ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1906 check: MH G KOG0658 Carbohydrate transport and metabolism Glycogen synthase kinase-3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1906 673787 672693 -365
(365 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL307c [G] KOG0658 Glycogen synthase kinase-3 587 e-168
YOL128c [G] KOG0658 Glycogen synthase kinase-3 308 8e-84
7290342 [G] KOG0658 Glycogen synthase kinase-3 277 2e-74
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 276 3e-74
CE21401 [G] KOG0658 Glycogen synthase kinase-3 268 1e-71
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 267 2e-71
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 267 2e-71
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 265 6e-71
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 263 2e-70
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 263 3e-70
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 261 9e-70
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 261 1e-69
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 258 7e-69
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 257 2e-68
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 257 2e-68
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 256 3e-68
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 256 4e-68
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 255 8e-68
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 254 2e-67
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 252 7e-67
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 238 8e-63
YDL079c [G] KOG0658 Glycogen synthase kinase-3 229 6e-60
YMR139w [G] KOG0658 Glycogen synthase kinase-3 226 3e-59
CE08727 [G] KOG0658 Glycogen synthase kinase-3 223 4e-58
7298004 [G] KOG0658 Glycogen synthase kinase-3 163 3e-40
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 162 6e-40
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 160 2e-39
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 160 4e-39
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 158 1e-38
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 157 2e-38
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 156 5e-38
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 155 7e-38
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 154 3e-37
7298087 [T] KOG0660 Mitogen-activated protein kinase 154 3e-37
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 153 4e-37
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 151 1e-36
YLR113w [T] KOG0660 Mitogen-activated protein kinase 151 2e-36
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 151 2e-36
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 151 2e-36
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 150 2e-36
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 150 2e-36
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 150 3e-36
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 150 3e-36
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 150 3e-36
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 150 3e-36
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 149 5e-36
7301110 [T] KOG0660 Mitogen-activated protein kinase 149 6e-36
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 149 8e-36
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 148 1e-35
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 148 1e-35
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 147 2e-35
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 147 2e-35
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 147 3e-35
YPR054w [T] KOG0660 Mitogen-activated protein kinase 145 1e-34
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 144 2e-34
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 144 2e-34
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 144 2e-34
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 144 2e-34
CE24971 [T] KOG0660 Mitogen-activated protein kinase 144 3e-34
CE01583 [T] KOG0660 Mitogen-activated protein kinase 144 3e-34
CE06686 [T] KOG0660 Mitogen-activated protein kinase 143 3e-34
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 143 3e-34
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 143 3e-34
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 142 6e-34
At1g18670 [D] KOG0600 Cdc2-related protein kinase 142 6e-34
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 142 8e-34
YBL016w [T] KOG0660 Mitogen-activated protein kinase 141 1e-33
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 141 2e-33
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 141 2e-33
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 140 3e-33
CE29020 [T] KOG0660 Mitogen-activated protein kinase 140 3e-33
At1g33770 [D] KOG0600 Cdc2-related protein kinase 140 4e-33
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 140 4e-33
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 139 5e-33
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 139 5e-33
YHR030c [T] KOG0660 Mitogen-activated protein kinase 139 7e-33
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 7e-33
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 9e-33
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 9e-33
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 139 9e-33
CE06762 [T] KOG0660 Mitogen-activated protein kinase 139 9e-33
At1g54610 [D] KOG0600 Cdc2-related protein kinase 139 9e-33
7291043 [T] KOG0660 Mitogen-activated protein kinase 138 1e-32
YPR161c [D] KOG0600 Cdc2-related protein kinase 137 2e-32
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 137 2e-32
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 137 2e-32
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 137 2e-32
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 137 3e-32
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 136 6e-32
YGR040w [T] KOG0660 Mitogen-activated protein kinase 135 7e-32
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 135 7e-32
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 135 7e-32
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 135 7e-32
CE09532 [G] KOG0658 Glycogen synthase kinase-3 135 9e-32
At4g10010 [D] KOG0600 Cdc2-related protein kinase 135 9e-32
At1g53050 [D] KOG0600 Cdc2-related protein kinase 135 9e-32
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 135 1e-31
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 134 2e-31
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 132 8e-31
At5g39420 [D] KOG0600 Cdc2-related protein kinase 132 8e-31
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 132 1e-30
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 132 1e-30
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 132 1e-30
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 1e-30
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 131 1e-30
CE05866 [G] KOG0658 Glycogen synthase kinase-3 131 1e-30
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 1e-30
At1g03740 [D] KOG0600 Cdc2-related protein kinase 131 1e-30
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 131 2e-30
CE20405 [G] KOG0658 Glycogen synthase kinase-3 131 2e-30
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 130 2e-30
At3g05050 [D] KOG0600 Cdc2-related protein kinase 130 2e-30
At1g74330 [D] KOG0600 Cdc2-related protein kinase 130 2e-30
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 130 2e-30
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 130 2e-30
At5g50860 [D] KOG0600 Cdc2-related protein kinase 130 3e-30
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 130 4e-30
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 130 4e-30
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 129 5e-30
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 129 5e-30
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 129 5e-30
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 129 5e-30
At5g44290 [D] KOG0600 Cdc2-related protein kinase 129 5e-30
At1g09600 [D] KOG0600 Cdc2-related protein kinase 129 5e-30
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 129 7e-30
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 129 9e-30
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 129 9e-30
At1g71530 [D] KOG0600 Cdc2-related protein kinase 129 9e-30
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 128 2e-29
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 128 2e-29
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 127 2e-29
CE05377 [G] KOG0658 Glycogen synthase kinase-3 127 2e-29
YKL139w [D] KOG0600 Cdc2-related protein kinase 127 3e-29
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 127 3e-29
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 127 3e-29
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 127 3e-29
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 127 3e-29
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 127 3e-29
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 126 4e-29
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 126 4e-29
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 126 6e-29
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 126 6e-29
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 6e-29
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 6e-29
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 125 7e-29
CE29318 [T] KOG0660 Mitogen-activated protein kinase 125 7e-29
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 125 7e-29
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 125 1e-28
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 125 1e-28
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 125 1e-28
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 124 2e-28
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 124 2e-28
CE27220 [T] KOG0660 Mitogen-activated protein kinase 124 2e-28
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 124 2e-28
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 124 2e-28
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 124 2e-28
YKL161c [T] KOG0660 Mitogen-activated protein kinase 123 5e-28
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 123 5e-28
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 122 6e-28
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 122 6e-28
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 122 8e-28
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 122 8e-28
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 122 8e-28
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 122 1e-27
CE17062 [T] KOG0660 Mitogen-activated protein kinase 121 2e-27
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 120 2e-27
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 120 3e-27
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 120 3e-27
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 120 3e-27
CE01612 [G] KOG0658 Glycogen synthase kinase-3 120 4e-27
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 119 5e-27
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 119 5e-27
At4g22940 [D] KOG0600 Cdc2-related protein kinase 119 9e-27
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 118 1e-26
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 118 1e-26
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 118 2e-26
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 117 2e-26
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 117 3e-26
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 117 3e-26
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 117 3e-26
At5g10270 [D] KOG0600 Cdc2-related protein kinase 117 3e-26
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 117 3e-26
At1g57700 [D] KOG0600 Cdc2-related protein kinase 117 3e-26
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 117 3e-26
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 116 5e-26
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 116 5e-26
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 116 5e-26
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 116 5e-26
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 116 5e-26
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 116 5e-26
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 5e-26
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 116 5e-26
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 116 6e-26
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 116 6e-26
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 115 1e-25
At5g64960 [D] KOG0600 Cdc2-related protein kinase 115 1e-25
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 114 2e-25
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 114 2e-25
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 114 2e-25
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 114 2e-25
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 114 3e-25
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 113 4e-25
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 113 4e-25
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 113 4e-25
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 113 4e-25
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 113 4e-25
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 113 5e-25
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 7e-25
CE26422 [D] KOG0600 Cdc2-related protein kinase 112 7e-25
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 112 9e-25
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 112 9e-25
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 112 1e-24
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 112 1e-24
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 111 1e-24
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 111 1e-24
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 111 1e-24
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 111 1e-24
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 111 1e-24
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 111 1e-24
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 110 2e-24
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 110 3e-24
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 110 3e-24
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 110 4e-24
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 109 7e-24
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 109 7e-24
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 108 1e-23
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 108 1e-23
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 108 1e-23
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 108 2e-23
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 107 3e-23
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 107 3e-23
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 107 3e-23
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 4e-23
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 106 5e-23
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 105 8e-23
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 105 1e-22
7296451 [D] KOG0600 Cdc2-related protein kinase 105 1e-22
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 105 1e-22
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 1e-22
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 105 1e-22
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 105 1e-22
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 104 2e-22
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 104 2e-22
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 104 2e-22
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 104 2e-22
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 104 2e-22
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 103 5e-22
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 102 7e-22
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 102 7e-22
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 102 7e-22
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 7e-22
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 102 9e-22
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 9e-22
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 102 1e-21
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 2e-21
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 101 2e-21
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 2e-21
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 101 2e-21
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 100 3e-21
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 3e-21
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 3e-21
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 3e-21
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 3e-21
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 100 6e-21
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 100 6e-21
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 99 7e-21
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 99 7e-21
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 99 1e-20
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 98 2e-20
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 97 5e-20
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 96 6e-20
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 96 8e-20
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 96 1e-19
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 95 1e-19
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 95 1e-19
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 95 1e-19
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 94 3e-19
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 94 3e-19
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 94 3e-19
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 94 4e-19
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 93 5e-19
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 93 5e-19
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 93 7e-19
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 92 9e-19
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 92 9e-19
7300559 [T] KOG4279 Serine/threonine protein kinase 92 9e-19
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 92 1e-18
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 92 1e-18
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 92 1e-18
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 92 2e-18
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 92 2e-18
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 2e-18
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 91 2e-18
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 91 3e-18
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 91 3e-18
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 90 5e-18
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 90 5e-18
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 90 5e-18
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 90 6e-18
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 90 6e-18
YKL101w [D] KOG0588 Serine/threonine protein kinase 89 1e-17
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 89 1e-17
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 89 1e-17
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 89 1e-17
CE01554 [T] KOG0986 G protein-coupled receptor kinase 89 1e-17
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 89 1e-17
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 89 1e-17
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 88 2e-17
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 88 2e-17
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 88 2e-17
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 88 2e-17
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 88 2e-17
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 88 2e-17
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 88 2e-17
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 87 3e-17
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 87 3e-17
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 87 4e-17
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 87 4e-17
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 87 4e-17
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 87 5e-17
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 5e-17
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 87 5e-17
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 86 7e-17
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 86 7e-17
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 7e-17
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 86 7e-17
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 86 9e-17
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 86 9e-17
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 86 9e-17
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 86 9e-17
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 86 9e-17
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 86 9e-17
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 86 1e-16
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 86 1e-16
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 86 1e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 85 1e-16
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 85 2e-16
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 85 2e-16
7301213 [R] KOG0589 Serine/threonine protein kinase 85 2e-16
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 85 2e-16
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 84 2e-16
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 84 2e-16
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 84 2e-16
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 84 3e-16
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 84 3e-16
7303211 [T] KOG4717 Serine/threonine protein kinase 84 3e-16
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 84 4e-16
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 84 4e-16
7299437 [R] KOG0586 Serine/threonine protein kinase 84 4e-16
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 83 6e-16
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 83 6e-16
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 83 6e-16
YDR507c [D] KOG0588 Serine/threonine protein kinase 83 7e-16
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 83 7e-16
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 83 7e-16
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 83 7e-16
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 82 9e-16
CE27177 [T] KOG4279 Serine/threonine protein kinase 82 9e-16
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 1e-15
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 82 1e-15
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 82 1e-15
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 82 1e-15
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 82 1e-15
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 82 2e-15
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 82 2e-15
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 82 2e-15
7302464 [R] KOG0586 Serine/threonine protein kinase 82 2e-15
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 81 2e-15
YLR096w [T] KOG0583 Serine/threonine protein kinase 81 2e-15
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 81 2e-15
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 81 2e-15
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 81 3e-15
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 81 3e-15
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 81 3e-15
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 80 4e-15
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 80 4e-15
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 80 4e-15
CE18454 [T] KOG4717 Serine/threonine protein kinase 80 4e-15
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 80 4e-15
7294217 [D] KOG0588 Serine/threonine protein kinase 80 4e-15
CE28674 [T] KOG0201 Serine/threonine protein kinase 80 5e-15
CE27768 [R] KOG0586 Serine/threonine protein kinase 80 5e-15
CE23838 [R] KOG0586 Serine/threonine protein kinase 80 5e-15
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 5e-15
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 5e-15
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 80 5e-15
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 6e-15
YCL024w [T] KOG0583 Serine/threonine protein kinase 80 6e-15
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 80 6e-15
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 80 6e-15
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 80 6e-15
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 80 6e-15
7293601 [T] KOG0577 Serine/threonine protein kinase 80 6e-15
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 79 8e-15
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 79 8e-15
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 79 8e-15
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 8e-15
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 79 1e-14
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 79 1e-14
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 79 1e-14
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 79 1e-14
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 79 1e-14
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 79 1e-14
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 79 1e-14
At2g30360 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
7300413 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
7299438 [R] KOG0586 Serine/threonine protein kinase 79 1e-14
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 79 1e-14
CE28218 [D] KOG0588 Serine/threonine protein kinase 79 1e-14
At5g01810 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 79 1e-14
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 78 2e-14
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 78 2e-14
CE15235 [R] KOG0589 Serine/threonine protein kinase 78 2e-14
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 78 2e-14
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 78 2e-14
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 78 2e-14
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 78 2e-14
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 78 2e-14
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 78 2e-14
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 78 2e-14
At5g41990 [R] KOG0584 Serine/threonine protein kinase 78 2e-14
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 78 2e-14
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 78 2e-14
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 77 3e-14
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 77 3e-14
Hs4504803 [T] KOG0197 Tyrosine kinases 77 3e-14
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 77 3e-14
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 77 3e-14
CE19898 [T] KOG0614 cGMP-dependent protein kinase 77 3e-14
CE19897 [T] KOG0614 cGMP-dependent protein kinase 77 3e-14
CE07510 [T] KOG0201 Serine/threonine protein kinase 77 3e-14
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 77 3e-14
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 77 4e-14
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 77 4e-14
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 77 4e-14
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 77 4e-14
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 77 4e-14
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 77 4e-14
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 77 4e-14
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 4e-14
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 77 4e-14
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 77 5e-14
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 77 5e-14
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 77 5e-14
Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 5e-14
Hs21735566 [T] KOG0192 Tyrosine kinase specific for activated (G... 77 5e-14
Hs21735564 [T] KOG0192 Tyrosine kinase specific for activated (G... 77 5e-14
Hs21735562 [T] KOG0192 Tyrosine kinase specific for activated (G... 77 5e-14
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 77 5e-14
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 5e-14
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 5e-14
7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 77 5e-14
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 76 7e-14
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 76 7e-14
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 76 7e-14
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 76 7e-14
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 76 7e-14
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 76 7e-14
CE05098 [T] KOG0194 Protein tyrosine kinase 76 7e-14
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 76 7e-14
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 76 7e-14
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 76 9e-14
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 76 9e-14
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 76 9e-14
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 76 9e-14
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 76 9e-14
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 76 9e-14
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 75 1e-13
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 1e-13
CE18366 [T] KOG0583 Serine/threonine protein kinase 75 1e-13
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 75 1e-13
7299793 [T] KOG0583 Serine/threonine protein kinase 75 1e-13
7295638 [T] KOG0603 Ribosomal protein S6 kinase 75 1e-13
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 75 1e-13
YPL150w [T] KOG0583 Serine/threonine protein kinase 75 2e-13
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 75 2e-13
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 75 2e-13
Hs18490991 [T] KOG0192 Tyrosine kinase specific for activated (G... 75 2e-13
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 75 2e-13
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 75 2e-13
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 75 2e-13
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 75 2e-13
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 587 bits (1513), Expect = e-168
Identities = 271/360 (75%), Positives = 319/360 (88%)
Query: 3 MQRLDEYVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV 62
+QR E++A DV SNKSN R MLVKEY++IG+GAFGTVVQAYLT D + WLGPFAIKKV
Sbjct: 11 LQRGSEFIADDVTSNKSNNTRRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKV 70
Query: 63 PAQTEYKSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYK 122
PA TEYKSREL+ILRIADHPN+VKL+YF+TH+SP D+K+YQHLAMECLPE LQ EI RY
Sbjct: 71 PAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYV 130
Query: 123 KNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL 182
N LE+PLKH++LY YQIARGMLYLH LG+CHRDIKPSNVLVDP+TG+LKICDFGSAKKL
Sbjct: 131 TNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKL 190
Query: 183 ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH 242
E NQPSISYICSR+YRAPELI+GCTQYTT+IDIWGLGCV+GEML+GKA+FQG +PLLQL
Sbjct: 191 EHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLR 250
Query: 243 EITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
EI KLLGPPDKRFIFFSNP+Y+GPLFSKPLF G+ + RFEKYFG++GPDG+DLLM +LVY
Sbjct: 251 EIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVY 310
Query: 303 EPERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFSDFELQVIGDLFPKIQP 362
EP++R SPRRILAH FF++LRN+ F P G ++P LP L+DF+DFELQ++G+ KI+P
Sbjct: 311 EPQQRLSPRRILAHQFFNELRNDDTFLPRGFTEPIKLPNLFDFNDFELQILGEFADKIKP 370
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 308 bits (789), Expect = 8e-84
Identities = 161/365 (44%), Positives = 227/365 (62%), Gaps = 16/365 (4%)
Query: 7 DEYVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQT 66
+ Y D++S K+ K +M V+E KRIG G+FGTV Q+ L+ ++ +WLGP+AIK+V
Sbjct: 21 EHYFIDDIVSIKNRQKSKMYVREGKRIGHGSFGTVTQSILSSNSIEWLGPYAIKRVVKSP 80
Query: 67 EYKSRELEILRIADHPNVVKLEYFY-THISPTD--HKLYQHLAMECLPEMLQNEILRYKK 123
+ +S ELEIL+ HPN+V LE+F+ +H + D H ++ ME +P+ L +EI Y
Sbjct: 81 KVQSLELEILQNIRHPNLVTLEFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFD 140
Query: 124 NNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLE 183
N ++P KH+KLY +QI R +L LH++ ICH D+KPSN+L+ P +GI K+CDFGSA++L+
Sbjct: 141 NGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGIAKVCDFGSAQRLD 200
Query: 184 SNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHE 243
N +Y CSR+YRAPEL++ YTT+IDIW LGC++GEM+ G+ +F+G QL E
Sbjct: 201 DNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGDSANSQLEE 260
Query: 244 ITKLLGPPDKRFIFFS---NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVL 300
I KLLG K I S S N F K F +F V+ L+ VL
Sbjct: 261 IAKLLGRFPKSSIKNSQELQDSLNDQKFKK----------FMHWFPSIEFFDVEFLLKVL 310
Query: 301 VYEPERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFSDFELQVIGDLFPKI 360
Y+ R R+++AH FFD LRNE YF P GSS P HLP L++FS E + +G+ + I
Sbjct: 311 TYDATERCDARQLMAHEFFDALRNETYFLPRGSSMPVHLPDLFNFSASEKRALGEYYNLI 370
Query: 361 QPKQD 365
P D
Sbjct: 371 VPSLD 375
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 277 bits (708), Expect = 2e-74
Identities = 145/343 (42%), Positives = 213/343 (61%), Gaps = 15/343 (4%)
Query: 23 REMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHP 82
+E+ + K IG G+FG V QA L + AIKKV +K+REL+I+R +H
Sbjct: 544 QEVSYTDTKVIGNGSFGVVFQAKLCDTGEL----VAIKKVLQDRRFKNRELQIMRKLEHC 599
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+VKL YF+ +++ +L +E +PE + +Y K +P+ ++LY YQ+ R
Sbjct: 600 NIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFR 659
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+ Y+H+LGICHRDIKP N+L+DP+T +LK+CDFGSAK+L +P++SYICSRYYRAPEL
Sbjct: 660 SLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPEL 719
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
I G YTTKID+W GCVL E+LLG+ +F G + QL E+ K+LG P + I NP+
Sbjct: 720 IFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPN 779
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGP-DGVDLLMSVLVYEPERRASPRRILAHPFFDD 321
Y F P + P ++K F P + ++L+ +L Y P R +P + AHPFFD+
Sbjct: 780 YTE--FKFPQIKSHP---WQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDE 834
Query: 322 LRNE-RYFFPSGSSQPKHLPPLYDFSDFELQVIGDLFPKIQPK 363
LR E + P+G + +PPL++F++ EL + L P++ PK
Sbjct: 835 LRMEGNHTLPNG----RDMPPLFNFTEHELSIQPSLVPQLLPK 873
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 276 bits (707), Expect = 3e-74
Identities = 147/336 (43%), Positives = 204/336 (59%), Gaps = 13/336 (3%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYF 90
K +G G+FG V+Q +L + K AIK+V +K+REL+I+RI HPN+V L +
Sbjct: 36 KVVGSGSFGVVMQVHLIESDSK----AAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAY 91
Query: 91 YTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHAL 150
Y ++Y +L +E +PE + Y + L +P+ VKLY YQ+ R + Y+HA
Sbjct: 92 YYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHAS 151
Query: 151 GICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYT 210
GICHRDIKP N+L+DP+ GILK+CDFGSAK L + +P++SYICSRYYRAPELI G T YT
Sbjct: 152 GICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYT 211
Query: 211 TKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSK 270
IDIW GCV+ E++LG +F G + QL EI K+LG P + I NP+Y F
Sbjct: 212 HAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTMNPNYMEHRF-- 269
Query: 271 PLFEGAPKARFEKYFGYAGP-DGVDLLMSVLVYEPERRASPRRILAHPFFDDLRN---ER 326
P P +R F + P D +DLL +L Y P R + + HPFFD+LR+ +
Sbjct: 270 PQIRPQPLSR---VFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELRDPNTKL 326
Query: 327 YFFPSGSSQPKHLPPLYDFSDFELQVIGDLFPKIQP 362
+ + + P+HLP L++FS FEL + DL K+ P
Sbjct: 327 HNSRNPDASPRHLPELFNFSPFELSIRPDLNQKLIP 362
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 268 bits (684), Expect = 1e-71
Identities = 138/314 (43%), Positives = 193/314 (60%), Gaps = 10/314 (3%)
Query: 24 EMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPN 83
E+ + K IG G+FG V A L+ N+ AIKKV +K+REL+I+R +HPN
Sbjct: 33 EISYYDQKVIGNGSFGVVFLAKLSTTNEM----VAIKKVLQDKRFKNRELQIMRKLNHPN 88
Query: 84 VVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
+VKL+YF+ +LY +L +E +PE + Y K ++P+ +VKLY YQ+ R
Sbjct: 89 IVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRS 148
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
+ Y+H++GICHRDIKP N+L+DP++G+LK+CDFGSAK L N+P++SYICSRYYRAPELI
Sbjct: 149 LAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELI 208
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSY 263
G T YT ID+W G V+ E+LLG+ +F G + QL EI K+LG P + I NP+Y
Sbjct: 209 FGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNY 268
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGP-DGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
F P + P + K F P + +DL+ ++ Y P R +P+ H FFD+L
Sbjct: 269 KE--FKFPQIKAHP---WNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFFDEL 323
Query: 323 RNERYFFPSGSSQP 336
RN PSG P
Sbjct: 324 RNPDARLPSGRPLP 337
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 267 bits (682), Expect = 2e-71
Identities = 143/330 (43%), Positives = 197/330 (59%), Gaps = 12/330 (3%)
Query: 23 REMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHP 82
+E+ + K IG G+FG V QA L + AIKKV +K+REL+I+R DH
Sbjct: 115 QEVAYTDIKVIGNGSFGVVYQARLAETREL----VAIKKVLQDKRFKNRELQIMRKLDHC 170
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+V+L YF+ +LY +L +E +PE + + K L +P+ +VK+Y YQ+ R
Sbjct: 171 NIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFR 230
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+ Y+H+ G+CHRDIKP N+LVDP T +LK+CDFGSAK+L +P++SYICSRYYRAPEL
Sbjct: 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPEL 290
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
I G T YT+ ID+W GCVL E+LLG+ +F G + QL EI K+LG P + I NP+
Sbjct: 291 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 350
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
Y F P + P + K P+ + L S+L Y P R SP AH FFD+L
Sbjct: 351 YTE--FKFPQIKAHPWTKVFK--SRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
Query: 323 RNERYFFPSGSSQPKHLPPLYDFSDFELQV 352
R P+ + LPPL++FS EL +
Sbjct: 407 RCLGTQLPNN----RPLPPLFNFSAGELSI 432
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 267 bits (682), Expect = 2e-71
Identities = 143/330 (43%), Positives = 197/330 (59%), Gaps = 12/330 (3%)
Query: 23 REMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHP 82
+E+ + K IG G+FG V QA L + AIKKV +K+REL+I+R DH
Sbjct: 115 QEVAYTDIKVIGNGSFGVVYQARLAETREL----VAIKKVLQDKRFKNRELQIMRKLDHC 170
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+V+L YF+ +LY +L +E +PE + + K L +P+ +VK+Y YQ+ R
Sbjct: 171 NIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFR 230
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+ Y+H+ G+CHRDIKP N+LVDP T +LK+CDFGSAK+L +P++SYICSRYYRAPEL
Sbjct: 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPEL 290
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
I G T YT+ ID+W GCVL E+LLG+ +F G + QL EI K+LG P + I NP+
Sbjct: 291 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 350
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
Y F P + P + K P+ + L S+L Y P R SP AH FFD+L
