ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1379 good M KOG1322 Cell wall/membrane/envelope biogenesis GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1379 489966 488884 -361
(361 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL055c [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phos... 661 0.0
SPCC1906.01 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-... 530 e-150
7296813 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phos... 454 e-127
At2g39770 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-ph... 445 e-125
Hs11761621 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-p... 428 e-120
At3g55590 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-ph... 417 e-116
CE16911 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phos... 416 e-116
Hs11761619 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-p... 413 e-115
At4g30570 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-ph... 365 e-101
ECU11g0690 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-p... 296 2e-80
At1g74910 [GMO] KOG1460 GDP-mannose pyrophosphorylase 217 2e-56
CE22073 [GMO] KOG1460 GDP-mannose pyrophosphorylase 203 3e-52
CE24353 [GMO] KOG1460 GDP-mannose pyrophosphorylase 196 6e-50
Hs11761617 [GMO] KOG1460 GDP-mannose pyrophosphorylase 193 3e-49
At2g04650 [GMO] KOG1460 GDP-mannose pyrophosphorylase 191 1e-48
7303047 [GMO] KOG1460 GDP-mannose pyrophosphorylase 172 5e-43
SPBC13G1.02 [GMO] KOG1460 GDP-mannose pyrophosphorylase 163 3e-40
Hs14734024 [GMO] KOG1460 GDP-mannose pyrophosphorylase 114 3e-25
SPAC8C9.15c [J] KOG1461 Translation initiation factor 2B epsilon... 60 6e-09
Hs9966779 [J] KOG1462 Translation initiation factor 2B gamma sub... 55 2e-07
CE23548 [J] KOG1462 Translation initiation factor 2B gamma subun... 55 2e-07
>YDL055c [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 361
Score = 661 bits (1706), Expect = 0.0
Identities = 329/361 (91%), Positives = 344/361 (95%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALA AGVTDIVLAVNYRPEVM
Sbjct: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVM 60
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKEL 120
VETLKKYE E+GV+ITFSVETEPLGTAGPLKLAE VLKKDNSPFFVLNSDVIC+YPFKEL
Sbjct: 61 VETLKKYEKEYGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEYPFKEL 120
Query: 121 ADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILN 180
ADFH+AHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKP EFVGNRINAGLYILN
Sbjct: 121 ADFHKAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPKEFVGNRINAGLYILN 180
Query: 181 PEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKR 240
PEVIDLI++KPTSIEKETFPILVE+K LYSFDLEG+WMDVGQPKDFLSGTVLYLNSL+KR
Sbjct: 181 PEVIDLIEMKPTSIEKETFPILVEEKQLYSFDLEGFWMDVGQPKDFLSGTVLYLNSLAKR 240
Query: 241 DPAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKD 300
P KLA G NIVGN L+DPTAKIS TAK+GPDVVIGPNV IGDGVRITRSV L NS IK+
Sbjct: 241 QPKKLATGANIVGNALIDPTAKISSTAKIGPDVVIGPNVTIGDGVRITRSVVLCNSTIKN 300
Query: 301 HALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAII 360
H+LVKSTI+GWNSTVG+W RLEGVTVLGDDVEVKDEIYINGGKVLPHKSIS NVPKEAII
Sbjct: 301 HSLVKSTIVGWNSTVGQWCRLEGVTVLGDDVEVKDEIYINGGKVLPHKSISDNVPKEAII 360
Query: 361 M 361
M
Sbjct: 361 M 361
>SPCC1906.01 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 363
Score = 530 bits (1365), Expect = e-150
Identities = 255/355 (71%), Positives = 299/355 (83%), Gaps = 1/355 (0%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
MK LILVGG+GTRLRPLTLT+PKPLVEFGN+PMILHQ+EALAAAGVTDIVLAVNYRPE+M
Sbjct: 1 MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQVEALAAAGVTDIVLAVNYRPEIM 60
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKEL 120
VE LKKYE E+ V+ITFSVE EPLGTAGPL LA +L KD+SPFFVLNSDVIC+YPF +L
Sbjct: 61 VEALKKYEKEYNVNITFSVENEPLGTAGPLALARDILAKDHSPFFVLNSDVICEYPFADL 120
Query: 121 ADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILN 180
A FH+AHG +GTIV TKV+EPSKYGV+VH + +LI+RFVEKPVEFV NRIN G+YILN
Sbjct: 121 AAFHKAHGAEGTIVVTKVEEPSKYGVVVHYPNSESLIERFVEKPVEFVSNRINGGIYILN 180
Query: 181 PEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKR 240
P V+D I+ +PTSIEKE FP +V K L+SFDLEGYWMDVGQPKD+L+GT LYL+SL K
