ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2029 good EO KOG1046 Amino acid transport and metabolism Puromycin-sensitive aminopeptidase and related aminopeptidases
r_klactV2029 good EO KOG1046 Posttranslational modification, protein turnover, chaperones Puromycin-sensitive aminopeptidase and related aminopeptidases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2029 712370 715054 895
(895 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL137c [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 757 0.0
YKL157w [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 238 3e-62
YHR047c [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 223 1e-57
7299747 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 195 3e-49
Hs15451907 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 194 5e-49
SPBC1921.05 [EO] KOG1046 Puromycin-sensitive aminopeptidase and ... 189 2e-47
Hs5031881 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 188 4e-47
7292091 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 184 4e-46
Hs20534524 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 180 1e-44
Hs4503575 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 179 2e-44
CE21162 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 175 2e-43
7301517 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 172 2e-42
CE18905 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 172 2e-42
CE10790 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 170 1e-41
7299744 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 167 5e-41
Hs20149637 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 165 3e-40
CE24087 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 160 6e-39
Hs7019561 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 160 8e-39
7301772 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 157 9e-38
Hs4502095 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 154 8e-37
Hs11641261 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 152 2e-36
ECU08g0070 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 152 3e-36
7299745 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 150 8e-36
ECU01g1470 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 150 1e-35
ECU01g0140 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 150 1e-35
7300769 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 146 2e-34
7301771 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 144 5e-34
7300768 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 144 6e-34
7300767 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 144 8e-34
CE18904 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 143 1e-33
CE20255 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 142 2e-33
Hs22064092 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 141 4e-33
7301770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 141 5e-33
7301751 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 137 1e-31
CE26001 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 130 7e-30
CE27507 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 128 4e-29
7291179 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 124 6e-28
7291558 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 120 9e-27
CE05135 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 103 1e-21
At4g33090 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 102 3e-21
CE13593 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 100 8e-21
7298258 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 98 6e-20
CE24840 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 77 9e-14
7291178 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 76 3e-13
Hs4505029 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/a... 74 1e-12
CE28160 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 72 3e-12
7294697 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 72 4e-12
CE19614 [K] KOG1932 TATA binding protein associated factor 70 1e-11
At5g13520 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/a... 68 6e-11
YNL045w [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 65 4e-10
SPCC1322.05c [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolas... 64 8e-10
Hs20537652 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 63 2e-09
Hs13443031 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 61 7e-09
At1g63770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 56 3e-07
Hs17472410 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 55 5e-07
7300975 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 53 2e-06
>YIL137c [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 946
Score = 757 bits (1954), Expect = 0.0
Identities = 414/939 (44%), Positives = 596/939 (63%), Gaps = 49/939 (5%)
Query: 2 ILSLTEPVVPLEYTLDLNVDHKQ--PNFKGQLTVQLKQRQPG-------QSFNKFKFHCK 52
+LSL PVVP Y L L +D KQ PNFKG + LK SF +FK H K
Sbjct: 5 LLSLENPVVPSHYELRLEIDPKQSSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSK 64
Query: 53 QLIVTKV---LLSDK-PLSISYDANEQTVSFSSDDPLNIADDTAE-LRISYIGKVNTIKT 107
LIV + S K L IS D + F+S+ P+ +++D L + Y+GK+ IKT
Sbjct: 65 DLIVLSAHATIGSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKT 124
Query: 108 HRELTTGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDK 167
H + T G+FKTNFM TG ++++++ATH QP A +IFPC DEP++K +QL + D +
Sbjct: 125 HHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQ 184
Query: 168 FKVISNTSVENRSVTDD-RKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLK-NKTIPV 225
+K +SNT VE D +K +VKF+KTPLM TS FGF IGDLEFL+T++KL+ ++TIPV
Sbjct: 185 YKAVSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIPV 244
Query: 226 QLFAPQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQ 285
++AP I++A ++ DT+ + LP++E YPL KLD VLLP+LSDMAMEN+G++T Q
Sbjct: 245 SIYAPWDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQ 304
Query: 286 MNHLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLL 345
+NHLL+ P AL++ +V +Q +QLIVHEL HQWMGNYISFDSW+ LWFNE+FATW AC +L
Sbjct: 305 LNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHIL 364
Query: 346 DEH-DNDGYWSSDVY-LTQMENVISTD-AEVTTKSITQGSVIDVKSLQSTSDAFEPHIYH 402
+++ D YW+S+ Y L Q+E + D A+V +SI Q + + TSD F+P Y
Sbjct: 365 EQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYT 424
Query: 403 KGISLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYS 462
KGI +LRSLQ + G+ + + L +F ++ TFH +KPMDI+ +G+ LKS+NI NF S
Sbjct: 425 KGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLKSQNITNFVS 484
Query: 463 SWTRTPGIPIISVNTDTE----RTTLEQHRFL-----LEKTDVEDIPYHIPLFAVQSSGE 513
SWTRTPG+P++ V + + +T L QHRF+ EK +ED+PY +PLF V G+
Sbjct: 485 SWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGK 544
Query: 514 DDTKNGLFTDRTLKLSEPELIVNSGARGLYRVSYETDKCYELINEALKNSKISDLDLFKI 573
DTKN L TDRTLK P L++N A+G YRVSYE+++CY LIN+ + +S++DL KI
Sbjct: 545 MDTKNVLLTDRTLKFDYPILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRKI 604
Query: 574 FIDLRSLIGSE-YQKKIHIDGVLMILRCLAS-HVDLTEELYRGLSIGLDILQTIENALRT 631
F+DL IG E +Q IH+ G+ IL +AS + + + LS GL++LQTI+ A T
Sbjct: 605 FLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLT 664
Query: 632 YTGKSEKAFITDIYVPLWDKFSWN----DFHVSSYQLKVMSKVMFGIKHLDSTLTVANQL 687
+ K + I +PL++K W D + ++LKVMS+V+F K+ +
Sbjct: 665 -SSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAELCQIY 723
Query: 688 MKKILSGPNKSIPLELCGSVFATVSCHQKNVKQWKKLYELVK--SAKGVESHV----DGG 741
K +L GP S+PLEL S+ VS H N+KQWKK+++LVK S G+ +HV D
Sbjct: 724 FKHLLQGPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQN 783
Query: 742 SS---IDIQNMALENLAFNTNEELIKKTLNFILTNITSTSVENALFGLNYNFREPL---D 795
SS + IQN A+E+L F + +++KKTLNFI +NI S +E ALFG NYNF++ L +
Sbjct: 784 SSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNE 843
Query: 796 GKKNKLVRDVCWEWFELNYDLWGRKSLREGAESSERMKKTLVHISYVIFQMWM-DNPEKV 854
++++VR+ WEW+ N+D W RK+ R+G + + + K L IS +IFQM++ D P+K+
Sbjct: 844 KPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMFVADEPQKI 903
Query: 855 DEFVTKKNATYGQT-LGTAQIWTAVKASESSKMNIYKGI 892
++F+ + GQ+ L IW +V+ E S+ I + +
Sbjct: 904 EKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDL 942
>YKL157w [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 935
Score = 238 bits (607), Expect = 3e-62
Identities = 217/826 (26%), Positives = 375/826 (45%), Gaps = 70/826 (8%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDK 64
L + VVPL Y L + D K F+G + ++LK P + + + + + D
Sbjct: 102 LPDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNP--AIDTVTLNTVDTDIHSAKIGDV 159
Query: 65 PLS--ISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMS 122
S IS + + T ++ A L I + G +N + G ++ +
Sbjct: 160 TSSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILN------DNMAGFYRAKYED 213
Query: 123 DTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVT 182
TG Y+ T +P AR FPCFDEPN K + +TL +D +SN V+N V
Sbjct: 214 KLTG-ETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVK 272
Query: 183 DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHATYSFD 241
D +K + F+ TP M+T F + +L++ V+ KN IPV+++A P + H ++ D
Sbjct: 273 DGKK-VTLFNTTPKMSTYLVAFIVAELKY----VESKNFRIPVRVYATPGNEKHGQFAAD 327
Query: 242 TIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSV 301
+ L EK G+ YPL K+D V + S AMENWGL+T+++ LLL S
Sbjct: 328 LTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDN-STLDR 386
Query: 302 IQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLT 361
IQ+V +++ HEL HQW GN ++ D W+ LW NE FATW + +E +
Sbjct: 387 IQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTD 446
Query: 362 QMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFN 421
+++ +S D+ ++ I + VK + F+ Y KG SLLR + + +G+E F
Sbjct: 447 TLQHALSLDSLRSSHPIE----VPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFI 502
Query: 422 RALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTD-TE 480
+ ++Q ++ F K D++ + + +++ + + WT+ G P+ISV+ D
Sbjct: 503 KGVSQYLNK---FKYGNAKTEDLWDALAD-ASGKDVRSVMNIWTKKVGFPVISVSEDGNG 558
Query: 481 RTTLEQHRFLLE---KTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLSEPELI-VN 536
+ T Q+R+L K D + Y + L +G D + +T++L +P VN
Sbjct: 559 KITFRQNRYLSTADVKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELEDPTFFKVN 618
Query: 537 SGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFIDLRSLIGSEYQKKIHIDGVLM 596
S G+Y SY ++ +L +A +S D + D+++L S Y + ++
Sbjct: 619 SEQSGIYITSYTDERWAKLGQQA---DLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVS 675
Query: 597 ILRCLASHV---DLTEELYRGLSIGLDILQTIENALRTYTGKSEKAFITDIYVPLWDKFS 653
S V + + S L + ++AL +T K I+ + L +F
Sbjct: 676 KWNNEKSFVVWDQIINSISSMKSTWLFEPKETQDALDNFT----KQLISGMTHHLGWEFK 731
Query: 654 WNDFHVSSYQLKVMSKVMFGIKHLDSTLTVANQLMKKI---LSGPNKSIPLELCGSVFAT 710
+D S+ +LKV MFG V +K SG ++IP + VF T
Sbjct: 732 SSD-SFSTQRLKV---TMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNT 787
Query: 711 VSCHQKNVKQWKKLYELVKSAKGVESHVDGGSSIDIQNMALENLAFNTNEELIKKTLNFI 770
V+ + ++K+Y++ ++D S+ D + AL +L +L+++TL ++
Sbjct: 788 VA-RVGGAENYEKVYKI---------YLDPISN-DEKLAALRSLGRFKEPKLLERTLGYL 836
Query: 771 LTNITSTSVENALFGLNYNFREPLDG-KKNKLVRDVCWEWFELNYD 815
LN + P+ G + ++ + W W + N+D
Sbjct: 837 FDGTV----------LNQDIYIPMQGMRAHQEGVEALWNWVKKNWD 872
>YHR047c [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 856
Score = 223 bits (567), Expect = 1e-57
Identities = 196/827 (23%), Positives = 372/827 (44%), Gaps = 73/827 (8%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSD- 63
L V PL Y + L + + F+G L + L+ S N + + ++ +
Sbjct: 6 LPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQIND--HSINSVQINYLEIDFHSARIEGV 63
Query: 64 KPLSISYDANEQ--TVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFM 121
+ ++ + N+Q T+ F + N+ +A+L I + G +N + G ++ +
Sbjct: 64 NAIEVNKNENQQKATLVFPNGTFENLGP-SAKLEIIFSGILN------DQMAGFYRAKYT 116
Query: 122 SDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSV 181
TG Y+ T + AR FPCFDEPN K + +TL ++ +SN V N ++
Sbjct: 117 DKVTG-ETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETI 175
Query: 182 TDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHATYSF 240
+ +K F+ TP M+T F + DL ++ ++ N IPV++++ P ++
Sbjct: 176 KEGKKYTT-FNTTPKMSTYLVAFIVADLRYVESN----NFRIPVRVYSTPGDEKFGQFAA 230
Query: 241 DTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPS 300
+ L E ++YPL K+D+V + S AMENWGL+T+++ LLL + S
Sbjct: 231 NLAARTLRFFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIEN-SSLD 289
Query: 301 VIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYL 360
IQ+V ++I HEL HQW GN ++ D W+ LW NE FATW + ++ +
Sbjct: 290 RIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVT 349
Query: 361 TQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENF 420
++ ++ D+ ++ I + V + + F+ Y KG SLLR + + +G+E F
Sbjct: 350 DNLQRALNLDSLRSSHPIE----VPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETF 405
Query: 421 NRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTE 480
+ ++Q ++ F K D++ + + +++ + + WT+ G P++SV
Sbjct: 406 IKGVSQYLNK---FKYGNAKTGDLWDALAD-ASGKDVCSVMNIWTKRVGFPVLSVKEHKN 461
Query: 481 RTTLEQHRFLLE---KTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLSEPELI-VN 536
+ TL QHR+L K + + Y I L S+G D+T T +L E +N
Sbjct: 462 KITLTQHRYLSTGDVKEEEDTTIYPILLALKDSTGIDNTLVLNEKSATFELKNEEFFKIN 521
Query: 537 SGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFIDLRSLIGSEYQKKIHIDGVLM 596
G++ SY ++ +L +A + +S D + D ++L S Y + ++
Sbjct: 522 GDQSGIFITSYSDERWAKLSKQA---NLLSVEDRVGLVADAKALSASGYTSTTNFLNLIS 578
Query: 597 ILRCLASHVDLTEELYRGLSIGLDIL----QTIENALRTYTGKSEKAFITDIYVPLWDKF 652
+ S V + E++ LS + I NAL +T D+ + +
Sbjct: 579 NWKNEDSFV-VWEQIINSLSALKSTWVFEPEDILNALDKFT--------LDLVLNKLSEL 629
Query: 653 SWNDFHVSSYQLKVMSKVMFG---IKHLDSTLTVANQLMKKILSGPNKSIPLELCGSVFA 709
WN S+ ++ + +F + ++A ++ ++ +G ++IP VF
Sbjct: 630 GWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYANGNKQAIPALFKAVVFN 689
Query: 710 TVSCHQKNVKQWKKLYELVKSAKGVESHVDGGSSIDIQNMALENLAFNTNEELIKKTLNF 769
TV+ ++K++ + ++ E + +AL L ++EL+++TL++
Sbjct: 690 TVA-RLGGENNYEKIFNIYQNPVSSEEKI----------IALRALGRFEDKELLERTLSY 738
Query: 770 ILTNITSTSVENALFGLNYNFREPLDG-KKNKLVRDVCWEWFELNYD 815
+L LN +F P+ G + +K + W W + ++D
Sbjct: 739 LLDGTV----------LNQDFYIPMQGIRVHKKGIERLWAWMQEHWD 775
>7299747 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 985
Score = 195 bits (495), Expect = 3e-49
Identities = 181/727 (24%), Positives = 338/727 (45%), Gaps = 99/727 (13%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLL--- 61
L + + P +Y L L D ++ N+ G +++ L+ +P H KQL V+ V +
Sbjct: 144 LPKQIKPSKYRLHLRPDLERKNYSGNISISLQVLEP---IAFIPVHVKQLNVSTVEVKRL 200
Query: 62 --SDKPL-------SISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELT 112
S PL + ++ E V+ + PL + + L +++ G + +
Sbjct: 201 DESGAPLKDITPTLTFAHPEFEYWVT-EFEQPLEAGNYS--LLLNFTGSLV------DRI 251
Query: 113 TGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLT--ADDKFKV 170
TG+++++++ S S I++T +P +AR FPCFDEP K ++ +T+ + D++ V
Sbjct: 252 TGMYQSSYLDKLKNRSRS-IISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHV 310
Query: 171 ISNTSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAP 230
+SN V + V D ++ F++T M+T F + D ++ T V+ +I ++++AP
Sbjct: 311 LSNMPVASEYVDGDITEVT-FAETVPMSTYLAAFVVSDFQYKETTVE--GTSIALKVYAP 367
Query: 231 QS-ISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHL 289
+ + Y+ DT ++ V Y L KLD+V +P AMENWGL+TF+ L
Sbjct: 368 PAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETAL 427
Query: 290 LLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHD 349
L S + Q+V ++ HEL HQW GN ++ + W+ LW NE FA++ + +
Sbjct: 428 LYDESTSSSVNK-QRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVKQMH 486
