ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2167 check: MH T KOG1989 Signal transduction mechanisms ARK protein kinase family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2167 758538 756208 -777
(777 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL095w [T] KOG1989 ARK protein kinase family 555 e-158
YNL020c [T] KOG1989 ARK protein kinase family 454 e-127
SPBC6B1.02 [T] KOG1989 ARK protein kinase family 307 5e-83
SPBC557.04 [T] KOG1989 ARK protein kinase family 303 5e-82
SPCP1E11.02 [T] KOG1989 ARK protein kinase family 280 8e-75
YBR059c [T] KOG1989 ARK protein kinase family 276 9e-74
Hs7662462 [T] KOG1989 ARK protein kinase family 212 2e-54
Hs9055206 [T] KOG1989 ARK protein kinase family 205 2e-52
7298508 [T] KOG1989 ARK protein kinase family 194 3e-49
At2g32850 [T] KOG1989 ARK protein kinase family 172 2e-42
Hs4885251_1 [T] KOG1989 ARK protein kinase family 165 2e-40
CE00972 [T] KOG1989 ARK protein kinase family 164 6e-40
CE00971 [T] KOG1989 ARK protein kinase family 164 6e-40
7296894_1 [T] KOG1989 ARK protein kinase family 160 7e-39
7298833 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 110 8e-24
CE04586 [T] KOG1989 ARK protein kinase family 103 1e-21
At5g08160 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta... 100 7e-21
YPL236c [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 99 2e-20
Hs17445015 [KIT] KOG2345 Serine/threonine protein kinase/TGF-bet... 92 4e-18
SPAC3H1.13 [KIT] KOG2345 Serine/threonine protein kinase/TGF-bet... 91 5e-18
Hs4505837 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta... 89 3e-17
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 88 6e-17
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 87 7e-17
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 87 1e-16
7290150 [T] KOG0583 Serine/threonine protein kinase 87 1e-16
CE23001 [R] KOG0589 Serine/threonine protein kinase 86 2e-16
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 85 5e-16
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 84 6e-16
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 84 1e-15
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 83 2e-15
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 83 2e-15
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 83 2e-15
YPL150w [T] KOG0583 Serine/threonine protein kinase 82 2e-15
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 81 5e-15
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 81 7e-15
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 81 7e-15
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 81 7e-15
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 80 2e-14
CE03103 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta s... 80 2e-14
YDR122w [T] KOG0583 Serine/threonine protein kinase 79 2e-14
At3g29160 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
At2g45490 [D] KOG0580 Serine/threonine protein kinase 79 2e-14
7302570 [R] KOG0586 Serine/threonine protein kinase 79 3e-14
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 79 3e-14
At3g01090 [T] KOG0583 Serine/threonine protein kinase 79 3e-14
At1g73660 [T] KOG0192 Tyrosine kinase specific for activated (GT... 79 3e-14
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 78 5e-14
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 78 6e-14
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 77 1e-13
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 77 1e-13
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 77 1e-13
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
At1g54510 [R] KOG0589 Serine/threonine protein kinase 77 1e-13
7297080 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
7290147 [T] KOG0583 Serine/threonine protein kinase 77 1e-13
YKL101w [D] KOG0588 Serine/threonine protein kinase 77 1e-13
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 1e-13
7299437 [R] KOG0586 Serine/threonine protein kinase 77 1e-13
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 2e-13
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 76 2e-13
YLR096w [T] KOG0583 Serine/threonine protein kinase 75 3e-13
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
At1g18160 [T] KOG0192 Tyrosine kinase specific for activated (GT... 75 3e-13
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 75 4e-13
CE28643 [T] KOG0583 Serine/threonine protein kinase 75 4e-13
CE27768 [R] KOG0586 Serine/threonine protein kinase 75 4e-13
CE23838 [R] KOG0586 Serine/threonine protein kinase 75 4e-13
CE07458 [T] KOG0583 Serine/threonine protein kinase 75 4e-13
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 75 4e-13
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 75 4e-13
At3g04810 [R] KOG0589 Serine/threonine protein kinase 75 4e-13
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 75 5e-13
CE00847 [T] KOG0583 Serine/threonine protein kinase 75 5e-13
At5g28290 [R] KOG0589 Serine/threonine protein kinase 75 5e-13
At4g33950 [T] KOG0583 Serine/threonine protein kinase 75 5e-13
At3g23000 [T] KOG0583 Serine/threonine protein kinase 75 5e-13
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 5e-13
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 5e-13
YDR523c [T] KOG0201 Serine/threonine protein kinase 74 7e-13
CE24761 [D] KOG0580 Serine/threonine protein kinase 74 7e-13
CE17284 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
At5g39440 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
At1g78290 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 74 7e-13
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 7e-13
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 74 7e-13
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 74 9e-13
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 74 9e-13
At4g40010 [T] KOG0583 Serine/threonine protein kinase 74 9e-13
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 74 9e-13
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 74 9e-13
CE28218 [D] KOG0588 Serine/threonine protein kinase 74 1e-12
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 74 1e-12
YPL209c [D] KOG0580 Serine/threonine protein kinase 73 1e-12
YCL024w [T] KOG0583 Serine/threonine protein kinase 73 1e-12
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
7302464 [R] KOG0586 Serine/threonine protein kinase 73 1e-12
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 73 1e-12
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 73 2e-12
CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 73 2e-12
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 2e-12
At2g23030 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 2e-12
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 2e-12
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 2e-12
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 72 2e-12
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 72 2e-12
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 72 2e-12
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 72 2e-12
At1g10940 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 72 2e-12
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 72 3e-12
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 72 3e-12
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
CE15235 [R] KOG0589 Serine/threonine protein kinase 72 3e-12
At5g25110 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
7301213 [R] KOG0589 Serine/threonine protein kinase 72 3e-12
YDR507c [D] KOG0588 Serine/threonine protein kinase 72 4e-12
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 72 4e-12
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 72 4e-12
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 72 4e-12
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 72 4e-12
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 72 4e-12
At5g20930 [T] KOG1151 Tousled-like protein kinase 72 4e-12
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 4e-12
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 4e-12
At1g30270 [T] KOG0583 Serine/threonine protein kinase 72 4e-12
7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 72 4e-12
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 71 6e-12
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 71 6e-12
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 71 6e-12
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 71 6e-12
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 71 7e-12
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 7e-12
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 71 7e-12
At1g60940 [T] KOG0583 Serine/threonine protein kinase 71 7e-12
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 70 9e-12
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 70 9e-12
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 70 9e-12
CE16081 [T] KOG0583 Serine/threonine protein kinase 70 9e-12
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 1e-11
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 70 1e-11
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 70 1e-11
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 70 1e-11
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 70 2e-11
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 2e-11
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
At5g66880 [T] KOG0583 Serine/threonine protein kinase 70 2e-11
At5g08590 [T] KOG0583 Serine/threonine protein kinase 70 2e-11
At3g20860 [R] KOG0589 Serine/threonine protein kinase 70 2e-11
7299438 [R] KOG0586 Serine/threonine protein kinase 70 2e-11
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 69 2e-11
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 69 2e-11
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 69 2e-11
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 69 2e-11
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 69 2e-11
