ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1843 good O KOG2930 Posttranslational modification, protein turnover, chaperones SCF ubiquitin ligase, Rbx1 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1843 651474 651803 110
(110 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL133w [O] KOG2930 SCF ubiquitin ligase Rbx1 component 168 1e-42
CE06614 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 139 8e-34
SPAC23H4.18c [O] KOG2930 SCF ubiquitin ligase Rbx1 component 138 1e-33
Hs7657508 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 138 1e-33
7290070 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 134 2e-32
7291966 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 130 4e-31
At3g42830 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 128 1e-30
ECU01g1095 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 118 2e-27
CE12670 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 113 5e-26
Hs7657522 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 112 6e-26
Hs18777675 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11 70 4e-13
7297435 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11 70 4e-13
At5g20570 [O] KOG2930 SCF ubiquitin ligase Rbx1 component 70 6e-13
SPAC343.03 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11 61 2e-10
CE00978 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11 51 2e-07
At3g05870 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11 51 3e-07
At5g42940 [O] KOG0800 FOG: Predicted E3 ubiquitin ligase 48 2e-06
At1g45180 [O] KOG0800 FOG: Predicted E3 ubiquitin ligase 47 3e-06
>YOL133w [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 121
Score = 168 bits (426), Expect = 1e-42
Identities = 71/103 (68%), Positives = 84/103 (80%), Gaps = 2/103 (1%)
Query: 10 AQSGTEGAT--ESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSE 67
AQS + A K FEI KWTAVAFWSWDI VDNCAICRNHIMEPC+ CQ +A +++
Sbjct: 19 AQSSNQSAPVETKKKRFEIKKWTAVAFWSWDIAVDNCAICRNHIMEPCIECQPKAMTDTD 78
Query: 68 HECVAAWGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCGK 110
+ECVAAWG CNHAFHLHCI +WIK+R+ CPLDN+PW+LARCG+
Sbjct: 79 NECVAAWGVCNHAFHLHCINKWIKTRDACPLDNQPWQLARCGR 121
>CE06614 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 110
Score = 139 bits (349), Expect = 8e-34
Identities = 56/108 (51%), Positives = 72/108 (65%), Gaps = 2/108 (1%)
Query: 2 ATDLGPIEAQSGTEGATESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQE 61
A+D +E + T K FE+ KW+AVA W+WDI VDNCAICRNHIM+ C+ CQ
Sbjct: 4 ASDSTAMEVEEATNQTV--KKRFEVKKWSAVALWAWDIQVDNCAICRNHIMDLCIECQAN 61
Query: 62 ATFNSEHECVAAWGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCG 109
+ EC AWG CNHAFH HCI++W+K+R VCPLDN+ W+ + G
Sbjct: 62 QAAGLKDECTVAWGNCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 109
>SPAC23H4.18c [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 107
Score = 138 bits (348), Expect = 1e-33
Identities = 54/91 (59%), Positives = 64/91 (69%)
Query: 19 ESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAAWGECN 78
+ P FEI KW AVA W WDI VDNCAICRNHIM+ C+ CQ + EC AWG CN
Sbjct: 16 QKPPRFEIKKWNAVALWQWDIVVDNCAICRNHIMDLCIECQANTDSAAAQECTVAWGTCN 75
Query: 79 HAFHLHCITQWIKSRNVCPLDNKPWKLARCG 109
HAFH HCI++W+ +RNVCPLDN+ W+ R G
Sbjct: 76 HAFHFHCISRWLNTRNVCPLDNREWEFQRYG 106
>Hs7657508 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 108
Score = 138 bits (347), Expect = 1e-33
Identities = 55/102 (53%), Positives = 69/102 (66%), Gaps = 1/102 (0%)
Query: 8 IEAQSGTEGATESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSE 67
++ SGT K FE+ KW AVA W+WDI VDNCAICRNHIM+ C+ CQ +
Sbjct: 7 VDTPSGTNSGA-GKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATS 65
