ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1684 good R KOG3780 General function prediction only Thioredoxin binding protein TBP-2/VDUP1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1684 593785 590426 -1120
(1120 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL101c [R] KOG3780 Thioredoxin binding protein TBP-2/VDUP1 538 e-152
YPR030w [R] KOG3780 Thioredoxin binding protein TBP-2/VDUP1 295 4e-79
YJL084c [R] KOG3780 Thioredoxin binding protein TBP-2/VDUP1 55 8e-07
>YBL101c [R] KOG3780 Thioredoxin binding protein TBP-2/VDUP1
Length = 1117
Score = 538 bits (1386), Expect = e-152
Identities = 327/879 (37%), Positives = 470/879 (53%), Gaps = 78/879 (8%)
Query: 224 SATGSQISNT----VVNRKKTAKTCLLNYLADRGLLRPRLLSSKNGVTFHVATSGDNIFL 279
+ S +S+T + N KK + L+ YL RGLL P+ + S + ++TSG+++FL
Sbjct: 172 AVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYLKISISTSGESVFL 231
Query: 280 PTISPTDDEYLNHLSRLNXXXXXXXXXXXLERLATRDPSEFS-RSDVVPTGSHSTIFANR 338
PTIS DDEYL+ L+ LN ++ + ++ + S + T S +I NR
Sbjct: 232 PTISSNDDEYLSRLNGLNDGTDDAEADFFMDGIDQQEGNTPSLATTAAATESGGSINENR 291
Query: 339 ENESLATGNSEFASSNPVQSSLXXXXXXXXXXXIEPTDSYTAMDDDSPAADSENIPYNIA 398
+ + + S + ++ S DS + Y+IA
Sbjct: 292 DTLLRENNSGDHPGSG------------------------SELNTRSVEIDSSMVSYSIA 327
Query: 399 VIMSLKKQMELSSVKAELYSRVRVYWSNGLPPDKMETEEYYTGGHLDWEFNTDNYNLYVG 458
VI+S+KK + ++ EL SRV+V+W+ G+PP K EE+Y + W N +N++L+V
Sbjct: 328 VIVSVKKPTRFTDMQLELCSRVKVFWNTGVPPTKTFNEEFYNAASMKWNLNDENFDLFVP 387
Query: 459 FSAADQELVIIENTQNLCRRKNFKNIQDFGDRPYLKKQKTKDNFLKDINEASDTNSC-TF 517
S + + +I EN N + + FKNI +R YL K KTK + L I D N +
Sbjct: 388 LSISPDDQMI-ENNSNDRQMRLFKNIPT-EERLYLDKTKTKASLLNAI----DVNKTHLY 441
Query: 518 QPGDYIFIVPVVFANNIPETICLPSARVNYHFRCAAKVIXXXXXXXXXXXXXXXXXXXXX 577
QPGDY+F+VPVVF+N+IPETI LPSARV+Y R A K I
Sbjct: 442 QPGDYVFLVPVVFSNHIPETIYLPSARVSYRLRLATKAINRKGFYRQDSNSPQPIVSPDS 501
Query: 578 XXXXXXXXXXAFQXXXXXXXXXXXXAGDGTTSHXXXXXXXXXXXXXNHLHLPSYHGISKT 637
+ +H NHLH+ S+ ++
Sbjct: 502 SSSLSSTTSSL-----------KLTETESAQAHRRISNTLFSKVK-NHLHMSSHQLKNEE 549
Query: 638 DYQKMVYSHMALNLVRTPPLRSISTADKPIYINRIWTDSLSYEISFGQKYVPLDVEIPXX 697
++ +++ + ++RTPP ++STA+KPIYINR+WTDSLSYEISF QKYV L+ E+P
Sbjct: 550 SGEEDIFAEYPIKVIRTPPPVAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIK 609
Query: 698 XXXXXXXXXXXXXRIRICVVEKITYVSKNLQYEFDQVELVANDPYSPYYPEFSSRRKPER 757
RI + + E++T+VSK +YE+DQ + VA DPY+PYY +F+S+R+ ER
Sbjct: 610 IKLAPICKNVCVKRIHVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKER 669
Query: 758 ILPLLEIRTRDKGGRAMKEEIVENCKSDNLLCYSTVRDE-----NTNSNVEMVEALTIDT 812