Sbjct: 181 PSVLDRIEPRPTSIEKEVFPAMVNDKQLHSFDLEGYWMDVGQPKDYLTGTCLYLSSLRKH 240
Query: 241 DPAKLA-KGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIK 299
P LA NI+GNVL+DP+A I K+GP+VVIGPNV IGDGVR+ R L +S ++
Sbjct: 241 KPEILAPASSNIIGNVLIDPSATIGKNCKIGPNVVIGPNVTIGDGVRLQRCAILKSSRVR 300
Query: 300 DHALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNV 354
DHA VKS+I+GWNST+G W+RLE V+VLGDDV V DEIY+NGG +LPHKSIS N+
Sbjct: 301 DHAWVKSSIVGWNSTLGSWSRLENVSVLGDDVVVNDEIYVNGGSILPHKSISANI 355
>7296813 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 369
Score = 454 bits (1167), Expect = e-127
Identities = 218/360 (60%), Positives = 277/360 (76%), Gaps = 2/360 (0%)
Query: 2 KGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVMV 61
+ LILVGGYGTRLRPLTL+ PKPLVEF N+P++LHQ+EAL AG ++LAV+YR E M
Sbjct: 12 RALILVGGYGTRLRPLTLSTPKPLVEFANKPILLHQLEALVDAGCRQVILAVSYRAEQME 71
Query: 62 ETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKELA 121
+ LK + GV + FS ETEPLGTAGPL LA+++L + PFFVLNSDVICD+PFK+L
Sbjct: 72 KELKVEAKKLGVELIFSHETEPLGTAGPLALAKTILAASSEPFFVLNSDVICDFPFKQLV 131
Query: 122 DFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILNP 181
FH HG +GTIV TKV+EPSKYGV+++D I F+EKP EFV N+INAG+YI NP
Sbjct: 132 QFHCNHGKEGTIVVTKVEEPSKYGVVLYD--ENGCIKNFIEKPQEFVSNKINAGIYIFNP 189
Query: 182 EVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKRD 241
V+D I++KPTSIEKE FP + +Q+ LY+ DL G+WMD+GQPKDFL+G LYL+SL ++
Sbjct: 190 SVLDRIEVKPTSIEKEVFPEMTQQQELYAMDLTGFWMDIGQPKDFLTGMCLYLSSLRQKQ 249
Query: 242 PAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDH 301
KL G +VGNVLVDPTAKI ++GP+V IGP+VVI DGV I RS L + ++ H
Sbjct: 250 SPKLYTGPGVVGNVLVDPTAKIGEGCRIGPNVTIGPDVVIEDGVCIKRSTILKGAIVRSH 309
Query: 302 ALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAIIM 361
+ + S I+GW STVG+W R+EG+TVLG+DV VKDE+YINGG+VLPHKSI+ +VP+ IIM
Sbjct: 310 SWLDSCIVGWRSTVGRWVRIEGITVLGEDVIVKDELYINGGQVLPHKSIAASVPEPQIIM 369
>At2g39770 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 361
Score = 445 bits (1144), Expect = e-125
Identities = 214/362 (59%), Positives = 277/362 (76%), Gaps = 2/362 (0%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
MK LILVGG+GTRLRPLTL+ PKPLV+F N+PMILHQIEAL A GV ++VLA+NY+PEVM
Sbjct: 1 MKALILVGGFGTRLRPLTLSFPKPLVDFANKPMILHQIEALKAVGVDEVVLAINYQPEVM 60
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLA-ESVLKKDNSPFFVLNSDVICDYPFKE 119
+ LK +E + + IT S ETEPLGTAGPL LA + +L PFFVLNSDVI +YP KE
Sbjct: 61 LNFLKDFETKLEIKITCSQETEPLGTAGPLALARDKLLDGSGEPFFVLNSDVISEYPLKE 120
Query: 120 LADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYIL 179
+ +FH++HGG+ +I+ TKVDEPSKYGV+V + +T +++FVEKP +VGN+INAG+Y+L
Sbjct: 121 MLEFHKSHGGEASIMVTKVDEPSKYGVVVMEESTGR-VEKFVEKPKLYVGNKINAGIYLL 179
Query: 180 NPEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSK 239
NP V+D I+L+PTSIEKETFP + + LY+ L G+WMD+GQP+D+++G LYL+SL K
Sbjct: 180 NPSVLDKIELRPTSIEKETFPKIAAAQGLYAMVLPGFWMDIGQPRDYITGLRLYLDSLRK 239
Query: 240 RDPAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIK 299
+ PAKL G +IVGNVLVD TA I +GPDV IGP ++ GVR++R + IK
Sbjct: 240 KSPAKLTSGPHIVGNVLVDETATIGEGCLIGPDVAIGPGCIVESGVRLSRCTVMRGVRIK 299
Query: 300 DHALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAI 359
HA + S+IIGW+STVG+WAR+E +T+LG+DV V DEIY NGG VLPHK I N+ K I
Sbjct: 300 KHACISSSIIGWHSTVGQWARIENMTILGEDVHVSDEIYSNGGVVLPHKEIKSNILKPEI 359
Query: 360 IM 361
+M
Sbjct: 360 VM 361
>Hs11761621 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 360
Score = 428 bits (1100), Expect = e-120
Identities = 205/361 (56%), Positives = 270/361 (74%), Gaps = 1/361 (0%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
MK LILVGGYGTRLRPLTL+ PKPLV+F N+P++LHQ+EALAAAGV ++LAV+Y +V+
Sbjct: 1 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKEL 120
+ +K E G+ I+ S E EPLGTAGPL LA +L + PFFVLNSDVICD+PF+ +
Sbjct: 61 EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAM 120
Query: 121 ADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILN 180
FH+ HG +G+I+ TKV+EPSKYGV+V + T I RFVEKP FV N+INAG+YIL+
Sbjct: 121 VQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGR-IHRFVEKPQVFVSNKINAGMYILS 179
