ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1927 good S KOG2811 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1927 681586 682887 434
(434 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL125w [S] KOG2811 Uncharacterized conserved protein 292 8e-79
7298929 [S] KOG2811 Uncharacterized conserved protein 175 1e-43
Hs11024704 [S] KOG2811 Uncharacterized conserved protein 159 8e-39
SPAC1805.03c [S] KOG2811 Uncharacterized conserved protein 150 3e-36
CE22211 [S] KOG2811 Uncharacterized conserved protein 138 1e-32
At4g01880 [S] KOG2811 Uncharacterized conserved protein 100 6e-21
>YOL125w [S] KOG2811 Uncharacterized conserved protein
Length = 476
Score = 292 bits (747), Expect = 8e-79
Identities = 189/480 (39%), Positives = 267/480 (55%), Gaps = 81/480 (16%)
Query: 15 AERLQCEFFLVKKKRQCGMTRRAGSQFCSEH--------------------STDSDRVPC 54
+ERLQCE+F+ KKKR+CGMTR + + +CSEH + +RVPC
Sbjct: 16 SERLQCEYFMEKKKRRCGMTRSSQNLYCSEHLNLMKKAANSQVHNKNGSEAEKERERVPC 75
Query: 55 PLDPSHTVCLSKMRVHMRKCNKFRHDVSYQAKQREIPWFKEGLNSISNGKSDSKPAD--- 111
PLDP+HTV +++ H++KCNK + K P+++ G N + S S D
Sbjct: 76 PLDPNHTVWADQLKKHLKKCNKTKLSHLNDDK----PYYEPGYNGENGLLSSSVKIDITA 131
Query: 112 ETLVKSVSLIQKIFQNEFGDEPPLPLIEKQNELLERTERYKTLVNRKHARQQSSLIQHLK 171
E LV+S+ L+ K+F+ E DE LPL + N+L+ + N KHA QQSSLI++L
Sbjct: 132 EHLVQSIELLYKVFEGESMDE--LPLRQLNNKLMSLKRFPQLPSNTKHAVQQSSLIENLV 189
Query: 172 ESKLWPSLESCAVNKTLEYIELGCGRAEFSRYVN--IATNLDQKEHSHEKPEYKAVAPSF 229
++ + ES L +IE GCGRAEFSRYV+ + T L H + F
Sbjct: 190 DAGAFERPES------LNFIEFGCGRAEFSRYVSLYLLTQLTSLPAEHSGSN----SNEF 239
Query: 230 TLIDRASQRLRFDNKFSSDIGTEVQ------------IRREKIDIKDLRLDAVLH----D 273
LIDRA+ R++FD K D +E++ I+R KIDI+DL++D +L D
Sbjct: 240 VLIDRATNRMKFDKKIKDDF-SEIKSNSPSKPISCPSIKRIKIDIRDLKMDPILKSTPGD 298
Query: 274 ASQYVAISKHLCGVATDLSLRCLLNS--------DKCKANLRGILIAMCCRHVCQSSEYV 325
QYV ISKHLCGVATDL+LRC+ NS + C L+ I IAMCCRHVC +YV
Sbjct: 299 DIQYVCISKHLCGVATDLTLRCIGNSSILHGDDNNGCNPKLKAICIAMCCRHVCDYGDYV 358
Query: 326 NQEYIKGLL-KRQTDGS-MAYSEFFQCLKKFCSYCTCGLRPD---------MDPNSGSED 374
N+ Y+ L+ K + GS + Y FF+ L K CS+ TCG +P ++ G+E
Sbjct: 359 NRSYVTSLVEKYRAHGSILTYETFFRVLTKLCSWGTCGRKPGTAITDIVNVVESFEGAEP 418