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 69 2e-11
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 69 2e-11
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 69 2e-11
At2g25880 [D] KOG0580 Serine/threonine protein kinase 69 2e-11
7300224 [T] KOG0201 Serine/threonine protein kinase 69 2e-11
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 69 3e-11
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 69 3e-11
At2g42550 [T] KOG0198 MEKK and related serine/threonine protein ... 69 3e-11
7303111 [T] KOG0695 Serine/threonine protein kinase 69 3e-11
YPR054w [T] KOG0660 Mitogen-activated protein kinase 69 4e-11
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 69 4e-11
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 69 4e-11
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 69 4e-11
CE28479 [T] KOG0583 Serine/threonine protein kinase 69 4e-11
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 4e-11
At3g15220 [T] KOG0201 Serine/threonine protein kinase 69 4e-11
At1g01140 [T] KOG0583 Serine/threonine protein kinase 69 4e-11
7300915 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 69 4e-11
YPL141c [T] KOG0583 Serine/threonine protein kinase 68 5e-11
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 68 5e-11
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 68 5e-11
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 68 5e-11
Hs4504357 [T] KOG0197 Tyrosine kinases 68 5e-11
Hs13653487 [T] KOG0197 Tyrosine kinases 68 5e-11
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 5e-11
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 68 5e-11
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 5e-11
At2g34180 [T] KOG0583 Serine/threonine protein kinase 68 5e-11
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 5e-11
YHR102w [T] KOG0201 Serine/threonine protein kinase 68 6e-11
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 68 6e-11
Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 6e-11
Hs21735566 [T] KOG0192 Tyrosine kinase specific for activated (G... 68 6e-11
Hs21735564 [T] KOG0192 Tyrosine kinase specific for activated (G... 68 6e-11
Hs21735562 [T] KOG0192 Tyrosine kinase specific for activated (G... 68 6e-11
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 68 6e-11
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 68 6e-11
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 68 6e-11
At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GT... 68 6e-11
At1g53165 [T] KOG0201 Serine/threonine protein kinase 68 6e-11
7293601 [T] KOG0577 Serine/threonine protein kinase 68 6e-11
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 67 8e-11
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 67 8e-11
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 67 8e-11
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 8e-11
At5g10930 [T] KOG0583 Serine/threonine protein kinase 67 8e-11
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 67 8e-11
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 67 8e-11
7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 67 8e-11
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 67 1e-10
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 67 1e-10
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 67 1e-10
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 67 1e-10
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 67 1e-10
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 67 1e-10
At3g50500 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 67 1e-10
7290249 [R] KOG0586 Serine/threonine protein kinase 67 1e-10
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 67 1e-10
Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 67 1e-10
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 67 1e-10
ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and ty... 67 1e-10
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 67 1e-10
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 67 1e-10
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 67 1e-10
At4g32830 [D] KOG0580 Serine/threonine protein kinase 67 1e-10
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 67 1e-10
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 67 1e-10
7299793 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 66 2e-10
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 66 2e-10
CE04904 [T] KOG0194 Protein tyrosine kinase 66 2e-10
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 66 2e-10
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 66 2e-10
Hs4503787 [T] KOG0197 Tyrosine kinases 66 2e-10
CE17354 [T] KOG0694 Serine/threonine protein kinase 66 2e-10
CE17353 [T] KOG0694 Serine/threonine protein kinase 66 2e-10
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 66 2e-10
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 66 2e-10
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 66 2e-10
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 66 2e-10
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 65 3e-10
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 65 3e-10
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 65 3e-10
At5g58380 [T] KOG0583 Serine/threonine protein kinase 65 3e-10
At5g45820 [T] KOG0583 Serine/threonine protein kinase 65 3e-10
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 65 3e-10
SPCC18B5.03 [D] KOG0601 Cyclin-dependent kinase WEE1 65 4e-10
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 65 4e-10
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 65 4e-10
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 65 4e-10
CE21025 [D] KOG0580 Serine/threonine protein kinase 65 4e-10
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
At2g25090 [T] KOG0583 Serine/threonine protein kinase 65 4e-10
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 65 4e-10
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 65 4e-10
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 65 5e-10
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 65 5e-10
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 65 5e-10
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 65 5e-10
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 65 5e-10
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 65 5e-10
Hs4505055 [T] KOG0197 Tyrosine kinases 65 5e-10
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 65 5e-10
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 65 5e-10
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 65 5e-10
7296128 [T] KOG0583 Serine/threonine protein kinase 65 5e-10
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 64 7e-10
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 64 7e-10
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 64 7e-10
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 64 7e-10
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 64 7e-10
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 64 7e-10
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 64 7e-10
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 7e-10
Hs7706601 [T] KOG0192 Tyrosine kinase specific for activated (GT... 64 9e-10
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 64 9e-10
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 9e-10
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 64 9e-10
Hs19526767 [T] KOG0192 Tyrosine kinase specific for activated (G... 64 9e-10
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 9e-10
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 64 9e-10
At5g63650 [T] KOG0583 Serine/threonine protein kinase 64 9e-10
7294217 [D] KOG0588 Serine/threonine protein kinase 64 9e-10
7292519 [T] KOG0197 Tyrosine kinases 64 9e-10
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 64 1e-09
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 64 1e-09
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 64 1e-09
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 64 1e-09
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 1e-09
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 64 1e-09
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 64 1e-09
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 1e-09
At4g18700 [T] KOG0583 Serine/threonine protein kinase 64 1e-09
At4g14580 [T] KOG0583 Serine/threonine protein kinase 64 1e-09
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 64 1e-09
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 64 1e-09
7297776 [D] KOG0580 Serine/threonine protein kinase 64 1e-09
YOR233w [T] KOG0583 Serine/threonine protein kinase 63 2e-09
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 63 2e-09
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 63 2e-09
CE28674 [T] KOG0201 Serine/threonine protein kinase 63 2e-09
CE07510 [T] KOG0201 Serine/threonine protein kinase 63 2e-09
At3g58640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 2e-09
7299536 [D] KOG0580 Serine/threonine protein kinase 63 2e-09
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 63 2e-09
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 63 2e-09
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 63 2e-09
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 63 2e-09
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 63 2e-09
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 63 2e-09
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 63 2e-09
CE23702 [T] KOG4721 Serine/threonine protein kinase contains leu... 63 2e-09
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 63 2e-09
CE02586 [T] KOG0696 Serine/threonine protein kinase 63 2e-09
At4g24480 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 2e-09
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 2e-09
At1g08720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 2e-09
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 63 2e-09