Query: 181 PEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKR 240
P V+ I L+PTSIEKE FPI+ ++ LY+ +L+G+WMD+GQPKDFL+G L+L SL ++
Sbjct: 180 PAVLRRIQLQPTSIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQK 239
Query: 241 DPAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKD 300
P +L G IVGNVLVDP+A+I +GP+V +GP VV+ DGV I R L ++ I+
Sbjct: 240 QPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRS 299
Query: 301 HALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAII 360
H+ ++S I+GW VG+W R+E VTVLG+DV V DE+Y+NG VLPHKSI +VP+ II
Sbjct: 300 HSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRII 359
Query: 361 M 361
M
Sbjct: 360 M 360
>At3g55590 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 364
Score = 417 bits (1072), Expect = e-116
Identities = 208/365 (56%), Positives = 272/365 (73%), Gaps = 5/365 (1%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPE-- 58
MK LILVGG+GTRLRPLTL++PKPLV+F N+PMILHQIEAL A GV ++VLA+NY PE
Sbjct: 1 MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQL 60
Query: 59 -VMVETLKKYEDEFGVSITFSVETEPLGTAGPLKLA-ESVLKKDNSPFFVLNSDVICDYP 116
VM + E G+ IT S ETEPLGTAGPL LA + ++ PFFVLNSDVI DYP
Sbjct: 61 LVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYP 120
Query: 117 FKELADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGL 176
+E+ FH AHGG+ +I+ TKVDEPSKYGV+V + AT ++RFVEKP FVGN+INAG+
Sbjct: 121 LEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGR-VERFVEKPKLFVGNKINAGI 179
Query: 177 YILNPEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNS 236
Y+LNP V+D I+L+PTSIEKE FP + E + LY+ L G+WMD+GQP+D+++G LYL+S
Sbjct: 180 YLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDS 239
Query: 237 LSKRDPAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNS 296
L K+ P+KLA G +I+GNVLVD TA+I +GP+V IGP V+ GVR++ +
Sbjct: 240 LRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGV 299
Query: 297 HIKDHALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNVPK 356
H+K +A + S+IIGW+STVG+WAR+E +++LG +V V DEIY NGG VL +K I ++ K
Sbjct: 300 HVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILK 359
Query: 357 EAIIM 361
I+M
Sbjct: 360 PDIVM 364
>CE16911 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 373
Score = 416 bits (1069), Expect = e-116
Identities = 213/367 (58%), Positives = 263/367 (71%), Gaps = 8/367 (2%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
MK LILVGGYGTRLRPLTLT PKPLVEF N+PM+LHQ+EALA GV +VLAV+YR E +
Sbjct: 9 MKALILVGGYGTRLRPLTLTQPKPLVEFANKPMMLHQMEALAEVGVDTVVLAVSYRAEQL 68
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKEL 120
+ + + D GV + FS+E EPLGTAGPL LA L+ D +PFFVLNSDVICD+PFK++
Sbjct: 69 EQEMTVHADRLGVKLIFSLEEEPLGTAGPLALARKHLEGD-APFFVLNSDVICDFPFKQM 127
Query: 121 ADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILN 180
+FH+ HG +GTI TKV+EPSKYGV+V D ID FVEKP E+VGN+INAGLYI +
Sbjct: 128 VEFHKNHGKEGTIAVTKVEEPSKYGVVVFD-QDKGKIDDFVEKPQEYVGNKINAGLYIFS 186
Query: 181 PEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKR 240
+++D I LKPTSIEKE FP + +LY+F L G+WMDVGQPKDFL G L+LN
Sbjct: 187 SKILDRIPLKPTSIEKEIFPEMAFSGNLYAFVLPGFWMDVGQPKDFLKGMSLFLNHCHTT 246
Query: 241 DPAKLAKGEN------IVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALS 294
KL G N I GNV+VDP+A + +GPDVVIGP V I GVRI S LS
Sbjct: 247 KSDKLETGSNIHPTATIRGNVMVDPSATVGENCVIGPDVVIGPRVKIEGGVRILHSTILS 306
Query: 295 NSHIKDHALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLPHKSISVNV 354
+S I +++ V +I+G +G W R+E + V+GDDV VKDE+Y+NG VLPHKSI+VNV
Sbjct: 307 DSSIGNYSWVSGSIVGRKCHIGSWVRIENICVIGDDVVVKDELYLNGASVLPHKSIAVNV 366
Query: 355 PKEAIIM 361
P + IIM
Sbjct: 367 PSKDIIM 373
>Hs11761619 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 387
Score = 413 bits (1062), Expect = e-115
Identities = 205/388 (52%), Positives = 270/388 (68%), Gaps = 28/388 (7%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
MK LILVGGYGTRLRPLTL+ PKPLV+F N+P++LHQ+EALAAAGV ++LAV+Y +V+
Sbjct: 1 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL 60
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKEL 120
+ +K E G+ I+ S E EPLGTAGPL LA +L + PFFVLNSDVICD+PF+ +
Sbjct: 61 EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAM 120