Query: 375 HITKLTHNERQRIGHMARRIIDEGRAQFLQSK--GFETVLFKYTDSAVTLEDTALLALRK 432
+ +T ER+ IG MARR+IDEGR +++ K F L +Y +S V+LE+ A+L +K
Sbjct: 419 Y--TITIKERENIGLMARRVIDEGRLVYVKEKFTEFNAELIRYVESDVSLENVAMLVYKK 476
>7298929 [S] KOG2811 Uncharacterized conserved protein
Length = 434
Score = 175 bits (443), Expect = 1e-43
Identities = 138/451 (30%), Positives = 217/451 (47%), Gaps = 84/451 (18%)
Query: 20 CEFFLVKKKRQCGMTRRAGSQFCSEHSTDS----------------DRVPCPLDPSHTVC 63
C +++++KKR+C MT GS+FC H++ + +R+PCPLD HTV
Sbjct: 14 CSYWVLRKKRRCKMTANKGSEFCGAHASSAATTATCDEKAREDSFQERIPCPLDHKHTVF 73
Query: 64 LSKMRVHMRKCNKFRHDVSYQAKQREIPWFKEGLNSISNGKSDSKPADETLVKSVSLIQK 123
K+ H+ CN + ++ +P+ +G+NS N K DE L K +
Sbjct: 74 KRKLAKHLTICNA-------RDQESSLPYIVKGVNSGDN----LKETDEDLNK----FNQ 118
Query: 124 IFQNEFGDEPPLPLIEKQNELLERT------------ERYKTLVNRKHARQQSSLIQHLK 171
I +E DE LI+K L ++ E K ++RK Q++ L Q +
Sbjct: 119 IKLHELADEEFYSLIDKVKNLYDKHINSSIQELQLEHESLKEELSRKDYGQET-LRQLTQ 177
Query: 172 ESKLWPSLE-SCAVNKTLEYIELGCGRAEFSRYVNIATNLDQKEHSHEKPEYKAVAPSFT 230
+ L LE + YIE G G+ + + + +AT L +++ SH +
Sbjct: 178 TTSLLGILEHDHQLMDHTSYIEFGAGKGQLAYF--LATVLQEQKLSHSQ---------VV 226
Query: 231 LIDRASQRLRFDNKFSSDIGTEVQIRREKIDIKDLRLDAV--LHDASQYVAISKHLCGVA 288
LIDR S R + DNK ++ EV ++R + DI DL+L A+ L + VA SKHLCG A
Sbjct: 227 LIDRMSLRHKKDNKLAN---REV-VQRIRADIADLKLSALPELKKTQRTVAFSKHLCGAA 282
Query: 289 TDLSLRCLLNSDKCKANLRGILIAMCCRHVCQSSEYVNQEYIK--GLLKRQTDGSMAYSE 346
TDL+LRC+L ++ +LIA+CC H C YV +++++ G+ R+
Sbjct: 283 TDLTLRCILGDGNASSDY--VLIALCCHHRCSWRSYVGRKFLQEAGIGPRE--------- 331
Query: 347 FFQCLKKFCSYCTCGLRPDMDPNSG--------SEDHITKLTHNERQRIGHMARRIIDEG 398
F L K S+ CG + +E + +LT ER++IG +R++D G
Sbjct: 332 -FVILTKMVSWAVCGTGLSRERRKAMESADFQLTETNTQRLTRQEREQIGQQCKRVLDYG 390
Query: 399 RAQFLQSKGFETVLFKYTDSAVTLEDTALLA 429
R + L+S G++ L Y VTLE+ LLA
Sbjct: 391 RLEHLRSHGYQAELKFYVPRDVTLENVVLLA 421
>Hs11024704 [S] KOG2811 Uncharacterized conserved protein
Length = 481
Score = 159 bits (402), Expect = 8e-39
Identities = 137/505 (27%), Positives = 212/505 (41%), Gaps = 139/505 (27%)
Query: 19 QCEFFLVKKKRQCGMTRRAGSQFCSEHSTDSD------RVPCPLDPSHTVCLSKMRVHMR 72
