ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2145 good D KOG2360 Cell cycle control, cell division, chromosome partitioning Proliferation-associated nucleolar protein (NOL1)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2145 753364 751892 -491
(491 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL022c [D] KOG2360 Proliferation-associated nucleolar protein ... 620 e-177
SPAC2C4.06c [D] KOG2360 Proliferation-associated nucleolar prote... 239 5e-63
Hs8922322 [D] KOG2360 Proliferation-associated nucleolar protein... 165 2e-40
CE25405 [D] KOG2360 Proliferation-associated nucleolar protein ... 139 1e-32
CE25404_3 [D] KOG2360 Proliferation-associated nucleolar protein... 139 1e-32
At5g26180 [D] KOG2360 Proliferation-associated nucleolar protein... 137 4e-32
ECU07g0320 [D] KOG2360 Proliferation-associated nucleolar protei... 116 7e-26
7300487 [D] KOG2360 Proliferation-associated nucleolar protein ... 103 4e-22
7300488 [D] KOG2360 Proliferation-associated nucleolar protein ... 100 8e-21
Hs14149837 [D] KOG2360 Proliferation-associated nucleolar protei... 97 5e-20
CE28259 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleol... 64 7e-10
YNL061w [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleol... 63 1e-09
Hs20473687 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucl... 62 2e-09
At5g55920 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucle... 60 6e-09
Hs21717803 [D] KOG2360 Proliferation-associated nucleolar protei... 57 8e-08
Hs5453792 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucle... 56 1e-07
Hs20556018 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucl... 56 1e-07
ECU01g1080 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucl... 55 2e-07
7303448 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleol... 55 3e-07
SPBP8B7.20c [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nuc... 54 7e-07
>YNL022c [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 490
Score = 620 bits (1599), Expect = e-177
Identities = 308/497 (61%), Positives = 384/497 (76%), Gaps = 13/497 (2%)
Query: 1 MEFYRDATWVLEFVEQELSKDKRVAGSLQTLVLTSCKRYKLKTNPRHIYAIVSSTWQYRE 60
M FYRDATWVLE +E+E +K+ R++GS+QTLVL SCKRYKLK+NP+HIYA++ S W+Y+
Sbjct: 1 MNFYRDATWVLEDIEKEAAKE-RISGSMQTLVLKSCKRYKLKSNPKHIYAVLDSCWKYKP 59
Query: 61 YLDKIIKKSGILEDVPKKKGKPLFNKDTIRLLVHDLLLSKSKRIQMGKHPIKTFILKHQT 120
YL+K++KK+ ILED+PKKKGKPLF++ T+ LL HDLLLSK KRIQMGKHPIK ++LK ++
Sbjct: 60 YLEKVMKKAHILEDIPKKKGKPLFSRLTLLLLCHDLLLSKQKRIQMGKHPIKDYVLKFKS 119
Query: 121 RLKAEXXXXXXXXXXXXXXQLIKTDD-GEDVTPVRWIRINPILVKER--YDDVLAELNKK 177
L +E +L+ ++D D+ PVRWIRINP+ + VLAEL KK
Sbjct: 120 PLHSEMVKLKLKLKVRELSELVLSEDISNDLPPVRWIRINPLKCHPNGETEPVLAELRKK 179
Query: 178 FPQRVNSWKQIVPGSIYYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILN 237
F +V+ W ++VPGSIYYDE+IPNLFGIHP DKIT+HE YK GKIIIQDRASCFPAHILN
Sbjct: 180 FTLKVDKWSELVPGSIYYDEFIPNLFGIHPSDKITAHELYKHGKIIIQDRASCFPAHILN 239
Query: 238 PNSTDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGC 297
P +D+VID+C+APGNKTTH A++I+ + K ++ +I+AFEKDPERAK LQ M+ AGC
Sbjct: 240 PGPSDIVIDSCSAPGNKTTHTASYIYPE-PPKDNNTRIYAFEKDPERAKVLQKMIKIAGC 298
Query: 298 AKGVKIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQ 357
+ + ++VGDFTKL PE +++VT FIVDPSCSGSGIFGRK D N K + +D
Sbjct: 299 SPNISVNVGDFTKLATPEKYKDVTCFIVDPSCSGSGIFGRKFFDSFNRRKI---DDKDDD 355