Query: 121 ADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILN 180
FH+ HG +G+I+ TKV+EPSKYGV+V + A I RFVEKP FV N+INAG+YIL+
Sbjct: 121 VQFHRHHGQEGSILVTKVEEPSKYGVVVCE-ADTGRIHRFVEKPQVFVSNKINAGMYILS 179
Query: 181 PEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKR 240
P V+ I L+PTSIEKE FPI+ ++ LY+ +L+G+WMD+GQPKDFL+G L+L SL ++
Sbjct: 180 PAVLRRIQLQPTSIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQK 239
Query: 241 DPAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKD 300
P +L G IVGNVLVDP+A+I +GP+V +GP VV+ DGV I R L ++ I+
Sbjct: 240 QPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRS 299
Query: 301 HALVKSTIIGWNSTVGKW---------------------------ARLEGVTVLGDDVEV 333
H+ ++S I+GW VG+W R+E VTVLG+DV V
Sbjct: 300 HSWLESCIVGWRCRVGQWVSLWAGLGGERGGECACLPDKAYPLLEVRMENVTVLGEDVIV 359
Query: 334 KDEIYINGGKVLPHKSISVNVPKEAIIM 361
DE+Y+NG VLPHKSI +VP+ IIM
Sbjct: 360 NDELYLNGASVLPHKSIGESVPEPRIIM 387
>At4g30570 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 331
Score = 365 bits (936), Expect = e-101
Identities = 176/332 (53%), Positives = 244/332 (73%), Gaps = 3/332 (0%)
Query: 21 VPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYR-PEVMVETLKKYEDEFGVSITFSV 79
+PKPLV+FGN+PMILHQIEAL AGVT++VLA+N++ PEVM+ +K+YE + + ITFS
Sbjct: 1 MPKPLVDFGNKPMILHQIEALKGAGVTEVVLAINHQQPEVMLNFVKEYEKKLEIKITFSQ 60
Query: 80 ETEPLGTAGPLKLA-ESVLKKDNSPFFVLNSDVICDYPFKELADFHQAHGGKGTIVATKV 138
ETEPLGTAGPL LA + ++ + PFFVLNSDVIC+YP E+ +FH+ + + +I+ T+V
Sbjct: 61 ETEPLGTAGPLALARDKLVDESGQPFFVLNSDVICEYPLLEMIEFHKTNRAEASIMVTEV 120
Query: 139 DEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILNPEVIDLIDLKPTSIEKET 198
D+PSKYGV+V + T ++ FVEKP FVGN+INAG+Y+L+P V+D I+L+ TSIEKE
Sbjct: 121 DDPSKYGVVVTEEGTAR-VESFVEKPKHFVGNKINAGIYLLSPSVLDRIELRRTSIEKEI 179
Query: 199 FPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKRDPAKLAKGENIVGNVLVD 258
FP + +K LY+ L G+WMD+GQPKD+++G +YLNSL ++ P +LA G+NI+GNVLV
Sbjct: 180 FPKIASEKKLYAMVLPGFWMDIGQPKDYITGQRMYLNSLREKTPQELATGDNIIGNVLVH 239
Query: 259 PTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTVGKW 318
+A I +GPDVVIGP VI GVR+ + IK+HA + ++I+GW+STVG+W
Sbjct: 240 ESAVIGEGCLIGPDVVIGPGCVIDSGVRLFGCTVMRGVWIKEHACISNSIVGWDSTVGRW 299
Query: 319 ARLEGVTVLGDDVEVKDEIYINGGKVLPHKSI 350
AR+ +TVLG DV V D N G V+ + +
Sbjct: 300 ARVFNITVLGKDVNVADAEVYNSGVVIEEQGL 331
>ECU11g0690 [M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate
guanylyltransferase
Length = 345
Score = 296 bits (759), Expect = 2e-80
Identities = 156/346 (45%), Positives = 222/346 (64%), Gaps = 19/346 (5%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
+K +ILVGGYGTRLRPLT TVPKPLV F N+P++ HQIEAL G+ +I+LA+NY E +
Sbjct: 8 VKAVILVGGYGTRLRPLTYTVPKPLVPFANKPILRHQIEALVKVGIKEIILALNYYSEFI 67
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKEL 120
+ ++ Y +E G+SI +S E EPLGTAGPL LA+ L + FFVLNSD+ C +P E+
Sbjct: 68 IREVRDYSNELGISIVYSKEQEPLGTAGPLALAKKYL--EGHTFFVLNSDITCRFPLAEM 125
Query: 121 ADFHQAHGGKGTIVATKVDEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILN 180
FH +HG +GTI++T VD+PS+YG+I+ + +T +L+ F+EKP + V NR+NAG+YILN
Sbjct: 126 LSFHYSHGREGTILSTNVDDPSRYGIIITEEST-SLVRSFLEKPKDAVSNRVNAGIYILN 184
Query: 181 PEVIDLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKR 240
P V+D I+L+ SIE+E FP + E+ L FDL+G+WMD+GQP D++ G +YL
Sbjct: 185 PSVLDRIELRECSIEREIFPRMAEEHQLQVFDLKGFWMDIGQPADYIKGQGMYLRHCQ-- 242
Query: 241 DPAKLAKGENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKD 300
E + N L AK+ + +VVIG NV IG V I+ S N I D
Sbjct: 243 --------EAGIDNQL---DAKM---FSIEDNVVIGRNVRIGRNVTISNSAIFDNVEIGD 288
Query: 301 HALVKSTIIGWNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKVLP 346
+ +++ +I+GWN+ + A + VLG V+ ++ K LP
Sbjct: 289 NVVIRDSIVGWNTKIEDNATVSTCCVLGYATTVERFSTLSSVKTLP 334
>At1g74910 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 415
Score = 217 bits (553), Expect = 2e-56
Identities = 129/405 (31%), Positives = 215/405 (52%), Gaps = 49/405 (12%)
Query: 4 LILVGG--YGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAA-GVTDIVLAVNYRPEVM 60
+I+VGG GTR RPL+L +PKPL +PM+ H I A + I L Y
Sbjct: 12 VIMVGGPTKGTRFRPLSLNIPKPLFPIAGQPMVHHPISACKRIPNLAQIYLVGFYEEREF 71
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDN-SPFFVLNSDVICDYPFKE 119