Sbjct: 351 YTE--FKFPQIKAHPWTKVFK--SRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
Query: 323 RNERYFFPSGSSQPKHLPPLYDFSDFELQV 352
R P+ + LPPL++FS EL +
Sbjct: 407 RCLGTQLPNN----RPLPPLFNFSAGELSI 432
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 265 bits (678), Expect = 6e-71
Identities = 148/338 (43%), Positives = 202/338 (58%), Gaps = 19/338 (5%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA + AIKKV YK+REL+ +R+ DHPNVV L++ +
Sbjct: 79 VGHGSFGVVFQAKCLETGET----VAIKKVLQDRRYKNRELQTMRLLDHPNVVSLKHCFF 134
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-ALG 151
+ D +LY +L +E +PE + I Y K N +PL +VKLY YQI R + Y+H +G
Sbjct: 135 STTEKD-ELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYIHRCIG 193
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRDIKP N+LV+P T +K+CDFGSAK L +P+ISYICSRYYRAPELI G T+YTT
Sbjct: 194 VCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTT 253
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
ID+W GCVL E+LLG+ +F G + QL EI K+LG P + I NP+Y F P
Sbjct: 254 AIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTE--FKFP 311
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ VDL+ +L Y P R + L HPFFD+LR+ P+
Sbjct: 312 QIKAHPWHKI--FHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELRDPNARLPN 369
Query: 332 GSSQPKHLPPLYDFSDFEL-----QVIGDLFPKIQPKQ 364
G + LPPL++F EL +++ L P+ KQ
Sbjct: 370 G----RFLPPLFNFKPHELKGVPVEMVAKLVPEHARKQ 403
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 263 bits (673), Expect = 2e-70
Identities = 148/320 (46%), Positives = 196/320 (61%), Gaps = 16/320 (5%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
IG G+FG V QA +K AIKKV YK+REL+I+R+ DHPNVV+L++ +
Sbjct: 108 IGTGSFGVVFQAKCLETEEK----VAIKKVLQDKRYKNRELQIMRMLDHPNVVELKHSFF 163
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-ALG 151
+ D +LY +L +E +PE + Y K N +PL +++LY YQI R M YLH +G
Sbjct: 164 STTEKD-ELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQICRAMNYLHQVVG 222
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRDIKP N+LV+ T +KICDFGSAK L +P+ISYICSRYYRAPELI G T+YT+
Sbjct: 223 VCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIPGEPNISYICSRYYRAPELIFGATEYTS 282
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
ID+W +GCV+ E+ LG +F G + QL EI K+LG P + I NP YN F P
Sbjct: 283 AIDMWSVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNMNPRYND--FKFP 340
Query: 272 LFEGAPKARFEKYF-GYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFP 330
+ P + K F P+ +DL +L Y P R + AHPFFDDLR+ R P
Sbjct: 341 QIKAQP---WHKIFRRQVSPEAMDLASRLLQYSPNLRCTALEACAHPFFDDLRDPRASLP 397
Query: 331 SGSSQPKHLPPLYDFSDFEL 350
+G + LPPL+DF+ EL
Sbjct: 398 NG----RALPPLFDFTAQEL 413
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 263 bits (672), Expect = 3e-70
Identities = 145/319 (45%), Positives = 195/319 (60%), Gaps = 14/319 (4%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA ++ AIKKV YK+REL+I+R+ DHPNVV+L + +
Sbjct: 144 VGTGSFGVVFQAKCLETGEQ----VAIKKVLQDKRYKNRELQIMRLQDHPNVVRLRHSFF 199
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-ALG 151
+ D +LY +L +E +PE + Y K N +P+ V+LY YQI R + YLH +G
Sbjct: 200 STTDKD-ELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQICRALNYLHRVVG 258
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRDIKP N+LV+PQT LKICDFGSAK L +P+ISYICSRYYRAPELI G T+YT
Sbjct: 259 VCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVPGEPNISYICSRYYRAPELIFGATEYTN 318
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
ID+W GCV+ E+LLG+ +F G + QL EI K+LG P + I NP+Y F P
Sbjct: 319 AIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREEIRCMNPNYTE--FKFP 376
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ VDL+ +L Y P R + AHPFFDDLR+ P+
Sbjct: 377 QIKAHPWHKI--FHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFFDDLRDPNVSLPN 434
Query: 332 GSSQPKHLPPLYDFSDFEL 350
G + LPPL++F+ EL
Sbjct: 435 G----RALPPLFNFTAQEL 449
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 261 bits (668), Expect = 9e-70
Identities = 142/314 (45%), Positives = 193/314 (61%), Gaps = 14/314 (4%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA + AIKKV YK+REL+ +R+ DHPNVV L++ +
Sbjct: 75 VGHGSFGVVFQAKCLETGET----VAIKKVLQDRRYKNRELQTMRLLDHPNVVSLKHCFF 130
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-ALG 151
+ D +LY +L +E +PE + I Y K N +PL +VKLY YQI R + Y+H +G
Sbjct: 131 STTEKD-ELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSYIHRCIG 189
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRDIKP N+LV+P T +K+CDFGSAK L +P+ISYICSRYYRAPELI G T+YTT
Sbjct: 190 VCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTT 249
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
ID+W GCVL E+LLG+ +F G + QL EI K+LG P + I NP+Y F P
Sbjct: 250 AIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTE--FKFP 307
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ VDL+ +L Y P R++ L HPFFD+LR+ P+
Sbjct: 308 QIKAHPWHKI--FHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELRDPNARLPN 365
Query: 332 GSSQPKHLPPLYDF 345
G + LPPL++F
Sbjct: 366 G----RFLPPLFNF 375
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 261 bits (666), Expect = 1e-69
Identities = 143/363 (39%), Positives = 217/363 (59%), Gaps = 18/363 (4%)
Query: 7 DEYVAHDVISNKSNVKREMLVKEYKRI-GQGAFGTVVQAYL--TPDNQKWLGPFAIKKVP 63
D ++ V+++ + +++ + E R+ G G+FG V+QA L TP G A+K+V
Sbjct: 4 DSHLETKVVTDGTTGEKKTISYEPCRVLGSGSFGVVIQAKLVGTP------GFIAVKRVL 57
Query: 64 AQTEYKSRELEILRIADHPNVVKL-EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYK 122
YK+REL+I+R HPN++KL +F+TH +P+ + + L +E +PE + +++ Y
Sbjct: 58 QDKRYKNRELQIMRAISHPNIIKLIAFFHTH-NPSKDETHLCLLLEYMPETVFDDMRWYT 116
Query: 123 KNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL 182
+ +P +KLYA+Q+ R + YLH+ G+CHRDIKP N+LVD +TGILK+CDFGSAK L
Sbjct: 117 RRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVL 176
Query: 183 ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH 242
++P++SYICSRYYRAPEL+ G T YTTKID+W CV+ E+ +G+ +F G + QL
Sbjct: 177 VPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLV 236
Query: 243 EITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
EI ++LG P I NP+Y + L P + +DLL +L Y
Sbjct: 237 EIIRVLGTPSYHEISVMNPNY----VNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTY 292
Query: 303 EPERRASPRRILAHPFFDDLRNERYFFPSGSSQ---PKHLPPLYDFSDFELQVIGDLFPK 359
P +R S +L HPFFD+LR+ + + +HLPPL++F+ EL + +L
Sbjct: 293 VPSKRISAIEVLTHPFFDELRDPNCMYHCSRDEGTIERHLPPLFNFNLAELSIRPNLNKA 352
Query: 360 IQP 362
I P
Sbjct: 353 ILP 355
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 258 bits (660), Expect = 7e-69
Identities = 146/338 (43%), Positives = 202/338 (59%), Gaps = 21/338 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+GQG+FG V QA + AIKKV YK+REL+ +R+ DHPNVV L++ +
Sbjct: 80 VGQGSFGIVFQAKCLETGET----VAIKKVLQDKRYKNRELQTMRLLDHPNVVSLKHCFF 135
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHA-LG 151
+ D +LY +L +E +PE + Y + N +P+ +VKLY YQI R + Y+H +G
Sbjct: 136 STTEKD-ELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIHGGVG 194
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRDIKP N+LV+P T +K+CDFGSAK L +P+ISYICSRYYRAPELI G T+YTT
Sbjct: 195 VCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTT 254
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
IDIW GCVL E+LLG+ +F G + QL EI K+LG P + I NP+Y F P
Sbjct: 255 TIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTE--FKFP 312
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ VDL+ +L Y P R++ + HPFFD+LR+ P+
Sbjct: 313 QIKAHPWHKI--FHKRTPPEAVDLVSRLLQYSPNLRST--AAIVHPFFDELRDPNTRLPN 368
Query: 332 GSSQPKHLPPLYDFSDFE-----LQVIGDLFPKIQPKQ 364
G + LPPL++F E L+++ L P KQ
Sbjct: 369 G----RALPPLFNFKPQELKGASLELLSKLIPDHARKQ 402
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 257 bits (657), Expect = 2e-68
Identities = 137/328 (41%), Positives = 194/328 (58%), Gaps = 12/328 (3%)
Query: 23 REMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHP 82
+E+ + K IG G+FG V QA L + AIKKV +K+REL+I+R DH
Sbjct: 52 QEVSYTDTKVIGNGSFGVVYQAKLCDSGEL----VAIKKVLQDKRFKNRELQIMRKLDHC 107
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+V+L YF+ ++Y +L ++ +PE + Y + LP+ +VKLY YQ+ R
Sbjct: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+ Y+H+ GICHRDIKP N+L+DP T +LK+CDFGSAK+L +P++SYICSRYYRAPEL
Sbjct: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPEL 227
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
I G T YT+ ID+W GCVL E+LLG+ +F G + QL EI K+LG P + I NP+
Sbjct: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 287
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
Y F P + P + + P+ + L +L Y P R +P AH FFD+L
Sbjct: 288 YTE--FKFPQIKAHPWTKV--FRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDEL 343
Query: 323 RNERYFFPSGSSQPKHLPPLYDFSDFEL 350
R+ P+G + P L++F+ EL
Sbjct: 344 RDPNVKHPNG----RDTPALFNFTTQEL 367
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 257 bits (656), Expect = 2e-68
Identities = 141/332 (42%), Positives = 197/332 (58%), Gaps = 18/332 (5%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA + AIKKV YK+REL+++R DHPNV+ L++ +
Sbjct: 76 VGTGSFGIVFQAKCLETGES----VAIKKVLQDRRYKNRELQLMRPMDHPNVISLKHCFF 131
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHAL-G 151
+ D +L+ +L ME +PE L + Y +N +P+ +VKLY YQI RG+ Y+H + G
Sbjct: 132 STTSRD-ELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTVPG 190
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRD+KP N+LVDP T +K+CDFGSAK L +P+ISYICSRYYRAPELI G T+YT
Sbjct: 191 VCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTA 250
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
IDIW GCVL E+LLG+ +F G + QL EI K+LG P + I NP+Y F P
Sbjct: 251 SIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTD--FRFP 308
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ +DL +L Y P R + AHPFF++LR P+
Sbjct: 309 QIKAHPWHKV--FHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPNARLPN 366
Query: 332 GSSQPKHLPPLYDFSD----FELQVIGDLFPK 359
G + LPPL++F +++I L P+
Sbjct: 367 G----RPLPPLFNFKQELGGASMELINRLIPE 394
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 256 bits (655), Expect = 3e-68
Identities = 151/341 (44%), Positives = 202/341 (58%), Gaps = 23/341 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEY-FY 91
+G G+FG V QA + AIKKV YK+REL+I+++ DHPNVV L++ FY
Sbjct: 88 VGTGSFGMVFQAKCRETGEV----VAIKKVLQDKRYKNRELQIMQMLDHPNVVCLKHSFY 143
Query: 92 THISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-AL 150
+ + ++Y +L +E +PE + Y + N +PL +VKLY YQI RG+ YLH
Sbjct: 144 SRTE--NEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYLHNCC 201
Query: 151 GICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYT 210
G+CHRDIKP N+LV+P T LKICDFGSAK L +P+ISYICSRYYRAPELI G T+YT
Sbjct: 202 GLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYT 261
Query: 211 TKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSK 270
T IDIW GCV+ E+LLG+ +F G + QL EI K+LG P + I NP+Y F
Sbjct: 262 TAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTE--FKF 319
Query: 271 PLFEGAPKAR-FEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFF 329
P + P + F+K P+ VDLL Y P R + HPFFD+LR+
Sbjct: 320 PQIKPHPWHKVFQKRL---PPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELRDPNARL 376
Query: 330 PSGSSQPKHLPPLYDFSDFEL-----QVIGDLFPKIQPKQD 365
P+G + LPPL++F EL + + L P+ KQ+
Sbjct: 377 PNG----RPLPPLFNFKPQELSGIPPETVDRLVPEHARKQN 413
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 256 bits (654), Expect = 4e-68
Identities = 138/339 (40%), Positives = 195/339 (56%), Gaps = 21/339 (6%)
Query: 23 REMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHP 82
+E+ + K IG G+FG V QA L + AIKKV +K+REL+I+R DH
Sbjct: 52 QEVSYTDTKVIGNGSFGVVYQAKLCDSGEL----VAIKKVLQDKRFKNRELQIMRKLDHC 107
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+V+L YF+ ++Y +L ++ +PE + Y + LP+ +VKLY YQ+ R
Sbjct: 108 NIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFR 167
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+ Y+H+ GICHRDIKP N+L+DP T +LK+CDFGSAK+L +P++SYICSRYYRAPEL
Sbjct: 168 SLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPEL 227
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
I G T YT+ ID+W GCVL E+LLG+ +F G + QL EI K+LG P + I NP+
Sbjct: 228 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPN 287
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGY-----------AGPDGVDLLMSVLVYEPERRASPR 311
Y F P + P + G+ P+ + L +L Y P R +P
Sbjct: 288 YTE--FKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPL 345
Query: 312 RILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFSDFEL 350
AH FFD+LR+ P+G + P L++F+ EL
Sbjct: 346 EACAHSFFDELRDPNVKLPNG----RDTPALFNFTTQEL 380
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 255 bits (651), Expect = 8e-68
Identities = 139/314 (44%), Positives = 190/314 (60%), Gaps = 14/314 (4%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA + AIKKV YK+REL+++R+ DHPNVV L++ +
Sbjct: 78 VGTGSFGIVFQAKCLETGES----VAIKKVLQDRRYKNRELQLMRLMDHPNVVSLKHCFF 133
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-ALG 151
+ D +L+ +L ME +PE L + Y +N +P+ +VKLY YQI RG+ Y+H A G
Sbjct: 134 STTTRD-ELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTAPG 192
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRD+KP N+LVDP T K+CDFGSAK L + +ISYICSRYYRAPELI G T+YT+
Sbjct: 193 VCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTS 252
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
IDIW GCVL E+LLG+ +F G + QL EI K+LG P + I NP+Y F P
Sbjct: 253 SIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTD--FRFP 310
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ +DL +L Y P R + AHPFF++LR P+
Sbjct: 311 QIKAHPWHKV--FHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPNARLPN 368
Query: 332 GSSQPKHLPPLYDF 345
G + LPPL++F
Sbjct: 369 G----RPLPPLFNF 378
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 254 bits (648), Expect = 2e-67
Identities = 139/314 (44%), Positives = 188/314 (59%), Gaps = 14/314 (4%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA + AIKKV YK+REL+++R+ DHPNVV L++ +
Sbjct: 46 VGTGSFGIVFQAKCLETGET----VAIKKVLQDRRYKNRELQLMRVMDHPNVVCLKHCFF 101
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHAL-G 151
+ D +L+ +L ME +PE L + Y N +PL +VKLY YQI RG+ Y+H + G
Sbjct: 102 STTSKD-ELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAG 160
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
+CHRD+KP N+LVDP T +KICDFGSAK+L + +ISYICSR+YRAPELI G T+YTT
Sbjct: 161 VCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANISYICSRFYRAPELIFGATEYTT 220
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSKP 271
IDIW GCVL E+LLG+ +F G + QL EI K+LG P + I NP Y F P
Sbjct: 221 SIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPHYTD--FRFP 278
Query: 272 LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
+ P + + P+ +D +L Y P R + AHPFFD+LR P+
Sbjct: 279 QIKAHPWHKI--FHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDELREPNARLPN 336
Query: 332 GSSQPKHLPPLYDF 345
G + PPL++F
Sbjct: 337 G----RPFPPLFNF 346
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 252 bits (643), Expect = 7e-67
Identities = 146/341 (42%), Positives = 202/341 (58%), Gaps = 23/341 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG V QA + AIKKV YK+REL+I+++ DHPN V L++ +
Sbjct: 89 VGTGSFGMVFQAKCRETGEV----VAIKKVLQDKRYKNRELQIMQMLDHPNAVALKHSF- 143
Query: 93 HISPTDHK-LYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH-AL 150
S TD++ +Y +L +E +PE + Y + N +PL +VKLY YQI R + Y+H +
Sbjct: 144 -FSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALAYIHNSF 202
Query: 151 GICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYT 210
G+CHRDIKP N+LV+P T LKICDFGSAK L +P++SYICSRYYRAPELI G ++YT
Sbjct: 203 GLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNVSYICSRYYRAPELIFGASEYT 262
Query: 211 TKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSK 270
T IDIW GCV+ E+LLG+ +F G + QL EI K+LG P + I NP+Y F
Sbjct: 263 TAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTE--FKF 320
Query: 271 PLFEGAPKAR-FEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFF 329
P + P + F+K P+ VDLL Y P R + HP FD+LR+
Sbjct: 321 PQIKPHPWHKVFQKRL---PPEAVDLLCRFFQYSPNLRCTALEACIHPLFDELRDPNTRL 377
Query: 330 PSGSSQPKHLPPLYDFSDFEL-----QVIGDLFPKIQPKQD 365
P+G + LPPL++F EL +++ L P+ KQ+
Sbjct: 378 PNG----RPLPPLFNFKPQELSGIPPEIVNRLVPEHARKQN 414
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 238 bits (608), Expect = 8e-63
Identities = 123/297 (41%), Positives = 182/297 (60%), Gaps = 9/297 (3%)
Query: 70 SRELEILRIADHPNVVKL-EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLEL 128
+REL+I+R HPN++KL +F+TH +P+ + + L +E +PE + +++ Y + +
Sbjct: 33 NRELQIMRAISHPNIIKLIAFFHTH-NPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSI 91
Query: 129 PLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS 188
P +KLYA+Q+ R + YLH+ G+CHRDIKP N+LVD +TGILK+CDFGSAK L ++P+
Sbjct: 92 PNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPN 151
Query: 189 ISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLL 248
+SYICSRYYRAPEL+ G T YTTKID+W CV+ E+ +G+ +F G + QL EI ++L
Sbjct: 152 VSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVL 211
Query: 249 GPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRA 308
G P I NP+Y + L P + +DLL +L Y P +R
Sbjct: 212 GTPSYHEISVMNPNY----VNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRI 267
Query: 309 SPRRILAHPFFDDLRNERYFFPSGSSQ---PKHLPPLYDFSDFELQVIGDLFPKIQP 362
S +L HPFFD+LR+ + + +HLPPL++F+ EL + +L I P
Sbjct: 268 SAIEVLTHPFFDELRDPNCMYHCSRDEGTIERHLPPLFNFNLAELSIRPNLNKAILP 324
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 229 bits (583), Expect = 6e-60
Identities = 122/294 (41%), Positives = 174/294 (58%), Gaps = 15/294 (5%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
+G G+FG VV + NQK AIKKV YK+RELE +++ HPN V L+Y++
Sbjct: 170 VGHGSFGVVVTTVIIETNQK----VAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFY 225
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHALG- 151
D ++Y +L ++ +P+ L + + +++P +K YAYQ+ + + YLH +
Sbjct: 226 EKDEED-EVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPR 284
Query: 152 ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTT 211
ICHRDIKP N+LVDP T KICDFGSAK L+ +QP++SYICSRYYRAPEL+ G T Y+
Sbjct: 285 ICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSN 344
Query: 212 KIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFS-- 269
++D+W CV+ E+LLGK +F G + QL EI K++G P K I NP+Y +F
Sbjct: 345 QVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNI 404
Query: 270 KPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLR 323
KP+ + F PD +DLL L Y P R P + L +FD+ +
Sbjct: 405 KPI-------TLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDETK 451
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 226 bits (577), Expect = 3e-59
Identities = 124/316 (39%), Positives = 182/316 (57%), Gaps = 11/316 (3%)
Query: 9 YVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEY 68
Y AH + N ++ + +G G+FG V + N+K AIKKV +
Sbjct: 21 YYAHPPPTIDPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEK----VAIKKVLQDKRF 76
Query: 69 KSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLEL 128
K+RELEI+++ H N++ L+YF+ D ++Y +L +E +P+ L + + +
Sbjct: 77 KNRELEIMKMLSHINIIDLKYFFYERDSQD-EIYLNLILEYMPQSLYQRLRHFVHQRTPM 135
Query: 129 PLKHVKLYAYQIARGMLYLHALG-ICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQP 187
+K Y +Q+ + + YLH +CHRDIKP N+LVDP+T LK+CDFGSAK+L+ +P
Sbjct: 136 SRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEP 195
Query: 188 SISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKL 247
++SYICSRYYRAPELI G T YT +IDIW GCV+ E+LLG+ +F G + QL EI K+
Sbjct: 196 NVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKI 255
Query: 248 LGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERR 307
LG P K+ I NP+Y F P + P +R F V+ L VL Y+P R
Sbjct: 256 LGTPSKQEICSMNPNYMEHKF--PQIKPIPLSR---VFKKEDDQTVEFLADVLKYDPLER 310
Query: 308 ASPRRILAHPFFDDLR 323
+ + L P+FD+L+
Sbjct: 311 FNALQCLCSPYFDELK 326
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 223 bits (567), Expect = 4e-58
Identities = 133/358 (37%), Positives = 199/358 (55%), Gaps = 27/358 (7%)
Query: 12 HDVISNK---SNVKREMLVK--EYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQT 66
H V++ + S + RE+ ++ + IG G+FG V +A L +++ P AIKK+
Sbjct: 17 HTVMAKRGTGSKLDREVEIQFTNLQLIGTGSFGAVYKAVLRENDE----PIAIKKIKVDD 72
Query: 67 EYKSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNL 126
+KSREL I+ DHPN+++L Y+Y + + ME +P+ L ++ N+
Sbjct: 73 RFKSRELTIMHEMDHPNIIRLLYYYV----MQQENCLNFVMEFMPKDLAYVHRQFAHNDK 128
Query: 127 ELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQ 186
++P +KLY +Q+ RG+ +LH I HRDIKP N+LVD GILKICDFGSAK+LE N+
Sbjct: 129 QMPAYSIKLYMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEKNE 188
Query: 187 PSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITK 246
P+I+YICSRYYRAPELI G Y T ID W +G V+GE+L +F + L K
Sbjct: 189 PNITYICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIK 248
Query: 247 LLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFG-YAGPDGVDLLMSVLVYEPE 305
G P K + N Y ++ +K+ G ++LL S++ +P+
Sbjct: 249 AFGTPSKEDMAKWNYEY-----VHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPK 303
Query: 306 RRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFSDFEL----QVIGDLFPK 359
R P L P+FDDLR+ Y PSG+ +PPL+D+ + E ++I D+FP+
Sbjct: 304 LRIKPYEALTLPYFDDLRDPHYKLPSGAP----IPPLFDWLEREYIANHEIIKDIFPR 357
>7298004 [G] KOG0658 Glycogen synthase kinase-3
Length = 392
Score = 163 bits (413), Expect = 3e-40
Identities = 120/343 (34%), Positives = 171/343 (48%), Gaps = 32/343 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEIL-RIADHPNVVKLEYFY 91
IG G+FG V QA++ + A+K+ + E EI+ ++ DH N+V+L
Sbjct: 50 IGSGSFGRVYQAHVNESEEI----VAVKQTLYNPKLSQGEAEIMGQLKDHNNIVRLIMHS 105
Query: 92 THISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELP--LKHVKLYAYQIARGMLYLHA 149
+ Y L ME +P L + I Y L+ L +V++ +YQ+ RG+ YLH
Sbjct: 106 SVSLGFPSVDYVLLVMEYMPMTLLDYI-NYHLTVLQPAERLINVRILSYQMFRGLGYLHL 164
Query: 150 LGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQY 209
LGI HRD+KP N+L+D Q +LK+ DFGSAK L +PSISYICSR YRAPEL G Y
Sbjct: 165 LGISHRDVKPENLLIDNQKMVLKLSDFGSAKLLVPQEPSISYICSRLYRAPELFAGYELY 224
Query: 210 TTKIDIWGLGCVLGEMLLGKAVFQGHQ-PLLQLHEITKLLGPP--DKRFIFFS------N 260
+ +DIW GCVL E+L G +F H+ QL I +LG ++ S +
Sbjct: 225 SCAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGTDGLERAPEILSKCGNSLH 284
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
P P ++ L P+ D LL S +YE R SP +H +D
Sbjct: 285 PRTTRPSWNYLLNTAVPQ------------DLCGLLNSCFIYEAAARISPMMACSHGSYD 332
Query: 321 DLR-NERYFFPSGSSQPKHLPPLYDFSDFELQVIGDLFPKIQP 362
+LR + P + P LPPL+DF+ E+ L+ + P
Sbjct: 333 ELRIMDAMALPMPNGNP--LPPLFDFNSLEMGTDPKLWVNLLP 373
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 162 bits (411), Expect = 6e-40
Identities = 106/325 (32%), Positives = 169/325 (51%), Gaps = 27/325 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
K IG+GA+G V + N++ AIKK+ E + REL++LR H NV
Sbjct: 36 KPIGRGAYGVVCSSINRETNER----VAIKKIHNVFENRVDALRTLRELKLLRHVRHENV 91
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L+ + P + ++ + + + E++ ++ + K++ L H K + +Q+ RG+
Sbjct: 92 IALKDV---MLPANRSSFKDVYL--VYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLRGL 146
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS-YICSRYYRAPELI 203
YLH+ I HRD+KP N+LV+ LKICDFG A+ + N+ ++ Y+ +R+YRAPEL+
Sbjct: 147 KYLHSANILHRDLKPGNLLVNANCD-LKICDFGLARTSQGNEQFMTEYVVTRWYRAPELL 205
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPS 262
+ C Y T ID+W +GC+ E+L K +F G + L QL I ++G + I F NP
Sbjct: 206 LCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQESDIRFIDNPK 265
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
+ S P G + A P +DLL +LV++P +R S L HP+ L
Sbjct: 266 ARRFIKSLPYSRG---THLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLHPYMAGL 322
Query: 323 RNERYFFPSGSSQPKHLPPLYDFSD 347
F GS+ P H+P D +
Sbjct: 323 ------FDPGSNPPAHVPISLDIDE 341
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 160 bits (406), Expect = 2e-39
Identities = 103/316 (32%), Positives = 166/316 (51%), Gaps = 19/316 (6%)
Query: 9 YVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP----- 63
YV ++V V R+ V + IG+GA G V A + +K AIKK+
Sbjct: 58 YVQYNVYGQLFEVSRKY-VPPIRPIGRGACGIVCAAVNSVTGEK----VAIKKIGNAFDN 112
Query: 64 -AQTEYKSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYK 122
+ RE+++LR DH NV+ ++ + P ++ + + + E++ ++ R
Sbjct: 113 IIDAKRTLREIKLLRHMDHENVITIKDI---VRPPQRDIFNDVYI--VYELMDTDLQRIL 167
Query: 123 KNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL 182
++N L + YQ+ RG+ Y+H+ I HRD++PSNVL++ + LKI DFG A+
Sbjct: 168 RSNQTLTSDQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNE-LKIGDFGLARTT 226
Query: 183 ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH 242
Y+ +R+YRAPEL++ C++YT IDIW +GC+LGE++ G+ +F G + QL
Sbjct: 227 SDTDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLR 286
Query: 243 EITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
IT+L+G PD + F S N + + L PK +F F +DLL +LV+
Sbjct: 287 LITELVGSPDNSSLGFLR-SDNARRYVRQL-PRYPKQQFAARFPKMPTTAIDLLERMLVF 344
Query: 303 EPERRASPRRILAHPF 318
+P RR S L H +
Sbjct: 345 DPNRRISVDEALGHAY 360
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 160 bits (404), Expect = 4e-39
Identities = 101/322 (31%), Positives = 170/322 (52%), Gaps = 19/322 (5%)
Query: 9 YVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP----- 63
YV ++V N V R+ V + IG+GA+G V A + ++ AIKK+
Sbjct: 26 YVQYNVYGNLFEVSRKY-VPPLRPIGRGAYGIVCAATNSETGEE----VAIKKIGNAFDN 80
Query: 64 -AQTEYKSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYK 122
+ RE+++L+ DH NV+ ++ I P + + + + + E++ ++ +
Sbjct: 81 IIDAKRTLREIKLLKHMDHENVIAVKDI---IKPPQRENFNDVYI--VYELMDTDLHQII 135
Query: 123 KNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL 182
++N L H + + YQ+ RG+ Y+H+ + HRD+KPSN+L++ LK+ DFG A+
Sbjct: 136 RSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCD-LKLGDFGLARTK 194
Query: 183 ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH 242
Y+ +R+YRAPEL++ C++YT IDIW +GC+LGE + + +F G + QL
Sbjct: 195 SETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLR 254
Query: 243 EITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
IT+L+G PD + F S N + + L + P+ F F VDLL +LV+
Sbjct: 255 LITELIGSPDDSSLGFLR-SDNARRYVRQLPQ-YPRQNFAARFPNMSAGAVDLLEKMLVF 312
Query: 303 EPERRASPRRILAHPFFDDLRN 324
+P RR + L HP+ L +
Sbjct: 313 DPSRRITVDEALCHPYLAPLHD 334
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 158 bits (399), Expect = 1e-38
Identities = 102/305 (33%), Positives = 164/305 (53%), Gaps = 30/305 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILRIAD 80
++ ++IG+G +G V +A K G A+KK+ TE + RE+ +L+ +
Sbjct: 5 QKVEKIGEGTYGVVYKA-----RNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
HPN+VKL + T++KLY L E L + L+ + + LPL +K Y +Q+
Sbjct: 60 HPNIVKL----LDVIHTENKLY--LVFEFLHQDLKKFMDASALTGIPLPL--IKSYLFQL 111
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRA 199
+G+ + H+ + HRD+KP N+L++ + G +K+ DFG A+ + ++ + + +YRA
Sbjct: 112 LQGLAFCHSHRVLHRDLKPQNLLINTE-GAIKLADFGLARAFGVPVRTYTHEVVTLWYRA 170
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--F 257
PE+++GC Y+T +DIW LGC+ EM+ +A+F G + QL I + LG PD+
Sbjct: 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGV 230
Query: 258 FSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
S P Y KP F + F K DG LL +L Y+P +R S + LAHP
Sbjct: 231 TSMPDY------KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
Query: 318 FFDDL 322
FF D+
Sbjct: 285 FFQDV 289
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 157 bits (397), Expect = 2e-38
Identities = 97/306 (31%), Positives = 163/306 (52%), Gaps = 19/306 (6%)
Query: 14 VISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSREL 73
++ ++ +E+ + + IG+G+FG VV+ + D + FA+K+V Y +REL
Sbjct: 43 LVRSRCGEVKEVRYRYVEMIGRGSFGVVVK--IMDDRHNF---FALKRVYQDRRYHNREL 97
Query: 74 EILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHV 133
IL DHPN+V+L ++ H T Y ++ + + L+ Y K N + + +
Sbjct: 98 GILMEVDHPNIVRLVSYF-HTDKTSSGAYLNIITDFVGMNLEE----YIKANRGVETEEI 152
Query: 134 KLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYIC 193
+ QI G+ YLH ICHRD+KPSN+L+D G++KICD GSAK ++S + +I+YIC
Sbjct: 153 RSVYRQILEGLRYLHEKNICHRDMKPSNILIDTN-GLVKICDLGSAKVIKSGERNITYIC 211
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDK 253
SR+YRAPE ++ +Y KIDIW +GCV+ E +F+G L+ I +++
Sbjct: 212 SRFYRAPENLLDYKEYDFKIDIWSVGCVIAEFRHPGPIFKGDTSGSTLNRILEIVRVTSD 271
Query: 254 RFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRI 313
I L +G ++ + F ++ PD +++L L + P +R++ +
Sbjct: 272 DLIGLG-------CLKPDLKQGVGIRKYLEAF-FSDPDLLEVLEKSLAFSPCKRSTASEL 323
Query: 314 LAHPFF 319
L FF
Sbjct: 324 LRKQFF 329
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 156 bits (394), Expect = 5e-38
Identities = 95/302 (31%), Positives = 162/302 (53%), Gaps = 22/302 (7%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA------QTEYKSRELEILRIADHPNVVK 86
IG+GA G V A + N+K AIKK+ + + RE+++LR DH N+V
Sbjct: 66 IGRGACGIVCSAVDSETNEK----VAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVA 121
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+ I P ++ + + + E+++ ++ R K++ EL H + YQI RG+ Y
Sbjct: 122 IRDV---ILPPQRDSFEDVYI--VNELMEFDLYRTLKSDQELTKDHGMYFMYQILRGLKY 176
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ + HRD+KPSN+L+ Q LKICDFG A+ + Y+ +R+YRAPEL++G
Sbjct: 177 IHSANVLHRDLKPSNLLLSTQCD-LKICDFGLARATPESNLMTEYVVTRWYRAPELLLGS 235
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGP 266
+ YT ID+W +GC+ E++ + +F G + QL + +L+G P + + +
Sbjct: 236 SDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSEEELGSLSEYAKRY 295
Query: 267 LFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF---FDDLR 323
+ P P+ F + F P +DL+ +L ++P++R S + LAHP+ F D+
Sbjct: 296 IRQLPTL---PRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALAHPYLSSFHDIT 352
Query: 324 NE 325
+E
Sbjct: 353 DE 354
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 155 bits (393), Expect = 7e-38
Identities = 101/299 (33%), Positives = 160/299 (52%), Gaps = 22/299 (7%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
K IG+GA+G V + + N++ AIKK+ E + REL++LR H NV
Sbjct: 36 KPIGRGAYGVVCSSINSETNER----VAIKKIHNVFENRIDALRTLRELKLLRHVRHENV 91
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L+ + PT ++ + + + E++ +++ + K++ L H K + +Q+ RG+
Sbjct: 92 ISLKDV---MLPTHRYSFRDVYL--VYELMDSDLNQIIKSSQSLSDDHCKYFLFQLLRGL 146
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
YLH+ I HRD+KP N+LV+ LKICDFG A+ E Q Y+ +R+YRAPEL++
Sbjct: 147 KYLHSANILHRDLKPGNLLVNANCD-LKICDFGLARTYE--QFMTEYVVTRWYRAPELLL 203
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPDKRFIFFSNPSY 263
C Y T ID+W +GC+ E+L K +F G + L QL I ++G D F N
Sbjct: 204 CCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQDWDLQFIDNQKA 263
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
+ S P +G F + +A P +DLL +LV++P +R S L HP+ + L
Sbjct: 264 RRFIKSLPFSKG---THFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDALLHPYMEGL 319
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 154 bits (388), Expect = 3e-37
Identities = 91/298 (30%), Positives = 156/298 (51%), Gaps = 19/298 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
IG+GA+G V A + N+ AIKK+ + K RE+++LR DH N+V
Sbjct: 69 IGKGAYGIVCSAMNSETNES----VAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVA 124
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+ I P + + + E++ ++ + ++N L +H + + YQI RG+ Y
Sbjct: 125 IRDI---IPPPLRNAFNDVYIAY--ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKY 179
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ + HRD+KPSN+L++ LKICDFG A+ + Y+ +R+YRAPEL++
Sbjct: 180 IHSANVLHRDLKPSNLLLNANCD-LKICDFGLARVTSESDFMTEYVVTRWYRAPELLLNS 238
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGP 266
+ YT ID+W +GC+ E++ K +F G + QL + +L+G P + + F N +
Sbjct: 239 SDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENAKRY 298
Query: 267 LFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRN 324
+ P + P+ F P +DL+ +L ++P RR + LAHP+ + L +
Sbjct: 299 IRQLPPY---PRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPYLNSLHD 353
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 154 bits (388), Expect = 3e-37
Identities = 111/331 (33%), Positives = 171/331 (51%), Gaps = 34/331 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADHPNVVK 86
+GQGA+G V +A + + K AIKK+ P Q+ + REL +L+ DH NV+
Sbjct: 30 VGQGAYGQVCKAVVRGTSTK----VAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIG 85
Query: 87 LEYFYTHISPTDH--KLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
L + P D + Q + L + N I+R +K L HV+ YQI RG+
Sbjct: 86 LLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQK----LSDDHVQFLVYQILRGL 141
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
Y+H+ G+ HRD+KPSN+ V+ L+I DFG A+ ES Y+ +R+YRAPE+++
Sbjct: 142 KYIHSAGVIHRDLKPSNIAVNEDCE-LRILDFGLARPAESEMTG--YVATRWYRAPEIML 198
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIF-FSNPSY 263
Y DIW +GC++ E+L G+ +F G + QL+ I ++LG P F+ S+ S
Sbjct: 199 NWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESA 258
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLR 323
+ S P+ P+ F F A P +DLL +L + ++R + + LAHP+
Sbjct: 259 RNYIRSLPVM---PRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYM---- 311
Query: 324 NERYFFPSGSSQPKHLPPLYD--FSDFELQV 352
E+Y P+ + LYD F + EL V
Sbjct: 312 -EKYHDPT----DEQTAALYDQSFEENELPV 337
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 153 bits (386), Expect = 4e-37
Identities = 103/309 (33%), Positives = 167/309 (53%), Gaps = 27/309 (8%)
Query: 27 VKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIAD 80
V+ + IG GAFG VV A P + + + A+KK+P ++ REL++L
Sbjct: 40 VQPDRPIGYGAFG-VVWAVTDPRDGRRV---ALKKLPNVFQSLVSSKRVFRELKMLCFFK 95
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H NV+ + P +Q + + + E+LQ+++ + + L H+K++ YQI
Sbjct: 96 HENVLSA---LDILQPPHLDFFQEIYV--ITELLQSDLHKIIVSPQHLSADHIKVFLYQI 150
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS--ISYICSRYYR 198
RG+ YLH+ I HRDIKP N+LV+ +LKICDFG A+ E +Q + ++YYR
Sbjct: 151 LRGLKYLHSARILHRDIKPGNLLVNSNC-VLKICDFGLARVEEPDQAKHMTQEVVTQYYR 209
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFF 258
APE+++G Y++ +D+W +GC+ GE+L + +FQ P+ QL IT+LLG P +
Sbjct: 210 APEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRH 269
Query: 259 SNPSYNGPLFSKPLFEGAPK-ARFEKYF---GYAGPDGVDLLMSVLVYEPERRASPRRIL 314
+ + + APK F + +A + V LL +LV++P++R S L
Sbjct: 270 ACEGARTHMLRR-----APKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDAL 324
Query: 315 AHPFFDDLR 323
AHP+ D+ R
Sbjct: 325 AHPYLDEGR 333
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 151 bits (382), Expect = 1e-36
Identities = 100/304 (32%), Positives = 165/304 (53%), Gaps = 25/304 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+G+G++G V A + ++ AIKK+ E+ S RE+++LR+ HP+VV+
Sbjct: 110 VGKGSYGVVASAVDSHTGER----VAIKKINDVFEHVSDATRILREIKLLRLLRHPDVVE 165
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+++ + P + ++ + + + E++++++ + K N +L +H + + YQ+ RG+ Y
Sbjct: 166 IKHI---MLPPSRREFRDIYV--VFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKY 220
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS----ISYICSRYYRAPEL 202
+HA + HRD+KP N+L + LKICDFG A+ ++ P+ Y+ +R+YRAPEL
Sbjct: 221 VHAANVFHRDLKPKNILANADCK-LKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPEL 279
Query: 203 IVG-CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPDKRFIFFSN 260
++YT IDIW +GC+ EMLLGK +F G + QL +T LG PP + N
Sbjct: 280 CGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESISRIRN 339
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
L S + P F F A P + LL +L ++P+ RAS LA P+F
Sbjct: 340 EKARRYLSSMRKKQPVP---FSHKFPKADPLALRLLERLLAFDPKDRASAEDALADPYFS 396
Query: 321 DLRN 324
L N
Sbjct: 397 GLSN 400
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 151 bits (381), Expect = 2e-36
Identities = 106/303 (34%), Positives = 154/303 (49%), Gaps = 47/303 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADHPNVVK 86
+G GAFG V A T +Q P AIKK+ P T + REL++L+ H N++
Sbjct: 29 VGMGAFGLVCSATDTLTSQ----PVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLIC 84
Query: 87 LE----------YFYTHISPTD-HKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKL 135
L+ YF T + TD H+L Q +E + V+
Sbjct: 85 LQDIFLSPLEDIYFVTELQGTDLHRLLQTRPLE---------------------KQFVQY 123
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSR 195
+ YQI RG+ Y+H+ G+ HRD+KPSN+L++ LKICDFG A+ + Y+ +R
Sbjct: 124 FLYQILRGLKYVHSAGVIHRDLKPSNILINENCD-LKICDFGLARIQDPQMTG--YVSTR 180
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
YYRAPE+++ +Y ++DIW GC+ EM+ GK +F G + Q IT LLG P K
Sbjct: 181 YYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD- 239
Query: 256 IFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
+ + S N F L P F + F PD VDLL +LV++P++R + LA
Sbjct: 240 VINTICSENTLKFVTSLPHRDP-IPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALA 298
Query: 316 HPF 318
HP+
Sbjct: 299 HPY 301
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 151 bits (381), Expect = 2e-36
Identities = 89/299 (29%), Positives = 156/299 (51%), Gaps = 20/299 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG+GA+G V T N+ A+KK+ + RE+++LR DH N++
Sbjct: 44 IGRGAYGIVCSVLDTETNEL----VAMKKIANAFDNHMDAKRTLREIKLLRHLDHENIIA 99
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+ + P + + + + E++ ++ + ++N L +H + + YQ+ RG+ Y
Sbjct: 100 IRDV---VPPPLRRQFSDVYIST--ELMDTDLHQIIRSNQSLSEEHCQYFLYQLLRGLKY 154
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ I HRD+KPSN+L++ LKICDFG A+ N Y+ +R+YRAPEL++
Sbjct: 155 IHSANIIHRDLKPSNLLLNANCD-LKICDFGLARPTSENDFMTEYVVTRWYRAPELLLNS 213
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFS-NPSYNG 265
+ YT ID+W +GC+ E++ K +F G + Q+ +T+LLG P + + F+ N
Sbjct: 214 SDYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDLGFTHNEDAKR 273
Query: 266 PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRN 324
+ P F P+ K F + P +DL+ +L ++P RR + + L H + L +
Sbjct: 274 YIRQLPNF---PRQPLAKLFSHVNPMAIDLVDRMLTFDPNRRITVEQALNHQYLAKLHD 329
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 151 bits (381), Expect = 2e-36
Identities = 101/302 (33%), Positives = 155/302 (50%), Gaps = 25/302 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
K IG+GA+G V + + N+K AIKK+ E + REL++LR H NV
Sbjct: 36 KPIGRGAYGVVCSSVNSDTNEK----VAIKKIHNVYENRIDALRTLRELKLLRHLRHENV 91
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L+ I K + + E++ ++ + K++ L H + + +Q+ RG+
Sbjct: 92 IALKDVMMPIHKMSFK-----DVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGL 146
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRYYRAPELI 203
Y+H+ I HRD+KP N+LV+ LKICDFG A+ + Q Y+ +R+YRAPEL+
Sbjct: 147 KYIHSANILHRDLKPGNLLVNANCD-LKICDFGLARASNTKGQFMTEYVVTRWYRAPELL 205
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP-DKRFIFFSNPS 262
+ C Y T ID+W +GC+ E+L K +FQG + L QL I +LG ++ F NP
Sbjct: 206 LCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREEDLEFIDNPK 265
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPD--GVDLLMSVLVYEPERRASPRRILAHPFFD 320
+ S P G +R Y G +DLL +LV++P +R S L HP+
Sbjct: 266 AKRYIRSLPYSPGMSLSRL-----YPGAHVLAIDLLQKMLVFDPSKRISVSEALQHPYMA 320
Query: 321 DL 322
L
Sbjct: 321 PL 322
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 150 bits (380), Expect = 2e-36
Identities = 97/310 (31%), Positives = 164/310 (52%), Gaps = 19/310 (6%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEI 75
++++ ++ + IG GAFG V D ++ A+KK+P + REL++
Sbjct: 121 QQQLDIEPDRPIGYGAFGVVWSVTDPRDGKR----VALKKMPNVFQNLVSCKRVFRELKM 176
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKL 135
L H NV+ + P ++ + + + E++Q+++ + + L HVK+
Sbjct: 177 LCFFKHDNVLSA---LDILQPPHIDYFEEIYV--VTELMQSDLHKIIVSPQPLSSDHVKV 231
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYIC 193
+ YQI RG+ YLH+ GI HRDIKP N+LV+ +LKICDFG A+ +L+ ++ +
Sbjct: 232 FLYQILRGLKYLHSAGILHRDIKPGNLLVNSNC-VLKICDFGLARVEELDESRHMTQEVV 290
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDK 253
++YYRAPE+++G Y+ IDIW +GC+ E+L + +FQ P+ QL IT LLG P
Sbjct: 291 TQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSL 350
Query: 254 RFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRI 313
+ + + P + + + A + V LL +LV++P +R S +