Query: 350 NDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLR 409
+ + + ++ V++ DA + + I V ++S ++ F+ Y KG +L+R
Sbjct: 487 PEWDMDNQFVIEELHPVLTIDATLASHPI----VKSIESPAEITEYFDTITYSKGAALVR 542
Query: 410 SLQQSVGKENFNRA-----LAQIFSESSTFHETCIKPMDIFRRMGEILKSE-NIANFYSS 463
L+ VG+E A + I+S ++T D + E E ++ +
Sbjct: 543 MLENLVGEEKLRNATTRYLVRHIYSTATT--------EDYLTAVEEEEGLEFDVKQIMQT 594
Query: 464 WTRTPGIPIISVNTDTERTTLEQHRFLLEKTDVE--------DIPYHIPLFAVQSSGEDD 515
WT G+P++ V L Q RFL + D + + IP+ SS +
Sbjct: 595 WTEQMGLPVVEVEKSGSTYKLTQKRFLANEDDYAAEAEASSFNYRWSIPI-TYTSSINSE 653
Query: 516 TKNGLF--TDRTLKLSEPE----LIVNSGARGLYRVSYETDKCYELINEALKNSK--ISD 567
++ +F D ++ PE + +N+ G YRV+Y +++ ELI+ ALKNS+ S
Sbjct: 654 VQSLIFNHNDNEATITLPEEASWIKINTNQVGYYRVNYGSEQWAELIS-ALKNSRETFST 712
Query: 568 LDLFKIFIDLRSLIGS-EYQKKIHIDGVLMILRCLASHVDLTEELYRGLSIGLDILQTIE 626
D + D +L + + + +D L S+++ +E+ Y S+G L T+
Sbjct: 713 ADRAHLLNDANTLAAAGQLNYSVALD--------LISYLE-SEQDYVPWSVGTSALATLR 763
Query: 627 NALRTYTGKSEKAFITDIYVPLWDKFSWNDFHVSSYQLKVMSKVMFGIKHLDSTLTVANQ 686
N + + TD+Y + ++Y K+++ ++ + + + N+
Sbjct: 764 N----------RVYYTDLYT-----------NYTTYARKLLTPIVEKVTFTVAADHLENR 802
Query: 687 LMKKILS 693
L K+LS
Sbjct: 803 LRIKVLS 809
>Hs15451907 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 875
Score = 194 bits (493), Expect = 5e-49
Identities = 169/677 (24%), Positives = 305/677 (44%), Gaps = 63/677 (9%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQL-IVTKVLLSD 63
L V P+ Y+L L D F+G+L + RQ + N+ +C + I+T +
Sbjct: 10 LPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQ---ATNQIVMNCADIDIITASYAPE 66
Query: 64 KPLSI-----SYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKT 118
I +Y ++ V+ S P + T L+I ++G++N + G +++
Sbjct: 67 GDEEIHATGFNYQNEDEKVTLSF--PSTLQTGTGTLKIDFVGELN------DKMKGFYRS 118
Query: 119 NFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVEN 178
+ + + + Y T + AR FPC+DEP K + ++L +SN +V +
Sbjct: 119 KYTTPSGEVR--YAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVID 176
Query: 179 RSVTDDRKQIV--KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQS-ISH 235
R D + +V KF++TP+M+T F +G+ +F+ T K + V+++ P
Sbjct: 177 RKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSK---DGVCVRVYTPVGKAEQ 233
Query: 236 ATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQA 295
++ + + LP + V YPL K+D++ + + AMENWGL+T++ LL+ P+
Sbjct: 234 GKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKN 293
Query: 296 LSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLD----EHDND 351
S S Q V ++ HEL HQW GN ++ + W HLW NE FA+W +D E+D
Sbjct: 294 -SCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIW 352
Query: 352 GYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSL 411
+ S Y E ++ S+ S +D + F+ Y KG S++R L
Sbjct: 353 TQFVSADYTRAQELDALDNSHPIEVSVGHPSEVD--------EIFDAISYSKGASVIRML 404
Query: 412 QQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIP 471
+G ++F + + ++ F + D++ + E + IA ++WT+ G P
Sbjct: 405 HDYIGDKDFKKGMNMYLTK---FQQKNAATEDLWESL-ENASGKPIAAVMNTWTKQMGFP 460
Query: 472 IISVNT----DTERTTLEQHRFLLEKTDV-EDIP-YHIPLFAVQSSGEDDTKNGLFTDR- 524
+I V D L Q +F + V ED P + +P+ S + K + D+
Sbjct: 461 LIYVEAEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKP 520
Query: 525 ----TLKLSEPE--LIVNSGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFIDLR 578
LK +P+ + +N G G YR Y + L+ +++ + +D + DL
Sbjct: 521 EMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLL-PGIRDLSLPPVDRLGLQNDLF 579
Query: 579 SLIGSEYQKKIHIDGVLMILRCLASHVDLTEELYRGLSIGLDILQTIENALRTYTGKSEK 638
SL + + VL ++ + + T ++ LS L IL T+ + Y E
Sbjct: 580 SLARAGIISTVE---VLKVMEAFVNEPNYT--VWSDLSCNLGILSTLLSHTDFYEEIQE- 633
Query: 639 AFITDIYVPLWDKFSWN 655
F+ D++ P+ ++ W+
Sbjct: 634 -FVKDVFSPIGERLGWD 649
>SPBC1921.05 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 882
Score = 189 bits (479), Expect = 2e-47
Identities = 191/797 (23%), Positives = 353/797 (43%), Gaps = 73/797 (9%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDK 64
L + V P+ Y L L D + + G++ V L + S + + L S
Sbjct: 20 LPKNVKPIHYDLSLYPDLETFTYGGKVVVTLDVLEDSNSITLHGINLRILTAALEWGSQT 79
Query: 65 PLS--ISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMS 122
+ +SY + F S P N A L + + ++++ G ++++++
Sbjct: 80 VWASEVSYGDERIVLQFPSTVPAN---SVAVLTLPFTARISSGME------GFYRSSYV- 129
Query: 123 DTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVT 182
D+ G + Y+ T +P AR FPC+DEP K + + +TA + + ++SN + +V
Sbjct: 130 DSDG-NTKYLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNMNAVEETVK 188
Query: 183 DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKN-KTIPVQLFAPQSISH-ATYSF 240
D K +F++T M+T + + +LE++ K+ +PV+++ S ++
Sbjct: 189 DGLKT-ARFAETCRMSTYLLAWIVAELEYVEYFTPGKHCPRLPVRVYTTPGFSEQGKFAA 247
Query: 241 DTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPS 300
+ + L G YPL K D+V +P AMENWGL+T+++ +L++ + + +
Sbjct: 248 ELGAKTLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILVSEDSAA--T 305
Query: 301 VIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFAT---WFACDLLDEHDNDGYWSSD 357
VI++V +++ HEL HQW GN ++ WD LW NE FAT WF+C+ + W S
Sbjct: 306 VIERVAEVVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNHF--YPEWKVWES- 362
Query: 358 VYLT-QMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVG 416
Y+T +++ +S DA ++ I + + + F+ Y KG ++R + + VG
Sbjct: 363 -YVTDNLQSALSLDALRSSHPIE----VPIMHDYEINQIFDAISYSKGSCVIRMVSKYVG 417
Query: 417 KENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVN 476
++ F + + + S+ + T + D++ + ++I++ +WT+ G P++SV+
Sbjct: 418 EDTFIKGIQKYISK-HRYGNTVTE--DLWAAL-SAESGQDISSTMHNWTKKTGYPVLSVS 473
Query: 477 -TDTERTTLEQHRFLLE---KTDVEDIPYHIPL-FAVQSSGEDDT-KNGLFTDRTLKLS- 529
T+ +EQHRFL K + + + Y PL G+ + + +DR+ K+
Sbjct: 474 ETNDGELLIEQHRFLSTGDVKPEEDTVIYWAPLKLKTMKDGKAVVDEKAVLSDRSKKIKV 533
Query: 530 EPELI----VNSGARGLYRVSYETDKCYELINEAL-KNSKISDLDLFKIFIDLRSLIGSE 584
+ E + +NS G+YRV+Y D +L A+ K +S D + D+ SL +
Sbjct: 534 DKEALESYKLNSEQSGIYRVNYSADHLKKLSQIAVEKPDYLSVEDRAGLIADVASLSRAG 593
Query: 585 YQKKIHIDGVLMILRCLASHVDLTEELYRGLSIGLDILQTIENALRTYTG---KSEKAFI 641
Y K ++ + + V E L R L I++ LR + + K +
Sbjct: 594 YGKVSSTLDLIKTWKDEPNFVVFAEMLAR--------LNGIKSTLRFESSDIIAAMKKLV 645
Query: 642 TDIYVPLWDKFSW----NDFHVSSYQLKVMSKVMFGIKHLDSTLTVANQLMKKILSGPNK 697
++ W ND H+ Q K G+ D + A SG
Sbjct: 646 LEVSATKAHSLGWEFKANDDHIIR-QFKSTVYNYAGLFGDDKVVKDALSKFDAYASGNKS 704
Query: 698 SIPLELCGSVFATVSCHQKNVKQWKKLYELVKSAKGVESHVDGGSSIDIQNMALENLAFN 757
+I L +VF ++ K W +L E+ + ++N L
Sbjct: 705 AINDNLRSAVF-NIAIRYGGAKSWDQLLEIYTKT----------NDPYVRNSCLRAFGVT 753
Query: 758 TNEELIKKTLNFILTNI 774
+E+ I+KTL+ L I
Sbjct: 754 EDEKYIQKTLDLTLDPI 770
>Hs5031881 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1025
Score = 188 bits (477), Expect = 4e-47
Identities = 163/607 (26%), Positives = 277/607 (44%), Gaps = 59/607 (9%)
Query: 3 LSLTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQ---------PGQSFNKFKFHCKQ 53
+ L VVPL Y L L+ + F+G +T+ ++ Q G + ++ F
Sbjct: 166 IRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTF---- 221
Query: 54 LIVTKVLLSDKPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTT 113
++ V +K I A ++ + + L +A L+I Y +++
Sbjct: 222 --MSAVSSQEKQAEILEYAYHGQIAIVAPEAL-LAGHNYTLKIEYSANISSSYY------ 272
Query: 114 GLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISN 173
G + ++ ++ Y AT +P+ ARS FPCFDEP K + + + D+++ +SN
Sbjct: 273 GFYGFSYTDESN--EKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSN 330
Query: 174 TSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSI 233
++ V DD +FS++ M+T F +G+++ L DV N T+ P++I
Sbjct: 331 MPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDV---NGTLVSIYAVPENI 387
Query: 234 SHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTP 293
Y+ +T V+LL + + YPL+KLD+V +P AMENWGLLTF+ LL
Sbjct: 388 GQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFR-EETLLYD 446
Query: 294 QALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGY 353
S + + V ++I HEL HQW GN ++ W+ LW NE FAT+ L++ +
Sbjct: 447 SNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKE-L 505
Query: 354 WSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQ 413
S + +L + D+ ++ I+ V+S + + F+ Y KG SLL L+
Sbjct: 506 SSYEDFLDARFKTMKKDSLNSSHPISS----SVQSSEQIEEMFDSLSYFKGSSLLLMLKT 561
Query: 414 SVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEIL-KSENIANFYSSWTRTPGIPI 472
+ ++ F A+ S I+ D++ E+ ++ ++ +WT G P+
Sbjct: 562 YLSEDVFQHAVVLYLHNHS---YASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPL 618
Query: 473 ISVNTDTERTTLEQHRFLLE-KTDVE--DIPY--HIPLFAV---------QSSGEDDTKN 518
++V + ++Q RF L K +++ D Y HIPL V QS D K+
Sbjct: 619 VTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSKYQSVSLLDKKS 678
Query: 519 GLFTDRTLKLSEPEL--IVNSGARGLYRVSYETDKCYELINEALKNSKI-SDLDLFKIFI 575
G+ + L+E L VN G Y V Y D LI++ N + SD D +
Sbjct: 679 GV-----INLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLIN 733
Query: 576 DLRSLIG 582
++ L G
Sbjct: 734 NIFELAG 740
>7292091 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 866
Score = 184 bits (468), Expect = 4e-46
Identities = 156/657 (23%), Positives = 290/657 (43%), Gaps = 91/657 (13%)
Query: 9 VVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFN-----------KFKFHCKQLIVT 57
VVP Y L L + K+ F G+ VQ+ ++P + F C +L
Sbjct: 14 VVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDSVELHFECSKL--- 70
Query: 58 KVLLSDKPLSISYDANEQTVS--FSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGL 115
KP I Y A +T + F+ + P A+ L +S+ G++N + G
Sbjct: 71 ------KPEKIVYSAENETATLEFAQEIP---AETQGVLHMSFTGELN------DKMKGF 115
Query: 116 FKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTS 175
+++ + + + T + AR FPC+DEP K + +TL +SN
Sbjct: 116 YRSKYFGPNG--EERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMP 173
Query: 176 VENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSI-S 234
V D + V+F +TP+M+T +G+ +++ + + V++F P
Sbjct: 174 VIKEDSLPDGLRRVRFDRTPIMSTYLVAVVVGEYDYVEGK---SDDGVLVRVFTPVGKRE 230
Query: 235 HATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQ 294
T++ + ++LP + + YPL K+D++ + S AMENWGL+T++ +L+ P+
Sbjct: 231 QGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPK 290
Query: 295 ALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATW--FAC--DLLDEHDN 350
S Q + + HE+ HQW GN ++ + W HLW NE +A++ F C L E+D
Sbjct: 291 NTSLMRK-QSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDI 349
Query: 351 DGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRS 410
+ +D+Y +E ++ + S ID + F+ Y+KG S++R
Sbjct: 350 WTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEID--------EIFDEISYNKGASVIRM 401
Query: 411 LQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGI 470
L +G++ F + + ++ + TC + D++ + E S+N+++ +SWT+ G
Sbjct: 402 LHDYIGEDTFRKGM-NLYLTRHQYGNTCTE--DLWAALQE-ASSKNVSDVMTSWTQHKGF 457
Query: 471 PIISVNTDTERTT-------LEQHRFLLEKTDV-EDIPYHIPLFAVQSSGEDDTKNGLFT 522
P++SV ++E+T+ L+Q +F + + E+ + +P+ S
Sbjct: 458 PVVSV--ESEQTSKNQRLLRLKQCKFTADGSQADENCLWVVPISVSTSKNPTGIAKTFLL 515
Query: 523 DRTL------KLSEPELI-VNSGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFI 575
D++ + E + I +N G G YR Y + +L+ A++ ++ LD +
Sbjct: 516 DKSSMEVTLDNVDEDDWIKINPGTVGYYRTRYSQEMLEQLM-PAVEKMELPPLDRLGLID 574
Query: 576 DLRSLI-------------------GSEYQKKIHIDGVLMILRCLASHVDLTEELYR 613
D+ +++ + Y I L L L SH DL E+ +R
Sbjct: 575 DMFAMVQAGHASTADVLALVDSYRNETNYTVWTAITNSLTNLHILISHTDLMEDFHR 631
>Hs20534524 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 957
Score = 180 bits (456), Expect = 1e-44
Identities = 180/706 (25%), Positives = 304/706 (42%), Gaps = 68/706 (9%)
Query: 132 ILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKF 191
I+AT +P AR FPCFDEPN K Y +++T ++ +SN V DD+ F
Sbjct: 217 IVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTF 276
Query: 192 SKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHATYSFDTIVELLPIV 250
K+ M+T F + + ++ ++ N P+ ++ P+ A Y+ + +
Sbjct: 277 EKSVPMSTYLVCFAVHQFDSVK---RISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYF 333
Query: 251 EKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIV 310
E+ ++Y L KLD + +P AMENWGL+T++ +LL P+ S S Q+V ++
Sbjct: 334 EEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKE-SASSNQQRVATVVA 392
Query: 311 HELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVISTD 370
HEL HQW GN ++ D W+ LW NE FA++F ++ + D + L + V D
Sbjct: 393 HELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDD 452
Query: 371 AEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIFSE 430
+ +++ I ++ V + + F+ Y KG S+LR L+ + ENF + Q++ E
Sbjct: 453 SLMSSHPI----IVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKG-CQMYLE 507
Query: 431 SSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTERTTLEQHRFL 490
F K D + + E + + +WTR G P+++VN T Q RFL
Sbjct: 508 KYQFKNA--KTSDFWAALEEASRLP-VKEVMDTWTRQMGYPVLNVNGVKNIT---QKRFL 561
Query: 491 LEKTDVEDIP-------YHIPLFAVQSSGEDDTKNGLFTDR-----TLKLSEPE----LI 534
L+ P ++IP V+ + ++ T + LF TL S P L
Sbjct: 562 LDPRANPSQPPSDLGYTWNIP---VKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLK 618
Query: 535 VNSGARGLYRVSYETDKCYELINE-ALKNSKISDLDLFKIFIDLRSLIGSEYQKKIHIDG 593
+N G YRV+YE + +L + S D + D +L ++ +
Sbjct: 619 INPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQL---LDYKV 675
Query: 594 VLMILRCLASHVDLTEELYRGLSIGLDILQTIENALRTYTGKSEKAFITDIYVPLWDKFS 653
L + + L + R +S I+ E+ Y E + P+ D
Sbjct: 676 ALNLTKYLKREENFL-PWQRVISAVTYIISMFEDDKELYPMIEE--YFQGQVKPIADSLG 732
Query: 654 WNDFHVSSYQLKVMSKVMFGIKHLD-STLTVANQLMKKILSGPNKSIPLELCGSVFATVS 712
WND +L S + F K D L A+ L ++ L+G S+P+ L V+
Sbjct: 733 WNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNG-TVSLPVNLRLLVYRYGM 791
Query: 713 CHQKNVKQWK---KLYELVKSAKGVESHVDGGSSIDIQNMALENLAFNTNEELIKKTLNF 769
+ N W + Y+ A+ E + G +S ++N+ L + +L+K T N
Sbjct: 792 QNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLAS--VKNVTL----LSRYLDLLKDT-NL 844
Query: 770 ILTNITSTSVENALFGLNYNFREPLDGKKNKLVRDVCWEWFELNYD 815
I T T + + N +++ W W +LN+D
Sbjct: 845 IKTQDVFTVIRYISY--------------NSYGKNMAWNWIQLNWD 876
>Hs4503575 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 957
Score = 179 bits (454), Expect = 2e-44
Identities = 180/706 (25%), Positives = 303/706 (42%), Gaps = 68/706 (9%)
Query: 132 ILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKF 191
I AT +P AR FPCFDEPN K Y +++T ++ +SN V DD+ F
Sbjct: 217 IAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTF 276
Query: 192 SKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHATYSFDTIVELLPIV 250
K+ M+T F + + ++ ++ N P+ ++ P+ A Y+ + +
Sbjct: 277 EKSVPMSTYLVCFAVHQFDSVK---RISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYF 333
Query: 251 EKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIV 310
E+ ++Y L KLD + +P AMENWGL+T++ +LL P+ S S Q+V ++
Sbjct: 334 EEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKE-SASSNQQRVATVVA 392
Query: 311 HELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVISTD 370
HEL HQW GN ++ D W+ LW NE FA++F ++ + D + L + V D
Sbjct: 393 HELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDD 452
Query: 371 AEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIFSE 430
+ +++ I ++ V + + F+ Y KG S+LR L+ + ENF + Q++ E
Sbjct: 453 SLMSSHPI----IVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKG-CQMYLE 507
Query: 431 SSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTERTTLEQHRFL 490
F K D + + E + + +WTR G P+++VN T Q RFL
Sbjct: 508 KYQFKNA--KTSDFWAALEEASRLP-VKEVMDTWTRQMGYPVLNVNGVKNIT---QKRFL 561
Query: 491 LEKTDVEDIP-------YHIPLFAVQSSGEDDTKNGLFTDR-----TLKLSEPE----LI 534
L+ P ++IP V+ + ++ T + LF TL S P L
Sbjct: 562 LDPRANPSQPPSDLGYTWNIP---VKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLK 618
