ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1594 good D KOG2688 Cell cycle control, cell division, chromosome partitioning Transcription-associated recombination protein - Thp1p
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1594 561809 560538 -424
(424 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR084w [D] KOG2688 Transcription-associated recombination prote... 157 3e-38
SPAC1B3.08 [D] KOG2688 Transcription-associated recombination pr... 102 8e-22
Hs8922987 [D] KOG2688 Transcription-associated recombination pro... 86 1e-16
SPBC1105.07c [D] KOG2688 Transcription-associated recombination ... 70 6e-12
CE29189 [D] KOG2688 Transcription-associated recombination prote... 62 2e-09
7294700_1 [D] KOG2688 Transcription-associated recombination pro... 53 8e-07
>YJR084w [D] KOG2688 Transcription-associated recombination protein - Thp1p
Length = 423
Score = 157 bits (397), Expect = 3e-38
Identities = 113/400 (28%), Positives = 192/400 (47%), Gaps = 44/400 (11%)
Query: 36 SFKLPEFEKVKQLIEICNELKRTYKKEPN--GGSPQLFHLALEQLRVLNRIYENRTNWMT 93
S +L F ++ +++ +R+ KK+ + +L LA EQL++ NRI E TNW+
Sbjct: 46 SVRLQRFYQLGVDLKLKYSKRRSLKKQGRIKNATEELLRLANEQLKLFNRIVERETNWII 105
Query: 94 ELLYQSGEQLYAIANKLDEIQNKLXXXXXXXXXXXXXSYLIQAGRVMHMTLNICFKDRNE 153
L+ +QL +AN+ E+ + + GR +H + IC DRN
Sbjct: 106 YPLWVMAKQLIRLANESSELNK---------------DSIEECGRTIHRSFTICLNDRNP 150
Query: 154 RVDENRKIGVFYIGTLLFKLYNRIKAYGLLNNMCKVFESHFN--EIGPYLSRI--NNDLI 209
R++EN+KIG + L F +Y+R+ ++ N+ KV ES N +I P + +
Sbjct: 151 RLNENKKIGCYMFANLEFSIYHRLSNKDMIKNLVKVLESRVNARDIPPLNKSLAMEHKSQ 210
Query: 210 VIRFKFYMGLYYGYEKNNYALGFKWLQETFDIC-TLYESIPSTYKVRSQ---VLIYLIPM 265
V+ + +Y+G YYG +N++ GF L E C LY + ++ Q ++I L+P+
Sbjct: 211 VVLYNYYLGQYYGCLENDHERGFFHLNEALLQCPMLYVESTGKFVLQGQMEKIMILLVPL 270
Query: 266 RILHLRHYPR-----LAPLRRTYPSVAKIYTMLVKSLCTGNLKLYEKFIEDNEFYLVKRN 320
+L R YP +A + ++++Y LV+S+ +GNL LYE +E + + +
Sbjct: 271 ALLTKRLYPHWDHPVIAGVITRSKRLSQVYPTLVRSVISGNLSLYEATAASHERFFLSQG 330
Query: 321 LYXXXXXXXXXXXXXXXXXAWIL-NGGNTKVPLDMLAKAFQISRGTPCHVTENVAPNHDQ 379
L+ W N + +PL +L Q + + N D+
Sbjct: 331 LHVVITLLREVVFTRLVQRCWQWGNDRKSIMPLKILLATKQ----------HDSSANEDE 380
Query: 380 E--LDELECILATLISKNYIKGYLSHSHR-VMMTSKTPFP 416
E LD LEC LA+ I+ ++ YLSHS+R ++ + K PFP
Sbjct: 381 EEQLDALECRLASAIASGLLRAYLSHSNRCIVFSKKEPFP 420
>SPAC1B3.08 [D] KOG2688 Transcription-associated recombination protein - Thp1p
Length = 423
Score = 102 bits (255), Expect = 8e-22
Identities = 82/280 (29%), Positives = 136/280 (48%), Gaps = 26/280 (9%)
Query: 138 RVMHMTLNICFKDRNERVDENRKIGVFYIGTLLFKLYNRIKAYGLLNNMCKVFESHFNEI 197
R+++ IC DR + +RK G +YI LLFKLY R+ L NN+ + + E+
Sbjct: 164 RLINRAFTICINDRAP-LSTSRKWGAYYIMGLLFKLYLRLDCVHLTNNVLRAMK--VVEL 220
Query: 198 GPYLSRINNDLIVIRFKFYMGLYYGYEKNNYALGFKWLQETFDICTLYESIPSTYKVRSQ 257
P +S +VI F +Y+G+ + NY L+ F +C ++ ++
Sbjct: 221 -PDISLFPKSHVVI-FHYYLGIV-AFLNQNYKNASAELEIAFSLC--HKGYNRNLEL--- 272
Query: 258 VLIYLIPMRILHLRHYPRLAPLRRTYPSVAKIYTMLVKSLCTGNLKLYEKFIEDNEFYLV 317