Query: 358 TSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENER 417
+ P EQE+ F +++L+ RLAKLSSFQ+Q+VKHAMSFP+AKKI YSTCSIHAEENER
Sbjct: 356 GGIVPDEQEE--FIAKEELQTRLAKLSSFQFQMVKHAMSFPAAKKIVYSTCSIHAEENER 413
Query: 418 VVIDLLLDSKVKEWGWKVRKRTGVIPTWPRRGWTSEFEEVF---PKEEAKELAEGCIRAL 474
VVIDLLLD V+EWGWKV + VIP+WPRRG EFEEVF + ++LAEGCIRAL
Sbjct: 414 VVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEFEEVFRDGVTYDPQQLAEGCIRAL 473
Query: 475 PKEDGGIGFFAVCFERD 491
PK DGGIGFFAVCFERD
Sbjct: 474 PKSDGGIGFFAVCFERD 490
>SPAC2C4.06c [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 455
Score = 239 bits (611), Expect = 5e-63
Identities = 181/496 (36%), Positives = 248/496 (49%), Gaps = 98/496 (19%)
Query: 1 MEFYRDATWVLEFVEQELSKDKRVAGSLQTLVLTSCKRYKLKTNPRHIYAIVSSTWQYRE 60
M+FY A +L +LSK K GS++ L S K +P+ YA+V T +Y+
Sbjct: 1 MDFYNHAANILS----DLSKKK---GSIKQLAFNSKKH-----DPKRTYALVCETLKYKP 48
Query: 61 YLDKIIKKSGILEDVPKKKGKPLFNKDTIRLLVHDLLLSKSKRIQMGKHPIKTFILKHQT 120
LD+II +S ++ R+LVHDLL+SK + + + PIK IL+H+T
Sbjct: 49 VLDEIIARSDCF-----------LKENLARVLVHDLLMSK-RGLSISNGPIKECILRHKT 96
Query: 121 RLKAEXXXXXXXXXXXXXXQLIKTDDGEDVTPVRWIRINPILVKERYDDVLAELNKKFPQ 180
RL AE +L + V+ RW+RIN I K D+VL L
Sbjct: 97 RLNAEFVKLKVKKGVKSHEELALKNP---VSLPRWLRINTI--KSTKDEVLQGLGL---D 148
Query: 181 RVNSWKQIVPGSIYYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNS 240
+V+S +++ P Y D+ + NL I P I + YK GK+IIQD+ASCFPA +L +
Sbjct: 149 KVSSIEELGPDKFYIDDCVENLIAIDPSFPIVENSLYKEGKVIIQDKASCFPAAVLAGLT 208
Query: 241 TDV--VIDACAAPGNKTTHVAA-----HIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVA 293
V +ID CAAPGNKTTH+AA HIF AFE+D +R +TL+ MV
Sbjct: 209 GHVGDIIDGCAAPGNKTTHLAACFPKSHIF-------------AFERDAKRVQTLRKMVG 255
Query: 294 TAGCAKGVKIHVGDFTKLG-KPELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSN 352
+G A V I DFT K +L++NVT ++DPSCSGSGI
Sbjct: 256 ISG-ANNVTIEHQDFTLTDPKSDLYRNVTHILLDPSCSGSGI------------------ 296
Query: 353 TDEDQTSVEPVEQEKELFEKEQDL---KNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCS 409
V ++ L EQD+ RL L SFQ I+KHA+ FP+ + + YSTCS
Sbjct: 297 ----------VSRQDYLLGNEQDVTEDTERLENLCSFQSTILKHALQFPNCRHVTYSTCS 346
Query: 410 IHAEENERVVIDLLLDSKVKEWGWKVRKRTGVIPTWPRRGWTSEFEEVFPKEEAK-ELAE 468
+H ENE+VV ++L +E WK T +P W RG P+ A+ +AE
Sbjct: 347 VHRLENEQVVCEVL----SQEPDWKCNSLTKTLPNWKTRG--------IPEYCAQPSMAE 394
Query: 469 GCIRALPKEDGGIGFF 484
G IR P G IGFF
Sbjct: 395 GMIRCKPGAGGTIGFF 410
>Hs8922322 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 429
Score = 165 bits (417), Expect = 2e-40
Identities = 153/499 (30%), Positives = 231/499 (45%), Gaps = 84/499 (16%)
Query: 1 MEFYRDATWVLEFVEQELSKDKRVAGSLQTLVLTSCKRYKLKTNPRHIYAIVSSTWQYRE 60
M Y A VL VE GS++ LV +S + N + +YA+V T +Y
Sbjct: 1 MGLYAAAAGVLAGVESR-------QGSIKGLVYSSNFQ-----NVKQLYALVCETQRYSA 48
Query: 61 YLDKIIKKSGILEDVPKKKGKPLFNKDTIRLLVHDLLLSKSKRIQMGKHPIKTFILKHQT 120
LD +I +G+L +KK +P K +LV++LLL K R G+ K + +HQ
Sbjct: 49 VLDAVIASAGLLR--AEKKLRPHLAK----VLVYELLLGKGFRGGGGRW--KALLGRHQA 100
Query: 121 RLKAEXXXXXXXXXXXXXXQLIKTDD--GEDVTPVRWIRINPILVKERYDDVLAELNKK- 177
RLKAE L++ G R++R+N + K DDV+ ++
Sbjct: 101 RLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTL--KTCSDDVVDYFKRQG 158
Query: 178 --FPQRVNSWKQI--VPGSIYY-DEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFP 232
+ R +S + + G + D +P L + H Y+ G +I+QDRASC P
Sbjct: 159 FSYQGRASSLDDLRALKGKHFLLDPLMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLP 218