+ L EIRT++KG RA++EEIVEN +DNLL YS D+ N + + E + I+T
Sbjct: 670 SVSLFEIRTKEKGTRALREEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGITEPIIIET 729
Query: 813 KLKFPKYKLLNKKSARSVPPYGIDEFTQLENIKSNXXXXXXXXXXXVIDFLXXXXXXXXX 872
KLKFPKY+ L+K++A+ +PPYGID +T + N + VI FL
Sbjct: 730 KLKFPKYEDLDKRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSH 789
Query: 873 XXXXX--LDLPKPTTKFRTNSNLPIVNHTRLNEPKRGLYASSVNFSHINVKHKLEIMLRI 930
D T ++NS LP+ HTRLN PKRGLY S++FS++ +HKLEIMLRI
Sbjct: 790 EENEKPVYDPKFHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRI 849
Query: 931 SKPDATDPTKQRHFEVLIDTPVHVVSELCTSDNLELPTYAMATMSHPDKDTTISFHE--- 987
SKPD P+K RH+EVLIDTP+ +VSE C S N+ELPTY MATM +S +
Sbjct: 850 SKPDPECPSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFF 909
Query: 988 -----PLPSFEEAISVPNSPRVSPIGTPQLRATYDPDDLSIQQLMLSRAST--------- 1033
P P+FEEAISVP SP VSP+G+P + A+YDPD LSIQQL LSR ++
Sbjct: 910 GNTCPPPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSD 969
Query: 1034 ------QNVDDLQSASSVARRYSNIDEMMGQSGLTTARS 1066
N + + +A+++ SN + G SG AR+
Sbjct: 970 DAGVPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARA 1008
>YPR030w [R] KOG3780 Thioredoxin binding protein TBP-2/VDUP1
Length = 1121
Score = 295 bits (754), Expect = 4e-79
Identities = 166/409 (40%), Positives = 242/409 (58%), Gaps = 37/409 (9%)
Query: 638 DYQKMVYSHMALNLVRTPPLRSISTADKPIYINRIWTDSLSYEISFGQKYVPLDVEIPXX 697
D + + LNLVRTPP S++TA+KP+YIN++W + LSYEISF QKYVPL+ EIP
Sbjct: 603 DSEDTINLQYPLNLVRTPPEISVTTANKPLYINKVWENCLSYEISFAQKYVPLNGEIPIT 662
Query: 698 XXXXXXXXXXXXXRIRICVVEKITYVSKNLQYEFDQVELVANDPYSPYYPEFSSRRKPER 757
RIR+ EKI+Y SK+ QY+FDQ++ +A+DP +PY+ + R+K +R
Sbjct: 663 IKVAPLVKSLSVKRIRVSCREKISYRSKDYQYDFDQLDPLASDPCNPYHMRYLVRKKKDR 722
Query: 758 ILPLLEIRTRDKGGRAMKEEIVENCKSDNLLCYSTVRDENTNSNVEMVEALTIDTKLKFP 817
LPL E+ ++ G +++EE+V N DNLL Y++ ++ N ++ E+ T+ TKLKFP
Sbjct: 723 SLPLFEVASKCTSGPSIREEVVTNTVDDNLLAYTSSKE--NNKDIPFSESFTVKTKLKFP 780
Query: 818 KYKLLNKKSARSVPPYGIDEFTQLENIKSNXXXXXXXXXXXVIDFLXXXXXXXXXXXXXX 877
KY ++ A S+PPYGID F + IK V+ FL
Sbjct: 781 KYCEVDATKAASLPPYGIDLF---DPIKDPTQSENTSNNGNVLGFLVGRPNRASKTVH-- 835
Query: 878 LDLPK-------------PTTKFRTNSNLPIVNHTRLNEPKRGLYASSVNFSHINVKHKL 924
+P+ T +T+SN+PI ++TRLN+P+RGLY S++F +I HKL
Sbjct: 836 -KIPQDKNHNEVNDTNGNSNTSLQTSSNVPIQHYTRLNKPRRGLYLDSMHFKNIQCSHKL 894
Query: 925 EIMLRISKPDATDPTKQRHFEVLIDTPVHVVSELCTSDNLELPTYAMATMSHPDKDTTIS 984
EI+LR+SK D+ RH+EV++DTP++++S+LC + N++LPTY MA TT S
Sbjct: 895 EIVLRVSKTDSGSSKIIRHYEVIVDTPIYLISDLCNTSNIDLPTYDMA--------TTES 946
Query: 985 FHEPLPSFEEAISVPNSPRVSPIGTPQLRATYDPDDLSIQQLMLSRAST 1033