Sbjct: 351 EAMRTACEGAKAHILRGPHKQPSLPVLY-TLSSQATHEAVHLLCRMLVFDPSKRISAKDA 409
Query: 314 LAHPFFDDLR 323
LAHP+ D+ R
Sbjct: 410 LAHPYLDEGR 419
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 150 bits (380), Expect = 2e-36
Identities = 97/307 (31%), Positives = 158/307 (50%), Gaps = 26/307 (8%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILR-IA 79
++ +++G+G +G V +A +K G A+KK + + RE+ ILR +A
Sbjct: 15 EKLEKVGEGTYGKVYRA-----REKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLA 69
Query: 80 DHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQ 139
P+VV+L +S + K +L E + ++ I ++ +P + +K YQ
Sbjct: 70 RDPHVVRLMDVKQGLSK-EGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSLMYQ 128
Query: 140 IARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYR 198
+ +GM + H GI HRD+KP N+L+DP+T LKI D G A+ ++ I + +YR
Sbjct: 129 LCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTLPMKKYTHEILTLWYR 188
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF--- 255
APE+++G T Y+T +D+W +GC+ E++ +A+FQG L QL I KL G P++
Sbjct: 189 APEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPG 248
Query: 256 IFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
+ + P + A E GVDLL +L YEP +R S + +
Sbjct: 249 VSTLKNWHEYPQWKPSTLSSAVPNLDEA--------GVDLLSKMLQYEPAKRISAKMAME 300
Query: 316 HPFFDDL 322
HP+FDDL
Sbjct: 301 HPYFDDL 307
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 150 bits (379), Expect = 3e-36
Identities = 103/304 (33%), Positives = 159/304 (51%), Gaps = 27/304 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG GAFG VV + P + K + A+KK+P A + RE+++L H NV+
Sbjct: 49 IGYGAFG-VVWSVTDPRSGKRV---ALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLS 104
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L + P + +Q L + L E++Q+++ + + L HVK++ YQI RG+ Y
Sbjct: 105 L---LDILQPANPSFFQELYV--LTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKY 159
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQP--SISYICSRYYRAPELIV 204
LH I HRDIKP N+LV+ ILKICDFG A+ + + ++YYRAPEL++
Sbjct: 160 LHTANILHRDIKPGNLLVNSNC-ILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLM 218
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G +YT +DIW +GC+ E+L K +FQ P+ QL I LLG P + + ++
Sbjct: 219 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 278
Query: 265 GPLFSKPLFEGAPKARFEKYFGYAGPD-----GVDLLMSVLVYEPERRASPRRILAHPFF 319
+ L G ++ + A PD VDLL +L ++P++R S L H +
Sbjct: 279 NHV----LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYL 334
Query: 320 DDLR 323
++ R
Sbjct: 335 EEGR 338
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 150 bits (379), Expect = 3e-36
Identities = 103/304 (33%), Positives = 159/304 (51%), Gaps = 27/304 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG GAFG VV + P + K + A+KK+P A + RE+++L H NV+
Sbjct: 74 IGYGAFG-VVWSVTDPRSGKRV---ALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLS 129
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L + P + +Q L + L E++Q+++ + + L HVK++ YQI RG+ Y
Sbjct: 130 L---LDILQPANPSFFQELYV--LTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKY 184
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQP--SISYICSRYYRAPELIV 204
LH I HRDIKP N+LV+ ILKICDFG A+ + + ++YYRAPEL++
Sbjct: 185 LHTANILHRDIKPGNLLVNSNC-ILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLM 243
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G +YT +DIW +GC+ E+L K +FQ P+ QL I LLG P + + ++
Sbjct: 244 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 303
Query: 265 GPLFSKPLFEGAPKARFEKYFGYAGPD-----GVDLLMSVLVYEPERRASPRRILAHPFF 319
+ L G ++ + A PD VDLL +L ++P++R S L H +
Sbjct: 304 NHV----LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYL 359
Query: 320 DDLR 323
++ R
Sbjct: 360 EEGR 363
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 150 bits (379), Expect = 3e-36
Identities = 103/304 (33%), Positives = 159/304 (51%), Gaps = 27/304 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG GAFG VV + P + K + A+KK+P A + RE+++L H NV+
Sbjct: 246 IGYGAFG-VVWSVTDPRSGKRV---ALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLS 301
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L + P + +Q L + L E++Q+++ + + L HVK++ YQI RG+ Y
Sbjct: 302 L---LDILQPANPSFFQELYV--LTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKY 356
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQP--SISYICSRYYRAPELIV 204
LH I HRDIKP N+LV+ ILKICDFG A+ + + ++YYRAPEL++
Sbjct: 357 LHTANILHRDIKPGNLLVNSNC-ILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLM 415
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G +YT +DIW +GC+ E+L K +FQ P+ QL I LLG P + + ++
Sbjct: 416 GARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAK 475
Query: 265 GPLFSKPLFEGAPKARFEKYFGYAGPD-----GVDLLMSVLVYEPERRASPRRILAHPFF 319
+ L G ++ + A PD VDLL +L ++P++R S L H +
Sbjct: 476 NHV----LRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYL 531
Query: 320 DDLR 323
++ R
Sbjct: 532 EEGR 535
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 150 bits (379), Expect = 3e-36
Identities = 100/307 (32%), Positives = 164/307 (52%), Gaps = 31/307 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
IG+G++G V A T +K AIKK+ E+ S RE+++LR+ HP++V+
Sbjct: 132 IGKGSYGVVASAIDTHSGEK----VAIKKINDVFEHVSDATRILREIKLLRLLRHPDIVE 187
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+++ + P + ++ + + + E++++++ + K N +L +H + + YQ+ RG+ +
Sbjct: 188 IKHV---MLPPSRREFRDIYV--VFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKF 242
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI----SYICSRYYRAPEL 202
+H + HRD+KP N+L + LKICDFG A+ ++ PS Y+ +R+YRAPEL
Sbjct: 243 IHTANVFHRDLKPKNILANSDCK-LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPEL 301
Query: 203 IVGC-TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPDKRFIFFSN 260
++YT IDIW +GC+ EML GK +F G + QL +T LLG PP + N
Sbjct: 302 CGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEAIARIRN 361
Query: 261 PS---YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
Y G + K P F F + P + LL +L ++P+ R S LA P
Sbjct: 362 EKARRYLGNMRRK------PPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPSAEEALADP 415
Query: 318 FFDDLRN 324
+F L N
Sbjct: 416 YFYGLAN 422
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 149 bits (377), Expect = 5e-36
Identities = 100/291 (34%), Positives = 156/291 (53%), Gaps = 23/291 (7%)
Query: 33 IGQGAFGTVVQA--YLTPDN---QKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKL 87
IG GAFG V A LT N +K + PF+ P + REL++L+ H N++ L
Sbjct: 26 IGMGAFGLVCSAKDQLTGMNVAVKKIMKPFS---TPVLAKRTYRELKLLKHLRHENIISL 82
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+ ISP + + + E+L ++ R + L + ++ + YQI RG+ ++
Sbjct: 83 SDIF--ISPFEDIYF-------VTELLGTDLHRLLTSR-PLETQFIQYFLYQILRGLKFV 132
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCT 207
H+ G+ HRD+KPSN+L++ LKICDFG A+ + Y+ +RYYRAPE+++
Sbjct: 133 HSAGVIHRDLKPSNILINENCD-LKICDFGLARIQDPQMTG--YVSTRYYRAPEIMLTWQ 189
Query: 208 QYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPL 267
+Y ++DIW GC+ EM+ GK +F G + Q IT+LLG P + + S N
Sbjct: 190 KYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPME-VIETICSKNTLR 248
Query: 268 FSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
F + L + K F + F A PD +DLL +LV++P +R S LAH +
Sbjct: 249 FVQSLPQ-KEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADALAHNY 298
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 149 bits (376), Expect = 6e-36
Identities = 107/338 (31%), Positives = 175/338 (51%), Gaps = 34/338 (10%)
Query: 26 LVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIA 79
+ ++ + +G GA+G V +A + N AIKK+ P Q+ + REL +L+
Sbjct: 24 IYQDLQPVGSGAYGQVSKAVVRGTNMH----VAIKKLARPFQSAVHAKRTYRELRLLKHM 79
Query: 80 DHPNVVKL-EYFYTHISPTDHKLYQHLAMEC-LPEMLQNEILRYKKNNLELPLKHVKLYA 137
DH NV+ L + F+ H + + +Q + + L + N I+R + L HV+
Sbjct: 80 DHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQ----HLSDDHVQFLV 135
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYY 197
YQI RG+ Y+H+ G+ HRD+KPSN+ V+ L+I DFG A+ E+ Y+ +R+Y
Sbjct: 136 YQILRGLKYIHSAGVIHRDLKPSNIAVNEDCE-LRILDFGLARPTENEMTG--YVATRWY 192
Query: 198 RAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI- 256
RAPE+++ Y +DIW +GC++ E++ + +F G + QL+ I ++LG P F+
Sbjct: 193 RAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLK 252
Query: 257 FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAH 316
S+ S + S P +G F+ F A P +DLL +L + E+R + L+H
Sbjct: 253 KISSESARSYIQSLPPMKG---RSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSH 309
Query: 317 PFFDDLRNERYFFPSGSSQPKHLPPLYD--FSDFELQV 352
P+ E+Y PS + P YD F D +L V
Sbjct: 310 PYL-----EKYAEPS----VEQTSPPYDHSFEDMDLPV 338
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 149 bits (375), Expect = 8e-36
Identities = 97/320 (30%), Positives = 168/320 (52%), Gaps = 19/320 (5%)
Query: 9 YVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP----- 63
YV ++V+ N + + + + IG+GA+G V A + N++ AIKK+
Sbjct: 16 YVMYNVLGNIFELSSKY-IPPIEPIGRGAYGIVCCATNSETNEE----VAIKKIANAFDN 70
Query: 64 -AQTEYKSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYK 122
+ RE+++L DH NV+K++ I + + ++ + + + E++ ++ +
Sbjct: 71 RVDAKRTLREIKLLSHMDHDNVIKIKDI---IELPEKERFEDVYI--VYELMDTDLHQII 125
Query: 123 KNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL 182
++ L H + + YQI RG+ Y+H+ + HRD+KPSN++++ LKICDFG A+
Sbjct: 126 RSTQTLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCD-LKICDFGLARTS 184
Query: 183 ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH 242
+ Y+ +R+YRAPEL++ ++YT IDIW +GC+ E+L + +F G + QL
Sbjct: 185 NETEIMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLK 244
Query: 243 EITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
IT+LLG PD + F S N + K L K F + F P +DL +LV+
Sbjct: 245 LITELLGSPDDSDLDFLR-SDNARKYVKQL-PHVQKQSFREKFPNISPMALDLAEKMLVF 302
Query: 303 EPERRASPRRILAHPFFDDL 322
+P +R + L P+ L
Sbjct: 303 DPSKRITVDEALKQPYLASL 322
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 148 bits (373), Expect = 1e-35
Identities = 103/308 (33%), Positives = 161/308 (51%), Gaps = 30/308 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADH 81
++ + +G GA+G V A K AIKK+ P Q+E + REL +L+ H
Sbjct: 28 RDLQPVGSGAYGAVCSAVDGRTGAK----VAIKKLYRPFQSELFAKRAYRELRLLKHMRH 83
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
NV+ L +T D +L M + L ++++++K L ++ YQ+
Sbjct: 84 ENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDL-GKLMKHEK----LGEDRIQFLVYQML 138
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPE 201
+G+ Y+HA GI HRD+KP N+ V+ LKI DFG A++ +S Y+ +R+YRAPE
Sbjct: 139 KGLRYIHAAGIIHRDLKPGNLAVNEDCE-LKILDFGLARQADSEMTG--YVVTRWYRAPE 195
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--FFS 259
+I+ +YT +DIW +GC++ EM+ GK +F+G L QL EI K+ G P F+ S
Sbjct: 196 VILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQS 255
Query: 260 NPSYNGPLFSKPLFEGAP---KARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAH 316
+ + N +G P K F A P V+LL +LV + E+R + LAH
Sbjct: 256 DEAKNN-------MKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAH 308
Query: 317 PFFDDLRN 324
P+F+ L +
Sbjct: 309 PYFESLHD 316
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 148 bits (373), Expect = 1e-35
Identities = 99/300 (33%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
K IG+GA+G V + N++ AIKK+ E + REL++LR H NV
Sbjct: 36 KPIGRGAYGVVCSSVNRESNER----VAIKKIHNVFENRIDALRTLRELKLLRHLRHENV 91
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
V L+ + +HK + + E++ ++ + K++ L H + + +Q+ RG+
Sbjct: 92 VALK----DVMMANHKR-SFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGL 146
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRYYRAPELI 203
Y+H+ I HRD+KP N+LV+ LKICDFG A+ + Q Y+ +R+YRAPEL+
Sbjct: 147 KYIHSANILHRDLKPGNLLVNANCD-LKICDFGLARTSNTKGQFMTEYVVTRWYRAPELL 205
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP-DKRFIFFSNPS 262
+ C Y T ID+W +GC+ E+L K VF G + L Q+ I +LG ++ F NP
Sbjct: 206 LCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREEDLEFIDNPK 265
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
+ S P +P F + + A +DLL +LV +P +R S L HP+ L
Sbjct: 266 AKRYIESLPY---SPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPYMAPL 322
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 147 bits (372), Expect = 2e-35
Identities = 97/305 (31%), Positives = 167/305 (53%), Gaps = 25/305 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+G+G++G V A T ++ AIKK+ ++ S RE+++LR+ HP+VV+
Sbjct: 96 VGKGSYGVVGSAIDTHTGER----VAIKKINDVFDHISDATRILREIKLLRLLLHPDVVE 151
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+++ + P + ++ + + + E++++++ + K N +L +H + + YQ+ RG+ Y
Sbjct: 152 IKHI---MLPPSRREFRDVYV--VFELMESDLHQVIKANDDLTPEHHQFFLYQLLRGLKY 206
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI----SYICSRYYRAPEL 202
+HA + HRD+KP N+L + LKICDFG A+ ++ P+ Y+ +R+YRAPEL
Sbjct: 207 VHAANVFHRDLKPKNILANADCK-LKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPEL 265
Query: 203 IVGC-TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPDKRFIFFSN 260
++YT IDIW +GC+ EMLLGK +F G + QL +T LG PP + N
Sbjct: 266 CGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAISKIRN 325
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
L + + P F K F A P + LL ++ ++P+ R S LA P+F+
Sbjct: 326 DKARRYLGNMRKKQPVP---FSKKFPKADPSALRLLERLIAFDPKDRPSAEEALADPYFN 382
Query: 321 DLRNE 325
L ++
Sbjct: 383 GLSSK 387
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 147 bits (371), Expect = 2e-35
Identities = 104/331 (31%), Positives = 166/331 (49%), Gaps = 25/331 (7%)
Query: 1 MSMQRLDEYVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIK 60
MS+ R + DV NK+ + +G GA+G+V A +K AIK
Sbjct: 1 MSLIRKKGFYKQDV--NKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEK----VAIK 54
Query: 61 KV--PAQTEYKS----RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEML 114
K+ P Q+E + REL +L+ H NV+ L +T S + +L M + L
Sbjct: 55 KLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDL 114
Query: 115 QNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKIC 174
Q K +E + ++ YQ+ +G+ Y+H+ G+ HRD+KP N+ V+ LKI
Sbjct: 115 Q------KIMGMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCE-LKIL 167
Query: 175 DFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQG 234
DFG A+ ++ Y+ +R+YRAPE+I+ Y +DIW +GC++ EML GK +F+G
Sbjct: 168 DFGLARHADAEMTG--YVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKG 225
Query: 235 HQPLLQLHEITKLLGPPDKRFI-FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV 293
L QL +I K+ G P F+ ++ + + S P P+ F + F A P
Sbjct: 226 KDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLP---QTPRKDFTQLFPRASPQAA 282
Query: 294 DLLMSVLVYEPERRASPRRILAHPFFDDLRN 324
DLL +L + ++R + + L HPFF+ R+
Sbjct: 283 DLLEKMLELDVDKRLTAAQALTHPFFEPFRD 313
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 147 bits (371), Expect = 2e-35
Identities = 96/304 (31%), Positives = 158/304 (51%), Gaps = 27/304 (8%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ ++IG+G +G V +A N+ A+KK+ + E + RE+ +L+ H
Sbjct: 5 EKVEKIGEGTYGVVYKARDKVTNET----IALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
N+VK Y + ++ +LY L E L L+ + + +L + +K Y YQI
Sbjct: 61 SNIVK----YDDVVHSEKRLY--LVFEYLDLDLKKHMDSTPDFSKDLHM--IKTYLYQIL 112
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRAP 200
RG+ Y H+ + HRD+KP N+L+D +T LK+ DFG A+ + ++ + + +YRAP
Sbjct: 113 RGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAP 172
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP--DKRFIFF 258
E+++G Y+T +DIW +GC+ EM+ K +F G + QL +I +++G P D
Sbjct: 173 EILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVT 232
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
S P Y K F E + PDGVDLL +L+ +P +R + R L H +
Sbjct: 233 SLPDY------KSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEY 286
Query: 319 FDDL 322
F DL
Sbjct: 287 FKDL 290
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 147 bits (370), Expect = 3e-35
Identities = 94/305 (30%), Positives = 161/305 (51%), Gaps = 32/305 (10%)
Query: 26 LVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIA 79
+ ++ ++IG+G +G V +A N++ A+KK+ E + RE+ +L+
Sbjct: 3 MFQKVEKIGEGTYGVVYKA----KNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKEL 58
Query: 80 DHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNN--LELPLKHVKLYA 137
HPN+V+L + + KLY + E L ++ +Y + ELPL +K Y
Sbjct: 59 KHPNIVRL----LDVVHNERKLY------LVFEFLSQDLKKYMDSTPGSELPLHLIKSYL 108
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRY 196
+Q+ +G+ + H+ + HRD+KP N+L++ + G +K+ DFG A+ + ++ + + +
Sbjct: 109 FQLLQGVSFCHSHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTLW 167
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP--DKR 254
YRAPE+++G YTT +DIW +GC+ EM+ KA+F G + QL I ++LG P D
Sbjct: 168 YRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTW 227
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
P Y G F + E+ P+G DLLM +L Y+P +R + + L
Sbjct: 228 PGVTQLPDYKGS------FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTAL 281
Query: 315 AHPFF 319
AHP+F
Sbjct: 282 AHPYF 286
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 145 bits (365), Expect = 1e-34
Identities = 93/311 (29%), Positives = 162/311 (51%), Gaps = 33/311 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRI-ADHPNVV 85
+G+GA+GTV + A+KK+ + REL+ + H N+V
Sbjct: 44 LGKGAYGTVCSVKFK--GRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIV 101
Query: 86 KL-EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
L + SP D + C E++ ++ + ++++L H+K + YQI G+
Sbjct: 102 NLIDLEIVTSSPYD-------GLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGL 154
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN--------QPSIS-YICSR 195
Y+H+ + HRD+KP N+L G LKICDFG A+ + + QP I+ Y+ +R
Sbjct: 155 KYIHSADVIHRDLKPGNILCT-LNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATR 213
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
+YRAPEL++ Y+ +DIW +GC+L E K VF G + Q+ EI K+LG PDK
Sbjct: 214 WYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDI 273
Query: 256 I--FFSNPSYN-GPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
+ F + ++N G + P+++ P + F +A + ++L+ S+L ++ R + +
Sbjct: 274 LIKFGTIKAWNLGKNSNNPVYKKIP---WSNIFPFASHEAINLIESLLHWDSTHRLNVEQ 330
Query: 313 ILAHPFFDDLR 323
++HPF +++R
Sbjct: 331 AISHPFLNEVR 341
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 144 bits (364), Expect = 2e-34
Identities = 108/345 (31%), Positives = 171/345 (49%), Gaps = 35/345 (10%)
Query: 26 LVKEYKRI---GQGAFGTVVQAYLTPDNQKWLGPFAIKKV-----PAQTEYKSRELEILR 77
L +EY+ I GQGA+G V A P K A+KK+ P RE+++LR
Sbjct: 35 LPEEYEMINLIGQGAYGVVCAALHKPSGLK----VAVKKIHPFNHPVFCLRTLREIKLLR 90
Query: 78 IADHPNVVKLEYFYTHISPTDHKLYQHLA-MECLPEMLQNEILRYKKNNLELPLKHVKLY 136
H N++ + I P YQ L + + E+++ ++ R ++ L H + +
Sbjct: 91 HFRHENIISI----LDILPPPS--YQELEDVYIVQELMETDLYRVIRSQ-PLSDDHCQYF 143
Query: 137 AYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL--ESNQPSI--SYI 192
YQI R + +H+ G+ HRD+KPSN+L++ LK+ DFG A+ + P Y+
Sbjct: 144 TYQILRALKAMHSAGVVHRDLKPSNLLLNANCD-LKVADFGLARSTTAQGGNPGFMTEYV 202
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+R+YRAPE+++ +Y+ ID+W GC+L EML + +F G Q+ I +LG P
Sbjct: 203 ATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPT 262
Query: 253 KRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
F S + K L PK F+ F A PD +DLL +L + P++R +
Sbjct: 263 MD-DFSRIKSARARKYIKSL-PFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEE 320
Query: 313 ILAHPF---FDDLRNERYFFPSGSSQPKHLPPLY-DFSDFELQVI 353
L HP+ + D +E P+ S P +L LY + D E+ V+
Sbjct: 321 ALKHPYVAAYHDASDE----PTASPMPPNLVDLYCNKEDLEIPVL 361
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 144 bits (363), Expect = 2e-34
Identities = 96/302 (31%), Positives = 161/302 (52%), Gaps = 25/302 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
IG+G++G V AY T +K AIKK+ E+ S RE+++LR+ HP++V+
Sbjct: 31 IGKGSYGVVCSAYDTHTGEK----VAIKKINDIFEHVSDATRILREIKLLRLLRHPDIVE 86
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+++ + P + ++ + + + E++++++ + K N +L +H + + YQ+ RG+ Y
Sbjct: 87 IKHI---LLPPSRREFRDIYV--VFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKY 141
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS----ISYICSRYYRAPEL 202
+H + HRD+KP N+L + LKICDFG A+ ++ P+ Y+ +R+YRAPEL
Sbjct: 142 IHTANVFHRDLKPKNILANADCK-LKICDFGLARVAFNDTPTAIFWTDYVATRWYRAPEL 200
Query: 203 IVG-CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSN 260
++YT IDIW +GC+ E+L GK +F G + QL +T +LG P I N
Sbjct: 201 CGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAIGRVRN 260
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
L S + P F F + P + LL +L +EP+ R + LA +F
Sbjct: 261 EKARRYLSSMRKKKPIP---FSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALADVYFK 317
Query: 321 DL 322
L
Sbjct: 318 GL 319
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 144 bits (363), Expect = 2e-34
Identities = 97/300 (32%), Positives = 156/300 (51%), Gaps = 27/300 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
IG+G++G V A T +K AIKK+ E+ S RE+++LR+ HP++V+
Sbjct: 19 IGKGSYGVVCAAIDTQTGEK----VAIKKINDVFEHVSDALRILREVKLLRLLRHPDIVE 74
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
++ S + K + + E++++++ + K N +L +H + + YQ+ R + Y
Sbjct: 75 IKSIMLPPSKREFK-----DIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRALKY 129
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI----SYICSRYYRAPEL 202
+H + HRD+KP N+L + LK+CDFG A+ ++ P+ Y+ +R+YRAPEL
Sbjct: 130 MHTANVYHRDLKPKNILANANCK-LKVCDFGLARVSFNDTPTTVFWTDYVATRWYRAPEL 188
Query: 203 IVG-CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNP 261
C++YT IDIW +GC+ E+L GK +F G + QL IT LLG P I
Sbjct: 189 CGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETI----A 244
Query: 262 SYNGPLFSKPLFEGAPK--ARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
K L E K F + F A P + LL +L ++P+ R + LA P+F
Sbjct: 245 GVRNEKARKYLNEMRKKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADPYF 304
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 144 bits (363), Expect = 2e-34
Identities = 95/307 (30%), Positives = 161/307 (51%), Gaps = 26/307 (8%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILR-IA 79
++ +++G+G +G V +A +K G A+KK + + RE+ ILR +A
Sbjct: 17 EKLEKVGEGTYGKVYRA-----REKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLA 71
Query: 80 DHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQ 139
P++V+L I+ + K +L E + L+ I +++ +P VK YQ
Sbjct: 72 RDPHIVRLMDVKQGINK-EGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQ 130
Query: 140 IARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYR 198
+ +GM + H G+ HRD+KP N+L+D +T LKI D G A+ ++ I + +YR
Sbjct: 131 LCKGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTLPMKKYTHEILTLWYR 190
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF--- 255
APE+++G T Y+T +D+W +GC+ E++ +A+F G L QL I +LLG P++
Sbjct: 191 APEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVWPG 250
Query: 256 IFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
+ + P + KPL ++ G+DLL +L YEP +R S ++ +
Sbjct: 251 VSKLKDWHEYPQW-KPLSLSTAVPNLDE-------AGLDLLSKMLEYEPAKRISAKKAME 302
Query: 316 HPFFDDL 322
HP+FDDL
Sbjct: 303 HPYFDDL 309
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 144 bits (362), Expect = 3e-34
Identities = 102/308 (33%), Positives = 155/308 (50%), Gaps = 29/308 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QT--EYKSRELEILRIADHPNVVKL 87
IG+GA+G V A T + AIKK+ QT + RE++IL H N++ +
Sbjct: 102 IGEGAYGMVASALDTITRDR----VAIKKISPFEHQTFCQRTLREIKILNRFKHENIINI 157
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+ S T L ++CL E ++L+ +K L HV + YQI RG+ Y+
Sbjct: 158 QEIIR--SETVDSLKDIYIVQCLMETDLYKLLKTQK----LSNDHVCYFLYQILRGLKYI 211
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS----YICSRYYRAPELI 203
H+ + HRD+KPSN+L++ T LKICDFG A+ + Y+ +R+YRAPE++
Sbjct: 212 HSANVLHRDLKPSNLLLNT-TCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEIM 270
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPS 262
+ YT ID+W +GC+L EML + +F G L QL+ I ++G P + N
Sbjct: 271 LNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDK 330
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
L S P PK + + + A P +DLL +L + P R + LAHP+
Sbjct: 331 ARSYLISLP---HKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYL--- 384
Query: 323 RNERYFFP 330
E+Y+ P
Sbjct: 385 --EQYYDP 390
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 144 bits (362), Expect = 3e-34
Identities = 102/308 (33%), Positives = 155/308 (50%), Gaps = 29/308 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QT--EYKSRELEILRIADHPNVVKL 87
IG+GA+G V A T + AIKK+ QT + RE++IL H N++ +
Sbjct: 34 IGEGAYGMVASALDTITRDR----VAIKKISPFEHQTFCQRTLREIKILNRFKHENIINI 89
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+ S T L ++CL E ++L+ +K L HV + YQI RG+ Y+
Sbjct: 90 QEIIR--SETVDSLKDIYIVQCLMETDLYKLLKTQK----LSNDHVCYFLYQILRGLKYI 143
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS----YICSRYYRAPELI 203
H+ + HRD+KPSN+L++ T LKICDFG A+ + Y+ +R+YRAPE++
Sbjct: 144 HSANVLHRDLKPSNLLLNT-TCDLKICDFGLARVTDPQTDHTGFLTEYVATRWYRAPEIM 202
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPS 262
+ YT ID+W +GC+L EML + +F G L QL+ I ++G P + N
Sbjct: 203 LNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCIINDK 262
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
L S P PK + + + A P +DLL +L + P R + LAHP+
Sbjct: 263 ARSYLISLP---HKPKQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYL--- 316
Query: 323 RNERYFFP 330
E+Y+ P
Sbjct: 317 --EQYYDP 322
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 143 bits (361), Expect = 3e-34
Identities = 95/303 (31%), Positives = 158/303 (51%), Gaps = 28/303 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKK--------VPAQTEYKSRELEILRIADHPNV 84
IG GA+GTV A T + AIKK + A+ Y REL +LR H N+
Sbjct: 41 IGTGAYGTVCAAECTRSGTR----VAIKKFNRPFQSIIHARRTY--RELRLLRCMCHENI 94
Query: 85 VKL-EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
+ L + F + + D + ++M ++ + IL+ ++ N + H++ YQI RG
Sbjct: 95 IDLLDVFTPNENVNDIEDVYFVSMLMGADL--SNILKIQRLNDD----HIQFLVYQILRG 148
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
+ Y+H+ I HRD+KPSN+ V+ LKI DFG A++ +S Y+ +R+YRAPE++
Sbjct: 149 LKYIHSADIIHRDLKPSNIAVNEDCE-LKILDFGLARQTDSEMTG--YVATRWYRAPEIM 205
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPS 262
+ YT +D+W +GC+L E++ GK +F G + QL I + G PD+ F+ S+
Sbjct: 206 LNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEE 265
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
+ + P + F++ F A P +DLL +L +P+RR + + + H +
Sbjct: 266 ARNYIRNLPKM---TRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAY 322
Query: 323 RNE 325
+E
Sbjct: 323 HDE 325
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 143 bits (361), Expect = 3e-34
Identities = 96/302 (31%), Positives = 161/302 (52%), Gaps = 25/302 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
IG+G++G V A T +K AIKK+ E+ S RE+++LR+ HP++V+
Sbjct: 19 IGKGSYGVVCSAIDTLTGEK----VAIKKIHDIFEHISDAARILREIKLLRLLRHPDIVE 74
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+++ + P + ++ + + + E++++++ + K N +L +H + + YQ+ R + Y
Sbjct: 75 IKHI---MLPPSRREFKDIYV--VFELMESDLHQVIKANDDLTREHYQFFLYQLLRALKY 129
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI----SYICSRYYRAPEL 202
+H + HRD+KP N+L + LKICDFG A+ ++ P+ Y+ +R+YRAPEL
Sbjct: 130 IHTANVYHRDLKPKNILANANCK-LKICDFGLARVAFNDTPTTIFWTDYVATRWYRAPEL 188
Query: 203 IVGC-TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIF-FSN 260
++YT IDIW +GC+ E+L+GK +F G + QL +T LLG P I N
Sbjct: 189 CGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRN 248
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
L S P F + F A P + LL +L ++P+ R + LA P+F
Sbjct: 249 EKARRYLTS---MRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPYFK 305
Query: 321 DL 322
L
Sbjct: 306 GL 307
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 143 bits (361), Expect = 3e-34
Identities = 96/303 (31%), Positives = 157/303 (51%), Gaps = 27/303 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
IG+G++G V A T +K AIKK+ E+ S RE+++LR+ HP++V+
Sbjct: 19 IGKGSYGVVCAAIDTHTGEK----VAIKKINDVFEHISDALRILREVKLLRLLRHPDIVE 74
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
++ S + K + + E++++++ + K N +L +H + + YQ+ R + +
Sbjct: 75 IKSIMLPPSKREFK-----DIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRALKF 129
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI----SYICSRYYRAPEL 202
+H + HRD+KP N+L + LK+CDFG A+ ++ P+ Y+ +R+YRAPEL
Sbjct: 130 MHTANVYHRDLKPKNILANANCK-LKVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPEL 188
Query: 203 IVGC-TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNP 261
++YT ID+W +GC+ E+L GK +F G + QL IT LLG P I
Sbjct: 189 CGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETI----S 244
Query: 262 SYNGPLFSKPLFEGAPK--ARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
K L E K F + F A P + LL +L ++P+ R +P LA P+F
Sbjct: 245 GVRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPYF 304
Query: 320 DDL 322
L
Sbjct: 305 KGL 307
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 142 bits (359), Expect = 6e-34
Identities = 97/322 (30%), Positives = 166/322 (51%), Gaps = 22/322 (6%)
Query: 9 YVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEY 68
Y ++V N V + V + IG+GA + L+ D++ AIKK+ +
Sbjct: 26 YFQYNVYGNLFEVSNKY-VPPIRPIGRGA------SVLSVDSETH-EEIAIKKIGKAFDN 77
Query: 69 KS------RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYK 122
K RE+++LR +H NVV ++ I P K + + + E++ ++ +
Sbjct: 78 KVDAKRTLREIKLLRHLEHENVVVIKDI---IRPP--KKEDFVDVYIVFELMDTDLHQII 132
Query: 123 KNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL 182
++N L H + + YQI RG+ Y+H+ + HRD+KPSN+L++ LKI DFG A+
Sbjct: 133 RSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCD-LKITDFGLARTT 191
Query: 183 ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH 242
+ Y+ +R+YRAPEL++ ++YT+ ID+W +GC+ E++ + +F G + QL
Sbjct: 192 SETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLK 251
Query: 243 EITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
IT+L+G PD + F S N + K L P+ F F +DLL +LV+
Sbjct: 252 LITELIGSPDGASLEFLR-SANARKYVKEL-PKFPRQNFSARFPSMNSTAIDLLEKMLVF 309
Query: 303 EPERRASPRRILAHPFFDDLRN 324
+P +R + L +P+ L +
Sbjct: 310 DPVKRITVEEALCYPYLSALHD 331
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 142 bits (359), Expect = 6e-34
Identities = 100/327 (30%), Positives = 171/327 (51%), Gaps = 31/327 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADH 81
++ ++IGQG + +V +A T + A+KKV P + +RE+ ILR +H
Sbjct: 132 EKLEKIGQGTYSSVFRARETETGRI----VALKKVRFDNFEPESVRFMAREILILRKLNH 187
Query: 82 PNVVKLEYFYTH-ISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
PN++KLE T +S + H +++++ + L +L + +++ +K Y Q+
Sbjct: 188 PNIIKLEGIVTSKLSCSIHLVFEYMEHD-LTGLLSSP-------DIDFTTPQIKCYMKQL 239
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN---QPSISYICSRYY 197
G+ + HA G+ HRDIK SN+LV+ + GILK+ DFG A ++ QP S + + +Y
Sbjct: 240 LSGLDHCHARGVMHRDIKGSNLLVNNE-GILKVADFGLANFCNASGNKQPLTSRVVTLWY 298
Query: 198 RAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIF 257
R PEL++G T+Y +D+W +GCV E+L+GK V QG + QLH+I KL G P + +
Sbjct: 299 RPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGSPPEDYWK 358
Query: 258 FSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL--- 314
S + + ++G + K G + D ++L+ ++L +P +R + L
Sbjct: 359 KSKLPHAMLFKPQQHYDGCLRETL-KLKGLSDAD-INLIETLLSIQPHKRGTASTALVSQ 416
Query: 315 ---AHPFFDDLRNERYFFPSGSSQPKH 338
+ PF D + + PS KH
Sbjct: 417 YFTSKPFACDPSSLPVYSPSKEIDAKH 443
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 142 bits (358), Expect = 8e-34
Identities = 96/293 (32%), Positives = 153/293 (51%), Gaps = 20/293 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADHPNVVK 86
+G GA+G+V A+ T + A+KK+ P Q+ + REL +L+ H NV+
Sbjct: 30 VGSGAYGSVCAAFDTKTGLR----VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIG 85
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L +T + +L + L N I++ +K L HV+ YQI RG+ Y
Sbjct: 86 LLDVFTPARSLEEFNDVYLVTHLMGADLNN-IVKCQK----LTDDHVQFLIYQILRGLKY 140
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ I HRD+KPSN+ V+ LKI DFG A+ + Y+ +R+YRAPE+++
Sbjct: 141 IHSADIIHRDLKPSNLAVNEDCE-LKILDFGLARHTDDEMTG--YVATRWYRAPEIMLNW 197
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGP 266
Y +DIW +GC++ E+L G+ +F G + QL +I +L G P ++ PS+
Sbjct: 198 MHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTP-PAYLINRMPSHEAR 256
Query: 267 LFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ + L + PK F F A P VDLL +LV + ++R + + LAH +F
Sbjct: 257 NYIQSLTQ-MPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF 308
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 141 bits (356), Expect = 1e-33
Identities = 93/336 (27%), Positives = 166/336 (48%), Gaps = 38/336 (11%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV-----PAQTEYKSRELEILRIADHPNVVKL 87
+G+GA+G V A P + AIKK+ P RE++IL+ H N++ +
Sbjct: 19 LGEGAYGVVCSATHKPTGEI----VAIKKIEPFDKPLFALRTLREIKILKHFKHENIITI 74
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+ P + + + + + E++Q ++ R + L H++ + YQ R + L
Sbjct: 75 ---FNIQRPDSFENFNEVYI--IQELMQTDLHRVISTQM-LSDDHIQYFIYQTLRAVKVL 128
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS-----------YICSRY 196
H + HRD+KPSN+L++ LK+CDFG A+ ++ + S Y+ +R+
Sbjct: 129 HGSNVIHRDLKPSNLLINSNCD-LKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRW 187
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP--DKR 254
YRAPE+++ +Y+ +D+W GC+L E+ L + +F G QL I ++G P D
Sbjct: 188 YRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDND 247
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
+P + S P++ AP EK F P G+DLL +LV++P +R + + L
Sbjct: 248 LRCIESPRAREYIKSLPMYPAAP---LEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEAL 304
Query: 315 AHPFFDDLRNERYFFPSGSSQPKHLPP-LYDFSDFE 349
HP+ + Y P+ + + +PP ++F ++
Sbjct: 305 EHPYL-----QTYHDPNDEPEGEPIPPSFFEFDHYK 335
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 141 bits (355), Expect = 2e-33
Identities = 99/309 (32%), Positives = 158/309 (51%), Gaps = 29/309 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QT--EYKSRELEILRIADHPNVVKL 87
IG+GA+G V AY + + AIKK+ QT + RE++IL H N++ +
Sbjct: 31 IGEGAYGMVCSAYDNVNKVR----VAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGI 86
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+PT + Q + + ++++ ++ + K L H+ + YQI RG+ Y+
Sbjct: 87 NDIIR--APT---IEQMKDVYIVQDLMETDLYKLLKTQ-HLSNDHICYFLYQILRGLKYI 140
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS----YICSRYYRAPELI 203
H+ + HRD+KPSN+L++ T LKICDFG A+ + + Y+ +R+YRAPE++
Sbjct: 141 HSANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIM 199
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPS 262
+ YT IDIW +GC+L EML + +F G L QL+ I +LG P + + N
Sbjct: 200 LNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLK 259
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
L S P P + + F A +DLL +L + P +R + LAHP+
Sbjct: 260 ARNYLLSLPHKNKVP---WNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL--- 313
Query: 323 RNERYFFPS 331
E+Y+ PS
Sbjct: 314 --EQYYDPS 320
>CE19302_1 [G] KOG0658 Glycogen synthase kinase-3
Length = 396
Score = 141 bits (355), Expect = 2e-33
Identities = 95/297 (31%), Positives = 149/297 (49%), Gaps = 25/297 (8%)
Query: 35 QGAFGTVVQA-YLTPDNQKWLGPFAIKKVPAQTEYKSRELEIL---RIADHPNVVKLEYF 90
+G F V + L+P ++ + AIKK +T Y++ EL L R H N+V++ +
Sbjct: 35 RGVFSNVYRGTILSPGTEQEI---AIKKTWPKTPYRNFELLFLSGLRRKPHKNIVQMLFA 91
Query: 91 YTHISPTD------HKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
++ + + H + +P LQN + + + +++ KLY +Q+ G+
Sbjct: 92 FSRNTTSGEGLEMKHSFCESYVFGFMPYTLQNILKKTRLAEVDM-----KLYTWQLFEGI 146
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
YL A I HRDIKP N+LVD G LKI DFGSAK + S SY +R+YR PEL++
Sbjct: 147 RYLQAHMIVHRDIKPVNILVDVDKGTLKIADFGSAKVVLRGSSSTSYQVTRFYRPPELLL 206
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
+Y +D+W GC +GEM+ GK +F G + L I + +G P R + + S
Sbjct: 207 DAKEYYWMVDVWSAGCCVGEMMKGKVLFPGASIKIMLKLIVQAIGLPSARDLDYMKVS-- 264
Query: 265 GPLFSKPLFEGAPKA-RFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
S + A K ++ G + D L ++L Y P R ++L+HPFFD
Sbjct: 265 ----SMIDQQSAVKVIGLKEVLGTENQEWADFLGAILRYRPRERLHGPKLLSHPFFD 317
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 140 bits (353), Expect = 3e-33
Identities = 99/309 (32%), Positives = 157/309 (50%), Gaps = 29/309 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QT--EYKSRELEILRIADHPNVVKL 87
IG+GA+G V AY + + AIKK+ QT + RE++IL H N++ +
Sbjct: 31 IGEGAYGMVCSAYDNVNKVR----VAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGI 86
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+PT + Q + + ++++ ++ + K L H+ + YQI RG+ Y+
Sbjct: 87 NDIIR--APT---IEQMKDVYIVQDLMETDLYKLLKTQ-HLSNDHICYFLYQILRGLKYI 140
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS----YICSRYYRAPELI 203
H+ + HRD+KPSN+L++ T LKICDFG A+ + + Y+ +R+YRAPE++
Sbjct: 141 HSANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIM 199
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPS 262
+ YT IDIW +GC+L EML + +F G L QL I +LG P + + N
Sbjct: 200 LNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNCIINLK 259
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
L S P P + + F A +DLL +L + P +R + LAHP+
Sbjct: 260 ARNYLLSLPHKNKVP---WNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL--- 313
Query: 323 RNERYFFPS 331
E+Y+ PS
Sbjct: 314 --EQYYDPS 320
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 140 bits (353), Expect = 3e-33
Identities = 92/310 (29%), Positives = 158/310 (50%), Gaps = 31/310 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILR-IADHPN 83
KR+G+GA+G V +AY +++ A+KK+ P ++ RE+ L+ HPN
Sbjct: 17 KRLGKGAYGIVWKAY----DKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPN 72
Query: 84 VVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
V+KL + + D +Y LA E + L N I KK ++ L H + Q+ R
Sbjct: 73 VIKLYNIFR--ADNDRDIY--LAFEFMEADLHNVI---KKGSI-LKDVHKQYIMCQLFRA 124
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES--------NQPSIS-YICS 194
+ +LH+ + HRD+KPSNVL+D + K+ DFG A+ L S P ++ Y+ +
Sbjct: 125 IRFLHSGNVLHRDLKPSNVLLDADCRV-KLADFGLARSLSSLEDYPEGQKMPDLTEYVAT 183
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
R+YR+PE+++ +YT +D+W LGC+L EML+G+A+F G + Q+ I + P +
Sbjct: 184 RWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRA 243
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
I Y + K P+ + + +D++ +L++ P++R + + L
Sbjct: 244 DIASIGSHYAASVLEK--MPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKRLTVEQCL 301
Query: 315 AHPFFDDLRN 324
HP+ N
Sbjct: 302 VHPYVVQFHN 311
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 140 bits (352), Expect = 4e-33
Identities = 101/296 (34%), Positives = 149/296 (50%), Gaps = 24/296 (8%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNVV 85
+IGQG + V +A + A+KKV P + +RE+ ILR DHPNV+
Sbjct: 146 KIGQGTYSIVYKARDLETGKI----VAMKKVRFANMDPESVRFMAREINILRKLDHPNVM 201
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
KL+ T S L HL E + L LR ++ +K + Q+ G+
Sbjct: 202 KLQCLVT--SKLSGSL--HLVFEYMEHDLSGLALR---PGVKFTEPQIKCFMKQLLCGLE 254
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYICSRYYRAPELI 203
+ H+ GI HRDIK SN+LV+ G+LKI DFG A K + +QP S + + +YRAPEL+
Sbjct: 255 HCHSRGILHRDIKGSNLLVN-NDGVLKIGDFGLASFYKPDQDQPLTSRVVTLWYRAPELL 313
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSY 263
+G T+Y ID+W +GC+L E+ + K + G + Q+H+I KL G P + F++ +
Sbjct: 314 LGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEE--FWNTTKF 371
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
KP + K + F +DLL +L EPE+R S L FF
Sbjct: 372 PQATSYKP--QHPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFF 425
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 140 bits (352), Expect = 4e-33
Identities = 98/307 (31%), Positives = 149/307 (47%), Gaps = 33/307 (10%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADH 81
++ R+G+G++G V Y D + A+K+ PA + RE+ +L+ H
Sbjct: 5 EKLSRLGEGSYGVV---YKCRDRETG-ALVAVKRFVESEDDPAIRKIALREIRLLKNLKH 60
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
PN+V L + K HL E + +E+ R+ + P K YQ
Sbjct: 61 PNLVSLLEVFRR------KRRLHLVFEFCELTVLHELERHPQG---CPEHLTKQICYQTL 111
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPE 201