Query: 233 AHILNPNSTDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMV 292
A +L+P VIDACAAPGNKT+H+AA + + KI AF+ D +R ++ ++
Sbjct: 219 AMLLDPPPGSHVIDACAAPGNKTSHLAALL-------KNQGKIFAFDLDAKRLASMATLL 271
Query: 293 ATAGCAKGVKIHVGDFTKLGKPE-LFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSS 351
A AG ++ DF + + + V ++DPSCSGSG+ R+ L + G+
Sbjct: 272 ARAG-VSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGMPSRQ------LEEPGAG 324
Query: 352 NTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIH 411
+ PV RL L+ FQ + + HA++FPS +++ YSTCS+
Sbjct: 325 -------TPSPV---------------RLHALAGFQQRALCHALTFPSLQRLVYSTCSLC 362
Query: 412 AEENERVVIDLLLDSKVKEWGWKVRKRTGVIPTWPRRGWTSEFEEVFPKEEAKELAEGCI 471
EENE VV D L + + +P WP RG ++ FP AE C+
Sbjct: 363 QEENEDVVRDALQQNP------GAFRLAPALPAWPHRGLST-----FPG------AEHCL 405
Query: 472 RALPKEDGGIGFFAVCFER 490
RA P+ GFF ER
Sbjct: 406 RASPETTLSSGFFVAVIER 424
>CE25405 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 469
Score = 139 bits (349), Expect = 1e-32
Identities = 114/370 (30%), Positives = 172/370 (45%), Gaps = 55/370 (14%)
Query: 143 KTDDG-EDVTPVRWIRINPILVKERYDDVLAELN------------KKFPQRVNSWKQIV 189
+ DDG + + R+ RIN + K D+ + L + F + V K
Sbjct: 128 EADDGMKKIQIPRYARINTL--KWTADEAMKTLETEKWKILGTLKPENFAEMVTKMKD-- 183
Query: 190 PGSIYYDEYIPNLFGIHPG-DKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDAC 248
+Y D ++ NL P + ++ +I+QD+ASC PA +LNP V D C
Sbjct: 184 -DEVYVDPHVENLIIFAPNIQNFYEYWMVEQRYLILQDKASCLPAFLLNPRPGSQVFDTC 242
Query: 249 AAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDF 308
AAPG KT+H AA + + K+ A ++ +R T++ ++ + A GDF
Sbjct: 243 AAPGMKTSHAAAIM-------ENQGKVWAMDRAADRVATMKQLLDASKVAIASSF-CGDF 294
Query: 309 TKLGKPEL-FQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEK 367
K + F V IVDP CSGSGI K +D++ TG + E ++ ++ K
Sbjct: 295 LKTDVTDKKFSKVKFAIVDPPCSGSGIV--KRMDEI----TGGNAEKERLEKLKNLQVHK 348
Query: 368 ELFE-------KEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVVI 420
L E K + KL I+KHA+ P K+ YSTCS+H EENE+VV
Sbjct: 349 NLDLLKMCWKCSENCFKKKTKKLIENDAMILKHALKLPGLKRAVYSTCSVHEEENEQVVD 408
Query: 421 DLLLDSKVKEWGWKVRKRTGVIPTWPRRGWTSEFEEVFPKEEAKELAEGCIRALPKEDGG 480
++LLD+ V++ + ++K V+P W RG + E+ E C+RA PK
Sbjct: 409 EVLLDTYVRQ-NYVLKK--NVLPEWTYRGL-----------KTYEVGEHCLRANPKVTLT 454
Query: 481 IGFFAVCFER 490
GFF FER
Sbjct: 455 NGFFVAVFER 464
>CE25404_3 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 436
Score = 139 bits (349), Expect = 1e-32
Identities = 114/370 (30%), Positives = 172/370 (45%), Gaps = 55/370 (14%)
Query: 143 KTDDG-EDVTPVRWIRINPILVKERYDDVLAELN------------KKFPQRVNSWKQIV 189
+ DDG + + R+ RIN + K D+ + L + F + V K
Sbjct: 95 EADDGMKKIQIPRYARINTL--KWTADEAMKTLETEKWKILGTLKPENFAEMVTKMKD-- 150
Query: 190 PGSIYYDEYIPNLFGIHPG-DKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDAC 248
+Y D ++ NL P + ++ +I+QD+ASC PA +LNP V D C
Sbjct: 151 -DEVYVDPHVENLIIFAPNIQNFYEYWMVEQRYLILQDKASCLPAFLLNPRPGSQVFDTC 209
Query: 249 AAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDF 308
AAPG KT+H AA + + K+ A ++ +R T++ ++ + A GDF
Sbjct: 210 AAPGMKTSHAAAIM-------ENQGKVWAMDRAADRVATMKQLLDASKVAIASSF-CGDF 261
Query: 309 TKLGKPEL-FQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEK 367
K + F V IVDP CSGSGI K +D++ TG + E ++ ++ K
Sbjct: 262 LKTDVTDKKFSKVKFAIVDPPCSGSGIV--KRMDEI----TGGNAEKERLEKLKNLQVHK 315