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 63 2e-09
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 63 2e-09
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 63 2e-09
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 62 3e-09
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 62 3e-09
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 62 3e-09
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 62 3e-09
At5g49470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 3e-09
At5g35410 [T] KOG0583 Serine/threonine protein kinase 62 3e-09
At3g44200 [R] KOG0589 Serine/threonine protein kinase 62 3e-09
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 3e-09
At2g30360 [T] KOG0583 Serine/threonine protein kinase 62 3e-09
7300106 [T] KOG0690 Serine/threonine protein kinase 62 3e-09
7290436 [T] KOG1151 Tousled-like protein kinase 62 3e-09
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 62 3e-09
YBL105c [T] KOG0694 Serine/threonine protein kinase 62 3e-09
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 62 3e-09
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 62 3e-09
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 62 3e-09
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 62 3e-09
Hs11140819 [T] KOG1151 Tousled-like protein kinase 62 3e-09
CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 62 3e-09
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 62 3e-09
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 62 3e-09
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
At1g48260 [T] KOG0583 Serine/threonine protein kinase 62 3e-09
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 62 3e-09
SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2 62 4e-09
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 62 4e-09
Hs4557681 [T] KOG0197 Tyrosine kinases 62 4e-09
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 62 4e-09
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 62 4e-09
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 62 4e-09
Hs20428652 [T] KOG0197 Tyrosine kinases 62 4e-09
At5g11850 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 4e-09
At5g07070 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 4e-09
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 4e-09
At4g24400 [T] KOG0583 Serine/threonine protein kinase 62 4e-09
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 62 4e-09
7302860 [T] KOG0696 Serine/threonine protein kinase 62 4e-09
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 61 6e-09
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 61 6e-09
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 61 6e-09
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 61 6e-09
Hs4885609 [T] KOG0197 Tyrosine kinases 61 6e-09
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 61 6e-09
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 6e-09
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 61 6e-09
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 61 6e-09
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 61 6e-09
CE06503 [T] KOG0194 Protein tyrosine kinase 61 6e-09
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 61 6e-09
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 61 6e-09
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 61 6e-09
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 61 7e-09
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 61 7e-09
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 61 7e-09
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 61 7e-09
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 61 7e-09
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 61 7e-09
At3g17510 [T] KOG0583 Serine/threonine protein kinase 61 7e-09
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 61 7e-09
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 7e-09
At1g29230 [T] KOG0583 Serine/threonine protein kinase 61 7e-09
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 60 1e-08
Hs5174647 [T] KOG0197 Tyrosine kinases 60 1e-08
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 60 1e-08
Hs20553830 [J] KOG1035 eIF-2alpha kinase GCN2 60 1e-08
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 60 1e-08
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 60 1e-08
CE27410 [T] KOG0583 Serine/threonine protein kinase 60 1e-08
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 60 1e-08
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 60 1e-08
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
At4g00330 [T] KOG1187 Serine/threonine protein kinase 60 1e-08
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 60 1e-08
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 60 1e-08
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 60 1e-08
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 60 1e-08
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 60 1e-08
Hs4507917 [D] KOG0601 Cyclin-dependent kinase WEE1 60 1e-08
Hs4506401 [T] KOG0193 Serine/threonine protein kinase RAF 60 1e-08
Hs4502413 [T] KOG0197 Tyrosine kinases 60 1e-08
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 60 1e-08
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 60 1e-08
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 60 1e-08
Hs13112052 [T] KOG0200 Fibroblast/platelet-derived growth factor... 60 1e-08
Hs13112050 [T] KOG0200 Fibroblast/platelet-derived growth factor... 60 1e-08
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 60 1e-08
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 60 1e-08
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 60 1e-08
7300559 [T] KOG4279 Serine/threonine protein kinase 60 1e-08
7294770 [T] KOG0603 Ribosomal protein S6 kinase 60 1e-08
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 60 1e-08
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 60 2e-08
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 60 2e-08
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 60 2e-08
Hs13186265 [T] KOG0200 Fibroblast/platelet-derived growth factor... 60 2e-08
CE26710 [T] KOG0198 MEKK and related serine/threonine protein ki... 60 2e-08
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 60 2e-08
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 60 2e-08
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 2e-08
At3g22750 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 2e-08
At3g06640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 2e-08
7303211 [T] KOG4717 Serine/threonine protein kinase 60 2e-08
7302861 [T] KOG0696 Serine/threonine protein kinase 60 2e-08
YDR477w [T] KOG0583 Serine/threonine protein kinase 59 2e-08
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 59 2e-08
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 59 2e-08
Hs4503709 [T] KOG0200 Fibroblast/platelet-derived growth factor ... 59 2e-08
Hs18677726 [T] KOG1151 Tousled-like protein kinase 59 2e-08
Hs13186269 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
Hs13186263 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
Hs13186261 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
Hs13186259 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
Hs13186255 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
Hs13186253 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
Hs13186243 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 2e-08
CE29092 [T] KOG0694 Serine/threonine protein kinase 59 2e-08
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 59 2e-08
CE09248 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 59 2e-08
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 59 2e-08
At5g57630 [T] KOG0583 Serine/threonine protein kinase 59 2e-08
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 2e-08
7300413 [T] KOG0583 Serine/threonine protein kinase 59 2e-08
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 59 2e-08
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 59 3e-08
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 59 3e-08
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 59 3e-08
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 59 3e-08
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 59 3e-08
Hs4757868 [T] KOG0193 Serine/threonine protein kinase RAF 59 3e-08
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 59 3e-08
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 59 3e-08
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 59 3e-08
Hs13186273 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 3e-08
Hs13186271 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 3e-08
Hs13186251 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 3e-08
Hs13186236 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 3e-08
Hs13186234 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 3e-08
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 59 3e-08
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 59 3e-08
Hs11276087 [T] KOG0200 Fibroblast/platelet-derived growth factor... 59 3e-08
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 3e-08
At5g11015 [T] KOG1187 Serine/threonine protein kinase 59 3e-08
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 3e-08
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 59 3e-08
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 3e-08
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 59 3e-08
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 59 3e-08
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 59 3e-08
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 59 4e-08
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 59 4e-08
Hs22045264 [T] KOG0583 Serine/threonine protein kinase 59 4e-08
Hs21735544 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 59 4e-08
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 59 4e-08
