ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1892 good J KOG2409 Translation, ribosomal structure and biogenesis KRR1-interacting protein involved in 40S ribosome biogenesis
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1892 670967 669204 -588
(588 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL308c [J] KOG2409 KRR1-interacting protein involved in 40S rib... 500 e-141
SPAC22G7.05 [J] KOG2409 KRR1-interacting protein involved in 40S... 161 3e-39
7294617 [J] KOG2409 KRR1-interacting protein involved in 40S rib... 92 2e-18
At3g24080 [J] KOG2409 KRR1-interacting protein involved in 40S r... 83 1e-15
Hs12711672 [J] KOG2409 KRR1-interacting protein involved in 40S ... 78 4e-14
>YNL308c [J] KOG2409 KRR1-interacting protein involved in 40S ribosome
biogenesis
Length = 591
Score = 500 bits (1287), Expect = e-141
Identities = 271/535 (50%), Positives = 341/535 (63%), Gaps = 14/535 (2%)
Query: 30 VPTTDVEGKNTEVISVKTGSKHDVTASKE-VPAEVXXXXXXXXXXXXXXXYGELITEEVE 88
VP TD T S T K + ASK VP+E YGELIT+EVE
Sbjct: 21 VPATDTATIKTSETSATT-VKPAIEASKSYVPSE--DEEEDEEEEEEEDDYGELITDEVE 77
Query: 89 EGIQKVLDAIKNNETDKLLNPGVKFFEEPEKAVEKLAKTE-KHKPVYLKDYHRMNLLNGN 147
GI +VLDAIKNN+TDKLL+P VKFFE+PE A KLA E KHKP+YLKDYHRMN+L+G+
Sbjct: 78 NGINQVLDAIKNNKTDKLLDPKVKFFEDPESAAAKLANREGKHKPIYLKDYHRMNILSGD 137
Query: 148 VNADDDEDLEFETVDGKQSFASHQREERNQLLSEIKDAFNXXXXXXXXXXXXXXFLKKKE 207
+DDE+ E TVDGKQSF S QREE+ QLL+EIK AF+ FLKKKE
Sbjct: 138 ALKEDDEEYEHATVDGKQSFVSQQREEKTQLLNEIKSAFSDEENEESSGDEDDGFLKKKE 197
Query: 208 PQNKRESEVKLPNPKVDDEKFLEEFVNQQAWIPKKGDKVINLDRRGTDIEEDEDFDDAVE 267
P K+E + LP+P V++E FLEEFVNQQAWIPKKGDKVI+LD + E+DE+F+DA E
Sbjct: 198 PSTKKEGK-NLPDPTVNEENFLEEFVNQQAWIPKKGDKVISLDLNNNE-EDDEEFEDAAE 255
Query: 268 QFENAYNFRYEDPNAAEIVSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 327
+FENAYNFRYEDPNAAEI+SY
Sbjct: 256 KFENAYNFRYEDPNAAEIISYARSQATLRRSDDSSRRRKREEKRKIKEQIKAEKETALQK 315
Query: 328 XXXXXXNQLTDVLEQVKKEYGADIKEEHVKALTDTLINGNFEDGKWDEVIGTIFNDEFYN 387
N+LTD+LEQ+ KEYGA+I + VK +TDTL+ +F++ +WD V+ +FN+EFY
Sbjct: 316 KKTKKLNKLTDILEQLTKEYGAEINADMVKKITDTLLKNDFKEEEWDNVVAELFNEEFYQ 375
Query: 388 QEDKPTWDENDDIMGEFYAEQETEDHAEDDETLAS--DSGEPXXXXXXXXXXXXXXXXXX 445
QE KPTW+E+D+IMG+FYA+ + +D E+ E + E
Sbjct: 376 QEGKPTWNEDDEIMGDFYADADGDDQTEEGEVEKEQKEEDEEEGPKRKKSKKEEKLQKKK 435
Query: 446 XXXQLHEMVEKAVDERKVDIIEQVEEE----RGRS-TEKNSEVKFRYREVSPESFGLTTR 500
+++E+VE A+++ K+ +IE+VE+E + RS T++ ++KFRYREVSPESFGLT R
Sbjct: 436 EKRKVNELVENALEQNKLALIEEVEKEEEERKSRSRTKEEQDLKFRYREVSPESFGLTAR 495
Query: 501 EIFTADDADLNEFIGLKKFAPYRPKELTSKDRRKVTKSRRLREWRKKVFNTEEGL 555
EIF ADD DLNEFIGLKKFAPYR KEL +KD+RKV K+RRLREWRKK F E GL
