ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV1980 good Q KOG0029 Secondary metabolites biosynthesis, transport and catabolism Amine oxidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV1980 697983 696385 -533
(533 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR020w [Q] KOG0029 Amine oxidase 412 e-115
At3g59050 [Q] KOG0029 Amine oxidase 96 2e-19
At2g43020 [Q] KOG0029 Amine oxidase 87 8e-17
At1g65840 [Q] KOG0029 Amine oxidase 78 3e-14
7293950 [H] KOG0685 Flavin-containing amine oxidase 60 6e-09
7299064 [H] KOG0685 Flavin-containing amine oxidase 58 4e-08
At5g13700 [Q] KOG0029 Amine oxidase 57 5e-08
7303656 [H] KOG0685 Flavin-containing amine oxidase 57 9e-08
7295017 [H] KOG0685 Flavin-containing amine oxidase 55 3e-07
Hs4557735 [Q] KOG0029 Amine oxidase 52 3e-06
7293951 [H] KOG0685 Flavin-containing amine oxidase 52 3e-06
Hs4505093 [Q] KOG0029 Amine oxidase 51 4e-06
>YMR020w [Q] KOG0029 Amine oxidase
Length = 508
Score = 412 bits (1058), Expect = e-115
Identities = 229/504 (45%), Positives = 321/504 (63%), Gaps = 21/504 (4%)
Query: 38 VIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNG-KYDIGGSWHHDTL 96
VI+IGAGI+GLKA S L ++GI+ + +E+RDRVGGRL T G G KYDIG SWHHDTL
Sbjct: 11 VIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHHDTL 70
Query: 97 SNGLFMEEMSLPESE-RAGFVFDDEDRACLVDKKLGVLEVDQ---LECLAYEFEKWVEMR 152
+N LF+EE L ++ R FVFDD D +D++ G ++ D+ LE + E K+ E+
Sbjct: 71 TNPLFLEEAQLSLNDGRTRFVFDD-DNFIYIDEERGRVDHDKELLLEIVDNEMSKFAELE 129
Query: 153 YYDSLDVEDVSYFQLCIEFCFSRKEFLTDEQLYHLPQLLRYMELWHGVDWYALSGKWSGI 212
++ L V D S+FQL +++ R++FLT++Q+ +LPQL RY+ELWHG+DW LS K +
Sbjct: 130 FHQHLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELWHGLDWKLLSAKDTYF 189
Query: 213 EHNGRNALVLHYDKILARISNPV-KDKIHLSESVNLIKKLSNGKYQVNTDKGK-YLCDYC 270
H GRNA L+YD ++ RI+ ++ + LS V I + + VN + G Y DY
Sbjct: 190 GHQGRNAFALNYDSVVQRIAQSFPQNWLKLSCEVKSITREPSKNVTVNCEDGTVYNADYV 249
Query: 271 IVTVPQSVLAISCEQEENEFSHMRKARIGFEPPLNGDIFEAITTKASFGSLGKVIFEFDS 330
I+TVPQSVL +S + E+N + RI F+PPL I +A K FG+LGKVIFEF+
Sbjct: 250 IITVPQSVLNLSVQPEKN-----LRGRIEFQPPLKPVIQDAF-DKIHFGALGKVIFEFEE 303
Query: 331 IKWSKTSGRILTVHEQPTDFVESIRSAKDLKTLLKDIEQKLPRSHED--SWKNPTCFLNL 388
WS S +I+T+ +FVE +R+A++L L +E++ + H W P F+NL
Sbjct: 304 CCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSMLEREDSQKHTSVTCWSQPLFFVNL 363
Query: 389 AKHTDTASFVALIQQPVX--XXXXXXXXXXXXXFFRPVLNKLLNSLGSSDYISDLN--DE 444
+K T ASF+ L+Q P+ FF+PVLNK++ L S D I + +
Sbjct: 364 SKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMKCLDSEDVIDGMRPIEN 423
Query: 445 VKESKTPILKNILTSNWSSDPFSLGAYSACQPGDDPMDLVIALNVGQ-GNLRFAGEHTIM 503