G+ Y H G HRDIKP N+L+ Q G +K+CDFG A+ L + Y+ +R+YRAPE
Sbjct: 112 LGVAYCHKQGCLHRDIKPENILLTAQ-GQVKLCDFGFARMLSPGENYTDYVATRWYRAPE 170
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP--PDKRFIFFS 259
L+VG TQY T +D+W +GC+ E++ G+A++ G + QL+ I K LG P IF
Sbjct: 171 LLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQ 230
Query: 260 NPSYNG-----PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
N + G P +PL + P P +D L L +P +R S ++
Sbjct: 231 NEYFKGITLPVPPTLEPLEDKMPAK------SQQNPLTIDFLKKCLDKDPTKRWSCEKLT 284
Query: 315 AHPFFDD 321
H +FDD
Sbjct: 285 KHSYFDD 291
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 139 bits (351), Expect = 5e-33
Identities = 102/340 (30%), Positives = 166/340 (48%), Gaps = 23/340 (6%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKSR----ELEILRIADHPNVVK 86
+G GA+G+V AY QK A+KK+ P Q+ +R EL +L+ H NV+
Sbjct: 30 VGSGAYGSVCSAYDARLRQK----VAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L +T + + +L + L N + ++ +HV+ YQ+ RG+ Y
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSD-----EHVQFLVYQLLRGLKY 140
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ GI HRD+KPSNV V+ L+I DFG A+ ++++ Y+ +R+YRAPE+++
Sbjct: 141 IHSAGIIHRDLKPSNVAVNEDCE-LRILDFGLAR--QADEEMTGYVATRWYRAPEIMLNW 197
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGP 266
Y +DIW +GC++ E+L GKA+F G + QL I +++G P + S +
Sbjct: 198 MHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPE-VLAKISSEHAR 256
Query: 267 LFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD---DLR 323
+ + L P+ F A P +DLL +LV + ++R S LAH +F D
Sbjct: 257 TYIQSL-PPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPE 315
Query: 324 NERYFFPSGSSQPKHLPPLYDFSDFELQVIGDLFPKIQPK 363
+E P S L ++ + Q + P PK
Sbjct: 316 DEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPK 355
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 139 bits (351), Expect = 5e-33
Identities = 95/310 (30%), Positives = 157/310 (50%), Gaps = 31/310 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+G+G++G V A G AIKK+ E+ S RE+++LR+ HP++V+
Sbjct: 22 VGKGSYGVVASAECPHTG----GKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHPDIVE 77
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+++ + P K ++ + + + E++++++ K N +L +H + + YQ+ RG+ +
Sbjct: 78 IKHI---MLPPCRKEFKDIYV--VFELMESDLHHVLKVNDDLTPQHHQFFLYQLLRGLKF 132
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI----SYICSRYYRAPEL 202
+H+ + HRD+KP N+L + I KICD G A+ ++ PS Y+ +R+YRAPEL
Sbjct: 133 MHSAHVFHRDLKPKNILANADCKI-KICDLGLARVSFTDSPSAVFWTDYVATRWYRAPEL 191
Query: 203 IVGC-TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD----KRFIF 257
+ YT ID+W +GC+ EML GK +F G + QL +T LLG P R
Sbjct: 192 CGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITLSRIRN 251
Query: 258 FSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
Y G + K F F P + LL ++ ++P+ R S LA P
Sbjct: 252 EKARKYLGNMRRK------DPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADP 305
Query: 318 FFDDLRNERY 327
+F L N Y
Sbjct: 306 YFQGLANVDY 315
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 139 bits (350), Expect = 7e-33
Identities = 103/314 (32%), Positives = 156/314 (48%), Gaps = 34/314 (10%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEI 75
KR L+KE IG GA+G V A + AIKKV + REL++
Sbjct: 21 KRFQLIKE---IGHGAYGIVCSARFAEAAEDTT--VAIKKVTNVFSKTLLCKRSLRELKL 75
Query: 76 LR-IADHPNVVKLE----YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPL 130
LR H N+ L FY S LY+ L MEC ++ + K+ L
Sbjct: 76 LRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEEL-MEC-------DMHQIIKSGQPLTD 127
Query: 131 KHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK-----KLESN 185
H + + YQI G+ Y+H+ + HRD+KP N+LV+ LKICDFG A+ +E++
Sbjct: 128 AHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-LKICDFGLARGYSENPVENS 186
Query: 186 QPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEIT 245
Q Y+ +R+YRAPE+++ YT ID+W GC+L E L GK +F+G + QL++I
Sbjct: 187 QFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQIL 246
Query: 246 KLLG-PPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEP 304
++LG PPD+ + + + PK F + A +DLL +L ++P
Sbjct: 247 QVLGTPPDETLRRIGSKNVQDYIHQLGFI---PKVPFVNLYPNANSQALDLLEQMLAFDP 303
Query: 305 ERRASPRRILAHPF 318
++R + L HP+
Sbjct: 304 QKRITVDEALEHPY 317
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 139 bits (350), Expect = 7e-33
Identities = 98/323 (30%), Positives = 158/323 (48%), Gaps = 40/323 (12%)
Query: 25 MLVKEYKR---IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEI 75
+++K Y+ IG GA G V A+ T N++ AIKK+ + REL++
Sbjct: 114 VVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQ----VAIKKLSRPFQNVTHAKRAYRELKL 169
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKL 135
+ + +H N++ + +T D ++ ME + L I ++L + +
Sbjct: 170 MSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVI------QMDLDHERLSY 223
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSR 195
YQ+ G+ +LH+ GI HRD+KPSN++V LKI DFG A+ Y+ +R
Sbjct: 224 LLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDC-TLKILDFGLARTAIEAFMMTPYVVTR 282
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
YYRAPE+I+G Y +D+W +GC+ GE++ G+ +F G + Q I + LG PD+ F
Sbjct: 283 YYRAPEVILGMG-YKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSF 341
Query: 256 IFFSNPSYNGPLFSKPLFEGAPKARFEKYFG------------YAGPDGVDLLMSVLVYE 303
+ P+ + ++P ++ P FE F G DLL +LV +
Sbjct: 342 LERLQPTVRNYVENRPRYQATP---FEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVID 398
Query: 304 PERRASPRRILAHPF----FDDL 322
PERR S L HP+ FD++
Sbjct: 399 PERRISVDDALRHPYVNVWFDEI 421
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 139 bits (349), Expect = 9e-33
Identities = 106/340 (31%), Positives = 168/340 (49%), Gaps = 50/340 (14%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLG-PFAIKKVPA----QTEYKS--RELEILRIAD 80
++ K IG GA G V A+ T LG A+KK+ QT K REL +L+ +
Sbjct: 27 QQLKPIGSGAQGIVCAAFDTV-----LGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N++ L +T + +L ME + L I ++EL + + YQ+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------HMELDHERMSYLLYQM 135
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAP 200
G+ +LH+ GI HRD+KPSN++V LKI DFG A+ +N Y+ +RYYRAP
Sbjct: 136 LCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVVTRYYRAP 194
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+I+G Y +DIW +GC++GE++ G +FQG + Q +++ + LG P F+
Sbjct: 195 EVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQ 253
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV----------------DLLMSVLVYEP 304
P+ + ++P + P +FE+ F PD + DLL +LV +P
Sbjct: 254 PTVRNYVENRPKY---PGIKFEELF----PDWIFPSESERDKIKTSQARDLLSKMLVIDP 306
Query: 305 ERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYD 344
++R S L HP+ ++ P+ + P P +YD
Sbjct: 307 DKRISVDEALRHPYI-----TVWYDPAEAEAPP--PQIYD 339
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 139 bits (349), Expect = 9e-33
Identities = 106/340 (31%), Positives = 168/340 (49%), Gaps = 50/340 (14%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLG-PFAIKKVPA----QTEYKS--RELEILRIAD 80
++ K IG GA G V A+ T LG A+KK+ QT K REL +L+ +
Sbjct: 27 QQLKPIGSGAQGIVCAAFDTV-----LGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N++ L +T + +L ME + L I ++EL + + YQ+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------HMELDHERMSYLLYQM 135
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAP 200
G+ +LH+ GI HRD+KPSN++V LKI DFG A+ +N Y+ +RYYRAP
Sbjct: 136 LCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVVTRYYRAP 194
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+I+G Y +DIW +GC++GE++ G +FQG + Q +++ + LG P F+
Sbjct: 195 EVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQ 253
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV----------------DLLMSVLVYEP 304
P+ + ++P + P +FE+ F PD + DLL +LV +P
Sbjct: 254 PTVRNYVENRPKY---PGIKFEELF----PDWIFPSESERDKIKTSQARDLLSKMLVIDP 306
Query: 305 ERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYD 344
++R S L HP+ ++ P+ + P P +YD
Sbjct: 307 DKRISVDEALRHPYI-----TVWYDPAEAEAPP--PQIYD 339
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 139 bits (349), Expect = 9e-33
Identities = 106/340 (31%), Positives = 168/340 (49%), Gaps = 50/340 (14%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLG-PFAIKKVPA----QTEYKS--RELEILRIAD 80
++ K IG GA G V A+ T LG A+KK+ QT K REL +L+ +
Sbjct: 27 QQLKPIGSGAQGIVCAAFDTV-----LGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N++ L +T + +L ME + L I ++EL + + YQ+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------HMELDHERMSYLLYQM 135
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAP 200
G+ +LH+ GI HRD+KPSN++V LKI DFG A+ +N Y+ +RYYRAP
Sbjct: 136 LCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVVTRYYRAP 194
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+I+G Y +DIW +GC++GE++ G +FQG + Q +++ + LG P F+
Sbjct: 195 EVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQ 253
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV----------------DLLMSVLVYEP 304
P+ + ++P + P +FE+ F PD + DLL +LV +P
Sbjct: 254 PTVRNYVENRPKY---PGIKFEELF----PDWIFPSESERDKIKTSQARDLLSKMLVIDP 306
Query: 305 ERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYD 344
++R S L HP+ ++ P+ + P P +YD
Sbjct: 307 DKRISVDEALRHPYI-----TVWYDPAEAEAPP--PQIYD 339
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 139 bits (349), Expect = 9e-33
Identities = 98/315 (31%), Positives = 157/315 (49%), Gaps = 33/315 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP----AQTEYKS--RELEILRIADHPNV 84
+ +G GA+G V +A T + ++ AIKK+P A T K RE+ ILR H N+
Sbjct: 61 ENVGAGAYGVVCKAMDTRNKKQ----VAIKKIPRAFTAHTLAKRSLREVRILRELLHENI 116
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ + +T +Y L M+ + L ++IL ++ +E +H + + YQ+ RG+
Sbjct: 117 IAVLDMFTAEGAHGKDIY--LVMDLMETDL-HQILHSRQTLME---QHFQYFFYQLLRGL 170
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQP----------SISYICS 194
YLH+ GI HRD+KPSN+L++ +L+I DFG A+ S Y+ +
Sbjct: 171 KYLHSAGIIHRDLKPSNLLLNGDC-LLRIADFGMARAYASASTVRDDANVGGHMTQYVST 229
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
R+YRAPE++ +Y TK+D+W GC+ EMLL + +F G + Q+ I LG P++
Sbjct: 230 RWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEE 289
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKA--RFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
I L + K F F A P+ +++ +L P +R S +
Sbjct: 290 VI----NRITSDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQ 345
Query: 313 ILAHPFFDDLRNERY 327
IL HPF N++Y
Sbjct: 346 ILQHPFMAQYHNDQY 360
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 139 bits (349), Expect = 9e-33
Identities = 96/298 (32%), Positives = 153/298 (51%), Gaps = 28/298 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKV------PAQTEYKSRELEILRIADHPNV 84
+IGQG + V +A G A+KKV P ++ +RE+ +LR DHPNV
Sbjct: 123 KIGQGTYSNVYKA-----KDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNV 177
Query: 85 VKLEYFYT-HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
VKLE T +S + + ++Q++ + L + + ++++ ++ VK Q+ G
Sbjct: 178 VKLEGLVTSRMSCSLYLVFQYMDHD-LAGLASSPVVKFSESE-------VKCLMRQLISG 229
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN--QPSISYICSRYYRAPE 201
+ + H+ G+ HRDIK SN+L+D G+LKI DFG A + N +P S + + +YRAPE
Sbjct: 230 LEHCHSRGVLHRDIKGSNLLID-DGGVLKIADFGLATIFDPNHKRPMTSRVVTLWYRAPE 288
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNP 261
L++G T Y ID+W GC+L E+L G+ + G + QLH+I KL G P + ++
Sbjct: 289 LLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSED--YWKKG 346
Query: 262 SYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ KP K + F P + L+ ++L EPE R + L FF
Sbjct: 347 KFTHGAIYKP--REPYKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSEFF 402
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 138 bits (347), Expect = 1e-32
Identities = 98/306 (32%), Positives = 155/306 (50%), Gaps = 34/306 (11%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--------PAQTEYKSRELEILR-IADH 81
KR+G+GA+G V +A +++ A+KKV AQ Y RE+ LR H
Sbjct: 29 KRMGKGAYGIVWKA----TDRRTKNTVALKKVFDAFRDETDAQRTY--REVIFLRAFRCH 82
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
PN+V+L I + L +L E + L N I K+ N+ L H + YQ+
Sbjct: 83 PNIVRL----VDIFKASNNLDFYLVFEFMESDLHNVI---KRGNV-LKDVHKRFVMYQLI 134
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQ---------PSISYI 192
+ ++H+ + HRD+KPSN+L+D + LK+ DFG A+ L S + Y+
Sbjct: 135 NAIKFIHSGNVIHRDLKPSNILIDSKCR-LKVADFGLARTLSSRRIYDDLEQDGMLTDYV 193
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+R+YRAPE++V YT ID+WGLGC+LGEM+ K +FQG + Q+ +I L
Sbjct: 194 ATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVT 253
Query: 253 KRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
K I PS+ L S+ + + + ++ DG+ L+ ++LV P R + +
Sbjct: 254 KLDIASIGPSFGSVLLSRNI-QRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKE 312
Query: 313 ILAHPF 318
+ HP+
Sbjct: 313 AIRHPY 318
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 137 bits (345), Expect = 2e-32
Identities = 106/336 (31%), Positives = 162/336 (47%), Gaps = 42/336 (12%)
Query: 28 KEYKRIGQGAFGTVVQA-YLTPDNQKWLGPFAIKKVPAQTEYK------SRELEILRIAD 80
+E +++GQG FG V + +L Q A+KK+ E RE+ IL+ +
Sbjct: 61 REDEKLGQGTFGEVYKGIHLETQRQ-----VAMKKIIVSVEKDLFPITAQREITILKRLN 115
Query: 81 HPNVVKL-EYFYTH----ISPTDHKLYQHLAMECLPEMLQN--EILRYKKNNLELPLKHV 133
H N++KL E Y H + L++ M LP M+ + +L + NLE+ +
Sbjct: 116 HKNIIKLIEMVYDHSPDITNAASSNLHKSFYM-ILPYMVADLSGVLHNPRINLEMC--DI 172
Query: 134 KLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-- 191
K QI G+ Y+H HRDIK +N+L+D G+LK+ DFG A+ P++ Y
Sbjct: 173 KNMMLQILEGLNYIHCAKFMHRDIKTANILID-HNGVLKLADFGLARLYYGCPPNLKYPG 231
Query: 192 -----------ICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQ 240
+ +R+YRAPEL++G QYTT +DIWG+GCV E K + QG + Q
Sbjct: 232 GAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQ 291
Query: 241 LHEITKLLGPPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVL 300
H I KLLG P + + G + ++ + RF KY G+D L +L
Sbjct: 292 GHVIFKLLGTPTEEDWAVAR-YLPGAELTTTNYKPTLRERFGKYL---SETGLDFLGQLL 347
Query: 301 VYEPERRASPRRILAHPFF--DDLRNERYFFPSGSS 334
+P +R + HP+F D L +E+ P+ S
Sbjct: 348 ALDPYKRLTAMSAKHHPWFKEDPLPSEKITLPTEES 383
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 137 bits (345), Expect = 2e-32
Identities = 106/340 (31%), Positives = 167/340 (48%), Gaps = 50/340 (14%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLG-PFAIKKVPA----QTEYKS--RELEILRIAD 80
++ K IG GA G V A+ T LG A+KK+ QT K REL +L+ +
Sbjct: 27 QQLKPIGSGAQGIVCAAFDTV-----LGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N++ L +T + +L ME + L I ++EL + + YQ+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------HMELDHERMSYLLYQM 135
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAP 200
G+ +LH+ GI HRD+KPSN++V LKI DFG A+ +N Y+ +RYYRAP
Sbjct: 136 LCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVVTRYYRAP 194
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+I+G Y +DIW +GC++ EM+L K +F G + Q +++ + LG P F+
Sbjct: 195 EVILGMG-YKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQ 253
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV----------------DLLMSVLVYEP 304
P+ + ++P + P +FE+ F PD + DLL +LV +P
Sbjct: 254 PTVRNYVENRPKY---PGIKFEELF----PDWIFPSESERDKIKTSQARDLLSKMLVIDP 306
Query: 305 ERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYD 344
++R S L HP+ ++ P+ + P P +YD
Sbjct: 307 DKRISVDEALRHPYI-----TVWYDPAEAEAPP--PQIYD 339
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 137 bits (345), Expect = 2e-32
Identities = 106/340 (31%), Positives = 167/340 (48%), Gaps = 50/340 (14%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLG-PFAIKKVPA----QTEYKS--RELEILRIAD 80
++ K IG GA G V A+ T LG A+KK+ QT K REL +L+ +
Sbjct: 27 QQLKPIGSGAQGIVCAAFDTV-----LGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N++ L +T + +L ME + L I ++EL + + YQ+
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------HMELDHERMSYLLYQM 135
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAP 200
G+ +LH+ GI HRD+KPSN++V LKI DFG A+ +N Y+ +RYYRAP
Sbjct: 136 LCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTACTNFMMTPYVVTRYYRAP 194
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+I+G Y +DIW +GC++ EM+L K +F G + Q +++ + LG P F+
Sbjct: 195 EVILGMG-YKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQ 253
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV----------------DLLMSVLVYEP 304
P+ + ++P + P +FE+ F PD + DLL +LV +P
Sbjct: 254 PTVRNYVENRPKY---PGIKFEELF----PDWIFPSESERDKIKTSQARDLLSKMLVIDP 306
Query: 305 ERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYD 344
++R S L HP+ ++ P+ + P P +YD
Sbjct: 307 DKRISVDEALRHPYI-----TVWYDPAEAEAPP--PQIYD 339
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 137 bits (345), Expect = 2e-32
Identities = 100/311 (32%), Positives = 154/311 (49%), Gaps = 33/311 (10%)
Query: 33 IGQGAFGTVVQAY----LTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLE 88
IG+GA+G V AY T K + PF + +T RE++IL H NV+ +
Sbjct: 48 IGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRT---LREIQILLRFRHENVIGIR 104
Query: 89 YFY---THISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
T + D + Q L L ++L+++ +L H+ + YQI RG+
Sbjct: 105 DILRASTLEAMRDVYIVQDLMETDLYKLLKSQ---------QLSNDHICYFLYQILRGLK 155
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS----YICSRYYRAPE 201
Y+H+ + HRD+KPSN+L++ T LKICDFG A+ + Y+ +R+YRAPE
Sbjct: 156 YIHSANVLHRDLKPSNLLINT-TCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSN 260
+++ YT IDIW +GC+L EML + +F G L QL+ I +LG P + + N
Sbjct: 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
L S P K + K F + +DLL +L + P +R + LAHP+
Sbjct: 275 MKARNYLQSLP---SKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYL- 330
Query: 321 DLRNERYFFPS 331
E+Y+ P+
Sbjct: 331 ----EQYYDPT 337
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 137 bits (344), Expect = 3e-32
Identities = 88/300 (29%), Positives = 150/300 (49%), Gaps = 28/300 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA-----QTEYKSRELEILRIADHPNVVK 86
++G G +GTVV +K AIK++ + RE++ L+ HPN+VK
Sbjct: 9 QLGDGTYGTVVLGQRKDTGEK----VAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVK 64
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L+ + + LY E + E L I K + LP +K +Q+ G+ +
Sbjct: 65 LK----EVIRENDTLY--FVFEYMKENLYQMI---KDRDTHLPEPELKSILFQVLTGLAF 115
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H G HRD+KP N+L ++KI DFG A+++ S P Y+ +R+YRAPE+++
Sbjct: 116 MHRHGFFHRDLKPENLLCSGPD-LIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHS 174
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGP 266
T Y + ID+W +GC++ E+ + +F G + QL +I +LG PDK + +G
Sbjct: 175 TNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDK------DDWPDGY 228
Query: 267 LFSKPLFEGAP---KARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLR 323
+ + P K +G+DLL +L Y+P++R + ++ L +P+F L+
Sbjct: 229 RLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYFHALK 288
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 136 bits (342), Expect = 6e-32
Identities = 96/301 (31%), Positives = 156/301 (50%), Gaps = 28/301 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+G+GA+G V++ ++ AIKK E + REL++LR N+V+
Sbjct: 19 VGEGAYGVVLKCRHKETHEI----VAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVE 74
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L+ + KLY L E + + + E+L N + P + VK Y YQ+ + + +
Sbjct: 75 LKEAFRRRG----KLY--LVFEYVEKNML-ELLEEMPNGV--PPEKVKSYIYQLIKAIHW 125
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLE--SNQPSISYICSRYYRAPELIV 204
H I HRDIKP N+L+ +LK+CDFG A+ L +N Y+ +R+YR+PEL++
Sbjct: 126 CHKNDIVHRDIKPENLLIS-HNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL 184
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG--PPDKRFIFFSNPS 262
G Y +D+W +GC+LGE+ G+ +F G + QL I K+LG P ++ +F+SNP
Sbjct: 185 GAP-YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPR 243
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
++G F P++ +Y G +DL+ ++L +P R + L HP F
Sbjct: 244 FHGLRFPA---VNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
Query: 323 R 323
R
Sbjct: 301 R 301
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 135 bits (341), Expect = 7e-32
Identities = 103/326 (31%), Positives = 160/326 (48%), Gaps = 32/326 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKW----LGPFAIKKVPAQTEYKSRELEILR-IADHPNVVKL 87
IG+GA+GTV A P K + PF+ K +T RE+++LR +H N++ +
Sbjct: 19 IGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRT---IREIKLLRYFHEHENIISI 75
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+S D +L E + LQ I L HV+ + YQI R + +
Sbjct: 76 LDKVRPVS-IDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSI 134
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS--------ISYICSRYYRA 199
H+ + HRDIKPSN+L++ LK+CDFG A+ L S+ S Y+ +R+YRA
Sbjct: 135 HSAQVIHRDIKPSNLLLNSNCD-LKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRA 193
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD-KRFIFF 258
PE+++ +YTT +DIW GC+L EM+ GK +F G QL I ++LG P + F
Sbjct: 194 PEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQI 253
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYA--GPDGVDLLMSVLVYEPERRASPRRILAH 316
+ + + P+ P +E + PD +DLL +L + P++R S L H
Sbjct: 254 KSKRAKEYIANLPM---RPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRH 310
Query: 317 PFFDDLRNERYFFPSGSSQPKHLPPL 342
P+ + S +P++ PPL
Sbjct: 311 PYL-------AMYHDPSDEPEY-PPL 328
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 135 bits (341), Expect = 7e-32
Identities = 96/294 (32%), Positives = 150/294 (50%), Gaps = 22/294 (7%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADHPNVVK 86
+G GA+G+V A+ T + A+KK+ P Q+ + REL +L+ H NV+
Sbjct: 30 VGSGAYGSVCAAFDTKTGLR----VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIG 85
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L +T + +L + L N I++ +K L HV+ YQI RG+ Y
Sbjct: 86 LLDVFTPARSLEEFNDVYLVTHLMGADLNN-IVKCQK----LTDDHVQFLIYQILRGLKY 140
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ I HRD+KPSN+ V+ LKI DFG A+ + Y+ +R+YRAPE+++
Sbjct: 141 IHSADIIHRDLKPSNLAVNEDCE-LKILDFGLARHTDDEMTG--YVATRWYRAPEIMLNW 197
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPSYNG 265
Y +DIW +GC++ E+L G+ +F G + QL I +L+G P + S+ S
Sbjct: 198 MHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARN 257
Query: 266 PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ S PK F F A P VDLL +LV + ++R + + LAH +F
Sbjct: 258 YIQS---LTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYF 308
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 135 bits (341), Expect = 7e-32
Identities = 100/326 (30%), Positives = 159/326 (48%), Gaps = 32/326 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG GA+G V A Q+ AIKK+P + REL+IL+ H N++
Sbjct: 61 IGNGAYGVVSSARRRLTGQQ----VAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIA 116
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
++ P ++ ++ ++++++ + ++ L L+HV+ + YQ+ RG+ Y
Sbjct: 117 IKDILRPTVPYGEFKSVYVVLD----LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL-----ESNQPSISYICSRYYRAPE 201
+H+ + HRD+KPSN+LV+ LKI DFG A+ L E Y+ +R+YRAPE
Sbjct: 173 MHSAQVIHRDLKPSNLLVNENCE-LKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPE 231
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSN 260
L++ +YT ID+W +GC+ GEML + +F G + QL I +LG P I
Sbjct: 232 LMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGA 291
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
+ S P + P +E + A + LL +L +EP R S L HPF
Sbjct: 292 ERVRAYIQSLPPRQPVP---WETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL- 347
Query: 321 DLRNERYFFPSGSSQPKHLPPLYDFS 346
+Y P +P PP +DF+
Sbjct: 348 ----AKYHDP--DDEPDCAPP-FDFA 366
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 135 bits (341), Expect = 7e-32
Identities = 100/326 (30%), Positives = 159/326 (48%), Gaps = 32/326 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG GA+G V A Q+ AIKK+P + REL+IL+ H N++
Sbjct: 61 IGNGAYGVVSSARRRLTGQQ----VAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIA 116
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
++ P ++ ++ ++++++ + ++ L L+HV+ + YQ+ RG+ Y
Sbjct: 117 IKDILRPTVPYGEFKSVYVVLD----LMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKY 172
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL-----ESNQPSISYICSRYYRAPE 201
+H+ + HRD+KPSN+LV+ LKI DFG A+ L E Y+ +R+YRAPE
Sbjct: 173 MHSAQVIHRDLKPSNLLVNENCE-LKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPE 231
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSN 260
L++ +YT ID+W +GC+ GEML + +F G + QL I +LG P I
Sbjct: 232 LMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGA 291
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
+ S P + P +E + A + LL +L +EP R S L HPF
Sbjct: 292 ERVRAYIQSLPPRQPVP---WETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL- 347
Query: 321 DLRNERYFFPSGSSQPKHLPPLYDFS 346
+Y P +P PP +DF+
Sbjct: 348 ----AKYHDP--DDEPDCAPP-FDFA 366
>CE09532 [G] KOG0658 Glycogen synthase kinase-3
Length = 440
Score = 135 bits (340), Expect = 9e-32
Identities = 90/308 (29%), Positives = 149/308 (48%), Gaps = 22/308 (7%)
Query: 20 NVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRI- 78
N K + ++E G F V + L +K + AIKK + E R E + +
Sbjct: 16 NKKVMLKIEEVHLHSCGVFSNVYKGILREPYEKKI---AIKK--SWPEKGERNFEFIFLT 70
Query: 79 ----ADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVK 134
A H NV+ + + ++H D K+ + + +P L E++R K +L+ ++
Sbjct: 71 GRERAKHKNVIHMIFAFSH--SYDTKVCESYVFDFMPNTLA-EVIRQKLTDLD-----IR 122
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICS 194
LY +QI G+ YL + HRD+KP N+LVD T LKI DFGSAK + + + Y +
Sbjct: 123 LYTWQIFSGLKYLEEHKVVHRDLKPVNILVDHDTAFLKISDFGSAKIIVKGKANNFYQVT 182
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
R+YR PEL++ +Y + +D+W GC++ EM+ VF G QL + G P+++
Sbjct: 183 RFYRPPELLMKAMEYNSTVDVWSAGCIMAEMVKRHVVFPGRDSAHQLKLYCRCFGAPNEQ 242
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
I + G K ++ ++ PD + + +LVY PE+R +++L
Sbjct: 243 DI----SAMKGEKLEKEYWKFTKGFGLQRLVNDISPDQLQFIKRILVYAPEKRLRGKQLL 298
Query: 315 AHPFFDDL 322
FF L
Sbjct: 299 QDDFFRPL 306
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 135 bits (340), Expect = 9e-32
Identities = 100/306 (32%), Positives = 149/306 (48%), Gaps = 24/306 (7%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEI 75
+R ++ +IGQG + +V +A + A+KKV P + +RE+ I
Sbjct: 151 RRAESFEKLDKIGQGTYSSVYRARDLETGKM----VAMKKVRFVNMDPESVRFMAREINI 206
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKL 135
LR DHPNV+KLE T S LY L E + L LR ++ +K
Sbjct: 207 LRKLDHPNVMKLECLVT--SKLSGSLY--LVFEYMEHDLSGLALR---PGVKFTESQIKC 259
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL--ESNQPSISYIC 193
Y Q+ G+ + H+ GI HRDIK N+LV+ G+LKI DFG A E +QP S +
Sbjct: 260 YMKQLLSGLEHCHSRGILHRDIKGPNLLVN-NDGVLKIGDFGLANIYHPEQDQPLTSRVV 318
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDK 253
+ +YRAPEL++G T+Y ID+W +GC+L E+ LGK + G + Q+H+I K G P
Sbjct: 319 TLWYRAPELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSD 378
Query: 254 RFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRI 313
+ PL + + K + F P + L+ +L EP +R +
Sbjct: 379 DYW----QKTKLPLATSFKPQQPYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASST 434
Query: 314 LAHPFF 319
L+ FF
Sbjct: 435 LSSKFF 440
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 135 bits (340), Expect = 9e-32
Identities = 80/233 (34%), Positives = 133/233 (56%), Gaps = 22/233 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNVV 85
+IGQG + V +A D +K + A+KKV P + +RE++ILR DHPN++
Sbjct: 139 KIGQGTYSNVYRAR-DLDQKKIV---ALKKVRFDNLEPESVRFMAREIQILRRLDHPNII 194
Query: 86 KLEYFYT-HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
KLE T +S + + +++++ + L + + +++ ++ VK Y Q+ G+
Sbjct: 195 KLEGLVTSRMSCSLYLVFEYMEHD-LAGLASHPAIKFSESQ-------VKCYLQQLLHGL 246
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLE--SNQPSISYICSRYYRAPEL 202
+ H+ G+ HRDIK SN+L+D +G+LKI DFG A + QP S + + +YR PEL
Sbjct: 247 DHCHSRGVLHRDIKGSNLLID-NSGVLKIADFGLASFFDPRQTQPLTSRVVTLWYRPPEL 305
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
++G T+Y +D+W GC+L E+ GK + G + QLH+I KL G P + +
Sbjct: 306 LLGATRYGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDY 358
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 135 bits (339), Expect = 1e-31
Identities = 96/306 (31%), Positives = 150/306 (48%), Gaps = 29/306 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEIL-RIAD 80
K K +GQGA+G V A + AIKK+ T+ RE+++L +
Sbjct: 22 KVVKELGQGAYGIVCAARNVASKDQ--EAVAIKKITNVFSKSILTKRALREIKLLIHFRN 79
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N+ + Y I+P Y + E+++ ++ K+ L H + + YQI
Sbjct: 80 HRNITCI-YDLDIINP-----YNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQI 133
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS-----ISYICSR 195
G+ Y+H+ + HRD+KP N+LV+ LKICDFG A+ N Y+ +R
Sbjct: 134 LCGLKYIHSANVIHRDLKPGNLLVNADCE-LKICDFGLARGCSENPEENPGFMTEYVATR 192
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
+YRAPE+++ + Y ID+W +GC+L E+L G +F+G + QL+ I LG PD+
Sbjct: 193 WYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEET 252
Query: 256 IFFSNPSYNGPLFSKPLFEGAPKAR---FEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
+ S+ ++ PK R FE F A P +DLL +L ++P RR S
Sbjct: 253 L-----SHISSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDD 307
Query: 313 ILAHPF 318
L HP+
Sbjct: 308 ALEHPY 313
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 134 bits (337), Expect = 2e-31
Identities = 92/308 (29%), Positives = 153/308 (48%), Gaps = 34/308 (11%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
+ +G GAFG V +A + N++ AIKK+ + +S RE+ I R H N+
Sbjct: 48 ENLGAGAFGVVCRAIDSKLNKQ----VAIKKITRVFKNQSTAKCALREIRITRELSHENI 103
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ S + +Y + ++++ ++L K+N L KH + + YQI +G+
Sbjct: 104 INSTDVLMRESGSGQDIY------IVMDLMETDLLSVLKSNQTLNEKHFQYFFYQILKGL 157
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFG------SAKKLESNQPSI-------SY 191
YLH+ GI HRD+KP+N+L++ LKI DFG S K + P+ Y
Sbjct: 158 KYLHSAGIIHRDLKPANLLLNEDCS-LKIADFGMSRSGPSTKTTPNTSPNAHISGDLSQY 216
Query: 192 ICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP 251
+ + +YRAPE+++ +Y T++DIW GC+L EMLL + +F G Q+ + + LG P
Sbjct: 217 VSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLLIEYLGTP 276
Query: 252 DKRFI-FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASP 310
D++ I +PS + S F F F A + +++ +L P +R S
Sbjct: 277 DEQVIRRIKSPSIRDYISS---FGPKTPLPFTAMFPNASIEARNIVSKMLQISPWKRFSA 333
Query: 311 RRILAHPF 318
++L PF
Sbjct: 334 EQLLEEPF 341
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 132 bits (332), Expect = 8e-31
Identities = 87/305 (28%), Positives = 154/305 (49%), Gaps = 29/305 (9%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
++IG+G +G V + Q A+KK+ ++E + RE+ +L+ HPN+
Sbjct: 8 EKIGEGTYGVVYKGRHKTTGQV----VAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Query: 85 VKLEYFYTHISPTDHKLY---QHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
V L+ + D +LY + L+M+ + +Y ++L VK Y YQI
Sbjct: 64 VSLQ----DVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSL------VKSYLYQIL 113
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRAP 200
+G+++ H+ + HRD+KP N+L+D + G +K+ DFG A+ ++ + + +YR+P
Sbjct: 114 QGIVFCHSRRVLHRDLKPQNLLIDDK-GTIKLADFGLARAFGIPIRVYTHEVVTLWYRSP 172
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+++G +Y+T +DIW +G + E+ K +F G + QL I + LG P+
Sbjct: 173 EVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVW---- 228
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFD 320
P K F + +G+DLL +L+Y+P +R S + L HP+F+
Sbjct: 229 PEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
Query: 321 DLRNE 325
DL N+
Sbjct: 289 DLDNQ 293
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 132 bits (332), Expect = 8e-31
Identities = 90/290 (31%), Positives = 149/290 (51%), Gaps = 24/290 (8%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADH 81
++ ++IGQG + +V +A + A+KKV P + +RE+ ILR +H
Sbjct: 106 QKLEKIGQGTYSSVFRAREVETGKM----VALKKVKFDNLQPESIRFMAREILILRKLNH 161
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
PN++KLE T + + L L + N +R+ + +K Y Q+
Sbjct: 162 PNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIRFTE-------PQIKCYMKQLL 214
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLE-SNQPSI-SYICSRYYRA 199
G+ + H G+ HRDIK SN+LV+ + G+LK+ DFG A + SN+ + S + + +YRA
Sbjct: 215 WGLEHCHMRGVIHRDIKASNILVNNK-GVLKLGDFGLANVVTPSNKNQLTSRVVTLWYRA 273
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFS 259
PEL++G T Y +D+W +GCV E+L+GK + +G + QLH+I KL G P F +
Sbjct: 274 PELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQLHKIYKLCGSPQDSFWKRT 333
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRAS 309
+ + +E + R + GV LL ++L EP++R +
Sbjct: 334 KLPHATSFKPQHTYEATLRERCKD----LSATGVYLLETLLSMEPDKRGT 379
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 132 bits (331), Expect = 1e-30
Identities = 90/322 (27%), Positives = 159/322 (48%), Gaps = 37/322 (11%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILRIAD 80
++ +++G+G +G V +A +K G A+KK + + + RE+ +L++
Sbjct: 5 EKLEKVGEGTYGKVYKAM-----EKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 81 HPNVVKLEYFYTHISPTDHKLYQH-------LAMECLPEMLQNEILRYKKNNLELPLKH- 132
+ H+ + H L E L L+ I ++K + PL+
Sbjct: 60 QSIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEAS 119
Query: 133 -VKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY 191
V+ + +Q+ +G+ + H+ G+ HRD+KP N+L+D GILKI D G ++ + ++
Sbjct: 120 LVQRFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTH 179
Query: 192 -ICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP 250
I + +YRAPE+++G T Y+T +DIW +GC+ EM+ +A+F G QL I +LLG
Sbjct: 180 EIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGT 239
Query: 251 PDKRFIFFSNPSYNGPLFSK-----PLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPE 305
P ++ + G + + P +E +R P+G+DLL +L Y P
Sbjct: 240 PTEQ-------QWPGVMALRDWHVYPKWEPQDLSRAVPSL---SPEGIDLLTQMLKYNPA 289
Query: 306 RRASPRRILAHPFFDDLRNERY 327
R S + L HP+FD L ++
Sbjct: 290 ERISAKAALDHPYFDSLDKSQF 311
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 132 bits (331), Expect = 1e-30
Identities = 107/361 (29%), Positives = 168/361 (45%), Gaps = 53/361 (14%)
Query: 7 DEYVAHDVISNKSNVKREM-------LVKEYKR---IGQGAFGTVVQAYLTPDNQKWLGP 56
DEYV H+ S R + V E++R I +G +G V +A ++K
Sbjct: 376 DEYVRHETPEPASTPLRSINMLQGCRSVDEFERLNKIDEGTYGVVYRA----KDKKTGEI 431
Query: 57 FAIKKVPAQTEYKS------RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECL 110
A+KKV + E + RE+ IL HP++V ++ S + L
Sbjct: 432 VALKKVKMEKEREGFPLTSLREINILLSFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDL 491
Query: 111 PEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGI 170
+++ R+ ++ VK Q+ G+ YLH + HRD+K SN+L++ + G
Sbjct: 492 KALMETMKQRFSQSE-------VKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNR-GE 543
Query: 171 LKICDFGSAKKLESN-QPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGK 229
LKICDFG A++ S +P + + +YRAPEL++G QY+T ID+W LGC++ E+L+
Sbjct: 544 LKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQYSTAIDMWSLGCIMAELLMKA 603
Query: 230 AVFQGHQPLLQLHEITKLLGPPDKRF-----------IFFSNPSYN--GPLFSKPLFEGA 276
+F G QL +I ++LG P++ + F YN F F GA
Sbjct: 604 PLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVNFVKHQYNLLRKKFPATSFTGA 663
Query: 277 PKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDD--LRNERYFFPSGSS 334
P G DLL +L Y+PERR + L H +F + L + F P+ +
Sbjct: 664 P---------VLSDAGFDLLNKLLTYDPERRITVNEALKHDWFREVPLPKSKDFMPTFPA 714
Query: 335 Q 335
Q
Sbjct: 715 Q 715
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 132 bits (331), Expect = 1e-30
Identities = 94/304 (30%), Positives = 148/304 (47%), Gaps = 28/304 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ R+G+G++G V +A T N+ A+KKV E RE+ IL+ H
Sbjct: 54 EKLNRVGEGSYGIVYRARDTRSNEI----VALKKVRMDQEKDGLPISGLREIMILKQCHH 109
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
N+V+L S L + L +L N + ++ VK Q+
Sbjct: 110 ENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESE-------VKCITLQVL 162
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRYYRAP 200
+ + YLH+ + HRD+K SN+L+ + G +K+ DFG A+ + +P + + +YRAP
Sbjct: 163 KALKYLHSRFMIHRDLKVSNLLMTDK-GCIKVADFGLARMFSNPPKPMTPQMVTLWYRAP 221
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--FF 258
EL++GC +TT +D+W GC+LGE+LLGK + G+ + QL I LLG P + F
Sbjct: 222 ELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFA 281
Query: 259 SNPS-YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
P+ N L +P PK F G G +LL + +Y P+ RA+ L
Sbjct: 282 DLPAVQNFTLSQQPYNNLTPK------FHMIGQSGRNLLNILFIYNPKTRATAEECLKSK 335
Query: 318 FFDD 321
+F D
Sbjct: 336 YFVD 339
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 131 bits (330), Expect = 1e-30
Identities = 97/329 (29%), Positives = 162/329 (48%), Gaps = 48/329 (14%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
+RIG+G +G V +A DN K A+K + + + RE+ ++ H N+
Sbjct: 49 RRIGEGTYGVVFKAIHVRDNVKC----ALKMIRTDRDEEGIPSTCLREISCIKDLQHDNI 104
Query: 85 VKL-------------EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLK 131
V L F+ S ++ KLY + E + L+N + + N LP
Sbjct: 105 VTLFDIIYASHFLNYNNIFFEKFS-SNSKLY--MVFEFIDRDLKNLLEMLEPTNSVLPPN 161
Query: 132 HVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY 191
+VK + +Q+ + Y H I HRD+KP N+LV +G++KI DFG A+ PS +Y
Sbjct: 162 YVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVS-DSGVIKIADFGLARNFSF--PSRNY 218
Query: 192 ---ICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLL 248
+ + +YR PE+++G +Y+T +D+W LGC+ E+ K +F G + QL +I +++
Sbjct: 219 THEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIV 278
Query: 249 GPPDKRFIFFSNPSYNGPLFSKPLFEGAP--KARFEKYFGYAGPDGVDLLMSVLVYEPER 306
G P+ + S P + K +F P + E+ G +G+D+L +L Y PER
Sbjct: 279 GTPNIK----SWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTG-NGLDVLREILRYPPER 333
Query: 307 RASPRRILAHPFFDDLRNERYFFPSGSSQ 335
R + + L+H RYF +G +Q
Sbjct: 334 RLTAKGALSH---------RYFLQNGFTQ 353
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 131 bits (330), Expect = 1e-30
Identities = 86/305 (28%), Positives = 152/305 (49%), Gaps = 17/305 (5%)
Query: 16 SNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-RELE 74
S N+ R ++ K R+G G FG V+ A + KK + E S RE++
Sbjct: 37 SKTDNIFRYLMTK---RLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVK 93
Query: 75 ILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVK 134
L+ +HPN++KL + + LY E + E L + K + P ++
Sbjct: 94 SLKKLNHPNIIKLR----EVIRENDILY--FVFEFMQENLYELM---KDRDRYFPESVIR 144
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICS 194
YQ+ +G+ ++H G HRD+KP N++ + T ++KI DFG A+++ S P Y+ +
Sbjct: 145 NIIYQVLQGLAFMHKNGFFHRDMKPENIMCNG-TELVKIADFGLAREIRSKPPYTDYVST 203
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
R+YRAPE+++ T Y + ID+W LGC++ E+ + + +F G + QL +I +LG P+K
Sbjct: 204 RWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKD 263
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
Y F+ E+ +G+ L+M ++++ PE+R + + L
Sbjct: 264 ---EWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSL 320
Query: 315 AHPFF 319
+ +F
Sbjct: 321 RYKYF 325
>CE05866 [G] KOG0658 Glycogen synthase kinase-3
Length = 399
Score = 131 bits (330), Expect = 1e-30
Identities = 87/305 (28%), Positives = 146/305 (47%), Gaps = 22/305 (7%)
Query: 20 NVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIA 79
N K + ++E G F V + L ++K + AIKK + E R E + +
Sbjct: 16 NKKVMLKIEEVHLHSCGVFSNVYKGILREPHEKNI---AIKK--SWPEKGERNFEFIFLT 70
Query: 80 D-----HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVK 134
H NV+ + + ++H T K+ + + +P L E++R K +L+ ++
Sbjct: 71 GRERTKHKNVIHMIFAFSHSYGT--KVCESYVFDYMPNTLA-EVIRQKLTDLD-----IR 122
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICS 194
LY +QI G+ YL + HRD+KP N+LVD TG LKI DFGS K + + + Y +
Sbjct: 123 LYTWQIFSGLKYLEEHRVVHRDLKPVNILVDHDTGFLKISDFGSVKIIVKGKANNHYQVT 182
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
R+YR PEL+ +Y +D+W GC++ EM+ + VF G Q+ + G P ++
Sbjct: 183 RFYRPPELLQKAMEYNCTVDVWSAGCIMAEMVKRRVVFPGRDSAQQMKLYCRCFGVPTEQ 242
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
I + G L++ ++ PD + + +LVY PE+R +++L
Sbjct: 243 DIL----AMKGERLENELWKFTKGFGLQRLVTEITPDQLQFIKRILVYTPEKRLHGKQLL 298