Sbjct: 496 EIFAADDTDLNEFIGLKKFAPYRSKELRAKDKRKVMKARRLREWRKKTFKNENGL 550
>SPAC22G7.05 [J] KOG2409 KRR1-interacting protein involved in 40S ribosome
biogenesis
Length = 598
Score = 161 bits (407), Expect = 3e-39
Identities = 135/518 (26%), Positives = 220/518 (42%), Gaps = 80/518 (15%)
Query: 80 GELITEEVEEGIQKVLDAIKNNETDKLLNPGVKFFEEPEKAVE-KLAKTEKHKPVYLKDY 138
GEL+T EV+ I +++ I+N + D L + K+F+E EK V+ L + + V LKDY
Sbjct: 111 GELVTPEVDAAILRMIVKIRNKDPD-LYDSQQKYFDEVEKDVQGSLKSKDGFRSVTLKDY 169
Query: 139 HRMNLLNGNV-NADDDEDLEFETVDGKQSFASHQREERNQLLSEIKDAFNXXXXXXXXXX 197
HR LL+G + +A++DE + D + Q R + ++ D
Sbjct: 170 HRQKLLSGEILDAEEDEPMPN---DANPTHVEEQERLRKETIAAFHDVNGNKDAVSNESD 226
Query: 198 XXXXFLKKKEPQNKRESEVK----------------------------------LPNPKV 223
FL KKE K+ E + L N +
Sbjct: 227 EDGDFLVKKEKTKKQLEEEEHGYERFLLESAQSKEARKVLEDLSSSYVKQRPSVLVNTED 286
Query: 224 D-------DEKFLEEFVNQQAWIPKKGDKVINLDRRGTDIEEDEDFDDAVEQFENAYNFR 276
D DE FL +++ + W K + + +++ + FD+ E+FEN +NFR
Sbjct: 287 DENGIKPSDEDFLLKYMMNRGW-RTSNTKQPSYEEIIDEVDAENRFDEDAEEFENKFNFR 345
Query: 277 YEDPNAAEIVSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNQL 336
+E+ ++IVS+ +L
Sbjct: 346 FEEEAGSQIVSHPRNVADSLRRKDDSRKRARDRKKERLEEASQKRLEEVNRLKNLKRKEL 405
Query: 337 TDVLEQVKKEYGADIKEEHVKALTDTLINGNFEDGKWDEVIGTIFNDEFYNQED--KPTW 394
+ L QV + G+ K V L ++ +F+ KW+ + IFN+ +Y ++ KP +
Sbjct: 406 EEKLNQVIEIAGS--KNIDVSKLD---LDEDFDPEKWESKMSEIFNENYYEEDSAKKPEF 460
Query: 395 DENDDIMGEFYAEQETEDHAEDDETLASDSGEPXXXXXXXXXXXXXXXXXXXXXQLHEMV 454
++ DI + +ED + D+G + + +
Sbjct: 461 GDDIDIDDIAQVDNGSEDLGSIENKTVEDTGN--------------------REKSKKSL 500
Query: 455 EKAVDERKVDIIEQVEEERGRSTE---KNSEVKFRYREVSPESFGLTTREIFTADDADLN 511
K + E+K I E VEE+ G KNS KFRY++V+PE+FGL +I A DADLN
Sbjct: 501 RKDIREKKRKIDEYVEEKYGVPEAVIVKNS--KFRYQQVAPETFGLDILDILNASDADLN 558
Query: 512 EFIGLKKFAPYRPKELTSKDRRKVTKSRRLREWRKKVF 549
++GLKK PYR E ++D++K K +RLREW+K+VF
Sbjct: 559 NYVGLKKMTPYRTPEEIARDKKKYGKKKRLREWKKQVF 596
>7294617 [J] KOG2409 KRR1-interacting protein involved in 40S ribosome
biogenesis
Length = 855
Score = 92.0 bits (227), Expect = 2e-18
Identities = 113/550 (20%), Positives = 197/550 (35%), Gaps = 74/550 (13%)
Query: 83 ITEEVEEGIQKVLDAIKNNETDKLLNPGVKFF-----EEPEKAVEKLAKTEKHKPVYLKD 137
+ + ++ K L ++K+ + + + G KFF +E +K E K +K KPV LKD
Sbjct: 64 VDPKFDQDFFKTLSSLKSKDPC-IYDKGTKFFSESSGDEDDKDGEAPKKKKKAKPVTLKD 122
Query: 138 YHRMNLL--NGNVNADDDEDLEFETVDGKQSFASHQREERNQLLSEIKDAFNXXXXXXXX 195
Y R +L NG + D+E E E + +++ + EE +L +E + N
Sbjct: 123 YERKVILEHNGKFESSDEEQQEKEHEELQRAQSPSAVEEERRLKAEFRKVMNKEDDSEDE 182
Query: 196 XXXXXXFLKKKEPQNKRESEV--------KLPNPKVDDEKFLEEFVNQQAWIPKK----- 242
+ K + E K + D+K LE +Q W K
Sbjct: 183 EFGGIFKKRSKTKEQTAAEEADFAKWLAGKQAEIQETDKKQLEPL--KQYWSSNKLTQGE 240
