPHFITEIERVDYLDLFISSLLEDDVTKTKYRETLNFDSSTAF 804
+ +++ D Y + FL + F+ ++ ++++ F+ ++ +DVT+T Y++ F S
Sbjct: 736 DFNVIVDLYGWQAFLQSAVAFVEQVNNLNHVTEFVCAMKNEDVTETLYKK---FSFSKKG 792
Query: 805 DVAPPPPTEMQLYMKKKMFNPKTS---KVNKVCQAILDVLL-NTPNFRQKYLQSIITAYA 860
D ++F K S KV+ V QAI L + P + L I+T A
Sbjct: 793 D---------------EVFRVKDSCSNKVSSVLQAIRKALEEHIPESPSREL-CILTTLA 836
Query: 861 CQNPPNLRDALQLIDTVESEEQKDST--------------VTYLCFLQDVNVIYKVALSL 906
+PP + ++L I +V E +S+ + +L +L D +++ AL L
Sbjct: 837 RSDPPAIEESLLRIKSVREMELLNSSDDIRKKSCPSAEEALKHLLWLLDSEAVFEAALGL 896
Query: 907 YDIHLTLAVAQKSQMDPREYLPFLQSLLDAEPLRRKFMIDDYLQNYELAIEHLAAIDKVD 966
YD++L VA SQ DP+E+LP+LQ L F ID LQ ++ A+
Sbjct: 897 YDLNLAAIVALNSQRDPKEFLPYLQELEKMPESLMHFKIDIKLQRFDSALR--------- 947
Query: 967 NTVSSEFIEYVEEHDLFKHALNIFK------SEQDRQNIIYHVYAKSLSSQQQYGDAGII 1020
N VS+ + + +L K +F ++ +++ ++ +A L ++++ DA
Sbjct: 948 NIVSAGVGYFPDCMNLIKKNPQLFPLGLLLITDPEKKLVVLEAWADHLIDEKRFEDAATT 1007
Query: 1021 HEMLGEWKEALDAYTLGKKWNEAMSV--VLDHFPDKTEDIATELISSLTFEHRYVDASQL 1078
+ + ++A AY W+ + V ++ D+ +A EL + + +A+++
Sbjct: 1008 YLCCCKLEKASKAYRECGDWSGVLRVGALMKLGKDEILKLAYELCEEVNALGKPAEAAKI 1067
Query: 1079 EIRFMKNIKAGMDLLCRAYDYEAASLIAIAEHKSELIEEIVDPALGDGFGTIAELLADCK 1138
+ + +I G+ LL A ++E A +A + I + AL G ++E +
Sbjct: 1068 ALEYCSDISGGISLLINAREWEEALRVAFLHTADDRISVVKSSALECASGLVSEFKESIE 1127
Query: 1139 GQVNSQLKRLRELRQKKAEDPFAFYGEETDQADDVSIAASETSTKESFFTRYXXXXXXXX 1198
+V L R +RQ++ EE D ASE S+ S + Y
Sbjct: 1128 -KVGKYLTRYLAVRQRRLLLAAKLKSEERSVVDLDDDTASEASSNLSGMSAYTLGTRRGS 1186
Query: 1199 XXXXXRKTAKNKR---RQERKRARGKKGTIYEEEYLIQSI 1235
A ++ R++RK + + G+ EE L+ +
Sbjct: 1187 AASVSSSNATSRARDLRRQRKSGKIRAGSAGEEMALVDHL 1226
Score = 102 bits (254), Expect = 4e-21
Identities = 74/238 (31%), Positives = 114/238 (47%), Gaps = 23/238 (9%)
Query: 228 VKISWRGDCEYFAVTTIETVKDPSDESKTVERRALRVFTRD-GQLDSASEPVDGMNEHLS 286
+ ISWRGD +YFA T+ V + SK + +++ D G L S+SE + L
Sbjct: 177 ISISWRGDGKYFA--TMGEVYESGCMSKKI-----KIWESDSGALQSSSETKEFTQGILE 229
Query: 287 WKPQGSLIASVQRKTHIPDEEGLDLIFFERNGLRHGEFDLRLPSD--EPVLDLCWNANSE 344
W P G+ IA+V ++ D+ + FFERNGL F + P D E +L WN+ S+
Sbjct: 230 WMPSGAKIAAVYKRKS--DDSSPSIAFFERNGLERSSFRIGEPEDATESCENLKWNSASD 287
Query: 345 ILTIVL----IDRVQLWTTKNYHWFLKQEFYFNNIT--YAKWHPEKDFTLMVGDSEKMTI 398
+L V+ D +++W N HW+LKQE + W P K L+
Sbjct: 288 LLAGVVSCKTYDAIRVWFFSNNHWYLKQEIRYPREAGVTVMWDPTKPLQLICWTLSGQVS 347
Query: 399 VDFAYKMTAGPTMQPFDNGTSIVIDGNVVNITPLGIANVPPPLYFRDFECPNNVLDAA 456
V +TA ++ T+ VID + + +TPL ++ +PPP+Y + V D A
Sbjct: 348 VRHFMWVTA-----VMEDSTAFVIDNSKILVTPLSLSLMPPPMYLFSLSFSSAVRDIA 400
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,188,921
Number of Sequences: 60738
Number of extensions: 3258153
Number of successful extensions: 9626
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 9548
Number of HSP's gapped (non-prelim): 15
length of query: 1325
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1207
effective length of database: 23,222,132
effective search space: 28029113324
effective search space used: 28029113324
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)