Query: 368 ELFE-------KEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVVI 420
L E K + KL I+KHA+ P K+ YSTCS+H EENE+VV
Sbjct: 316 NLDLLKMCWKCSENCFKKKTKKLIENDAMILKHALKLPGLKRAVYSTCSVHEEENEQVVD 375
Query: 421 DLLLDSKVKEWGWKVRKRTGVIPTWPRRGWTSEFEEVFPKEEAKELAEGCIRALPKEDGG 480
++LLD+ V++ + ++K V+P W RG + E+ E C+RA PK
Sbjct: 376 EVLLDTYVRQ-NYVLKK--NVLPEWTYRGL-----------KTYEVGEHCLRANPKVTLT 421
Query: 481 IGFFAVCFER 490
GFF FER
Sbjct: 422 NGFFVAVFER 431
>At5g26180 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 532
Score = 137 bits (345), Expect = 4e-32
Identities = 130/471 (27%), Positives = 211/471 (44%), Gaps = 80/471 (16%)
Query: 21 DKRVAGSLQTLVLTSCKRYKLKTNPRHIYAIVSSTWQYREYLDKIIKKSGILEDVPKKKG 80
++R S+++LVL+ R N R +A+V T +Y + ++ + +L K++
Sbjct: 115 ERRAVASIKSLVLSPSVR-----NKRGTFALVCETLKYLTVIKDVLDIANVLNSKWKRQE 169
Query: 81 KPLFNKDTIRLLVHDLLLSKSKRIQMGKHPIKTFILKHQTRLKAEXXXXXXXXXXXXXXQ 140
+F ++ +D+L K +G + F+++H+ L + Q
Sbjct: 170 PLVF------IVCYDILFGKDTP-SIGD--AEKFLMRHKEALLSGLATLLVRKKVDSVDQ 220
Query: 141 LIKTDDGEDVTPVRWIRINPILVKERYDDVLAELNKKFPQRVNSWKQIVPGSIYYDEYIP 200
L+ + + P R++R+N + K D + EL K + ++ DE +P
Sbjct: 221 LLGSKLTGHLKP-RYVRVNTL--KMDVDSAVQELEKHY-------------TVQKDETVP 264
Query: 201 NLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAA 260
+L + PG + +H G+I +Q +AS A L P + V+DAC+APGNKT H+AA
Sbjct: 265 DLLVLPPGSDLHAHRLVANGRIFLQGKASSMVAAALQPQAGWEVLDACSAPGNKTIHLAA 324
Query: 261 HIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLG-KPELFQN 319
+ G KI A E + ER K L+ + + +++ GDF L K F
Sbjct: 325 LMEG-------QGKIIACELNEERVKRLEHTIKLS----DIEVCHGDFLGLNPKDPSFAK 373
Query: 320 VTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNR 379
+ ++DPSCSGSG + +D + S + +N + D R
Sbjct: 374 IRAILLDPSCSGSGTITDR-LDHLLPSHSEDNNMNYDSM--------------------R 412
Query: 380 LAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVVIDLLLDSKVKEWGWKVRKRT 439
L KL+ FQ + + HA+SFP +++ YSTCSI+ ENE VV +L G+K+
Sbjct: 413 LHKLAVFQKKALAHALSFPKVERVVYSTCSIYQIENEDVVSSVL--PLASSLGFKL---A 467
Query: 440 GVIPTWPRRGWTSEFEEVFPKEEAKELAEGCIRALPKEDGGIGFFAVCFER 490
P W RRG VF +E +R P ED GFF F R
Sbjct: 468 TPFPQWQRRGL-----PVFAG------SEHLLRMDPVEDKE-GFFIALFVR 506
>ECU07g0320 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 364
Score = 116 bits (291), Expect = 7e-26
Identities = 89/297 (29%), Positives = 128/297 (42%), Gaps = 64/297 (21%)
Query: 194 YYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGN 253
Y + ++ I I E YK GK +IQ+ +SC PAHIL+P VID C+APGN
Sbjct: 130 YEKSCVDGVYKILDSKNIVFSEGYKNGKFVIQNISSCLPAHILDPEEGSRVIDTCSAPGN 189
Query: 254 KTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLGK 313
KT+ +A ++ KI+AFE+ RA+TL+ + G ++ DF
Sbjct: 190 KTSQLAM-------IMRNTGKIYAFERSKNRAETLRAQLFKLG-VSNTEVVEDDFMN-AN 240
Query: 314 PELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKE 373
PE F+ + + DPSCSGSG+ +D
Sbjct: 241 PEDFEGIRYILCDPSCSGSGMHLGYKMD-------------------------------- 268
Query: 374 QDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVVIDLLLDSKVKEWGW 433
K R+ L SFQ +IV+HA+ F +K+ YS CS H EE E VV ++L S+ +
Sbjct: 269 ---KERIEGLKSFQIEIVRHALRF-RPEKLVYSVCSDHREEGEEVVEEILRSSEYELENI 324
Query: 434 KVRKRTGVIPTWPRRGWTSEFEEVFPKEEAKELAEGCIRALPKEDGGIGFFAVCFER 490
+ W+S F ++ +R E G IGFF F R
Sbjct: 325 SM-------------FWSSAHSSGF------SFSQDVVRCRRDESGAIGFFIALFVR 362
>7300487 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 433