Query: 535 VNSGARGLYRVSYETDKCYELINE-ALKNSKISDLDLFKIFIDLRSLIGSEYQKKIHIDG 593
+N G YRV+YE + +L + S D + D +L ++ +
Sbjct: 619 INPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQL---LDYKV 675
Query: 594 VLMILRCLASHVDLTEELYRGLSIGLDILQTIENALRTYTGKSEKAFITDIYVPLWDKFS 653
L + + L + R +S I+ E+ Y E + P+ D
Sbjct: 676 ALNLTKYLKREENFL-PWQRVISAVTYIISMFEDDKELYPMIEE--YFQGQVKPIADSLG 732
Query: 654 WNDFHVSSYQLKVMSKVMFGIKHLD-STLTVANQLMKKILSGPNKSIPLELCGSVFATVS 712
WND +L S + F K D L A+ L ++ L+G S+P+ L V+
Sbjct: 733 WNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNG-TVSLPVNLRLLVYRYGM 791
Query: 713 CHQKNVKQWK---KLYELVKSAKGVESHVDGGSSIDIQNMALENLAFNTNEELIKKTLNF 769
+ N W + Y+ A+ E + G +S ++N+ L + +L+K T N
Sbjct: 792 QNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLAS--VKNVTL----LSRYLDLLKDT-NL 844
Query: 770 ILTNITSTSVENALFGLNYNFREPLDGKKNKLVRDVCWEWFELNYD 815
I T T + + N +++ W W +LN+D
Sbjct: 845 IKTQDVFTVIRYISY--------------NSYGKNMAWNWIQLNWD 876
>CE21162 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 175 bits (444), Expect = 2e-43
Identities = 156/603 (25%), Positives = 273/603 (44%), Gaps = 67/603 (11%)
Query: 3 LSLTEPVVPLEYTLDLNV---------DHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQ 53
L L V P+ Y L + D F+GQ+ ++L + S K + K
Sbjct: 84 LRLPTSVSPISYQLTVKTYLPGYGYTADKNNLTFEGQVLIELNITK---SIKKVSLNSKD 140
Query: 54 LIVTKVLLSDKPLSISYDANEQTVSFSSDDPLNI-------ADDTAELRISYIGKVNTIK 106
L T+ + + + N ++++F+ DD + D+T E S KV
Sbjct: 141 LNYTEEFIKKSSILV----NGKSIAFTLDDKQSTHEKIFFNLDETVEPTTSATLKVAFGA 196
Query: 107 THRELTTGLFKTNFMSDTTGISDSYILA-THTQPVFARSIFPCFDEPNSKCKYQLTLTAD 165
R +GL++T + T +S + A T +PV+AR + PCFDEP K + +T+
Sbjct: 197 PLRTDMSGLYQTTY---TNSKGESKMAAVTQMEPVYARRMVPCFDEPAYKATWTVTVIHP 253
Query: 166 DKFKVISNTSVENRSVTDDRKQIV--KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTI 223
+K +SN +E++ V D + + F TP M++ I + E+ K +
Sbjct: 254 NKTVAVSN-GIEDK-VEDGQPGFIISTFKPTPRMSSYLLAIFISEFEYNEATTK---SGV 308
Query: 224 PVQLFA-PQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLL 282
++++ P+ + Y+ + V+ L EK + +PL K D+V LP S AMENWGL+
Sbjct: 309 RFRVWSRPEEKNSTMYAVEAGVKCLEYYEKYYNISFPLPKQDMVALPDFSAGAMENWGLI 368
Query: 283 TFQMNHLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFAC 342
T++ + LL P+ S S ++V +I HEL HQW GN ++ W+ LW NE FAT
Sbjct: 369 TYRESALLYDPRIYSG-SQKRRVAVVIAHELAHQWFGNLVTLKWWNDLWLNEGFATLVEY 427
Query: 343 DLLDEHDNDGYWSSDVYLTQ--MENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHI 400
DE +DG + T + + ++ D+ +T +T + D+F+
Sbjct: 428 LGTDE-ISDGNMRMREWFTMDALWSALAADSVASTHPLT----FKIDKAMEVLDSFDSVT 482
Query: 401 YHKGISLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSE----- 455
Y KG ++L +++++G+ENFN + + + ++ +GE +
Sbjct: 483 YDKGGAVLAMVRKTIGEENFNTGINHYLTRHQFDNADA---GNLLTALGEKIPDSVMGPK 539
Query: 456 ----NIANFYSSWTRTPGIPIISVN-TDTERTTLEQHRFLLEKTDVEDIPYHIPL----- 505
NI+ F WT+ G P+++ + + +EQ RF L T E+ Y P+
Sbjct: 540 GVKLNISEFMDPWTKQLGYPLLNASRINNTHIIVEQSRFKLLATGKEEEKYSNPVWGFKW 599
Query: 506 -----FAVQSSGEDDTKNGLFTDRTLKLSEPELIVNSGARGLYRVSYETDKCYELINEAL 560
+ V S E + K + + S+ +I+N+ + G YR Y + ++ I+E L
Sbjct: 600 DVPVWYQVVGSSELEMKWMKRNEPLIIKSDKNVIINAESNGFYRAGYSSG-LWKEISEML 658
Query: 561 KNS 563
K +
Sbjct: 659 KEN 661
>7301517 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1078
Score = 172 bits (437), Expect = 2e-42
Identities = 202/814 (24%), Positives = 344/814 (41%), Gaps = 78/814 (9%)
Query: 3 LSLTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQR-QPGQSFNKFKFHCKQLIVTKV-- 59
L L E PL Y+L + G LT+++++ S+ + ++ V
Sbjct: 172 LKLYEGWRPLHYSLLIEPSVATSISNGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRV 231
Query: 60 --LLSDKPLSISYDANEQTVSFSSDDP-------LNIADDTA-ELRISYIGKVNTIKTHR 109
L+D S + EQ + F SD +N++ A E ++ + ++ +
Sbjct: 232 IRALAD---GASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVT 288
Query: 110 ELTTGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFK 169
+ G++KT++ + T ++ ++++T PV AR FPCFD P+ K + +++ +FK
Sbjct: 289 DTLQGIYKTSYTNPDTK-NEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFK 347
Query: 170 VISNTSVENRSVTDDRKQIVK-FSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLF 228
+ + ++ S R I F TP M T F + ++ R + T V+++
Sbjct: 348 MALSNMPKSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIW 407
Query: 229 A-PQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMN 287
PQ + Y++ + + LP E G+ L K+D+V +P AMENWGL+TF+ +
Sbjct: 408 TRPQFVGMTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDS 467
Query: 288 HLLLTP--QALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLL 345
LL+ Q S +Q V +I HEL HQW GN ++ WD LW E FA + + L
Sbjct: 468 ALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKAL 527
Query: 346 DEHDNDGYWSSD-VYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKG 404
EH + + S D + + + + + DA+ T+ +I+ DV+S F+P Y KG
Sbjct: 528 -EHAHPEFQSMDTLTMLEFKESMEHDADNTSHAIS----FDVRSTNDVRRIFDPISYSKG 582
Query: 405 ISLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIF-------RRMGEILKSENI 457
LLR L VG F A + + F + D++ G + K ++
Sbjct: 583 TILLRMLNSIVGDVAFRSATRDLLKK---FAYGNMDRDDLWAMLTRHGHEQGTLPKDLSV 639
Query: 458 ANFYSSWTRTPGIPIISVNTDTERTTLEQHRFLLEKTDVED-----IPY----------- 501
SW PG P+++V L Q R+LL + D IP
Sbjct: 640 KQIMDSWITQPGYPVVNVERRGADLVLRQERYLLPSKNTADQSTWFIPITFETDELRKGD 699
Query: 502 HIPLFAVQSSGEDDTKNGLFTDRTLKLSEPELIVNSGARGLYRVSYETDKCYELINEALK 561
+IP ++S E++ G + S+ + +N +G YRV+Y+ L K
Sbjct: 700 NIPTHWMRSEDEEELIVGNVFAHSSN-SDNVIYLNLNRQGYYRVNYDMTSWLAL----KK 754
Query: 562 N-SKISDLDLFKIFIDLRSLIGSEYQKKIHIDGVLMILRCLASHVDLTEELYRGLSIGLD 620
N S + + ++ D L +EY + D L L L VD E L+ GL+
Sbjct: 755 NFSTLPRITRAQLLDDALHLSQAEY---LTYDIPLTFLMELFDAVD-DELLWIAAKPGLN 810
Query: 621 ILQTIENALRTYTGKSEKAFITDIYVPLWDKFSWND-FHVSSYQLKVMSKV-MFGIK-HL 677
L I N R ++ +AF+ I P +D + ++ + S QLK + V F K +
Sbjct: 811 YL--IYNLKREPAYETFRAFMKFIVRPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNY 868
Query: 678 DSTLTVANQLMKKILSGPNKSIPLELCGSVFATVSCHQKNVKQWKKLYELVKSAKGVESH 737
D A ++ + P + SV S + + +W Y+ K+
Sbjct: 869 DRCTQKAQMKFREWMRDPKNNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTT------ 922
Query: 738 VDGGSSIDIQNMALENLAFNTNEELIKKTLNFIL 771
+S + L +L T L+ K LN +
Sbjct: 923 ----TSASEKEEILTSLGCTTKPWLLSKYLNMTI 952
>CE18905 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 747
Score = 172 bits (436), Expect = 2e-42
Identities = 152/554 (27%), Positives = 253/554 (45%), Gaps = 54/554 (9%)
Query: 21 DHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQL-IVTKVLLSDKP-LSISY---DANEQ 75
D + F+G + + L ++ + +K H L I++ SD+ +SIS+ Q
Sbjct: 57 DENKITFEGNVNILLDIKE---TTDKLVLHSSSLNIISATFQSDEQNVSISHWNVQTESQ 113
Query: 76 TVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDTTGISDSYILAT 135
++F ++ + + +A ++I++ GKV T GLF TN + + ++ AT
Sbjct: 114 FLTFYLNNTVKV-QSSAGIQINFQGKVRTDGL------GLFATNSTREDGTVMTNF--AT 164
Query: 136 HTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKTP 195
+ +FAR++ PCFDEP K + ++L +SN +E S +D + + KT
Sbjct: 165 QFETIFARNMIPCFDEPEFKATWNVSLEHPTGSTALSN-GIEVESKVNDDWKTTTYKKTL 223
Query: 196 LMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHATYSFDTIVELLPIVEKRL 254
M++ IGD++F T + N + ++++ P +I ++ + +L E++
Sbjct: 224 KMSSYILALFIGDIQFKET---ILNNGVRIRVYTDPVNIDRVDHALNISRIVLEGFERQF 280
Query: 255 GVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIVHELC 314
G+ YP+EKLD V + AMENWGL+ L+ P V ++++HE+
Sbjct: 281 GIRYPMEKLDFVSVQNFKFGAMENWGLVIHNAYSLIGDPM---------DVTEIVIHEIA 331
Query: 315 HQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVISTDAEVT 374
HQW GN ++ WDH+W NE FA++ L D D Y YL N D V
Sbjct: 332 HQWFGNLVTMKYWDHIWLNEGFASYMTSYGLTFLDPD-YQRDTFYLNCQFNPQINDGGV- 389
Query: 375 TKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIFSESSTF 434
S+ G K+L S + +Y KG S +R L+ G E FN A+ + + E + +
Sbjct: 390 --SLNFG-----KNLSSVMNN-AATVYMKGCSFVRMLENIFGTEYFNEAI-KFYLEKNQY 440
Query: 435 HETCIKPM-DIFRRMGEIL----KSENIANFYSSWTRTPGIPIISVNTDTERTTLEQHRF 489
+ + FR E L K +I F WT G P I V+ D TL Q
Sbjct: 441 DNVDDNDLYEAFRTSSETLDTNGKPFDIEKFARCWTHQNGFPTIQVSNDNGIATLTQSHL 500
Query: 490 LLEKTDVEDIPY--HIPLFAVQSSGEDDTKNGLFTDRTLKL---SEPELIVNSGARGLYR 544
+ + + Y IP++ Q GE + + L ++ +I+N+ + G Y
Sbjct: 501 YEPQLMLNECDYKWDIPIW-YQEPGEARVQMAWLNRNSTSLELVADDSVIINANSIGYYE 559
Query: 545 VSYETDKCYELINE 558
V Y +DK YE I E
Sbjct: 560 VLY-SDKMYEKIAE 572
>CE10790 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 884
Score = 170 bits (430), Expect = 1e-41
Identities = 136/600 (22%), Positives = 267/600 (43%), Gaps = 60/600 (10%)
Query: 11 PLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDKPLSISY 70
P Y + L+ Q +F G T+ + ++ + + K H + L++ V L +P S
Sbjct: 22 PTHYNVRLSPCLNQFSFDGHATIDVTIKE---ATDVLKVHAQSLLIQSVSLITQPGDAS- 77
Query: 71 DANEQTVSFSSDDPLNIAD---------DTAELRISYIGKVNTIKTHRELTTGLFKTNFM 121
+++ S DD LNI +L ++G++N + G +++ +
Sbjct: 78 ----KSLETSYDDKLNILTIKLPTTMQPQKVQLDFKFVGELN------DKMRGFYRSQY- 126
Query: 122 SDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSV 181
D G ++ ++ +T + +AR FPCFDEP K + +TL ++ +SN +V + +
Sbjct: 127 KDKNG-TEKFLASTQFESTYARYAFPCFDEPIYKATFDVTLEVENHLTALSNMNVISETP 185
Query: 182 T-DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHATYS 239
T D +++ V F+ +P M++ F +G+LE++ K + ++++ P YS
Sbjct: 186 TADGKRKAVTFATSPKMSSYLVAFAVGELEYISAQTK---SGVEMRVYTVPGKKEQGQYS 242
Query: 240 FDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDP 299
D V+ + + + YPL K D++ +P S AMENWGL+T++ LL+ P S
Sbjct: 243 LDLSVKCIDWYNEWFDIKYPLPKCDLIAIPDFSMGAMENWGLVTYREIALLVDPGVTSTR 302
Query: 300 SVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVY 359
+V ++ HEL H W GN ++ W LW E FA++ + + + ++
Sbjct: 303 QK-SRVALVVAHELAHLWFGNLVTMKWWTDLWLKEGFASFMEYMFVGANCPE----FKIW 357
Query: 360 LTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKEN 419
L + + +++ + + +++ + + ++ Y K S+ R L + +
Sbjct: 358 LHFLNDELASGMGLDALRNSHPIEVEIDNPNELDEIYDSITYAKSNSVNRMLCYYLSEPV 417
Query: 420 FNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNT-- 477
F + L F + D++ + E +N+ S WT+ G P++ V+
Sbjct: 418 FQKGLRLYLKR---FQYSNAVTQDLWTALSE-ASGQNVNELMSGWTQQMGFPVLKVSQRQ 473
Query: 478 --DTERTTLEQHRFLLE-KTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLSEPELI 534
+ T+EQ RF+ + D ++ + +P+ S D K LK + E
Sbjct: 474 DGNNRILTVEQRRFISDGGEDPKNSQWQVPITVAVGSSPSDVKARFL----LKEKQQEFT 529
Query: 535 V-----------NSGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFIDLRSLIGS 583
+ NSG G YRV Y + ++ + + + ++ LD F + DL +L+ +
Sbjct: 530 IEGVAPGEWVKLNSGTTGFYRVEYSDEMLTAMLPD-IASRRMPVLDRFGLINDLSALLNT 588
>7299744 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 167 bits (424), Expect = 5e-41
Identities = 182/807 (22%), Positives = 353/807 (43%), Gaps = 71/807 (8%)
Query: 11 PLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSD------K 64
P Y L L + + F GQ T+ + + + ++ H L ++ V + + +
Sbjct: 129 PTHYDLYLFPNIETGEFSGQETITITVEE---ATDQIVLHSLNLNISSVSIMNTGSDTLE 185
Query: 65 PLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDT 124
L + DA + + F ++PL T L I + G + GL+ ++++ +
Sbjct: 186 ILETTVDAVREFLIFQLNEPLT-KGRTVRLHIGFEGSM------ANKIVGLYSSSYVKED 238
Query: 125 TGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLT--ADDKFKVISNTSVENRSVT 182
+ +I + +P +AR FPCFDEP K ++ +TL + + + +SN +V++ SV+
Sbjct: 239 E--TRKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDS-SVS 295
Query: 183 DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKN--KTIPVQLFA-PQSISHATYS 239
Q V F+K+ M+T F + D + + + K +T + ++A P+ + +
Sbjct: 296 QGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLA 355
Query: 240 FDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDP 299
++ + YPL KLD+ +P AME+WGL+T++ LL +A S
Sbjct: 356 VTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYD-EATSSA 414
Query: 300 SVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVY 359
+ Q++ +I HE H W GN ++ + W+ LW NE FA++ + L W
Sbjct: 415 TNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASF--VEYLGVDAVYPEWK---- 468
Query: 360 LTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKEN 419
+ +V++ D + + I Q V++ ++ F+ Y KG SL+R L+ +G+
Sbjct: 469 MASAPSVLTLDGTLGSHPIIQ----TVENPDQITEIFDTITYSKGSSLVRMLEDFLGETT 524
Query: 420 FNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVN--T 477
F +A+ +E + + + + F + ++ N+ +WT G+P++++ +
Sbjct: 525 FRQAVTNYLNE---YKYSTAETGNFFTEIDKLELGYNVTEIMLTWTVQMGLPVVTIEKVS 581
Query: 478 DTERTTLEQHRFLLEKTDVE--------DIPYHIPLFAVQSSGEDDTKNGLFTDRT-LKL 528
DTE L Q RFL D + + + IP+ SS + + D++ + +
Sbjct: 582 DTE-YKLTQKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFYHDQSEITV 640
Query: 529 SEPELI----VNSGARGLYRVSYETDKCYELINE-ALKNSKISDLDLFKIFIDLRSLIGS 583
+ P + N+ G YRV+Y+TD +L ++ ++ S +D + D +L S
Sbjct: 641 TVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALADS 700
Query: 584 EYQKKIHIDGVLMILRCLASHVDLTEELYRGLSIGLDILQTIENAL-RTYTGKSEKAFIT 642
++ + R L D Y S+ L +++ L T T K + T
Sbjct: 701 ---TQLPYATAFELTRYLDKETD-----YVPWSVAASRLTSLKRTLYYTSTYAKYKKYAT 752
Query: 643 DIYVPLWDKFSW--NDFHVSSYQLKVMSKVMFGIKHLDSTLTVANQLMKKILSGPNKSIP 700
+ P++ +W + H+ + +L+V + L+S LT A + L+ P
Sbjct: 753 ALIEPIYTALTWTVGEDHLDN-RLRVTALSAACSLGLESCLTEAGEQFNAWLAKPEDRPK 811
Query: 701 LELCGSVFATVSCHQKNVKQWKKLYELV---KSAKGVESHVDGGSSIDIQNMALENLAFN 757
++ +V+ + + W ++EL A + G S+I I + +
Sbjct: 812 ADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLA 871
Query: 758 TNEELIKKTLNF-ILTNITSTSVENAL 783
NEE ++ F LT I++ V +L
Sbjct: 872 WNEEYVRGQDYFTCLTYISANPVGESL 898
>Hs20149637 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 948
Score = 165 bits (417), Expect = 3e-40
Identities = 174/764 (22%), Positives = 315/764 (40%), Gaps = 70/764 (9%)
Query: 3 LSLTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTK---- 58
+ L E V+P+ Y L ++ + F G V++ QP + H + T
Sbjct: 52 IRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGA 111
Query: 59 -VLLSDKPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFK 117
LS++PL + ++ ++ + +PL + + I Y G ++ E G +K
Sbjct: 112 GERLSEEPLQVLEHPPQEQIALLAPEPLLVGLPYTVV-IHYAGNLS------ETFHGFYK 164
Query: 118 TNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVE 177
+ + + + + +T +P AR FPCFDEP K + + + + + ISN +
Sbjct: 165 STYRTKEGELR--ILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLV 222
Query: 178 NRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHA 236
+ F T M+T F I D E + K+ + V ++A P I+ A
Sbjct: 223 KSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVS---KITKSGVKVSVYAVPDKINQA 279
Query: 237 TYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQAL 296
Y+ D V LL E + YPL K D+ +P AMENWGL T++ + LL +
Sbjct: 280 DYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKS 339
Query: 297 SDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSS 356
S S + + + HEL HQW GN ++ + W+ LW NE FA + + +
Sbjct: 340 SASSKL-GITVTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSV-THPELKVG 397
Query: 357 DVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVG 416
D + + + + DA ++ ++ V++ + F+ Y KG +L L++ +
Sbjct: 398 DYFFGKCFDAMEVDALNSSHPVS----TPVENPAQIREMFDDVSYDKGACILNMLREYLS 453
Query: 417 KENFNRALAQIFSESS-----------TFHETC----IKPMDIFRRMGEILKSE------ 455
+ F + Q + S + C +K MD F + S
Sbjct: 454 ADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQE 513
Query: 456 --NIANFYSSWTRTPGIPIISVNTDTERTTLEQHRFLLEKTDVEDIPY--HIPLFAVQSS 511
++ ++WT G P+I++ ++Q ++ D Y H+PL + +S
Sbjct: 514 GVDVKTMMNTWTLQRGFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFI-TS 572
Query: 512 GEDDTKNGLFTDRTLKLSEPELI----VNSGARGLYRVSYETDKCYELINEALKNSKISD 567
+ L +T L PE + N G G Y V YE D ++ + LK + +