+ +E V + + E +P G+AG L +++ +D+ S F+LN DV C +P +
Sbjct: 72 ALYVSAISNELKVPVRYLREDKPHGSAGGLYHFRNLIMEDSPSHIFLLNCDVCCSFPLPK 131
Query: 120 LADFHQAHGGKGTIVATKV--DEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLY 177
+ + H+ +GG GT++ KV + S++G +V D T L+ + EKP FV +RIN G+Y
Sbjct: 132 MLEAHRGYGGIGTLLVIKVSPESASQFGELVADPVTNELL-HYTEKPETFVSDRINCGVY 190
Query: 178 ILNPEVIDLID--------------------LKPTS--------IEKETFPILVEQKSLY 209
+ PE+ + I L+P + ++++ L +K LY
Sbjct: 191 VFTPEIFNAIGDVSTQRKDRATLKRVSSFEALQPATRIPTDFVRLDQDILSPLAGKKRLY 250
Query: 210 SFDLEGYWMDVGQPKDFLSGTVLYLNSLSKRDPAKLAKGEN-----IVGNVLVDPTAKIS 264
+++ +W + P L + LYL+ P LA G+ ++G+V + P+AK+
Sbjct: 251 TYETMDFWEQIKSPGMSLRCSGLYLSQFRLTSPQLLASGDGTRSAIVIGDVYIHPSAKVH 310
Query: 265 PTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTVGKWARLE-- 322
PTAK+GP+V I N +G GVR+ + L + I ++A+V + I+GW S++G+W+R++
Sbjct: 311 PTAKIGPNVSISANARVGPGVRLMSCIILDDVEIMENAVVTNAIVGWKSSIGRWSRVQAE 370
Query: 323 -------GVTVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAII 360
GVT+LGD V V+DE+ + VLP+K+++V+V E I+
Sbjct: 371 GVYNSKLGVTILGDSVAVEDEVVVTSSIVLPNKTLNVSVQDEIIL 415
>CE22073 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 401
Score = 203 bits (517), Expect = 3e-52
Identities = 130/400 (32%), Positives = 201/400 (49%), Gaps = 43/400 (10%)
Query: 2 KGLILVGG--YGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAA-AGVTDIVLAVNYRPE 58
K ++LVGG GTR RPL+L +PKPL P+I H I+ L +G+++I+L + +
Sbjct: 4 KAVVLVGGPQKGTRFRPLSLQLPKPLFPIAGVPLIEHHIDQLCQLSGLSEILLLGFFPSD 63
Query: 59 VMVETLKKYEDEFGVSITFSVETEPLGTAGPL-KLAESVLKKDNSPFFVLNSDVICDYPF 117
V + + + + + VSI + E PLGTAG L + +L D FV+N+DV D P
Sbjct: 64 VFTDFISRCQQTYRVSIKYLEEPNPLGTAGGLVSFKKQILAGDPDAVFVINADVCGDLPI 123
Query: 118 KELADFHQAHGGKGTIVATKV---DEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINA 174
+++ + G ++ T + +G +V D + + +V+KP FV I+
Sbjct: 124 EDMGAKLDSLSGSSMLMLTTEATRQQSINFGSVVTD--SEGRVIHYVDKPTTFVSTNISC 181
Query: 175 GLYILNPEVIDLIDLKPTS----IEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGT 230
G+Y++ EVI +DL +E + P L +LY+ +W L
Sbjct: 182 GVYLIKAEVIRQLDLPLNGDGIWLETDVLPQLASSGNLYALHTTRWWSQTKTAAAVLYAN 241
Query: 231 VLYLNSLSKRDPAKLAK-GENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITR 289
YL +R A+L K G I+G+V +DP+AK+ PTAK+GP+V IGP VIG GVRI
Sbjct: 242 RHYLRLYKRRYAARLCKNGAQIIGDVFIDPSAKVHPTAKIGPNVSIGPKSVIGKGVRIKE 301
Query: 290 SVALSNSHIKDHALVKSTIIGWNSTVGKWARLEGV------------------------- 324
S+ L + I+++A V ++IGW S VG WAR+EG+
Sbjct: 302 SIILPEAVIEENACVLQSVIGWRSVVGMWARIEGIPLEPNPNLPFAKMDNKPLFLPDGRL 361
Query: 325 ----TVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAII 360
T+LG DV V E I VLP+K ++ + + I+
Sbjct: 362 TPSLTILGSDVSVAPETIILNCVVLPYKELTCSYKNQIIL 401
>CE24353 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 394
Score = 196 bits (497), Expect = 6e-50
Identities = 124/388 (31%), Positives = 193/388 (48%), Gaps = 41/388 (10%)
Query: 12 TRLRPLTLTVPKPLVEFGNRPMILHQIEALAA-AGVTDIVLAVNYRPEVMVETLKKYEDE 70
TR RPL+L +PKPL P+I H I+ L +G+++I+L + +V + + + +
Sbjct: 9 TRFRPLSLQLPKPLFPIAGVPLIEHHIDQLCQLSGLSEILLLGFFPSDVFTDFISRCQQT 68
Query: 71 FGVSITFSVETEPLGTAGPL-KLAESVLKKDNSPFFVLNSDVICDYPFKELADFHQAHGG 129
+ VSI + E PLGTAG L + +L D FV+N+DV D P +++ + G
Sbjct: 69 YRVSIKYLEEPNPLGTAGGLVSFKKQILAGDPDAVFVINADVCGDLPIEDMGAKLDSLSG 128
Query: 130 KGTIVATKV---DEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLYILNPEVIDL 186
++ T + +G +V D + + +V+KP FV I+ G+Y++ EVI
Sbjct: 129 SSMLMLTTEATRQQSINFGSVVTD--SEGRVIHYVDKPTTFVSTNISCGVYLIKAEVIRQ 186
Query: 187 IDLKPTS----IEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKRDP 242
+DL +E + P L +LY+ +W L YL +R
Sbjct: 187 LDLPLNGDGIWLETDVLPQLASSGNLYALHTTRWWSQTKTAAAVLYANRHYLRLYKRRYA 246
Query: 243 AKLAK-GENIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDH 301
A+L K G I+G+V +DP+AK+ PTAK+GP+V IGP VIG GVRI S+ L + I+++
Sbjct: 247 ARLCKNGAQIIGDVFIDPSAKVHPTAKIGPNVSIGPKSVIGKGVRIKESIILPEAVIEEN 306
Query: 302 ALVKSTIIGWNSTVGKWARLEGV-----------------------------TVLGDDVE 332
A V ++IGW S VG WAR+EG+ T+LG DV
Sbjct: 307 ACVLQSVIGWRSVVGMWARIEGIPLEPNPNLPFAKMDNKPLFLPDGRLTPSLTILGSDVS 366