Score = 103 bits (258), Expect = 4e-22
Identities = 105/395 (26%), Positives = 170/395 (42%), Gaps = 91/395 (23%)
Query: 46 RHIYAIVSSTWQYREYLDKIIKKSGILEDVPKKKGKPLFNKDTIRLLVHDLLLSKSKRIQ 105
R ++ ++ + R L+K I+++G+L D P F+ ++LV +LL + K +
Sbjct: 44 RSLHTVLKKFSENRVALEKAIEETGLLRD------NPSFDPSLAKILVTELLFGR-KELN 96
Query: 106 MGKHPIKTFILKHQTRLKAEXXXXXXXXXXXXXXQLIKTDDGEDVTPVRWIRINPILVKE 165
P++T + ++ RL ++ P R++RIN L
Sbjct: 97 GESKPVQT-VRSYKDRLLNSIRDFGVQR--------------KEPNP-RYVRINTNLYS- 139
Query: 166 RYDDVLAELNKKFPQRVNSWKQI-VPGSIYYDEYIPNLFGIHPGDKITS----------- 213
+ L L+K + W++ +P Y +++ + + + +T
Sbjct: 140 -LAEALDYLHK------SDWRRKELPADASYADFLTAIKSLAENEFMTDLHVEGVLIFPA 192
Query: 214 --------HEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAAHIFGD 265
H + I+Q++A+C A +L P S V+D CAAPG KT H+
Sbjct: 193 KWSNYWVRHPLVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHIC------ 246
Query: 266 VDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLGKPELFQNVTGFIV 325
+ + I++ E+D R TL + AGC VK +GD L PE F +V +V
Sbjct: 247 -NVMQNKGCIYSVEQDHVRYNTLCEITKDAGC-DIVKPILGDALNL-TPERFPDVEYILV 303
Query: 326 DPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSS 385
DPSCSGSG+ R + EP E + RL KL
Sbjct: 304 DPSCSGSGMQNRMTV------------------CDEPKEDK------------RLQKLQG 333
Query: 386 FQYQIVKHAM-SFPSAKKICYSTCSIHAEENERVV 419
Q +I+ HAM +FP+ K+I Y TCS+ EENE+VV
Sbjct: 334 LQIKILSHAMGAFPNVKRIAYCTCSLWKEENEQVV 368
>7300488 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 383
Score = 99.8 bits (247), Expect = 8e-21
Identities = 72/200 (36%), Positives = 99/200 (49%), Gaps = 40/200 (20%)
Query: 221 KIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEK 280
+ I+Q++A+C A +L P S V+D CAAPG KT H+ + + I++ E+
Sbjct: 158 RFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHIC-------NVMQNKGCIYSVEQ 210
Query: 281 DPERAKTLQMMVATAGCAKGVKIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIFGRKAI 340
D R TL + AGC VK +GD L PE F +V +VDPSCSGSG+ R +
Sbjct: 211 DHVRYNTLCEITKDAGC-DIVKPILGDALNL-TPERFPDVEYILVDPSCSGSGMQNRMTV 268
Query: 341 DKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAM-SFPS 399
EP E + RL KL Q +I+ HAM +FP+
Sbjct: 269 ------------------CDEPKEDK------------RLQKLQGLQIKILSHAMGAFPN 298
Query: 400 AKKICYSTCSIHAEENERVV 419
K+I Y TCS+ EENE+VV
Sbjct: 299 VKRIAYCTCSLWKEENEQVV 318
>Hs14149837 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 315
Score = 97.1 bits (240), Expect = 5e-20
Identities = 85/293 (29%), Positives = 131/293 (44%), Gaps = 54/293 (18%)
Query: 199 IPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHV 258
+P L + H Y+ G +I+QDRASC PA +L+P + KT+H+
Sbjct: 1 MPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPRRAPMSWMPVPPQAIKTSHL 60
Query: 259 AAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLGKPE-LF 317
AA + + KI AF+ D R ++ ++A AG ++ DF + + +
Sbjct: 61 AALL-------KNQGKIFAFDLDARRLASMATLLAWAG-VSCCELAEEDFLAVSPLDPRY 112
Query: 318 QNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLK 377
+ V ++DPSCSGSG+ R+ L + G+ + PV
Sbjct: 113 REVHYVLLDPSCSGSGMPSRQ------LEEPGAG-------TPSPV-------------- 145
Query: 378 NRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVVIDLLLDSKVKEWGWKVRK 437
RL L+ FQ + + HA++FPS +++ YS CS+ EENE +V D L + +
Sbjct: 146 -RLHALAGFQQRALCHALTFPSLQRLVYSMCSLCQEENEDMVQDALQQNP------DAFR 198
Query: 438 RTGVIPTWPRRGWTSEFEEVFPKEEAKELAEGCIRALPKEDGGIGFFAVCFER 490