Sbjct: 573 KSNMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDG-WDSLTGLLKGTHTAV 631
Query: 568 LDLFKIFIDLRSLIGSEYQ----KKIHIDGVLMILRCLASHVDLTEELYRGLSIGLDILQ 623
D SLI + +Q K+ I+ L + L ++ +++GL+ + + +
Sbjct: 632 SS-----NDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIM-PVFQGLNELIPMYK 685
Query: 624 TIENALRTYTGKSEKAFITDIYVPLWDKFSWND-FHVSSYQLKVMSKVMFGIKHLDSTLT 682
+E KAF+ + L DK +W D VS L+ ++ + + +
Sbjct: 686 LMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSEQMLRSELLLLACVHNYQPCVQ 745
Query: 683 VANQLMKKIL-SGPNKSIPLELCGSVFATVSCHQKNVKQWKKLY 725
A +K S N S+P+++ +VFA + ++ + W LY
Sbjct: 746 RAEGYFRKWKESNGNLSLPVDVTLAVFAVGA---QSTEGWDFLY 786
>CE24087 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 781
Score = 160 bits (406), Expect = 6e-39
Identities = 156/719 (21%), Positives = 302/719 (41%), Gaps = 94/719 (13%)
Query: 134 ATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQ-IVK-- 190
AT +P FAR + PCFDEPN K +Q+ + + SN ++ ++ + K ++K
Sbjct: 20 ATQFEPTFARKMLPCFDEPNFKATFQVAIIRNPHHIARSNMNI---LISKEYKNGLIKDV 76
Query: 191 FSKTPLMNTSYFGFCIGD-LEFLRTDVKLKNKTIPVQLFAPQSI--SHATYSFDTIVELL 247
F K+ M+T + D +++ + K I V+L+APQ + + + DT + L
Sbjct: 77 FEKSVKMSTYLLAVAVLDGYGYIKRLTRNTQKAIEVRLYAPQDMLTGQSEFGLDTTIRAL 136
Query: 248 PIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQ 307
E + YPL+K+D++ L S+ AMENWGL+TF+ + LL + S + + +
Sbjct: 137 EFFEDYFNISYPLDKIDLLALDDFSEGAMENWGLVTFRDSALLFNERKASVVAK-EHIAL 195
Query: 308 LIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVI 367
+I HE+ HQW GN ++ D W+ ++ NE FA + ++ D S Y +
Sbjct: 196 IICHEIAHQWFGNLVTMDWWNEVFLNEGFANYMEYKCVEHLFPDWSIMSRFYAENLAFSQ 255
Query: 368 STDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQI 427
D +++++I D SL + DA YHK +++ + + G++NF AL +
Sbjct: 256 EPDGFLSSRAIESD---DDDSLLNLFDAIN---YHKAAAIIHMIAEMAGQKNFQNALVEY 309
Query: 428 FSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISV-NTDTERTTLEQ 486
++ + + + I + + + +I + ++T G P+++V TD Q
Sbjct: 310 LNKYAYSNAIGVDLWKIVEKHANLQGTVSIPDLAKAYTTQVGYPLLTVERTDEGVLVHNQ 369
Query: 487 HRFLLEKTDVE-----DIPYHIPLFAVQSSGEDDTKNGLFTD----RTLKLSEPELIVNS 537
RFL + D D + IP+ S ++ + D S LI+N+
Sbjct: 370 TRFLFAEGDKAEEKRGDWKWPIPISYRDSEHRRKKQHWIQADDKNVTWETTSNDWLILNT 429
Query: 538 GARGLYRVSYETDKCYELINEALKN-SKISDLDLFKIFIDLRSLIGSEYQKKIHIDGVLM 596
G G ++V Y+ + +L+ + +N + IS +D RS+I
Sbjct: 430 GGVGYFKVLYDPETYRKLVKQLQRNHTTISPID--------RSMI--------------- 466
Query: 597 ILRCLASHVDLTEELYRGLSIGLDILQTIE------------NALRTYTGKSEKAFITDI 644
L DL++ +S+ D+L+ +E LRT E++ DI
Sbjct: 467 ----LVDSFDLSKTSLLNISVYFDLLEYVEKETDKMTWSIVGKQLRTIEALIEESDYLDI 522
Query: 645 Y--------VPLWDKFSWNDFHVSSYQLKVMSKVMFGIKHLDSTLTVANQLMKKILSGPN 696
Y + L++ W++ + Q ++ + F + Q ++ L +
Sbjct: 523 YQDFQRSLIMRLYESLDWDEQGANPNQKRLQVDI-FAVACRLQIKDCTKQAYQRYLQWVS 581
Query: 697 KSIPLELCGSVFATVSCHQKNVKQWKKLYELVKSAKGVESHVDGGSSIDIQNMALENLAF 756
+ + Q W+++++ K+A +S +N + L
Sbjct: 582 SGVRNPEHHMIALMEGVKQGETTAWERIWKAYKTA----------TSPSEKNNIIGALTS 631
Query: 757 NTNEELIKKTLNFILTNITSTSVENALFGLNYNFREPLDGKKNKLVRDVCWEWFELNYD 815
+ LI + L + L ++ +F N+ R++ W++F+ +++
Sbjct: 632 TKDASLINRLLKYCLDGKIKANLIPRVFSY---------FSLNQSTRNIVWKFFKTHFE 681
>Hs7019561 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1024
Score = 160 bits (405), Expect = 8e-39
Identities = 208/863 (24%), Positives = 354/863 (40%), Gaps = 89/863 (10%)
Query: 3 LSLTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLS 62
L L+ + PL Y L L + F G++ V++ R + H ++ V KV L+
Sbjct: 139 LRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRN---ATRYVVLHASRVAVEKVQLA 195
Query: 63 DKPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMS 122
+ + + + + + + T + + +Y K+ G F+++++
Sbjct: 196 EDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVL 255
Query: 123 DTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVT 182
++ T P AR FPCFDEP K +++++ + +SN VE
Sbjct: 256 HG---ERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFE 312
Query: 183 DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSISHAT--YS 239
+D FS+TPLM+T Y + I + + T K + V+L+A P +I + Y+
Sbjct: 313 EDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTK---SGVVVRLYARPDAIRRGSGDYA 369
Query: 240 FDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDP 299
L+ E V Y L KLD++ +P AMENWGL F +LL P ++S
Sbjct: 370 LHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDP-SVSSI 428
Query: 300 SVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVY 359
S + V +IVHE+CHQW G+ ++ W+ +W E FA +F D +
Sbjct: 429 SYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRF 488
Query: 360 LTQ-MENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKE 418
LT + V+ D ++ ++Q +V F+ Y KG +L+R L +G
Sbjct: 489 LTDVLHEVMLLDGLASSHPVSQ----EVLQATDIDRVFDWIAYKKGAALIRMLANFMGHS 544
Query: 419 NFNRALAQIFSESSTFHE-TCIKPMDIFRRMGEILKSE----NIANFYSSWTRTPGIPII 473
F R L + T H+ D++ + E LK NI WT G P+I
Sbjct: 545 VFQRGL----QDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVI 600
Query: 474 SV--NTDTE-RTTLEQHRFLLE--------KTDVEDIPYHIPLFAVQSSGEDDTKNGLF- 521
++ NT E R + Q F+ + K + IPL V + + +
Sbjct: 601 TILGNTTAENRIIITQQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIW 660
Query: 522 ------TDRTLKLSEPE-LIVNSGARGLYRVSYETDKCYELINEALKNSKI-SDLDLFKI 573
R L + L+ N G +RV+Y+ LI++ ++N ++ S + +
Sbjct: 661 VSNKSEHHRITYLDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGL 720
Query: 574 FIDLRSLIGSEYQKKIHIDGVLMILRCLASHVDLTEELYRGLSIGLDILQTIENALRTYT 633
D SL + Y + + L I+R L+ D + S L L + + + Y
Sbjct: 721 IDDAFSLARAGYLPQ---NIPLEIIRYLSEEKDFLP--WHAASRALYPLDKLLDRMENYN 775
Query: 634 GKSEKAF--ITDIYVPL-WDKFSWNDFHV-SSYQLK------VMSKVMFGIKHLDSTLTV 683
+E + Y+ L W K ++N V +SYQ + +M FG KH
Sbjct: 776 IFNEYILKQVATTYIKLGWPKNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQ--- 832
Query: 684 ANQLMKKILSGPNKSIPLELCGSVFAT-VSCHQKNVKQWKKLYELVKSAKGVESHVDGGS 742
A+ L+ +S IPL + V+ T VS ++V W+ ++ S V
Sbjct: 833 ASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDV--WEFIWMKFHSTTAVSE------ 884
Query: 743 SIDIQNMALENLAFNTNEELIKKTLNFILTNITSTSVENALFGLNYNFREPLDGKKNKLV 802
+ + LE L + + L+ + LN L N ++A+ + + R P
Sbjct: 885 ----KKILLEALTCSDDRNLLNRLLNLSL-NSEVVLDQDAIDVIIHVARNPHG------- 932
Query: 803 RDVCWEWFELNYDLWGRKSLREG 825
RD+ W++F D W + R G
Sbjct: 933 RDLAWKFFR---DKWKILNTRYG 952
>7301772 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 932
Score = 157 bits (396), Expect = 9e-38
Identities = 137/505 (27%), Positives = 234/505 (46%), Gaps = 48/505 (9%)
Query: 87 IADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDTTGISDSYILATHTQPVFARSIF 146
+A +T EL + + +N R+L G +++++ ++ +I T +P AR F
Sbjct: 126 LAGNTYELYMPFAADLN-----RQLE-GYYRSSYKDPVANLT-KWISVTQFEPASARLAF 178
Query: 147 PCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIV--KFSKTPLMNTSYFGF 204
PCFDEP+ K + +TL K+ ISN + + + +F ++ M+T +
Sbjct: 179 PCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAY 238
Query: 205 CIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLD 264
+ D F L N + P +I Y+ ++L E+ G+ +PL K+D
Sbjct: 239 SVND--FSHKPSTLPNSALFRTWARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKID 296
Query: 265 VVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISF 324
+ +P S AMENWGL+T++ LL + A S + Q+V ++ HEL HQW GN ++
Sbjct: 297 QIAVPDFSAGAMENWGLVTYREIALLYSA-AHSSLADKQRVASVVAHELAHQWFGNLVTM 355
Query: 325 DSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVI 384
W LW NE FAT+ A ++ + + L+ + + DA ++ I++
Sbjct: 356 KWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISR---- 411
Query: 385 DVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFN---RALAQIFS----ESSTFHET 437
++ + S++F+ Y KG ++LR + +G+E+F +A Q FS E E+
Sbjct: 412 PIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWES 471
Query: 438 CIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTERTT--LEQHRFLLEKTD 495
+ +R + KS +I + SWT G P+I+V D T L Q R+LL T
Sbjct: 472 LTQAAHKYR---SLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLL-NTQ 527
Query: 496 VED--------IPYHIPLFAVQSSGE-------DDTKNGLFTDRTLK-LSEPE--LIVNS 537
V +P AVQ + KNG +T++ L P+ +I N+
Sbjct: 528 VARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNT 587
Query: 538 GARGLYRVSYETDKCYELINEALKN 562
LY+V+Y+ ++L+ E L N
Sbjct: 588 QLSTLYKVNYDAQN-WKLLIETLTN 611
>Hs4502095 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 967
Score = 154 bits (388), Expect = 8e-37
Identities = 117/460 (25%), Positives = 206/460 (44%), Gaps = 37/460 (8%)
Query: 114 GLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISN 173
G +++ +M G + T Q AR FPCFDEP K ++ +TL +SN
Sbjct: 192 GFYRSEYME---GNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSN 248
Query: 174 TSVENRSVT---DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA- 229
+ S D + +F TP M+T F + + +++ K + + ++++A
Sbjct: 249 MLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVE---KQASNGVLIRIWAR 305
Query: 230 PQSIS--HATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMN 287
P +I+ H Y+ + +L YPL K D + LP + AMENWGL+T++ N
Sbjct: 306 PSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYREN 365
Query: 288 HLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDE 347
LL P + S S ++V +I HEL HQW GN ++ + W+ LW NE FA++ D
Sbjct: 366 SLLFDPLS-SSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADY 424
Query: 348 HDNDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISL 407
+ + L + V++ DA ++ ++ ++ + S+ F+ Y KG S+
Sbjct: 425 AEPTWNLKDLMVLNDVYRVMAVDALASSHPLST-PASEINTPAQISELFDAISYSKGASV 483
Query: 408 LRSLQQSVGKENFNRALA---QIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSW 464
LR L + ++ F + LA F+ +T + + I + + + W
Sbjct: 484 LRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRW 543
Query: 465 TRTPGIPIISVNTDTERTTLEQHRFLLEKTDVEDIP------YHIPLFAVQSSGEDD--- 515
T G P+I+V+T T TL Q FLL+ P + +P+ +++ +
Sbjct: 544 TLQMGFPVITVDTST--GTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYW 601
Query: 516 -----TKNGLFTDRTLKLSEPELIVNSGARGLYRVSYETD 550
+N LF+ +++N G YRV+Y+ +
Sbjct: 602 LIDVRAQNDLFSTS----GNEWVLLNLNVTGYYRVNYDEE 637
>Hs11641261 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 960
Score = 152 bits (385), Expect = 2e-36
Identities = 156/702 (22%), Positives = 285/702 (40%), Gaps = 75/702 (10%)
Query: 3 LSLTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLS 62
L L V+PL Y L ++ + +F +++ Q H K L +T L
Sbjct: 67 LRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFII---LHSKDLEITNATLQ 123
Query: 63 DKPLS-----------ISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHREL 111
+ S +SY A+EQ + + + Y ++ +
Sbjct: 124 SEEDSRYMKPGKELKVLSYPAHEQIAL--------LVPEKLTPHLKYYVAMDFQAKLGDG 175
Query: 112 TTGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVI 171
G +K+ + T G + T +P AR FPCFDEP K + + + + + +
Sbjct: 176 FEGFYKSTYR--TLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIAL 233
Query: 172 SNTSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-P 230
SN + F T M+T + + D L + + V ++A P
Sbjct: 234 SNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSG---FTSSGVKVSIYASP 290
Query: 231 QSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLL 290
+ Y+ ++LL EK + YPL KLD++ +P + AMENWGL+T++ LL
Sbjct: 291 DKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLL 350
Query: 291 LTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDN 350
P+ S S V ++I HEL HQW GN ++ + W+ +W E FA + ++
Sbjct: 351 FDPKT-SSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYP 409
Query: 351 DGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRS 410
+ + D +L VI+ D+ +++ I++ ++ + F+ Y+KG +L
Sbjct: 410 ELQF-DDYFLNVCFEVITKDSLNSSRPISK----PAETPTQIQEMFDEVSYNKGACILNM 464
Query: 411 LQQSVGKENFNRALAQIFSES-----------STFHETCIK------------PMDIFRR 447
L+ +G+E F + + Q + S+ +C++ P
Sbjct: 465 LKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNM 524
Query: 448 MGEILKSENIANFYSSWTRTPGIPIISVNTDTERTTLEQHRFLLE--------KTDVEDI 499
+ + ++ + ++WT GIP++ V D L+Q RFL + E
Sbjct: 525 LAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERY 584
Query: 500 PYHIPLFAVQSSGEDDTKNGLFTDRTLKLSEPE----LIVNSGARGLYRVSYETDKCYEL 555
+HIPL +S + + +T L PE + N + G Y V YE +L
Sbjct: 585 LWHIPL-TYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQL 643
Query: 556 INEALKN-SKISDLDLFKIFIDLRSLIGSEYQKKIHIDGVLMILRCLASHVDLTEELYRG 614
I + +N + + D + D+ L+G+ ++ +D L + L H + L G
Sbjct: 644 ITQLNQNHTLLRPKDRVGLIHDVFQLVGA---GRLTLDKALDMTYYL-QHETSSPALLEG 699
Query: 615 LSIGLDILQTIENALRTYTGKSEKAFITDIYVPLWDKFSWND 656
LS ++ + ++ K ++ + P+ D+ SW+D
Sbjct: 700 LSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSD 741
>ECU08g0070 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 152 bits (383), Expect = 3e-36
Identities = 140/560 (25%), Positives = 243/560 (43%), Gaps = 48/560 (8%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDK 64
L+ VVP Y DL+V F G + +++ Q V++++L+ K
Sbjct: 30 LSRVVVPEHY--DLHVKILDAGFCGSVGIRVMISQD---------------VSEIVLNAK 72
Query: 65 PLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDT 124
L I DA + + + EL + I ++++ T F ++ +
Sbjct: 73 ELEIR-DAGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYNNGL 131
Query: 125 TGISDS----YILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSV--EN 178
G+ S + +TH +P AR +FPCFD+P+ K +++++ A KF V++NT
Sbjct: 132 VGLYKSGGPKEVYSTHFEPTDARWVFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSL 191
Query: 179 RSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQS-ISHAT 237
R DRK I F +T M+T F +G+L ++ K + ++++ S +
Sbjct: 192 REEYGDRK-IEYFEETCKMSTYLVAFVVGELSYIEDWSK---DGVRLRVYGDSSEVEWGR 247
Query: 238 YSFDTIVELLPIVEKRLGVDYPLE-----KLDVVLLPFLSDMAMENWGLLTFQMNHLLLT 292
Y + L + GV Y K+D+V +P S AMENWGL+TF+ LL
Sbjct: 248 YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYV 307
Query: 293 PQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDG 352
P S+ ++ V + + HEL H W GN ++ WD LW NE FATW + ++ +
Sbjct: 308 P-GKSNVEDMKNVAETVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVV 366
Query: 353 YWS--SDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRS 410
W + L + + D + I ++V + F+ Y KG S++R
Sbjct: 367 SWDVWGEFVLWNVVRGMVDDGLGKSHQIR----MNVTDPGEIGEIFDSISYCKGASVIRM 422
Query: 411 LQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGI 470
+++ VG+ F + + E + M +++ +GE E+I+ W G
Sbjct: 423 IERYVGESVFMLGIRRYIKEHMYGNGNA---MSLWKAIGEEY-GEDISEMVEGWISQAGY 478
Query: 471 PIISVNTDTERTTLEQHRF-LLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLS 529
P++SV L Q R+ +L K+D D + IP+ + + T++
Sbjct: 479 PVVSVQDCGSSLVLSQSRYSMLGKSD--DSLWTIPVVVSWEGKGQERIELRGRETTVRKR 536
Query: 530 EPELIVNSGARGLYRVSYET 549
VN+ G YRV Y++
Sbjct: 537 SSVYKVNAEYGGFYRVLYDS 556
>7299745 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 913
Score = 150 bits (379), Expect = 8e-36
Identities = 132/573 (23%), Positives = 250/573 (43%), Gaps = 40/573 (6%)
Query: 9 VVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDKPLS- 67
+VP Y L + D + NF GQ + +K + + N+ H L +T V + ++ +
Sbjct: 72 LVPTHYELYWHPDLETGNFTGQQRISIKVVE---ATNQIILHSYLLDITSVYVLNREVEK 128
Query: 68 ISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDTTGI 127
+ Q + + + L + D + L I + G++ ++ GL+ + ++++
Sbjct: 129 FELEEERQFLIITLTEELAV-DASITLGIIFGGQM------KDKLVGLYSSTYLNEAGAT 181
Query: 128 SDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLT-ADDKFKVISNTSVENRSVTDDRK 186
I T +P +AR FPCFDEP K + +T+ + +SN + D
Sbjct: 182 RT--ISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYT 239
Query: 187 QIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKN--KTIPVQLFAPQ-SISHATYSFDTI 243
+ + F + M+T + D T VK + +Q +A I+ ++ +
Sbjct: 240 EAI-FETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFG 298