Query: 243 ---GDKVINLDRRGTD----------------IEEDEDFDDAVEQFENAYNFRYEDPNAA 283
D ++N TD + EDE + +FE+ YNFR+E+P+A
Sbjct: 241 SFLRDYILNKGYANTDESAIPTYDEIVGEAAPLSEDEQELEKQAEFEHKYNFRFEEPDAD 300
Query: 284 EIVSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNQLTDVLEQV 343
I Y ++ + + ++
Sbjct: 301 FIKRYPRTIEQSLRRTDDKRKEKRKELKERKDQEKQQKMKELELVKEMKRKEIDEKIRKL 360
Query: 344 KKEYGADIKEEHVKALTDTLINGNFEDGKWDEVIGTIFNDEFYN---QEDKP-------- 392
K G D D + +F+ D + +F+DE+YN E+KP
Sbjct: 361 KAVTGND-----ELGFRDEELEEDFDPAAHDRRMQELFDDEYYNVDEGEEKPECPSDIDE 415
Query: 393 ----TWDENDDIMGEFYAEQETEDHAEDDETLASDSGEPXXX-----XXXXXXXXXXXXX 443
WD D ++ E H EDD+ +P
Sbjct: 416 LVLEDWDNYDPRQHANGGGEDYEGHCEDDDFNMDCDYDPSTAKEQLQQELIENTRGRKGR 475
Query: 444 XXXXXQLHEMVE------KAVDERKV-DIIEQVEEERGRSTEKNSEVKFRYREVSPESFG 496
+ EM++ DE+ + I++ + + +F+Y E +P FG
Sbjct: 476 KGRRNRFMEMIQAEKPAFNPEDEKTYSEYIDEYYQMDCEDIIGDQPCRFKYVETTPNDFG 535
Query: 497 LTTREIFTADDADLNEFIGLKKFAPYRPKELTSKDRRKVTKSRRLREWRKKVFNTEEGLT 556
LT EI A + +LN++ LKK RP+ + K++R + + ++K+F + G
Sbjct: 536 LTIEEILLAKNKELNQWASLKKAVQNRPEHVEKKEQRLYKMKAKNEDLKRKIFKSLYGEG 595
Query: 557 GDELAIPLND 566
D+ P +
Sbjct: 596 SDDEEQPAEE 605
>At3g24080 [J] KOG2409 KRR1-interacting protein involved in 40S ribosome
biogenesis
Length = 637
Score = 82.8 bits (203), Expect = 1e-15
Identities = 103/484 (21%), Positives = 178/484 (36%), Gaps = 75/484 (15%)
Query: 115 EEPEKAVEKLAKTEKHKPVYLKDYHRMNLLNGNVN-ADDDEDLEFETVDGKQSFASHQRE 173
EE E + K +K K +YLKD +LL G ++DE+ + T +A Q+E
Sbjct: 108 EEDEVDKKDTKKKKKKKKMYLKDVQAQHLLEGGPEFVEEDEERKVRT------YAEEQKE 161
Query: 174 ERNQLLSEIKDAFNXXXXXXXXXXXXXXFLKKKEPQNKRESEVKLPNPKVDDE------- 226
R + K N FL+ E + + EV K DE
Sbjct: 162 TRKAVTDAWKAEGNESGEDDD-------FLRVVEKEGDDDVEVDEELAKKMDEYYGDEAE 214
Query: 227 ----KFLEEFVNQQAWIPKKGDKVINLDRRGTDIEEDEDFDDAVEQFE-----NAYNFRY 277
+FL++++ +Q W K+ ++ + + ++ ED+ E FE + N+R+
Sbjct: 215 ATENQFLKDYLVKQLW--KEKEERVPGEEELKELSEDDHEVWDQEDFEAGRPLDLLNYRH 272
Query: 278 EDPNAAEIVSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNQLT 337
ED NA + V +
Sbjct: 273 EDENAGDTVMGQSRVVEGSVRKKDNARKAQRKNKDERMKKEDDVRKEELKRLKNVKKK-- 330
Query: 338 DVLEQVKKEYG-ADIKEEHVKALTDTLINGNFEDGKWDEVIGTIFNDEFYNQEDKPTWDE 396
++ E++KK A K+ L + F+ ++D+++ F+D++Y +ED +
Sbjct: 331 EIKEKMKKVLSVAGFKDGEECPLDAKDFDDEFDPEEYDKMMKAAFDDKYYGEEDSDLNSD 390
Query: 397 NDDIMGEFYAEQETEDHAEDDETLASDS------GEPXXXXXXXXXXXXXXXXXXXXXQL 450
DD + E D ++DE L G +
Sbjct: 391 EDD-------DGEKPDFDKEDELLGLPKDWDVTKGGDVFAAAREKVLKHKENMLGIDEEE 443
Query: 451 HEMVEKAVDERKVDIIEQVEEERGRSTEKNSEV--------------------------K 484
E E+ DE + ++ E+ E E R ++ + + +