+P P RG ++ FP AE C+RA PK GFF ER
Sbjct: 199 LAPALPARPHRGLST-----FPG------AEHCLRASPKTTLSGGFFVAVIER 240
>CE28259 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 664
Score = 63.5 bits (153), Expect = 7e-10
Identities = 73/281 (25%), Positives = 117/281 (40%), Gaps = 72/281 (25%)
Query: 156 IRINPILVKERYDDVLAELNKKFPQR------VNSWKQIVPGSIYYDEYIPNLFGIHPGD 209
IR N + VK R +L K R W ++ G + YD +P
Sbjct: 233 IRANSLKVKRR------DLAKNLINRGMNVDPAADWTKV--GLVVYDSQVP--------- 275
Query: 210 KITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAAHIFGDVDTK 269
+ + +Y G +IQ S P L P D V+D C+APG KT+H+AA
Sbjct: 276 -VGATPEYLAGHYMIQGLNSLLPVMALAPQPGDRVLDMCSAPGGKTSHIAA-------LM 327
Query: 270 VDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVG--DFTKLGKPELFQNVTGFIVDP 327
+S + A + + R + + + G V ++G +F+K+ +P F + ++D
Sbjct: 328 KNSGVLFANDANFTRCRAIIGNLHRLGVNNTVVCNLGGEEFSKI-RPNGFDRI---LLDA 383
Query: 328 SCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQ 387
CSG+G+ + K S T +D QD++ R + Q
Sbjct: 384 PCSGTGV----------IWKDQSVKTSKD----------------SQDVQRR----HTMQ 413
Query: 388 YQIVKHAM-----SFPSAKKICYSTCSIHAEENERVVIDLL 423
Q++ A+ + P+ + YSTCS+ EENE VV LL
Sbjct: 414 RQLILSALDSLDANSPNGGYLVYSTCSVLVEENEAVVNFLL 454
>YNL061w [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 618
Score = 62.8 bits (151), Expect = 1e-09
Identities = 57/240 (23%), Positives = 103/240 (42%), Gaps = 47/240 (19%)
Query: 180 QRVNSWKQIVPGSIYYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPN 239
Q + SW ++ G +D +P I + +Y G I+Q +S P L+P+
Sbjct: 297 QPIGSWTKV--GLQIFDSQVP----------IGATPEYLAGHYILQAASSFLPVIALDPH 344
Query: 240 STDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAK 299
+ ++D AAPG KTT+++A + ++ + A + + R K+L + GC
Sbjct: 345 ENERILDMAAAPGGKTTYISAMM-------KNTGCVFANDANKSRTKSLIANIHRLGCTN 397
Query: 300 GVKIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTS 359
+ V ++ P++ ++D CSG+G+ G+ KV S T++D
Sbjct: 398 TI---VCNYDAREFPKVIGGFDRILLDAPCSGTGVIGKDQSVKV-------SRTEKDFIQ 447
Query: 360 VEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVV 419
+ ++ K+L D + +K I YSTCS+ EE+E V+
Sbjct: 448 IPHLQ--KQLLLSAIDSVDCNSKHGGV----------------IVYSTCSVAVEEDEAVI 489
>Hs20473687 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 469
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/203 (28%), Positives = 94/203 (46%), Gaps = 39/203 (19%)
Query: 222 IIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAA--HIFGDVDTKVDSVKIHAFE 279
+ +Q+ S +H+LNP + ++D CAAPG KTTH+AA H G+V +D + + E
Sbjct: 216 LFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEV-IALDKI-FNKVE 273
Query: 280 KDPERAKTLQMMVATAGC---AKGVKIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIFG 336
K + A L + A C K VK+ + + T+ P L ++ ++D CSG G
Sbjct: 274 KIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMG--- 330
Query: 337 RKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAMS 396
+ N++ T S ++ S +P+++ KL + Q++K
Sbjct: 331 ----QRPNMACTWSV---KEVASYQPLQR----------------KLFTAAVQLLK---- 363
Query: 397 FPSAKKICYSTCSIHAEENERVV 419
+ YSTC+I ENE V
Sbjct: 364 --PEGVLVYSTCTITLAENEEQV 384
>At5g55920 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 682
Score = 60.5 bits (145), Expect = 6e-09
Identities = 62/253 (24%), Positives = 100/253 (39%), Gaps = 55/253 (21%)
Query: 182 VNSWKQIVPGSIYYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNST 241