Query: 244 VELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQ 303
+ + V YPL KLD+ +P + AME+WGL+T++ LL P + S + Q
Sbjct: 299 QAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDP-SYSSTANKQ 357
Query: 304 QVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQM 363
+ + HE+ HQW GN ++ W+ LW NE FA + ++ D + +
Sbjct: 358 SIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVAL 417
Query: 364 ENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRA 423
+ V+ DA++++ I Q V+S + F+ Y KG S++R L+ VG E F A
Sbjct: 418 QPVLLYDAKLSSHPIVQ----KVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEA 473
Query: 424 LAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTERT- 482
+ + F+ T D + ++ +I +WT G P+++V+ + +
Sbjct: 474 VTN-YLVKHQFNNTVTD--DFLTEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSF 530
Query: 483 TLEQHRFLLEKTDVEDIP--------YHIPLFAVQSSGEDDTKNGLFTDRTLKLSEPELI 534
+ Q RFL E+ P + +P+ G +++ + ++ ++ P +
Sbjct: 531 KVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVDSVGIAVPSEV 590
Query: 535 ----VNSGARGLYRVSYETDKCYELINEALKNS 563
+N G YRV+YE + + L+ + L S
Sbjct: 591 QWIKLNVNQTGYYRVNYE-ESLWALLIQQLTTS 622
>ECU01g1470 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 150 bits (378), Expect = 1e-35
Identities = 140/560 (25%), Positives = 241/560 (43%), Gaps = 48/560 (8%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDK 64
L+ VVP Y DL+V F G + +++ Q V++++L+ K
Sbjct: 30 LSRVVVPEHY--DLHVKILDAGFCGSVGIRVMISQD---------------VSEIVLNAK 72
Query: 65 PLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDT 124
L I DA + + + EL + I ++++ T F ++ +
Sbjct: 73 ELEIR-DAGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYSNGL 131
Query: 125 TGISDS----YILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSV--EN 178
G+ S + +TH +P AR FPCFD+P+ K +++++ A KF V++NT
Sbjct: 132 VGLYKSGGPKEVYSTHFEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSL 191
Query: 179 RSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQS-ISHAT 237
R DRK I F +T M+T F +G+L ++ K + ++++ S +
Sbjct: 192 REEYGDRK-IEYFEETCKMSTYLVAFVVGELSYIEDWSK---DGVRLRVYGDSSEVEWGR 247
Query: 238 YSFDTIVELLPIVEKRLGVDYPLE-----KLDVVLLPFLSDMAMENWGLLTFQMNHLLLT 292
Y + L + GV Y K+D+V +P S AMENWGL+TF+ LL
Sbjct: 248 YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYV 307
Query: 293 PQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDG 352
P S+ ++ V + HEL H W GN ++ WD LW NE FATW + ++ +
Sbjct: 308 P-GKSNVEDMKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVV 366
Query: 353 YWS--SDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRS 410
W + L + + D + I ++V + F+ Y KG S++R
Sbjct: 367 SWDVWGEFVLWNVVRGMVDDGLGKSHQIR----MNVTDPGEIGEIFDSISYCKGASVIRM 422
Query: 411 LQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGI 470
+++ VG+ F + + E + M +++ +GE E+I+ W G
Sbjct: 423 IERYVGESVFMLGIRRYIKEHMYGNGNA---MSLWKAIGEEY-GEDISEMVEGWISQAGY 478
Query: 471 PIISVNTDTERTTLEQHRF-LLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLS 529
P++SV L Q R+ +L K+D D + IP+ + + T++
Sbjct: 479 PVVSVQDCGSSLVLSQSRYSMLGKSD--DSLWTIPVVVSWEGKGQERIELRGRETTVRKR 536
Query: 530 EPELIVNSGARGLYRVSYET 549
VN+ G YRV Y++
Sbjct: 537 SSVYKVNAEYGGFYRVLYDS 556
>ECU01g0140 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 150 bits (378), Expect = 1e-35
Identities = 140/560 (25%), Positives = 241/560 (43%), Gaps = 48/560 (8%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDK 64
L+ VVP Y DL+V F G + +++ Q V++++L+ K
Sbjct: 30 LSRVVVPEHY--DLHVKILDAGFCGSVGIRVMISQD---------------VSEIVLNAK 72
Query: 65 PLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDT 124
L I DA + + + EL + I ++++ T F ++ +
Sbjct: 73 ELEIR-DAGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYSNGL 131
Query: 125 TGISDS----YILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSV--EN 178
G+ S + +TH +P AR FPCFD+P+ K +++++ A KF V++NT
Sbjct: 132 VGLYKSGGPKEVYSTHFEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSL 191
Query: 179 RSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQS-ISHAT 237
R DRK I F +T M+T F +G+L ++ K + ++++ S +
Sbjct: 192 REEYGDRK-IEYFEETCKMSTYLVAFVVGELSYIEDWSK---DGVRLRVYGDSSEVEWGR 247
Query: 238 YSFDTIVELLPIVEKRLGVDYPLE-----KLDVVLLPFLSDMAMENWGLLTFQMNHLLLT 292
Y + L + GV Y K+D+V +P S AMENWGL+TF+ LL
Sbjct: 248 YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYV 307
Query: 293 PQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDG 352
P S+ ++ V + HEL H W GN ++ WD LW NE FATW + ++ +
Sbjct: 308 P-GKSNVEDMKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVV 366
Query: 353 YWS--SDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRS 410
W + L + + D + I ++V + F+ Y KG S++R
Sbjct: 367 SWDVWGEFVLWNVVRGMVDDGLGKSHQIR----MNVTDPGEIGEIFDSISYCKGASVIRM 422
Query: 411 LQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGI 470
+++ VG+ F + + E + M +++ +GE E+I+ W G
Sbjct: 423 IERYVGESVFMLGIRRYIKEHMYGNGNA---MSLWKAIGEEY-GEDISEMVEGWISQAGY 478
Query: 471 PIISVNTDTERTTLEQHRF-LLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLS 529
P++SV L Q R+ +L K+D D + IP+ + + T++
Sbjct: 479 PVVSVQDCGSSLVLSQSRYSMLGKSD--DSLWTIPVVVSWEGKGQERIELRGRETTVRKR 536
Query: 530 EPELIVNSGARGLYRVSYET 549
VN+ G YRV Y++
Sbjct: 537 SSVYKVNAEYGGFYRVLYDS 556
>7300769 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1646
Score = 146 bits (368), Expect = 2e-34
Identities = 158/688 (22%), Positives = 289/688 (41%), Gaps = 67/688 (9%)
Query: 5 LTEPVVPLEYTLDLNV------DHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTK 58
L E + P+ Y + L +K+ F G++ +++ Q + N H K L +
Sbjct: 43 LAEHITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQ---TTNDIYLHSKNLTYSV 99
Query: 59 VLLSDKPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGL--- 115
KP + AN + S+ + N D +L S NT + TGL
Sbjct: 100 REYWQKPTTEV--ANPTVIQISATNTTNYDTDIVKLTASTALTANTTYILHFVYTGLMED 157
Query: 116 -----FKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKV 170
++++++ D ++ +T Q AR FP FDEP K + +TL F
Sbjct: 158 DMHGFYRSSYVDDNN--VTKWLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNS 215
Query: 171 ISNTS-VENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA 229
+SNT + + T++ + TP M+T F I + V K+ V
Sbjct: 216 VSNTRLISSYPSTEEGIFSDVYKTTPKMSTYLLAFIISEF------VARKDDDFGVYA-R 268
Query: 230 PQSISHATYSFDTIVELLPIVEKRLGVDYPL---EKLDVVLLPFLSDMAMENWGLLTFQM 286
P+ + Y ++ +++L + + L DY +K+D+ +P S AMENWGLLT++
Sbjct: 269 PEYYAQTQYPYNVGIQILEEMGQYLDKDYYSMGNDKMDMAAIPDFSAGAMENWGLLTYRE 328
Query: 287 NHLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLD 346
LL+ A + S Q + ++ HE H W G+ ++ W + W NE FA +F
Sbjct: 329 RSLLVDESATTLASR-QSIAAVVAHEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTA 387
Query: 347 EHDNDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGIS 406
++ + Q+++V++ D+ T ++ + L S F Y+KG +
Sbjct: 388 MVEDKWELEKQFVVDQVQSVMAMDSTNATNPLSDENTYTPAHL---SRMFNSISYNKGAT 444
Query: 407 LLRSLQQSVGKENFNRALAQI---FSESSTFHETCIKPMDIFRRMGEILKSENIANFYSS 463
+R ++ ++G++ F ++L + + S+ E + +E+ + + S
Sbjct: 445 FIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYLLGAWQ--ANWPNSSYNESSKDIFKS 502
Query: 464 WTRTPGIPIISVNTDTERTTLEQHRFLLEKTDVED--IPYHIPLFAVQSSGED------- 514
+T G P+I+V + + Q RFLL+++D D + Y +P+ S +
Sbjct: 503 FTEQVGYPLINVTVGNSQVSFTQKRFLLKESDGSDSSLKYTVPISYTTSETNNFLNTTPK 562
Query: 515 -DTKNGLFTDRTLKLSEPELIVNSGARGLYRVSYETDKCYELINEALKNSK---ISDLDL 570
K + T + ++VN G YRV+Y D + I+ AL + I + +
Sbjct: 563 FILKPNVTTTVQFNSTIKWIVVNIQQTGYYRVTYSDDN-WHAIHHALITANWGGIHENNR 621
Query: 571 FKIFIDLRSLIGSEYQKKIHIDGVLMILRCLASHVDLTEEL----YRGLSIGLD------ 620
+I DL +L + Y V+ L+ +++ T Y + +G D
Sbjct: 622 AQIVDDLFNLARAGYVTYNLTLDVIEYLQTETNYIPWTSAFNGFNYLTIRLGNDTADFNY 681
Query: 621 ILQTIENALRTYTGKSEKAFIT--DIYV 646
+QT+ N G +E + T DIY+
Sbjct: 682 YIQTLTNKAYNQLGFNEASNDTALDIYL 709
Score = 140 bits (354), Expect = 7e-33
Identities = 127/523 (24%), Positives = 229/523 (43%), Gaps = 49/523 (9%)
Query: 9 VVPLEYTLDLNV--DHKQPN-FKGQLTVQLKQRQPGQ-SFNKFKFHCKQLIVTKVLLSD- 63
VVP Y L + V + +P F G++++ L R G + H L +T+ L D
Sbjct: 984 VVPSHYNLTIGVLRNSVEPTIFDGEVSITL--RVVGTLEVQQIILHADTLDITECWLLDA 1041
Query: 64 -----KPLSIS---YDANEQTVSFSSDDPLNIADDTAE---LRISYIGKVNTIKTHRELT 112
+ + IS Y+A Q V PL A + L Y G + T
Sbjct: 1042 AGAQVEAIDISRLIYEAATQQVRV----PLTEAAQPGKNYTLGFKYTGHIRTDMA----- 1092
Query: 113 TGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVIS 172
G F +++ T ++ ++ T Q + AR + PCFDEP K ++QL + + ++ I+
Sbjct: 1093 -GFFSASYVERDTNVT-RWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIA 1150
Query: 173 NTSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQS 232
NT ++ + + F +TP+M+T F + + N++ L P+
Sbjct: 1151 NTKLKETKALSQDRFVDHFKETPVMSTYLLAFMVANYS------ARGNESEFAVLTRPEF 1204
Query: 233 ISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLL---PFLSDMAMENWGLLTFQMNHL 289
+ +S+ +++ + Y DV+ P MENWGL+ + + L
Sbjct: 1205 YDNTEFSYHVGQQVVSAYGELFQSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVL 1264
Query: 290 LLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHD 349
+ P D S + ++I HE H W G+ ++F W + W NEAFA ++ + +
Sbjct: 1265 IQEPGYSDDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLY 1324
Query: 350 NDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLR 409
D + + QM+ + TDA+ T+ +T ++++ + F Y KG ++R
Sbjct: 1325 PDYHLDEQFVVRQMQLIFGTDAQNGTQPMTSPE-SEIQTPSQIAYKFSGIAYAKGACIVR 1383
Query: 410 SLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEIL---KSENIANFYSSWTR 466
+ +G ENF+ A+ + +H T P ++F + E + ++ +F + +T
Sbjct: 1384 MWRNLMGAENFDTAIRSYLQQ---YHLTNTVPYNLFYHLFEHWPKNQDVDLVDFLTDYTE 1440
Query: 467 TPGIPIISVNT--DTERTTLEQHRFLLEKTDVED--IPYHIPL 505
G P+I V + T+EQ RFLL K D + + Y +P+
Sbjct: 1441 QVGYPMIIVKALQGNKVVTVEQSRFLLNKDDGSNATLKYTVPI 1483
>7301771 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1082
Score = 144 bits (364), Expect = 5e-34
Identities = 103/390 (26%), Positives = 180/390 (45%), Gaps = 26/390 (6%)
Query: 114 GLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISN 173
G +++++ T ++ AT +P AR FPCFDEP K + +TL +F +SN
Sbjct: 142 GYYRSSYKDPVTN-KTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSN 200
Query: 174 TSVENRSVTDDRKQIV--KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQ 231
V + + +F ++ M+T + + D F + L N + P
Sbjct: 201 MPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPST--LPNGALFRTWARPN 258
Query: 232 SISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLL 291
+I Y+ + ++L E+ G+ YPL K+D + +P S AMENWGL+ ++ + LL
Sbjct: 259 AIDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLY 318
Query: 292 TP--QALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHD 349
+P +L+D Q + +I HEL HQW GN ++ W LW NE FAT+ A + E
Sbjct: 319 SPTHSSLADK---QDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIY 375
Query: 350 NDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLR 409
+ + LT + D+ V++ I++ ++ + ++F+ Y KG ++LR
Sbjct: 376 PEWHSRDKGSLTALMTAFRLDSLVSSHPISR----PIQMVTEIEESFDAISYQKGSAVLR 431
Query: 410 SLQQSVGKENFNRALAQIF-------SESSTFHETCIKPMDIFRRMGEILKSENIANFYS 462
+ +G+E+F L + +E + E+ + G + +I
Sbjct: 432 MMHLFMGEESFRTGLREYLKLYAYKNAEQNNLWESLTTAA---HQNGALPGHYDINTIMD 488
Query: 463 SWTRTPGIPIISVNTDTERTTLE--QHRFL 490
SWT G P++++ D T E Q R+L
Sbjct: 489 SWTLQTGFPVLNITRDYSTGTAEITQERYL 518
>7300768 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1878
Score = 144 bits (363), Expect = 6e-34
Identities = 148/589 (25%), Positives = 245/589 (41%), Gaps = 76/589 (12%)
Query: 10 VPLEYTLDL--NVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLI----------VT 57
+P Y + L NV F G + + L + K H +QL VT
Sbjct: 989 IPSHYAVSLSTNVHTGDTVFNGTVAITLSVLN---TTTKIVVHARQLENFTASIIQQGVT 1045
Query: 58 KVLLSDKPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFK 117
+ + + L Y+A + ++FS D T L I+Y G + T G F
Sbjct: 1046 EAVAQE--LVYEYEAEREFLTFSKTGLTFPEDTTWILTINYQGHLRT-------DNGGFY 1096
Query: 118 TNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVE 177
+ +D G + Y+ T + AR FPC+DEP+ + ++ +T+ D + ISN V+
Sbjct: 1097 LSTYTDEEG-NTKYLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNMPVD 1155
Query: 178 NRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHAT 237
+ S + + F KT M + F + + F ++ +P ++F+ H
Sbjct: 1156 SSSTSG----VTVFQKTVNMPSYLVAFIVSEFVFSEGEL----NGLPQRVFSRNGTEHEQ 1207
Query: 238 YSFDTIVELLPIVEKRLG----VDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTP 293
+ + +VEKRL V + L KLD +P + AMENWGL T++ +LL
Sbjct: 1208 ---EWALTTGMLVEKRLSGYFDVPFALPKLDQAGIPDFAAGAMENWGLATYREEYLLYNT 1264
Query: 294 QALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWF---ACDL-LDEHD 349
+ S S + + HE H W G+ ++ + W LW E FAT F A DL E D
Sbjct: 1265 EN-STTSTQTNIATIEAHEDAHMWFGDLVAIEWWSFLWLKEGFATLFENLAVDLAYPEWD 1323
Query: 350 NDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLR 409
+ + Y + + N S +A + + + S I + ++ Y K S+L
Sbjct: 1324 IFQTFHAGSYQSALVNDASANARPMSHFVQKPSEIAL--------LYDSVSYAKAGSVLD 1375
Query: 410 SLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSEN------IANFYSS 463
+ ++ F R L ++ T P +F + + EN + + S
Sbjct: 1376 MWRHALTNTVFQRGLHNYLVDNQF---TAANPSKLFEAIAKAAVEENYEVKATVPDMMGS 1432
Query: 464 WTRTPGIPIISV--NTDTERTTLEQHRFLLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLF 521
WT G+P+++V N D T++Q + +K D +++P+ +S D +N
Sbjct: 1433 WTNQGGVPLLTVTRNYDNGSFTVKQSVYTNDKDYTNDKLWYVPINYAESK-NPDFRNTEA 1491
Query: 522 TDRTLKLSEPE----------LIVNSGARGLYRVSYETDKCYELINEAL 560
T L SE LI+N + G YRV Y+ Y+LI AL
Sbjct: 1492 THYLLNQSEITIYSDLDQTNWLILNKKSTGYYRVLYDAQN-YQLITSAL 1539
Score = 129 bits (324), Expect = 2e-29
Identities = 118/485 (24%), Positives = 205/485 (41%), Gaps = 47/485 (9%)
Query: 102 VNTIKTHRELTTGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLT 161
+N HR G + +++ D ++ T + AR FPC+DEP + + +T
Sbjct: 158 INYTGIHRSDMGGFYISSYTDDDG--EQHFLATTQFESTNARHAFPCYDEPARRANFTIT 215
Query: 162 LTADDKFKVISNTSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNK 221
+ D + ISN V + + + F TP M+T F + D E ++ +
Sbjct: 216 IHHDPSYTAISNMPVNTAATSSG---VTAFQTTPKMSTYLVAFIVSDFESTTGELNGIRQ 272
Query: 222 TIPVQLFAPQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGL 281
+ + A +S +VE + GV + L KLD +P S AMENWGL
Sbjct: 273 RVFSRKGKQDQQEWALWS-GLLVE--SSLASYFGVPFALPKLDQAGIPDFSAGAMENWGL 329
Query: 282 LTFQMNHLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFA 341
T++ ++ Q S ++ + +I HE H W G+ +S W +LW E FAT F+
Sbjct: 330 ATYREQYMWWNKQN-STINLKTNIANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLFS 388
Query: 342 CDLLDEHDNDGYWSSDVY----LTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFE 397
E ++ + D Y + + + DA + +T V++ S+ +
Sbjct: 389 Y----ESNDIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTH----YVQTPSEISNRYN 440
Query: 398 PHIYHKGISLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGE------I 451
Y K S+L + + + F L + +++ T D+F E
Sbjct: 441 TFSYAKPASVLYMFKNAWTDKVFRTGLNKYLTKN---QYTSCDEWDLFASFQESADELGF 497
Query: 452 LKSENIANFYSSWTRTPGIPIISV--NTDTERTTLEQHRFLLEKTDVEDIPYHIPL-FAV 508
++ + +SSW+ G P+++V N + T+ Q R++ KTD +++PL FA
Sbjct: 498 TLPASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQKRYVANKTDTNSATWYVPLNFA- 556
Query: 509 QSSGEDDTKNGLFTDRTLKLSEPE-----------LIVNSGARGLYRVSYETDKCYELIN 557
++ + D ++ T L ++E +IVN G YR Y+T Y LI
Sbjct: 557 -TANKYDYRDTSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQN-YGLIT 614
Query: 558 EALKN 562
ALK+
Sbjct: 615 AALKS 619
>7300767 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 144 bits (362), Expect = 8e-34
Identities = 164/685 (23%), Positives = 280/685 (39%), Gaps = 86/685 (12%)
Query: 3 LSLTEPVVPLEYTLDLNVD-HK-QPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVL 60
L L PL Y L ++ D HK Q F G T+ + RQ S N+ H K L ++