+ + P+L+NI+ SNW+ DP+S GAYSAC PGDDP+D+V+A++ GQ +RFAGEHTIM
Sbjct: 424 IANANKPVLRNIIVSNWTRDPYSRGAYSACFPGDDPVDMVVAMSNGQDSRIRFAGEHTIM 483
Query: 504 DGAGCAYGAWESGKREANYIIEKL 527
DGAGCAYGAWESG+REA I + L
Sbjct: 484 DGAGCAYGAWESGRREATRISDLL 507
>At3g59050 [Q] KOG0029 Amine oxidase
Length = 488
Score = 95.5 bits (236), Expect = 2e-19
Identities = 133/495 (26%), Positives = 196/495 (38%), Gaps = 88/495 (17%)
Query: 37 SVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKYDIGGSWHHDTL 96
SVIVIG G++G+ A L + + V+ +ESRDR+GGR++T D+G SW H
Sbjct: 30 SVIVIGGGMAGISAARTLQDASFQ-VVVLESRDRIGGRVHTDYSFGFPVDLGASWLHGVC 88
Query: 97 SN---GLFMEEMSLPESERAG---FVFD-DEDRACLVDKKLGVLEVDQLECLAYEFEKWV 149
+ + LP +G ++D D + L DK + + + + FE +
Sbjct: 89 KENPLAAVIGRLGLPLYRTSGDNSVLYDHDLESYALFDKAGNQVSQELVTKVGENFEHIL 148
Query: 150 E--MRYYDSLDVEDVSYFQLCIEFCFSRKEFLTDEQLYH--LPQLLRYMELWHGVDWYAL 205
E + D D ED+S Q F R L E L H L L ME W D +
Sbjct: 149 EEICKVRDEQD-EDMSIAQ-AFSIVFKRNPELRLEGLAHNVLQWYLCRMEGWFAADAETI 206
Query: 206 SGK-WSGIE--HNGRNALVLHYDKILARISNPVKDKIHLSESVNLIKKLSNGKYQVNTDK 262
S K W E G +V Y ++ +S + I LS + I + +G +V T+K
Sbjct: 207 SAKCWDQEELLPGGHGLMVRGYRPVINTLSKGL--DIRLSHRITKISRRYSG-VKVTTEK 263
Query: 263 G-KYLCDYCIVTVPQSVLAISCEQEENEFSHMRKARIGFEPPLNGDIFEAITTKASFGSL 321
G ++ D ++ +P VL + I FEP L EAI G
Sbjct: 264 GDTFVADAAVIALPLGVL--------------KSGMITFEPKLPQWKQEAI-NDLGVGIE 308
Query: 322 GKVIFEFDSIKWSKTSGRILTVHEQPTDFVESIRSAKDLKTLLKDIEQKLPRSHEDSWKN 381
K+I FD++ W +F+ + S+ S+
Sbjct: 309 NKIILNFDNVFWPN------------VEFLGVVAET----------------SYGCSY-- 338
Query: 382 PTCFLNLAKHTDTASFVALIQQPVXXXXXXXXXXXXXXFFRPVLNKLLNSLGSSDYISDL 441
FLNL K T S L+ P + K + ++ S L
Sbjct: 339 ---FLNLHKAT---SHPVLVYMPAGQLARD-------------IEKKSDEAAANFAFSQL 379
Query: 442 NDEVKESKTPILKNILTSNWSSDPFSLGAYSACQPGDDPMDLVIALNVGQGNLRFAGEHT 501
+ ++ +PI N L S W SD SLG+YS + P DL L V NL FAGE T
Sbjct: 380 QKILPDASSPI--NYLVSRWGSDINSLGSYS-YDIVNKPHDLYERLRVPLDNLFFAGEAT 436
Query: 502 IMDGAGCAYGAWESG 516
G +GA+ +G
Sbjct: 437 SSSYPGSVHGAYSTG 451
>At2g43020 [Q] KOG0029 Amine oxidase
Length = 490
Score = 86.7 bits (213), Expect = 8e-17
Identities = 131/511 (25%), Positives = 199/511 (38%), Gaps = 90/511 (17%)
Query: 23 RSHCASL--RIIMTDYSVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQG 80
R++C S R+ SVIVIG G G+ A L + + V+ +ESRDR+GGR++T
Sbjct: 13 RANCFSAGERMKTRSPSVIVIGGGFGGISAARTLQDASFQ-VMVLESRDRIGGRVHTDYS 71
Query: 81 RNGKYDIGGSWHHDTLSNGLF---MEEMSLPESERAG---FVFD-DEDRACLVDKKLGVL 133
D+G SW H + + LP +G ++D D + L D +
Sbjct: 72 FGFPVDLGASWLHGVCKENPLAPVIGRLGLPLYRTSGDNSVLYDHDLESYALFDMDGNQV 131
Query: 134 EVDQLECLAYEFEKWVE--MRYYDSLDVEDVSYFQLCIEFCFSRKEFLTDEQLYH--LPQ 189