P+FEEA SV SPR S +Y PDD+S+QQL LSR+++
Sbjct: 947 SKVLPPTFEEATSVSASPRSS--------VSYYPDDISMQQLNLSRSTS 987
Score = 145 bits (366), Expect = 3e-34
Identities = 107/358 (29%), Positives = 166/358 (45%), Gaps = 23/358 (6%)
Query: 218 RVSTAFSATGSQISNTVVNRKKTAKTCLLNYLADRGLLRPRLLSSKNGVT-FHVATSGDN 276
++S+ S I++ N L +YLADRG ++ L +K V +ATS ++
Sbjct: 155 QISSNNDIVRSFITHHASNSTMFINRVLSDYLADRGFIKQTPLYNKKSVLEISIATSAES 214
Query: 277 IFLPTISPTDDEYLNHL-SRLNXX------XXXXXXXXXLERLATRDP-SEFSRSDVVPT 328
+FLPT + EYL+ + LN L T D +E + + P
Sbjct: 215 VFLPTTKSDETEYLSLIHGSLNQARTQPVGSTNTAESDFLPSCPTMDTLNENNDLSLFPL 274
Query: 329 GSHSTIFAN--RENESLATGNSEFASSNPVQSSLXXXXXXXXXXXIEPTDSYTAMDDDSP 386
+ T +N R ++ T NS+ AS ++ ++ + + P
Sbjct: 275 HTQRTSPSNTARTGNAMDTSNSDRASPASNNNTTDADSFVASGNNNPMNNNNSPARNRHP 334
Query: 387 AADSENIP---------YNIAVIMSLKKQMELSSVKAELYSRVRVYWSNGLPPDKMETEE 437
+ S ++P ++ A+I SL K LS +K EL S VRV W NGLPP K EE
Sbjct: 335 NSHSRSLPNAWNSQMPSFSFALIFSLNKSTTLSDIKVELTSNVRVVWFNGLPPTKNVNEE 394
Query: 438 YYTGGHLDWEFNTDNYNLYVGFSAADQELVIIENTQNLCRRKNFKNIQDFGDRPYLKKQK 497
Y G LDW N DN+NL++ A L I+EN N + K + + R + K
Sbjct: 395 CYNIGSLDWTLNADNFNLFIP-QGAKSPLDIVENHSNNRKLKVLQKLSMRKRRSFSNKAV 453
Query: 498 TKDNFLKDINEASDTNSCTFQPGDYIFIVPVVFANNIPETICLPSARVNYHFRCAAKV 555
++N L ++N ++ TN G Y+F +P+V A+ IPE++ PSARV+Y R A K+
Sbjct: 454 LRENILNNLNASNSTNK--LNAGVYVFTIPIVLASRIPESLYYPSARVSYSLRLATKL 509
>YJL084c [R] KOG3780 Thioredoxin binding protein TBP-2/VDUP1
Length = 1046
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/128 (29%), Positives = 66/128 (50%), Gaps = 11/128 (8%)
Query: 914 NFSHINVKHKLEIMLRISKPDATDPTKQRHFEVLIDTPVHVVSELCTSDNLELPTYAMAT 973
++ +I H ++I LR+S+ K++H+E+ ID+P+HV+ LC+ N LP+Y
Sbjct: 487 SYENIKANHWIKICLRLSR---VVDNKRKHYEISIDSPIHVLHRLCSHANTLLPSYDGHP 543
Query: 974 MSHPDKDTTISFHEPLPSFEEAISVPNSPRV----SPIGTPQLRATYDPDDLSIQQL--- 1026
S P K+T S L S ++ I++ ++ + + +P L P D+ I L
Sbjct: 544 ASFP-KETDSSISSILESSDDNINLYHNSNIFFPKEVLSSPVLSPNVQPLDILIPHLPST 602
Query: 1027 MLSRASTQ 1034
L+R S Q
Sbjct: 603 SLTRNSRQ 610
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,695,506
Number of Sequences: 60738
Number of extensions: 2096663
Number of successful extensions: 3865
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3842
Number of HSP's gapped (non-prelim): 12
length of query: 1120
length of database: 30,389,216
effective HSP length: 117
effective length of query: 1003
effective length of database: 23,282,870
effective search space: 23352718610
effective search space used: 23352718610
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)