CE29298 [T] KOG0690 Serine/threonine protein kinase 59 4e-08
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 59 4e-08
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 59 4e-08
CE18646 [T] KOG0690 Serine/threonine protein kinase 59 4e-08
CE03609 [T] KOG0194 Protein tyrosine kinase 59 4e-08
At5g58940 [T] KOG1187 Serine/threonine protein kinase 59 4e-08
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 59 4e-08
At2g42630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 4e-08
>YIL095w [T] KOG1989 ARK protein kinase family
Length = 810
Score = 555 bits (1431), Expect = e-158
Identities = 343/761 (45%), Positives = 437/761 (57%), Gaps = 93/761 (12%)
Query: 1 MNQPQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVV 60
MN PQI Y GTIL VGSH K++KYL SGGFA VY+ EISPPDP N+ACLKRV+V
Sbjct: 1 MNTPQISLYEPGTILTVGSHHAKIIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRVIV 60
Query: 61 PDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDF 120
P K LNTLRAEVD+MK LR NK +VSYIDSHA +S VN YEV++LME+C GGLIDF
Sbjct: 61 PHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARS-VNGIAYEVFVLMEFCERGGLIDF 119
Query: 121 MNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGS 180
MNTRLQNRLQE EIL IMSQ QG+ AMHALQPPLIHRDIKIENVL+S + +K+CDFGS
Sbjct: 120 MNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGS 179
Query: 181 VSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTC 240
VSGVIR PRNT+EFNYVQ+DI+ NTTAQYR PEMIDLYRGLPIDEKSDIWALGVFLYK C
Sbjct: 180 VSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKIC 239
Query: 241 YYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQ 300
YYTTPFEK+GE+ IL +++++P++P+YSDR+KNLI +ML P +RPNICQV+EEVSR+Q
Sbjct: 240 YYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQ 299
Query: 301 GIPCPIKNFYLLRMMDKQEQPRVSPPP----HVPQMXXXXXXXXXXXXQHLPPQVVSNVQ 356
PCPI+NFYLLR M++ +++ P +VP Q PP ++ V
Sbjct: 300 NKPCPIRNFYLLRAMNQNANTQLAGEPSSTTYVPTQKFIPVQSLQSINQ--PPNMMP-VT 356
Query: 357 TPSKTASIQHLPYLHVSKSQPMVTQQDLLSQKQPAGKTVP-QTVSNYTSSDPFSKIDRSA 415
S T ++ P ++ VT L + T P + SD F+ +
Sbjct: 357 HVSTTPNLGTFPISINDNNKTEVTAHAGLQVGSHSNLTSPLMKTKSVPLSDEFASLYYKE 416
Query: 416 L--LSTSATMESLPRAMRIPQLEYQQPHLLTXXXXXXXXXXXXXXXNGRGAISSILASNR 473
L S T +S+ + + PQ + P LT +++ +
Sbjct: 417 LHPFQKSQTFKSV-ESFQSPQRKSMPPLSLT-------------------PVNNDIFDRV 456
Query: 474 TSLDRP-KYVDSETQTSDHPSELGXXXXXXXXXXXXXXXXXXXXXXXXXGGSLTRKIGSK 532
++++RP YVDSETQT D+ + G + R + SK
Sbjct: 457 SAINRPNNYVDSETQTIDNMAVPNLKLSPTITSKSLSSTKEIAAPDNINGSKIVRSLSSK 516
Query: 533 MKKVITGEKRGFSTIRSAQNTGESVKSAFNALRKGISSMQFTGDS--SSRKSSLE----- 585
+KKVITGE RG S I+S QNTG+S++SAF LR G FTG+S +SR +S +
Sbjct: 517 LKKVITGESRGNSPIKSRQNTGDSIRSAFGKLRHG-----FTGNSVNNSRSASFDNNNVN 571
Query: 586 ------ARKYRSTSGKSIP---------ENTSSNTKSHRRST------SSFSFVPENND- 623
R+ S+S S P E + N + +R + S F NN
Sbjct: 572 GNGNNTNRRLVSSSTSSFPKFNSDTKRKEESDKNQRLEKRRSMPPSILSDFDQHERNNSR 631
Query: 624 ------YELIEDIQKEKPXXXXXX-----------XXXXXXXXXIQKRVKDLINADDIP- 665
Y ++K + IQ+RV +L+ + D P
Sbjct: 632 TGSRDYYRSHSPVKKTQASAKTTSKPTLIPDNGNVNINQEKKESIQRRVHNLLKSSDDPV 691
Query: 666 NRSSATGYGKYTDIGRKTDISDHHKSNANRKSSTVITPVHE 706
SA+GYGKYTDIG +T +NR SS ITP+ E
Sbjct: 692 TYKSASGYGKYTDIGTET---------SNRHSSVRITPITE 723
>YNL020c [T] KOG1989 ARK protein kinase family
Length = 638
Score = 454 bits (1167), Expect = e-127
Identities = 216/313 (69%), Positives = 261/313 (83%)
Query: 1 MNQPQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVV 60
MNQPQI Y GT L VGSHQV+++KYL SGGFA VYS I+PPDP +VACLKRV+V
Sbjct: 1 MNQPQIGTYNVGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIV 60
Query: 61 PDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDF 120
PDK SLNTLRAEVD+M+ L+ N+++VSYIDSHA K+ ++ G YEV++LMEYC GGLIDF
Sbjct: 61 PDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDF 120
Query: 121 MNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGS 180
MNTRLQNRL EFEIL IMSQV+QGVAAMHALQPPLIHRDIKIENVL+S N+E+KLCDFGS
Sbjct: 121 MNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGS 180
Query: 181 VSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTC 240
V G+IR PRN++E +YVQ DI+KNTTAQYR PEMID +RGLPIDEKSDIWALG+FLYK C
Sbjct: 181 VCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLC 240
Query: 241 YYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQ 300
YYTTPFEK G+ AIL+ KFEFP YP YS+++K LI +L DP RPN+ Q+++ +S +Q
Sbjct: 241 YYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQ 300
Query: 301 GIPCPIKNFYLLR 313
+PCPI + +++
Sbjct: 301 NVPCPINDIQVVQ 313
>SPBC6B1.02 [T] KOG1989 ARK protein kinase family
Length = 953
Score = 307 bits (786), Expect = 5e-83
Identities = 182/422 (43%), Positives = 239/422 (56%), Gaps = 20/422 (4%)
Query: 8 KYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLN 67
K +GT + VGSH V + +YL+ GGF+HVY + P LKR+ VPDK +L
Sbjct: 43 KIPAGTKIQVGSHSVIIQRYLSEGGFSHVYLALLENEKPFV------LKRIYVPDKTALQ 96
Query: 68 TLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQN 127
+ E+++MK L+G++ IV+YIDS A S + YEVYLLME+C+GGGLIDFMNTRLQ+
Sbjct: 97 LVHGEIETMKRLKGHRHIVNYIDSSALYSK-SENRYEVYLLMEFCAGGGLIDFMNTRLQH 155
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
RL E EIL I++ V VAAMH L PPLIHRD+KIENVLL + +KLCDFGS +
Sbjct: 156 RLTEGEILKILADVCDAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAP 215
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFE 247
+ +++ +I TT QYR PEMID+ R IDEKSDIWA+GV YK CYYTTPFE
Sbjct: 216 ATTPDTIMFLEQNIAAYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFE 275
Query: 248 KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIK 307
+ G SAIL + F FP +PRYSDR+K I+ L+ P RPNI Q ++E+ +QG P +
Sbjct: 276 QVGNSAILKASFSFPPFPRYSDRMKRFIATCLQEQPSHRPNIYQTLKEIMEMQGTPLKLP 335
Query: 308 NFYLLRMMDKQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQVVSNVQTPSKTASIQHL 367
+ Y PR +P P LPP + VQT S +
Sbjct: 336 DVYGGVNASTYNPPR-APLQRTPS-GSLTPLSSRPAHTSLPP--IPTVQTTSSNVPPVNR 391
Query: 368 PYLHVSKSQPMVTQQDLLSQKQPAGKTVPQTVSNYTSSDPFSKIDRSALLSTSATMESLP 427
P L KS+ L +Q P ++ P A S SAT+++ P
Sbjct: 392 PSL---KSKSPSVSNILSNQLSPISSANNDVMARLQPKSPI-----PATKSYSATIQT-P 442
Query: 428 RA 429
R+
Sbjct: 443 RS 444
>SPBC557.04 [T] KOG1989 ARK protein kinase family
Length = 872
Score = 303 bits (777), Expect = 5e-82
Identities = 156/307 (50%), Positives = 211/307 (67%), Gaps = 6/307 (1%)
Query: 7 EKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASL 66
EK +G+ +G + V + KY+A GGF+HVY V+ + P A LKR+ PD+ +L
Sbjct: 10 EKLLAGSKFVIGKYNVTIEKYIAEGGFSHVYLVQTNSKTDGSPIT-AVLKRMYSPDENAL 68
Query: 67 NTLRAEVDSMKALRGNKFIVSYIDS---HATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
++ E+++M+ L+ N +VSYIDS K+ VN G +E+ LLMEYC+GGGLIDFMN
Sbjct: 69 RFVKTEIETMELLKSNPHVVSYIDSCIFPLEKAGVNTG-FEILLLMEYCAGGGLIDFMNQ 127
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
RLQ RL E E+L I+S + QGVA++H L+PPLIHRD+K+ENVLLS N FKLCDFGSV+
Sbjct: 128 RLQTRLSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVENVLLSFN-TFKLCDFGSVTE 186
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYT 243
+ A N+ E ++ I TT QYR PEMI+LY GL IDEKSD+WALGV LYK CYYT
Sbjct: 187 PMHAAENSSEIQALEKSINTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYT 246
Query: 244 TPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
TPFE G +AIL + + FP +P YS +KN+I +L+ +P RPNI Q++ E+ R++G
Sbjct: 247 TPFETQGPNAILTASYSFPPFPPYSHSLKNVIIALLQPNPCLRPNIFQLMCEICRLRGTA 306
Query: 304 CPIKNFY 310
P ++ Y
Sbjct: 307 LPFRDIY 313
>SPCP1E11.02 [T] KOG1989 ARK protein kinase family
Length = 650
Score = 280 bits (715), Expect = 8e-75
Identities = 150/303 (49%), Positives = 194/303 (63%), Gaps = 10/303 (3%)
Query: 14 ILPVG------SHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLN 67
+LPVG V V +YLA GGF+HVY V++ P P A LKR+ D +L
Sbjct: 19 LLPVGFSCTVEKFSVTVKRYLAEGGFSHVYLVQLVFPGK--PPFEAVLKRIFATDAMALR 76
Query: 68 TLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQN 127
+ EV +MK + K VSY S ++ N +EV +L+EYC GGLIDF+NTRLQ
Sbjct: 77 AVHEEVRTMKLVSNQKRCVSYYGSEFFRTSKN--QFEVLVLLEYCPCGGLIDFLNTRLQV 134
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
RL E EIL I S V++ VA MH L+PPLIHRD+KIENVLL+ + +KLCDFGS I
Sbjct: 135 RLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAPNSYKLCDFGSACHPIPG 194
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFE 247
+ E ++YDI K TT QYRCPEMI++++G IDEKSDIWALGV YK CYYTTPFE
Sbjct: 195 AKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVLFYKLCYYTTPFE 254
Query: 248 KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIK 307
G +AI+ + FP +P YSDR+K LIS +L+ P +RPNI Q E+ +++ +P I
Sbjct: 255 HQGLAAIMNVSYAFPTFPPYSDRLKRLISTLLQQYPWQRPNIYQTFCEICKMRNVPIHIY 314
Query: 308 NFY 310
+ Y
Sbjct: 315 DIY 317
>YBR059c [T] KOG1989 ARK protein kinase family
Length = 1108
Score = 276 bits (706), Expect = 9e-74
Identities = 152/319 (47%), Positives = 202/319 (62%), Gaps = 10/319 (3%)
Query: 1 MNQPQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEI---------SPPDPVCPDN 51
M P +E+Y G I+ VG+H+V+V+ YLA GGFA +Y V+ + P+ +
Sbjct: 14 MGHPAVERYTPGHIVCVGTHKVEVVNYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGD 73
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
VACLKRV+V D+ LN +R EV+ MK L+G IV Y DS+A++ V +EV LLME
Sbjct: 74 VACLKRVLVQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMEL 133
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
C L+D+MN RL +L E EI+ IM V+ ++ MH L LIHRDIKIENVL+ +
Sbjct: 134 CPNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKN 193
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWA 231
FKL DFGS S ++ + +I +TT QYR PEMIDLYR LPI+EKSDIWA
Sbjct: 194 NFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWA 253
Query: 232 LGVFLYKTCYYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQ 291
LGVFLYK ++TTPFE G+ AIL SK+EFP +YS ++ NLI +ML +P RPNI Q
Sbjct: 254 LGVFLYKLLFFTTPFEMTGQFAILHSKYEFPV-NKYSSKLINLIIIMLAENPNLRPNIYQ 312
Query: 292 VVEEVSRIQGIPCPIKNFY 310
V+ + I + PI++ Y
Sbjct: 313 VLYHLCEILNVEVPIEDKY 331
>Hs7662462 [T] KOG1989 ARK protein kinase family
Length = 863
Score = 212 bits (540), Expect = 2e-54