+ + + FE+ +E + D D D+S Q FSRK L E L H L
Sbjct: 132 PQELVTQIGVTFERILEEINKVRDEQDA-DISISQ-AFSIVFSRKPELRLEGLAHNVLQW 189
Query: 190 LLRYMELWHGVDWYALSGK-WSGIE--HNGRNALVLHYDKILARISNPVKDKIHLSESVN 246
+ ME W D +S K W E G +V Y ++ ++ + I + V
Sbjct: 190 YVCRMEGWFAADAETISAKCWDQEELLPGGHGLMVRGYRPVINTLAKGL--DIRVGHRVT 247
Query: 247 LIKKLSNGKYQVNTDKGK-YLCDYCIVTVPQSVLAISCEQEENEFSHMRKARIGFEPPLN 305
I + NG +V T+ G+ ++ D ++ VP VL + I FEP L
Sbjct: 248 KIVRRYNG-VKVTTENGQTFVADAAVIAVPLGVL--------------KSGTIKFEPKLP 292
Query: 306 GDIFEAITTKASFGSLGKVIFEFDSIKWSKTSGRILTVHEQPTDFVESIRSAKDLKTLLK 365
EAI G K+I F+ + W K +F+ +
Sbjct: 293 EWKQEAI-NDLGVGIENKIILHFEKVFWPK------------VEFLGVVAET-------- 331
Query: 366 DIEQKLPRSHEDSWKNPTCFLNLAKHTDTASFVALIQQPVXXXXXXXXXXXXXXFFRPVL 425
S+ S+ FLNL K T L+ P +
Sbjct: 332 --------SYGCSY-----FLNLHKAT---GHPVLVYMPAGQLAKD-------------I 362
Query: 426 NKLLNSLGSSDYISDLNDEVKESKTPILKNILTSNWSSDPFSLGAYSACQPGDDPMDLVI 485
K+ + ++ + L + ++ P+ L S W SD S+G+YS G P DL
Sbjct: 363 EKMSDEAAANFAVLQLQRILPDALPPV--QYLVSRWGSDVNSMGSYSYDIVG-KPHDLYE 419
Query: 486 ALNVGQGNLRFAGEHTIMDGAGCAYGAWESG 516
L V NL FAGE T G +GA+ +G
Sbjct: 420 RLRVPVDNLFFAGEATSSSFPGSVHGAYSTG 450
>At1g65840 [Q] KOG0029 Amine oxidase
Length = 497
Score = 78.2 bits (191), Expect = 3e-14
Identities = 127/514 (24%), Positives = 187/514 (35%), Gaps = 99/514 (19%)
Query: 37 SVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKYDIGGSWHHDTL 96
SVIVIG+GISGL A +L ++ + V +ESRDR+GGR++T D+G SW H
Sbjct: 30 SVIVIGSGISGLAAARNLSEASFK-VTVLESRDRIGGRIHTDYSFGCPVDMGASWLH--- 85
Query: 97 SNGLFMEEMSLPESERAGFVF--DDEDRACLVDKKL---GVLEV------DQLECLAYEF 145
G+ E P R G D + L D L G+ ++ QL +
Sbjct: 86 --GVSDENPLAPIIRRLGLTLYRTSGDDSILYDHDLESYGLFDMHGNKIPPQLVTKVGDA 143
Query: 146 EKWV--EMRYYDSLDVEDVSYFQLCIEFCFSRKEFLTDEQLYH--LPQLLRYMELWHGVD 201
K + E D+S Q I R L E + + L L ME W VD
Sbjct: 144 FKRILEETEKIRDETANDMSVLQ-GISIVLDRNPELRQEGMAYEVLQWYLCRMEAWFAVD 202
Query: 202 WYALSGK-WSGIE--HNGRNALVLHYDKILARISNPVKDKIHLSESVNLIKKLSNGKYQV 258
+S K W E G +V Y+ ++ I+ + I L+ V + + SN K V
Sbjct: 203 ANLISLKCWDQDECLSGGHGLMVQGYEPVIRTIAKDL--DIRLNHRVTKVVRTSNNKVIV 260
Query: 259 NTDKG-KYLCDYCIVTVPQSVLAISCEQEENEFSHMRKARIGFEPPLNGDIFEAITTKAS 317
+ G ++ D I+TVP VL + Q E E + + I +
Sbjct: 261 AVEGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKTSAI---------------SGLG 305
Query: 318 FGSLGKVIFEFDSIKWSKTSGRILTVHEQPTDFVESIRSAKDLKTLLKDIEQKLPRSHED 377
G+ K+ FD W +F+ + P S+
Sbjct: 306 VGNENKIALRFDRAFWPN------------VEFLGMV----------------APTSYAC 337
Query: 378 SWKNPTCFLNLAKHTDTASFVALIQQPVXXXXXXXXXXXXXXFFRPVLNKLLNSLGSSDY 437
+ FLNL K T V + + F L K+