Query: 333 VKDEIYINGGKVLPHKSISVNVPKEAII 360
V E I VLP+K ++ + + I+
Sbjct: 367 VAPETIILNCVVLPYKELTCSYKNQIIL 394
>Hs11761617 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 399
Score = 193 bits (491), Expect = 3e-49
Identities = 122/354 (34%), Positives = 184/354 (51%), Gaps = 33/354 (9%)
Query: 1 MKGLILVGG--YGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAA-GVTDIVLAVNYRP 57
+K +IL+GG GTR RPL+ VPKPL PMI H IEA A G+ +I+L Y+P
Sbjct: 2 LKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQP 61
Query: 58 -EVMVETLKKYEDEFGVSITFSVETEPLGTAGPL-KLAESVLKKDNSPFFVLNSDVICDY 115
E + + L+ + EF + + + E PLGT G L + +L FFVLN+DV D+
Sbjct: 62 DEPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRDQILAGSPEAFFVLNADVCSDF 121
Query: 116 PFKELADFHQAHGGKGTIVATKVDEPSK--YGVIVHDIATPNLIDRFVEKPVEFVGNRIN 173
P + + H+ ++ T + YG IV + T ++ +VEKP F+ + IN
Sbjct: 122 PLSAMLEAHRRQRHPFLLLGTTANRTQSLNYGCIVENPQTHEVL-HYVEKPSTFISDIIN 180
Query: 174 AGLYILNPEVI-----------------DLIDLKPTS----IEKETFPILVEQKSLYSFD 212
G+Y+ +PE + D L P + +E++ F L Q +Y
Sbjct: 181 CGIYLFSPEALKPLRDVFQRNQQDGQLEDSPGLWPGAGTIRLEQDVFSALAGQGQIYVHL 240
Query: 213 LEGYWMDVGQPKDFLSGTVLYLNSLSKRDPAKLAK----GENIVGNVLVDPTAKISPTAK 268
+G W + L + LYL+ P +LAK G I GNV + PTAK++P+A
Sbjct: 241 TDGIWSQIKSAGSALYASRLYLSRYQDTHPERLAKHTPGGPWIRGNVYIHPTAKVAPSAV 300
Query: 269 VGPDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTVGKWARLE 322
+GP+V IG V +G+GVR+ S+ L + +++H V I+GW STVG+WAR+E
Sbjct: 301 LGPNVSIGKGVTVGEGVRLRESIVLHGATLQEHTCVLHCIVGWGSTVGRWARVE 354
>At2g04650 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 385
Score = 191 bits (485), Expect = 1e-48
Identities = 118/390 (30%), Positives = 205/390 (52%), Gaps = 46/390 (11%)
Query: 4 LILVGG--YGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAA-AGVTDIVLAVNYRPEVM 60
+I+VGG GTR RPL+ PKPL+ +PMI H I A + + I L Y
Sbjct: 9 VIMVGGPTKGTRFRPLSFNTPKPLIPLAGQPMIHHPISACKKISNLAQIFLIGFYEEREF 68
Query: 61 VETLKKYEDEFGVSITFSVETEPLGTAGPLK-LAESVLKKDNSPFFVLNSDVICDYPFKE 119
+ +E + + + E +P G+AG L + ++++ S F+LN DV C +P +
Sbjct: 69 ALYVSSISNELKIPVRYLKEDKPHGSAGALYYFRDRIMEEKPSHVFLLNCDVCCSFPLQG 128
Query: 120 LADFHQAHGGKGTIVATKV--DEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAGLY 177
+ D H+ +GG GT++ KV + S++G ++ D T L+ + EKP FV + IN G+Y
Sbjct: 129 ILDAHRRYGGIGTMLVIKVSAEAASQFGELIADPDTKELL-HYTEKPETFVSDLINCGVY 187
Query: 178 ILNPEVIDLID-----LKPTS----------------IEKETFPILVEQKSLYSFDLEGY 216
+ ++ + I+ ++ TS ++++ L +K LY+++ + +
Sbjct: 188 VFTSDIFNAIEEVYSQIRDTSSNYQSATRSVPADFVRLDQDILSPLAGKKQLYTYENKDF 247
Query: 217 WMDVGQPKDFLSGTVLYLNSLSKRDPAKLAKGEN------IVGNVLVDPTAKISPTAKVG 270
W + P L + LYL+ + P LA G+ I+G+V + P+ K+ PTAK+G
Sbjct: 248 WEQIKTPGKSLKCSALYLSQFRETSPHILASGDGTNRKPTIIGDVYIHPSVKLHPTAKIG 307
Query: 271 PDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTVGKWARLEGVTVLGDD 330
P+V I NV +G GVR+ + L + IK++A+V ++IIGW S++ G+
Sbjct: 308 PNVSISANVRVGPGVRLISCIILDDVEIKENAVVINSIIGWKSSI------------GEA 355
Query: 331 VEVKDEIYINGGKVLPHKSISVNVPKEAII 360
V V+DE+ + G VL +K+++V+V + I+
Sbjct: 356 VTVEDEVAVIGSIVLQNKTLNVSVQDDIIL 385
>7303047 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 448
Score = 172 bits (437), Expect = 5e-43
Identities = 128/437 (29%), Positives = 193/437 (43%), Gaps = 79/437 (18%)
Query: 1 MKGLILVGG--YGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPE 58
+K +IL+GG GTR RPL+L PKPL RP+I H IEA A +L + Y P+
Sbjct: 2 LKAVILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQ 61
Query: 59 VMVE----TLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNS-PFFVLNSDVIC 113
+E ++ ++I + E LGTAG + ++ N FFVLN DV
Sbjct: 62 TQMEGFVGDMQALYSSSNINIRYLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVCA 121
Query: 114 DYPFKELADFHQAHGGKG--TIVATKVDEPSK--YGVIVHDIATPNLIDRFVEKPVEFVG 169
D+P +EL DFH+ TI++T+ YG +V D ++ + +VEKP +V
Sbjct: 122 DFPLQELCDFHEKRPASALVTIMSTEATRQQSLHYGCLVFDRSS-GAVSHYVEKPSSYVS 180
Query: 170 NRINAGLYILNPEVIDLI--------------------------DLKPTSIEKETFPILV 203
IN G+Y+ + ++ ++ + E+E L
Sbjct: 181 TFINCGVYVCSMDIFTVLAQIFHSRGQEYSCQAFCNGNGNGNGREQGHIKWEQEVLTPLA 240
Query: 204 EQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKRDPAKLA-----KGEN-------I 251
L++ + +W + + YL K P +LA +GE +