Sbjct: 29 LRLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQ---STNEIVLHAKNLTDIQIT 85
Query: 61 LSDKPLSISYDANEQTVSFSSDDPLNIADDTAELRISY-IGKVNTIKTHRELTTGLFKTN 119
+ + + +E DD + TA L I + I + ++ + T
Sbjct: 86 VH----RLMAEGSEIV-----DDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLEILYTA 136
Query: 120 FMS------------DTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDK 167
M+ D Y+ AT +P + R IFPC+DEP K + + +T
Sbjct: 137 IMASRPAGLYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSS 196
Query: 168 FKVISNTSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQL 227
ISN V+ D K F TP ++T F I D + + ++I
Sbjct: 197 HSAISNMPVKEVLAHGDLKT-TSFHTTPPISTYLVAFVISDFGSISETYRGITQSIYT-- 253
Query: 228 FAPQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMN 287
+P S + V + +E GV YPL KLD V L AMENWGL+T++
Sbjct: 254 -SPTSKEKGQVALKNAVRTVAALEDYFGVSYPLPKLDHVALKKNYGAAMENWGLITYKDV 312
Query: 288 HLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFA---CDL 344
+LL + + + Q HE+ HQW GN +S + W + W NE FAT+F+ DL
Sbjct: 313 NLLKNISSDGQKRKLDLITQN--HEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDL 370
Query: 345 LDEHDNDGYWSSDVYLT-QMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHK 403
+ +D D+++T + ++ S ++ ++ V+ + F+ Y +
Sbjct: 371 IYPNDK----MMDMFMTHEADSAYSYNSFFDVHPMSH----YVEGEKDIMGVFDIISYKR 422
Query: 404 GISLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSE-------- 455
G +++ + ++ F R ++ + + + +++F + L+ +
Sbjct: 423 GACVIKMFHHAFRQKLFVRGISHFLEK---YRYSVANELNLFDALHSELQDDEYFSHQPW 479
Query: 456 --NIANFYSSWTRTPGIPIISVNTDTERTTLEQHRFLLEKTDVEDIPYHIPL-FA-VQSS 511
I SWT + +PI+ V + E T+ F ++D + IP+ FA QS
Sbjct: 480 ASRIREIMLSWTHSEWLPILVVTRNYENNTI---TFTQRSVHMKDELWWIPINFATTQSP 536
Query: 512 GEDDTKNGLF-----------TDRTLKLSEPE-LIVNSGARGLYRVSYETDKCYELINEA 559
+DT+ +F D + +S + ++VN G Y V Y+TD + +
Sbjct: 537 NFEDTQVDMFMPPQPQYTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYDTDNLMAIARQL 596
Query: 560 LKN-SKISDLDLFKIFIDLRSLIGSEYQKKIHIDGVLMILRCLASHVDLTEELYRGLSIG 618
N S I ++ +F DL LI E+ + ++ V +L+ L EL +
Sbjct: 597 QTNHSVIHPINRLGLFRDLGPLI--EHNEIEQVEVVFELLKYL--------ELEEDVLTW 646
Query: 619 LDILQTIENALRTYTGKSEKAFITD 643
+ TIE R G S ++ +
Sbjct: 647 NQLQDTIECLTRNLHGTSSQSLFNE 671
>CE18904 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 786
Score = 143 bits (360), Expect = 1e-33
Identities = 151/632 (23%), Positives = 266/632 (41%), Gaps = 60/632 (9%)
Query: 5 LTEPVVPLEYTLDLNV---------DHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLI 55
L V P EY L + D K F G + +Q++ ++ + H L
Sbjct: 32 LPRNVFPTEYRLHITTFLPGYKWEADEKSFTFIGDVKIQIEVKEETDTI---VLHTDSLN 88
Query: 56 VTKVLLSDKPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGL 115
+ VLL + + + Q + N + + S GK+ I+ E G
Sbjct: 89 INNVLLHNACVCANLKNLIQYFRLAITKFENRQQTNS--KYSLYGKIGKIREDGE---GY 143
Query: 116 FKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTS 175
++T +S + Y T +P AR + PCFDEP K + +T+ +SN
Sbjct: 144 YRT--ISPGLNETTMYNAVTQFEPTAARFMVPCFDEPEFKAIWHVTVVHPTGSTALSNAK 201
Query: 176 VENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA-PQSIS 234
+ + T+D +F T M++ +GD++F K + +++++ P I
Sbjct: 202 EIDNTKTNDDFSTTEFESTLKMSSYILAIFVGDVQFKEAVTK---NGVRIRVYSDPGHID 258
Query: 235 HATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQ 294
++ + +L EK+ G Y ++KLD++ + AMENWGL+ Q L+
Sbjct: 259 SVDHALNVSRIVLEGFEKQFGYPYEMDKLDLIAVYNFRYGAMENWGLIVHQAYTLIENLM 318
Query: 295 ALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATW---FACDLLD-EHDN 350
P + +++ HE+ HQW GN ++ WD LW NE FAT+ + LD +D
Sbjct: 319 ----PGNTDIISEVVAHEIAHQWFGNLVTMKFWDQLWLNEGFATYMTAYGYTFLDPNYDR 374
Query: 351 DGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRS 410
D Y+ S + +Q N + G + + L + Y KG S +R
Sbjct: 375 DYYYLSPQFESQSGNEL-------------GPLNSMIKLSHGAIGNPSQNYAKGCSFIRM 421
Query: 411 LQQSVGKENFNRALAQIFSESSTFHETCIKPM-DIFRRMGEIL----KSENIANFYSSWT 465
L++ VG E+FN A+ + + + F K + D R + L K +I F WT
Sbjct: 422 LEKIVGTEHFNEAI-RTYLHTHDFSNVEDKNLYDALRVYSDKLEINGKPFDIEEFGRCWT 480
Query: 466 RTPGIPIISVNT----DTERTTLEQHRFLLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLF 521
G P + V++ T + ++ + + + IP++ QS + L
Sbjct: 481 HQTGYPTVYVSSYYAGQTRLSQVKVKEIVTGDFHECNNKWDIPIWYQQSGSTEVELTWLE 540
Query: 522 TDR-TLKLSEPEL-IVNSGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFIDLRS 579
D+ L+++ I+N+ + GLY V Y ++ YE + LKN+ K + L
Sbjct: 541 KDQDELEINTTGFAIINANSNGLYDVVY-SEVLYEQVASELKNNTQMYSASTKARV-LSD 598
Query: 580 LIGSEYQKKIHIDGVLMILRCLASHVDLTEEL 611
I Y+ ++ + L+I + LA+ D +E+
Sbjct: 599 AIHYYYKGEVSLKNSLIIAQALAN--DTNQEI 628
>CE20255 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1045
Score = 142 bits (359), Expect = 2e-33
Identities = 110/412 (26%), Positives = 187/412 (44%), Gaps = 32/412 (7%)
Query: 111 LTTGLFKTNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKV 170
L GLF + + Y++AT Q AR++FPC D P+ K ++ +
Sbjct: 265 LAYGLFAAPYTFEN---ETRYVVATQLQISEARTVFPCIDVPDMKAQFDTVIIHPTGTTS 321
Query: 171 ISNTSVENRSVTDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFA- 229
I+N +EN + D F +TP M+T F F + D +L T + + +++
Sbjct: 322 IANM-MENSTKVDGEWTTTTFHRTPPMSTYLFAFSVSDYPYLET---FSGRGVRSRVYCD 377
Query: 230 PQSISHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHL 289
P + A +I +L E G+ YPLEKLDVV++P LS AMENWGL+T + +
Sbjct: 378 PTKLVDAQLITKSIGPVLDFYEDYFGIPYPLEKLDVVIVPALSVTAMENWGLITIRQTNG 437
Query: 290 LLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHD 349
L T + S V++++ HEL HQW GN ++ W+ LW NE FAT + +D +
Sbjct: 438 LYTEGRFA-ISQKHDVQEIVAHELAHQWFGNLVTMKWWNDLWLNEGFATLISVRAVDFLE 496
Query: 350 N------DGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHK 403
N D S + + + S K+ S ++++ + IY K
Sbjct: 497 NTTWRYEDSSAESQCVALRADQIDSISPVSGKKNSNFDSYMEIQG--------KAIIYKK 548
Query: 404 GISLLRSLQQSVGKENFNRALAQI---FSESSTFHETCIKPMDIFR--RMGEILKSEN-- 456
++R +++ V ++ F + L + F + HE + G L+ +N
Sbjct: 549 SAIIIRMIERLVEEDIFRQGLKRFLNTFLYKNADHEDLFNVLVYVHDSSAGGHLRGQNFS 608
Query: 457 IANFYSSWTRTPGIPIISVN-TDTERTTLEQHRF-LLEKTDVEDIPYHIPLF 506
+++ +W R P+I VN + TL Q ++ + + + E + IP+F
Sbjct: 609 LSDVMDTWIRQAHFPVIHVNRKEGSLVTLRQEKYEHVPRDEPEKQVWKIPIF 660
>Hs22064092 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 478
Score = 141 bits (356), Expect = 4e-33
Identities = 111/433 (25%), Positives = 198/433 (45%), Gaps = 38/433 (8%)
Query: 5 LTEPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQL-IVTKVLLSD 63
L V P+ +L L D F+G+L + RQ + N+ +C + I+T +
Sbjct: 54 LPADVSPINCSLCLKPDLLDFTFEGKLEAAAQVRQ---ATNQIVMNCADIDIITASYAPE 110
Query: 64 KPLSI-----SYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKT 118
I +Y ++ V+ S P + T L+I ++G++N + G +++
Sbjct: 111 GDEEIHATGFNYQNEDEKVTLSF--PSTLQTGTGTLKIDFVGELN------DKMKGFYRS 162
Query: 119 NFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVEN 178
+ + + + Y T + AR FPC+DE K + ++L +SN +V +
Sbjct: 163 KYTTPSGEVR--YAAVTQFEATDARRAFPCWDERAIKATFDISLVVPKDRVALSNMNVID 220
Query: 179 RSVTDDRKQIV--KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQS-ISH 235
R D + +V KF++TP+ +T F +G+ +F+ T K + V ++ P
Sbjct: 221 RKPYPDDENLVEVKFARTPVTSTYLVAFVVGEYDFVETRSK---DGVCVCVYTPVGKAEQ 277
Query: 236 ATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQA 295
++ + + LP + V YPL K+D++ + + AMENW L+T++ LL+ P+
Sbjct: 278 GKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWDLVTYRETALLIDPKN 337
Query: 296 LSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLD----EHDND 351
S S Q V ++ HEL HQW GN ++ + W HL NE FA+W +D E+D
Sbjct: 338 -SCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLRLNEGFASWIEYLCVDHCFPEYDIW 396
Query: 352 GYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSL 411
+ S Y E ++ S+ S +D + F+ Y KG S++R L
Sbjct: 397 TQFVSADYTRAQELDALDNSHPIEVSVGHPSEVD--------EIFDAISYSKGASVIRML 448
Query: 412 QQSVGKENFNRAL 424
+G ++F + +
Sbjct: 449 HDYIGDKDFKKGM 461
>7301770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 814
Score = 141 bits (355), Expect = 5e-33
Identities = 110/429 (25%), Positives = 196/429 (45%), Gaps = 40/429 (9%)
Query: 26 NFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDKPLSISYDANEQT----VSFSS 81
+F G + +Q++ Q + + H K L + D +++S E+T ++ ++
Sbjct: 51 HFNGTVKIQIEVLQ---NTHNITLHSKDLTI-----DDTEITLSQIGGEETTENCITSTA 102
Query: 82 DDPLN-----------IADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDTTGISDS 130
+P + +A EL + + K+ ++ G +++++++ T
Sbjct: 103 VNPTHDFYILNTCKELLAGQFYELSLPFSAKL------QDQLAGYYRSSYVN-TVANETR 155
Query: 131 YILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIV- 189
+I T +P AR FPCFDEP K + +TL K+ +SN V + V
Sbjct: 156 WISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRPHESIPDYVW 215
Query: 190 -KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLP 248
F ++ M+T + + D F L N T+ P +I Y+ + ++L
Sbjct: 216 TSFEESLPMSTYLVAYSLND--FSHKPSTLPNGTLFRTWARPNAIDQCDYAAELGPKVLK 273
Query: 249 IVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQL 308
E+ G+ +PL K+D + +P S AMENWGL+TF + LL +P+ S Q+ +
Sbjct: 274 YYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSPE-YSSQEAKQETANI 332
Query: 309 IVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIS 368
+ HEL HQW GN ++ W LW NE FAT+ A L D W + + L M N+++
Sbjct: 333 VAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAS--LCVEDIHPQWRT-LQLESMSNLLT 389
Query: 369 TDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIF 428
+ + +S + ++ S++F+ Y KG S++R + +G+E F L +
Sbjct: 390 IFRKDSLES-SHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKLVL 448
Query: 429 -SESSTFHE 436
S T H+
Sbjct: 449 ESVPKTIHD 457
>7301751 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1017
Score = 137 bits (344), Expect = 1e-31
Identities = 119/461 (25%), Positives = 200/461 (42%), Gaps = 38/461 (8%)
Query: 131 YILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSV--ENRSVTDDRKQI 188
++ +T Q AR FPCFDEP K + L + ISN + N T
Sbjct: 260 WVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVW 319
Query: 189 VKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLP 248
F+++ M+T + I D T + N + + A I A Y+ +L
Sbjct: 320 DHFAESLPMSTYLVAYAISDF----THISSGNFAVWARADA---IKSAEYALSVGPRILT 372
Query: 249 IVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQL 308
++ V +PL K+D++ LP AMENWGL+TF+ +L P ++ + Q+V +
Sbjct: 373 FLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDP-GVATANNKQRVASV 431
Query: 309 IVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIS 368
+ HEL HQW GN ++ W +W NE FA++ D + + +++ V
Sbjct: 432 VGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQ 491
Query: 369 TDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIF 428
DA T+ I+ +V + Q S+ F+ Y KG +++R + + F R L++
Sbjct: 492 LDALSTSHKISH----EVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYL 547
Query: 429 SE---SSTFHETCIKPMDIFRRMGEIL-KSENIANFYSSWTRTPGIPIISV----NTDTE 480
E +S + + + + +L S ++ +WT G P++ V N+D
Sbjct: 548 QEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVI 607
Query: 481 RTTLEQHRFLLEKTDVED--IPYHIPLFAVQSSGED--DTKNGLFTDRTLKLSEPE---- 532
R LEQ RF+ T ED + ++IP+ S + +T+ + RT KL E E
Sbjct: 608 R--LEQVRFVYTNTTREDESLLWYIPITFTTDSELNFANTRPTTWMPRT-KLYELENREL 664
Query: 533 -----LIVNSGARGLYRVSYETDKCYELINEALKNSKISDL 568
I N G YRV+Y+ + + + D+
Sbjct: 665 SLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDI 705
>CE26001 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1815
Score = 130 bits (328), Expect = 7e-30
Identities = 121/522 (23%), Positives = 221/522 (42%), Gaps = 51/522 (9%)
Query: 23 KQPNFKGQLTVQLKQRQPGQSF--NKFKFHCKQLIVTKVLLSDKPL-SISYDANEQTVSF 79
K F G+ ++Q++ F N + F + V + + P+ SIS D Q +S
Sbjct: 109 KNFTFDGRASIQVEALVASDRFILNAYNFKIQSYKVVDIDGTVVPINSISQDDTTQQLSL 168
Query: 80 SSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDTTGISDSYILATHTQP 139
++ +A + Y G +N G++ T++ +D G + Y++ATH +P
Sbjct: 169 ITNANGVVAGQIYNIEFVYTGIINPYTDG-----GVYYTSY-NDPQG-NTHYMIATHMEP 221
Query: 140 VFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKTPLMNT 199
AR +FP DEP+ K K+ +T+ +SN + D+ + F +TP M++
Sbjct: 222 FSARKVFPSLDEPSYKAKFTITVQYPASQVALSNMMETEPTKIDNIWSTITFPQTPKMSS 281
Query: 200 SYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKRLGVDYP 259
F +G ++ + K+ T+ P + + ++ E L + + G+ +P
Sbjct: 282 YLIAFAVG--PYVNSQYVNKHNTLTRAWGWPGTEQYLQFAAQNAGECLYQLGEYTGIKFP 339
Query: 260 LEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIVHELCHQWMG 319
L K D + +P AMENWGL+ ++ ++ P ++ + ++ +++ HEL HQW G
Sbjct: 340 LSKADQLGMPEFLAGAMENWGLIIYKYQYIAYNPTTMTTRN-MEAAAKVMCHELAHQWFG 398
Query: 320 NYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVISTDAEVTTKSIT 379
+ ++ WD L+ NE FA +F + VY Q + D +
Sbjct: 399 DLVTTAWWDDLFLNEGFADYFMT----------FIQKSVYPQQATYL---DTLQVLDELQ 445
Query: 380 QGSVIDVK-----SLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIFSESSTF 434
G DV+ + AF+ Y+KG S+LR L +G + F + + +
Sbjct: 446 VGLTADVRYDAHPLVYPDGPAFDDITYNKGASMLRMLSDVLGADVFKQGIRAYLQK---M 502
Query: 435 HETCIKPMDIFRRMGEILKSENI----------ANFYSSWTRTPGIPIISVNTDTE--RT 482
+ D+F + + KS NI +F + P+I N + + +
Sbjct: 503 QYSNANDFDLFSTLTDTAKSNNILDWCGLPLNVTDFMQPYIHQTNHPLIRYNNNQKIGGS 562
Query: 483 TLEQHRFLLEKTDVEDIPYH----IPLFAVQSSGEDDTKNGL 520
T Q F L+ +D+ P++ IPL + D K L
Sbjct: 563 TFSQEPF-LDISDLTATPWNYTWSIPLTSANLRHADPYKQWL 603
Score = 105 bits (261), Expect = 4e-22
Identities = 99/439 (22%), Positives = 181/439 (40%), Gaps = 36/439 (8%)
Query: 142 ARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKTPLMNTSY 201
ARS+ PC+DEP+ K ++++++ +SN R++ D+ KF+ T M+T
Sbjct: 1148 ARSLLPCWDEPSYKGQFEVSVFHPTDMIALSNEVDIQRTIYDNGWTTTKFATTNQMSTYL 1207
Query: 202 FGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKRLGVDYPLE 261
C+G L T V V ++ + ++ + + +E D+PL+
Sbjct: 1208 LALCVGHFSNLAT-VTRTGVLTRVWTWSGME-QYGEFALNVTAGTIDFMENYFSYDFPLK 1265
Query: 262 KLDVVLLP--FLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIVHELCHQWMG 319
KLDV+ LP ++ AMENWGL+ + + + P + I +V + HE+ HQW G
Sbjct: 1266 KLDVMALPEYTMNAGAMENWGLIIGEYSLFMFDPDYATTRD-ITEVAETTAHEVVHQWFG 1324
Query: 320 NYISFDSWDHLWFNEAFAT-WFACDLLDEHDNDGYWSSDVYLTQMENVISTDAEVTTKSI 378
+ ++ D W+ ++ NE FA WFA + + +S D M ++
Sbjct: 1325 DIVTLDWWNDIFLNEGFAQYWFANGIDNTFPEQHAYSIDYNRFYMNHI------ALKYDC 1378
Query: 379 TQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIFSESSTFHETC 438
G V + T F Y+KG +LL L + F L+ ++ + +
Sbjct: 1379 IPGVAKPV--ISDTPPVFGIEPYYKGSALLNLLNNVLTPAVFQEGLSSYLTQYGYVNAS- 1435
Query: 439 IKPMDIFRRMGEILKSENI----------ANFYSSWTRTPGIPIISVNTDTERTTLEQHR 488
P +++ + + NI ++F +T PII++ T +
Sbjct: 1436 --PRNLWTSLTVAAQRHNITDWNGQPLDVSSFMDPYTLQTSYPIITLTLRGTSTVQANQQ 1493
Query: 489 FLLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLFT---DRTLKLSEPE--LIVNSGARGLY 543
+ ++ +++PLF D FT D T P + N+G+
Sbjct: 1494 SCMS----DETLWNVPLFTQTPGALDFNWFVNFTGGNDATWLRPLPTGYRVDNAGSTSFA 1549
Query: 544 RVSYETDKCYELINEALKN 562
R++Y+ Y + + L N
Sbjct: 1550 RINYDDKSWYSIQAQLLSN 1568
>CE27507 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1073
Score = 128 bits (321), Expect = 4e-29
Identities = 99/378 (26%), Positives = 173/378 (45%), Gaps = 41/378 (10%)
Query: 135 THTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNT----SVENRSVTDDRKQIVK 190
T +P AR+ FPC+DEP K + +++ + K+ V+SN S +++S D K V
Sbjct: 240 TKFEPTLARAFFPCWDEPGVKATFNISVRHNKKYTVLSNMPPVESHDHKSWEDQFKTTV- 298
Query: 191 FSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKT---IPVQLFA-PQSISHATYSFDTIVEL 246
F TP M+T F IG+ VKL+++T IPV ++ P+ + ++ + +
Sbjct: 299 FQTTPPMSTYLLAFAIGEF------VKLESRTERGIPVTVWTYPEDVMSMKFTLEYAPVI 352
Query: 247 LPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQ--- 303
+E L + YPL K+D++ MENWGL+ F+ + TP +
Sbjct: 353 FDRLEDALEIPYPLPKVDLIAARNFHVGGMENWGLVVFEFASIAYTPPITDHVNETVDRM 412