+C +++ KKKR C M AG +FC EH+ + R+ CPLDP HTV ++ H++
Sbjct: 18 RCGYYVEKKKRFCRMVVAAGKRFCGEHAGAMEEEDARKRILCPLDPKHTVYEDQLAKHLK 77
Query: 73 KCNKFRHDVSYQAKQREIPWFKEGLNSISNGKSDSKPADETLVKSVSLIQKIFQNEFGDE 132
KCN RE P + I+ G D E LV SL ++ E
Sbjct: 78 KCNS-----------REKPKPDFYIQDINAGLRDETEIPEQLVPISSLSEEQL------E 120
Query: 133 PPLPLIEKQNELLERTERYKTLVN----------------RKHARQQSSLIQHLKESKLW 176
+ + K +E L T + + + KH +QQ+S++ +++ KL
Sbjct: 121 KLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSATKHLKQQASILGNIENLKL- 179
Query: 177 PSLESCAVNKTLEYIELGCGRAEFSRYVNIATNLDQKEHSHEKPEYKAVAPSFTLIDRAS 236
+ ++E G G+ + S +V+IA +K H F L+++ +
Sbjct: 180 -------LGPRRCFVEFGAGKGKLSHWVDIALKDAEKVH-------------FILVEKVT 219
Query: 237 QRLRFDNKFSSDIGTEVQIRREKIDIKDLRLDAV---LHDASQYVAISKHLCGVATDLSL 293
R + D K R +IDI+ L L+ + + V I KHLCG+ATDL+L
Sbjct: 220 TRFKVDGKHRKKNSV---FERLQIDIQHLCLNKIPVLREEKLPVVGIGKHLCGMATDLAL 276
Query: 294 RCL-------------------LNSDKCKANL-------------------RGILIAMCC 315
RCL + +DK + + GI+IA+CC
Sbjct: 277 RCLVETYAASFEERNEEPLAKRIKNDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCC 336
Query: 316 RHVCQSSEYVNQEYIKGLLKRQTDGSMAYSEFFQCLKKFCSYCTCGLRPDM--------- 366
H C YV +EY + L + F ++ S+ TCG+R
Sbjct: 337 HHRCDWRHYVGKEYFRALGLGAVE--------FHYFQRMSSWATCGMRKTSLETSNSTTK 388
Query: 367 ---DPNSGSEDH------ITK---------LTHNERQRIGHMARRIIDEGRAQFLQSKGF 408
+ N SE+H IT L+ E+++IGH+ + +ID+GR Q+LQ KGF
Sbjct: 389 RQDNQNDDSEEHDDGGYRITDDGADCLPGLLSVEEKKKIGHLCKLLIDQGRIQYLQQKGF 448
Query: 409 ETVLFKYTDSAVTLEDTALLALRKH 433
L YTD V+LE+ L AL H
Sbjct: 449 SPALQYYTDPLVSLENVLLTALPNH 473
>SPAC1805.03c [S] KOG2811 Uncharacterized conserved protein
Length = 407
Score = 150 bits (380), Expect = 3e-36
Identities = 118/398 (29%), Positives = 188/398 (46%), Gaps = 62/398 (15%)
Query: 51 RVPCPLDPSHTVCLSKMRVHMRKCNKFRHDVSYQAKQREIPWFKEGLN-SISNGKSDSKP 109
++PCP D HT+ ++ H+++CN + +R P++K+ +N S S S+S
Sbjct: 54 QIPCPYDHKHTIVRHRLEYHLKRCNA-------RPVERTDPYYKKDINISTSTDASESSS 106
Query: 110 ADETLVKSVSLIQKI-FQNEFGDEPPLPLIEKQNELL---ERTERYKTLVNRKHARQQSS 165
+ + L + I N D P P Q ++L R + +KHA QQ+S
Sbjct: 107 FEIVDLSKEELSKWICLFNRISDSLPTP----QKKVLFHPAMNARLEEGTKKKHAIQQAS 162