Sbjct: 241 GTDKLFAMPVPNWWSQLKTAGSAIYANRHYLGLYKKTHPERLANVGIKRGEGDGSLICTV 300
Query: 252 VGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGW 311
+V V P+A + +A +GP+V IGP V IG GVRI S+ L + I DH LV +I+G
Sbjct: 301 HPDVYVHPSATVHHSAVLGPNVAIGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGR 360
Query: 312 NSTVGKWARLEG-----------------------------VTVLGDDVEVKDEIYINGG 342
ST+G WAR+EG +T+LG V+V E +
Sbjct: 361 GSTIGAWARVEGTPSDPDPNKPFAKMENPPLFNNEGKLNPSITILGCFVQVPAEKILLNS 420
Query: 343 KVLPHKSISVNVPKEAI 359
VLPHK +S + E I
Sbjct: 421 IVLPHKELSRSFKNEII 437
>SPBC13G1.02 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 414
Score = 163 bits (413), Expect = 3e-40
Identities = 121/410 (29%), Positives = 193/410 (46%), Gaps = 54/410 (13%)
Query: 4 LILVGG--YGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAA-GVTDIVLAVNYRPEVM 60
+ILVGG GTR RPL+ VPKPL + G R MI H + AL+ V D+ L Y V
Sbjct: 6 VILVGGPSRGTRFRPLSFDVPKPLFKIGGREMIYHHLAALSKIESVKDVFLVGFYDESVF 65
Query: 61 VETLKKYEDEFGV--SITFSVETEPLGTAGPL-KLAESVLKKDNSPFFVLNSDVICDYPF 117
+ + + F I + E LGT G L + +LK S FV+++DV C +P
Sbjct: 66 KDFINEVASHFPSFNRIKYLREYNCLGTGGGLYHFRDQILKGHTSNVFVMHADVCCSFPL 125
Query: 118 KELADFHQAHGGKGTIVATKV--DEPSKYGVIVHDIATPNLIDRFVEKPVEFVGNRINAG 175
+EL + H T++ATKV ++ S +G +V + +T ++ +V+KP ++ N I+ G
Sbjct: 126 QELLNVHHEKKALVTLMATKVSKEDASNFGCLVEEPSTGRVL-HYVDKPSSYLSNIISCG 184
Query: 176 LYILNPEVIDLI----DLKPTSIEKET------------------FPILVEQ-KSLYSFD 212
+YI + + D I + + +EK+ P+ + K++Y+++
Sbjct: 185 IYIFDASIFDEIKKAYERRLEEVEKQLRSLDEGMEDYLSLETDVLAPLCSDSSKAIYAYN 244
Query: 213 LEGYWMDVGQPKDFLSGTVLYLNSLSKRDPAKLAKGE-NIVGNVLVDPTAKISPTAKVGP 271
+W + + LYL E I+ V + P A +S AK+GP
Sbjct: 245 TPEFWRQIKTAGSAVPANSLYLQKAYHDGTLPKPDTEAEIIQPVFIHPNAIVSKGAKIGP 304
Query: 272 DVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTVGKWARLEG-------- 323
+V IG V I DG RI S+ + I +A+V +I+ + +GKW+R+EG
Sbjct: 305 NVSIGARVRIEDGARIRNSIIQEDCEISANAVVLHSILSRHCKIGKWSRVEGSPTLPSQH 364
Query: 324 -------------VTVLGDDVEVKDEIYINGGKVLPHKSISVNVPKEAII 360
+TV+G D V DE+ + VLPHK I V + E ++
Sbjct: 365 STTIMRNSVKVQAITVMGADCIVHDEVRVQNCLVLPHKEIKVGLVGEIVM 414
>Hs14734024 [GMO] KOG1460 GDP-mannose pyrophosphorylase
Length = 225
Score = 114 bits (284), Expect = 3e-25
Identities = 65/199 (32%), Positives = 100/199 (49%), Gaps = 32/199 (16%)
Query: 194 IEKETFPILVEQKSLYSFDLEGYWMDVGQPKDFLSGTVLYLNSLSKRDPAKLAK----GE 249
+E++ F L Q +Y +G W + L + LYL+ P +LAK G
Sbjct: 27 LEQDVFSALAGQGQIYVHLTDGIWSQIKSAGSALYASRLYLSRYQDTHPERLAKHTPGGP 86
Query: 250 NIVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTII 309
I GNV + PTAK++P+A +GP+V IG V +G+GVR+ S+ L + +++H V +I+
Sbjct: 87 WIRGNVYIHPTAKVAPSAVLGPNVSIGKGVTVGEGVRLRESIVLHGATLQEHTCVLHSIV 146
Query: 310 GWNSTVGKWARLEG----------------------------VTVLGDDVEVKDEIYING 341
GW STVG+WAR+EG +T+LG V + E+ I
Sbjct: 147 GWGSTVGRWARVEGTPSDPNPNDPRARMDSESLFKDGKLLPAITILGCRVRIPAEVLILN 206
Query: 342 GKVLPHKSISVNVPKEAII 360
VLPHK +S + + I+
Sbjct: 207 SIVLPHKELSRSFTNQIIL 225
>SPAC8C9.15c [J] KOG1461 Translation initiation factor 2B epsilon subunit
(eIF-2Bepsilon/GCD6)
Length = 678
Score = 59.7 bits (143), Expect = 6e-09
Identities = 93/393 (23%), Positives = 159/393 (39%), Gaps = 69/393 (17%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
++ ++L Y R RPLTL P+ L+ N P+I + E LA AGV ++ + +
Sbjct: 18 LQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQEVYVFCCAHAGQI 77
Query: 61 VETLKKYEDEFGVSITFSVET----EPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYP 116
E ++K + S FSV T E L L+ +S + S F +++ DV+ + P
Sbjct: 78 REYIEKSKWNL-PSSPFSVNTIVSRESLSVGDALRELDS-KQLITSDFILVSGDVVSNVP 135
Query: 117 FKELADFH--QAHGGKGTIVATKVDEPSKY-GVIVHDIATPNLIDRFVEKPVEFVGNRIN 173
E+ H + K I+ V E S + ++ +ID+ + V + N
Sbjct: 136 LNEVLKEHRKRREDDKNAIMTMVVREASPFHRTRARTESSVFVIDKKTSQCVHYQANERG 195
Query: 174 AGLYILNPEVI----------DLIDLKPTSIEKETFPILVEQKSLYSFDLEGYWMDVGQP 223
++PE+ DLID + + + E +FD + D+
Sbjct: 196 KHYVSMDPEIFNEHEELEVRNDLIDCQIDICSNDVPALFTE-----NFD----YQDI--R 244
Query: 224 KDFLSGTVLYLNSLSKRDPAKLAKGENIVGNV----LVDPTAKISPTAKVGP-------- 271
KDF+ G VL + L K+ +AK EN V D +K + V P
Sbjct: 245 KDFVYG-VLTSDLLGKKIHCHVAK-ENYAARVRSLQTYDAISKDVLSRWVYPFVPDSNLL 302