Identities = 143/416 (34%), Positives = 204/416 (48%), Gaps = 31/416 (7%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVAC-LKRVVVPDKASLNTLR 70
G + +G QV V + LA GGFA V+ V S + + C LKR+ V ++ L +
Sbjct: 36 GRVFGIGRQQVTVDEVLAEGGFAIVFLVRTS-------NGMKCALKRMFVNNEHDLQVCK 88
Query: 71 AEVDSMKALRGNKFIVSYIDSHATKSPVNVG-MYEVYLLMEYCSGGGLIDFMNTRLQNRL 129
E+ M+ L G+K IV YIDS V+ G ++EV +LM++C GG +++ MN RLQ
Sbjct: 89 REIQIMRDLSGHKNIVGYIDSSINN--VSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGF 146
Query: 130 QEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPR 189
E E+L I + VA +H + P+IHRD+K+EN+LL + LCDFGS + + P+
Sbjct: 147 TENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ 206
Query: 190 NTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKN 249
TE N V+ +I K TT YR PEM++LY G I K+DIWALG LYK CY+T PF ++
Sbjct: 207 -TEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES 265
Query: 250 GESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNF 309
+ AI F P RYS + LI ML DP KRP+I QV ++ CPI N
Sbjct: 266 -QVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNV 324
Query: 310 Y-------------LLRMMDKQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQ----VV 352
K+ QP+ +P P +
Sbjct: 325 QNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPI 384
Query: 353 SNVQTPSKTASIQHLPYLHVSKSQP-MVTQQDLLSQKQPAGKTVPQTVSNYTSSDP 407
TP K A++Q P S +QP ++ + P + +PQT + + P
Sbjct: 385 QPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPP 440
>Hs9055206 [T] KOG1989 ARK protein kinase family
Length = 355
Score = 205 bits (522), Expect = 2e-52
Identities = 119/296 (40%), Positives = 163/296 (54%), Gaps = 12/296 (4%)
Query: 14 ILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVAC-LKRVVVPDKASLNTLRAE 72
+ VG HQV + + LA GGF+ V+ V + C LKR+ V + LN + E
Sbjct: 43 VFAVGRHQVTLEESLAEGGFSTVFLVRTH-------GGIRCALKRMYVNNMPDLNVCKRE 95
Query: 73 VDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEF 132
+ MK L G+K IV Y+D NV +EV +LMEYC G +++ MN +LQ E
Sbjct: 96 ITIMKELSGHKNIVGYLDCAVNSISDNV--WEVLILMEYCRAGQVVNQMNKKLQTGFTEP 153
Query: 133 EILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTE 192
E+L I + VA +H + P+IHRD+K+EN+LL+ + LCDFGS + P+ +
Sbjct: 154 EVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQK-D 212
Query: 193 EFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES 252
N V+ +I K TT YR PEMI+LY G PI K+DIWALG LYK C++T PF ++ +
Sbjct: 213 GVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-QV 271
Query: 253 AILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKN 308
AI F P RYS + LI ML DP RP+I QV + CP+ N
Sbjct: 272 AICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSN 327
>7298508 [T] KOG1989 ARK protein kinase family
Length = 1460
Score = 194 bits (494), Expect = 3e-49
Identities = 122/301 (40%), Positives = 161/301 (52%), Gaps = 10/301 (3%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA 71
G + VG V V LA GGFA V+ + A LKR+ V ++ LN +
Sbjct: 36 GKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATKYA-LKRMYVNNEHDLNVAKR 94
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
E+ L G+K I+ Y+DS T P G+ EV LLM YC ++ MN RL E
Sbjct: 95 EIQIASNLSGHKNIIGYVDSSIT--PTGNGVCEVLLLMPYCKHH-MLAMMNARLHVGFTE 151
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
E+LNI +++ V+ +H Q P+IHRD+K+EN+L + F LCDFGS + P+
Sbjct: 152 PEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQ- 210
Query: 192 EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE 251
VQ +I K TT YR PEMIDLY G I K+DIWALG LYK C+++ PF GE
Sbjct: 211 HGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPF---GE 267
Query: 252 S--AILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNF 309
S AI +F P +YS + LI ML D KRPNI QV E R+ G P++N
Sbjct: 268 STLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNL 327
Query: 310 Y 310
+
Sbjct: 328 H 328
>At2g32850 [T] KOG1989 ARK protein kinase family
Length = 693
Score = 172 bits (436), Expect = 2e-42
Identities = 109/324 (33%), Positives = 163/324 (49%), Gaps = 12/324 (3%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA 71
G L +G+ +V+V +A GGF+ VY + D LK ++ D+ SL +
Sbjct: 17 GRFLEIGNLKVQVRNVIAEGGFSSVYLAQ----DVNHASKQYALKHMICNDEESLELVMK 72
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
E+ +K+L+G+ +V+ + +H + E L M++C G L+D + R +E
Sbjct: 73 EISVLKSLKGHPNVVT-LYAHGILD-MGRNKKEALLAMDFC-GKSLVDVLENRGAGYFEE 129
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
+ L I V V AMH P + HRD+K EN+LLS + ++KLCDFGSVS +
Sbjct: 130 KQALTIFRDVCNAVFAMHCQSPRIAHRDLKAENLLLSSDGQWKLCDFGSVSTNHKIFERA 189
Query: 192 EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE 251
EE + +I K TT YR PEM DL+R I EK DIWALG L++ CY+ F+ +
Sbjct: 190 EEMGIEEDNIRKYTTPTYRAPEMWDLFRREMISEKVDIWALGCLLFRICYFKNAFDGESK 249
Query: 252 SAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV-----SRIQGIPCPI 306
IL + P P+YS + +LI ML+ P +RP+I QV + S+++ +
Sbjct: 250 LQILNGNYRIPESPKYSVFITDLIKEMLQASPDERPDITQVKSQFLLIVSSQLRKCKMSL 309
Query: 307 KNFYLLRMMDKQEQPRVSPPPHVP 330
PR SPPP P
Sbjct: 310 TTCSSKSATKPSPAPRRSPPPPPP 333
>Hs4885251_1 [T] KOG1989 ARK protein kinase family
Length = 395
Score = 165 bits (418), Expect = 2e-40
Identities = 104/294 (35%), Positives = 156/294 (52%), Gaps = 13/294 (4%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA 71
G + +G +++V + LA GGFA VY + V LKR++ ++ +
Sbjct: 30 GQTVELGELRLRVRRVLAEGGFAFVYEAQ-----DVGSGREYALKRLLSNEEEKNRAIIQ 84
Query: 72 EVDSMKALRGNKFIVSYIDSHAT-KSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR-- 128
EV MK L G+ IV + + + K + G E LL E C G L++F+ ++++R
Sbjct: 85 EVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQ-LVEFLK-KMESRGP 142
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L +L I Q + V MH +PP+IHRD+K+EN+LLS KLCDFGS + + P
Sbjct: 143 LSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYP 202
Query: 189 R---NTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
+ + V+ +I +NTT YR PE+IDLY PI EK DIWALG LY C+ P
Sbjct: 203 DYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHP 262
Query: 246 FEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRI 299
FE + I+ K+ P + +LI ML+V+P +R +I +VV ++ I
Sbjct: 263 FEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVHQLQEI 316
>CE00972 [T] KOG1989 ARK protein kinase family
Length = 690
Score = 164 bits (414), Expect = 6e-40
Identities = 124/382 (32%), Positives = 189/382 (49%), Gaps = 38/382 (9%)
Query: 7 EKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPD-KAS 65
E G L + +V + K +A GGFA VY +N LKR D +
Sbjct: 32 ENKCKGVTLKLDHTRVTIEKQIAEGGFAIVYVASDRK------NNKFALKRQFTKDNEKQ 85
Query: 66 LNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRL 125
L E +K G+K IV ++DS+ + + G++E LL EY ++ MN R+
Sbjct: 86 LEACCREHSFLKQCIGHKNIVEFVDSYT--NCLGNGIWECMLLTEYHQKN-VLQLMNERI 142
Query: 126 -QNR-LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS--KNHEFKLCDFGSV 181
QN+ L EIL+I + + + V+ +H P+IHRD+K+ENVL+S K + LCDFGS
Sbjct: 143 SQNQYLTNDEILSIFTDLCEAVSFIHNRPQPIIHRDLKVENVLISSHKPPHYVLCDFGSA 202
Query: 182 SGVIRAPRNTEEFN--YVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
+ I + E++ YV+ ++ +NTT YR PEMID Y GL I KSDIWALGV LY+
Sbjct: 203 TTQILS---VEKYGVEYVKSEVERNTTMCYRSPEMIDFYSGLEIGLKSDIWALGVLLYRL 259
Query: 240 CYYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQ-------- 291
C++ PFE++ AI + ++FP+ P D +K LI ++L +D +RP+I Q
Sbjct: 260 CFFCVPFEES-PLAIQSVNYQFPSVPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEA 318
Query: 292 -----VVEEVSR---IQGIPCPIKNFYLLRMMDKQEQPRVSPPPHVPQMXXXXXXXXXXX 343
+ EE+ +P L+R R S P +
Sbjct: 319 NHRKPLSEEIQNKKCTDAVPSLKSCIQLMRDGSNPRNKRDSSPRNPEAPPIQSSSKMASL 378
Query: 344 XQHLPPQVVSNVQTPSKTASIQ 365
Q +P +SN+ PS + +++
Sbjct: 379 SQQVPS--ISNISMPSGSGTVE 398
>CE00971 [T] KOG1989 ARK protein kinase family
Length = 1077
Score = 164 bits (414), Expect = 6e-40
Identities = 124/382 (32%), Positives = 189/382 (49%), Gaps = 38/382 (9%)
Query: 7 EKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPD-KAS 65
E G L + +V + K +A GGFA VY +N LKR D +
Sbjct: 32 ENKCKGVTLKLDHTRVTIEKQIAEGGFAIVYVASDRK------NNKFALKRQFTKDNEKQ 85
Query: 66 LNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRL 125
L E +K G+K IV ++DS+ + + G++E LL EY ++ MN R+
Sbjct: 86 LEACCREHSFLKQCIGHKNIVEFVDSYT--NCLGNGIWECMLLTEYHQKN-VLQLMNERI 142
Query: 126 -QNR-LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS--KNHEFKLCDFGSV 181
QN+ L EIL+I + + + V+ +H P+IHRD+K+ENVL+S K + LCDFGS
Sbjct: 143 SQNQYLTNDEILSIFTDLCEAVSFIHNRPQPIIHRDLKVENVLISSHKPPHYVLCDFGSA 202
Query: 182 SGVIRAPRNTEEFN--YVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
+ I + E++ YV+ ++ +NTT YR PEMID Y GL I KSDIWALGV LY+
Sbjct: 203 TTQILS---VEKYGVEYVKSEVERNTTMCYRSPEMIDFYSGLEIGLKSDIWALGVLLYRL 259
Query: 240 CYYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQ-------- 291
C++ PFE++ AI + ++FP+ P D +K LI ++L +D +RP+I Q
Sbjct: 260 CFFCVPFEES-PLAIQSVNYQFPSVPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEA 318
Query: 292 -----VVEEVSR---IQGIPCPIKNFYLLRMMDKQEQPRVSPPPHVPQMXXXXXXXXXXX 343
+ EE+ +P L+R R S P +
Sbjct: 319 NHRKPLSEEIQNKKCTDAVPSLKSCIQLMRDGSNPRNKRDSSPRNPEAPPIQSSSKMASL 378
Query: 344 XQHLPPQVVSNVQTPSKTASIQ 365
Q +P +SN+ PS + +++
Sbjct: 379 SQQVPS--ISNISMPSGSGTVE 398
>7296894_1 [T] KOG1989 ARK protein kinase family
Length = 391
Score = 160 bits (405), Expect = 7e-39
Identities = 104/324 (32%), Positives = 166/324 (51%), Gaps = 19/324 (5%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA 71
G ++ V H++++ +A GG+A VY + V LKR++ D + +
Sbjct: 40 GQVVEVAGHRLRIKCVIAEGGYAFVYVAQ-----DVQTGTEYALKRLIGADMQASTAIIN 94
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
E++ K L G++ IV+++ S T +G + LL E C GG L+D T
Sbjct: 95 EINIHKQLSGHENIVAFVGSSYTAPSTQLGA-QYLLLTELCKGGSLVDCFRTN-NAPFNP 152
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
+L I Q+++ VA++H+ PP+ HRDIKIEN L+ + + KLCDFGS S + +P T
Sbjct: 153 TCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSP--T 210
Query: 192 EEFNYVQYDIMKN-----TTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF 246
E++ Q ++++ TT YR PEM+D + PI K DIWALG LY CY P+