Query: 68 HECVAAWGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCG 109
EC AWG CNHAFH HCI++W+K+R VCPLDN+ W+ + G
Sbjct: 66 EECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYG 107
>7290070 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 108
Score = 134 bits (338), Expect = 2e-32
Identities = 52/89 (58%), Positives = 63/89 (70%)
Query: 21 KPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAAWGECNHA 80
K FE+ KW AVA W+WDI VDNCAICRNHIM+ C+ CQ + EC AWG CNHA
Sbjct: 19 KKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHA 78
Query: 81 FHLHCITQWIKSRNVCPLDNKPWKLARCG 109
FH HCI++W+K+R VCPLDN+ W + G
Sbjct: 79 FHFHCISRWLKTRQVCPLDNREWDFQKYG 107
>7291966 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 122
Score = 130 bits (326), Expect = 4e-31
Identities = 55/103 (53%), Positives = 69/103 (66%), Gaps = 2/103 (1%)
Query: 9 EAQSGTEGATESKPN-FEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSE 67
E S + GA +++ F + KW A A W WD+ VDNCAICRNHIM C+ CQ + N +
Sbjct: 21 EEPSCSGGAVQARTERFVVKKWVAHAMWGWDVAVDNCAICRNHIMNLCIECQADPNANQD 80
Query: 68 HECVAAWGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCGK 110
EC AWGECNHAFH HCI +W+K+R VCPLDNK W + G+
Sbjct: 81 -ECTVAWGECNHAFHYHCIARWLKTRLVCPLDNKEWVYQKYGR 122
>At3g42830 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 115
Score = 128 bits (321), Expect = 1e-30
Identities = 51/105 (48%), Positives = 69/105 (65%)
Query: 5 LGPIEAQSGTEGATESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATF 64
+G + S ++++ FE+ KW+AVA W+WDI VDNCAICRNHIM+ C+ C
Sbjct: 10 MGESSSISVPSSSSKNSKRFELKKWSAVALWAWDIVVDNCAICRNHIMDLCIECLANQAS 69
Query: 65 NSEHECVAAWGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCG 109
+ EC AWG CNHAFH HCI++W+K+R VCPLD W+ + G
Sbjct: 70 ATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDVCEWEFQKYG 114
>ECU01g1095 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 92
Score = 118 bits (295), Expect = 2e-27
Identities = 48/85 (56%), Positives = 59/85 (68%), Gaps = 2/85 (2%)
Query: 19 ESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAAWGECN 78
E+K ++ KW VA WS D+ ++ CAICRNHIM+ CV CQ T N E C +WG CN
Sbjct: 2 ENKEIIKLKKWNLVALWSLDMKIETCAICRNHIMDTCVECQNGMTNNGE--CKVSWGVCN 59
Query: 79 HAFHLHCITQWIKSRNVCPLDNKPW 103
HAFH HCIT+W+ S+NVCPLD K W
Sbjct: 60 HAFHTHCITRWLSSKNVCPLDTKKW 84
>CE12670 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 112
Score = 113 bits (282), Expect = 5e-26
Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 5/97 (5%)
Query: 14 TEGATESKPNFEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAA 73
T +ES+P F + KW A+A W+WD++ D CAICR H+ME C+ CQ E + EC
Sbjct: 21 TANPSESRP-FVLKKWNALAVWAWDVECDTCAICRVHLMEECLRCQSEPS----AECYVV 75
Query: 74 WGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCGK 110
WG+CNH+FH C+TQWI+ N CPL K W ++R K
Sbjct: 76 WGDCNHSFHHCCMTQWIRQNNRCPLCQKDWVVSRTSK 112
>Hs7657522 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 113
Score = 112 bits (281), Expect = 6e-26
Identities = 46/104 (44%), Positives = 64/104 (61%), Gaps = 4/104 (3%)
Query: 8 IEAQSGTEGATESKPN-FEITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNS 66
+ + SG+ G+ F + KW AVA WSWD++ D CAICR +M+ C+ CQ E N
Sbjct: 13 LASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAE---NK 69
Query: 67 EHECVAAWGECNHAFHLHCITQWIKSRNVCPLDNKPWKLARCGK 110
+ +CV WGECNH+FH C++ W+K N CPL + W + R GK
Sbjct: 70 QEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK 113
>Hs18777675 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11
Length = 84
Score = 70.5 bits (171), Expect = 4e-13
Identities = 29/83 (34%), Positives = 44/83 (52%), Gaps = 8/83 (9%)
Query: 25 EITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAAWGECNHAFHLH 84
+I W VA W W + +NC ICR C +C+ +C WG+C+H FH+H