Query: 166 LIQHLKESKLWPSLESCAVNKTLEYIELGCGRAEFSRYVNIATNLDQKEHSHEKPEYKAV 225
L+ H+++ + + S Y E G GRAE SRYV + Q+E+
Sbjct: 163 LLGHMEKLHYFDNQGSI-------YYEFGAGRAELSRYVQ---HCSQQENV--------- 203
Query: 226 APSFTLIDRASQRLRFDNKFSSDI----GTEVQIRREKIDIKDLRLDAVLHD----ASQY 277
+ LIDR S R + D++ D E +I R KIDIKDL+LD +
Sbjct: 204 ---YILIDRDSNRTKHDSRILKDSIKNNWPEPKIIRCKIDIKDLKLDFFASEFRNSGKPV 260
Query: 278 VAISKHLCGVATDLSLRCLLNSDKCKANLRGILIAMCCRHVCQ---SSEYVNQEYIKGLL 334
A SKHLCG ATDL+L CL +S ++IA+CC H C+ S + ++
Sbjct: 261 FAYSKHLCGAATDLTLNCLKSSPP-----NALVIALCCHHHCRWRTLSTFAREQL----- 310
Query: 335 KRQTDGSMAYSEFFQCLKKFCSYCTCGLRPDMDPNSGSEDHITKLTHNERQRIGHMARRI 394
+ ++ + FQ L++ + LR M + G++ HI+ L+H ER +IG + I
Sbjct: 311 ---SHWGISNPQEFQILRQMTGWAVNSLREHMHASGGADSHISGLSHEERVKIGLKCKHI 367
Query: 395 IDEGRAQFLQSKGFETVLFKYTDSAVTLEDTALLALRK 432
I+ R + G+E+ L Y TLE+ AL+A ++
Sbjct: 368 INYMRKLECEKMGYESSLVYYVGEETTLENVALIAYKR 405
>CE22211 [S] KOG2811 Uncharacterized conserved protein
Length = 390
Score = 138 bits (348), Expect = 1e-32
Identities = 114/434 (26%), Positives = 202/434 (46%), Gaps = 65/434 (14%)
Query: 12 QSTAERLQCEFFLVKKKRQCGMTRRAGSQFCSEHS----TDSDRVPCPLDPSHTVCLSKM 67
Q + CE+ L KKR+C M + G++FC EHS ++DR+ CP D HT+ + +
Sbjct: 8 QQQQQNACCEYILPIKKRRCKMLVKKGNRFCGEHSIHDQNNTDRMVCPNDGKHTILKADL 67
Query: 68 RVHMRKCNKFRHDVSYQAKQREIPWFKEGLNSI-----SNGKSDSKPADETLVKSVSLIQ 122
+H+ +CN ++ R+ + K NSI K D + ++ + +V I
Sbjct: 68 EIHLTRCN---------SRIRDAEYIKIDANSIRGETKRTDKIDRRATEDEICTTVHKIW 118
Query: 123 KIFQNEFGDEPPLPLIEKQNELLERTERYKTLVN---RKHARQQSSLIQHLKESKLWPSL 179
K ++ + D L + +++NEL+E+ + +N +K Q SS++ H++ + L P+
Sbjct: 119 KCYETDVMDR--LIVEQQRNELVEQNIAQNSDLNNTKKKQLYQISSILGHIESTGLLPTC 176
Query: 180 -ESCAVNKTLEYIELGCGRAEFSRYVNIATNLDQKEHSHEKPEYKAVAPSFTLIDRASQR 238
+SC ELG G+ + + +++ A A ++ L+DR+ R
Sbjct: 177 SKSC-------MFELGAGKGQLAYWISKA----------------APNGNYILMDRSGSR 213
Query: 239 LRFDN-KFSSDIGTEVQIRREKIDIKDLRLDAVLHDASQYVAISKHLCGVATDLSLRCLL 297
+FD F + ++ R I+ DL L ++ + +AI KH CG ATD +R L+
Sbjct: 214 NKFDTAAFRENPNLSMKRFRCSIEHMDLSKIDELKNSEKILAICKHFCGSATDAGIRSLM 273
Query: 298 NSDKCKANLRGILIAMCCRHVCQSSEYVNQEYIKGLLKRQTDGSMAYSEFFQCLKKFCSY 357