Sbjct: 211 FEWSANQRSMLEDQLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPY 270
Query: 247 EKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPI 306
E G+ I+ + + P P+Y ++I L+V+P +R +I V+E ++ +
Sbjct: 271 EDGGKLRIINANYMLPPDPQY-QCFSDIIRGCLKVNPFERLDITMVLEGLAAL----AET 325
Query: 307 KNFYLLRMMDKQEQPRVSPPPHVP 330
N+ L +D P S P P
Sbjct: 326 HNWSLKGPLDLHIMPIESLPAESP 349
>7298833 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 320
Score = 110 bits (275), Expect = 8e-24
Identities = 63/199 (31%), Positives = 108/199 (53%), Gaps = 9/199 (4%)
Query: 105 VYLLMEYCSGGGLIDFMN--TRLQNRLQEFEILNIMSQVSQGVAAMHALQP-PLIHRDIK 161
+++++ Y G L D + +R Q+ + E +IL I V +G+ A+H P PL HRD+K
Sbjct: 109 LFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLK 168
Query: 162 IENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGL 221
N+ LS + E + D GS++ + +Q + + ++ YR PE+ +
Sbjct: 169 TANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTYC 228
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFE---KNGES---AILASKFEFPAYPRYSDRVKNLI 275
IDE++DIW+LG LY CY+ +P++ + G+S A+L+ P Y++ + LI
Sbjct: 229 TIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELI 288
Query: 276 SVMLRVDPLKRPNICQVVE 294
MLR DP++RP + V+E
Sbjct: 289 KYMLRTDPMERPFVFSVIE 307
>CE04586 [T] KOG1989 ARK protein kinase family
Length = 570
Score = 103 bits (257), Expect = 1e-21
Identities = 75/261 (28%), Positives = 127/261 (47%), Gaps = 17/261 (6%)
Query: 5 QIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKA 64
Q E Y G + + +V K +A GGF V+ + V +K ++ D A
Sbjct: 22 QSELYDRGQTFSINGNNYRVEKVIAKGGFGTVFLATNTKGKQVA------VKIMLSHDAA 75
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
+ + E+D MK L+ ++ I+ D+ A N + E + MEYC +
Sbjct: 76 ATKDIDNEIDMMKKLQ-HENIIQLFDASAESRSSNRSVKEYKISMEYCK----FSIADVL 130
Query: 125 LQNRLQEFE-ILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVS- 182
L+ + + ++ I+ ++ + +H++ IHRDIK EN+L++ N + KLCDFGS +
Sbjct: 131 LKYKEVSIDFVVRIIYFTTRALVYLHSVGA--IHRDIKAENLLINGNGKLKLCDFGSATT 188
Query: 183 -GVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
+ AP + E VQ ++ K TT R PE+ D+Y PI ++ D WA+G +Y +
Sbjct: 189 KSIEMAPLSNSERLAVQEEMFKYTTPITRSPEVCDVYSNWPIGKQQDNWAMGCLIYFVAF 248
Query: 242 YTTPFEKNGESAILASKFEFP 262
PF+ AI+ K++ P
Sbjct: 249 GEHPFD-GSALAIINGKYKKP 268
>At5g08160 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 347
Score = 100 bits (250), Expect = 7e-21
Identities = 84/322 (26%), Positives = 153/322 (47%), Gaps = 42/322 (13%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSVE------------------ISPPDPVCPDNVACLKRV 58
+ ++ ++++ L GGFA V+ V+ + P + D +K+V
Sbjct: 23 INENRFRIVRQLGEGGFAFVFLVKEIVADASSAASGGGLAKKVKDPAHLSADGTYAMKKV 82
Query: 59 VVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVN----VGMYEVYLLMEYCSG 114
++ +K L +R E+ + +L + ++ +D HA S + +E +LL
Sbjct: 83 LIQNKEQLELVREEI-RVSSLFNHPNLLPLLD-HAIISVKDGQEGAWKHEAFLLFPVHLD 140
Query: 115 GGLIDFMNTRLQNRLQEF---EILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
G L+D T ++ + + F ++L+I Q+ G+ MH+L+PP H D+K NVLL++
Sbjct: 141 GTLLDNF-TLMKAKKETFSTTDVLHIFRQLCDGLKHMHSLEPPYAHNDVKPGNVLLTRRK 199
Query: 172 EFK----LCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKS 227
L DFGS + R+ +E +Q ++ +A +R PE+ D IDE++
Sbjct: 200 GQPPLAILMDFGSARPSRKQIRSRQEALQLQEWTSEHCSAPFRAPELWDCPSHADIDERT 259
Query: 228 DIWALGVFLYKTCYYTTPFE-KNGES------AILASKFEFP---AYPRYSDRVKNLISV 277
DIW+LG LY Y +PFE GES AI+ ++ ++P Y + + ++
Sbjct: 260 DIWSLGCTLYAIMYGVSPFEYALGESGGSLQLAIVNAQIKWPNTGPKASYPEALHQFVTW 319
Query: 278 MLRVDPLKRPNICQVVEEVSRI 299
ML+ RP I ++ V ++
Sbjct: 320 MLQPQAAVRPRIDDIIIHVDKL 341
>YPL236c [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 364
Score = 99.4 bits (246), Expect = 2e-20
Identities = 82/341 (24%), Positives = 149/341 (43%), Gaps = 61/341 (17%)
Query: 11 SGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVA-----CLKRVVVPDKAS 65
S + V + ++ + L GG + VY V++S + + +A LK+++ P S
Sbjct: 19 SDATIRVNDKRYRIQRLLGEGGMSFVYLVQLSKNSLIIDNGIATPELYALKKIICPSVES 78
Query: 66 LNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRL 125
++ E+++ K + + +++ IDS + G +Y+++ Y S G L D +N RL
Sbjct: 79 ISNGMREIENYKRFQ-SPYVIKSIDSQVMQE--KDGSKTIYIVLPYYSLGSLQDSINRRL 135
Query: 126 QNR--LQEFEILNIMSQVSQGVAAMH---------------------------------A 150
+ E E + IM V++G+ +H
Sbjct: 136 LEGTFVSEAECVRIMLGVTRGLLCLHDPASRQDNATSRVNVDAVSMTYSDETAMLLEDTP 195
Query: 151 LQPPLI-----------HRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQY 199
L+ ++ HRDI N+L S + + D GS S N + + +Q
Sbjct: 196 LEMDMLSSNSAGSIAYAHRDITPSNILFSSDGLPVIGDLGSCSQADITIENRHQLSELQE 255
Query: 200 DIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEK----NGES--- 252
+ N T Y PE+++L + K DIW+LG Y + +PFE+ +G S
Sbjct: 256 WVNDNCTLPYTPPELLNLKLNQVLSSKVDIWSLGCTFYTLMFGISPFEREEQIHGASLTY 315
Query: 253 AILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
AI K+ FP R+S+ + ++I ++VDP++RP Q++
Sbjct: 316 AINTGKYSFPRNSRFSEGLLSVIKKCIQVDPIQRPTTSQLL 356
>Hs17445015 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 305
Score = 91.7 bits (226), Expect = 4e-18
Identities = 76/300 (25%), Positives = 147/300 (48%), Gaps = 27/300 (9%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA 71
GT++ + + + ++ L GGF++V VE + + LKR++ ++ +
Sbjct: 11 GTVI-IDNKRYLFIQKLGEGGFSYVDLVE-----GLHDGHFYALKRILCHEQQDREEAQR 64
Query: 72 EVDSMKALRGNKFI--VSY-IDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
E D + + V+Y + K +E +LL+ + G L + + RL+++
Sbjct: 65 EADMHRLFNHPNILRLVAYCLRERGAK-------HEAWLLLPFFKRGTLWNEIE-RLKDK 116
Query: 129 ---LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVI 185
L E +IL ++ + +G+ A+HA HRD+K N+LL + L D GS++
Sbjct: 117 GNFLTEDQILWLLLGICRGLEAIHA--KGYAHRDLKPTNILLGDEGQPVLMDLGSMNQAC 174
Query: 186 RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
+ + +Q + T YR PE+ + IDE++D+W+LG LY + P
Sbjct: 175 IHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGP 234
Query: 246 FE---KNGESAILA--SKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQ 300
++ + G+S LA ++ P PR+S ++ L++ M+ VDP +RP+I ++ ++ +Q
Sbjct: 235 YDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQ 294
>SPAC3H1.13 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 344
Score = 91.3 bits (225), Expect = 5e-18
Identities = 83/333 (24%), Positives = 141/333 (41%), Gaps = 48/333 (14%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVP-D 62
P I ++ + + + ++ K L GGFA VY V+ V + + LK++
Sbjct: 14 PYISNLFDNDVVCINNERYRIQKLLGEGGFAFVYLVQ-----NVSNEKLYALKKIKCSFG 68
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM- 121
+ E D + + N + SY ++ G VY+L Y + G + +
Sbjct: 69 NKGIKKAMKEADYHRKFKSNYLLKSYTHQLVKEAD---GSEFVYILFPYFAKGSVAQVIR 125
Query: 122 NTRLQNR-LQEFEIL-------NIMSQVSQGVAAMHALQPPL------------------ 155
N ++ + E IL + + + VA QP +
Sbjct: 126 NCDIEGSYISEKRILVWCSCLCKALQYLHENVAGDSPKQPEVNDLIMFDEPQVPQNTSNN 185
Query: 156 -----IHRDIKIENVLLSKN-HEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQY 209
IH DIK +N+LL +N E L DFGS+ V N E +Q +N T +
Sbjct: 186 NLVSYIHGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASENCTMPF 245
Query: 210 RCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEK---NGESAILA---SKFEFPA 263
R PE+ + G I EK+DIW+ G LY ++ +PFE+ G S LA +++ FP
Sbjct: 246 RAPELFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQYSFPR 305
Query: 264 YPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV 296
YS + ++ L+ +P KRP+ +++ ++
Sbjct: 306 KHPYSTLLCEIVEACLQREPNKRPSARELLSKI 338
>Hs4505837 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 310
Score = 89.0 bits (219), Expect = 3e-17
Identities = 75/300 (25%), Positives = 146/300 (48%), Gaps = 27/300 (9%)
Query: 12 GTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA 71
GT++ + + + ++ L GGF++V VE + + LKR++ ++ +
Sbjct: 11 GTVI-IDNKRYLFIQKLGEGGFSYVDLVE-----GLHDGHFYALKRILCHEQQDREEAQR 64
Query: 72 EVDSMKALRGNKFI--VSY-IDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
E D + + V+Y + K +E +LL+ + G L + + RL+++
Sbjct: 65 EADMHRLFNHPNILRLVAYCLRERGAK-------HEAWLLLPFFKRGTLWNEIE-RLKDK 116
Query: 129 ---LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVI 185
L E +IL ++ + +G+ A+HA HRD+K N+LL + L D GS++
Sbjct: 117 GNFLTEDQILWLLLGICRGLEAIHA--KGYAHRDLKPTNILLGDEGQPVLMDLGSMNQAC 174
Query: 186 RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
+ + +Q + T YR PE+ + I E++D+W+LG LY + P
Sbjct: 175 IHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIGERTDVWSLGCVLYAMMFGEGP 234
Query: 246 FE---KNGESAILA--SKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQ 300
++ + G+S LA ++ P PR+S ++ L++ M+ VDP +RP+I ++ ++ +Q
Sbjct: 235 YDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQ 294
>Hs20547878 [R] KOG0589 Serine/threonine protein kinase
Length = 758
Score = 87.8 bits (216), Expect = 6e-17
Identities = 62/194 (31%), Positives = 97/194 (49%), Gaps = 18/194 (9%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++++MEYC GG L+ +N + E +IL Q+S G+ +H + ++HRDIK +N
Sbjct: 52 LFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRK--ILHRDIKAQN 109
Query: 165 VLLSKNHEF-KLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
+ LSKN KL DFG + R N+ E T Y PE+ + P
Sbjct: 110 IFLSKNGMVAKLGDFG----IARVLNNSMELARTCIG-----TPYYLSPEIC---QNKPY 157
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGESAI---LASKFEFPAYPRYSDRVKNLISVMLR 280
+ K+DIW+LG LY+ C PFE N + + P P +S + +LIS + +
Sbjct: 158 NNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQ 217
Query: 281 VDPLKRPNICQVVE 294
V P RP+I +++
Sbjct: 218 VSPRDRPSINSILK 231
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 87.4 bits (215), Expect = 7e-17
Identities = 76/271 (28%), Positives = 126/271 (46%), Gaps = 35/271 (12%)
Query: 24 VLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDS-MKALRGN 82
VL+ + G F V+ + + +K + +P K+ NT + ++ + A +
Sbjct: 6 VLRMIGEGSFGRALLVQHESSN-----QMFAMKEIRLP-KSFSNTQNSRKEAVLLAKMKH 59
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
IV++ +S + +Y++MEYC GG L+ + + E ILN +Q+
Sbjct: 60 PNIVAFKESFEAEG-------HLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMC 112
