ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1834 good G KOG0234 Carbohydrate transport and metabolism Fructose-6-phosphate 2-kinase/fructose-2,6-biphosphatase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1834 648884 647520 -455
(455 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL136c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-bi... 246 5e-65
YIL107c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-bi... 89 2e-17
YJL155c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-bi... 64 5e-10
Hs4505745 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-... 59 1e-08
CE29606 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-bi... 59 1e-08
CE23252 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-bi... 59 1e-08
CE04687 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-bi... 58 3e-08
SPAC222.13c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-2... 55 2e-07
Hs4758900 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-... 55 3e-07
>YOL136c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 397
Score = 246 bits (628), Expect = 5e-65
Identities = 135/330 (40%), Positives = 186/330 (55%), Gaps = 52/330 (15%)
Query: 92 LTIQFGNKRQNLN--------HKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSI 143
L I KR N + +KF ++LIGLPATGKSTIS HLI L ++ T LRC +
Sbjct: 74 LPITLNYKRDNADPTYTNGKVNKFMIVLIGLPATGKSTISSHLIQCLKNNPLTNSLRCKV 133
Query: 144 FNAGNVRRKLSTRRQVSPFMAPELNKSEEDVFNPKNSHKKEEYARIALSKLLNDLKQDRC 203
FNAG +RR++S P + N S ED+FNPKN+ KKE YARI L KL +++ D C
Sbjct: 134 FNAGKIRRQISCATISKPLLLS--NTSSEDLFNPKNNDKKETYARITLQKLFHEINNDEC 191
Query: 204 DLAIFDATNSTLQRRNYVLQEIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXX 263
D+ IFDATNST++RR ++ +E+ SFN +
Sbjct: 192 DVGIFDATNSTIERRRFIFEEVCSFNTDE------------------------------- 220
Query: 264 XXXXIHITPIFLQVSCTDPNFIKYNIHNKTFNQDYYDKPYEFAVKDFAKRLQQYHSQFVQ 323
++ PI LQVSC + +FIKYNIHNK+FN+DY DKPYE A+KDFAKRL+ Y+SQF
Sbjct: 221 -LSSFNLVPIILQVSCFNRSFIKYNIHNKSFNEDYLDKPYELAIKDFAKRLKHYYSQFTP 279
Query: 324 FSRSEFD---HYCKENARVNEGSHNPNFGLFFFHIMNAGQFSADDSNMYYFPSQYCSDTA 380
FS EF+ Y ++ ++ LFFF+++NAG N ++PS
Sbjct: 280 FSLDEFNQIHRYISQHEEIDT-------SLFFFNVINAGVVEPHSLNQSHYPSTCGKQIR 332
Query: 381 ELINTMEYFMENYSKMYGYGYIEKANEFLK 410
+ I +E F+ +YS+M+G+ YIE F +
Sbjct: 333 DTIMVIENFINHYSQMFGFEYIEAVKLFFE 362
>YIL107c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 827
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/238 (27%), Positives = 100/238 (41%), Gaps = 53/238 (22%)
Query: 100 RQNLNHKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRRQV 159
+++ K ++++GLPATGKS I+ L FL+ S C +FN GN RRK +
Sbjct: 177 KEDSGSKLVIVMVGLPATGKSFITNKLSRFLNYSL----YYCKVFNVGNTRRKFAKEHG- 231
Query: 160 SPFMAPELNKSEEDVFNPKNSHK---KEEYARIALSKLLNDLKQDRCDLAIFDATNSTLQ 216
L + F PKN+ ++++A L +LL+ L + + IFDATN++ +
Sbjct: 232 -------LKDQDSKFFEPKNADSTRLRDKWAMDTLDELLDYLLEGSGSVGIFDATNTSRE 284
Query: 217 RRNYVLQEIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITPIFLQ 276
RR VL IR + H+ +FL+
Sbjct: 285 RRKNVLARIRKRSP--------------------------------------HLKVLFLE 306
Query: 277 VSCTDPNFIKYNIHNKTFNQDYYDKPYEFAVKDFAKRLQQYHSQFVQFSRSEFDHYCK 334
C+D ++ NI K F DY K E ++KDF RL Y + E Y K
Sbjct: 307 SVCSDHALVQKNIRLKLFGPDYKGKDPESSLKDFKSRLANYLKAYEPIEDDENLQYIK 364
>YJL155c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 452