Sbjct: 444 EEDEEEEEDEEEEEVDEEKEAEGKRKRKRKTSLVQKTKEALMEEYYKLDYEDTIGELRTR 503
Query: 485 FRYREVSPESFGLTTREIFTADDADLNEFIGLKKFAPYRPKELTSKDRRKVTKSRRLRE- 543
F+Y +V P F L T EI T DDA+LN+++ LKK APY K+ + + R++RE
Sbjct: 504 FKYAKVQPNRFELDTGEILTLDDAELNQYVPLKKMAPYVEKDWEVNRHKVKEQKRKIREL 563
Query: 544 WRKK 547
W K
Sbjct: 564 WEGK 567
>Hs12711672 [J] KOG2409 KRR1-interacting protein involved in 40S ribosome
biogenesis
Length = 591
Score = 77.8 bits (190), Expect = 4e-14
Identities = 98/481 (20%), Positives = 187/481 (38%), Gaps = 75/481 (15%)
Query: 133 VYLKDYHRMNLLNGNVNADDDEDLEFETVDGK------QSFASHQREERNQLLSEIKDAF 186
+YLKDY R +L D+E+ + ET + + QS+ Q++ + + ++D+
Sbjct: 1 MYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSE 60
Query: 187 NXXXXXXXXXXXXXXFLKKKEPQNKRES----------EVKLPN--------------PK 222
+ K ++ + + E+ E++ P+ P+
Sbjct: 61 DEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPE 120
Query: 223 VDD-EKFLEEFV-------------NQQAWIPKKG--DKVINLDRRGTDIEEDEDFDDAV 266
+D+ E+FL +++ +++ +KG + L G+ +E E F
Sbjct: 121 LDEGERFLRDYILNKRYEEGEEEEEDEEEMEEEKGVHGPPVQLAVDGSS-DEGELFLKKQ 179
Query: 267 EQFENAYNFRYEDPNAAEIVSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 326
E FE YNFR+E+P++A + +Y
Sbjct: 180 EDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREETRERKKREKAKKQEELK 239
Query: 327 XXXXXXXNQLTDVLEQVKKEYGADIKEEHVKALTDTLINGNFEDGKWDEVIGTIFNDEFY 386
++ LE+++K G ++ L + + +F+ + D+++ F DE+Y
Sbjct: 240 QLKNLKRKEILAKLEKLRKVTGNEML-----GLEEGDLEDDFDPAQHDQLMQKCFGDEYY 294
Query: 387 N--QEDKPTWDENDDIMGEFY------AEQE-----TEDHAEDDETLAS---DSGEPXXX 430
+E+KP ++E + + ++ EQE E H ED D +P
Sbjct: 295 GAVEEEKPQFEEEEGLEDDWNWDTWDGPEQEGDWSQQELHCEDPNFNMDADYDPSQPRKK 354
Query: 431 XXXXXXXXXXXXXXXXXXQLHEMVEKAVDERKVDIIEQVEEERGRSTEKNS----EVKFR 486
+ + EK V E E+ +E R ++ +F+
Sbjct: 355 KREAPLTGKKKRKSPFAAAVGQ--EKPVFEPGDKTFEEYLDEYYRLDYEDIIDDLPCRFK 412
Query: 487 YREVSPESFGLTTREIFTADDADLNEFIGLKKFAPYRPKELTSKDRRKVTKSRRLREWRK 546
YR V P FGL+T EI ADD +LN + LKK YR ++ +D+R ++ + W+K
Sbjct: 413 YRTVVPCDFGLSTEEILAADDKELNRWCSLKKTCMYRSEQEELRDKRAYSQKAQ-NSWKK 471
Query: 547 K 547
+
Sbjct: 472 R 472
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.308 0.131 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,873,503
Number of Sequences: 60738
Number of extensions: 1279281
Number of successful extensions: 4350
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4328
Number of HSP's gapped (non-prelim): 13
length of query: 588
length of database: 30,389,216
effective HSP length: 112
effective length of query: 476
effective length of database: 23,586,560
effective search space: 11227202560
effective search space used: 11227202560
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)