++ W ++ G + YD +P I + +Y G ++Q +S P L P
Sbjct: 313 LSKWSKV--GLVIYDSQVP----------IGATPEYLAGYYMLQGASSFLPVMALAPREN 360
Query: 242 DVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGV 301
+ ++D AAPG KTT++AA ++ I+A E R K+L + G +
Sbjct: 361 ERIVDVAAAPGGKTTYIAA-------LMKNTGLIYANEMKVPRLKSLTANLHRMGVTNTI 413
Query: 302 KIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSVE 361
+ D +L K V ++D CSG+GI + + V ++KT
Sbjct: 414 VCNY-DGRELPKVLGQNTVDRVLLDAPCSGTGIISKD--ESVKITKT------------- 457
Query: 362 PVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAMSFPSAKK-----ICYSTCSIHAEENE 416
+ + K + Q Q++ A+ A I YSTCSI ENE
Sbjct: 458 ---------------MDEIKKFAHLQKQLLLAAIDMVDANSKTGGYIVYSTCSIMVTENE 502
Query: 417 RVVIDLLLDSKVK 429
V+ L VK
Sbjct: 503 AVIDYALKKRDVK 515
>Hs21717803 [D] KOG2360 Proliferation-associated nucleolar protein (NOL1)
Length = 154
Score = 56.6 bits (135), Expect = 8e-08
Identities = 39/112 (34%), Positives = 55/112 (48%), Gaps = 17/112 (15%)
Query: 379 RLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVVIDLLLDSKVKEWGWKVRKR 438
RL L+ FQ + + HA++FPS +++ YS CS+ EENE +V D L + +
Sbjct: 18 RLHALAGFQQRALCHALTFPSLQRLVYSMCSLCQEENEDMVPDALQQNP------GAFRL 71
Query: 439 TGVIPTWPRRGWTSEFEEVFPKEEAKELAEGCIRALPKEDGGIGFFAVCFER 490
+P P RG ++ FP AE C+RA PK GFF ER
Sbjct: 72 APALPARPHRGLST-----FPG------AEHCLRASPKTTLSGGFFVAVIER 112
>Hs5453792 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 855
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/230 (23%), Positives = 92/230 (39%), Gaps = 47/230 (20%)
Query: 191 GSIYYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAA 250
G + YD +P I + +Y G ++Q +S P L P + ++D C A
Sbjct: 345 GLVVYDSSVP----------IGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCA 394
Query: 251 PGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTK 310
PG KT+++A ++ I A + + ER K++ + G + H +
Sbjct: 395 PGGKTSYMA-------QLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISH---YDG 444
Query: 311 LGKPELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSV-EPVEQEKEL 369
P++ ++D CSG+G+ +SK + T++D+ + +KEL
Sbjct: 445 RQFPKVVGGFDRVLLDAPCSGTGV----------ISKDPAVKTNKDEKDILRCAHLQKEL 494
Query: 370 FEKEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVV 419
D N +K + + Y TCSI EENE VV
Sbjct: 495 LLSAIDSVNATSKTGGY----------------LVYCTCSITVEENEWVV 528
>Hs20556018 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 812
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/230 (23%), Positives = 92/230 (39%), Gaps = 47/230 (20%)
Query: 191 GSIYYDEYIPNLFGIHPGDKITSHEQYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAA 250
G + YD +P I + +Y G ++Q +S P L P + ++D C A
Sbjct: 345 GLVVYDSSVP----------IGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCA 394
Query: 251 PGNKTTHVAAHIFGDVDTKVDSVKIHAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTK 310
PG KT+++A ++ I A + + ER K++ + G + H +
Sbjct: 395 PGGKTSYMA-------QLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISH---YDG 444
Query: 311 LGKPELFQNVTGFIVDPSCSGSGIFGRKAIDKVNLSKTGSSNTDEDQTSV-EPVEQEKEL 369
P++ ++D CSG+G+ +SK + T++D+ + +KEL
Sbjct: 445 RQFPKVVGGFDRVLLDAPCSGTGV----------ISKDPAVKTNKDEKDILRCAHLQKEL 494
Query: 370 FEKEQDLKNRLAKLSSFQYQIVKHAMSFPSAKKICYSTCSIHAEENERVV 419
D N +K + + Y TCSI EENE VV
Sbjct: 495 LLSAIDSVNATSKTGGY----------------LVYCTCSITVEENEWVV 528