Query: 315 AHPFF 319
FF
Sbjct: 299 QDDFF 303
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 131 bits (330), Expect = 1e-30
Identities = 93/324 (28%), Positives = 164/324 (49%), Gaps = 46/324 (14%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
++IG+G +G V + N++ A+KK+ ++E + RE+ +L+ HPNV
Sbjct: 26 EKIGEGTYGVVYKG----KNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNV 81
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN---NLELPLKHVKLYAYQIA 141
V LE + Q + + E L ++ RY + LPL+ +K Y +QI
Sbjct: 82 VGLEAV----------IMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQIL 131
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRAP 200
+ M + H + HRD+KP N+LVD G +K+ DFG A+ + ++ + + +YRAP
Sbjct: 132 QAMCFCHQRRVIHRDLKPQNLLVD-NNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAP 190
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+++G +Y+ +D+W +GC+ EM K +FQG + +L I ++LG P +
Sbjct: 191 EILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTP-------TE 243
Query: 261 PSYNGPLFSKPLFEGA-PKAR--------FEKYFG--YAGPDGVDLLMSVLVYEPERRAS 309
+NG + S P ++ PK R ++K G LL +L+Y+P R +
Sbjct: 244 LEWNG-VESLPDYKATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLN 302
Query: 310 PRRILAHPFFDDLRNERYFFPSGS 333
++ L HP+FD++ + P+G+
Sbjct: 303 AKKALVHPYFDNMDTSK--LPAGN 324
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 131 bits (330), Expect = 1e-30
Identities = 98/329 (29%), Positives = 164/329 (49%), Gaps = 32/329 (9%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEI 75
+R ++ ++IGQG + +V +A N+ A+KKV ++ +RE+ +
Sbjct: 208 RRANTFEKLEKIGQGTYSSVYRARDLLHNKI----VALKKVRFDLNDMESVKFMAREIIV 263
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKK-NNLELPLKHVK 134
+R DHPNV+KLE T +P LY + E + +++L ++ VK
Sbjct: 264 MRRLDHPNVLKLEGLIT--APVSSSLY------LVFEYMDHDLLGLSSLPGVKFTEPQVK 315
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLE--SNQPSISYI 192
Y Q+ G+ + H+ G+ HRDIK SN+L+D + G+LKI DFG A + + S++
Sbjct: 316 CYMRQLLSGLEHCHSRGVLHRDIKGSNLLIDSK-GVLKIADFGLATFFDPAKSVSLTSHV 374
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+ +YR PEL++G + Y +D+W GC+LGE+ GK + G + QLH+I KL G P
Sbjct: 375 VTLWYRPPELLLGASHYGVGVDLWSTGCILGELYAGKPILPGKTEVEQLHKIFKLCGSPT 434
Query: 253 KRFIFFSN-PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPR 311
+ + PS G + P + + + F + LL ++L +P+ R+S
Sbjct: 435 ENYWRKQKLPSSAGFKTAIPY-----RRKVSEMFKDFPASVLSLLETLLSIDPDHRSSAD 489
Query: 312 RILAHPFFDDLRNERYFFPSGSSQPKHLP 340
R L +F + F S+ PK+ P
Sbjct: 490 RALESEYF----KTKPFACDPSNLPKYPP 514
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 131 bits (329), Expect = 2e-30
Identities = 94/305 (30%), Positives = 159/305 (51%), Gaps = 27/305 (8%)
Query: 28 KEYKRIGQGAFGTVVQAY-LTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIAD 80
K +++G+G +G V +A L P + + A+KK+ ++E + RE+ +L+
Sbjct: 9 KRLEKVGEGTYGVVYKALDLRPGQGQRV--VALKKIRLESEDEGVPSTAIREISLLKELK 66
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN---NLELPLKHVKLYA 137
N+V+L Y + HKLY + E L ++ RY + + L VK +
Sbjct: 67 DDNIVRL---YDIVHSDAHKLY------LVFEFLDLDLKRYMEGIPKDQPLGADIVKKFM 117
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRY 196
Q+ +G+ Y H+ I HRD+KP N+L++ + G LK+ DFG A+ + ++ I + +
Sbjct: 118 MQLCKGIAYCHSHRILHRDLKPQNLLIN-KDGNLKLGDFGLARAFGVPLRAYTHEIVTLW 176
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI 256
YRAPE+++G QY+T +D W +GC+ EM K +F G + Q+ +I ++LG P++
Sbjct: 177 YRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNE--A 234
Query: 257 FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAH 316
+ + Y P F KP F + + P G+DLL +L Y+P R S RR H
Sbjct: 235 IWPDIVYL-PDF-KPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIH 292
Query: 317 PFFDD 321
P+F +
Sbjct: 293 PYFQE 297
>CE20405 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 131 bits (329), Expect = 2e-30
Identities = 99/317 (31%), Positives = 143/317 (44%), Gaps = 32/317 (10%)
Query: 36 GAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIAD---HPNVVKLEYFYT 92
GAF V + ++ + + IKK + + E++IL H N+V+L Y Y
Sbjct: 35 GAFSNVYRGVAQTESNQEID-IVIKKTWPRHKGCPMEVKILGQLGKLKHRNIVRLLYSYQ 93
Query: 93 HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHALGI 152
+ ++ L E +P L + K N + + VKL +Q+ RG +L I
Sbjct: 94 --KQHEGRICLALIFEYIPLNLYQFL---KDKNRRIDIVEVKLIVWQLFRGQAHLEKADI 148
Query: 153 CHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTTK 212
CHRDIKP N+L + +TG+LKI DFGS+ + P SY +RYYR PELI+G Y K
Sbjct: 149 CHRDIKPQNLLYNAETGLLKISDFGSSSIQSTKSPQQSYHVTRYYRPPELILGSKYYGCK 208
Query: 213 IDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP---DKRFIFFSNPSYNGPLFS 269
ID W GCV GE+L G + G Q I +LG P D + S+ L S
Sbjct: 209 IDTWSCGCVFGELLKGGIILAGKSSNNQAEVIFDMLGYPTDSDVSSMKVSSTKLQEVLDS 268
Query: 270 KPLFEGAPKARFEKYFGYA--------------------GPDGVDLLMSVLVYEPERRAS 309
+ A + + V +L+ +LVY P +R S
Sbjct: 269 YEYNKSKTTADLTYLYTQTVIYQKDRRTTVYNTKIEQDDMKESVAVLLQILVYNPNKRLS 328
Query: 310 PRRILAHPFFDDLRNER 326
IL HP+F+ L NE+
Sbjct: 329 GIEILTHPYFNVLFNEK 345
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 130 bits (328), Expect = 2e-30
Identities = 88/316 (27%), Positives = 154/316 (47%), Gaps = 33/316 (10%)
Query: 13 DVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-- 70
++++++ +M ++ + IG+G FG V+ A +K +A+KKV + E S
Sbjct: 8 EILAHRRFTATKMEYEKIRIIGEGTFGQVILA------RKGRARYALKKVSKEKEGLSVT 61
Query: 71 --RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLEL 128
RE+++LR HP++V+L + ++ + + N +R K +
Sbjct: 62 TIREVQVLRAMGHPSIVRLIEVVVEPGGDIYMVFPYFPYDL------NRFIRSNK----M 111
Query: 129 PLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS 188
+K YQIA+G+ Y+H+ GI HRD+K +N+L+D + I DFG A+
Sbjct: 112 TCSEIKHIFYQIAQGVCYIHSKGIMHRDLKSANILLDQKLNA-SIADFGMARYTTKTGAY 170
Query: 189 ISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLL 248
+ + +YRAPE+++G + YT +DIW LGC+L EM LG +FQG +LQL +
Sbjct: 171 TPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHAC 230
Query: 249 GPPDKRFIFFSNPSYNG----PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEP 304
G + SY G P F +P+ R E V+L+ +L +P
Sbjct: 231 GS-------INENSYPGVQDLPGFRNFRLPQSPR-RIEGIIRKHDASAVELVSKMLCLDP 282
Query: 305 ERRASPRRILAHPFFD 320
+R + +++ +F+
Sbjct: 283 SKRITVEQVVGSKYFE 298
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 130 bits (328), Expect = 2e-30
Identities = 92/299 (30%), Positives = 151/299 (49%), Gaps = 27/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQT------EYKSRELEILRIADHPNV 84
+IG G + V +A G A+KKV ++ +RE+ ILR DHPNV
Sbjct: 143 KIGSGTYSNVYKA-----KDSLTGNIVALKKVRCDVNERESLKFMAREILILRRLDHPNV 197
Query: 85 VKLEYFYT-HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
+KLE T +S + + +++++ + EI + + VK Y Q+ G
Sbjct: 198 IKLEGLVTSRMSSSLYLVFRYMDHDLAGLAASPEI--------KFTEQQVKCYMKQLLSG 249
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN--QPSISYICSRYYRAPE 201
+ + H G+ HRDIK SN+L+D G+L+I DFG A +++ Q + + + +YR+PE
Sbjct: 250 LEHCHNRGVLHRDIKGSNLLID-DGGVLRIGDFGLATFFDASKRQEMTNRVVTLWYRSPE 308
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF-IFFSN 260
L+ G +Y+ +D+W GC+L E+L G+A+ G + QLH I KL G P + +
Sbjct: 309 LLHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRL 368
Query: 261 PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
PS + KPL + K R + + P+ + LL ++L +P R + +L FF
Sbjct: 369 PSTHKHAHHKPLPQ--YKRRIREVYKDFSPEALSLLDTLLALDPAERQTATDVLMSDFF 425
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 130 bits (328), Expect = 2e-30
Identities = 79/238 (33%), Positives = 128/238 (53%), Gaps = 22/238 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADH 81
++ ++IGQG + V +A T + A+KKV P ++ +RE+ ILR +H
Sbjct: 122 EKLEKIGQGTYSNVFRAVETETGRI----VALKKVRFDNFEPESVKFMAREILILRRLNH 177
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
PN++KLE T + +L L +L + +++ +K Y Q+
Sbjct: 178 PNIIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTT-------PQIKCYMKQLL 230
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN----QPSISYICSRYY 197
G+ + H+ G+ HRDIK SN+L+ + GILK+ DFG A S+ +P S + + +Y
Sbjct: 231 SGLDHCHSRGVMHRDIKGSNLLLSNE-GILKVADFGLANFSNSSGHKKKPLTSRVVTLWY 289
Query: 198 RAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
R PEL++G T Y +D+W +GCV E+LLGK + +G + QLH+I KL G P + +
Sbjct: 290 RPPELLLGATDYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDY 347
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 130 bits (328), Expect = 2e-30
Identities = 94/308 (30%), Positives = 147/308 (47%), Gaps = 37/308 (12%)
Query: 21 VKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELE 74
+KRE+L GQG +G V +A T + + AIKK+ E + RE++
Sbjct: 12 LKREVL-------GQGTYGVVFKATDTKNGET----VAIKKIRLGKEKEGVNVTALREIK 60
Query: 75 ILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVK 134
+L+ HP++++L I HK H+ E + L+ I + NL L VK
Sbjct: 61 LLKELKHPHIIEL------IDAFPHKENLHIVFEFMETDLEAVI---RDRNLYLSPGDVK 111
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-IC 193
Y I +G+ Y H + HRD+KP+N+L+ P G LK+ DFG A+ S ++ +
Sbjct: 112 SYLQMILKGLEYCHGKWVLHRDMKPNNLLIGPN-GQLKLADFGLARIFGSPGRKFTHQVF 170
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP-- 251
+R+YRAPEL+ G QY +D+W GC+ E+LL + QG+ + QL +I G P
Sbjct: 171 ARWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKA 230
Query: 252 DKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPR 311
D+ P Y ++ P D +DLL + Y+P+ R S +
Sbjct: 231 DQWPDMICLPDY-------VEYQFVPAPSLRSLLPTVSEDALDLLSKMFTYDPKSRISIQ 283
Query: 312 RILAHPFF 319
+ L H +F
Sbjct: 284 QALKHRYF 291
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 130 bits (328), Expect = 2e-30
Identities = 95/311 (30%), Positives = 150/311 (47%), Gaps = 42/311 (13%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEILRIADHPNVVK 86
IG GA G V AY T Q AIKK+ + RE +++++ +H N++
Sbjct: 30 IGSGAQGIVCAAYDTITQQN----VAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIG 85
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L +T + +L ME + L I ++L + YQ+ G+ +
Sbjct: 86 LLNAFTPQRNLEEFQDVYLVMELMDANLCQVI------QMDLDHDRMSYLLYQMLCGIKH 139
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
LH+ GI HRD+KPSN++V LKI DFG A+ + Y+ +RYYRAPE+I+G
Sbjct: 140 LHSAGIIHRDLKPSNIVVKADC-TLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGM 198
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGP 266
YT +DIW +GC++GEM+ G +F G + Q ++I + LG P F+ P+
Sbjct: 199 G-YTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNY 257
Query: 267 LFSKPLFEGAPKARFEKYFGYAGPDGV-----------------DLLMSVLVYEPERRAS 309
+ ++P + G F++ F PDG+ +LL +LV +PE+R S
Sbjct: 258 VENRPRYTG---YSFDRLF----PDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRIS 310
Query: 310 PRRILAHPFFD 320
L H + +
Sbjct: 311 VDEALKHEYIN 321
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 130 bits (327), Expect = 3e-30
Identities = 101/307 (32%), Positives = 150/307 (47%), Gaps = 26/307 (8%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEI 75
+R ++ ++IGQG + V +A + A+KKV ++ +RE+ +
Sbjct: 109 RRATTYEKLEKIGQGTYSNVYKAKDLLSGKI----VALKKVRFDNLEAESVKFMAREILV 164
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKL 135
LR +HPNV+KL+ T S LY L E + L L+ L VK
Sbjct: 165 LRRLNHPNVIKLQGLVT--SRVSCSLY--LVFEYMEHDLSGLAAT---QGLKFDLPQVKC 217
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI--SYIC 193
+ Q+ G+ + H+ G+ HRDIK SN+L+D GILKI DFG A + Q S +
Sbjct: 218 FMKQLLSGLEHCHSRGVLHRDIKGSNLLID-NDGILKIADFGLATFYDPKQKQTMTSRVV 276
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPD 252
+ +YR PEL++G T Y T +D+W GC++ E+L GK V G + QLH+I KL G P D
Sbjct: 277 TLWYRPPELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSD 336
Query: 253 KRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
+ + P N LF KP + K + F P V L+ ++L +P R +
Sbjct: 337 SYWKKYRLP--NATLF-KP--QHPYKRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTS 391
Query: 313 ILAHPFF 319
L FF
Sbjct: 392 ALNSEFF 398
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 130 bits (326), Expect = 4e-30
Identities = 98/309 (31%), Positives = 149/309 (47%), Gaps = 36/309 (11%)
Query: 28 KEYKRI---GQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA--QTEYKS-------RELEI 75
K Y+++ G+G F TV +A NQ AIKK+ ++E K RE+++
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQI----VAIKKIKLGHRSEAKDGINRTALREIKL 65
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKL 135
L+ HPN++ L + HK L + + L+ I K N+L L H+K
Sbjct: 66 LQELSHPNIIGL------LDAFGHKSNISLVFDFMETDLEVII---KDNSLVLTPSHIKA 116
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICS 194
Y +G+ YLH I HRD+KP+N+L+D + G+LK+ DFG AK S N+ + +
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLD-ENGVLKLADFGLAKSFGSPNRAYTHQVVT 175
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
R+YRAPEL+ G Y +D+W +GC+L E+LL G L QL I + LG P +
Sbjct: 176 RWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 235
Query: 255 F--IFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
S P Y F+ P F AG D +DL+ + ++ P R + +
Sbjct: 236 QWPDMCSLPDY-------VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQ 288
Query: 313 ILAHPFFDD 321
L +F +
Sbjct: 289 ALKMKYFSN 297
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 130 bits (326), Expect = 4e-30
Identities = 95/297 (31%), Positives = 143/297 (47%), Gaps = 29/297 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSR---------ELEILRIADHPN 83
+G+G F TV +A T NQ A+KK+ + +R E++IL+ H N
Sbjct: 18 LGEGQFATVYKARDTVTNQI----VAVKKIKKGSREDARDGINRTALREIKILQELQHEN 73
Query: 84 VVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
++ L + +S L + + L+ I K N + L ++K YA +G
Sbjct: 74 IIGLVDVFGQLSNVS------LVFDFMDTDLEVII---KDNKIILTQANIKAYAIMTLKG 124
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICSRYYRAPEL 202
+ YLH I HRD+KP+N+LV+ GILKI DFG AK S N+ ++ +R+YR+PEL
Sbjct: 125 LEYLHLNWILHRDLKPNNLLVNSD-GILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPEL 183
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
+ G QY T +D+W +GC+L E++L G L QL I LG P + +
Sbjct: 184 LFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTE-----AEWP 238
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ L F P + F AG D + L+ + P RR S R L+ P+F
Sbjct: 239 HLSKLHDYLQFRNFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 129 bits (325), Expect = 5e-30
Identities = 95/305 (31%), Positives = 150/305 (49%), Gaps = 27/305 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY ++ AIKK+ QT K REL +++ +H N+
Sbjct: 68 KPIGSGAQGIVCAAYDAVLDRN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 123
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + +L ME + L I +EL + + YQ+ G+
Sbjct: 124 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 177
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 178 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 236
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +DIW +GC++GEM+ K +F G + Q +++ + LG P F+ P+
Sbjct: 237 GMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 295
Query: 265 GPLFSKPLFEGA------PKARF---EKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
+ ++P + G P + F ++ DLL +LV +P +R S L
Sbjct: 296 NYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQ 355
Query: 316 HPFFD 320
HP+ +
Sbjct: 356 HPYIN 360
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 129 bits (325), Expect = 5e-30
Identities = 95/305 (31%), Positives = 150/305 (49%), Gaps = 27/305 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY ++ AIKK+ QT K REL +++ +H N+
Sbjct: 68 KPIGSGAQGIVCAAYDAVLDRN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 123
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + +L ME + L I +EL + + YQ+ G+
Sbjct: 124 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 177
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 178 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 236
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +DIW +GC++GEM+ K +F G + Q +++ + LG P F+ P+
Sbjct: 237 GMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 295
Query: 265 GPLFSKPLFEGA------PKARF---EKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
+ ++P + G P + F ++ DLL +LV +P +R S L
Sbjct: 296 NYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQ 355
Query: 316 HPFFD 320
HP+ +
Sbjct: 356 HPYIN 360
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 129 bits (325), Expect = 5e-30
Identities = 95/305 (31%), Positives = 150/305 (49%), Gaps = 27/305 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY ++ AIKK+ QT K REL +++ +H N+
Sbjct: 30 KPIGSGAQGIVCAAYDAVLDRN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + +L ME + L I +EL + + YQ+ G+
Sbjct: 86 ISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 139
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 140 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +DIW +GC++GEM+ K +F G + Q +++ + LG P F+ P+
Sbjct: 199 GMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 265 GPLFSKPLFEGA------PKARF---EKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
+ ++P + G P + F ++ DLL +LV +P +R S L
Sbjct: 258 NYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQ 317
Query: 316 HPFFD 320
HP+ +
Sbjct: 318 HPYIN 322
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 129 bits (325), Expect = 5e-30
Identities = 92/328 (28%), Positives = 162/328 (49%), Gaps = 44/328 (13%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPF----AIKKVPAQTEYKS-------RELEILRIA 79
K +G G FG V +A N+ F AIK++ + +Y S RE++ L
Sbjct: 8 KEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRM--KKKYFSWEECVNLREVKSLSRM 65
Query: 80 DHPNVVKLEYFYTHISPTDHKLYQHLAMEC-LPEMLQNEILRYKKNNLELPLKHVKLYAY 138
+HPN+VKL+ I D + MEC L +++++ + +++ ++ + +
Sbjct: 66 NHPNIVKLKEV---IRENDILYFVFEYMECNLYQLMKDRPKHFAESD-------IRNWCF 115
Query: 139 QIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYR 198
Q+ +G+ Y+H G HRD+KP N+LV ++KI D G A++++S+ P Y+ +R+YR
Sbjct: 116 QVFQGLSYMHQRGYFHRDLKPENLLVSKD--VIKIADLGLAREIDSSPPYTEYVSTRWYR 173
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR---- 254
APE+++ YT+K+D+W +G ++ E+L + +F G ++++I ++G P +
Sbjct: 174 APEVLLQSYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLE 233
Query: 255 -FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRI 313
S +Y P F P YA D V+L+ + ++P R +
Sbjct: 234 GLNLASVINYQFPQF--------PGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEA 285
Query: 314 LAHPFFDDLRNERYFFPSGSSQPKHLPP 341
L HPFF Y+ P S +PK P
Sbjct: 286 LQHPFFQSC----YYIPP-SLRPKLSEP 308
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 129 bits (325), Expect = 5e-30
Identities = 101/332 (30%), Positives = 160/332 (47%), Gaps = 38/332 (11%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP------AQTEYKSRELEI 75
+R ++ ++IGQG + +V +A +N+ A+K+V ++ +RE+ +
Sbjct: 132 RRASTFEKLEKIGQGTYSSVYKARDLTNNKI----VALKRVRFDLSDLESVKFMAREIIV 187
Query: 76 LRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKK-NNLELPLKHVK 134
+R DHPNV+KLE T + LY + E + ++++ ++ VK
Sbjct: 188 MRRLDHPNVLKLEGLIT--ASVSSSLY------LVFEYMDHDLVGLASIPGIKFSEPQVK 239
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQ--PSISYI 192
Y Q+ G+ + H+ G+ HRDIK SN+L+D G+LKI DFG A + P S +
Sbjct: 240 CYMQQLLSGLHHCHSRGVLHRDIKGSNLLID-SNGVLKIADFGLATFFDPQNCVPLTSRV 298
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+ +YR PEL++G Y +D+W GC+LGE+ GK + G + QLH+I KL G P
Sbjct: 299 VTLWYRPPELLLGACHYGVGVDLWSTGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPT 358
Query: 253 KRFIFFSNPSYNGPLFSKPLFEGAPK----ARFEKYFGYAGPDGVDLLMSVLVYEPERRA 308
+ Y L P P R + F + + LL ++L +P+RR
Sbjct: 359 E--------DYWRKLKLPPSAAFRPALPYGRRVAEMFKDLPTNVLSLLEALLSIDPDRRG 410
Query: 309 SPRRILAHPFFDDLRNERYFFPSGSSQPKHLP 340
S R L +F R E F SS PK+ P
Sbjct: 411 SAARALESEYF---RTEP-FACDPSSLPKYPP 438
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 129 bits (325), Expect = 5e-30
Identities = 92/301 (30%), Positives = 149/301 (48%), Gaps = 26/301 (8%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADH 81
++ ++IGQG + +V +A NQ A+KKV P + +RE+ ILR DH
Sbjct: 164 EKLEKIGQGTYSSVYKARDLETNQL----VALKKVRFANMDPDSVRFMAREIIILRRLDH 219
Query: 82 PNVVKLEYFYT-HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
PNV+KLE T +S + + +++++ + L + + + + +K Y Q+
Sbjct: 220 PNVMKLEGLITSRVSGSMYLIFEYMEHD-LAGLASTPGINFSE-------AQIKCYMKQL 271
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQ--PSISYICSRYYR 198
G+ + H+ G+ HRDIK SN+L+D LKI DFG A + +Q P S + + +YR
Sbjct: 272 LHGLEHCHSRGVLHRDIKGSNLLLDHNNN-LKIGDFGLANFYQGHQKQPLTSRVVTLWYR 330
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFF 258
PEL++G T Y +D+W GC+L E+ GK + G + QLH+I KL G P + +
Sbjct: 331 PPELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEYWKI 390
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
S + KP + K + F + L+ +L EP+ R + L F
Sbjct: 391 SKLPH--ATIFKP--QQPYKRCVAETFKSLPSSALALVEVLLAVEPDARGTTASALESEF 446
Query: 319 F 319
F
Sbjct: 447 F 447
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 129 bits (324), Expect = 7e-30
Identities = 94/324 (29%), Positives = 159/324 (49%), Gaps = 29/324 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILR---IADHPN 83
IG+GA+G V +A + +++ A+K+V QT + RE+ +LR +HPN
Sbjct: 19 IGEGAYGKVFKARDLKNGGRFV---ALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPN 75
Query: 84 VVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
VV+L T +S TD + L E + + L + + + + P + +K +Q+ RG
Sbjct: 76 VVRLFDVCT-VSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGV--PTETIKDMMFQLLRG 132
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
+ +LH+ + HRD+KP N+LV +G +K+ DFG A+ S + + +YRAPE++
Sbjct: 133 LDFLHSHRVVHRDLKPQNILVT-SSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVL 191
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSY 263
+ + Y T +D+W +GC+ EM K +F+G + QL +I ++G P +
Sbjct: 192 LQ-SSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE------EDWP 244
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLR 323
+ F EK+ G DLL+ L + P +R S L+HP+F DL
Sbjct: 245 RDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304
Query: 324 NERYFFPSGSSQPKHLPPLYDFSD 347
+ + HLPP + S+
Sbjct: 305 RCK------ENLDSHLPPSQNTSE 322
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 129 bits (323), Expect = 9e-30
Identities = 90/312 (28%), Positives = 149/312 (46%), Gaps = 44/312 (14%)
Query: 27 VKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-------RELEILRIA 79
VKE +++G+G + V N++ AIKK+ ++K RE++ LR +
Sbjct: 12 VKE-RKVGEGTYAVVFLGRQKETNRR----VAIKKIKVG-QFKDGIDISALREIKFLRES 65
Query: 80 DHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLK-------- 131
H NV++L + T L N IL + ++LE+ +K
Sbjct: 66 RHDNVIEL----VDVFSTKSNL--------------NIILEFLDSDLEMLIKDKFIVFQP 107
Query: 132 -HVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS 190
H+K + + RG+ ++H+ I HRD+KP+N+L+ G+LK+ DFG ++ +
Sbjct: 108 AHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSD-GVLKLADFGLSRDFGTPSHMSH 166
Query: 191 YICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP 250
+ +R+YR PEL +GC Y T +D+W +GC+ E++L G L QL+ I + LG
Sbjct: 167 QVITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGT 226
Query: 251 PDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASP 310
P+ I P + + P E F AG + +DLL +L Y P RR +
Sbjct: 227 PEPEVI---KSMQQLPNYVEMKHIPPPNGGMEALFSAAGHEEIDLLKMMLDYNPYRRPTA 283
Query: 311 RRILAHPFFDDL 322
++ L H +F L
Sbjct: 284 QQALEHHYFSAL 295
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 129 bits (323), Expect = 9e-30
Identities = 89/301 (29%), Positives = 146/301 (47%), Gaps = 27/301 (8%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNVV 85
+IG+G++G V + Q AIKK P + RE+ +L+ HPN+V
Sbjct: 10 KIGEGSYGVVFKCRNRDTGQI----VAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLV 65
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
L + K HL E + +E+ RY++ +P VK +Q + +
Sbjct: 66 NLLEVFRR------KRRLHLVFEYCDHTVLHELDRYQRG---VPEHLVKSITWQTLQAVN 116
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS-YICSRYYRAPELIV 204
+ H HRD+KP N+L+ + ++K+CDFG A+ L + Y+ +R+YR+PEL+V
Sbjct: 117 FCHKHNCIHRDVKPENILITKHS-VIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLV 175
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP--PDKRFIFFSNPS 262
G TQY +D+W +GCV E+L G ++ G + QL+ I K LG P + +F +N
Sbjct: 176 GDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQY 235
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
++G P E F + LL L +P R + ++L HP+F+++
Sbjct: 236 FSGVKIPDP----EDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFENI 291
Query: 323 R 323
R
Sbjct: 292 R 292
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 129 bits (323), Expect = 9e-30
Identities = 92/297 (30%), Positives = 151/297 (49%), Gaps = 26/297 (8%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNVV 85
+IGQG + +V +A + A+KKV P + +RE+ ILR DHPNV+
Sbjct: 152 KIGQGTYSSVYKARDLETGKI----VAMKKVRFVNMDPESVRFMAREILILRKLDHPNVM 207
Query: 86 KLEYFYT-HISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
KLE T +S + + +++++ + L + +++ + +K Y Q+ RG+
Sbjct: 208 KLEGLVTSRLSGSLYLVFEYMEHD-LAGLAATPGIKFSE-------PQIKCYMQQLFRGL 259
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYICSRYYRAPEL 202
+ H GI HRDIK SN+L++ + G+LKI DFG A + + + S + + +YRAPEL
Sbjct: 260 EHCHRRGILHRDIKGSNLLINNE-GVLKIGDFGLANFYRGDGDLQLTSRVVTLWYRAPEL 318
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G T+Y ID+W GC+L E+ GK + G + Q+H+I KL G P + ++ +
Sbjct: 319 LLGATEYGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSED--YWRRAT 376
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
KP P + F + + L+ +L EPE+R S L FF
Sbjct: 377 LPLATSFKPSHPYKPV--LAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFF 431
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 128 bits (321), Expect = 2e-29
Identities = 99/325 (30%), Positives = 161/325 (49%), Gaps = 36/325 (11%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA-----QTEY-----KSRELEILR 77
++ +I +G +G V +A ++K A+KK+ + EY RE+ IL
Sbjct: 298 QKLNKINEGTYGIVYKAR----DEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILL 353
Query: 78 IADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYA 137
+HP +V ++ D+ +Y + ME L L+ + R K+ VK
Sbjct: 354 SCNHPAIVNVKEVVVG-GKNDNDVY--MVMEHLEHDLRGVMDRRKE---PFSTSEVKCLM 407
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRY 196
Q+ G+ YLH I HRD+KPSN+L++ G LKICDFG A++ S +P + +++
Sbjct: 408 MQLLDGLKYLHTNWIIHRDLKPSNLLMN-NCGELKICDFGMARQYGSPIKPYTQMVITQW 466
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI 256
YR PEL++G +Y+T +D+W +GC++ E+L K +F G L QL +I +LG P++
Sbjct: 467 YRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIW 526
Query: 257 FFSNPSYNGPLFSKPLFEGAPKARFEKYF---GYAGPD-----GVDLLMSVLVYEPERRA 308
P ++ +K F P K F + G G DLL S+L +PE+R
Sbjct: 527 ----PGFSSFPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRL 582
Query: 309 SPRRILAHPFFDD--LRNERYFFPS 331
+ L H +F + L + F P+
Sbjct: 583 TVEDALNHGWFHEVPLPKSKDFMPT 607
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 128 bits (321), Expect = 2e-29
Identities = 96/311 (30%), Positives = 163/311 (51%), Gaps = 47/311 (15%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
++IG+G +G V +A Q A+KK+ + E + RE+ +L+ HPNV
Sbjct: 12 EKIGEGTYGIVYKARSNSTGQD----VALKKIRLEGETEGVPSTAIREISLLKNLKHPNV 67
Query: 85 VKLEYFYTHISPTD-HKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
V+L F IS + + ++++L M+ + L KK ++ P + +K Y +QI
Sbjct: 68 VQL--FDVVISGNNLYMIFEYLNMDL-------KKLMDKKKDVFTP-QLIKSYMHQILDA 117
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAP 200
+ + H I HRD+KP N+LVD G +K+ DFG A+ N P +Y + + +YRAP
Sbjct: 118 VGFCHTNRILHRDLKPQNLLVDT-AGKIKLADFGLARAF--NVPMRAYTHEVVTLWYRAP 174
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSN 260
E+++G Y+T +DIW LGC+ EM++ +++F G + QL+ I + L PD+
Sbjct: 175 EILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDET------ 228
Query: 261 PSYNGP-LFSKPLFEGAPKARFEKYFGYAGPDGV------DLLMSVLVYEPERRASPRRI 313
N P + P F K +F ++ G P + +L+MS+L Y+P R S +
Sbjct: 229 ---NWPGVTQLPDF----KTKFPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDA 281
Query: 314 LAHPFFDDLRN 324
L H +F ++++
Sbjct: 282 LQHAYFRNVQH 292
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 127 bits (320), Expect = 2e-29
Identities = 93/297 (31%), Positives = 144/297 (48%), Gaps = 28/297 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV----PAQTEYK--SRELEILRIADHPNVV 85
++G+G++GTV++ K G K+ P Q+ K RE++ L+ H N+V
Sbjct: 9 KVGEGSYGTVMKC-----KHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLV 63
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
L I K HL E + + +E+ Y L K ++ Y +QI R +
Sbjct: 64 NL------IEVFRQKKKIHLVFEFIDHTVLDELQHYCHG---LESKRLRKYLFQILRAID 114
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICSRYYRAPELIV 204
YLH+ I HRDIKP N+LV Q+GI K+CDFG A+ L + Y+ +R+YRAPEL++
Sbjct: 115 YLHSNNIIHRDIKPENILVS-QSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVL 173
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG--PPDKRFIFFSNPS 262
T Y +DIW LGC++ EM G L LH+I +G P + IF +P
Sbjct: 174 KDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPI 233
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ G + + + ++ K G D++ + L +P R S +L H +F
Sbjct: 234 FAGVVLPQVQHPKNARKKYPKLNGLL----ADIVHACLQIDPADRISSSDLLHHEYF 286
>CE05377 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 127 bits (320), Expect = 2e-29
Identities = 93/269 (34%), Positives = 125/269 (45%), Gaps = 28/269 (10%)
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
H N+V+L + Y + ++ L E +P L + K NN + + VKL +Q+
Sbjct: 82 HKNIVRLLFSYQ--KQHEGRICLGLIFEYIPMNLHQFL---KDNNRRVDIIEVKLIVWQL 136
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAP 200
RG +L ICHRDIKP N+L + TG+LKI D+GS+ P SY +RYYR P
Sbjct: 137 FRGQAHLEKSEICHRDIKPQNLLYNADTGLLKISDYGSSAIESVKTPQQSYHVTRYYRPP 196
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP---DKRFIF 257
EL++G Y KID W GCV GE+L G G Q + + G P D +
Sbjct: 197 ELLLGSKNYGCKIDTWSCGCVFGELLKGGIFLAGKSAKNQAEVVFDMFGVPTAEDVSSMN 256
Query: 258 FSNPSYN------GPLFSKPLFEGA----PKARFEK---------YFGYAG-PDGVDLLM 297
SN Y P SK + A A F++ Y+ D V+LL
Sbjct: 257 VSNTKYKEIIQSYEPDTSKRTADLAYLYNQTASFQRDRRSTVYNTKIDYSDMKDSVELLR 316
Query: 298 SVLVYEPERRASPRRILAHPFFDDLRNER 326
VLVY P RR L +PFF L NE+
Sbjct: 317 QVLVYNPSRRLCGIEFLTNPFFTVLFNEK 345
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 127 bits (319), Expect = 3e-29
Identities = 92/301 (30%), Positives = 153/301 (50%), Gaps = 28/301 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
++G+G +G V +A T + +K + A+KK+ Q E + RE+++L+ DHPNV
Sbjct: 188 QVGEGTYGKVYKAKNT-NTEKLV---ALKKLRLQGEREGFPITSIREIKLLQSFDHPNVS 243
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
++ T + ++++ + +L E+ ++ K Q+ GM
Sbjct: 244 TIKEIMVESQKTVYMIFEYADNDLSGLLLNKEV--------QISHSQCKHLFKQLLLGME 295
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVG 205
YLH I HRD+K SN+L+D Q G LKI DFG A+K+ S + + + +YR PEL++G
Sbjct: 296 YLHDNKILHRDVKGSNILIDNQ-GNLKITDFGLARKMNSRADYTNRVITLWYRPPELLLG 354
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS-YN 264
T Y T++D+WG GC+L E+ A+FQG L Q+ I K++G P S P+ Y+
Sbjct: 355 TTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP----TINSWPTLYD 410
Query: 265 GPLFSKPLFEGAPK--ARFEKYFGYAGPDG--VDLLMSVLVYEPERRASPRRILAHPFFD 320
P F + + K F + F P + L +++L Y+ +R S L +F
Sbjct: 411 MPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFK 470
Query: 321 D 321
+
Sbjct: 471 E 471
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 127 bits (319), Expect = 3e-29
Identities = 95/299 (31%), Positives = 152/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 425 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 480
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 481 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 533
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 534 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 590
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 591 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 646
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 647 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 705
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 127 bits (319), Expect = 3e-29
Identities = 95/299 (31%), Positives = 152/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 428 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 483
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 484 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 536
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 537 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 593
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 649
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 650 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 127 bits (319), Expect = 3e-29
Identities = 95/299 (31%), Positives = 152/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 415 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 470
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 471 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 523
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 524 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 580
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 581 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 636
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 637 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 695
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 127 bits (319), Expect = 3e-29
Identities = 95/299 (31%), Positives = 152/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 424 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 479
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 480 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 532
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 533 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 589
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 590 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 645
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 646 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 704
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 127 bits (319), Expect = 3e-29
Identities = 95/299 (31%), Positives = 152/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 45 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 100
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 101 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 153
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 154 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 210
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 211 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 266
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 267 YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 325
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 127 bits (319), Expect = 3e-29
Identities = 96/316 (30%), Positives = 162/316 (50%), Gaps = 42/316 (13%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-----RELEIL 76
K E VK ++G+G + TV + ++ A+K++ + E + RE+ +L
Sbjct: 138 KLETYVK-LDKLGEGTYATVFKGR----SKLTENLVALKEIRLEHEEGAPCTAIREVSLL 192
Query: 77 RIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKH-VKL 135
+ H N+V L + TD L + E L +++ +Y + L H VK+
Sbjct: 193 KNLKHANIVTLH----DLIHTDRSL------TLVFEYLDSDLKQYLDHCGNLMSMHNVKI 242
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---I 192
+ +Q+ RG+ Y H I HRD+KP N+L++ + G LK+ DFG A+ + P+ +Y +
Sbjct: 243 FMFQLLRGLAYCHHRKILHRDLKPQNLLIN-ERGELKLADFGLARA--KSVPTKTYSNEV 299
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+ +YR P++++G T+Y+T ID+WG+GC+ EM G+ +F G +LH I +LLG P
Sbjct: 300 VTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPT 359
Query: 253 KR-----FIFFSNPSYNGPLF-SKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPER 306
+ F +Y+ P + +PL AP+ DG+ LL S+L+YE +
Sbjct: 360 EETWPGVTAFSEFRTYSFPCYLPQPLINHAPR---------LDTDGIHLLSSLLLYESKS 410
Query: 307 RASPRRILAHPFFDDL 322
R S L+H +F L
Sbjct: 411 RMSAEAALSHSYFRSL 426
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 127 bits (318), Expect = 3e-29
Identities = 93/316 (29%), Positives = 160/316 (50%), Gaps = 37/316 (11%)
Query: 32 RIGQGAFGTVVQ--AYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEY 89
++G+G + TV + + LT DN L ++ RE+ +L+ H N+V L
Sbjct: 170 KLGEGTYATVYKGKSKLT-DNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHD 228
Query: 90 FYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN--NLELPLKHVKLYAYQIARGMLYL 147
++ ++ + E L ++ +Y + N+ + + +VKL+ +Q+ RG+ Y
Sbjct: 229 I----------IHTEKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLLRGLAYC 277
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPELIV 204
H + HRD+KP N+L++ + G LK+ DFG A+ + P+ +Y + + +YR P++++
Sbjct: 278 HRQKVLHRDLKPQNLLIN-ERGELKLADFGLARA--KSIPTKTYSNEVVTLWYRPPDILL 334
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--FFSN-- 260
G T Y+T+ID+WG+GC+ EM G+ +F G QLH I ++LG P + SN
Sbjct: 335 GSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEE 394
Query: 261 -PSYNGPLF-SKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
+YN P + ++ L AP+ DG DLL +L +E R S + HPF
Sbjct: 395 FKTYNYPKYRAEALLSHAPR---------LDSDGADLLTKLLQFEGRNRISAEDAMKHPF 445
Query: 319 FDDLRNERYFFPSGSS 334
F L + P +S
Sbjct: 446 FLSLGERIHKLPDTTS 461
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 127 bits (318), Expect = 3e-29
Identities = 94/299 (31%), Positives = 151/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 423 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIV 478
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 479 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 531
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 532 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 588
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 589 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 644
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFG-YAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG G DL+ L Y P RR S L H +F
Sbjct: 645 YSELPVVKKMTFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYF 703
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 127 bits (318), Expect = 3e-29
Identities = 94/299 (31%), Positives = 151/299 (50%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 425 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPNIV 480
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 481 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 533
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + +++YRAPEL
Sbjct: 534 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTQWYRAPEL 590
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G+ + Q++++ K LG P ++ P
Sbjct: 591 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIW----PG 646
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFG-YAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P+ K F P K FG G DL+ L Y P RR S L H +F
Sbjct: 647 YSELPVVKKMTFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYF 705
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 127 bits (318), Expect = 3e-29
Identities = 93/316 (29%), Positives = 160/316 (50%), Gaps = 37/316 (11%)
Query: 32 RIGQGAFGTVVQ--AYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEY 89
++G+G + TV + + LT DN L ++ RE+ +L+ H N+V L
Sbjct: 122 KLGEGTYATVYKGKSKLT-DNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHD 180
Query: 90 FYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN--NLELPLKHVKLYAYQIARGMLYL 147
++ ++ + E L ++ +Y + N+ + + +VKL+ +Q+ RG+ Y
Sbjct: 181 I----------IHTEKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLLRGLAYC 229
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPELIV 204
H + HRD+KP N+L++ + G LK+ DFG A+ + P+ +Y + + +YR P++++
Sbjct: 230 HRQKVLHRDLKPQNLLIN-ERGELKLADFGLARA--KSIPTKTYSNEVVTLWYRPPDILL 286
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--FFSN-- 260
G T Y+T+ID+WG+GC+ EM G+ +F G QLH I ++LG P + SN
Sbjct: 287 GSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEE 346
Query: 261 -PSYNGPLF-SKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
+YN P + ++ L AP+ DG DLL +L +E R S + HPF
Sbjct: 347 FKTYNYPKYRAEALLSHAPR---------LDSDGADLLTKLLQFEGRNRISAEDAMKHPF 397
Query: 319 FDDLRNERYFFPSGSS 334
F L + P +S