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEF--NYVQYD 200
GV +H + ++HRDIK +N+ L++N + KL DFGS R N F YV
Sbjct: 113 LGVNHIHKKR--VLHRDIKSKNIFLTQNGKVKLGDFGSA----RLLSNPMAFACTYVG-- 164
Query: 201 IMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFE 260
T Y PE ++ LP + KSDIW+LG LY+ C PF+ N ++ +
Sbjct: 165 -----TPYYVPPE---IWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQ 216
Query: 261 ---FPAYPRYSDRVKNLISVMLRVDPLKRPN 288
P YS ++ L+ M + +P RP+
Sbjct: 217 GCISPLPSHYSYELQFLVKQMFKRNPSHRPS 247
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 87.0 bits (214), Expect = 1e-16
Identities = 72/274 (26%), Positives = 124/274 (44%), Gaps = 29/274 (10%)
Query: 27 YLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIV 86
+L GGFA + ++ + VA + + + + L +E+ K++ + IV
Sbjct: 87 FLGEGGFARCFQIKDDSGEIFAAKTVA---KASIKSEKTRKKLLSEIQIHKSM-SHPNIV 142
Query: 87 SYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVA 146
+ID S VY+L+E C G L++ + R L E E+ +Q+ +
Sbjct: 143 QFIDCFEDDS-------NVYILLEICPNGSLMELLKRR--KVLTEPEVRFFTTQICGAIK 193
Query: 147 AMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTT 206
MH+ + +IHRD+K+ N+ N+ K+ DFG + + N E Y T
Sbjct: 194 YMHSRR--VIHRDLKLGNIFFDSNYNLKIGDFGLAAVL----ANESERKYTICG-----T 242
Query: 207 AQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL----ASKFEFP 262
Y PE++ + + + DIW+LGV LY PF+ + I F FP
Sbjct: 243 PNYIAPEVL-MGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFP 301
Query: 263 AYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV 296
SD K LI +L +DP++RP++ ++++ V
Sbjct: 302 RDKPISDEGKILIRDILSLDPIERPSLTEIMDYV 335
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 87.0 bits (214), Expect = 1e-16
Identities = 72/247 (29%), Positives = 114/247 (46%), Gaps = 34/247 (13%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
V L R + + +R E+ ++K R + I+ +T S +++++MEY
Sbjct: 56 VKILNRQKIKSLDVVGKIRREIQNLKLFR-HPHIIKLYQVISTPS-------DIFMIMEY 107
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
SGG L D++ +LQE + Q+ GV H + ++HRD+K EN+LL N
Sbjct: 108 VSGGELFDYIVKH--GKLQEHQARRFFQQIISGVDYCH--RHMIVHRDLKPENLLLDHNM 163
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDI 229
K+ DFG + ++ ++ + Y PE+I LY G + DI
Sbjct: 164 HVKIADFGLSNMMLDG----------EFLRTSCGSPNYAAPEVISGKLYAGPEV----DI 209
Query: 230 WALGVFLYKTCYYTTPFEKNGESA----ILASKFEFPAYPRYSDRVKNLISVMLRVDPLK 285
W+ GV LY T PF+ I + F P Y + +V NL+ ML+VDPLK
Sbjct: 210 WSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEY--LNKQVVNLVCQMLQVDPLK 267
Query: 286 RPNICQV 292
R NI ++
Sbjct: 268 RANIEEI 274
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 86.3 bits (212), Expect = 2e-16
Identities = 68/213 (31%), Positives = 105/213 (48%), Gaps = 23/213 (10%)
Query: 85 IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQG 144
I++Y DS + + + M EY GG L ++ R QN L E +I ++M Q+
Sbjct: 230 IIAYYDSFEEEGVLMIEM-------EYADGGTLAQMLS-RTQNLLDEEQIGDMMIQMCSA 281
Query: 145 VAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKN 204
VA +H + ++HRD+K NV L+++ K+ DFG I TE ++
Sbjct: 282 VAYLH--ENSVLHRDLKTANVFLTRDSFVKIGDFG-----ISKIMGTETLAQGAKTVVG- 333
Query: 205 TTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFE---F 261
T Y PEM G+ +EKSD+WALG LY+ C FE + A++ S
Sbjct: 334 -TPYYISPEMCS---GVSYNEKSDMWALGCILYEMCCLKKAFEGDNLPALVNSIMTCAYT 389
Query: 262 PAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
P YS +K +I +L++DP KRP+ Q ++
Sbjct: 390 PVKGPYSAEMKMVIRELLQLDPQKRPSAPQALK 422
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 84.7 bits (208), Expect = 5e-16
Identities = 79/310 (25%), Positives = 135/310 (43%), Gaps = 31/310 (10%)
Query: 6 IEKYASGTILPVGSH-QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKA 64
I Y G + GS +VKV +L +G + V PD A +
Sbjct: 122 IGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSE 181
Query: 65 SLNTLRAEVDS-MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
+R ++ + L + +I D + T S Y++ E+ GG ++D++ +
Sbjct: 182 KNKEIRTVREAALSTLLRHPYICEARDVYITNS-------HYYMVFEFVDGGQMLDYIIS 234
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
+L+E + + Q+ ++ +H Q ++HRD+KIEN+L+SK + K+ DFG +S
Sbjct: 235 H--GKLKEKQARKFVRQIGSALSYLH--QNSVVHRDLKIENILISKTGDIKIIDFG-LSN 289
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYT 243
+ R F Y + PE+++ I + D+W+ G+ LY
Sbjct: 290 LYRRQSRLRTFCGSLY---------FAAPELLNAQP--YIGPEVDVWSFGIVLYVLVCGK 338
Query: 244 TPFEKNGESAILA----SKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRI 299
PF+ SA+ A E+P+Y S K L+S ML DPLKR + +V+ I
Sbjct: 339 VPFDDQNMSALHAKIKKGTVEYPSY--LSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMI 396
Query: 300 QGIPCPIKNF 309
+ P +F
Sbjct: 397 RNYEGPPASF 406
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 84.3 bits (207), Expect = 6e-16
Identities = 82/289 (28%), Positives = 133/289 (45%), Gaps = 47/289 (16%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
D+A + L +E+ ++ L+ + Y VN VY++ME C+GG L +
Sbjct: 56 DEAKCDALVSEISVLRQLQHPNIVQYY------HHLVNREAKSVYIVMECCAGGDLAQIV 109
Query: 122 NTRLQNRLQEFE---ILNIMSQVSQGVAAMHALQP--PLIHRDIKIENVLLSKNHEFKLC 176
R +++ Q FE I ++ Q+ + + H P ++HRDIK N+ L KL
Sbjct: 110 Q-RARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLG 168
Query: 177 DFGSVSGVIRAPRNTEEF--NYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
DFG + R R + F ++V T Y PE++ +G D KSD+WA+G
Sbjct: 169 DFG----LARMLRRDQSFAASFVG-------TPHYMSPELV---KGRKYDRKSDVWAVGC 214
Query: 235 FLYKTCYYTTPFEKNG--ESAILASKFEFPAYPR-YSDRVKNLISVMLRVDPLKRPNI-- 289
+Y+ C PF + + ++ EF P YS ++ +I+ ML VD +RP I
Sbjct: 215 LVYEMCALRPPFRGRAFDQLSEKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEV 274
Query: 290 ----CQVVEEVSRIQGIPCPI-----KNFYLL----RMMDKQEQPRVSP 325
VV +S + G PI ++FY L R+ + +E+ V P
Sbjct: 275 IIRHPLVVRNISELDG-KFPILVDSGEDFYTLPSGARLFEDEEEDGVHP 322
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 83.6 bits (205), Expect = 1e-15
Identities = 69/241 (28%), Positives = 111/241 (45%), Gaps = 28/241 (11%)
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
+A L +EV+ ++ L+ + IV Y D ++ + Y++MEYC GG L +
Sbjct: 46 EAEKQMLVSEVNLLRELK-HPNIVRYYDRIIDRTNTTL-----YIVMEYCEGGDLASVIT 99
Query: 123 --TRLQNRLQEFEILNIMSQVSQGVAAMHALQP---PLIHRDIKIENVLLSKNHEFKLCD 177
T+ + L E +L +M+Q++ + H ++HRD+K NV L KL D
Sbjct: 100 KGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGD 159
Query: 178 FGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLY 237
FG + + F Y Y PE ++ + +EKSDIW+LG LY
Sbjct: 160 FGLARILNHDTSFAKTFVGTPY---------YMSPEQMNR---MSYNEKSDIWSLGCLLY 207
Query: 238 KTCYYTTPF----EKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+ C PF +K I KF Y RYSD + +I+ ML + RP++ +++
Sbjct: 208 ELCALMPPFTAFSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEIL 266
Query: 294 E 294
E
Sbjct: 267 E 267
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/244 (29%), Positives = 118/244 (48%), Gaps = 35/244 (14%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
+ +++ + D+ + +R E++ M +L + I+S + K ++ ++MEY
Sbjct: 83 IKSIRKDKIKDEQDMVHIRREIEIMSSLN-HPHIISIYEVFENKD-------KIVIIMEY 134
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
S G L D+++ R RL E E + Q+ V H + ++HRD+K+EN+LL N
Sbjct: 135 ASKGELYDYISER--RRLSERETRHFFRQIVSAVHYCH--KNGVVHRDLKLENILLDDNC 190
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDI 229
K+ DFG +S + + + + F + Y PE+++ YRG +D
Sbjct: 191 NIKIADFG-LSNLYQKDKFLQTF---------CGSPLYASPEIVNGRPYRGPEVDS---- 236
Query: 230 WALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLK 285
WALGV LY Y T PF+ KN I + ++ P P SD + LI ML V+P +
Sbjct: 237 WALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQP--SD-ARGLIRWMLMVNPDR 293
Query: 286 RPNI 289
R I
Sbjct: 294 RATI 297
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 82.8 bits (203), Expect = 2e-15
Identities = 64/237 (27%), Positives = 109/237 (45%), Gaps = 30/237 (12%)
Query: 66 LNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRL 125
L R E+ ++ + G+ +I+ D + + V+L+ E C G L D++ + +
Sbjct: 71 LEATRQEISILRQVMGHPYIIDLQDVFESDA-------FVFLVFELCPKGELFDYLTSVV 123
Query: 126 QNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVI 185
L E + IM Q+ +GV +HA ++HRD+K EN+LL +NH K+ DFG +
Sbjct: 124 T--LSEKKTRTIMRQIFEGVEYIHAKS--IVHRDLKPENILLDENHNVKITDFGFAKQLQ 179
Query: 186 RAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLP-IDEKSDIWALGVFLYKTCYY 242
+ T T Y PE + +++ G P ++ DIWA GV ++
Sbjct: 180 EGEKLTNLCG----------TPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVG 229
Query: 243 TTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
PF + +L + F P + S+ K+LI L VDP +R + +V+
Sbjct: 230 CPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVL 286
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 82.8 bits (203), Expect = 2e-15
Identities = 85/315 (26%), Positives = 133/315 (41%), Gaps = 63/315 (20%)
Query: 2 NQPQIEKYASGTILPVGS----------HQVKVLKYLASGGFA-------HVYSVEISPP 44
++P KY GT G+ H+ ++ K L SG + H + E++
Sbjct: 45 HEPTCSKYIYGTHPMSGAEPCSPTKKEKHRFEITKKLGSGTYGKVSLAYDHKFDREVA-- 102
Query: 45 DPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYE 104
V +K+ + KA L +R E+ M AL I Y V +
Sbjct: 103 -------VKLIKKSAIESKADLVRIRREIRIMSALNHPNIIQIY--------EVFENKDK 147
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+ L+MEY SGG L D+++ L E E I Q++ V H + + HRD+K+EN
Sbjct: 148 IILVMEYSSGGELYDYVSRC--GSLPEAEARRIFRQITSAVLYCHKHR--VAHRDLKLEN 203
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMID--LYR 219
+LL +N+ K+ DFG NY + T + Y PE+I+ Y+
Sbjct: 204 ILLDQNNNAKIADFGL-------------SNYFADKNLLTTFCGSPLYASPEIINGTPYK 250
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFEFPAY--PRYSDRVKNLISV 277
G + D W+LG+ LY Y + PF+ + + + + AY P LI
Sbjct: 251 GPEV----DCWSLGILLYTLVYGSMPFDGRDFNR-MVRQIKRGAYFEPETPSTASMLIRN 305
Query: 278 MLRVDPLKRPNICQV 292
MLRV+P +R I +
Sbjct: 306 MLRVNPERRATIFDI 320
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 82.4 bits (202), Expect = 2e-15
Identities = 84/294 (28%), Positives = 128/294 (42%), Gaps = 48/294 (16%)
Query: 8 KYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLN 67