Query: 272 ---------------DVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTVG 316
DVV+ + +I R++ + + + D ++V +TIIG N T+G
Sbjct: 303 NQTFSYQRHQIYKEEDVVLARSCIIK-----ARTLIGAYTKVGDASVVANTIIGRNCTIG 357
Query: 317 KWARLEGV-----TVLGDDVEVKDEIYINGGKV 344
++ V+GD+ + I N K+
Sbjct: 358 SNCSIDSAFLWEDVVIGDNCRIGKAILANSVKI 390
>Hs9966779 [J] KOG1462 Translation initiation factor 2B gamma subunit
(eIF-2Bgamma/GCD1)
Length = 452
Score = 54.7 bits (130), Expect = 2e-07
Identities = 92/440 (20%), Positives = 169/440 (37%), Gaps = 115/440 (26%)
Query: 2 KGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVMV 61
+ +++ G G+R+ LT ++PKPL+ GN+P+I + + L G ++++ +V
Sbjct: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT--RDVQK 61
Query: 62 ETLKKYEDEFGVSITFSVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVICDYPFKELA 121
+++ + I + +GTA L+ LK D VL+ D+I D E+
Sbjct: 62 ALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD---VLVLSCDLITDVALHEVV 118
Query: 122 DFHQAH-------------------GGKGTIVATK------VDEPSKYGVIVHDIATPNL 156
D +A+ G KG A + VD K + + + A +L
Sbjct: 119 DLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEA--DL 176
Query: 157 IDRFVEK--------PVEFVGNRINAGLYILNPEVIDLI--DLKPTSIEKETFPILV--- 203
+ V K + F ++A LY L ++D + + TSI E P LV
Sbjct: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236
Query: 204 -----------------EQKSLYSFDLEGY-----------------------WMDVGQP 223
++K L S D+ + W D+ +
Sbjct: 237 FSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRS 296
Query: 224 ---------KDFLSGTV----LY----------LNSLSKRDPAKLAKGENIVGNVLVDPT 260
K+ L V LY L++L +P + IV LV
Sbjct: 297 QVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEP-PVHSSAQIVSKHLVGVD 355
Query: 261 AKISPTAKVGPD-----VVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIGWNSTV 315
+ I P ++G VIG + +I D V IT + +++ +++ + ++ ++I N+ +
Sbjct: 356 SLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVI 415
Query: 316 GKWARLEGVTV-LGDDVEVK 334
K A ++ + G +E K
Sbjct: 416 EKGADIKDCLIGSGQRIEAK 435
>CE23548 [J] KOG1462 Translation initiation factor 2B gamma subunit
(eIF-2Bgamma/GCD1)
Length = 404
Score = 54.7 bits (130), Expect = 2e-07
Identities = 89/394 (22%), Positives = 163/394 (40%), Gaps = 65/394 (16%)
Query: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALAAAGVTDIVLAVNYRPEVM 60
M+G++L G GTR+ LT V K L+ PM L+ + +L G+TDI + V EV+
Sbjct: 4 MQGILLCSGGGTRMPVLTRHVQKCLLPVVGVPMFLYPLSSLLRTGITDIKIFVR---EVL 60
Query: 61 VETLK------KYEDEFGVSITF-SVETEPLGTAGPLKLAESVLKKDNSPFFVLNSDVIC 113
TL+ K +++ I + V E GTA LK S + KD +++ D I
Sbjct: 61 QLTLEKEVKKSKLLEKYPAHIEYICVNQEDFGTADLLKNHHSKITKD---ALIVSCDFIS 117
Query: 114 DYPFKELADFHQAHGGKGTIVA-------------TKVDEPSKYGVIV------------ 148
D L DF +A T+VA +K +P V+
Sbjct: 118 DASLIPLVDFFRA--TNSTLVALIADTCVNAPAPGSKSKKPKATDVMAIVESTGQLAFLC 175
Query: 149 --HDIATPNLIDRFVE--KPVEFVGNRINAGLYILNPEV-IDLIDLKPTSIEKETF-PIL 202
D P ++++ ++ ++ + +Y + +V ++L K S K F P+L
Sbjct: 176 GDDDFDAPLVMEKSLKIFPSIKLTSKYNDCHVYAIRHKVLLNLSKSKHISSFKADFVPLL 235
Query: 203 VEQKSLYSFDLEGYWMDVGQPKDFLS------GTVLYLNSLSKRDPAKL------AKGEN 250
++++ D++ + + F++ G+ +N ++ +L K N
Sbjct: 236 IDKQFEPDSDIKCFAYRLPHENGFVTAHANTLGSYFEVNKAIQKSFTRLMEYRGNGKNFN 295
Query: 251 IVGNVLVDPTAKISPTAKVGPDVVIGPNVVIGDGVRITRSVALSNSHIKDHALVKSTIIG 310
+ + ++I +A++ D VI I D RI L K+ + K +IG
Sbjct: 296 YKTDKIAAHESRIEESAEIDKDSVI-KRSFISDNCRIGEKTKL-----KESIIAKGVVIG 349
Query: 311 WNSTVGKWARLEGVTVLGDDVEVKDEIYINGGKV 344
+++ +GV + G++ +V + I KV
Sbjct: 350 NGASISNSIICDGVEI-GENADVTNCIVAKDQKV 382
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.139 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,402,483
Number of Sequences: 60738
Number of extensions: 993988
Number of successful extensions: 2333
Number of sequences better than 1.0e-05: 21
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2217
Number of HSP's gapped (non-prelim): 35
length of query: 361
length of database: 30,389,216
effective HSP length: 108
effective length of query: 253
effective length of database: 23,829,512
effective search space: 6028866536
effective search space used: 6028866536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)