Query: 304 ----QVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVY 359
++ +LI HE HQW GN ++ W L+ NE FAT++ +++ +
Sbjct: 413 YNEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFATFYVYEMMS--------TERPV 464
Query: 360 LTQMENVISTDAEVTTKSITQGSVIDVKSLQSTS---DAFEP-HIYHKGISLLRSLQQSV 415
Q E S + + +S + V+ L + S +F P ++Y KG L+R L+ V
Sbjct: 465 TAQFEYYDSLASLILAQSEEDHRLSLVRELATESQVESSFHPTNLYTKGCVLIRMLRDLV 524
Query: 416 GKENFNRALAQIFSES---STFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPI 472
+F A+ + ++ S + + + G + E +++ W GIP
Sbjct: 525 SDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHG--AEQEKLSHVLEGWFVNEGIPE 582
Query: 473 ISV--NTDTERTTLEQHR 488
I++ N D E T+ Q +
Sbjct: 583 ITLIRNYDNEMMTISQRK 600
>7291179 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 931
Score = 124 bits (311), Expect = 6e-28
Identities = 132/511 (25%), Positives = 214/511 (41%), Gaps = 53/511 (10%)
Query: 9 VVPLEYTLDLNVDHKQPN--FKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTK---VLLSD 63
+VPL Y +D+ QP F G + + L+ + S + + L + K V LSD
Sbjct: 30 LVPLSYRVDIVTRINQPYQPFGGTVVIDLRSER---STKRIVLNAHDLAIGKRRAVTLSD 86
Query: 64 K-----PLS-ISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFK 117
K P+S I D ++ S PL + ++Y +V R TG +
Sbjct: 87 KNGNSVPVSSIQMDIKLSRLTVSLKRPLKV-------NVTYSMRVAFTSVLRNDNTGFYS 139
Query: 118 TNFMSDTTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVE 177
+N++ T ++ ++ AT +P AR FPCFD+P + +++ L ++ +SN V+
Sbjct: 140 SNYVDHNTTLTQ-WLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQ 198
Query: 178 NRSVTDDRKQIV--KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKT-IPVQLFA-PQSI 233
K V +F ++ M T F I +F R ++ P+ +A P ++
Sbjct: 199 RTIRHASLKDYVWTQFVESHPMQTYLVAFMIS--KFDRPGFTSSERSDCPISTWARPDAL 256
Query: 234 SHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTP 293
S ++ + LL E Y +K+D+V LP + + ENWGL F LL
Sbjct: 257 SQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDS 316
Query: 294 QALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFA----CDLLDEHD 349
Q S Q V + + + +QW GN +S W +W FA + + L E D
Sbjct: 317 QRSSIDDQ-QGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWD 375
Query: 350 NDGYWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLR 409
+ +YL +V+ DA V T +T SV D + + A+ K L
Sbjct: 376 YQERHALQLYL----SVLDYDAHVNTDLVT-ASVPDESHIWA---AYNEIGERKAAVLFE 427
Query: 410 SLQQSVGKENFNRAL-------AQIFSESSTFHETCIKPMDIFRRMGEILKSENIANFYS 462
L + +G+E + AL A + SS F + +D R G + K NI
Sbjct: 428 MLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVD---RNGRLGKGLNITRIMK 484
Query: 463 SWTRTPGIPIISV--NTDTERTTLEQHRFLL 491
W PG P+++V N D + Q RF +
Sbjct: 485 CWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI 515
>7291558 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 844
Score = 120 bits (301), Expect = 9e-27
Identities = 117/481 (24%), Positives = 202/481 (41%), Gaps = 42/481 (8%)
Query: 198 NTSYFGFCIGDLEFLRTDV-KLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKRLGV 256
+T F + DLE T+ K N+ I P+ + S + +LL E +
Sbjct: 155 STYLVAFAVHDLENAATEESKTSNRVIFRNWMQPKLLGQEMISMEIAPKLLSFYENLFQI 214
Query: 257 DYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQ--VRQLIVHELC 314
++PL K+D + +P AMENWGL+T+ L PQ D Q+ + HE
Sbjct: 215 NFPLAKVDQLTVPTHRFTAMENWGLVTYNEERL---PQNQGDYPQKQKDSTAFTVAHEYA 271
Query: 315 HQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVISTDAEVT 374
HQW GN ++ + W+ LW E +T+F LD + + N S D+ T
Sbjct: 272 HQWFGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERFISRDLANFFSKDSNAT 331
Query: 375 TKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENF---NRALAQIFSES 431
+I++ DVK+ F ++Y KG +R L + VG+E F R+ + FS
Sbjct: 332 VPAISK----DVKNPAEVLGQFTEYVYEKGSLTIRMLHKLVGEEAFFHGIRSFLERFSFG 387
Query: 432 STFHETCIKPMDIFRRMGEILKSE-NIANFYSSWTRTPGIPIISV--NTDTERTTLEQHR 488
+ + + +++ S+ N++ SWT G P++++ N T TL Q R
Sbjct: 388 NVAQADLWNSLQMAALKNQVISSDFNLSRAMDSWTLQGGYPLVTLIRNYKTGEVTLNQSR 447
Query: 489 FLLEK-TDVEDIPYHIPLFAVQSSGEDDTKNG-------LFTDRTLKL-----SEPELIV 535
F E + + +PL V+ + D + + LKL ++ +I+
Sbjct: 448 FFQEHGIEKASSCWWVPLRFVRQNLPDFNQTTPQFWLECPLNTKVLKLPDHLSTDEWVIL 507
Query: 536 NSGARGLYRVSYETDKCYELINEALKNSK----ISDLDLFKIFIDLRSLIGSEYQKKIHI 591
N ++RV+Y+ + + LI E+L+N I L+ ++ DL +L K
Sbjct: 508 NPQVATIFRVNYD-EHNWRLIIESLRNDPNSGGIHKLNKAQLLDDLMALAAVRLHK---Y 563
Query: 592 DGVLMILRCLASHVDLTEELYRGLSIGLDILQTIENALRTYTGKSEKAFITDIYVPLWDK 651
D +L L D + + IL + L K ++ + +PL+++
Sbjct: 564 DKAFDLLEYLKKEQD-----FLPWQRAIGILNRLGALLNVAEANKFKNYMQKLLLPLYNR 618
Query: 652 F 652
F
Sbjct: 619 F 619
>CE05135 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1071
Score = 103 bits (257), Expect = 1e-21
Identities = 117/543 (21%), Positives = 224/543 (40%), Gaps = 73/543 (13%)
Query: 64 KPLSISYDANEQTVSFSSDDPLNIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSD 123
K +I +D N + V+ + D L T L+I + KV+ GL + + +
Sbjct: 268 KVTNIEFDENLEKVTLTLDQELK-KGSTVVLKIPFTSKVSN-------NNGLKEYKYKNS 319
Query: 124 TTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTD 183
+ + T + R +FP FD+ K +TL V++NT V+ + D
Sbjct: 320 EG--KEQSMFTTQPSYSYLRHVFPSFDQEAFKAPAAITLMHSKGSIVVANTGVKTKDDGD 377
Query: 184 DRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHAT-YSFDT 242
+ + P F IGDL + I ++++ + H+T S D
Sbjct: 378 AQTSTLNKVLDP-------DFVIGDLVASEVNT---TSGITIRIWTRPEVKHSTEQSLDY 427
Query: 243 IVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVI 302
+ + +E L + LD+V +P + + +L Q+ +D +
Sbjct: 428 ANQAIDAMEHILQSRLESKSLDIVAVPGFQTGNRVSPSFIVLPEEDILYNEQS-NDINQK 486
Query: 303 QQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQ 362
++ ++I + + QW G + + + W NEA + + L++ + S D++ +
Sbjct: 487 TRIARMISNRIAAQWFGGITNPEEFGTFWLNEALPRFLEVEALEKILDIN--SDDLWTYE 544
Query: 363 MENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFE---PHIYHKGISLLRSLQQSVGKEN 419
ME ++ DA T++ + VK++ S++D E I KG ++LR +Q+SVG
Sbjct: 545 MEKILERDATATSQPLR------VKNVFSSADIAEIDHEFIGKKGAAVLRMIQKSVGVNV 598
Query: 420 FNRALAQIFS---ESSTFHETCIKPMDIFRRMGEILKSEN-----IANFYSSWTRTPGIP 471
FN+A+ S + + + K + + +G LK N +A F ++W G P
Sbjct: 599 FNKAIRSFVSSYRSAYPYDDGLWKSFE--KALGGKLKGWNNEPLDVAKFVNTWVDQIGFP 656
Query: 472 IISV-NTDTERTTLEQHRFLLEKTDVEDIPY---------HIPLFAVQSSGEDDTKNGLF 521
++SV D E L Q RF + E + +PL + +S
Sbjct: 657 LVSVEKLDDETVELSQERFKNDHKTKEQFKFRNAKYWFNWEVPLLPLNTS---------- 706
Query: 522 TDRTLKLSEPELIVNSGARGLYRVSYETDKCYELINEALK-NSKISDLDLFKIFIDLRSL 580
+ +N+ + G+YRV+YE + ++ + K + K+S+ ++ D+ +L
Sbjct: 707 ---------DSIYLNTDSNGVYRVNYEEKRWNDIAKQLEKSHGKLSERTRARLISDVFAL 757
Query: 581 IGS 583
S
Sbjct: 758 ANS 760
>At4g33090 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 873
Score = 102 bits (253), Expect = 3e-21
Identities = 161/730 (22%), Positives = 279/730 (38%), Gaps = 130/730 (17%)
Query: 135 THTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKT 194
T +P AR FPC+DEP K +++TL +SN + V + K IV + ++
Sbjct: 150 TQFEPADARRCFPCWDEPACKATFKITLEVPTDLVALSNMPIMEEKVNGNLK-IVSYQES 208
Query: 195 PLMNTSYFGFCIGDLEFLRTDVK----LKNKTIPVQLFAPQSISHATYSFDTIVELLPIV 250
P+M+T +G +++ L +T+ +F ++ I+ L
Sbjct: 209 PIMSTYLVAIVVGLFDYVEDHTSDGPSLTFETLCACIFL-------SFFNGCIISLHKSN 261
Query: 251 E--KRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQL 308
+ V YPL K+D++ +P + AMEN+GL+T++ LL Q S S Q+V L
Sbjct: 262 HSCRYFAVPYPLPKMDMIAIPDFAAGAMENYGLVTYRETALLYDEQH-SAASNKQRVSYL 320
Query: 309 IVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIS 368
L +W +W LDE + + L +E
Sbjct: 321 ATDSLFPEWK-----------IW----------TQFLDES------TEGLRLDGLEESHP 353
Query: 369 TDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIF 428
+ EV + ID + F+ Y KG S++R LQ +G E F ++LA
Sbjct: 354 IEVEVN-----HAAEID--------EIFDAISYRKGASVIRMLQSYLGAEVFQKSLAAYI 400
Query: 429 SESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTERTTLEQHR 488
+ + K D++ + E E + SSWT+ G P++S + LEQ R
Sbjct: 401 KNHAYSNA---KTEDLWAAL-EAGSGEPVNKLMSSWTKQKGYPVVSAKIKDGKLELEQSR 456
Query: 489 FLLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLSEPELI-------------- 534
FL + E + +P+ S E KN L ++ EL+
Sbjct: 457 FLSSGSPGEG-QWIVPVTLCCGSYE-KRKNFLLESKSGAYDLKELLGCSIADGSDKINGT 514
Query: 535 -----VNSGARGLYRVSYETDKCYELINEALKNSKISDLDLFKIFIDLRSLIGSEYQKKI 589
+N G YRV Y+ D + A ++ ++ +D + I D +L + Q
Sbjct: 515 CSWIKINVDQAGFYRVKYD-DSLAAGLRNATESQSLTSIDRYGILDDSFALTMARQQS-- 571
Query: 590 HIDGVLMILRCLASHVDLT------EELYRGLSIGLDILQTIENALRTYTGKSEKAFITD 643
+ +L + +D T Y+ + IG D Q + + + K F
Sbjct: 572 -LASLLTLCSAYKKELDYTVLSNLIAISYKVVKIGADANQELMSGI--------KHFFIG 622
Query: 644 IYVPLWDKFSWNDFHVSSY---QLKVMSKVMFGIKHLDSTLTVANQLMKKILSGPNKS-I 699
++ K W+ S+ L+ + D TL A + L+ N +
Sbjct: 623 VFQFAAGKLGWDPKQGESHLDAMLRGEVLTALAVFGHDETLKEAVRRFDAFLADRNTPLL 682
Query: 700 PLELCGSVFATVSCHQKNVKQWKKLYELVKSAKGVESHVDGGSSIDIQNMALENLAFNTN 759
P ++ + + V Q+ K K YE S V D + L +LA +
Sbjct: 683 PPDIRRAAYVAVM--QRANKSDKSGYE---SLLRVYRETDLSQE---KTRILGSLASCPD 734
Query: 760 EELIKKTLNFILT-----------NITSTSVENALFGLNYNFREPLDGKKNKLVRDVCWE 808
+++ LNF+L+ ++ ++AL+GL+ E R+V W+
Sbjct: 735 PTIVQDVLNFVLSDEVDYMDFAFHSVELVRNQDALYGLSGVSWEG---------REVAWK 785
Query: 809 WFELNYDLWG 818
W + ++ G
Sbjct: 786 WLQEKWEYIG 795
>CE13593 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 556
Score = 100 bits (250), Expect = 8e-21
Identities = 94/422 (22%), Positives = 174/422 (40%), Gaps = 41/422 (9%)
Query: 132 ILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKF 191
+ TH QP AR +FPC D P K ++L++ SNT + V + + Q F
Sbjct: 48 LYTTHLQPNHARRLFPCIDHPAVKALFRLSIVHPTDTVAQSNTIAMDVHVENRKWQRTIF 107
Query: 192 SKTPLMNTSYFGFCIGDLEFLRTDVKLKNKT---IPVQLFAPQSISHATYSFDTIVELLP 248
TPL+ F + ++++L +T + V++ +S D +
Sbjct: 108 QATPLLPAYLVAFSV----MPDSNLQLSRQTSFGVTVRVNG-ESRGLVLRVLDCALASFE 162
Query: 249 IVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQL 308
I+ + V PL K+D +L+P D MENWG +T + L+ + L
Sbjct: 163 ILAGLIDVPLPLNKIDFILVPEY-DGGMENWGHIT--------VSETLATSGDDAHLIYL 213
Query: 309 IVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIS 368
I HE+ H W+GN + DSW+ + E W A + + ++ L + +
Sbjct: 214 IAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAV-----KALLTDEIRLQRFQLAQY 268
Query: 369 TDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIF 428
+ ++ ++ G + + S + + H Y KG+ LL +L+ VG++ + +
Sbjct: 269 VEIQLVEDFLSPGHSLYMPS-KINQELINRHCYLKGVVLLDTLESVVGEQFMYSVIKSLV 327
Query: 429 SESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDTERTTLEQHR 488
ST++ T F ++ + ++ + Y W T G P I V + + L+Q
Sbjct: 328 GSHSTYNLTTF--TSYFDQI-RVDRNATVGQIYEYWYTTGGYPSILVENNGPSSRLQQ-- 382
Query: 489 FLLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLFTDRTLKLSE-PELIVNSGARGLYRVSY 547
PL+ ++ + +F++ + SE L+VN RV+Y
Sbjct: 383 ------------LSRPLWPLKMTSTLAIPQFVFSESIVFASENAPLLVNLNFTSFMRVNY 430
Query: 548 ET 549
++
Sbjct: 431 DS 432
>7298258 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 578
Score = 97.8 bits (242), Expect = 6e-20
Identities = 104/448 (23%), Positives = 188/448 (41%), Gaps = 38/448 (8%)
Query: 135 THTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVE----NRSVTDDRKQIVK 190
+H + R+ P FDEP+ K + +T+ +F+ N V+ NR + D + +
Sbjct: 42 SHFNRNWIRNTMPSFDEPSLKATFNVTMGHHKRFQSYGNMKVQAVLPNREIQDYVWSVHE 101
Query: 191 FSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHAT-YSFDTIVELLPI 249
TP + T F + + R + + A + AT ++ ++L
Sbjct: 102 V--TPTIPTHLLAFSVNNFN-CRYSQAASLSPVRFRTCAQSADVRATSFAAQMAPQILEF 158
Query: 250 VEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLI 309
+++ L V PLEK+D +++ AMEN+GL+ ++ HLLL +Q + +LI
Sbjct: 159 LDRVLQVALPLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTL-ELI 217
Query: 310 VHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIST 369
HE+ H W N + DS+ LW E A +F +D + + L E+ +
Sbjct: 218 AHEMAHMWFDNLLGMDSYSDLWLTEGLAGYFKSLAVDHLQSK--MGRRILLRYRESSMMY 275
Query: 370 DAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIFS 429
+++V G + V + S E +Y K SL L +G E F L +
Sbjct: 276 ESQV-------GGISLVPLSSNASLNAETQLYQKATSLTSMLIGFLGNETFYDGLQRHMW 328
Query: 430 ESSTFHETCIKPMDIFRRMGEIL--------KSENIANFYSSWTRTPGIPIISVNTDTER 481
++S T D+F R ++ K+ ++ + +WT G P+++V +
Sbjct: 329 QNSFGSST----PDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQSGYPLVTVIRNGSE 384
Query: 482 TTLEQ-HRFLLEKTDVEDIPYHIPLFAVQSSGEDDTKNGLF-TDRTLKLSE-----PELI 534
L+Q H + + IP + S K L +KL++ ++
Sbjct: 385 VFLKQGHALNRSSSHLWWIPLTYLIEGGSLSKNLKPKAWLSPNSHGIKLNDIVPRNQWIL 444
Query: 535 VNSGARGLYRVSYETDKCYELINEALKN 562
+N A G YRV+Y+ + ++L+ L N
Sbjct: 445 LNLQAVGYYRVNYD-ELTWQLLATTLFN 471
>CE24840 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 609
Score = 77.4 bits (189), Expect = 9e-14
Identities = 96/424 (22%), Positives = 171/424 (39%), Gaps = 51/424 (12%)
Query: 7 EPVVPLEYTLDLNVDHKQPNFKGQLTVQLKQRQPGQSFNKFKFHCKQLIVTKVLLSDKPL 66
E V Y L VD ++ + G +++ L +Q + ++++ LS + +
Sbjct: 16 EQVTVSHYALKWKVDFEKKHIAGDVSITLDVKQDTE----------RIVLDTRDLSVQSV 65
Query: 67 SISYDANEQTVSFSSDDPLNIADD---TAELRISYIGKVNTIKTHRELTTGLFKTNFMSD 123
+++ + + F+ +D + T E S V IK +
Sbjct: 66 ALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQ 125
Query: 124 TTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTD 183
TT Y+ + Q + ARSI PC D P+ K Y+ + + + + + ++
Sbjct: 126 TTDRVAPYLFS-QCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSE 184
Query: 184 DRKQIVKFSKTPLMNTSYF-GFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHAT-YSFD 241
K+ + K P+ SY +G LE R ++ + ++A S + A+ Y F
Sbjct: 185 CGKRTIFSFKQPVSIPSYLLAIVVGHLE--RKEISER-----CAVWAEPSQAEASFYEFA 237
Query: 242 TIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMA-MENWGLLTFQMNHLLLTPQALS-DP 299
++L + E G Y + D+V+LP MEN LTF +TP L+ D
Sbjct: 238 ETEKILKVAEDVAG-PYVWGRYDLVVLPATFPFGGMEN-PCLTF------ITPTLLAGDR 289
Query: 300 SVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDL-------LDEHDNDG 352
S++ +I HE+ H W GN ++ SW+H W NE F + + L+
Sbjct: 290 SLVN----VIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMYGELERQFESE 345
Query: 353 YWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQ 412
+ + + +V D E T G+ DAF Y KG +LL +++
Sbjct: 346 SGYEEALVRTVNDVFGPDHEYTKLVQNLGNA-------DPDDAFSSVPYEKGSALLFTIE 398
Query: 413 QSVG 416
Q++G
Sbjct: 399 QALG 402
>7291178 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 911
Score = 75.9 bits (185), Expect = 3e-13
Identities = 103/484 (21%), Positives = 182/484 (37%), Gaps = 49/484 (10%)
Query: 131 YILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQI-V 189
+I T P A ++FPCF+ + L L +SN V S + +
Sbjct: 148 WIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKTSDHEKDDYVWT 207
Query: 190 KFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPI 249
F +TP M+ F I RT ++ P+ Y+ +++
Sbjct: 208 TFQQTPAMSVQKLAFSINRFTN-RTSAEIPKGPALTTWLRPKIADQGDYAISITPQIIVF 266
Query: 250 VEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLI 309
G YP K+D ++LP + + E+ GL+++ L + Q S QQV +
Sbjct: 267 FISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQR-STTRAKQQVASHV 325
Query: 310 VHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIST 369
E H W+ + ++ W + + + + +D + + + Q V+
Sbjct: 326 AQEFAHHWLSD---LENAALYWLHNGLSDYVSGFAVDNVEPAWRFHELSMVRQALAVLVE 382
Query: 370 DAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNRALAQIF- 428
D++ + + SL S + + K L R L +G + F AL
Sbjct: 383 DSKSSAYPM---------SLAYASKSSDTQANQKSALLFRMLHSLIGTQAFLNALRLYLQ 433
Query: 429 -------SESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRTPGIPIISV--NTDT 479
S + T + D + + +K ++ SWT PG P+I V N DT
Sbjct: 434 RSHKGSSSNQAFLWHTLQEESDNQMSLRQDIK---VSQLMDSWTMQPGYPLIRVVRNYDT 490
Query: 480 ERTTLEQHRFLLEKTDV---EDIPYHIPL---------FAVQSSGEDDTKNGLFTDRTLK 527
T+ Q RFL + + +PL F E T G T L