Score = 63.9 bits (154), Expect = 5e-10
Identities = 46/127 (36%), Positives = 67/127 (52%), Gaps = 13/127 (10%)
Query: 106 KFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRRQVSPFMAP 165
K CVI++GLPA GKS IS+ +I +L S ++ FN GN RR +S P A
Sbjct: 13 KVCVIMVGLPARGKSFISQKIIRYL----SWLSIKAKCFNVGNYRRDVSGN---VPMDAE 65
Query: 166 ELNKSEEDVFNPKNSHKKEEYARIALSKLLNDLKQDRCDLAIFDATNSTLQRRNYVLQEI 225
N D N +E A+ A+ ++N ++ +A+FDATNST +RR + L++I
Sbjct: 66 FFNFENTD-----NFKLRELAAQNAIKDIVNFFTKEDGSVAVFDATNSTRKRRKW-LKDI 119
Query: 226 RSFNKAQ 232
N Q
Sbjct: 120 CEKNNIQ 126
>Hs4505745 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 471
Score = 59.3 bits (142), Expect = 1e-08
Identities = 55/222 (24%), Positives = 88/222 (38%), Gaps = 55/222 (24%)
Query: 101 QNLNHKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRRQVS 160
Q N VI++GLPA GK+ IS L +L+ + +FN G RR+ + +
Sbjct: 37 QFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPT----KVFNLGQYRREAVSYKNYE 92
Query: 161 PFMAPELNKSEEDVFNPKNSHKKEEYARIALSKLLNDLKQDRCDLAIFDATNSTLQRRNY 220
F P+ N + +++ A AL + N L + +A+FDATN+T +RR+
Sbjct: 93 -FFLPD---------NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSL 142
Query: 221 VLQEIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITPIFLQVSCT 280
+LQ + + F++ C
Sbjct: 143 ILQFAKEHGYKVF----------------------------------------FIESICN 162
Query: 281 DPNFIKYNIHN-KTFNQDYYDKPYEFAVKDFAKRLQQYHSQF 321
DP I NI K + DY D E ++DF KR++ Y +
Sbjct: 163 DPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNY 204
>CE29606 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 435
Score = 59.3 bits (142), Expect = 1e-08
Identities = 54/232 (23%), Positives = 90/232 (38%), Gaps = 61/232 (26%)
Query: 98 NKRQNLNHKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRR 157
N + + + L+GLPA GK+ IS L +L+ ++ FN G RR+
Sbjct: 27 NSNEQVRVPNVIALVGLPARGKTYISHKLCRYLN----WIGIKTKAFNVGEYRRRACNLE 82
Query: 158 QVSPFMAPELNKSEEDVFNPKNSHK---KEEYARIALSKLLNDLKQDRCDLAIFDATNST 214
+ + E + F+P N+ ++E A++A+ + L ++AI DATN+T
Sbjct: 83 E----------EGENEFFSPNNARGQKIRDECAKLAIEDMGRYLDNKEGEVAILDATNTT 132
Query: 215 LQRRNYVLQEIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITP-- 272
RR +++ R+ +H P
Sbjct: 133 RDRRKLLMEFCRNM---------------------------------------MHEPPFR 153
Query: 273 -IFLQVSCTDPNFIKYNIHNKTFNQDYYD--KPYEFAVKDFAKRLQQYHSQF 321
F++ C DP+ I NI N Y E A +DF KR++ Y Q+
Sbjct: 154 VFFVESVCDDPDIINSNITEVKINSPDYKGIMSQEEAKEDFLKRIENYRMQY 205
>CE23252 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 456
Score = 59.3 bits (142), Expect = 1e-08
Identities = 54/232 (23%), Positives = 90/232 (38%), Gaps = 61/232 (26%)
Query: 98 NKRQNLNHKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRR 157
N + + + L+GLPA GK+ IS L +L+ ++ FN G RR+
Sbjct: 27 NSNEQVRVPNVIALVGLPARGKTYISHKLCRYLN----WIGIKTKAFNVGEYRRRACNLE 82
Query: 158 QVSPFMAPELNKSEEDVFNPKNSHK---KEEYARIALSKLLNDLKQDRCDLAIFDATNST 214
+ + E + F+P N+ ++E A++A+ + L ++AI DATN+T
Sbjct: 83 E----------EGENEFFSPNNARGQKIRDECAKLAIEDMGRYLDNKEGEVAILDATNTT 132
Query: 215 LQRRNYVLQEIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITP-- 272
RR +++ R+ +H P
Sbjct: 133 RDRRKLLMEFCRNM---------------------------------------MHEPPFR 153
Query: 273 -IFLQVSCTDPNFIKYNIHNKTFNQDYYD--KPYEFAVKDFAKRLQQYHSQF 321
F++ C DP+ I NI N Y E A +DF KR++ Y Q+
Sbjct: 154 VFFVESVCDDPDIINSNITEVKINSPDYKGIMSQEEAKEDFLKRIENYRMQY 205