+L Y IP RIL + H L +P++A +Y L ++L +GNL + K ++ NE L
Sbjct: 273 ILSYWIPTRIL-VNHQLPTKNLLSKFPNLASVYIPLTRALKSGNLGEFGKCLQKNETLLA 331
Query: 318 KRNLYXXXXXXXXXXXXXXXXXAWILNGGNTKVPLDMLAKAFQISRGTPCHVTENVAPNH 377
K +Y WI+ G +T++P+ + A Q++ GT
Sbjct: 332 KTKIYLTLEGTRDLCIRNLFRKTWIICGKSTRLPVSVFQIALQVA-GT------------ 378
Query: 378 DQELDELECILATLISKNYIKGYLSHS-HRVMMTSKTPFP 416
D +E ILA +ISK Y++GY+S + V++++K PFP
Sbjct: 379 DLPKLHVEAILANMISKGYMRGYISRNFETVVLSAKDPFP 418
>Hs8922987 [D] KOG2688 Transcription-associated recombination protein - Thp1p
Length = 453
Score = 85.5 bits (210), Expect = 1e-16
Identities = 74/334 (22%), Positives = 147/334 (43%), Gaps = 43/334 (12%)
Query: 90 NWMTELLYQSGEQLYAIANKLDEIQNKLXXXXXXXXXXXXXSYLIQAGRVMHMTLNICFK 149
NW ++Y L AN D+ K L +A ++ +C
Sbjct: 156 NWALPVMYAVALDLRVFANNADQQLVK-------KGKSKVGDMLEKAAELLMSCFRVCAS 208
Query: 150 DRNERVDENRKIGVFYIGTLLFKLYNRIKAYGLLNNMCKVFESHFNEIGPYLSRINNDLI 209
D +++++K G+ ++ LFK+Y +I L + + +S S + +D
Sbjct: 209 DTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDS---------SNLKDDYS 259
Query: 210 V---IRFKFYMGLYYGYEKNNYALGFKWLQETFDICTLYESIPSTYKVRSQVLIYLIPMR 266
+ +K+Y+G ++ +++ ++L F+ C S+ K + +LIYL+P++
Sbjct: 260 TAQRVTYKYYVGRKAMFD-SDFKQAEEYLSFAFEHCHR-----SSQKNKRMILIYLLPVK 313
Query: 267 ILHLRHYPRLAPLRRTYPSVAKIYTMLVKSLCTGNLKLYEKFIEDNEFYLVKRNLYXXXX 326
+L L H P + L++ + + + +++ GNL L + + +E + ++ ++
Sbjct: 314 ML-LGHMPTVELLKKYH---LMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLTLE 369
Query: 327 XXXXXXXXXXXXXAWILNGGNTKVPLDMLAKAFQISRGTPCHVTENVAPNHDQELDELEC 386
I+ N + +L K Q+S V D ++DE++C
Sbjct: 370 KLK------------IITYRNLFKKVYLLLKTHQLSLDAFL-VALKFMQVEDVDIDEVQC 416
Query: 387 ILATLISKNYIKGYLSHSHRVMMTSK-TPFPGLA 419
ILA LI ++KGY+SH H+ ++ SK PFP L+
Sbjct: 417 ILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 450
>SPBC1105.07c [D] KOG2688 Transcription-associated recombination protein - Thp1p
Length = 442
Score = 70.1 bits (170), Expect = 6e-12
Identities = 85/368 (23%), Positives = 154/368 (41%), Gaps = 67/368 (18%)
Query: 80 VLNRIYENRTNWMTELLYQSGEQLYAIANKLDEIQNKLXXXXXXXXXXXXXS-------- 131
+L +Y N T + + G L I ++ ++ KL S
Sbjct: 91 LLQNLYSNLTTCFSHI---DGAWLCTIVKRVSKLYVKLSLQLDTSTPTLEDSFDGNGFIQ 147
Query: 132 --YLIQAGRVMHMTLNICFKDRNERVDENRKIGVFYIGTLLFKLYNRIKAYGLLNNMCKV 189
Y+ A R + T N DR + ++ ++K +F I LL LY R+K +C+
Sbjct: 148 RKYVSDASRNVLRTFNSILSDRQQNINPSKKDAIFCIANLLCLLYFRLKQI----RLCQT 203
Query: 190 FESHFNEIGPYLSRINNDLIVIRFKFYMGLYYGYEKNNYA----LGFKWLQETFDICTLY 245
+++ G +SR +V F++Y+G + Y++ + L F +LQ D C
Sbjct: 204 IQANVISSGADISRATMAELV-TFRYYLGRCHLYQRKIHQAKDHLLFSFLQ-CPDEC--- 258
Query: 246 ESIPSTYKVRSQVLIYLIPMRILHLRHYPRLAPLRRTYPSVAKIYTMLVKSLCTGNLKLY 305
Y + LIYL +L L P L + + A + L+K+L +G++K +
Sbjct: 259 ------YHQKRLSLIYLTTC-LLILGKSPTKGLLEKYKLTAA--FEPLIKALKSGDIKSF 309
Query: 306 EKFIEDN--EFYLVKRNLYXXXXXXXXXXXXXXXXXAWILNGGNTKVPLDMLAK----AF 359
+EDN + +KR +Y +L+ + ++ K F
Sbjct: 310 RLSLEDNSRRKWFIKRGIYLT-----------------LLDRCEIILWRNLFRKVFLFTF 352
Query: 360 QISRGTPCHVTENV--------APNHDQELDELECILATLISKNYIKGYLSHSHRVMMTS 411