Sbjct: 398 FLSLGERIHKLPDTTS 413
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 127 bits (318), Expect = 3e-29
Identities = 74/250 (29%), Positives = 130/250 (51%), Gaps = 16/250 (6%)
Query: 71 RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPL 130
RE++ LR +HPN+VKL+ I D + MEC + + K+ +L
Sbjct: 15 REVKSLRRMNHPNIVKLKEV---IRENDILYFVFEYMEC-------NLYQLMKDRQKLFA 64
Query: 131 K-HVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSI 189
+ +K + +Q+ +G+ Y+H G HRD+KP N+LV I+KI DFG A+++ S+ P
Sbjct: 65 EADIKNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKD--IIKIADFGLAREVNSSPPFT 122
Query: 190 SYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG 249
Y+ +R+YRAPE+++ YT+K+D+W +G ++ E+L + +F G ++++I ++G
Sbjct: 123 EYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIG 182
Query: 250 PPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRAS 309
P + N + P G P A D ++L+ + ++P R +
Sbjct: 183 TPTEETWLEGLNLANTINYQFPQLPGVP---LSSLMPSASEDAINLIERLCSWDPSSRPT 239
Query: 310 PRRILAHPFF 319
+L HPFF
Sbjct: 240 AAEVLQHPFF 249
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 126 bits (317), Expect = 4e-29
Identities = 90/301 (29%), Positives = 149/301 (48%), Gaps = 39/301 (12%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-----RELEILRIADHPNVVK 86
++G+G + TV + N+ A+K++ + E + RE+ +LR H NVV
Sbjct: 366 KLGEGTYATVFRGRSILTNKF----VALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVT 421
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN-NLELPLKHVKLYAYQIARGML 145
L I TD L + E + ++ +Y + N + + +++L+ YQ+ RG+
Sbjct: 422 LH----DIIHTDRLL------TLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLA 471
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
Y H + HRD+KP N+L+ + G LK+ DFG A+ + P+ +Y + + +YR P++
Sbjct: 472 YCHQRRVLHRDLKPQNLLITAK-GELKLADFGLARA--KSVPTKTYSNEVVTLWYRPPDV 528
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G T Y+T ID+WG+GC+L EM+ G+A+F G P QL I + LG P P
Sbjct: 529 LLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSP--------RPD 580
Query: 263 YNGPLFSKPLFEGAPKARFE-----KYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
+ + KP F + + G +LLM L YE + R S + HP
Sbjct: 581 RHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHP 640
Query: 318 F 318
F
Sbjct: 641 F 641
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 126 bits (317), Expect = 4e-29
Identities = 90/301 (29%), Positives = 149/301 (48%), Gaps = 39/301 (12%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-----RELEILRIADHPNVVK 86
++G+G + TV + N+ A+K++ + E + RE+ +LR H NVV
Sbjct: 243 KLGEGTYATVFRGRSILTNKF----VALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVT 298
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN-NLELPLKHVKLYAYQIARGML 145
L I TD L + E + ++ +Y + N + + +++L+ YQ+ RG+
Sbjct: 299 LH----DIIHTDRLL------TLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLA 348
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
Y H + HRD+KP N+L+ + G LK+ DFG A+ + P+ +Y + + +YR P++
Sbjct: 349 YCHQRRVLHRDLKPQNLLITAK-GELKLADFGLARA--KSVPTKTYSNEVVTLWYRPPDV 405
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G T Y+T ID+WG+GC+L EM+ G+A+F G P QL I + LG P P
Sbjct: 406 LLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSP--------RPD 457
Query: 263 YNGPLFSKPLFEGAPKARFE-----KYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
+ + KP F + + G +LLM L YE + R S + HP
Sbjct: 458 RHPTICEKPTFYPYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHP 517
Query: 318 F 318
F
Sbjct: 518 F 518
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 126 bits (316), Expect = 6e-29
Identities = 86/307 (28%), Positives = 154/307 (50%), Gaps = 34/307 (11%)
Query: 29 EYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQT----EYKSRELEILRIADHPNV 84
+++ +G G G V+ A + +K A+KK+ ++ RE++I+R DH N+
Sbjct: 22 DFQPLGFGVNGLVLSAVDSRACRK----VAVKKIALSDARSMKHALREIKIIRRLDHDNI 77
Query: 85 VKLEYFYTHISP--TD--HKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
VK+ Y + P TD +L++ + E ++ ++ R + L +H KL+ YQ+
Sbjct: 78 VKV---YEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT-LAEEHAKLFMYQL 133
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY----ICSRY 196
RG+ Y+H+ + HRD+KP+N+ + + +LKI DFG A+ ++ + Y + +++
Sbjct: 134 LRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKW 193
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH---EITKLLGPPDK 253
YR+P L++ YT ID+W GC+L EML G+ +F G L Q+ E ++ DK
Sbjct: 194 YRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDK 253
Query: 254 RFIFFSNPSYNGPLF--SKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPR 311
+ PS+ + +PL + P+ E +D L +L + P R +
Sbjct: 254 DELLRVMPSFVSSTWEVKRPLRKLLPEVNSE---------AIDFLEKILTFNPMDRLTAE 304
Query: 312 RILAHPF 318
L HP+
Sbjct: 305 MGLQHPY 311
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 126 bits (316), Expect = 6e-29
Identities = 97/328 (29%), Positives = 164/328 (49%), Gaps = 42/328 (12%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-----RELEIL 76
K E +K +++G+G + TV + ++ A+K++ + E + RE+ +L
Sbjct: 188 KMETYIK-LEKLGEGTYATVYKGR----SKLTENLVALKEIRLEHEEGAPCTAIREVSLL 242
Query: 77 RIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKH-VKL 135
+ H N+V L I TD L + E L ++ +Y + + H VKL
Sbjct: 243 KDLKHANIVTLH----DIVHTDKSL------TLVFEYLDKDLKQYMDDCGNIMSMHNVKL 292
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---I 192
+ YQI RG+ Y H + HRD+KP N+L++ + G LK+ DFG A+ + P+ +Y +
Sbjct: 293 FLYQILRGLAYCHRRKVLHRDLKPQNLLIN-EKGELKLADFGLARA--KSVPTKTYSNEV 349
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+ +YR P++++G ++Y T+ID+WG+GC+ EM G+ +F G +LH I +LLG P
Sbjct: 350 VTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPS 409
Query: 253 KRFI--FFSN---PSYNGPLFS-KPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPER 306
+ SN +YN P + +PL AP+ E G++L+ L YE ++
Sbjct: 410 QETWPGISSNEEFKNYNFPKYKPEPLINHAPRLDSE---------GIELIRKFLQYESKK 460
Query: 307 RASPRRILAHPFFDDLRNERYFFPSGSS 334
R S + H +F L + P S
Sbjct: 461 RVSAEEAMKHVYFRSLGPRIHALPESVS 488
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 126 bits (316), Expect = 6e-29
Identities = 95/308 (30%), Positives = 147/308 (46%), Gaps = 33/308 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY + AIKK+ QT K REL +++ +H N+
Sbjct: 30 KPIGSGAQGIVCAAYDAILERN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + ++ ME + L I +EL + + YQ+ G+
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 139
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 140 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +DIW +GC++GEM+ G +F G + Q +++ + LG P F+ P+
Sbjct: 199 GMG-YKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 265 GPLFSKPLFEGAPKARFEKYF------------GYAGPDGVDLLMSVLVYEPERRASPRR 312
+ ++P + G FEK F DLL +LV + +R S
Sbjct: 258 TYVENRPKYAG---YSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 313 ILAHPFFD 320
L HP+ +
Sbjct: 315 ALQHPYIN 322
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 126 bits (316), Expect = 6e-29
Identities = 95/308 (30%), Positives = 147/308 (46%), Gaps = 33/308 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY + AIKK+ QT K REL +++ +H N+
Sbjct: 30 KPIGSGAQGIVCAAYDAILERN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + ++ ME + L I +EL + + YQ+ G+
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 139
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 140 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +DIW +GC++GEM+ G +F G + Q +++ + LG P F+ P+
Sbjct: 199 GMG-YKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 265 GPLFSKPLFEGAPKARFEKYF------------GYAGPDGVDLLMSVLVYEPERRASPRR 312
+ ++P + G FEK F DLL +LV + +R S
Sbjct: 258 TYVENRPKYAG---YSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 313 ILAHPFFD 320
L HP+ +
Sbjct: 315 ALQHPYIN 322
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 125 bits (315), Expect = 7e-29
Identities = 88/296 (29%), Positives = 149/296 (49%), Gaps = 27/296 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+G+G++G V++ N+ AIKK + K RE+++L+ H N+V
Sbjct: 10 VGEGSYGMVMKCR----NKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L + K +L E + + +++ + L + V+ Y +QI G+ +
Sbjct: 66 L------LEVCKKKKRWYLVFEFVDHTILDDLELFPNG---LDYQVVQKYLFQIINGIGF 116
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICSRYYRAPELIVG 205
H+ I HRDIKP N+LV Q+G++K+CDFG A+ L + + Y+ +R+YRAPEL+VG
Sbjct: 117 CHSHNIIHRDIKPENILVS-QSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVG 175
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP--PDKRFIFFSNPSY 263
+Y +D+W +GC++ EM +G+ +F G + QL+ I LG P + +F NP +
Sbjct: 176 DVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVF 235
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
G L E + E+ + +DL L +P++R +L H FF
Sbjct: 236 AG----VRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 125 bits (315), Expect = 7e-29
Identities = 93/327 (28%), Positives = 159/327 (48%), Gaps = 26/327 (7%)
Query: 33 IGQGAFGTVVQ--AYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNV 84
+G G+FG V++ A ++++ AIKK+ P RE ++L++ H N+
Sbjct: 124 LGGGSFGNVIKTSAVCRDGLRRYV---AIKKMREPFFDPHHARRIFRETKLLQLMRHDNI 180
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN--NLELPLKHVKLYAYQIAR 142
+ YT D + ++ E L +IL+ +++ L +H+K YQI R
Sbjct: 181 ICALDIYTPDEENDFRDV-YVVTEFAGRSLY-QILKQQRDYGRRVLTDEHIKFIIYQIIR 238
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS-YICSRYYRAPE 201
+ Y+H+ I HRD+KP N+ + + ++ I DFG A+ LE S++ Y+ +R+YR+PE
Sbjct: 239 ALKYIHSANIIHRDLKPGNLALTDDSDLM-ILDFGLARSLEKKDTSLTQYVQTRWYRSPE 297
Query: 202 LIVG-CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIF-FS 259
+I YT D+W LGC+ E+L G+ +F G +P Q IT+L G PD+ +
Sbjct: 298 VIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIE 357
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGP--DGVDLLMSVLVYEPERRASPRRILAHP 317
N + + + + F F P D +DLL +LV +PE+R + + HP
Sbjct: 358 NDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHP 417
Query: 318 FFDDLRNERYFFPSGSSQPKHLPPLYD 344
+ + + P + H+ L D
Sbjct: 418 YLAE-----FSLPEDEPRADHIFDLDD 439
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 125 bits (315), Expect = 7e-29
Identities = 86/297 (28%), Positives = 149/297 (49%), Gaps = 23/297 (7%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEY-----KSRELEILRIADHP 82
K + +G G G+V +A N + A+KK+ + Y RE++ LR +HP
Sbjct: 13 KILEELGDGTCGSVYKAV----NLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHP 68
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
+++KL+ I ++L+ EC+ L + + K+ ++ + Q+ +
Sbjct: 69 HIIKLK----EIVREHNELF--FIFECMDHNLYHIM---KERERPFSEGEIRSFMSQMLQ 119
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
G+ ++H G HRD+KP N+LV ILKI DFG A+++ S P Y+ +R+YRAPE+
Sbjct: 120 GLAHMHKNGYFHRDLKPENLLVT--NNILKIADFGLAREVASMPPYTEYVSTRWYRAPEV 177
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++ + YT +D+W +G +L E+ +F G + QL++I +LG PD + F
Sbjct: 178 LLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPD--WTTFPEAK 235
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ S E P+ R A P+ +DL+ + ++P +R + L HPFF
Sbjct: 236 SISRIMSISHTE-FPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFF 291
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 125 bits (313), Expect = 1e-28
Identities = 94/308 (30%), Positives = 147/308 (47%), Gaps = 33/308 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY + AIKK+ QT K REL +++ +H N+
Sbjct: 30 KPIGSGAQGIVCAAYDAILERN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + ++ ME + L I +EL + + YQ+ G+
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 139
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 140 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +D+W +GC++GEM+ K +F G + Q +++ + LG P F+ P+
Sbjct: 199 GMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 265 GPLFSKPLFEGAPKARFEKYF------------GYAGPDGVDLLMSVLVYEPERRASPRR 312
+ ++P + G FEK F DLL +LV + +R S
Sbjct: 258 TYVENRPKYAG---YSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 313 ILAHPFFD 320
L HP+ +
Sbjct: 315 ALQHPYIN 322
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 125 bits (313), Expect = 1e-28
Identities = 94/308 (30%), Positives = 147/308 (47%), Gaps = 33/308 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA----QTEYKS--RELEILRIADHPNV 84
K IG GA G V AY + AIKK+ QT K REL +++ +H N+
Sbjct: 30 KPIGSGAQGIVCAAYDAILERN----VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI 85
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
+ L +T + ++ ME + L I +EL + + YQ+ G+
Sbjct: 86 IGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI------QMELDHERMSYLLYQMLCGI 139
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
+LH+ GI HRD+KPSN++V LKI DFG A+ ++ Y+ +RYYRAPE+I+
Sbjct: 140 KHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G Y +D+W +GC++GEM+ K +F G + Q +++ + LG P F+ P+
Sbjct: 199 GMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 265 GPLFSKPLFEGAPKARFEKYF------------GYAGPDGVDLLMSVLVYEPERRASPRR 312
+ ++P + G FEK F DLL +LV + +R S
Sbjct: 258 TYVENRPKYAG---YSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDE 314
Query: 313 ILAHPFFD 320
L HP+ +
Sbjct: 315 ALQHPYIN 322
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 125 bits (313), Expect = 1e-28
Identities = 88/296 (29%), Positives = 140/296 (46%), Gaps = 30/296 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+GQG +G V +A T Q AIKK+ + + RE+++L+ HP+++
Sbjct: 18 LGQGTYGVVFKATDTKTEQT----VAIKKIRLGKQREGVNITALREIKMLKELKHPHIIL 73
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L I HK HL E + L+ I + +N+ L +K Y +G+ Y
Sbjct: 74 L------IDAFPHKENLHLVFEFMETDLEAVI---RDSNIFLSPADIKSYLLMTFKGLAY 124
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICSRYYRAPELIVG 205
H + HRD+KP+N+L+ G LK+ DFG A+ S N+ + +R+YRAPEL+ G
Sbjct: 125 CHDKWVLHRDMKPNNLLIGVD-GQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFG 183
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP--DKRFIFFSNPSY 263
QY +D+W + C+ E+LL + QG+ + QL +I G P D+ P Y
Sbjct: 184 AKQYGAAVDVWAVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDY 243
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
++ P F D +DLL + Y+P+ R S ++ L H +F
Sbjct: 244 -------VEYQFVPAPSLRSLFPAVSDDALDLLSKMFTYDPKARISIKQALEHRYF 292
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 124 bits (312), Expect = 2e-28
Identities = 94/309 (30%), Positives = 158/309 (50%), Gaps = 32/309 (10%)
Query: 27 VKEYK---RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEY-----KSRELEILR- 77
+K YK +IG+G F V++ D +A K++ + E RE++ LR
Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNY----YACKQMKQRFESIEQVNNLREIQALRR 56
Query: 78 IADHPNVVKLEYFYTHISPTDHKLYQHLAMEC-LPEMLQNEILRYKKNNLELPLKHVKLY 136
+ HPN++ L H D K LA+ C L +M E++R ++ L K + Y
Sbjct: 57 LNPHPNILML-----HEVVFDRKSGS-LALICELMDMNIYELIRGRR--YPLSEKKIMHY 108
Query: 137 AYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRY 196
YQ+ + + ++H GI HRD+KP N+L+ + +LK+ DFGS + + S QP YI +R+
Sbjct: 109 MYQLCKSLDHIHRNGIFHRDVKPENILI--KQDVLKLGDFGSCRSVYSKQPYTEYISTRW 166
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI 256
YRAPE ++ YT K+D+W GCV E+ + +F G L Q+ +I ++G P ++ +
Sbjct: 167 YRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKIL 226
Query: 257 --FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
F + + N F P +G+ P + LL +++ Y+P+ R + + L
Sbjct: 227 TKFKQSRAMN---FDFPFKKGSGIPLLTTNL---SPQCLSLLHAMVAYDPDERIAAHQAL 280
Query: 315 AHPFFDDLR 323
HP+F + R
Sbjct: 281 QHPYFQEQR 289
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 124 bits (312), Expect = 2e-28
Identities = 93/304 (30%), Positives = 144/304 (46%), Gaps = 28/304 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNVV 85
+ G+G++G V + Q A+KK P + RE+ +L+ HPN+V
Sbjct: 9 KTGEGSYGVVFKCRNKTSGQV----VAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLV 64
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAY----QIA 141
L I K HL E L NE+ R N ++ +L + ++A
Sbjct: 65 NL------IEVFRRKRKMHLVFEYCDHTLLNELER-NPNGMDSDSIVGRLRSVADRSRLA 117
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPE 201
+ L HRDIKP N+L+ Q GI+KICDFG A+ L Y+ +R+YRAPE
Sbjct: 118 PKNNQIMILQCIHRDIKPENILITKQ-GIIKICDFGFAQILIPGDAYTDYVATRWYRAPE 176
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP--PDKRFIFFS 259
L+VG TQY + +DIW +GCV E+L G+ ++ G + QL+ I + LG P + IF S
Sbjct: 177 LLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKS 236
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
N ++G +P E+ F P ++ + L P+ R + ++L +F
Sbjct: 237 NGFFHGISIPEP----EDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYF 292
Query: 320 DDLR 323
D +
Sbjct: 293 DSFQ 296
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 124 bits (312), Expect = 2e-28
Identities = 93/314 (29%), Positives = 148/314 (46%), Gaps = 38/314 (12%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNV 84
+ IG GAFG V +A T NQK AIKKV P RE+ +LR +HPN+
Sbjct: 86 QNIGSGAFGIVCEAVETSSNQK----VAIKKVAHASATPTLARRTLREIRVLRYINHPNI 141
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLK--HVKLYAYQIAR 142
V L + P ++ + +++QN + N E PL+ ++ + Q+ R
Sbjct: 142 VPLRDIFRTKGPLGIDVF------LVMDLMQNNLHHIIYGN-EDPLEEHYINAFLGQLLR 194
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS----------ISYI 192
G+ YLHA I HRD+KPSN+LV+ Q G L+I DFG AK +++ ++
Sbjct: 195 GLEYLHAACIAHRDLKPSNLLVN-QDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHV 253
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+ YRAPEL+ +++T +D+W +GC+ GEM++ + G Q+ + +LG P
Sbjct: 254 ATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPP 313
Query: 253 KRFIFFSNPSYNGPLFS----KPLFEGAP----KARFEKYFGYAGPDGVDLLMSVLVYEP 304
+ I L K E KAR + D +D + + Y+
Sbjct: 314 QEVINEVRCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVKQLFQYDA 373
Query: 305 ERRASPRRILAHPF 318
++R + + L HP+
Sbjct: 374 QKRINIQDALLHPY 387
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 124 bits (311), Expect = 2e-28
Identities = 85/300 (28%), Positives = 152/300 (50%), Gaps = 34/300 (11%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTE-----YKSRELEILRIADHPNVV 85
+++G G +G+V+ + AIKK+ + RE++ L+ +H NVV
Sbjct: 8 RQLGDGTYGSVLLGRSIESGEL----IAIKKMKRKFYSWEECMNQREVKSLKKLNHANVV 63
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
KL+ I DH + E + E L I K+ N P ++ YQI +G+
Sbjct: 64 KLKEV---IRENDHLYF---IFEYMKENLYQLI---KERNKLFPESAIRNIMYQILQGLA 114
Query: 146 YLHALGICHRDIKPSNVL-VDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
++H LG HRD+KP N+L + P+ ++KI DFG A+++ S P Y+ +R+YRAPE+++
Sbjct: 115 FIHKLGFFHRDLKPENLLCMGPE--LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLL 172
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR-----FIFFS 259
T Y++ ID+W +GC++ E+ + +F G + + +I ++LG P K + S
Sbjct: 173 RSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSS 232
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
++ P + P + A + V LL +L ++P++R + + L +P+F
Sbjct: 233 AMNFRWP-------QCVPN-NLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 87 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 142
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 143 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 195
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 196 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 252
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 253 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 308
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 309 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 367
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 419 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 474
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 475 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 527
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 528 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 584
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 585 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 640
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 641 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 699
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 428 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 483
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 484 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 536
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 537 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 593
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 649
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 650 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 109 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 164
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 165 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 217
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 218 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 274
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 275 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 330
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 331 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 389
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 213 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 268
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 269 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 321
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 322 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 378
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 379 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 434
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 435 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 493
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 396 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 451
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 452 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 504
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 505 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 561
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 562 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 617
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 618 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 676
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 385 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 440
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 441 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 493
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 494 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 550
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 551 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 606
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 607 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 665
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 174 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 229
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 230 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 282
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 283 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 339
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 340 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 395
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 396 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 454
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 430 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 485
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 486 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 538
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 539 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 595
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 596 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 651
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 652 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 710
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 124 bits (311), Expect = 2e-28
Identities = 95/299 (31%), Positives = 149/299 (49%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A ++K A+K++ + E + RE+ + A HPN+V
Sbjct: 443 RIEEGTYGVVYRA----KDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIV 498
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K+Y + M + L++ + K+ L VK Q+ RG+
Sbjct: 499 TVREIV--VGSNMDKIY--IVMNYVEHDLKSLMETMKQPFLP---GEVKTLMIQLLRGVK 551
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
+LH I HRD+K SN+L+ GILK+ DFG A+ E P +Y + + +YRAPEL
Sbjct: 552 HLHDNWILHRDLKTSNLLLS-HAGILKVGDFGLAR--EYGSPLKAYTPVVVTLWYRAPEL 608
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +Y+T +D+W +GC+ GE+L K +F G + Q++++ K LG P ++ P
Sbjct: 609 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIW----PG 664
Query: 263 YNG-PLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFF 319
Y+ P K F P K FG D G DL+ L Y P RR S L H +F
Sbjct: 665 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 723
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 124 bits (311), Expect = 2e-28
Identities = 94/326 (28%), Positives = 154/326 (46%), Gaps = 36/326 (11%)
Query: 26 LVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEY-----KSRELEILRIAD 80
L K ++G+G++ TV + D A+K++ Q + RE +LR
Sbjct: 107 LYKRIDKLGEGSYATVYKCESKLDGSI----VALKEIKLQFQEGLPFTAIREASLLRNLR 162
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLE-LPLKHVKLYAYQ 139
H N+V L + YQH + + E ++ ++ +Y + N+ L +KL +Q
Sbjct: 163 HANIVSLHDIF----------YQHHQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLFQ 212
Query: 140 IARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRY 196
+ RG+ + H I HRD+KP N+L+D + G+LK+ DFG A+ + PS +Y + + +
Sbjct: 213 LLRGLDFCHRKKILHRDLKPQNLLLD-EDGVLKLADFGLARA--KSVPSRTYSHEVVTLW 269
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQG----HQPLL--QLHEITKLLGP 250
YR P++++G T Y+T +D+WG+GC+ E+ G A+F G H P QL I + G
Sbjct: 270 YRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGT 329
Query: 251 PDKRF--IFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRA 308
PD++ + P Y LF P + F G +LL +L PE R
Sbjct: 330 PDEKKWPEVKTLPGYTPELF--PRYRELSFIAVNPMFTKILKTGQELLGMLLQLRPESRV 387
Query: 309 SPRRILAHPFFDDLRNERYFFPSGSS 334
S + HP+F E + S
Sbjct: 388 SAASAMLHPYFASFPREVHLLAPSQS 413
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 123 bits (308), Expect = 5e-28
Identities = 89/304 (29%), Positives = 151/304 (49%), Gaps = 31/304 (10%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILR-IADHPNV 84
+IG+G+ + + T N++ AI+K+P K REL++LR + HPN+
Sbjct: 28 KIGRGSHSLICSSTYTESNEET--HVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNI 85
Query: 85 VKLE----YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
V L FY + + LY+ L MEC ++ + ++ L H + + YQI
Sbjct: 86 VWLFDTDIVFYPNGALNGVYLYEEL-MEC-------DLSQIIRSEQRLEDAHFQSFIYQI 137
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS-----YICSR 195
+ Y+H+ + H D+KP N+LV+ LKIC+FG + N YI S
Sbjct: 138 LCALKYIHSANVLHCDLKPKNLLVNSDCQ-LKICNFGLSCSYSENHKVNDGFIKGYITSI 196
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPDKR 254
+Y+APE+++ + T +DIW GC+L E+L K +F+G + L+ I ++LG PP++
Sbjct: 197 WYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEET 256
Query: 255 FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRIL 314
++ +F F P FE A P+ ++LL +L ++P++R + L
Sbjct: 257 LQEIASQKVYNYIFQ---FGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDAL 313
Query: 315 AHPF 318
HP+
Sbjct: 314 EHPY 317
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 123 bits (308), Expect = 5e-28
Identities = 82/306 (26%), Positives = 154/306 (49%), Gaps = 27/306 (8%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ ++IG+G +G V + Q A+KK+ +++ + RE+ +L+ H
Sbjct: 5 EKIEKIGEGTYGVVYKGRNRLTGQI----VAMKKIRLESDDEGVPSTAIREISLLKELKH 60
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
N+V LE + + +++ L+M+ M + ++ ++ L V+ Y YQI
Sbjct: 61 ENIVCLEDVLMEENRI-YLIFEFLSMDLKKYMDSLPVDKHMESEL------VRSYLYQIT 113
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRAP 200
+L+ H + HRD+KP N+L+D ++G++K+ DFG + ++ I + +YRAP
Sbjct: 114 SAILFCHRRRVLHRDLKPQNLLID-KSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAP 172
Query: 201 ELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--FF 258
E+++G +Y+ +DIW +GC+ EM K +FQG + QL + ++L P +
Sbjct: 173 EVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVT 232
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
S P Y K F + +G+DL+ +L+Y+P R S + IL HP+
Sbjct: 233 SLPDY------KNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPY 286
Query: 319 FDDLRN 324
F+ ++
Sbjct: 287 FNGFQS 292
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 122 bits (307), Expect = 6e-28
Identities = 89/299 (29%), Positives = 147/299 (48%), Gaps = 29/299 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS--------RELEILRIADHPN 83
RI G+FG V + DN+ FA+K++ Y + RE+ IL+ H N
Sbjct: 31 RISSGSFGNVYRVRRKTDNRV----FALKRMNPSMCYDTNGFSILYIREVMILKHIRHRN 86
Query: 84 VVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
++++E D + MEC L++ I K + +K + Q+ +G
Sbjct: 87 IMEIEEVVEGCEINDF----FIVMECCDTDLRSVIHSVGK----IGMKAARFLTCQMLKG 138
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
+ +LH GI HRD+KPSN+L+ + G L+I DFG A+ +ES ++ + + +YR E++
Sbjct: 139 LKFLHGAGIVHRDLKPSNILL-MRDGGLRIADFGLARAIESQMTNL--VVTLWYRPIEIL 195
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG-PPDKRFIFFSNPS 262
+G Y ID+W +GCV+GEML G+ + G + QL I +LLG P D F P
Sbjct: 196 LGSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADFEGLDLPH 255
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDD 321
+ + FE + + FE Y G + + ++L ++P +R + + L F D
Sbjct: 256 FKN-IRRPSTFEASFEGDFECY----GEEAASFVRNLLSFDPRKRCTASQGLCSGFVAD 309
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 122 bits (307), Expect = 6e-28
Identities = 86/297 (28%), Positives = 143/297 (47%), Gaps = 32/297 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVVK 86
+G+G +G V +A T + A+KK+ + + RE+++L+ +HP++V+
Sbjct: 19 LGEGTYGVVYKATDTKTGKT----VAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVE 74
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L + H D L HL E + L+ I + N+ L +K Y +G+ Y
Sbjct: 75 LIDAFPH----DGSL--HLVFEYMQTDLEAVI---RDRNIFLSPGDIKSYMLMTLKGLAY 125
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICSRYYRAPELIVG 205
H + HRD+KP+N+L+ + G+LK+ DFG A+ S N+ + + +YRAPEL+ G
Sbjct: 126 CHKKWVLHRDMKPNNLLIG-ENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFG 184
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNG 265
QY +D+W GC+ E+LL + G + QL +I + G P PS
Sbjct: 185 SRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTP--------VPSQWS 236
Query: 266 PLFSKP---LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ P F P F A D +DLL + +Y+P +R + ++ L H +F
Sbjct: 237 DMIYLPDYMEFSYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYF 293
>SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases
Length = 690
Score = 122 bits (306), Expect = 8e-28
Identities = 101/354 (28%), Positives = 161/354 (44%), Gaps = 67/354 (18%)
Query: 12 HDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSR 71
+ V+ N R +V+ +G G FG V+Q Y +Q AIK A +Y+
Sbjct: 350 YKVVPNSKFANRYTVVR---LLGHGTFGKVIQCY----DQSTGRHCAIKVTRAIPKYREA 402
Query: 72 ELEILRIADHPNVVKLEYFYTHISPTDHK-------LYQHLAMECL-PEMLQNEILRYKK 123
L LR+ H PT+ + + C+ ++ + + K
Sbjct: 403 SLIELRVLQT---------IAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLK 453
Query: 124 NN--LELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTG------------ 169
NN + PLKH+++ + Q+ + + +LH+LG+ H D+KP NVL+
Sbjct: 454 NNNYIPFPLKHIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQ 513
Query: 170 -ILKIC-----DFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLG 223
+L C DFGSA + S+ + +R+YRAPE+I+G ++ D+W +GC+L
Sbjct: 514 KVLNSCEIRLIDFGSATFEDEYHSSV--VSTRHYRAPEIILG-LGWSYPCDVWSIGCILV 570
Query: 224 EMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNGPLFSK-------PLFEGA 276
E+ G+A+FQ H+ L + K+LGP D+ I S S F K PL
Sbjct: 571 ELFTGQALFQTHEDSEHLCMMEKILGPFDRNMI--SRSSRTSQRFFKSDGKVRYPLSNTP 628
Query: 277 PKA--------RFEKYFGYAGPDG---VDLLMSVLVYEPERRASPRRILAHPFF 319
K+ E+ F + P+ +DLL V VY+P+RR + + L HPFF
Sbjct: 629 KKSINYLQSLQTLEQIFAVSSPEVALLLDLLKKVFVYDPKRRITAKEALWHPFF 682
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 122 bits (306), Expect = 8e-28
Identities = 107/332 (32%), Positives = 162/332 (48%), Gaps = 38/332 (11%)
Query: 16 SNKSNVKREMLVKEYK---RIGQGAFGTVVQAYL-TPDNQKWLGPFAIKKVPAQTEYKS- 70
SN ++ K E L ++Y +IG+G +G V A TP + P AIKK +
Sbjct: 12 SNSTSEKPEWL-QQYNLVGKIGEGTYGLVFLARTKTPPKR----PIAIKKFKQSKDGDGV 66
Query: 71 -----RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNN 125
RE+ +LR H NVVKL HI+ D LY LA + L EI+R+ ++
Sbjct: 67 SPTAIREIMLLREISHENVVKL--VNVHINFADMSLY--LAFDYAEYDLY-EIIRHHRDK 121
Query: 126 L--ELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLV---DPQTGILKICDFGSAK 180
+ L VK +Q+ G+ YLH+ I HRD+KPSN+LV + GI+KI DFG A+
Sbjct: 122 VGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLAR 181
Query: 181 KLESNQPSIS---YICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQ- 236
++ +S + + +YRAPEL++G YT+ +D+W +GC+ E+L K +FQG +
Sbjct: 182 IYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGAEA 241
Query: 237 -------PLLQLHEITKLLGPP--DKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGY 287
L QL +I K+LG P DK + P + + +
Sbjct: 242 KSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNVVHLN 301
Query: 288 AGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
DLL +L Y+P +R + + L H +F
Sbjct: 302 QKSPAYDLLSKMLEYDPLKRITASQALEHEYF 333
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 122 bits (306), Expect = 8e-28
Identities = 91/285 (31%), Positives = 140/285 (48%), Gaps = 17/285 (5%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKL 87
K ++IG+G G V +A N++ AIKKV + ++ + L LR + K
Sbjct: 10 KMLEKIGEGVHGCVFKAIDLQRNKE----VAIKKVALKNKFGNIALNTLREIKTLQLCKS 65
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
EY I L +E P+ L N R K L + V+ +A+Q+ +G+ YL
Sbjct: 66 EYILDIIDIYPDLTGLSLVLEYQPDTLYN---RLKSEVNPLSRQQVRKFAHQMFKGIAYL 122
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPELIV 204
H G+ HRDIKP+N+L+ T +LKI DFG A+ S Y + +R+YRAPE++
Sbjct: 123 HEAGLMHRDIKPANLLIS-DTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILF 181
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN 264
G +Y T +D+W GCV+ EML G +F G + QL I + LG P P
Sbjct: 182 GSQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLN----QWPELT 237
Query: 265 G-PLFSKPLFEGAPKARFEKYF-GYAGPDGVDLLMSVLVYEPERR 307
P +SK F + ++ F ++L+ +++VY P+ R
Sbjct: 238 SLPDYSKIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNR 282
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 122 bits (305), Expect = 1e-27
Identities = 96/304 (31%), Positives = 146/304 (47%), Gaps = 28/304 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQ-----KWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKL 87
+ GA GTVV A Q K PF + + A+ Y RE +L HPN+++L
Sbjct: 44 LNAGAQGTVVMADDLVTTQRVAIKKMQQPF-VMTMSAKRAY--REFILLTTIKHPNIIRL 100
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
+T + +L ME + L I R L L K + + YQ + +L
Sbjct: 101 LNAFTPDTSLSTFREVYLVMELMTHNLHEVIHR-----LRLDHKTLSFFVYQSLCAIKHL 155
Query: 148 HALGICHRDIKPSNVLVDPQTGILKICDFGSAKK--LESNQPSISYICSRYYRAPELIVG 205
H G+ HRD+KPSN++V+ + +LK+ DFG A+K ++++ Y+ +RYYRAPE+I+G
Sbjct: 156 HNSGVIHRDLKPSNIVVNDRC-VLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILG 214
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--------- 256
Y+ K+DIW +GC+ EM+ +F G + Q +I +LG PD FI
Sbjct: 215 LP-YSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAM 273
Query: 257 -FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV-DLLMSVLVYEPERRASPRRIL 314
S P + FS+ + + E + P DLL ++L PE R S L
Sbjct: 274 YVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVEDAL 333
Query: 315 AHPF 318
HP+
Sbjct: 334 NHPY 337
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 121 bits (303), Expect = 2e-27
Identities = 95/359 (26%), Positives = 160/359 (44%), Gaps = 66/359 (18%)
Query: 12 HDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDN-----QKWLGPFAIKKVPAQT 66
H+V NK+ K +G+GA+G V A P +K+ PF + A+
Sbjct: 34 HEVELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQ-STIHAKR 92
Query: 67 EYKSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNL 126
Y REL++LR H NV+++ +T + + LQN I++ ++
Sbjct: 93 TY--RELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQN-IMKIQR--- 146
Query: 127 ELPLKHVKLYAYQIARGM-----------------------------LYLHALGICHRDI 157
L + ++L YQ+ RG+ LY+H+ GI HRD+
Sbjct: 147 -LTDEQIQLLIYQVLRGLKYMSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDL 205
Query: 158 KPSNVLVDPQTGI----------------LKICDFGSAKKLESNQPSISYICSRYYRAPE 201
KPSN+ V+ + + KI DFG A+ ++ Y+ +R+YRAPE
Sbjct: 206 KPSNIAVNERCEVKVFLSFSQLSFLILSFFKILDFGLARAQDAEMTG--YVATRWYRAPE 263
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF--IFFS 259
+++ YT +D+W +GC+L E++ G+ +F G + QL +I ++G P + F S
Sbjct: 264 IMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQS 323
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
+ N P+ + F F A P ++LL +L+ +P+RR S L H +
Sbjct: 324 EEARNYIKNRSPII----RQDFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDY 378
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 120 bits (302), Expect = 2e-27
Identities = 84/300 (28%), Positives = 151/300 (50%), Gaps = 34/300 (11%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTE-----YKSRELEILRIADHPNVV 85
+++G G +G+V+ + AIKK+ + RE++ L+ +H NVV
Sbjct: 8 RQLGDGTYGSVLLGRSIESGEL----IAIKKMKRKFYSWEECMNLREVKSLKKLNHANVV 63
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
KL+ I DH + E + E L I K+ N P ++ YQI +G+
Sbjct: 64 KLKEV---IRENDHLYF---IFEYMKENLYQLI---KERNKLFPESAIRNIMYQILQGLA 114
Query: 146 YLHALGICHRDIKPSNVL-VDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
++H G HRD+KP N+L + P+ ++KI DFG A+++ S P Y+ +R+YRAPE+++
Sbjct: 115 FIHKHGFFHRDLKPENLLCMGPE--LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLL 172
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR-----FIFFS 259
T Y++ ID+W +GC++ E+ + +F G + + +I ++LG P K + S
Sbjct: 173 RSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSS 232
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
++ P + P + A + V LL +L ++P++R + + L +P+F
Sbjct: 233 AMNFRWP-------QCVPN-NLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 120 bits (301), Expect = 3e-27
Identities = 89/322 (27%), Positives = 154/322 (47%), Gaps = 38/322 (11%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKSRELEILR-IADHPNVVKL 87
+++G+G + V +A +N+K + K+ P + + RE++IL + PN++ L
Sbjct: 43 RKLGRGKYSEVFEAINITNNEK-----VVVKILKPVKKKKIKREIKILENLRGGPNIITL 97
Query: 88 -EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+ +S T +++H+ ++ Q L ++ Y Y+I + + Y
Sbjct: 98 ADIVKDPVSRTPALVFEHVNNTDFKQLYQT-----------LTDYDIRFYMYEILKALDY 146
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
H++GI HRD+KP NV++D + L++ D+G A+ Q + SRY++ PEL+V
Sbjct: 147 CHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 206
Query: 207 TQYTTKIDIWGLGCVLGEMLLGK-AVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYN- 264
Y +D+W LGC+L M+ K F GH QL I K+LG D ++ YN
Sbjct: 207 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTED---LYDYIDKYNI 263
Query: 265 --GPLFSKPLFEGAPKARFEKYF-----GYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
P F+ L + K R+E++ P+ +D L +L Y+ + R + R + HP
Sbjct: 264 ELDPRFNDILGRHSRK-RWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP 322
Query: 318 FF-----DDLRNERYFFPSGSS 334
+F D R P GS+
Sbjct: 323 YFYTVVKDQARMGSSSMPGGST 344
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 120 bits (301), Expect = 3e-27
Identities = 88/312 (28%), Positives = 154/312 (49%), Gaps = 43/312 (13%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ ++IG+G +G V +A N+ A+KK+ + E + RE+ +L+ H
Sbjct: 6 QKLEKIGEGTYGVVYKARERNTNRV----VALKKIRLENENEGIPATTIREILLLKNLKH 61
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
+V+L + + ++K+Y L E + L+ + R + V+ + Q+
Sbjct: 62 STIVEL----SDVIYNNNKMY--LVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLL 115