NS L+ CC H + +EY ++++ M F L+ S+
Sbjct: 274 NSG---LQFNAALLIPCCHHKSRFAEYGGHDFLE-------KWEMNDEASFAALRYIASF 323
Query: 358 CTCGLRPDMDPNSGSEDHITKLTHNERQRIGHMARRIIDEGRAQFLQSKGFETVLFKYTD 417
T G D + G + L +G A+ I++ GRA +L+S GF+T + +Y
Sbjct: 324 ATNG-AVDTEATEGWKSIHPPL------ELGRRAKAILEIGRAIWLESVGFKTRVVEYVP 376
Query: 418 SAVTLEDTALLALR 431
V+ E+ +LAL+
Sbjct: 377 PEVSPENLLILALK 390
>At4g01880 [S] KOG2811 Uncharacterized conserved protein
Length = 419
Score = 100 bits (248), Expect = 6e-21
Identities = 90/313 (28%), Positives = 140/313 (43%), Gaps = 71/313 (22%)
Query: 158 KHARQQSSLIQHLKESKLWPSLESCAVN-----KTLE---------YIELGCGRAEFSRY 203
KH QQ S++ +L+E + L+ C +N LE +E G GR ++
Sbjct: 129 KHVLQQGSILGNLEEIGV---LKRCNINVECCESDLEEKDDNTAPAVVEFGAGRGYLTQM 185
Query: 204 VNIATNLDQKEHSHEKPEYKAVAPSFTLIDRASQRLRFDNKFSSDIGTEVQIRREKIDIK 263
+ + K Y L++R S +L+ D + + R +IDI+
Sbjct: 186 LADCYGI--------KKVY--------LVERKSYKLKADRSLRQK--ESLVLERMRIDIE 227
Query: 264 DLRLDAV--LHDASQYVAISKHLCGVATDLSLRCLLN-SDKCKANLRGILIAMCCRHVCQ 320
DL L+AV LH YVA+ KHLCG ATDLSLRC L+ D LRG+ IA CC H+ Q
Sbjct: 228 DLNLNAVESLHGVP-YVAVGKHLCGPATDLSLRCCLSRQDGESPVLRGLAIATCCHHLSQ 286
Query: 321 SSEYVNQEYIKGLLKRQTDGSMAYSEFFQCLKKFCSYCTCGLRPD----------MDPNS 370
Y+N+EYI L + + F + F S+ +D N+
Sbjct: 287 WKSYINKEYILSLGISKDE--------FHIMTSFTSWAVDDDHGSKLPGVDDIDLLDSNA 338
Query: 371 GSEDH--------------ITKLTHNERQRIGHMARRIIDEGRAQFLQSKGFETVLFKYT 416
E+ + K+ ER +G ++IID GR ++++ G + L KY
Sbjct: 339 KEEEEGEVRDASLISVEEVVKKMKPMERAVLGFKCKQIIDAGRMKWVKKHGLNSKLVKYI 398
Query: 417 DSAVTLEDTALLA 429
++++ E+T L+A
Sbjct: 399 PASISPENTLLIA 411
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,096,487
Number of Sequences: 60738
Number of extensions: 1123328
Number of successful extensions: 3001
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2964
Number of HSP's gapped (non-prelim): 8
length of query: 434
length of database: 30,389,216
effective HSP length: 109
effective length of query: 325
effective length of database: 23,768,774
effective search space: 7724851550
effective search space used: 7724851550
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)