+ S+ TP HV+ + ++ ++D++ECI +LI + YIKGY+ H+ ++
Sbjct: 353 EQSQKTP-HVSGSYLLTAARLSTNDNSYDMDDVECICVSLIDQGYIKGYIIHASSTLVLK 411
Query: 412 KTPFPGLA 419
K P G +
Sbjct: 412 KDPSFGFS 419
>CE29189 [D] KOG2688 Transcription-associated recombination protein - Thp1p
Length = 413
Score = 61.6 bits (148), Expect = 2e-09
Identities = 65/293 (22%), Positives = 121/293 (41%), Gaps = 35/293 (11%)
Query: 131 SYLIQAGRVMHMTLNICFKDRNERVDENRKIGVFYIGTLLFKLYNRIKAYGLLNNMCKVF 190
S+ A + + C D + +K+ + + LF++Y +I LL + +
Sbjct: 147 SFFESAAKAITECYRTCVSDVHAEEGTTKKVAMLNMTNQLFQIYFQINKLNLLKPLIRAI 206
Query: 191 ESHFNEIGPYLSRINNDLIV---IRFKFYMGLYYGYEKNNYALGFKWLQETFDICTLYES 247
++ + +D ++ + + +++G ++ + L K L F C
Sbjct: 207 DN--------CGSLYHDFLMSDKVAYNYFLGRKAMFDAD-LNLAEKSLLYAFRNCPA--- 254
Query: 248 IPSTYKVRSQVLIYLIPMRILHLRHYPRLAPLRRTYPSVAKIYTMLVKSLCTGNLKLYEK 307
+ + ++LIYLIP+++ L H P + L Y + +V + GNL +
Sbjct: 255 --DSMSNKRKILIYLIPVKMF-LGHMPT-SQLLHEYR--LDEFQDVVAGVKDGNLAQLDG 308
Query: 308 FIEDNEFYLVKRNLYXXXXXXXXXXXXXXXXXAWILNGGNTKVPLDMLAKAFQISRGTPC 367
+ NE + +K ++ + G ++PLD A + T
Sbjct: 309 ALAANEAFFIKCGIFLMLEKLRMITFRTLFKKVSQIVG-TAQIPLDAFQTALRFVGVT-- 365
Query: 368 HVTENVAPNHDQELDELECILATLISKNYIKGYLSHSHRVMMTSK-TPFPGLA 419
D ++DELECI+A LI+ IKGYLSH H+ ++ SK FP L+
Sbjct: 366 ----------DVDMDELECIIANLIASKKIKGYLSHQHQKLVISKMNAFPTLS 408
>7294700_1 [D] KOG2688 Transcription-associated recombination protein - Thp1p
Length = 372
Score = 53.1 bits (126), Expect = 8e-07
Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 33/255 (12%)
Query: 146 ICFKDRNERVDENRKIGVFYIGTLLFKLYNRIKAYGLLNNMCKVFES-HFNEIGPYLSRI 204
+C D ++ +++G+ + LFK+Y RI L + + ++ F + P +I
Sbjct: 149 VCAADGRASEEDTKRLGMMNLVNQLFKIYFRINKLHLCKPLIRAIDNCIFKDSFPLPEQI 208
Query: 205 NNDLIVIRFKFYMGLYYGYEKNNYALGFKWLQETFDICTLYESIPSTYKVRSQ-VLIYLI 263
+K+++G ++ +NY ++L F C P + + +LIYL+
Sbjct: 209 T-------YKYFVGRRAMFD-SNYQAAVQYLSYAFSNC------PDRFASNKRLILIYLV 254
Query: 264 PMRILHLRHYPRLAPLRRTYPSVAKIYTMLVKSLCTGNLKLYEKFIEDNEFYLVKRNLYX 323
P+++L L + P + L+R Y + ++ L ++ GN+ +++ + D E L++ +Y
Sbjct: 255 PVKML-LGYLPSKSLLQR-YDLL--LFLDLAMAMKAGNVNRFDEIVRDQELVLIRSGIYL 310
Query: 324 XXXXXXXXXXXXXXXXAWILNGGNTKVPLDMLAKAFQISRGTPCHVTENVAPNHDQELDE 383
+++ K+ Q+ G V D LDE
Sbjct: 311 LVEKLKFLVYRNLFKKVFVIR------------KSHQLDMGDFLSALHFVGLT-DVSLDE 357
Query: 384 LECILATLISKNYIK 398
CI+A LI IK
Sbjct: 358 THCIVANLIYDGKIK 372
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.140 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,785,728
Number of Sequences: 60738
Number of extensions: 1024379
Number of successful extensions: 2135
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2122
Number of HSP's gapped (non-prelim): 8
length of query: 424
length of database: 30,389,216
effective HSP length: 109
effective length of query: 315
effective length of database: 23,768,774
effective search space: 7487163810
effective search space used: 7487163810
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)