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYR 198
M Y H+ I HRD+KP N+LVDP+ I K+ DFG + + P +Y + + +YR
Sbjct: 116 TAMEYCHSRNIFHRDLKPQNILVDPKENI-KLADFGLGRA--AGIPLRTYTTEVVTLWYR 172
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP-DKRFIF 257
PEL++GC Y +D+W C++ E++L + F G + QL I K+LG P + R+
Sbjct: 173 PPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSN 232
Query: 258 FSN-PSYN------GPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASP 310
N P+Y P+ K +F G PD VDL+ +L Y+P+ R +
Sbjct: 233 VENFPNYKVEFPVWDPVDLKTIFRG-------------DPDFVDLISKMLEYDPKMRMTA 279
Query: 311 RRILAHPFFDDL 322
+ L+H +F+ +
Sbjct: 280 KNGLSHKYFEGM 291
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 120 bits (301), Expect = 3e-27
Identities = 93/321 (28%), Positives = 158/321 (48%), Gaps = 37/321 (11%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILR-IA 79
++ +++G+G +G V +A +K G A+KK + + + RE+ +L+ ++
Sbjct: 5 EKLEKVGEGTYGKVYKAM-----EKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS 59
Query: 80 DHPNVVKL---EYFY---THISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKH- 132
VV+L E+ + T T LY L E L L+ I Y+K PL+
Sbjct: 60 TSIYVVRLLCVEHVHQPSTKSQSTKSNLY--LVFEYLDTDLKKFIDSYRKGPNPKPLEPF 117
Query: 133 -VKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY 191
++ +Q+ +G+ + H+ G+ HRD+KP N+L+ +LKI D G + S ++
Sbjct: 118 LIQKLMFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTH 177
Query: 192 -ICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP 250
I + +YRAPE+++G T Y+T +D+W +GC+ EM+ +A+F G QL I +LLG
Sbjct: 178 EIVTLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGT 237
Query: 251 PDKRFIFFSNPSYNGPLFSK----PLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPER 306
P ++ + + ++ K L P P GVDLL +L Y P
Sbjct: 238 PTEQQWPGVSTLRDWHVYPKWEPQDLTLAVPS---------LSPQGVDLLTKMLKYNPAE 288
Query: 307 RASPRRILAHPFFDDLRNERY 327
R S + L HP+FD L ++
Sbjct: 289 RISAKTALDHPYFDSLDKSQF 309
>CE01612 [G] KOG0658 Glycogen synthase kinase-3
Length = 410
Score = 120 bits (300), Expect = 4e-27
Identities = 74/232 (31%), Positives = 123/232 (52%), Gaps = 16/232 (6%)
Query: 27 VKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSR------ELEILRIAD 80
+ +K G G F V + +K + A+K V + TE + E++IL
Sbjct: 27 ISAHKLCGSGRFSNVYCGQMISPIEKEV---AVKNVWSDTETRHLATSEYPEIQILSKLF 83
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
HP + L YFY+ + + K+ L ++ LP+ ++ R + ++ + KLY +Q+
Sbjct: 84 HPAISNLLYFYSRNA--NDKVINCLVLDYLPQ----DLARLRDQGVKFDVLDAKLYTFQL 137
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS-YICSRYYRA 199
+ +L + I H DIKP NV++D G LK+ DFG+A++LE+N+ + S Y +R+YR
Sbjct: 138 FCAISHLTSKNIVHMDIKPQNVVMDRMAGRLKLADFGNARRLETNEKTGSAYQVTRFYRP 197
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP 251
PEL+ GC ++T IDIW CV E+ + +F+G Q+ IT + G P
Sbjct: 198 PELLFGCEKFTASIDIWSATCVAFELFANRVLFKGKDTKDQIVLITGVFGYP 249
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 119 bits (299), Expect = 5e-27
Identities = 89/335 (26%), Positives = 160/335 (47%), Gaps = 46/335 (13%)
Query: 29 EYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV----PAQTEYKSRELEILRIADHPNV 84
+ K +G G G V A +++ AIKK+ P ++ RE++I+R DH N+
Sbjct: 22 DLKPLGCGGNGLVFSAVDNDCDKR----VAIKKIVLTDPQSVKHALREIKIIRRLDHDNI 77
Query: 85 VKLEYFYTHISPTDHKLYQHL-------AMECLPEMLQNEILRYKKNNLELPLKHVKLYA 137
VK+ + + P+ +L + ++ + E ++ ++ + L +H +L+
Sbjct: 78 VKV---FEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLE-EHARLFM 133
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY----IC 193
YQ+ RG+ Y+H+ + HRD+KP+N+ ++ + +LKI DFG A+ ++ + + +
Sbjct: 134 YQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGLV 193
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLH---EITKLLGP 250
+++YR+P L++ YT ID+W GC+ EML GK +F G L Q+ E ++
Sbjct: 194 TKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHE 253
Query: 251 PDKRFIFFSNPSYNGPLFS---KPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERR 307
D++ + P Y + KPL + P E +D L +L + P R
Sbjct: 254 EDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISRE---------ALDFLEQILTFSPMDR 304
Query: 308 ASPRRILAHPFFDDLRNERYFFPSG---SSQPKHL 339
+ L+HP+ Y FP SS P H+
Sbjct: 305 LTAEEALSHPYM-----SIYSFPMDEPISSHPFHI 334
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 119 bits (299), Expect = 5e-27
Identities = 79/239 (33%), Positives = 123/239 (51%), Gaps = 18/239 (7%)
Query: 114 LQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKI 173
+++++ + ++ L L+HV+ + YQ+ RG+ Y+H+ + HRD+KPSN+LV+ LKI
Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCE-LKI 59
Query: 174 CDFGSAKKL-----ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLG 228
DFG A+ L E Y+ +R+YRAPEL++ +YT ID+W +GC+ GEML
Sbjct: 60 GDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLAR 119
Query: 229 KAVFQGHQPLLQLHEITKLLGPPDKRFI-FFSNPSYNGPLFSKPLFEGAPKARFEKYFGY 287
+ +F G + QL I +LG P I + S P + P +E +
Sbjct: 120 RQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVP---WETVYPG 176
Query: 288 AGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFS 346
A + LL +L +EP R S L HPF +Y P +P PP +DF+
Sbjct: 177 ADRQALSLLGRMLRFEPSARISAAAALRHPFL-----AKYHDP--DDEPDCAPP-FDFA 227
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 119 bits (297), Expect = 9e-27
Identities = 91/308 (29%), Positives = 151/308 (48%), Gaps = 29/308 (9%)
Query: 23 REMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYK------SRELEIL 76
RE ++ ++IG G F V +A N+ A+K++ +RE+ IL
Sbjct: 99 RESHFEKQEQIGGGTFSKVFKARDLLRNKT----VALKRIRFDINNSESIKCIAREIIIL 154
Query: 77 RIADHPNVVKLE--YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVK 134
R DHPNV+KLE H S T + +++++ + L + +L + VK
Sbjct: 155 RKLDHPNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLG---LSSLL-----GVHFSEPQVK 206
Query: 135 LYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQ--PSISYI 192
Y Q+ RG+ + H + HRD+K SN+L++ G+LKI DFG A + + P +++
Sbjct: 207 CYMRQLLRGLDHCHTNHVLHRDMKSSNLLINGD-GVLKIADFGLATFFDPHNSVPLTTHV 265
Query: 193 CSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPD 252
+ +YR PEL++G + Y +D+W GCV+GE+ GK + G QLH+I KL G P
Sbjct: 266 ATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPS 325
Query: 253 KRFIFFSNPSYNGPLFSKPLFE-GAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPR 311
+ + PL +P++ G+ A K F + LL ++L +P+ R +
Sbjct: 326 DDYWTKLKLQLSTPL--RPIYPYGSHIAETFKQF---PASVISLLETLLSIDPDFRGTAA 380
Query: 312 RILAHPFF 319
L +F
Sbjct: 381 SALKSKYF 388
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 118 bits (296), Expect = 1e-26
Identities = 99/335 (29%), Positives = 157/335 (46%), Gaps = 43/335 (12%)
Query: 30 YKRIG---QGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-------------REL 73
YK IG G +G V +A + N K L FAIKK A+++ S RE+
Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRL--FAIKKFKAESKQVSSNAQQTGVSQSAIREM 62
Query: 74 EILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHV 133
+ R H N+V L T ++++ + +LQ + ++P +
Sbjct: 63 MLCREIQHENIVSLVQVLLK-DGTISMVFEYAEHD----LLQIIHFHSRSRTRQIPPSIL 117
Query: 134 KLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN----QPSI 189
K +QI G+ YLH I HRD+KP+N+++ TG +KI D G + + S
Sbjct: 118 KSILWQIINGVAYLHENWIMHRDLKPANIMITA-TGKVKIGDLGLGRLIRDPILPFYSSD 176
Query: 190 SYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL---------- 239
+ + +YRAPEL++G YT ID+W +GC+ GEML +F+G + +
Sbjct: 177 RVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQS 236
Query: 240 -QLHEITKLLG-PPDKRFIFFSN-PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLL 296
Q+ I +LLG P ++R+ N P Y + + ++ + P G+DLL
Sbjct: 237 TQMLRIMELLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNLLPQWYQTVKNRDPQGLDLL 296
Query: 297 MSVLVYEPERRASPRRILAHPFF--DDLRNERYFF 329
M +L Y+P+ R + ++ L H FF D L RY F
Sbjct: 297 MKMLQYDPKSRITAKQALEHVFFTSDKLWTTRYVF 331
>Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 589
Score = 118 bits (296), Expect = 1e-26
Identities = 106/331 (32%), Positives = 159/331 (48%), Gaps = 53/331 (16%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
IG+G+FG VV+AY Q+ + IK A EL +L + + + +++Y+
Sbjct: 117 IGKGSFGQVVKAY-DHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDT-EMKYYIV 174
Query: 93 HISPTDHKLYQH---LAMECLP----EMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
H+ H ++++ L E L ++L+N R NL L A Q+ +L
Sbjct: 175 HLKR--HFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKL------AQQLCTALL 226
Query: 146 YLHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE+
Sbjct: 227 FLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEV 284
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G T Y ID+W LGC+L EM G+ +F G + Q++ I ++LG P
Sbjct: 285 LLG-TPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIP----------- 332
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDG----------VDLLMSVLVYEPERRASPRR 312
+ + APKAR KYF G DL++ +L YEP R SP
Sbjct: 333 ------PAAMLDQAPKAR--KYFERLPGGGWTLRRTKELRKDLVLRMLEYEPAARISPLG 384
Query: 313 ILAHPFFDDLRNE-RYFFPSGSSQPKHLPPL 342
L H FF +E P+GSS PL
Sbjct: 385 ALQHGFFRRTADEATNTGPAGSSASTSPAPL 415
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 118 bits (295), Expect = 2e-26
Identities = 88/317 (27%), Positives = 150/317 (46%), Gaps = 45/317 (14%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
+++G+G FG V ++ D + +A+K++ TE + RE++IL+ H N+
Sbjct: 40 EKLGEGTFGEVYKSQRRKDGKV----YALKRILMHTEKEGFPITAIREIKILKSIKHENI 95
Query: 85 VKLEYFYTHISPTDHKLYQHLAMEC------LPEMLQNEILRYKKNNLELPLKHVKLYAY 138
+ L + H+ + M L +L+N +++ + +K Y
Sbjct: 96 IPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTE-------PQIKCYMK 148
Query: 139 QIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLE-----SNQPSI---- 189
Q+ G YLH I HRD+K +N+L+D GILKI DFG A+ + + P +
Sbjct: 149 QLFAGTKYLHDQLILHRDLKAANLLIDNH-GILKIADFGLARVITEESYANKNPGLPPPN 207
Query: 190 -----SYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEI 244
+ +R+YR+PEL++G +YTT ID+W +GC++ EM G+ + QG L QL +I
Sbjct: 208 RREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKI 267
Query: 245 TKLLGPPDKRFI--FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVY 302
+L G P + + + P G F P+ +F + G + L ++L
Sbjct: 268 FRLCGSPTQATMPNWEKLPGCEG----VRSFPSHPRTLETAFFTF-GKEMTSLCGAILTL 322
Query: 303 EPERRASPRRILAHPFF 319
P+ R S L H +F
Sbjct: 323 NPDERLSASMALEHEYF 339
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 117 bits (294), Expect = 2e-26
Identities = 95/301 (31%), Positives = 149/301 (48%), Gaps = 34/301 (11%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
+IG+G +G V +A T A+K++ + E RE++IL+ H N+V
Sbjct: 282 QIGEGTYGKVYKAINTVTGDL----VALKRIRLEQEKDGFPITTVREVKILQRLRHKNIV 337
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+L S + +++++ + L +L N L + N+ KH+ + QI +
Sbjct: 338 RLLEIMVEKSSV-YMVFEYMDHD-LTGVLLNSQLHFTPGNI----KHL---SKQIFEALA 388
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPEL 202
YLH G+ HRDIK SN+L++ G LK DFG A+ ++ S +Y + + ++R PEL
Sbjct: 389 YLHHRGVLHRDIKGSNILLN-NNGDLKFADFGLAR-FNTSSKSANYTNRVITLWFRPPEL 446
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G T Y T +DIW GC++ E+ GK FQG + QL I ++G PD S P
Sbjct: 447 LLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPD----VHSWPE 502
Query: 263 Y-NGPLFS--KPLFEGAPKARF-EKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
N P + KP+ E K+RF E + P +DL +L P R S L H +
Sbjct: 503 VKNLPWYELLKPVEE--KKSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEY 560
Query: 319 F 319
F
Sbjct: 561 F 561
>Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 117 bits (293), Expect = 3e-26
Identities = 108/341 (31%), Positives = 162/341 (46%), Gaps = 61/341 (17%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
IG+G+FG VV+AY Q+ + IK A EL +L + + + +++Y+
Sbjct: 117 IGKGSFGQVVKAY-DHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDT-EMKYYIV 174
Query: 93 HISPTDHKLYQH---LAMECLP----EMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
H+ H ++++ L E L ++L+N R NL L A Q+ +L
Sbjct: 175 HLKR--HFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKL------AQQLCTALL 226
Query: 146 YLHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE+
Sbjct: 227 FLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEV 284
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G T Y ID+W LGC+L EM G+ +F G + Q++ I ++LG P
Sbjct: 285 LLG-TPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIP----------- 332
Query: 263 YNGPLFSKPLFEGAPKAR--FEKYFG--------------YAGPD----GVDLLMSVLVY 302
+ + APKAR FE+ G Y GP DL++ +L Y
Sbjct: 333 ------PAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEDLVLRMLEY 386
Query: 303 EPERRASPRRILAHPFFDDLRNE-RYFFPSGSSQPKHLPPL 342
EP R SP L H FF +E P+GSS PL
Sbjct: 387 EPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPL 427
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 117 bits (292), Expect = 3e-26
Identities = 87/305 (28%), Positives = 144/305 (46%), Gaps = 29/305 (9%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILRIADHPNVV 85
IG+G +G V +A K G A+KKV E + RE++ILR H +VV
Sbjct: 733 IGEGTYGQVYKA-----RDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVV 787
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNL-ELPLKHVKLYAYQIARGM 144
++ T A + E + ++++ ++ L H+K + Q+ G+
Sbjct: 788 NMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGL 847
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYICSRYYRAPEL 202
Y H HRDIK SN+L++ +G +K+ DFG A+ E ++P + + + +YR PEL
Sbjct: 848 EYCHKKNFLHRDIKCSNILLN-NSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPEL 906
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +YT ID+W GC+LGE+ K +FQ + L QL I++L G P P+
Sbjct: 907 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSP--------CPA 958
Query: 263 YNGPLFSKPLFEGAP-----KARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
+ P F + R + F + +DLL +L +P +R + + L
Sbjct: 959 VWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSD 1018
Query: 318 FFDDL 322
F D+
Sbjct: 1019 FLKDV 1023
>CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 117 bits (292), Expect = 3e-26
Identities = 97/321 (30%), Positives = 149/321 (46%), Gaps = 48/321 (14%)
Query: 71 RELEILRIADHPNVVKLEYFYTHISPTDHKL----------YQHLAMECLPEMLQNEILR 120
REL + + NVVK+ Y+ +P ++ L Y H M+ L NE
Sbjct: 68 RELNCMLNIEDDNVVKM---YSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGH 124
Query: 121 YKKNNLELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK 180
+ VK + I RG+ YLHA+ I HRD+KP N+L++ Q G +K+CDFG +
Sbjct: 125 ----------RTVKSIFFDICRGVQYLHAMRISHRDLKPENILMN-QEGDVKLCDFGHSN 173
Query: 181 KLESNQPSISYICSRYYRAPELIVGCTQYT-TKIDIWGLGCVLGEMLLGKAVFQGHQPLL 239
K E + YI R+YRAPE+I T T +DIW LGC+L E+L G +F+G +
Sbjct: 174 K-EDPTSNTPYIVQRFYRAPEIICETTDNNKTNVDIWSLGCILAELLTGHVLFRGKDHID 232
Query: 240 QLHEITKLLGPPDKRFIFFSNP-------SYNGPLFSKPL--FEGAPKARFEKYFGYAGP 290
Q + + LG F N YN + P+ + P F+ +
Sbjct: 233 QFILMVQFLGNAGPSFYSQMNEHARNFLLRYNLDQYQAPINFYSRFPDTVFQGVLQFEPK 292
Query: 291 D---GVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPP--LYDF 345
+ DLL +LV P+ R + + +L+HP+ ++ E + P+ PP L F
Sbjct: 293 ECDMSRDLLFRMLVINPDDRLNIQMVLSHPYLREIWGE---IVAEDVIPEPQPPNELLRF 349
Query: 346 SDFE-----LQVIGDLFPKIQ 361
DF+ L + ++F KI+
Sbjct: 350 FDFQPYSSPLDMREEIFQKIK 370
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 117 bits (292), Expect = 3e-26
Identities = 92/341 (26%), Positives = 161/341 (46%), Gaps = 39/341 (11%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ ++IG+G +G V A + A+KK+ E + RE++IL+ H
Sbjct: 27 EKLEQIGEGTYGQVYMAKEIKTGEI----VALKKIRMDNEREGFPITAIREIKILKKLHH 82
Query: 82 PNVVKLEYFYTHIS--------PTDHKLYQHLAMECLPEMLQNEILRYK-KNNLELPLKH 132
NV++L+ T P ++K + M + E + +++ + L +
Sbjct: 83 ENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYM--VFEYMDHDLTGLADRPGLRFTVPQ 140
Query: 133 VKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS--IS 190
+K Y Q+ G+ Y H + HRDIK SN+L+D + G LK+ DFG A+ + +
Sbjct: 141 IKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNE-GNLKLADFGLARSYSHDHTGNLTN 199
Query: 191 YICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP 250
+ + +YR PEL++G T+Y ID+W +GC+ E+L K + G QL++I +L G
Sbjct: 200 RVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGS 259
Query: 251 PDKRFI--FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRA 308
PD++ P +N ++PL K R ++F + ++LL +LV +P +R
Sbjct: 260 PDEKLWPGVSKMPWFNNFKPARPL-----KRRVREFFRHFDRHALELLEKMLVLDPAQRI 314
Query: 309 SPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFSDFE 349
S + D L E ++ PK LP +F+
Sbjct: 315 SAK--------DALDAEYFWTDPLPCDPKSLPTYESSHEFQ 347
>At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 932
Score = 117 bits (292), Expect = 3e-26
Identities = 100/326 (30%), Positives = 156/326 (47%), Gaps = 36/326 (11%)
Query: 24 EMLVKEYKRI---GQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA-QTEYKSRELE--ILR 77
E+L Y+ I G+G F TVV+A AIK + +T +K+ ++E IL+
Sbjct: 608 ELLDGRYEVIATHGKGVFSTVVRAKDLKAGPAEPEEVAIKIIRNNETMHKAGKIEVQILK 667
Query: 78 IADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYA 137
+ + +S ++ + L E L L+ E+L+ N+ L L V+ Y+
Sbjct: 668 KLAGADREDRRHCVRFLSSFKYRNHLCLVFESLHLNLR-EVLKKFGRNIGLQLSAVRAYS 726
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYY 197
Q+ + +L G+ H DIKP N+LV+ +LK+CDFG+A N+ + Y+ SR+Y
Sbjct: 727 KQLFIALKHLKNCGVLHCDIKPDNMLVNEGKNVLKLCDFGNAMFAGKNEVT-PYLVSRFY 785
Query: 198 RAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQG--HQPLLQLHEITKLLGP----- 250
R+PE+I+G T Y +DIW +GC L E+ GK +F G + +L+LH +L GP
Sbjct: 786 RSPEIILGLT-YDHPLDIWSVGCCLYELYSGKVLFPGATNNDMLRLH--MELKGPFPKKM 842
Query: 251 ------------PDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGV----- 293
D F + +G L + + PK GY G D
Sbjct: 843 LRKGAFIDQHFDHDLNFYATEEDTVSGKLIKRMIVNVKPKDFGSIIKGYPGEDPKILAHF 902
Query: 294 -DLLMSVLVYEPERRASPRRILAHPF 318
DLL + + +PERR + + LAHPF
Sbjct: 903 RDLLDKMFILDPERRLTVSQALAHPF 928
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 117 bits (292), Expect = 3e-26
Identities = 92/322 (28%), Positives = 152/322 (46%), Gaps = 36/322 (11%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADH 81
++ + IGQG + +V +A NQ A+KKV P + +RE+ ILR +H
Sbjct: 147 EKLEMIGQGTYSSVYRARDLETNQI----VALKKVRFANMDPESVRFMAREIIILRRLNH 202
Query: 82 PNVVKLE-YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQI 140
PNV+KLE + S + + +++++ + L + +++ + A Q+
Sbjct: 203 PNVMKLEGLIISKASGSMYLIFEYMDHD-LAGLASTPGIKFSQ-------------AQQL 248
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYICSRYYR 198
G+ + H+ G+ HRDIK SN+L+D LKI DFG + + + QP S + + +YR
Sbjct: 249 LLGLEHCHSCGVLHRDIKCSNLLLDRNNN-LKIGDFGLSNFYRGQRKQPLTSRVVTLWYR 307
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFF 258
PEL++G T Y +D+W GC+L E+ GK + G + Q+H+I KL G P + ++
Sbjct: 308 PPELLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEE--YW 365
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
KP + K F + LL +L EP+ R + L F
Sbjct: 366 RRSRLRHATIFKP--QHPYKRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEF 423
Query: 319 FDDLRNERYFFPSGSSQPKHLP 340
F + F SS P++ P
Sbjct: 424 F----TTKPFPSEPSSLPRYQP 441
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 117 bits (292), Expect = 3e-26
Identities = 94/330 (28%), Positives = 159/330 (47%), Gaps = 35/330 (10%)
Query: 22 KREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-----RELEIL 76
K+E VK + +G+G++ TV + + Q+ A+K++ Q E + RE +L
Sbjct: 188 KQEAYVK-LEPLGEGSYATVYKGFSKLTYQR----VALKEIRLQEEEGAPFTAIREASLL 242
Query: 77 RIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLY 136
+ H N+V L + H T +++++ + M +K+ L ++V+L+
Sbjct: 243 KELKHSNIVTL-HDIVHTRETLTFVFEYVNTDLSQYM--------EKHPGGLDHRNVRLF 293
Query: 137 AYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---IC 193
+Q+ RG+ Y H + HRD+KP N+L+ G LK+ DFG A+ + PS +Y +
Sbjct: 294 LFQLLRGLSYCHKRRVLHRDVKPQNLLIS-DCGELKLADFGLARA--KSVPSHTYSHEVV 350
Query: 194 SRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL-QLHEITKLLGPPD 252
+ +YR P++++G T+Y+T +D+WG+GC+ EM+ G F G + QL +I KLLG P
Sbjct: 351 TLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPT 410
Query: 253 KR----FIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRA 308
+ F + F +P G R Y +G + L PE+R
Sbjct: 411 EDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRL-----YDIIEGETIANGFLQLNPEQRL 465
Query: 309 SPRRILAHPFFDDLRNERYFFPSGSSQPKH 338
L HP+F L + Y P G + H
Sbjct: 466 GADDALQHPYFAQLPKKLYELPDGENLNFH 495
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 116 bits (291), Expect = 5e-26
Identities = 79/250 (31%), Positives = 132/250 (52%), Gaps = 13/250 (5%)
Query: 71 RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPL 130
RE+ +++ HPN++ L + + T++KL L E + + L+ + Y N LP
Sbjct: 48 REISLMKELRHPNIMSL----SDVLQTENKLM--LVFEYMEKDLKKYMDTYG-NQGALPP 100
Query: 131 KHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS 190
VK + Q+ +G+ + H + HRD+KP N+L++ + G LK+ DFG A+ + + S
Sbjct: 101 SQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSR-GELKLADFGLARSIGIPVNTFS 159
Query: 191 Y-ICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG 249
+ + +YRAP++++G Y+T IDIW +GC++ EM G+ +F G QL +I +LLG
Sbjct: 160 NEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLG 219
Query: 250 PPDKRFIFFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRAS 309
P ++ S P + KP F F P G+DLL +L +PE R +
Sbjct: 220 TPTEQ----SWPGISLLPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTT 275
Query: 310 PRRILAHPFF 319
+ L H +F
Sbjct: 276 GQDALQHAWF 285
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 116 bits (291), Expect = 5e-26
Identities = 90/306 (29%), Positives = 146/306 (47%), Gaps = 27/306 (8%)
Query: 27 VKEYK---RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILR 77
VKE++ RIG+G +G V +A T ++ A+KKV E RE+ +L
Sbjct: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEI----VALKKVRMDKEKDGIPISSLREITLLL 91
Query: 78 IADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYA 137
HPN+V+L+ L + L +L+N + + VK
Sbjct: 92 RLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSE-------AQVKCIV 144
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRY 196
Q+ RG+ YLH I HRD+K SN+L+ + G +K DFG A+ +P + + +
Sbjct: 145 LQVLRGLQYLHRNFIIHRDLKVSNLLMTDK-GCVKTADFGLARAYGVPVKPMTPKVVTLW 203
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI 256
YRAPEL++G T TT ID+W +GC+L E+L + + G + Q+ I +LLG P +
Sbjct: 204 YRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIW 263
Query: 257 FFSNPSYNG-PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
P ++ PL + P + F + G+ LL + +Y+P++RA+ L
Sbjct: 264 ----PGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLE 319
Query: 316 HPFFDD 321
+F +
Sbjct: 320 SSYFKE 325
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 116 bits (291), Expect = 5e-26
Identities = 76/225 (33%), Positives = 120/225 (52%), Gaps = 18/225 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADHPNVVK 86
+G GA+G+V A+ T + A+KK+ P Q+ + REL +L+ H NV+
Sbjct: 30 VGSGAYGSVCAAFDTKTGLR----VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIG 85
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L +T + +L + L N I++ +K L HV+ YQI RG+ Y
Sbjct: 86 LLDVFTPARSLEEFNDVYLVTHLMGADLNN-IVKCQK----LTDDHVQFLIYQILRGLKY 140
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ I HRD+KPSN+ V+ LKI DFG A+ + Y+ +R+YRAPE+++
Sbjct: 141 IHSADIIHRDLKPSNLAVNEDCE-LKILDFGLARHTDDEMTG--YVATRWYRAPEIMLNW 197
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP 251
Y +DIW +GC++ E+L G+ +F G + QL I +L+G P
Sbjct: 198 MHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 116 bits (291), Expect = 5e-26
Identities = 76/225 (33%), Positives = 120/225 (52%), Gaps = 18/225 (8%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKS----RELEILRIADHPNVVK 86
+G GA+G+V A+ T + A+KK+ P Q+ + REL +L+ H NV+
Sbjct: 30 VGSGAYGSVCAAFDTKTGLR----VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIG 85
Query: 87 LEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
L +T + +L + L N I++ +K L HV+ YQI RG+ Y
Sbjct: 86 LLDVFTPARSLEEFNDVYLVTHLMGADLNN-IVKCQK----LTDDHVQFLIYQILRGLKY 140
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
+H+ I HRD+KPSN+ V+ LKI DFG A+ + Y+ +R+YRAPE+++
Sbjct: 141 IHSADIIHRDLKPSNLAVNEDCE-LKILDFGLARHTDDEMTG--YVATRWYRAPEIMLNW 197
Query: 207 TQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPP 251
Y +DIW +GC++ E+L G+ +F G + QL I +L+G P
Sbjct: 198 MHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 116 bits (291), Expect = 5e-26
Identities = 90/306 (29%), Positives = 146/306 (47%), Gaps = 27/306 (8%)
Query: 27 VKEYK---RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILR 77
VKE++ RIG+G +G V +A T ++ A+KKV E RE+ +L
Sbjct: 7 VKEFEKLNRIGEGTYGIVYRARDTQTDEI----VALKKVRMDKEKDGIPISSLREITLLL 62
Query: 78 IADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYA 137
HPN+V+L+ L + L +L+N + + VK
Sbjct: 63 RLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSE-------AQVKCIV 115
Query: 138 YQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRY 196
Q+ RG+ YLH I HRD+K SN+L+ + G +K DFG A+ +P + + +
Sbjct: 116 LQVLRGLQYLHRNFIIHRDLKVSNLLMTDK-GCVKTADFGLARAYGVPVKPMTPKVVTLW 174
Query: 197 YRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI 256
YRAPEL++G T TT ID+W +GC+L E+L + + G + Q+ I +LLG P +
Sbjct: 175 YRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIW 234
Query: 257 FFSNPSYNG-PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILA 315
P ++ PL + P + F + G+ LL + +Y+P++RA+ L
Sbjct: 235 ----PGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLE 290
Query: 316 HPFFDD 321
+F +
Sbjct: 291 SSYFKE 296
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 116 bits (291), Expect = 5e-26
Identities = 86/299 (28%), Positives = 138/299 (45%), Gaps = 22/299 (7%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLG---------PFAIKKVPAQTEYKSRELEILRIADH 81
+R+G+G + + Y K L P AIKK+ + E+ +R
Sbjct: 8 RRLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIREIKS 67
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIA 141
+ +Y I + H+ +E + L+N I K + +P +K + +
Sbjct: 68 LKRIDSKYVVRLIDTFVYDKCVHIVLEYVETNLENVIRNSDK--IIMP-GDIKAWILMVL 124
Query: 142 RGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPE 201
RG+ H L I HRDIKP+N+L+ + G++K+ DFG + + + + +R+YRAPE
Sbjct: 125 RGVYECHRLFIIHRDIKPNNILITSE-GMVKLADFGLTRGIGNRMTPQAV--TRWYRAPE 181
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNP 261
L++G Y + +D+W +GCV E+ L +F G + QL I + LG P +R P
Sbjct: 182 LLMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVER----EWP 237
Query: 262 SYNG-PLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ P F F+ PKA F A D +DLL +L P R S + HP+F
Sbjct: 238 GVSTLPEFLD--FQQYPKASLNGLFSAASSDALDLLEKLLTLNPCNRISCDDAIKHPYF 294
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 116 bits (291), Expect = 5e-26
Identities = 98/317 (30%), Positives = 145/317 (44%), Gaps = 46/317 (14%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP--------AQTEYKSRELEILRIADHP 82
K + GA G VV A Q+ AIKK+ A+ Y RE +L HP
Sbjct: 33 KFLNVGAQGIVVMADDLVTTQR----VAIKKMQQPFLLTMSARRAY--REFILLTTLKHP 86
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+++L +T + +L ME + L I R L L + + YQ
Sbjct: 87 NIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHR-----LRLDHETLSFLVYQSLC 141
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+ +LH LG HRD+KPSN++V+ + +LK+ DFG A++ + Y+ +RYYRAPE+
Sbjct: 142 AIKHLHNLGFIHRDLKPSNIVVNERC-VLKVLDFGLARRRNVDMRMSDYVGTRYYRAPEV 200
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
I+G Y+ K+DIW +GC+L EM+ +F G Q +I+ +L PD FI P
Sbjct: 201 ILGLN-YSEKVDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLEPI 259
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPD------------------GVDLLMSVLVYEP 304
G ++ + L + +A F PD DLL ++L P
Sbjct: 260 --GAVYVRSLPQHLARA-----FNEIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINP 312
Query: 305 ERRASPRRILAHPFFDD 321
E R S L HP+ D
Sbjct: 313 EERYSVEDALNHPYTMD 329
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 116 bits (291), Expect = 5e-26
Identities = 87/301 (28%), Positives = 147/301 (47%), Gaps = 19/301 (6%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
RI +G +G V +A N+ A+K++ + E + RE+ L HPN+V
Sbjct: 563 RIEEGTYGVVYRAKDKRTNEI----VALKRLKMEKEKEGFPITSLREINTLLKGQHPNIV 618
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ + K++ + M+ + L++ + K VK Q+ R +
Sbjct: 619 TVREIV--VGSNMDKIF--IVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVA 674
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN-QPSISYICSRYYRAPELIV 204
+LH I HRD+K SN+L+ + GILK+ DFG A++ S + S + + +YRAPEL++
Sbjct: 675 HLHDNWILHRDLKTSNLLLSHK-GILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLL 733
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--FFSNPS 262
Y+T ID+W +GC+ E L +F G + +L+ I K LG P+++ + P+
Sbjct: 734 CSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPA 793
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPD-GVDLLMSVLVYEPERRASPRRILAHPFFDD 321
L F P ++ K+F + G+ LL +L Y+P++R S L H FF +
Sbjct: 794 VKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKE 853
Query: 322 L 322
L
Sbjct: 854 L 854
>SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4
Length = 477
Score = 116 bits (290), Expect = 6e-26
Identities = 103/323 (31%), Positives = 147/323 (44%), Gaps = 49/323 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRE-------LEILRIADHPNVV 85
+G+G F TVV A NQ FAIK + E +E LE L+ AD
Sbjct: 165 LGKGMFSTVVSALDRNRNQT----FAIKII-RNNEVMYKEGLKEVSILERLQAADREGKQ 219
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
+ ++ H HK + + E L L+ +IL+ N+ L +K V+LYAYQ+ +
Sbjct: 220 HIIHYERHFM---HKNHLCMVFEMLSLNLR-DILKKFGRNVGLSIKAVRLYAYQMFMALD 275
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVG 205
L + H DIKP N+LV+ + ILKICD GSA N+ + Y+ SR+YRAPE+I+G
Sbjct: 276 LLKQCNVIHSDIKPDNMLVNEKRNILKICDLGSASDASENEIT-PYLVSRFYRAPEIILG 334
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG---------------- 249
Y+ ID W +GC L E+ G+ +F G L + + G
Sbjct: 335 -FPYSCPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKGKFSHKMLKRSQFLNDH 393
Query: 250 -PPDKRFIF-----FSNPSYNGPL-FSKPL------FEGAPKARFEKYFGYAGPDGVDLL 296
D FI +N P+ FSKP + P + E++ + +DLL
Sbjct: 394 FDADFNFIQIDHDPITNQETRKPVKFSKPTKDIRSRLKEVPTSTDEEFI--IRQELMDLL 451
Query: 297 MSVLVYEPERRASPRRILAHPFF 319
L PE+R P L HPFF
Sbjct: 452 EKCLELNPEKRVPPEVALKHPFF 474
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 116 bits (290), Expect = 6e-26
Identities = 76/296 (25%), Positives = 147/296 (48%), Gaps = 26/296 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-RELEILRIADHPNVVKLEY 89
+++G G +G+V+ + +K + E + RE++ L+ +H NV+KL+
Sbjct: 8 RQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKE 67
Query: 90 FYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHA 149
I DH + M +N K N P ++ YQI +G+ ++H
Sbjct: 68 V---IRENDHLYF------IFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHK 118
Query: 150 LGICHRDIKPSNVL-VDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQ 208
G HRD+KP N+L + P+ ++KI DFG A++L S P Y+ +R+YRAPE+++ +
Sbjct: 119 HGFFHRDMKPENLLCMGPE--LVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSV 176
Query: 209 YTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR-----FIFFSNPSY 263
Y++ ID+W +G ++ E+ + + +F G + ++ +I ++LG P K + S+ ++
Sbjct: 177 YSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNF 236
Query: 264 NGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
F + A + + L+ +L ++P++R + + L HP+F
Sbjct: 237 R--------FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 115 bits (287), Expect = 1e-25
Identities = 90/315 (28%), Positives = 153/315 (48%), Gaps = 30/315 (9%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEY-----KSRELEILRIADHPNVV 85
+++G+G++ TV + + Q A+K + E RE +L+ H N+V
Sbjct: 56 EKLGEGSYATVYKGISRINGQL----VALKVISMNAEEGVPFTAIREASLLKGLKHANIV 111
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
L + H T +++++ + M Q+ + N V+L+ +Q+ RG+
Sbjct: 112 LL-HDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHN--------VRLFMFQLLRGLA 162
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK-KLESNQPSISYICSRYYRAPELIV 204
Y+H + HRD+KP N+L+ G LK+ DFG A+ K +Q S + + +YR P+ ++
Sbjct: 163 YIHHQHVLHRDLKPQNLLIS-HLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALL 221
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL-QLHEITKLLGPP--DKRFIFFSNP 261
G T+Y++++DIWG GC+ EM G+ +F G +L QL +I ++LG P D P
Sbjct: 222 GATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLP 281
Query: 262 SYNGPLFSKPLFEGAPKARFEKYFGYAG--PDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+YN F P P++ + G P+ DL +L P R S + L H +F
Sbjct: 282 NYNPEWFPLP----TPRS-LHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYF 336
Query: 320 DDLRNERYFFPSGSS 334
L ++ Y P S
Sbjct: 337 SALPSQLYQLPDEES 351
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 115 bits (287), Expect = 1e-25
Identities = 95/346 (27%), Positives = 160/346 (45%), Gaps = 49/346 (14%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ ++IG+G +G V A + A+KK+ E + RE++IL+ H
Sbjct: 27 EKLEQIGEGTYGQVYMAKEIKTGEI----VALKKIRMDNEREGFPITAIREIKILKKLHH 82
Query: 82 PNVVKLEYFYTHIS--------PTDHKLYQHLAMECLPEMLQNEILRYK-KNNLELPLKH 132
NV+ L+ T P ++K + M + E + +++ + L +
Sbjct: 83 ENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYM--VFEYMDHDLTGLADRPGLRFTVPQ 140
Query: 133 VKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPS--IS 190
+K Y Q+ G+ Y H + HRDIK SN+L+D + G LK+ DFG A+ + +
Sbjct: 141 IKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNE-GNLKLADFGLARSYSHDHTGNLTN 199
Query: 191 YICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGP 250
+ + +YR PEL++G T+Y ID+W +GC+ E+L GK + G QL++I +L G
Sbjct: 200 RVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGS 259
Query: 251 PDKRFIFFSN-------PSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYE 303
PD+ SN P YN S+PL K R + + + ++LL +LV +
Sbjct: 260 PDE-----SNWPGVSKMPWYNQMKSSRPL-----KRRVREIYRHFDRHALELLEKMLVLD 309
Query: 304 PERRASPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYDFSDFE 349
P +R + D L E ++ PK LP +F+
Sbjct: 310 PSQRICAK--------DALDAEYFWTDPLPCDPKSLPTYESSHEFQ 347
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 114 bits (286), Expect = 2e-25
Identities = 81/254 (31%), Positives = 127/254 (49%), Gaps = 32/254 (12%)
Query: 26 LVKEY---KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEIL 76
+V+ Y +++GQGA+G V +A +++ AIKK+ + RE+ +L
Sbjct: 9 IVRRYLLRRQLGQGAYGIVWKAV----DRRTGEVVAIKKIFDAFRDKTDAQRTFREITLL 64
Query: 77 R-IADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLK---- 131
+ DHPN++ L + D L M C P +R + +L
Sbjct: 65 QEFGDHPNIISLLDVIRAENDRDIYLVFEF-MGCPPSPPPPTAVRTLSADTDLNAVIRKG 123
Query: 132 ------HVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL--- 182
HV+ YQ+ R +LH+ + HRD KPSNVL+D + K+CDFG A+ L
Sbjct: 124 GLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTV-KLCDFGLARSLGDL 182
Query: 183 ---ESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL 239
+Q Y+ +R+YRAPE+++ +YT +D+W LGC+LGEML G+ +F G L
Sbjct: 183 PEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLH 242
Query: 240 QLHEITKLLGPPDK 253
QL I + + PP +
Sbjct: 243 QLELILETIPPPSE 256
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 114 bits (285), Expect = 2e-25
Identities = 88/324 (27%), Positives = 151/324 (46%), Gaps = 41/324 (12%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILRIADHPNVV 85
IG+G +G V +A K G A+KKV E + RE++ILR H +++
Sbjct: 711 IGEGTYGQVYKA-----RDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSII 765
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNL-ELPLKHVKLYAYQIARGM 144
++ T A + E + ++++ ++ L H+K + Q+ G+
Sbjct: 766 NMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGL 825
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYICSRYYRAPEL 202
Y H HRDIK SN+L++ + G +K+ DFG A+ E ++P + + + +YR PEL
Sbjct: 826 DYCHKKNFLHRDIKCSNILLNNR-GQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL 884
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +YT ID+W GC+LGE+ K +FQ +Q L QL I+++ G P P+
Sbjct: 885 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSP--------CPA 936
Query: 263 YNGPLFSKPLFEG-APKARFEK----YFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
+ P F PK ++ + F + +DL +L +P +R + + L
Sbjct: 937 VWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCE 996
Query: 318 FFDDLRNERYFFPSGSSQPKHLPP 341
F D+ +P +PP
Sbjct: 997 FLRDV------------EPSKMPP 1008
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 114 bits (285), Expect = 2e-25
Identities = 88/324 (27%), Positives = 151/324 (46%), Gaps = 41/324 (12%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILRIADHPNVV 85
IG+G +G V +A K G A+KKV E + RE++ILR H +++
Sbjct: 711 IGEGTYGQVYKA-----RDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSII 765
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNL-ELPLKHVKLYAYQIARGM 144
++ T A + E + ++++ ++ L H+K + Q+ G+
Sbjct: 766 NMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGL 825
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK--KLESNQPSISYICSRYYRAPEL 202
Y H HRDIK SN+L++ + G +K+ DFG A+ E ++P + + + +YR PEL
Sbjct: 826 DYCHKKNFLHRDIKCSNILLNNR-GQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL 884
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
++G +YT ID+W GC+LGE+ K +FQ +Q L QL I+++ G P P+
Sbjct: 885 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSP--------CPA 936
Query: 263 YNGPLFSKPLFEG-APKARFEK----YFGYAGPDGVDLLMSVLVYEPERRASPRRILAHP 317
+ P F PK ++ + F + +DL +L +P +R + + L
Sbjct: 937 VWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCE 996
Query: 318 FFDDLRNERYFFPSGSSQPKHLPP 341
F D+ +P +PP
Sbjct: 997 FLRDV------------EPSKMPP 1008
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 114 bits (285), Expect = 2e-25
Identities = 68/225 (30%), Positives = 119/225 (52%), Gaps = 12/225 (5%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYF 90
K++G+GAFG V ++ T D FAIKK+P E I I +V+
Sbjct: 8 KQVGEGAFGQVYKSRRTSDG----AVFAIKKMPVDRETGFPFTAIREIKLCKSVIN---- 59
Query: 91 YTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHAL 150
HI D +++ + + E + ++ + +L ++ Q+ + +H +
Sbjct: 60 -KHIIGLDEIVFEEGFIFVVLEYMPYDLTGLLASGAKLSTDQIRSITSQLIEAVSSMHGM 118
Query: 151 GICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQYT 210
G+ HRDIKPSN+L+D G+LK+ DFG +++ + +C+ +YRAPEL++G T Y+
Sbjct: 119 GLVHRDIKPSNILLDCH-GMLKLTDFGLTREISGMMTN--RVCTLWYRAPELLLGETSYS 175
Query: 211 TKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
K+D W +GC++ EM LG+ ++G + Q+ I + LG P ++
Sbjct: 176 LKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDKY 220
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 114 bits (284), Expect = 3e-25
Identities = 90/310 (29%), Positives = 154/310 (49%), Gaps = 38/310 (12%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS-----RELEILRIADH 81
K+ +++G G + TV + K G + A+K+V +E + RE+ +++ H
Sbjct: 8 KQLEKLGNGTYATVYKGL-----NKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLE------LPLKHVKL 135
N+V+L Y H T++KL + E + N++ +Y + L L VK
Sbjct: 63 ENIVRL-YDVIH---TENKL------TLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKY 112
Query: 136 YAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICS 194
+ +Q+ +G+ + H I HRD+KP N+L++ + G LK+ DFG A+ + S + +
Sbjct: 113 FQWQLLQGLAFCHENKILHRDLKPQNLLINKR-GQLKLGDFGLARAFGIPVNTFSSEVVT 171
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
+YRAP++++G Y+T IDIW GC+L EM+ GK +F G QL I ++G P++
Sbjct: 172 LWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNES 231
Query: 255 F--IFFSNPSYNGPLFSKP---LFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRAS 309
P YN + +P L + E G + +D L +L P+ R S
Sbjct: 232 LWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDG----NLMDFLHGLLQLNPDMRLS 287
Query: 310 PRRILAHPFF 319
++ L HP+F
Sbjct: 288 AKQALHHPWF 297
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 113 bits (283), Expect = 4e-25
Identities = 85/303 (28%), Positives = 147/303 (48%), Gaps = 21/303 (6%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPF-AIKKVPAQTEYKS------RELEILRIAD 80
++ ++IG+G +G V +A K G A+KK+ + E + RE+ +L+ +
Sbjct: 5 QKVEKIGEGTYGVVYKA-----RHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVN 59
Query: 81 HPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNL-ELPLKHVKLYAYQ 139
N I + KLY L E L L+ + R + L + V+ + YQ