Sbjct: 338 GY-----FLNLHKATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMF-------- 384
Query: 438 ISDLNDEVKESKTPILKNILTSNWSSDPFSLGAYSACQPGDDPMDLVIALNVGQGNLRFA 497
P L + W +DP +LG Y+ G P DL L N+ F
Sbjct: 385 ----------PDAPDPAQYLVTRWGTDPNTLGCYAYDVVG-MPEDLYPRLGEPVDNIFFG 433
Query: 498 GEHTIMDGAGCAYGAWESGKREA----NYIIEKL 527
GE ++ G A+GA+ +G + YI E+L
Sbjct: 434 GEAVNVEHQGSAHGAFLAGVSASQNCQRYIFERL 467
>7293950 [H] KOG0685 Flavin-containing amine oxidase
Length = 479
Score = 60.5 bits (145), Expect = 6e-09
Identities = 27/77 (35%), Positives = 45/77 (58%)
Query: 38 VIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKYDIGGSWHHDTLS 97
+++IGAG SG+ A + L++ G ++V+ E+ DR+GGR+NT N D+G W H
Sbjct: 19 IVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEEG 78
Query: 98 NGLFMEEMSLPESERAG 114
N ++ + L +R G
Sbjct: 79 NVVYEKVKDLDVLDRTG 95
>7299064 [H] KOG0685 Flavin-containing amine oxidase
Length = 583
Score = 57.8 bits (138), Expect = 4e-08
Identities = 25/69 (36%), Positives = 45/69 (64%), Gaps = 1/69 (1%)
Query: 34 TDYSVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRL-NTRQGRNGKYDIGGSWH 92
T+ +++IGAG++GL A + L+++G + + +E+R RVGGR+ + N K ++G +W
Sbjct: 38 TNVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELGANWI 97
Query: 93 HDTLSNGLF 101
H L N +F
Sbjct: 98 HGVLGNPIF 106
>At5g13700 [Q] KOG0029 Amine oxidase
Length = 472
Score = 57.4 bits (137), Expect = 5e-08
Identities = 25/59 (42%), Positives = 41/59 (69%)
Query: 33 MTDYSVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKYDIGGSW 91
M+ SVI+IGAGISG+ A LV++G+E V+ +E+ DR+GGR++ + + ++G W
Sbjct: 1 MSTASVIIIGAGISGISAAKVLVENGVEDVLILEATDRIGGRIHKQNFGDVPVELGAGW 59
>7303656 [H] KOG0685 Flavin-containing amine oxidase
Length = 509
Score = 56.6 bits (135), Expect = 9e-08
Identities = 75/325 (23%), Positives = 136/325 (41%), Gaps = 45/325 (13%)
Query: 35 DYSVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKYDIGGSWHHD 94
D ++VIGAG SG+ + L++ G ++V+ +E+ DR+GGR++T + D+G W H
Sbjct: 9 DRKIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHG 68
Query: 95 TLSNGLFMEEMSLPES--ERAGFVFDDEDRACL----------VDKKLGVLEVDQLECLA 142
N ++ E E G V+ E+ C+ V +L + D L
Sbjct: 69 ERDNIVYELTRKQDEELLESTGPVY--ENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQ 126
Query: 143 YEFE-------KWVEMRYYDSLDVEDVSYF--QLCIEFCFSRKEFLTDEQLYHLPQLLR- 192
E ++ ++YD+L + S ++ EF + ++F + + +
Sbjct: 127 LELRHCSGSLGSYLTNKFYDTLRRPENSDIDAEVASEFFVNYQKFENSVEASDTLEQVSG 186
Query: 193 --YMELWHGVDWYALSGKWSGIEHNGRNALVLHYDKILARISNPVKDKIHLSESVNLIK- 249
Y++ W L+ K G R +L + L ++ ++ L V I
Sbjct: 187 RGYLDYWECEGDILLNWKDKGYVELLR---LLMRSRELNVEHGVLEQRLLLGTRVVKINW 243
Query: 250 KLSNGKYQVNTDKGK-YLCDYCIVTVPQSVLAISCEQEENEFSHMRKARIGFEPPLNGDI 308