Sbjct: 4 KIKCWNGVATWLWVANDENCGICRMAFNGCCPDCKVPGD-----DCPLVWGQCSHCFHMH 58
Query: 85 CITQWIKSRNV---CPLDNKPWK 104
CI +W+ ++ V CP+ + WK
Sbjct: 59 CILKWLHAQQVQQHCPMCRQEWK 81
>7297435 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11
Length = 447
Score = 70.5 bits (171), Expect = 4e-13
Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 26 ITKWTAVAFWSWDIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAAWGECNHAFHLHC 85
I WT VA W W + +NC ICR C C +C WG C+H FH+HC
Sbjct: 5 IKSWTGVATWRWIANDENCGICRMSFESTCPECALPGD-----DCPLVWGVCSHCFHMHC 59
Query: 86 ITQWIKSRNV---CPLDNKPWK 104
I +W+ + + CP+ + WK
Sbjct: 60 IVKWLNLQPLNKQCPMCRQSWK 81
>At5g20570 [O] KOG2930 SCF ubiquitin ligase Rbx1 component
Length = 120
Score = 69.7 bits (169), Expect = 6e-13
Identities = 35/88 (39%), Positives = 44/88 (49%), Gaps = 20/88 (22%)
Query: 9 EAQSGTEGATESKP--NFEITKWTAVAFWSWD------------------IDVDNCAICR 48
EA S ++ +K FEI KW+AVA W+W I VDNCAICR
Sbjct: 15 EASSSVAASSSNKKAKRFEIKKWSAVALWAWGNLENPYTLSSIGLSMFRYIVVDNCAICR 74
Query: 49 NHIMEPCVNCQQEATFNSEHECVAAWGE 76
NHIM+ C+ CQ + EC AWG+
Sbjct: 75 NHIMDLCIECQANQASATSEECTVAWGK 102
>SPAC343.03 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11
Length = 94
Score = 61.2 bits (147), Expect = 2e-10
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 25 EITKWTAVAFWSWDIDVDN-CAICRNHIMEPCVNCQQEATFNSEHECVAAWGECNHAFHL 83
+I ++ A+A W+WD D+ C ICR C C C WG+C H FH
Sbjct: 4 KILRYHAIANWTWDTPKDDVCGICRVPFDGCCPQCTSPGD-----NCPIVWGKCKHIFHA 58
Query: 84 HCITQWIK---SRNVCPLDNKPWKLA 106
HCI W+ S+ CP+D + + +A
Sbjct: 59 HCIQNWLATSGSQGQCPMDRQTFVVA 84
>CE00978 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11
Length = 135
Score = 51.2 bits (121), Expect = 2e-07
Identities = 28/94 (29%), Positives = 38/94 (39%), Gaps = 11/94 (11%)
Query: 18 TESKPNFEITKWTAVAFWSW-DIDVDNCAICRNHIMEPCVNCQQEATFNSEHECVAAWGE 76
T ++ + + K W W D C ICR C C+ +C G
Sbjct: 45 TNTRMSITVKKLHVCGEWKWLQGGEDTCGICRMEFESACNMCKFPGD-----DCPLVLGI 99
Query: 77 CNHAFHLHCITQWI-----KSRNVCPLDNKPWKL 105
C HAFH HCI +WI + R CPL + W +
Sbjct: 100 CRHAFHRHCIDKWIAAPTNQPRAQCPLCRQDWTI 133
>At3g05870 [DO] KOG1493 Anaphase-promoting complex (APC) subunit 11
Length = 57
Score = 50.8 bits (120), Expect = 3e-07
Identities = 18/39 (46%), Positives = 25/39 (63%), Gaps = 3/39 (7%)
Query: 69 ECVAAWGECNHAFHLHCITQWIKSRNV---CPLDNKPWK 104
+C WG CNHAFHLHCI +W+ S+ CP+ + W+
Sbjct: 16 DCPLIWGACNHAFHLHCILKWVNSQTSQAHCPMCRREWQ 54
>At5g42940 [O] KOG0800 FOG: Predicted E3 ubiquitin ligase
Length = 691
Score = 48.1 bits (113), Expect = 2e-06
Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 4/46 (8%)
Query: 53 EPCVNCQQEATFNSEHECVAAWGECNHAFHLHCITQWIKSRNVCPL 98
EPC CQ+E T + + EC H FH CI +W+K +N+CP+
Sbjct: 635 EPCCVCQEEYTEGEDMGTL----ECGHEFHSQCIKEWLKQKNLCPI 676
>At1g45180 [O] KOG0800 FOG: Predicted E3 ubiquitin ligase
Length = 645
Score = 47.4 bits (111), Expect = 3e-06
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 4/47 (8%)
Query: 52 MEPCVNCQQEATFNSEHECVAAWGECNHAFHLHCITQWIKSRNVCPL 98
+EPC CQ+E + E E EC H FH CI +W+K +N+CP+
Sbjct: 589 VEPCCVCQEE--YKEEEEIGRL--ECGHDFHSQCIKEWLKQKNLCPI 631
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.133 0.476
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,628,571
Number of Sequences: 60738
Number of extensions: 302159
Number of successful extensions: 1178
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1156
Number of HSP's gapped (non-prelim): 19
length of query: 110
length of database: 30,389,216
effective HSP length: 86
effective length of query: 24
effective length of database: 25,165,748
effective search space: 603977952
effective search space used: 603977952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)