Sbjct: 60 DENNRSNCVRLLDILHAESKLY--LVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQ 117
Query: 140 IARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYR 198
+ G+ + H+ I HRD+KP N+L+D + G LK+ DFG A+ + ++ I + +YR
Sbjct: 118 LVNGVNFCHSRRIIHRDLKPQNLLIDKE-GNLKLADFGLARSFGVPLRNYTHEIVTLWYR 176
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFF 258
APE+++G Y+T +DIW +GC+ EM+ +F G + ++ +I ++LG P++
Sbjct: 177 APEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVW-- 234
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
P K F + K D ++LL ++LVY+P R S +R L +
Sbjct: 235 --PGVTLLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNY 292
Query: 319 FDD 321
D
Sbjct: 293 LRD 295
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 113 bits (283), Expect = 4e-25
Identities = 70/231 (30%), Positives = 130/231 (55%), Gaps = 14/231 (6%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEI---LRIADHPNVVKL 87
+++G G FG+V A +++ + ++KK A+ +R E+ LR++++ N+V +
Sbjct: 40 RKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENENIVNI 99
Query: 88 EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
Y D H+ ME L L +++ +KN+ L L+ V+ QI +G+ ++
Sbjct: 100 FDLYI-----DQFRCLHIVMEFLDCNLY-QLISTRKND-PLTLEQVQDIMRQIFKGLNHI 152
Query: 148 HALGICHRDIKPSNVLV----DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
H G HRD+KP N+L+ D + +KI DFG A+++ S P Y+ +R+YRAPEL+
Sbjct: 153 HTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELL 212
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
+ + Y+ +DI+ GC+ E+ + +F G+ QL+++ ++LG PD++
Sbjct: 213 LRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQ 263
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 113 bits (283), Expect = 4e-25
Identities = 67/204 (32%), Positives = 109/204 (52%), Gaps = 11/204 (5%)
Query: 126 LELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESN 185
+EL + + YQ+ G+ +LH+ GI HRD+KPSN++V LKI DFG A+ ++
Sbjct: 14 MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC-TLKILDFGLARTAGTS 72
Query: 186 QPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEIT 245
Y+ +RYYRAPE+I+G Y +DIW +GC++GEM+ K +F G + Q +++
Sbjct: 73 FMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVI 131
Query: 246 KLLGPPDKRFIFFSNPSYNGPLFSKPLFEGA------PKARF---EKYFGYAGPDGVDLL 296
+ LG P F+ P+ + ++P + G P + F ++ DLL
Sbjct: 132 EQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLL 191
Query: 297 MSVLVYEPERRASPRRILAHPFFD 320
+LV +P +R S L HP+ +
Sbjct: 192 SKMLVIDPAKRISVDDALQHPYIN 215
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 113 bits (283), Expect = 4e-25
Identities = 90/299 (30%), Positives = 143/299 (47%), Gaps = 29/299 (9%)
Query: 30 YKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV-PAQTEYKSRELEILRIADHPNVVKLE 88
Y+R+G+G + V + D +K IK + P + RE+ ILR H N++KL
Sbjct: 40 YQRMGRGKYSEVFEG--RKDREK----IVIKALKPVRKAKICREVLILRNLSHKNIIKL- 92
Query: 89 YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH 148
+ + ++Y + E +++E Y K +L K + Y+ QI + Y H
Sbjct: 93 --MDVVVDPESQIYSLIF-----EYIEHE--DYAKIFEKLCYKDIVEYSRQILSALSYCH 143
Query: 149 ALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQ 208
++GI HRDIKP N++++ LKI D+G A+ + + SRYY+ PEL+V
Sbjct: 144 SMGIIHRDIKPQNMVINQARRELKIIDWGLAEFYHPKKEYSVRVASRYYKGPELLVDYPY 203
Query: 209 YTTKIDIWGLGCVLGEMLLGK-AVFQGHQPLLQLHEITKLLGPPD-KRFIFFSNPSYNGP 266
Y +DIW GCVL E++ K F G QL +I ++LG K+++ P
Sbjct: 204 YDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKKYV---RKYKMAP 260
Query: 267 LFSKPLFEGAPKARFEKYFGYAGPDG-----VDLLMSVLVYEPERRASPRRILAHPFFD 320
L P +EG + F G G +DLL +L+Y+ + R + L HP F+
Sbjct: 261 L--NPKYEGVGERVLLSSFTPPGKTGLYTNAIDLLEKILIYDHQDRPTADECLRHPLFE 317
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 113 bits (283), Expect = 4e-25
Identities = 93/334 (27%), Positives = 164/334 (48%), Gaps = 31/334 (9%)
Query: 27 VKEYK---RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELE-IL 76
+ EY+ R+ +G FG V + +++ A+K++ + E + RE+ +L
Sbjct: 353 IDEYECVNRVDEGTFGVVYRG----KDKRTDEIVALKRLKMEKEKEGFPITALREINMLL 408
Query: 77 RIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLY 136
+ +HPN+V ++ + K+Y +AME + +++ + + N + K
Sbjct: 409 KAGNHPNIVNVKEIL--LGSNMDKIY--MAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTL 464
Query: 137 AYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL-ESNQPSISYICSR 195
Q+ G+ ++H L I HRD+K SN+L+ + GILKI DFG A++ + + S + +
Sbjct: 465 LQQLLSGIEHMHKLWILHRDLKTSNLLMSHK-GILKIADFGLAREYGDPLKKFTSIVVTL 523
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
+YR+PEL++G Y+T +D+W +GC++ E +L K +F G L Q+ +I +G P +
Sbjct: 524 WYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTES- 582
Query: 256 IFFSNPSYNGPLFSKPLFEGAPKARFEKYF---GYAGPDGVDLLMSVLVYEPERRASPRR 312
I+ +G + FE P + K F G LL +L +P+ R S +
Sbjct: 583 IWPGVTELDG--WKALTFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQ 640
Query: 313 ILAHPFFDD-----LRNERYFFPSGSSQPKHLPP 341
L H +F + E FP+ S Q K PP
Sbjct: 641 ALDHEWFTEEPYPVPPEEFPTFPAKSEQNKAPPP 674
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 113 bits (282), Expect = 5e-25
Identities = 88/329 (26%), Positives = 152/329 (45%), Gaps = 26/329 (7%)
Query: 15 ISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS--RE 72
+S++ ++ E ++G+G +G V +A +A+K++ S RE
Sbjct: 9 LSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDD--KDYALKQIEGTGISMSACRE 66
Query: 73 LEILRIADHPNVVKLE-YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLK 131
+ +LR HPNV+ L+ F +H L+ + + + + + K ++LP
Sbjct: 67 IALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRG 126
Query: 132 HVKLYAYQIARGMLYLHALGICHRDIKPSNVLV---DPQTGILKICDFGSAKKLESNQPS 188
VK YQI G+ YLHA + HRD+KP+N+LV P+ G +KI D G A+ S
Sbjct: 127 MVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKP 186
Query: 189 IS----YICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL----- 239
++ + + +YRAPEL++G YT IDIW +GC+ E+L + +F Q +
Sbjct: 187 LADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNP 246
Query: 240 ----QLHEITKLLG-PPDKRFIFFSNPSYNGPL---FSKPLFEGAPKARF-EKYFGYAGP 290
QL I ++G P DK + + L F + + ++ EK+
Sbjct: 247 YHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDS 306
Query: 291 DGVDLLMSVLVYEPERRASPRRILAHPFF 319
LL +L +P +R + + + P+F
Sbjct: 307 KAFHLLQKLLTMDPIKRITSEQAMQDPYF 335
>Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 629
Score = 112 bits (281), Expect = 7e-25
Identities = 105/352 (29%), Positives = 163/352 (45%), Gaps = 55/352 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYFYT 92
IG+G+FG VV+AY Q+ + IK A EL +L + + + +++Y+
Sbjct: 117 IGKGSFGQVVKAY-DHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDT-EMKYYIV 174
Query: 93 HISPTDHKLYQH---LAMECLP----EMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
H+ H ++++ L E L ++L+N R NL L A Q+ +L
Sbjct: 175 HLKR--HFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKL------AQQLCTALL 226
Query: 146 YLHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPEL 202
+L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE+
Sbjct: 227 FLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEV 284
Query: 203 IVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI------ 256
++G T Y ID+W LGC+L EM G+ +F G + Q++ I ++LG P +
Sbjct: 285 LLG-TPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKA 343
Query: 257 --FFSNPSYNGPLFSKPL-----FEGAPKARFEKYFGY--AGPDG--------------- 292
+F G + ++G R ++ G GP G
Sbjct: 344 RKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLR 403
Query: 293 -VDLLMSVLVYEPERRASPRRILAHPFFDDLRNE-RYFFPSGSSQPKHLPPL 342
DL++ +L YEP R SP L H FF +E P+GSS PL
Sbjct: 404 FQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPL 455
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 112 bits (281), Expect = 7e-25
Identities = 94/336 (27%), Positives = 161/336 (46%), Gaps = 51/336 (15%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
+IG+G +G V +A ++ A+K+V + E + RE++ILR H N+V
Sbjct: 316 QIGEGTYGQVYKAVNNLTGEQ----VALKRVRLENEKEGFPITAIREIKILRQLHHKNIV 371
Query: 86 KL-EYFYTHISPTDHK--------LYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLY 136
+L + IS + K +++++ + + + E++ + K+ + K
Sbjct: 372 RLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFK----- 426
Query: 137 AYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLES-NQPSISYICSR 195
Q+ G+ Y+H G HRDIK SN+LV+ + G LKI D G A+ E ++ + + +
Sbjct: 427 --QLLEGLAYIHNTGFLHRDIKCSNILVNNK-GELKIADLGLARLWEKESRLYTNRVITL 483
Query: 196 YYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRF 255
+YR PEL++G +Y ID+W GC+LGE+ K +F G+ QL I+K+ G P+
Sbjct: 484 WYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVD- 542
Query: 256 IFFSNPSYNGPLFSKPL------FEGAPKARFEKYFGYAGP-DGVDLLMSVLVYEPERRA 308
N P ++ + + + R + F + P + VDLL +L PE+R
Sbjct: 543 --------NWPELTELVGWNTFRMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRI 594
Query: 309 SPRRILAHPFFDDLRNERYFFPSGSSQPKHLPPLYD 344
S + L HP+ L + + QP LP D
Sbjct: 595 SAKEALNHPWIRSLEHT-------TVQPLKLPQHQD 623
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 112 bits (280), Expect = 9e-25
Identities = 89/310 (28%), Positives = 155/310 (49%), Gaps = 38/310 (12%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS-----RELEILRIADHP 82
++ +++G+G++ TV + + + A+K + Q E + RE +L+ H
Sbjct: 118 EKLEKLGEGSYATVYKGKSKVNGKL----VALKVIRLQEEEGTPFTAIREASLLKGLKHA 173
Query: 83 NVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIAR 142
N+V L + H T +++++ + M K+ L +VKL+ +Q+ R
Sbjct: 174 NIVLL-HDIIHTKETLTLVFEYVHTDLCQYM--------DKHPGGLHPDNVKLFLFQLLR 224
Query: 143 GMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRA 199
G+ Y+H I HRD+KP N+L+ TG LK+ DFG A+ + PS +Y + + +YR
Sbjct: 225 GLSYIHQRYILHRDLKPQNLLIS-DTGELKLADFGLARA--KSVPSHTYSNEVVTLWYRP 281
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL-QLHEITKLLGPPDKRFI-- 256
P++++G T+Y+T +D+WG+GC+ EM+ G A F G + + QL I +LG P++
Sbjct: 282 PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG 341
Query: 257 FFSNPSYNGPLF----SKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRR 312
S P + F SK L + K + + DL +L P+ R S +
Sbjct: 342 VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNH-------AEDLASKLLQCSPKNRLSAQA 394
Query: 313 ILAHPFFDDL 322
L+H +F DL
Sbjct: 395 ALSHEYFSDL 404
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 112 bits (280), Expect = 9e-25
Identities = 89/316 (28%), Positives = 151/316 (47%), Gaps = 30/316 (9%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS--RELEILRIADHPNVVKLEY 89
++G+G +G V +A + +A+K++ S RE+ +LR HPNV+ L+
Sbjct: 26 KVGRGTYGHVYKARRKDGKDE--KEYALKQIEGTGISMSACREIALLRELKHPNVIALQK 83
Query: 90 FYTHISPTDHK---LYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+ +S +D K L+ + + + + + K ++LP VK YQI G+ Y
Sbjct: 84 VF--LSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 147 LHALGICHRDIKPSNVLV---DPQTGILKICDFGSAKKLESNQPSIS----YICSRYYRA 199
LHA + HRD+KP+N+LV P+ G +KI D G A+ S ++ + + +YRA
Sbjct: 142 LHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRA 201
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLL---------QLHEITKLLG- 249
PEL++G YT IDIW +GC+ E+L + +F Q + QL I ++G
Sbjct: 202 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGF 261
Query: 250 PPDKRFIFFSN-PSYN--GPLFSKPLFEGAPKARF-EKYFGYAGPDGVDLLMSVLVYEPE 305
P DK + P Y F + + + ++ EK+ LL +L +P
Sbjct: 262 PADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPT 321
Query: 306 RRASPRRILAHPFFDD 321
+R + + L P+F +
Sbjct: 322 KRITSEQALQDPYFQE 337
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 112 bits (279), Expect = 1e-24
Identities = 94/307 (30%), Positives = 148/307 (47%), Gaps = 34/307 (11%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
+IGQG FG V +A QK A+KKV + E + RE++IL++ H NVV
Sbjct: 24 KIGQGTFGEVFKARHRKTGQK----VALKKVLMENEKEGFPITALREIKILQLLKHENVV 79
Query: 86 KL-EYFYTHISPTDH-----KLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQ 139
L E T SP + L L +L N ++++ L +K
Sbjct: 80 NLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFT-------LSEIKRVMQM 132
Query: 140 IARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKL---ESNQPS--ISYICS 194
+ G+ Y+H I HRD+K +NVL+ + G+LK+ DFG A+ +++QP+ + + +
Sbjct: 133 LLNGLYYIHRNKILHRDMKAANVLIT-RDGVLKLADFGLARAFSLAKNSQPNRYTNRVVT 191
Query: 195 RYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKR 254
+YR PEL++G Y ID+WG GC++ EM + QG+ QL I++L G
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPE 251
Query: 255 FIFFSNPSYNGPLFSK-PLFEGAPKARFEKYFGYA-GPDGVDLLMSVLVYEPERRASPRR 312
+ N N L+ K L +G + ++ Y P +DL+ +LV +P +R
Sbjct: 252 --VWPNVD-NYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDD 308
Query: 313 ILAHPFF 319
L H FF
Sbjct: 309 ALNHDFF 315
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 112 bits (279), Expect = 1e-24
Identities = 86/303 (28%), Positives = 139/303 (45%), Gaps = 36/303 (11%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV------PAQTEYKSRELEILRIADHPNVV 85
++G+G++G V + Q AIKK P + RE+ +L+ H N+V
Sbjct: 9 KLGEGSYGVVYKCKNRDTGQI----VAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLV 64
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
L + + KL HL E + +E+ +KN + + +K YQ+ +
Sbjct: 65 GL----IEVFKRNRKL--HLVFELCDRTVLHEL---EKNPHGVNDELIKKIIYQLLEALK 115
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVG 205
+ H+ HRD+KP N+ + + K+ DFG A+ + + + Y+ +R+YR+PEL+VG
Sbjct: 116 FCHSHKCIHRDVKPENIFLTRNDQV-KLGDFGFARIINTTEMYTDYVATRWYRSPELLVG 174
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI-------FF 258
QY +DIW +GCV E+L G+A++ G + QL+ I K LG R I FF
Sbjct: 175 DVQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPRHISIFRTNQFF 234
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
S P +PL P A + +D L P+RR S ++ H
Sbjct: 235 FGLSIPEPEHLEPLPSKLPNASSAQ---------LDFLQKCFEMSPDRRFSCSELMLHGI 285
Query: 319 FDD 321
F +
Sbjct: 286 FSN 288
>Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 763
Score = 111 bits (278), Expect = 1e-24
Identities = 99/333 (29%), Positives = 162/333 (47%), Gaps = 52/333 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QTEYKSRELEILRIADHPNVVKLEY 89
IG+G+FG VV+AY + Q+W+ IK A Q + + R LE++ D +++Y
Sbjct: 165 IGKGSFGQVVKAYDRVE-QEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHD----TEMKY 219
Query: 90 FYTHISPTDHKLYQ-HLAMECLPEMLQNEILRYKKNN--LELPLKHVKLYAYQIARGMLY 146
+ H+ H +++ HL + + EML + +N + L + +A Q+ +L+
Sbjct: 220 YIVHLKR--HFMFRNHLCL--VFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLF 275
Query: 147 LHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE++
Sbjct: 276 LATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVL 333
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI------- 256
+G Y ID+W LGC+L EM G+ +F G + Q+++I ++LG P +
Sbjct: 334 LGMP-YDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKAR 392
Query: 257 -FFS---------NPSYNGPLFSKP-----------LFEGAPKARFEKYFGYAGPDGV-- 293
FF + +G KP + G P R G+ D +
Sbjct: 393 KFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKF 452
Query: 294 -DLLMSVLVYEPERRASPRRILAHPFFDDLRNE 325
DL++ +L Y+P+ R P L H FF +E
Sbjct: 453 KDLILRMLDYDPKTRIQPYYALQHSFFKKTADE 485
>Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 529
Score = 111 bits (278), Expect = 1e-24
Identities = 99/333 (29%), Positives = 162/333 (47%), Gaps = 52/333 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QTEYKSRELEILRIADHPNVVKLEY 89
IG+G+FG VV+AY + Q+W+ IK A Q + + R LE++ D +++Y
Sbjct: 165 IGKGSFGQVVKAYDRVE-QEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHD----TEMKY 219
Query: 90 FYTHISPTDHKLYQ-HLAMECLPEMLQNEILRYKKNN--LELPLKHVKLYAYQIARGMLY 146
+ H+ H +++ HL + + EML + +N + L + +A Q+ +L+
Sbjct: 220 YIVHLKR--HFMFRNHLCL--VFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLF 275
Query: 147 LHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE++
Sbjct: 276 LATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVL 333
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI------- 256
+G Y ID+W LGC+L EM G+ +F G + Q+++I ++LG P +
Sbjct: 334 LGMP-YDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKAR 392
Query: 257 -FFS---------NPSYNGPLFSKP-----------LFEGAPKARFEKYFGYAGPDGV-- 293
FF + +G KP + G P R G+ D +
Sbjct: 393 KFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKF 452
Query: 294 -DLLMSVLVYEPERRASPRRILAHPFFDDLRNE 325
DL++ +L Y+P+ R P L H FF +E
Sbjct: 453 KDLILRMLDYDPKTRIQPYYALQHSFFKKTADE 485
>Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 540
Score = 111 bits (278), Expect = 1e-24
Identities = 99/333 (29%), Positives = 162/333 (47%), Gaps = 52/333 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QTEYKSRELEILRIADHPNVVKLEY 89
IG+G+FG VV+AY + Q+W+ IK A Q + + R LE++ D +++Y
Sbjct: 165 IGKGSFGQVVKAYDRVE-QEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHD----TEMKY 219
Query: 90 FYTHISPTDHKLYQ-HLAMECLPEMLQNEILRYKKNN--LELPLKHVKLYAYQIARGMLY 146
+ H+ H +++ HL + + EML + +N + L + +A Q+ +L+
Sbjct: 220 YIVHLKR--HFMFRNHLCL--VFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLF 275
Query: 147 LHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE++
Sbjct: 276 LATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVL 333
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI------- 256
+G Y ID+W LGC+L EM G+ +F G + Q+++I ++LG P +
Sbjct: 334 LGMP-YDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKAR 392
Query: 257 -FFS---------NPSYNGPLFSKP-----------LFEGAPKARFEKYFGYAGPDGV-- 293
FF + +G KP + G P R G+ D +
Sbjct: 393 KFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKF 452
Query: 294 -DLLMSVLVYEPERRASPRRILAHPFFDDLRNE 325
DL++ +L Y+P+ R P L H FF +E
Sbjct: 453 KDLILRMLDYDPKTRIQPYYALQHSFFKKTADE 485
>Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 754
Score = 111 bits (278), Expect = 1e-24
Identities = 99/333 (29%), Positives = 162/333 (47%), Gaps = 52/333 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QTEYKSRELEILRIADHPNVVKLEY 89
IG+G+FG VV+AY + Q+W+ IK A Q + + R LE++ D +++Y
Sbjct: 156 IGKGSFGQVVKAYDRVE-QEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHD----TEMKY 210
Query: 90 FYTHISPTDHKLYQ-HLAMECLPEMLQNEILRYKKNN--LELPLKHVKLYAYQIARGMLY 146
+ H+ H +++ HL + + EML + +N + L + +A Q+ +L+
Sbjct: 211 YIVHLKR--HFMFRNHLCL--VFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLF 266
Query: 147 LHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE++
Sbjct: 267 LATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVL 324
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI------- 256
+G Y ID+W LGC+L EM G+ +F G + Q+++I ++LG P +
Sbjct: 325 LGMP-YDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKAR 383
Query: 257 -FFS---------NPSYNGPLFSKP-----------LFEGAPKARFEKYFGYAGPDGV-- 293
FF + +G KP + G P R G+ D +
Sbjct: 384 KFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKF 443
Query: 294 -DLLMSVLVYEPERRASPRRILAHPFFDDLRNE 325
DL++ +L Y+P+ R P L H FF +E
Sbjct: 444 KDLILRMLDYDPKTRIQPYYALQHSFFKKTADE 476
>Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 584
Score = 111 bits (278), Expect = 1e-24
Identities = 99/333 (29%), Positives = 162/333 (47%), Gaps = 52/333 (15%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPA---QTEYKSRELEILRIADHPNVVKLEY 89
IG+G+FG VV+AY + Q+W+ IK A Q + + R LE++ D +++Y
Sbjct: 165 IGKGSFGQVVKAYDRVE-QEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHD----TEMKY 219
Query: 90 FYTHISPTDHKLYQ-HLAMECLPEMLQNEILRYKKNN--LELPLKHVKLYAYQIARGMLY 146
+ H+ H +++ HL + + EML + +N + L + +A Q+ +L+
Sbjct: 220 YIVHLKR--HFMFRNHLCL--VFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLF 275
Query: 147 LHA--LGICHRDIKPSNVLV-DPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELI 203
L L I H D+KP N+L+ +P+ +KI DFGS+ +L Q YI SR+YR+PE++
Sbjct: 276 LATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVL 333
Query: 204 VGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI------- 256
+G Y ID+W LGC+L EM G+ +F G + Q+++I ++LG P +
Sbjct: 334 LGMP-YDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKAR 392
Query: 257 -FFS---------NPSYNGPLFSKP-----------LFEGAPKARFEKYFGYAGPDGV-- 293
FF + +G KP + G P R G+ D +
Sbjct: 393 KFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKF 452
Query: 294 -DLLMSVLVYEPERRASPRRILAHPFFDDLRNE 325
DL++ +L Y+P+ R P L H FF +E
Sbjct: 453 KDLILRMLDYDPKTRIQPYYALQHSFFKKTADE 485
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 111 bits (278), Expect = 1e-24
Identities = 94/303 (31%), Positives = 142/303 (46%), Gaps = 25/303 (8%)
Query: 32 RIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNVV 85
+IGQG FG V +A N+K++ A+KKV E + RE+ IL++ H NVV
Sbjct: 55 KIGQGTFGEVFKAREKKGNKKFV---AMKKVLMDNEKEGFPITALREIRILQLLKHENVV 111
Query: 86 KL-EYFYTHISPTD-HKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARG 143
L E T + T+ ++ +L + L + N++ L +K Q+ G
Sbjct: 112 NLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLL---SNMNVKFSLGEIKKVMQQLLNG 168
Query: 144 MLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAK-----KLESNQPSISYICSRYYR 198
+ Y+H+ I HRD+K +NVL+ GILK+ DFG A+ K ES + + + +YR
Sbjct: 169 LYYIHSNKILHRDMKAANVLITKH-GILKLADFGLARAFSIPKNESKNRYTNRVVTLWYR 227
Query: 199 APELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG--PPDKRFI 256
PEL++G Y +D+WG GC++ EM + QG+ QL I++L G PD
Sbjct: 228 PPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPG 287
Query: 257 FFSNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAH 316
Y K + K R Y G DLL +L +P++R L H
Sbjct: 288 VEELELYKSIELPKNQ-KRRVKERLRPY--VKDQTGCDLLDKLLTLDPKKRIDADTALNH 344
Query: 317 PFF 319
FF
Sbjct: 345 DFF 347
>At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 432
Score = 110 bits (276), Expect = 2e-24
Identities = 80/302 (26%), Positives = 149/302 (48%), Gaps = 23/302 (7%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILR-IADHPNVVKL-E 88
+++G+G + V + DN+K + I K P + + RE++IL+ + PN+VKL +
Sbjct: 136 RKVGRGKYSEVFEGIHATDNEKCV--IKILK-PVKKKKIKREIKILQNLCGGPNIVKLLD 192
Query: 89 YFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLH 148
S T +++H+ + ++L + Y V+ Y +++ + + + H
Sbjct: 193 IVRDQQSKTPSLIFEHVNNKDF-KVLYPTLSDYD----------VRYYIFELLKALDFCH 241
Query: 149 ALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGCTQ 208
+ GI HRD+KP NV++D + L++ D+G A+ + + SRY++ PEL+V
Sbjct: 242 SRGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQD 301
Query: 209 YTTKIDIWGLGCVLGEMLLGK-AVFQGHQPLLQLHEITKLLGPPD-----KRFIFFSNPS 262
Y +D+W LGC+ M+ K F GH QL +I K+LG + ++ +P+
Sbjct: 302 YDYSLDLWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGTDELNAYLNKYRIELDPN 361
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDDL 322
L + + K + A P+ VD + +L Y+ + R + + +AHP+F +
Sbjct: 362 LTS-LVGRHSRKPWTKFINSENQHLAVPEAVDFVDKLLRYDHQERPTAKEAMAHPYFYPI 420
Query: 323 RN 324
RN
Sbjct: 421 RN 422
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 110 bits (275), Expect = 3e-24
Identities = 77/226 (34%), Positives = 113/226 (49%), Gaps = 38/226 (16%)
Query: 34 GQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYK---SRELEILRIADHPNVVKLEYF 90
G+GAFG VV A T +++ AIK++ K +RE+ LR H N++KL
Sbjct: 15 GRGAFGLVVIARDTLTSKR----VAIKRIMVPNVSKVSLAREISCLRNLHHRNILKL--- 67
Query: 91 YTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHAL 150
++C P I+ E+P Y QI G+ YLH+
Sbjct: 68 ----------------LDCFPSADLMSIVTE-----EVPYTW---YYTQILSGIAYLHSK 103
Query: 151 GICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY---ICSRYYRAPELIVGCT 207
I HRDIKP N+LV + ++KI DFG A P+ Y + +R+YRAPEL+ G
Sbjct: 104 EIMHRDIKPENILVTSRN-VVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLFGSK 162
Query: 208 QYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDK 253
+Y +DIW +GC+L E++ GK +F G L Q+ I +LG P++
Sbjct: 163 KYKPDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNE 208
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 110 bits (275), Expect = 3e-24
Identities = 83/299 (27%), Positives = 146/299 (48%), Gaps = 26/299 (8%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADHPNV 84
++IG+G +GTV + N+ + A+K+V + + RE+ +L+ H N+
Sbjct: 8 EKIGEGTYGTVFKGR----NRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNI 63
Query: 85 VKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
V+L + +D KL L E + L+ + N E+ + + + Q+ RG+
Sbjct: 64 VRL----IDVLHSDKKLT--LVFEHCDQDLKKY---FDSLNGEIDMAVCRSFMLQLLRGL 114
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRAPELI 203
+ H+ + HRD+KP N+L++ + G LK+ DFG A+ S + + +YR P+++
Sbjct: 115 AFCHSHNVLHRDLKPQNLLIN-KNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVL 173
Query: 204 VGCTQYTTKIDIWGLGCVLGEML-LGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPS 262
G YTT ID+W GC+L E+ G+ +F G L QL +I ++LG P++ + S
Sbjct: 174 FGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNED--SWPGVS 231
Query: 263 YNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFFDD 321
+ + P F + + G DLL +L+ P +R S + HP+F D
Sbjct: 232 HLSDYVALPSFPAI--TSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
>CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 948
Score = 110 bits (274), Expect = 4e-24
Identities = 96/344 (27%), Positives = 168/344 (47%), Gaps = 49/344 (14%)
Query: 14 VISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVP-AQTEYKSRE 72
++ N + ++ +G+G+FG V +AY T + ++ AIK + +T + +
Sbjct: 381 ILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEE----VAIKIIKNKKTFFDQAQ 436
Query: 73 LEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLP-EMLQNEILRYKKNNL--ELP 129
+EI + + N + Y ++ H + H A CL E+L + KN +
Sbjct: 437 IEI-HLLELTNAHDKDNKYNIVTLKGH--FVHRAHLCLVFELLSYNLYDLLKNTSFRGVS 493
Query: 130 LKHVKLYAYQIARGMLYLHA--LGICHRDIKPSNVL-VDPQTGILKICDFGSAKKLESNQ 186
L + +A Q+ + +L+L + L I H D+KP NVL V+ + +++ DFGS+ ++
Sbjct: 494 LNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSS--CQTGH 551
Query: 187 PSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITK 246
YI SR+YR+PE+++G Y TKID+W LGC+L EM G+ +F G + Q+ +I +
Sbjct: 552 RIYQYIQSRFYRSPEVLLGIA-YDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVE 610
Query: 247 LLGPPDKRFI-------FFSNPSYNGPLFSKPLFEG------APKAR-FEKYFGY--AGP 290
+LG P K + + + + +G + K +G AP AR + G GP
Sbjct: 611 VLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGP 670
Query: 291 DG----------------VDLLMSVLVYEPERRASPRRILAHPF 318
G DL+ +L ++P++R SP ++ HPF
Sbjct: 671 GGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPF 714
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 109 bits (272), Expect = 7e-24
Identities = 82/322 (25%), Positives = 146/322 (44%), Gaps = 35/322 (10%)
Query: 33 IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELE-ILRIADHPNVV 85
I +G +G V + T ++ A+K+ + E + RE+ +L+ H N+V
Sbjct: 405 IAEGTYGEVFRGKNTRTDEV----VALKRFKMEKEKEGFPITALREINMLLKAGAHENIV 460
Query: 86 KLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGML 145
++ + T+ ++AME + +++ I + + N K Q+ G+
Sbjct: 461 NVKEILVGSTKTE----VYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIE 516
Query: 146 YLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKK------LESNQPSISYICSRYYRA 199
++H L I HRD+K SN+L+ +GILKI DFG A++ +E + + +YR+
Sbjct: 517 HMHKLWILHRDLKTSNLLIS-HSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRS 575
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFS 259
PEL++ Y+T +D+W +GC++ E ++ K +FQG Q+H+I +++G P ++
Sbjct: 576 PELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDI 635
Query: 260 NPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPFF 319
+ P + R K G DLL +L P R + L H +F
Sbjct: 636 KELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWF 695
Query: 320 DDLRNERYFFPSGSSQPKHLPP 341
S PK +PP
Sbjct: 696 -------------SEHPKAVPP 704
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 109 bits (272), Expect = 7e-24
Identities = 77/301 (25%), Positives = 143/301 (46%), Gaps = 31/301 (10%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKV--PAQTEYKSRELEILR-IADHPNVVKL 87
+++G+G + V +A +K + K+ P + + RE++IL + N++ L
Sbjct: 41 RKLGRGKYSEVFEAINITTTEK-----CVVKILKPVKKKKIKREIKILENLRGGTNIITL 95
Query: 88 -EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLY 146
+S T +++H+ ++ Q L ++ Y +++ + + Y
Sbjct: 96 LAVVKDPVSRTPALIFEHVNNTDFKQLYQT-----------LTDYEIRYYLFELLKALDY 144
Query: 147 LHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVGC 206
H++GI HRD+KP NV++D + L++ D+G A+ Q + SRY++ PEL+V
Sbjct: 145 CHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDY 204
Query: 207 TQYTTKIDIWGLGCVLGEMLLGK-AVFQGHQPLLQLHEITKLLGPPDKRFIFFSNPSYNG 265
Y +D+W LGC+L M+ K F GH QL I K+LG + ++ YN
Sbjct: 205 QMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEE---LYAYLDKYNI 261
Query: 266 PLFSK--PLFEGAPKARFEKYF-----GYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
L + + + + R+E++ P+ +D L +L Y+ R + R +AHP+
Sbjct: 262 DLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPY 321
Query: 319 F 319
F
Sbjct: 322 F 322
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 108 bits (270), Expect = 1e-23
Identities = 98/319 (30%), Positives = 151/319 (46%), Gaps = 41/319 (12%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYF 90
K IG+G+FG VV+AY + K A+K V + + + E +RI +H +
Sbjct: 226 KVIGKGSFGQVVKAY----DHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNT 281
Query: 91 YTHISPTDHKLYQ-HLAM--ECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
I ++ ++ H+ M E L L I + K LPL V+ +A+ I + + L
Sbjct: 282 MNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPL--VRKFAHSILQCLDAL 339
Query: 148 HALGICHRDIKPSNVLVDPQ--TGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVG 205
H I H D+KP N+L+ Q +GI K+ DFGS+ +Q +YI SR+YRAPE+I+G
Sbjct: 340 HKNRIIHCDLKPENILLKQQGRSGI-KVIDFGSS--CYEHQRVYTYIQSRFYRAPEVILG 396
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--------F 257
+Y ID+W LGC+L E+L G + G QL + +LLG P ++ + F
Sbjct: 397 A-RYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNF 455
Query: 258 FSNPSY----------------NGPLFSKPLFEGAPKAR--FEKYFGYAGPDGVDLLMSV 299
S+ Y NG + G P++R G P +D L
Sbjct: 456 VSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQC 515
Query: 300 LVYEPERRASPRRILAHPF 318
L ++P R +P + L HP+
Sbjct: 516 LEWDPAVRMTPGQALRHPW 534
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 108 bits (270), Expect = 1e-23
Identities = 98/319 (30%), Positives = 151/319 (46%), Gaps = 41/319 (12%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSRELEILRIADHPNVVKLEYF 90
K IG+G+FG VV+AY + K A+K V + + + E +RI +H +
Sbjct: 153 KVIGKGSFGQVVKAY----DHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNT 208
Query: 91 YTHISPTDHKLYQ-HLAM--ECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYL 147
I ++ ++ H+ M E L L I + K LPL V+ +A+ I + + L
Sbjct: 209 MNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPL--VRKFAHSILQCLDAL 266
Query: 148 HALGICHRDIKPSNVLVDPQ--TGILKICDFGSAKKLESNQPSISYICSRYYRAPELIVG 205
H I H D+KP N+L+ Q +GI K+ DFGS+ +Q +YI SR+YRAPE+I+G
Sbjct: 267 HKNRIIHCDLKPENILLKQQGRSGI-KVIDFGSS--CYEHQRVYTYIQSRFYRAPEVILG 323
Query: 206 CTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFI--------F 257
+Y ID+W LGC+L E+L G + G QL + +LLG P ++ + F
Sbjct: 324 A-RYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNF 382
Query: 258 FSNPSY----------------NGPLFSKPLFEGAPKAR--FEKYFGYAGPDGVDLLMSV 299
S+ Y NG + G P++R G P +D L
Sbjct: 383 VSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQC 442
Query: 300 LVYEPERRASPRRILAHPF 318
L ++P R +P + L HP+
Sbjct: 443 LEWDPAVRMTPGQALRHPW 461
>Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1198
Score = 108 bits (270), Expect = 1e-23
Identities = 81/251 (32%), Positives = 133/251 (52%), Gaps = 22/251 (8%)
Query: 8 EYVAHDVISNKSNVKREMLVKEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTE 67
+ V H+V+ + +N V E+ +G+G FG VV+ + N+ AIK + +
Sbjct: 185 QLVQHEVLCSMTNTYE---VLEF--LGRGTFGQVVKCWKRGTNEI----VAIKILKNRPS 235
Query: 68 Y-KSRELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLP-EMLQNEILRYKKNN 125
Y + ++E+ +A +Y + ++ +QH CL EML+ + + K N
Sbjct: 236 YARQGQIEVSILARLSTESADDYNFVRA----YECFQHKNHTCLVFEMLEQNLYDFLKQN 291
Query: 126 L--ELPLKHVKLYAYQIARGMLYLHALGICHRDIKPSNV-LVDP--QTGILKICDFGSAK 180
LPLK+++ Q+A ++ L +LG+ H D+KP N+ LVDP Q +K+ DFGSA
Sbjct: 292 KFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSAS 351
Query: 181 KLESNQPSISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQ 240
+ S +Y+ SRYYRAPE+I+G + ID+W LGCV+ E+ LG ++ G Q
Sbjct: 352 HV-SKAVCSTYLQSRYYRAPEIILG-LPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQ 409
Query: 241 LHEITKLLGPP 251
+ I++ G P
Sbjct: 410 IRYISQTQGLP 420
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 108 bits (269), Expect = 2e-23
Identities = 80/306 (26%), Positives = 145/306 (47%), Gaps = 41/306 (13%)
Query: 31 KRIGQGAFGTVVQAYLTPDNQ----KWLGPFAIKKVPAQTEYKSRELEILR-IADHPNVV 85
+++G+G + V +A +N+ K L P KK+ RE++IL + N++
Sbjct: 44 RKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKI-------KREVKILENLRGGTNII 96
Query: 86 KL-EYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGM 144
KL + +S T +++++ ++ Q L ++ Y Y++ + +
Sbjct: 97 KLIDTVKDPVSKTPALVFEYINNTDFKQLYQI-----------LTDFDIRFYMYELLKAL 145
Query: 145 LYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISYICSRYYRAPELIV 204
Y H+ GI HRD+KP NV++D Q L++ D+G A+ Q + SRY++ PEL+V
Sbjct: 146 DYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLV 205
Query: 205 GCTQYTTKIDIWGLGCVLGEMLLGK-AVFQGHQPLLQLHEITKLLGPPD-----KRFIFF 258
Y +D+W LGC+L M+ + F G QL I K+LG + K++
Sbjct: 206 DYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHID 265
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYF-----GYAGPDGVDLLMSVLVYEPERRASPRRI 313
+P +N L + R+E + P+ +DLL +L Y+ ++R + +
Sbjct: 266 LDPHFNDILGQH------SRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEA 319
Query: 314 LAHPFF 319
+ HP+F
Sbjct: 320 MEHPYF 325
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 107 bits (267), Expect = 3e-23
Identities = 83/316 (26%), Positives = 148/316 (46%), Gaps = 48/316 (15%)
Query: 43 QAYLTPDNQKWLGPFAIK----KVPAQTEY-KSRELEILRIADHPNVVKLEYFYTHISPT 97
Q Y+T K G AIK K+ +Y + RE++ + +A N ++ F I
Sbjct: 84 QNYIT----KTQGVVAIKTMMTKLHTLQDYTRVREIKFI-LAIPANDHLIQIFEVFIDSE 138
Query: 98 DHKLYQHLAMECLPEMLQNEILRYKKNNLELPLKHVKLYAYQIARGMLYLHALGICHRDI 157
+++L H+ MEC+ + L + ++ +P +K QI G+ ++H HRD+
Sbjct: 139 NYQL--HIVMECMEQNLYQMMKHRRRRVFSIP--SLKSILSQILAGLKHIHEHNFFHRDL 194
Query: 158 KPSNVLVDPQTG----------------ILKICDFGSAKKLESNQPSISYICSRYYRAPE 201
KP N+L+ P T ++K+ DFG A+ +E+ P +Y+ +R+YR+PE
Sbjct: 195 KPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPE 254
Query: 202 LIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNP 261
+++ Y+ +DIW GCV E+ + +A+F G + Q+ +I ++LG P KR F +
Sbjct: 255 ILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTN 314
Query: 262 SYNGP-----------LFSK-----PLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPE 305
P L K P EG+ + D +++ L ++P
Sbjct: 315 HITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLS--DLSEVVKKCLRWDPN 372
Query: 306 RRASPRRILAHPFFDD 321
RA+ + + PFF++
Sbjct: 373 ERATAQELCEMPFFEN 388
>CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 398
Score = 107 bits (267), Expect = 3e-23
Identities = 99/337 (29%), Positives = 151/337 (44%), Gaps = 66/337 (19%)
Query: 71 RELEILRIADHPNVVKLEYFYTHISPTDHKL----------YQHLAMECLPEMLQNEILR 120
REL + + NVVK+ Y+ +P ++ L Y H M+ L NE
Sbjct: 68 RELNCMLNIEDDNVVKM---YSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGH 124
Query: 121 YKKNNLELPLKHVKLYAYQIARGMLYLHALGICHR--------------DIKPSNVLVDP 166
+ VK + I RG+ YLHA+ I HR D+KP N+L++
Sbjct: 125 ----------RTVKSIFFDICRGVQYLHAMRISHRYFISKLVYFVTERQDLKPENILMN- 173
Query: 167 QTGILKICDFGSAKKLE--SNQPSISYICSRYYRAPELIVGCTQYT-TKIDIWGLGCVLG 223
Q G +K+CDFG + K + SN P YI R+YRAPE+I T T +DIW LGC+L
Sbjct: 174 QEGDVKLCDFGHSNKEDPTSNTP---YIVQRFYRAPEIICETTDNNKTNVDIWSLGCILA 230
Query: 224 EMLLGKAVFQGHQPLLQLHEITKLLGPPDKRFIFFSNP-------SYNGPLFSKPL--FE 274
E+L G +F+G + Q + + LG F N YN + P+ +
Sbjct: 231 ELLTGHVLFRGKDHIDQFILMVQFLGNAGPSFYSQMNEHARNFLLRYNLDQYQAPINFYS 290
Query: 275 GAPKARFEKYFGYAGPD---GVDLLMSVLVYEPERRASPRRILAHPFFDDLRNERYFFPS 331
P F+ + + DLL +LV P+ R + + +L+HP+ ++ E +
Sbjct: 291 RFPDTVFQGVLQFEPKECDMSRDLLFRMLVINPDDRLNIQMVLSHPYLREIWGE---IVA 347
Query: 332 GSSQPKHLPP--LYDFSDFE-----LQVIGDLFPKIQ 361
P+ PP L F DF+ L + ++F KI+
Sbjct: 348 EDVIPEPQPPNELLRFFDFQPYSSPLDMREEIFQKIK 384
>CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 821
Score = 107 bits (267), Expect = 3e-23
Identities = 77/244 (31%), Positives = 122/244 (49%), Gaps = 22/244 (9%)
Query: 21 VKREMLVKEYKR-------IGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKSREL 73
+K E+L Y +G+G FG VV+A+ + + +KK P+ E+
Sbjct: 109 IKNEVLCSPYGNQYEVLEFLGKGTFGQVVKAW-KKGTSEIVAIKILKKHPSYARQGQIEV 167
Query: 74 EILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLP-EMLQNEILRYKKNN--LELPL 130
IL + N + + + + H + CL EML+ + + K N + LPL
Sbjct: 168 SILSRLSNENSEEFNFVRAF------ECFNHKSHTCLVFEMLEQNLYDFLKQNKFMPLPL 221
Query: 131 KHVKLYAYQIARGMLYLHALGICHRDIKPSNV-LVDPQTG--ILKICDFGSAKKLESNQP 187
++ +Q+ +L L +LG+ H D+KP N+ LVDPQ +K+ DFGSA S
Sbjct: 222 NAIRPILFQVLTALLKLKSLGLIHADLKPENIMLVDPQQQPYRVKVIDFGSASH-RSKAV 280
Query: 188 SISYICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKL 247
+ +Y+ SRYYRAPE+I+G + ID+W LGCV+ E+ LG ++ G Q+ I +
Sbjct: 281 TNTYLQSRYYRAPEIILG-LPFNESIDMWSLGCVIAELFLGWPLYPGSSEYDQIRFIIQT 339
Query: 248 LGPP 251
G P
Sbjct: 340 QGLP 343
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 107 bits (266), Expect = 4e-23
Identities = 81/272 (29%), Positives = 133/272 (48%), Gaps = 17/272 (6%)
Query: 71 RELEILRIADHPNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKNNLELPL 130
RE+E L H N+V+LE D +L ME + L+ + ++ L+ +
Sbjct: 120 REIESLSSIRHDNIVELEKVVVGKDLKD----VYLVMEFMEHDLKTLLDNMPEDFLQSEV 175
Query: 131 KHVKLYAYQIARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSIS 190
K + L Q+ ++H HRD+KPSN+L++ TG +K+ DFG A+ + + S++
Sbjct: 176 KTLML---QLLAATAFMHHHWYLHRDLKPSNLLMN-NTGEIKLADFGLARPVSEPKSSLT 231
Query: 191 -YICSRYYRAPELIVGCTQYTTKIDIWGLGCVLGEMLLGKAVFQGHQPLLQLHEITKLLG 249
+ + +YRAPEL++G Y +ID+W +GC+ EM+ +F G L QL++I LLG
Sbjct: 232 RLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLG 291
Query: 250 PPDKRFIFFSNPSY-NGPLFSKPLFEGAP-KARFEKYFGYAGPDGVDLLMSVLVYEPERR 307
P + P Y P +K P ++ + DLL +L P +R
Sbjct: 292 YPTRE----EWPQYFLLPYANKIKHPTVPTHSKIRTSIPNLTGNAYDLLNRLLSLNPAKR 347
Query: 308 ASPRRILAHPFFDDLRNER--YFFPSGSSQPK 337
S + L HP+F + + FFP+ S+ K
Sbjct: 348 ISAKEALEHPYFYESPRPKDPKFFPTFPSKAK 379
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 106 bits (265), Expect = 5e-23
Identities = 84/303 (27%), Positives = 145/303 (47%), Gaps = 28/303 (9%)
Query: 28 KEYKRIGQGAFGTVVQAYLTPDNQKWLGPFAIKKVPAQTEYKS------RELEILRIADH 81
++ ++IG+G +GTV +A N++ A+K+V + + RE+ +L+ H
Sbjct: 5 EKLEKIGEGTYGTVFKA----KNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 82 PNVVKLEYFYTHISPTDHKLYQHLAMECLPEMLQNEILRYKKN-NLELPLKHVKLYAYQI 140
N+V+L + +D KL + E ++ +Y + N +L + VK + +Q+
Sbjct: 61 KNIVRLH----DVLHSDKKL------TLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQL 110
Query: 141 ARGMLYLHALGICHRDIKPSNVLVDPQTGILKICDFGSAKKLESNQPSISY-ICSRYYRA 199
+G+ + H+ + HRD+KP N+L++ + G LK+ DFG A+ S + + +YR
Sbjct: 111 LKGLGFCHSRNVLHRDLKPQNLLIN-RNGELKLADFGLARAFGIPVRCYSAEVVTLWYRP 169
Query: 200 PELIVGCTQYTTKIDIWGLGCVLGEML-LGKAVFQGHQPLLQLHEITKLLGPPDKRFIFF 258
P+++ G Y+T ID+W GC+ E+ G+ +F G+ QL I +LLG P +
Sbjct: 170 PDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEE---- 225
Query: 259 SNPSYNGPLFSKPLFEGAPKARFEKYFGYAGPDGVDLLMSVLVYEPERRASPRRILAHPF 318
PS KP G DLL ++L P +R S L HP+
Sbjct: 226 QWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
Query: 319 FDD 321
F D
Sbjct: 286 FSD 288
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.142 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,656,803
Number of Sequences: 60738
Number of extensions: 1160970
Number of successful extensions: 7247
Number of sequences better than 1.0e-05: 1517
Number of HSP's better than 0.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 1256
Number of HSP's that attempted gapping in prelim test: 4156
Number of HSP's gapped (non-prelim): 1920
length of query: 365
length of database: 30,389,216
effective HSP length: 108
effective length of query: 257
effective length of database: 23,829,512
effective search space: 6124184584
effective search space used: 6124184584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)