++G+ ++ G+ + D+ +VTV VL + H+R FEP L +
Sbjct: 244 NRNDGRVELQMSNGETCIADHVVVTVSLGVL---------KDQHLRL----FEPQLPVEK 290
Query: 309 FEAITTKASFGSLGKVIFEFDSIKW 333
AI A FG++ K+ EF W
Sbjct: 291 QRAIDGLA-FGTVNKIFVEFPEAFW 314
>7295017 [H] KOG0685 Flavin-containing amine oxidase
Length = 476
Score = 55.1 bits (131), Expect = 3e-07
Identities = 23/64 (35%), Positives = 41/64 (63%)
Query: 38 VIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKYDIGGSWHHDTLS 97
+I+IGAG+SG+ A + L+++ ++V +E+ DR+GGR+NT + D+G W H
Sbjct: 10 IIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDNVIDLGAQWCHGKQQ 69
Query: 98 NGLF 101
N ++
Sbjct: 70 NCVY 73
>Hs4557735 [Q] KOG0029 Amine oxidase
Length = 527
Score = 51.6 bits (122), Expect = 3e-06
Identities = 35/84 (41%), Positives = 49/84 (57%), Gaps = 8/84 (9%)
Query: 36 YSVIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKY-DIGGSWHHD 94
+ V+VIG GISGL A L + G+ SV+ +E+RDRVGGR T + + Y D+GG++
Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGV-SVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGP 72
Query: 95 T------LSNGLFMEEMSLPESER 112
T LS L +E + SER
Sbjct: 73 TQNRILRLSKELGIETYKVNVSER 96
>7293951 [H] KOG0685 Flavin-containing amine oxidase
Length = 468
Score = 51.6 bits (122), Expect = 3e-06
Identities = 24/78 (30%), Positives = 45/78 (56%), Gaps = 3/78 (3%)
Query: 27 ASLRIIMTDYS---VIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNG 83
ASLR++ ++++GAG +G+ A + L+ G +V+ +E+ DR+GGR++T +
Sbjct: 4 ASLRLLSKTRQTARIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADN 63
Query: 84 KYDIGGSWHHDTLSNGLF 101
D+G W H N ++
Sbjct: 64 VVDLGAQWCHGEKGNVVY 81
>Hs4505093 [Q] KOG0029 Amine oxidase
Length = 520
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/82 (41%), Positives = 49/82 (59%), Gaps = 8/82 (9%)
Query: 38 VIVIGAGISGLKATSDLVKSGIESVICIESRDRVGGRLNTRQGRNGKY-DIGGSWHHDT- 95
V+V+G GISG+ A L SG+ +V+ +E+RDRVGGR T + + KY D+GGS+ T
Sbjct: 7 VVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65
Query: 96 -----LSNGLFMEEMSLPESER 112
L+ L +E + E ER
Sbjct: 66 NRILRLAKELGLETYKVNEVER 87
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,549,019
Number of Sequences: 60738
Number of extensions: 1482950
Number of successful extensions: 3670
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3635
Number of HSP's gapped (non-prelim): 23
length of query: 533
length of database: 30,389,216
effective HSP length: 111
effective length of query: 422
effective length of database: 23,647,298
effective search space: 9979159756
effective search space used: 9979159756
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)