>CE04687 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 450
Score = 57.8 bits (138), Expect = 3e-08
Identities = 55/225 (24%), Positives = 87/225 (38%), Gaps = 56/225 (24%)
Query: 109 VILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRRQVSPFMAPELN 168
++++GLPA GK+ IS+ L +L + T +FN G RR + A ++
Sbjct: 25 IVMVGLPARGKTYISKKLCRYLKWTGFTT----KVFNVGEYRRSDANA-------ADAIH 73
Query: 169 KSEEDVFNPKNSHK---KEEYARIALSKLLNDLKQDRCDLAIFDATNSTLQRRNYVLQEI 225
+ F+P N+ + E AR A+ + + L +AIFDATN+T RR ++
Sbjct: 74 GANASFFSPNNADALKVRAESARRAMEDMADYLNSGTGGVAIFDATNTTKDRRRIII--- 130
Query: 226 RSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITPIFLQVSCTDPNFI 285
F K Q + F++ C DP I
Sbjct: 131 -DFCKKQ------------------------------------RLRCFFIESVCDDPAII 153
Query: 286 KYNIHNKTFNQDYYD--KPYEFAVKDFAKRLQQYHSQFVQFSRSE 328
N+ + N Y E A +DF R++ Y Q+ SE
Sbjct: 154 DCNVTDVKVNSPDYKGLMTAEQAKEDFMNRIENYKKQYEPLDESE 198
>SPAC222.13c [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 592
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/226 (24%), Positives = 85/226 (36%), Gaps = 54/226 (23%)
Query: 98 NKRQNLNHKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRK--LST 155
N + K +IL+G+PATGKS I L + + + C F+ G+ RR+ ST
Sbjct: 135 NASYGIREKLIIILVGIPATGKSYIGSKLSRYYNWLK----YNCRFFSVGDKRREEGAST 190
Query: 156 RRQVSPFMAPELNKSEEDVFNPKNSHKKEEYARIALSKLLNDLKQDRCDLAIFDATNSTL 215
+ F D+ N + +E A L LL+ + + + I DATNST
Sbjct: 191 YSMSADFF---------DIKNEETFKFRENVALETLEDLLHWMIHENGVIGILDATNSTH 241
Query: 216 QRRNYVLQEIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITPIFL 275
+RR ++ YD+ I +FL
Sbjct: 242 ERRKHL-----------YDR----------------------------ISKEADIGIMFL 262
Query: 276 QVSCTDPNFIKYNIHNKTFNQDYYDKPYEFAVKDFAKRLQQYHSQF 321
+ CTD + NI K DY E A+KD +R+ Y +
Sbjct: 263 ESLCTDDILFEENIKLKIKGPDYEGYDTESALKDLRERVDLYKKYY 308
>Hs4758900 [G] KOG0234 Fructose-6-phosphate 2-kinase/fructose-26-biphosphatase
Length = 520
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/219 (23%), Positives = 87/219 (38%), Gaps = 54/219 (24%)
Query: 104 NHKFCVILIGLPATGKSTISRHLINFLHSSRSTAHLRCSIFNAGNVRRKLSTRRQVSPFM 163
N ++++GLPA GK+ IS+ L +L+ + +FN G RR+ + F
Sbjct: 33 NSPTVIVMVGLPARGKTYISKKLTRYLN----WIGVPTKVFNVGEYRREAVKQYSSYNFF 88
Query: 164 APELNKSEEDVFNPKNSHKKEEYARIALSKLLNDLKQDRCDLAIFDATNSTLQRRNYVLQ 223
P+ N + +++ A AL + + L ++ +A+FDATN+T +RR+ +L
Sbjct: 89 RPD---------NEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILH 139
Query: 224 EIRSFNKAQYDKHXXXXXXXXXXXXGXXXXXXXXXXXXXXXXXXIHITPIFLQVSCTDPN 283
F K K F++ C DP
Sbjct: 140 ----FAKENDFK------------------------------------AFFIESVCDDPT 159
Query: 284 FIKYNIHN-KTFNQDYYDKPYEFAVKDFAKRLQQYHSQF 321
+ NI K + DY D A+ DF KR+ Y + +
Sbjct: 160 VVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASY 198
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,796,420
Number of Sequences: 60738
Number of extensions: 829400
Number of successful extensions: 2429
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2411
Number of HSP's gapped (non-prelim): 16
length of query: 455
length of database: 30,389,216
effective HSP length: 110
effective length of query: 345
effective length of database: 23,708,036
effective search space: 8179272420
effective search space used: 8179272420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)