Sbjct: 491 NEVTVTQERFLRNPGKLMQKRQQCWWVPLTFATAGIDSFVSTLPSEWLTCQGRQTASPLI 550
Query: 528 LSE---PE--LIVNSGARGLYRVSYETDKCYELINEALKNSKISDLDLF---KIFIDLRS 579
L+E P+ ++ N R++Y+ ++ ++LI AL + S +D F ++ D+ +
Sbjct: 551 LNEVAQPDKWVVFNLRLATPCRITYD-ERNWQLIGNALSGTNASSIDRFTRAQLISDVLN 609
Query: 580 LIGS 583
L G+
Sbjct: 610 LAGA 613
>Hs4505029 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 611
Score = 73.9 bits (180), Expect = 1e-12
Identities = 92/375 (24%), Positives = 153/375 (40%), Gaps = 48/375 (12%)
Query: 124 TTGISDSYILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNT--SVENRSV 181
T+G Y+ + Q + R+I PC D P+ K Y ++ + + + E
Sbjct: 124 TSGKEHPYLFS-QCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDP 182
Query: 182 TDDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFD 241
D ++I KF + + +G LE + + + + + + Y F
Sbjct: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRT------LVWSEKEQVEKSAYEFS 236
Query: 242 TIVELLPIVEKRLGVDYPLEKLDVVLLP-FLSDMAMENWGLLTFQMNHLLLTPQALSDPS 300
+L I E LG Y + D+++LP MEN LTF LL ++LS+
Sbjct: 237 ETESMLKIAED-LGGPYVWGQYDLLVLPPSFPYGGMEN-PCLTFVTPTLLAGDKSLSN-- 292
Query: 301 VIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWF---ACDLL----DEHDND-G 352
+I HE+ H W GN ++ +WDH W NE + C L H N G
Sbjct: 293 -------VIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALG 345
Query: 353 YWSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQ 412
W +++N + T E T T+ V+D+ + A+ Y KG +LL L+
Sbjct: 346 GWG------ELQNSVKTFGE--THPFTK-LVVDLTDI-DPDVAYSSVPYEKGFALLFYLE 395
Query: 413 QSVGKE----NFNRALAQIFS-ESSTFHETCIKPMDIFRRMGEILKSENIANFYSSWTRT 467
Q +G F +A + FS +S T + F+ ++L + +++W +
Sbjct: 396 QLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVD----WNAWLYS 451
Query: 468 PGIPIISVNTDTERT 482
PG+P I N D T
Sbjct: 452 PGLPPIKPNYDMTLT 466
>CE28160 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 625
Score = 72.4 bits (176), Expect = 3e-12
Identities = 75/287 (26%), Positives = 117/287 (40%), Gaps = 23/287 (8%)
Query: 133 LATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFS 192
L + Q + ARSI PC D P+ K Y+ +T + + + DD F
Sbjct: 138 LFSQCQAIHARSIVPCMDTPSVKSTYEAEVTVPTGMTCLMSAIGQGSKGDDDTTTF--FY 195
Query: 193 KTPLMNTSYF-GFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVE 251
K P+ SY +G LE + D+ + P + A + F ++L E
Sbjct: 196 KQPVAIPSYLIAIVVGCLE--KRDISDRCAVWA----EPSVVDKAHWEFAETEDILASAE 249
Query: 252 KRLGVDYPLEKLDVVLLPFLSDMA-MENWGLLTFQMNHLLLTPQALS-DPSVIQQVRQLI 309
+ G Y + D+V LP MEN LTF LTP ++ D S++ +I
Sbjct: 250 EIAG-KYIWGRYDMVCLPPSFPFGGMEN-PCLTF------LTPTLIAGDRSLVS----VI 297
Query: 310 VHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQMENVIST 369
HE+ H W GN ++ SW+H W NE F + + ++ Y + ++I
Sbjct: 298 AHEIAHSWSGNLVTNSSWEHFWLNEGFTMFIERKICGRLVSEDYRQFMAFNGWTNSLIPA 357
Query: 370 DAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVG 416
E T + +I + AF Y KG +LL L+Q +G
Sbjct: 358 VYEQFTPTHQFTKLIQDHTNVDPDVAFSCVPYEKGSALLFYLEQKLG 404
>7294697 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 887
Score = 72.0 bits (175), Expect = 4e-12
Identities = 99/476 (20%), Positives = 197/476 (40%), Gaps = 53/476 (11%)
Query: 134 ATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISN-TSVENRSVTDDRKQI-VKF 191
AT +P +A ++FPCFD+P + Y +TL D K+ +SN VE + + + F
Sbjct: 148 ATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTF 207
Query: 192 SKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVE 251
+P + T + + LE + + + I V S H + E+ P +
Sbjct: 208 MGSPPLATQQVMWTLHQLEKVYSGPAAAGENITV-----WSRPHLAEKLAKVPEMTPNLF 262
Query: 252 KRLGV--DYPLE-------KLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVI 302
+ YPL K+D V+LP ++M G++ + + + S + +
Sbjct: 263 SKYETLFAYPLPKGADWGGKVDHVVLPRYTEM-YSGQGIMVYGEDIV------DSGQNGL 315
Query: 303 QQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVYLTQ 362
+ +++ + + QW G ++ + D + + + ++ D + Y ++ + T+
Sbjct: 316 ESLQETLAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVM-AMDKEAYNTTHLSKTR 374
Query: 363 MENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKENFNR 422
++ V+ D+ KSI DVK + K L+ L+ ++G + F +
Sbjct: 375 LD-VLYHDSLAKVKSI----ATDVK-----ESGHQKLRKKKMCLLIHMLKVALGDKLFLK 424
Query: 423 ALAQIFSESSTFHETCIKPMDIF----RRMGEILKSENIANFYSSWTRTPGIPIISVNTD 478
L + F + + + + F RR ++ ++ SW + PG P+++V D
Sbjct: 425 GLQEFFKRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRD 484
Query: 479 TER--TTLEQHRFLLEKTD----------VEDIPYHIPLFAVQSSGEDDTKNGLFTDRTL 526
+ T+ Q R+ + D V I ++ L V+ G + +
Sbjct: 485 DAKQIVTITQSRYYQKYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKNSRDILELSHI 544
Query: 527 KLSEPELIVNSGARGLYRVSYETDKCYELINEALKN--SKISDLDLFKIFIDLRSL 580
E L++N A RV Y++ +LI+EAL+ ++I +L ++ D SL
Sbjct: 545 ANPEDWLLINVDAAVPLRVFYDSYN-LQLISEALRQDFTQIPELSRIQLVDDALSL 599
>CE19614 [K] KOG1932 TATA binding protein associated factor
Length = 1086
Score = 70.1 bits (170), Expect = 1e-11
Identities = 102/441 (23%), Positives = 168/441 (37%), Gaps = 49/441 (11%)
Query: 75 QTVSFSSDDPL---NIADDTAELRISYIGKVNTIKTHRELTTGLFKTNFMSDTTGIS--- 128
Q S SS +P+ +A++ EL+I +V HR+ T G+
Sbjct: 149 QEKSISSLEPVLYEKLAENDYELQILIPKEVRKKIKHRKAVRLRVDTVVRDPPRGLQFVD 208
Query: 129 ----DSYILATHTQPVF-ARSIFPCFDEPNSKCKYQLTLTADDKF-KVISNTSVENRSVT 182
D ++ HT + AR C DEP+ ++LT + V S E R V+
Sbjct: 209 FNEHDCHVFTYHTPHISGAREWTVCLDEPDQLALWELTFELEPHLVPVASGELEEKREVS 268
Query: 183 DDRKQIVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDT 242
++ K KF +T + G+ IG + T + P ++H T D
Sbjct: 269 ENGKIRYKFHQTVPTSACNIGWAIGRFKLEPHPESPTIYTFSLPGLEP-FVNHTTMYLDK 327
Query: 243 IVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQAL----SD 298
+VE L E++L +P L VV + D E + + LL+ P A+
Sbjct: 328 MVEFL---EEKLSCRFPYPTLKVVFV----DQCTEEIQVYS----SLLIVPTAMLYHKKI 376
Query: 299 PSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEH--DNDGYWS- 355
V+Q+ RQ ++ + Q+ G IS W H W + A + ++ + W
Sbjct: 377 IDVVQEARQKLIFSIALQFFGCLISPAQWWHWWIPVSIARFLTSLYVETKLGTAEARWQL 436
Query: 356 ----SDV--YLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLR 409
DV Y Q ++ + E T K +D + + S + + KG +R
Sbjct: 437 KRAMDDVCDYEHQWGKIVLSPPEPTKKLPLH---VDPRHEYTASPLYVEAMLKKGFLTMR 493
Query: 410 SLQQSVGKENFNRALAQIFSESSTFHETCIKP---------MDIFRRMGEILKSENIANF 460
LQ+ +G E F R L ++ + E P + F R + + I +F
Sbjct: 494 MLQRRIGLEPFMRVLHRVLTVGLDMSEKKTTPAAWRHLLTTTESFFRSVISVTGKEIPSF 553
Query: 461 YSSWTRTPGIPIISVNTDTER 481
S + RT G +V D R
Sbjct: 554 LSQFVRTGGHAAFAVKFDFNR 574
>At5g13520 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 616
Score = 68.2 bits (165), Expect = 6e-11
Identities = 58/224 (25%), Positives = 98/224 (42%), Gaps = 32/224 (14%)
Query: 135 THTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFK-VISNTSVENR-SVTDDRKQ----- 187
T Q + ARSIFPC D P ++ +Y + + + V+S V R +V ++ K
Sbjct: 127 TQCQAIHARSIFPCQDTPAARIRYDVVMNIPNSLSAVMSARHVRRRLAVPEEAKHLEAGS 186
Query: 188 ------------IVKFSKTPLMNTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISH 235
+ +F+ + F F +G+L F + + T + A + +
Sbjct: 187 LGSSLWCGEDRVVEEFAMEQPIPPYLFAFAVGELGFREVGPRTRVYT---ESAAIEVLDA 243
Query: 236 ATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQA 295
A F +++ EK G DY E+ D+++LP + G+ +M + LTP
Sbjct: 244 AALEFAGTEDMIKQGEKLFG-DYEWERFDLLVLP----PSFPYGGMENPRM--VFLTPTV 296
Query: 296 LSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATW 339
+ + QV + HEL H W GN I+ + +H W NE F T+
Sbjct: 297 IKGDATGAQV---VAHELAHSWTGNLITNINNEHFWLNEGFTTY 337
>YNL045w [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 671
Score = 65.5 bits (158), Expect = 4e-10
Identities = 72/344 (20%), Positives = 137/344 (38%), Gaps = 39/344 (11%)
Query: 138 QPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKTPLM 197
+ + ARS+FPCFD P+ K + ++ + V S +E+ T I +F + +
Sbjct: 186 EAIHARSLFPCFDTPSVKSTFTASIESPLPV-VFSGIRIED---TSKDTNIYRFEQKVPI 241
Query: 198 NTSYFGFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKRLGVD 257
G GDL + T P +L + F+ VE +++ +
Sbjct: 242 PAYLIGIASGDLSSAPIGPRSTVYTEPFRL------KDCQWEFENDVEKFIQTAEKIIFE 295
Query: 258 YPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTPQALSDPSVIQQVRQ---LIVHELC 314
Y D+++ + ++ + + P++I R +I HEL
Sbjct: 296 YEWGTYDILV------------NVDSYPYGGMESPNMTFATPTLIAHDRSNIDVIAHELA 343
Query: 315 HQWMGNYISFDSWDHLWFNEAFATWFACDLLD--EHDNDGYWSSDVYLTQMENVISTDAE 372
H W GN ++ SW+H W NE + + ++ + ++S+ + + ++N I + +
Sbjct: 344 HSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNSIDSMKD 403
Query: 373 VTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSV-GKENFNRALAQIFSES 431
S V ++ DAF Y KG +LL L+ + GK F+ + F +
Sbjct: 404 PERFSTL---VQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKF 460
Query: 432 STFHETCIKPMD----IFRRMGEILKSENIANFYSSWTRTPGIP 471
+ + +D + EIL S + + +W PG+P
Sbjct: 461 AKKSLDTFQFLDTLYEFYPEKKEILDSVD----WETWLYKPGMP 500
>SPCC1322.05c [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 612
Score = 64.3 bits (155), Expect = 8e-10
Identities = 89/357 (24%), Positives = 138/357 (37%), Gaps = 46/357 (12%)
Query: 138 QPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVI-SNTSVENRSVTDDRKQIVKFSKTPL 196
Q + ARS PC D P+ K T K VI S + + + + K P+
Sbjct: 138 QAIHARSFIPCQDTPS--VKVPCTFKIRSKLPVIASGIPCGTANFCNGSLEYLFEQKNPI 195
Query: 197 MNTSYFGFCI--GDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKRL 254
SY FCI GDL + T P L A Y F+ +E ++L
Sbjct: 196 --PSYL-FCILSGDLASTNIGPRSSVYTEPGNLLA------CKYEFEHDMENFMEAAEQL 246
Query: 255 GVDYPLEKLDVVLLP-FLSDMAMENWGLLTFQMNHLLLTPQALS-DPSVIQQVRQLIVHE 312
+ Y + D V+LP MEN N TP ++ D S + +I HE
Sbjct: 247 TLPYCWTRYDFVILPPSFPYGGMEN-------PNATFATPTLIAGDRSNVN----VIAHE 295
Query: 313 LCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGYWSSDVY-----LTQMENVI 367
L H W GN ++ +SW W NE + +L + + L + ++
Sbjct: 296 LAHSWSGNLVTNESWQCFWLNEGMTVFLERKILGRLYGEPTRQFEAIIGWGELEESVKLL 355
Query: 368 STDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGISLLRSLQQSVGKEN-FNRALAQ 426
D+E T +I + DAF Y KG + L +++ +G + F L
Sbjct: 356 GEDSEYT-------KLIQNLEGRDPDDAFSTVPYEKGSNFLYEIERVIGGPSVFEPFLPF 408
Query: 427 IFSE--SSTFHETCIKP--MDIFRRMGEILKSENIANFYSSWTRTPGIPIISVNTDT 479
F + ST +E K + F +G K ++I + +W PG+P + + DT
Sbjct: 409 YFRKFAKSTVNEVKFKHALYEYFSPLGLASKLDSID--WDTWYHAPGMPPVKPHFDT 463
>Hs20537652 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 650
Score = 62.8 bits (151), Expect = 2e-09
Identities = 57/207 (27%), Positives = 88/207 (41%), Gaps = 23/207 (11%)
Query: 135 THTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKT 194
T Q V R+ FPCFD P K KY + D F T+V + S + R F +
Sbjct: 168 TQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGF-----TAVMSASTWEKRGPNKFFFQM 222
Query: 195 PLMNTSYF-GFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKR 253
SY IGDL + +V +++ P I A ++ ++E ++
Sbjct: 223 CQPIPSYLIALAIGDL--VSAEVGPRSRVWA----EPCLIDAAKEEYNGVIEEFLATGEK 276
Query: 254 LGVDYPLEKLDVVLLPFLSDMA-MENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIVHE 312
L Y + D++ +P MEN LTF LL ++L+D +I+HE
Sbjct: 277 LFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGDRSLAD---------VIIHE 326
Query: 313 LCHQWMGNYISFDSWDHLWFNEAFATW 339
+ H W GN ++ +W W NE F +
Sbjct: 327 ISHSWFGNLVTNANWGEFWLNEGFTMY 353
>Hs13443031 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 657
Score = 61.2 bits (147), Expect = 7e-09
Identities = 55/207 (26%), Positives = 89/207 (42%), Gaps = 24/207 (11%)
Query: 135 THTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKFSKT 194
T Q V R+ FPCFD P K KY + D F T+V + + R F +
Sbjct: 176 TQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGF-----TAVMSARPGEKRGPNKFFFQM 230
Query: 195 PLMNTSYF-GFCIGDLEFLRTDVKLKNKTIPVQLFAPQSISHATYSFDTIVELLPIVEKR 253
SY IGDL + +V +++ ++A + A ++ ++E ++
Sbjct: 231 CQPIPSYLIALAIGDL--VSAEVGPRSR-----VWAEPCLIDAAKEYNGVIEEFLATGEK 283
Query: 254 LGVDYPLEKLDVVLLPFLSDMA-MENWGLLTFQMNHLLLTPQALSDPSVIQQVRQLIVHE 312
L Y + D++ +P MEN LTF LL ++L+D +I+HE
Sbjct: 284 LFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGDRSLAD---------VIIHE 333
Query: 313 LCHQWMGNYISFDSWDHLWFNEAFATW 339
+ H W GN ++ +W W NE F +
Sbjct: 334 ISHSWFGNLVTNANWGEFWLNEGFTMY 360
>At1g63770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 964
Score = 55.8 bits (133), Expect = 3e-07
Identities = 73/320 (22%), Positives = 121/320 (37%), Gaps = 56/320 (17%)
Query: 234 SHATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQMNHLLLTP 293
+HA YS ++ E G++Y L+ ++V +P + AMEN L F +L +P
Sbjct: 305 AHAMYSLKAAMKW---DEDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASP 361
Query: 294 QALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLDEHDNDGY 353
+ +D + +I HE H W GN ++ W L E + D
Sbjct: 362 ETATDADYAA-ILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVF----------RDQE 410
Query: 354 WSSDVYLTQMENVISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHK---------- 403
+SSD+ ++ + A+V+ I Q + + PH Y K
Sbjct: 411 FSSDMGSRTVKRI----ADVSKLRIYQFP----QDAGPMAHPVRPHSYIKVYEKVWLFTN 462
Query: 404 ------GISLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILKSENI 457
G ++R + +G + F + + F TC D F M + + +
Sbjct: 463 SVLLYAGAEVVRMYKTLLGTQGFRKGIDLYFERHDEQAVTC---EDFFAAMRD-ANNADF 518
Query: 458 ANFYSSWTRTPGIPIISV----NTDTERTTLEQHRFLLEKTDVEDIPYHIPLF------A 507
ANF W G P++ V N D +L +F E P P F
Sbjct: 519 ANFL-QWYSQAGTPVVKVVSSYNADARTFSL---KFSQEIPPTPGQPTKEPTFIPVVVGL 574
Query: 508 VQSSGEDDTKNGLFTDRTLK 527
+ SSG+D T + + D T++
Sbjct: 575 LDSSGKDITLSSVHHDGTVQ 594
>Hs17472410 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 365
Score = 55.1 bits (131), Expect = 5e-07
Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 132 ILATHTQPVFARSIFPCFDEPNSKCKYQLTLTADDKFKVISNTSVENRSVTDDRKQIVKF 191
I AT +P AR FPCFD+PN K Y +++T +++ +S+ V DD+ F
Sbjct: 242 IAATDHEPTDARKFFPCFDKPNKKATYTISVTHPKEYEALSHMPVAKEESVDDKWNQTTF 301
Query: 192 SKTPLMNTSYFGFCIGDLEFLRT----------DVKLKNKTIPVQLFAPQSISH 235
K+ M+ F + ++T L +TI + +F P ++S+
Sbjct: 302 KKSVPMSMYLVCFAVHQFHTVKTISDIGKPEKASTALLEETIALGIFYPAALSN 355
>7300975 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1114
Score = 52.8 bits (125), Expect = 2e-06
Identities = 57/265 (21%), Positives = 108/265 (40%), Gaps = 17/265 (6%)
Query: 228 FAPQSIS-HATYSFDTIVELLPIVEKRLGVDYPLEKLDVVLLPFLSDMAMENWGLLTFQM 286
+AP+ + +++ T ++L ++ L + YPL K+D V LP L + + GL+T +
Sbjct: 439 YAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKT 498
Query: 287 NHLLLTPQALSDPSVIQQVRQLIVHELCHQWMGNYISFDSWDHLWFNEAFATWFACDLLD 346
+ L S+ +R I + Q+ G S +W E + L
Sbjct: 499 SFLTDPSSITSEQYQFSALR--IAEAMVRQFFGGITSRKVLKDVWLWEGLIQYLGIHALA 556
Query: 347 EHDNDGYWSSDVYLTQMEN-VISTDAEVTTKSITQGSVIDVKSLQSTSDAFEPHIYHKGI 405
+ + ++YL +M + DA SI G+ D + E K
Sbjct: 557 PL-QETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNN--------EEFFVQKTA 607
Query: 406 SLLRSLQQSVGKENFNRALAQIFSESSTFHETCIKPMDIFRRMGEILK-SENIANFYSSW 464
++ L ++G++ F L F + + F +P D++ + S+NI + + W
Sbjct: 608 AIFSMLHTAIGEDRFRGCLGS-FLKVNRFRTA--EPTDLWTICTKKANGSKNIKDMMTLW 664
Query: 465 TRTPGIPIISVNTDTERTTLEQHRF 489
T PG P+++V ++ Q F
Sbjct: 665 THQPGFPLLTVTKMGNSISISQRPF 689
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,005,434
Number of Sequences: 60738
Number of extensions: 2231611
Number of successful extensions: 5812
Number of sequences better than 1.0e-05: 56
Number of HSP's better than 0.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 5576
Number of HSP's gapped (non-prelim): 72
length of query: 895
length of database: 30,389,216
effective HSP length: 115
effective length of query: 780
effective length of database: 23,404,346
effective search space: 18255389880
effective search space used: 18255389880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)