>ECU01g1080 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 370
Score = 55.5 bits (132), Expect = 2e-07
Identities = 64/269 (23%), Positives = 106/269 (38%), Gaps = 56/269 (20%)
Query: 156 IRINPILVKERYDDVLAELNKKFPQRVNSWKQIVPGSIYYDEYIPNLFGIHPGDKITSHE 215
IRIN +L K R D + + SW G + + +P I +
Sbjct: 100 IRINTLL-KGRKDVLKLLSGRGVDLDALSWTD--SGCVVFKSSVP----------IGATP 146
Query: 216 QYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKI 275
+Y G +Q AS P ++ V+D CAAPG KTTH+AA ++ I
Sbjct: 147 EYLAGYYCLQGAASMLPVLNMDLKEGLTVVDLCAAPGGKTTHIAA-------LMENTGVI 199
Query: 276 HAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIF 335
+A + + ER L+ + G + +++ G+ V ++D CSG+G+
Sbjct: 200 YANDVNEERIAGLKSNIQRMGVRNCIVMNMD-----GRKVNVGRVDRVLLDAPCSGTGV- 253
Query: 336 GRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAM 395
+SK S T ++ ++ ++ + Q +++ H
Sbjct: 254 ---------ISKDPSVKTSRTRSEID--------------------RMVTLQKELILHGF 284
Query: 396 SFPSAKKI-CYSTCSIHAEENERVVIDLL 423
I YSTCS+ +ENE VV LL
Sbjct: 285 GMLKPGGILMYSTCSVLVKENEEVVNYLL 313
>7303448 [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 857
Score = 54.7 bits (130), Expect = 3e-07
Identities = 56/223 (25%), Positives = 93/223 (41%), Gaps = 53/223 (23%)
Query: 216 QYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKI 275
+Y G +IQ +S P L P + ++D C+APG K +H+A+ ++ +
Sbjct: 377 EYLAGHYMIQGASSLLPVMALAPQENERILDMCSAPGGKGSHIAS-------IMKNTGVL 429
Query: 276 HAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLGKPELFQNV-TGF---IVDPSCSG 331
A + + +R K + G V + D TK F+N+ TGF ++D C+G
Sbjct: 430 FANDSNRDRIKAIVANFHRLGIVNAV-VSCEDGTK------FRNIMTGFDRVLLDAPCTG 482
Query: 332 SGIFGRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIV 391
+G+ +SK S T + + V+ + + Q +++
Sbjct: 483 TGV----------VSKDPSVKTTKSEVDVQ--------------------RCYNLQRKLL 512
Query: 392 KHAMSFPSAKK-----ICYSTCSIHAEENERVVIDLLLDSKVK 429
A+ AK I YSTCS+ EENE V+ L VK
Sbjct: 513 LTAIDCTDAKSSTGGYIVYSTCSVLPEENEWVIDYALKKRNVK 555
>SPBP8B7.20c [A] KOG1122 tRNA and rRNA cytosine-C5-methylase (nucleolar protein
NOL1/NOP2)
Length = 608
Score = 53.5 bits (127), Expect = 7e-07
Identities = 54/204 (26%), Positives = 82/204 (39%), Gaps = 34/204 (16%)
Query: 216 QYKRGKIIIQDRASCFPAHILNPNSTDVVIDACAAPGNKTTHVAAHIFGDVDTKVDSVKI 275
+Y G I+Q +S P L P + ++D +APG K T+VAA + ++ I
Sbjct: 315 EYLAGHYILQAASSFLPVMALAPQPNERILDMSSAPGGKVTYVAA-------LQKNTGII 367
Query: 276 HAFEKDPERAKTLQMMVATAGCAKGVKIHVGDFTKLGKPELFQNVTGFIVDPSCSGSGIF 335
A + + R K L + G + + D K E+ ++D CSG+G+
Sbjct: 368 FANDSNKARTKALSANIHRLGVRNAIVCNY-DGRKFPN-EVIGGFDRVLLDAPCSGTGV- 424
Query: 336 GRKAIDKVNLSKTGSSNTDEDQTSVEPVEQEKELFEKEQDLKNRLAKLSSFQYQIVKHAM 395
I K KT S D D S +++L D N +K F
Sbjct: 425 ----IYKDQSVKTNKSERDFDTLS----HLQRQLLLSAIDSVNADSKTGGF--------- 467
Query: 396 SFPSAKKICYSTCSIHAEENERVV 419
I YSTCSI +E+E V+
Sbjct: 468 -------IVYSTCSITVDEDEAVI 484
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,878,418
Number of Sequences: 60738
Number of extensions: 1305378
Number of successful extensions: 4121
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 4058
Number of HSP's gapped (non-prelim): 26
length of query: 491
length of database: 30,389,216
effective HSP length: 110
effective length of query: 381
effective length of database: 23,708,036
effective search space: 9032761716
effective search space used: 9032761716
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)