++ S + VG++ K+LK + G F VY P CLK DK N
Sbjct: 29 QFTSDELTEVGNY--KILKQIGEGSFGKVYLALHRPTH-----RKVCLK---TSDKNDPN 78
Query: 68 TLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQN 127
+R + +F YI V V +V++ +EYC G L D + +
Sbjct: 79 IVR------EVFYHRQFDFPYITK---LYEVIVTESKVWMALEYCPGKELYDHLLSL--R 127
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
R+ E + +Q+S V H++ +HRD+K+EN+LL KN KL DFG
Sbjct: 128 RISLLECGELFAQISGAVYYAHSMH--CVHRDLKLENILLDKNGNAKLTDFGF------- 178
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
E + + TT Y PE+I+ Y G K DIW+LGV LY P
Sbjct: 179 --TRECMTKTTLETVCGTTV-YMAPELIERRTYDGF----KIDIWSLGVILYTLITGYLP 231
Query: 246 FEKNGESAIL------ASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
F+ + E+ K++ P D ++LIS +L +P +RP++ QV+
Sbjct: 232 FDDDDEAKTKWKIVNEEPKYDAKVIP---DDARDLISRLLAKNPGERPSLSQVL 282
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 81.3 bits (199), Expect = 5e-15
Identities = 76/301 (25%), Positives = 141/301 (46%), Gaps = 50/301 (16%)
Query: 23 KVLKY------LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNT----LRAE 72
++LKY + +GGFA V C + + + DK +L + ++ E
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLA--------CHILTGEMVAIKIMDKNTLGSDLPRIKTE 57
Query: 73 VDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEF 132
++++K LR Y H ++ ++++++EYC GG L D++ + Q+RL E
Sbjct: 58 IEALKNLRHQHICQLY---HVLETA-----NKIFMVLEYCPGGELFDYIIS--QDRLSEE 107
Query: 133 EILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTE 192
E + Q+ VA +H+ HRD+K EN+L + H+ KL DF G+ P+ +
Sbjct: 108 ETRVVFRQIVSAVAYVHS--QGYAHRDLKPENLLFDEYHKLKLIDF----GLCAKPKGNK 161
Query: 193 EFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNG 250
+++ + Y PE+I Y G ++D+W++G+ LY PF+ +
Sbjct: 162 DYHLQTC----CGSLAYAAPELIQGKSYLG----SEADVWSMGILLYVLMCGFLPFDDDN 213
Query: 251 ESA----ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPI 306
A I+ K++ P + S + L+ ML+VDP KR ++ ++ +Q P+
Sbjct: 214 VMALYKKIMRGKYDVPKWLSPSSIL--LLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPV 271
Query: 307 K 307
+
Sbjct: 272 E 272
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 80.9 bits (198), Expect = 7e-15
Identities = 73/251 (29%), Positives = 115/251 (45%), Gaps = 32/251 (12%)
Query: 50 DNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLM 109
D V +K VV + LN + AE+ +K L N IV Y KS YE+Y+L+
Sbjct: 48 DQVVAIKEVVYENDEELNDIMAEISLLKNLNHNN-IVKY-HGFIRKS------YELYILL 99
Query: 110 EYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSK 169
EYC+ G L ++ R L E E ++Q G+ +H +IHRDIK N+LLS
Sbjct: 100 EYCANGSLRRLIS-RSSTGLSENESKTYVTQTLLGLKYLHG--EGVIHRDIKAANILLSA 156
Query: 170 NHEFKLCDFGSVSGVIRAPRNT--EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKS 227
++ KL DFG VS ++ + T N++ +I+ N A S
Sbjct: 157 DNTVKLADFG-VSTIVNSSALTLAGTLNWMAPEILGNRGA----------------STLS 199
Query: 228 DIWALGVFLYKTCYYTTPFEKNGESAILASKFEFPAYP--RYSDRVKNLISVMLRVDPLK 285
DIW+LG + + P+ ++ I + YP +S+ +K+ +S + K
Sbjct: 200 DIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYK 259
Query: 286 RPNICQVVEEV 296
RP Q+++ V
Sbjct: 260 RPTADQLLKHV 270
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 80.9 bits (198), Expect = 7e-15
Identities = 87/304 (28%), Positives = 137/304 (44%), Gaps = 47/304 (15%)
Query: 5 QIEKYASGTILPVGSH-QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDK 63
+I Y G L VG+ +VKV K+ +G H +V+I L R +
Sbjct: 14 KIGHYILGDTLGVGTFGKVKVGKHELTG---HKVAVKI-------------LNRQKIRSL 57
Query: 64 ASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
+ +R E+ ++K R + I+ +T S +++++MEY SGG L D++
Sbjct: 58 DVVGKIRREIQNLKLFR-HPHIIKLYQVISTPS-------DIFMVMEYVSGGELFDYICK 109
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
RL E E + Q+ GV H + ++HRD+K ENVLL + K+ DFG
Sbjct: 110 N--GRLDEKESRRLFQQILSGVDYCH--RHMVVHRDLKPENVLLDAHMNAKIADFG---- 161
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCY 241
+ + EF + Y PE+I LY G + DIW+ GV LY
Sbjct: 162 -LSNMMSDGEFLRTSCG-----SPNYAAPEVISGRLYAGPEV----DIWSSGVILYALLC 211
Query: 242 YTTPFEKNGESAILASKFEFPAY-PRY-SDRVKNLISVMLRVDPLKRPNICQVVEEVSRI 299
T PF+ + + + Y P+Y + V +L+ ML+VDP+KR +I + E
Sbjct: 212 GTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRASIKDIREHEWFK 271
Query: 300 QGIP 303
Q +P
Sbjct: 272 QDLP 275
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 80.9 bits (198), Expect = 7e-15
Identities = 80/283 (28%), Positives = 133/283 (46%), Gaps = 38/283 (13%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSV-EISPPDPVCPDNVACLKRVVVPDKASLNT-LRAEVD 74
VG ++LK L +G + V+ V +IS D + LK+ + KA R E
Sbjct: 44 VGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQ 103
Query: 75 SMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEI 134
++ +R + F+V+ + T++ +++L+++Y +GG L ++ R R E E+
Sbjct: 104 VLEHIRQSPFLVTLHYAFQTET-------KLHLILDYINGGELFTHLSQR--ERFTEHEV 154
Query: 135 LNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEF 194
+ ++ + +H L +I+RDIK+EN+LL N L DFG +S A +
Sbjct: 155 QIYVGEIVLALEHLHKLG--IIYRDIKLENILLDSNGHVVLTDFG-LSKEFVADETERAY 211
Query: 195 NYVQYDIMKNTTAQYRCPEMIDLYRG--LPIDEKSDIWALGVFLYKTCYYTTPFEKNGES 252
++ T +Y P D+ RG D+ D W+LGV +Y+ +PF +GE
Sbjct: 212 SFC-------GTIEYMAP---DIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEK 261
Query: 253 --------AILASKFEFPAYPR-YSDRVKNLISVMLRVDPLKR 286
IL S+ P YP+ S K+LI +L DP KR
Sbjct: 262 NSQAEISRRILKSE---PPYPQEMSALAKDLIQRLLMKDPKKR 301
Score = 67.8 bits (164), Expect = 6e-11
Identities = 67/245 (27%), Positives = 105/245 (42%), Gaps = 42/245 (17%)
Query: 59 VVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLI 118
++ + NT + E+ ++K G+ IV + V +L+ME +GG L
Sbjct: 456 IISKRMEANTQK-EITALKLCEGHPNIVKLHE-------VFHDQLHTFLVMELLNGGELF 507
Query: 119 DFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSK---NHEFKL 175
D + R + E E IM ++ ++ MH L ++HRD+K EN+L + N E K+
Sbjct: 508 DAL--RKKKHFSETEASYIMRKLVSALSHMHDLG--VVHRDLKPENLLFTDENDNLEIKI 563
Query: 176 CDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRC-PEMIDLYRGLPIDEKSDIWALGV 234
DFG ++ P N + + C PE+++ DE D+W+LGV
Sbjct: 564 IDFGFAR--LKPPDNQP--------LKTPCFTLHSCRPELLNQNG---YDESCDLWSLGV 610
Query: 235 FLYKTCYYTTPFEKNGESAILAS-------------KFEFPAYPRYSDRVKNLISVMLRV 281
LY PF+ + S S FE A+ S K+LI +L V
Sbjct: 611 ILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTV 670
Query: 282 DPLKR 286
DP KR
Sbjct: 671 DPNKR 675
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 79.7 bits (195), Expect = 2e-14
Identities = 86/306 (28%), Positives = 130/306 (42%), Gaps = 51/306 (16%)
Query: 5 QIEKYASGTILPVGSH-QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDK 63
+I Y G L VG+ +VK+ ++ +G H +V+I L R +
Sbjct: 12 KIGHYVLGDTLGVGTFGKVKIGEHQLTG---HKVAVKI-------------LNRQKIRSL 55
Query: 64 ASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
+ ++ E+ ++K R I Y +P + +++MEY SGG L D++
Sbjct: 56 DVVGKIKREIQNLKLFRHPHIIKLY---QVISTPT-----DFFMVMEYVSGGELFDYICK 107
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
R++E E + Q+ V H + ++HRD+K ENVLL + K+ DFG
Sbjct: 108 H--GRVEEMEARRLFQQILSAVDYCH--RHMVVHRDLKPENVLLDAHMNAKIADFG---- 159
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCY 241
+ + EF + Y PE+I LY G + DIW+ GV LY
Sbjct: 160 -LSNMMSDGEFLRTSCG-----SPNYTAPEVISGRLYAGPEV----DIWSCGVILYALLC 209
Query: 242 YTTPFEKNGE----SAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVS 297
T PF+ I F P Y S V L+ ML+VDPLKR I + E
Sbjct: 210 GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS--VATLLMHMLQVDPLKRATIKDIREHEW 267
Query: 298 RIQGIP 303
QG+P
Sbjct: 268 FKQGLP 273
>CE03103 [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated
factor
Length = 283
Score = 79.7 bits (195), Expect = 2e-14
Identities = 65/252 (25%), Positives = 114/252 (44%), Gaps = 17/252 (6%)
Query: 55 LKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSG 114
+K++V K + E+D K L N+F++ + +H + YLL + S
Sbjct: 14 VKKMVAFSKREEERILLEIDLYKKLENNEFVIDLM-AHIVDDITH------YLLFDKYSQ 66
Query: 115 GGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFK 174
L ++ + E + L S + + +H + H DIK N+L S + K
Sbjct: 67 NFLEYIEELKIGGEVDELKHLKYFSGIVSAIEQLHGFE--FAHLDIKPANILKSGD-TIK 123
Query: 175 LCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
+ DFGS + + + + + + + D + + YR PE+ + G + D+WALGV
Sbjct: 124 MIDFGSATKMPIEIKTSADHHRHKEDAEELCSMMYRAPELFNCEIGSTLTTAVDVWALGV 183
Query: 235 FLYKTCYYTTPFEK---NGESAILASK----FEFPAYPRYSDRVKNLISVMLRVDPLKRP 287
LY+ Y PF K G S LA++ ++ S++ NLI +L VDP +RP
Sbjct: 184 CLYEFLYLENPFNKIYEQGGSIALATQSPHMIKWNENRHISEKSINLIKSILIVDPNQRP 243
Query: 288 NICQVVEEVSRI 299
I ++ +V +
Sbjct: 244 TIGELRAKVDNL 255
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/206 (29%), Positives = 100/206 (48%), Gaps = 26/206 (12%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
Y+L EY SGG L+D++ ++E + ++ + +HA ++HRD+KIEN+
Sbjct: 220 YMLFEYVSGGQLLDYIIQH--GSIREHQARKFARGIASALIYLHANN--IVHRDLKIENI 275
Query: 166 LLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPI 223
++S + E K+ DFG +S + + + F Y + PE++ + Y G +
Sbjct: 276 MISDSSEIKIIDFG-LSNIYDSRKQLHTFCGSLY---------FAAPELLKANPYTGPEV 325
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGESA----ILASKFEFPAYPRYSDRVKNLISVML 279
D+W+ GV L+ PF+ S I K E+P + S V +L+S ML
Sbjct: 326 ----DVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQH--LSIEVISLLSKML 379
Query: 280 RVDPLKRPNICQVVEEVSRIQGIPCP 305
VDP +R + QVVE ++G P
Sbjct: 380 VVDPKRRATLKQVVEHHWMVRGFNGP 405
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/294 (26%), Positives = 131/294 (43%), Gaps = 51/294 (17%)
Query: 6 IEKYASGTILPVGSH-QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKA 64
+ Y G L +GS +VK+ +++ +G H +++I L R + +
Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTG---HKVAIKI-------------LNRRKIKNME 60
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
+R E+ ++ I Y T ++Y++MEY G L D++ +
Sbjct: 61 MEEKVRREIKILRLFMHPHIIRQYEVIETTS--------DIYVVMEYVKSGELFDYIVEK 112
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
RLQE E N Q+ GV H + ++HRD+K EN+LL K+ DFG +S V
Sbjct: 113 --GRLQEDEARNFFQQIISGVEYCH--RNMVVHRDLKPENLLLDSRCNIKIADFG-LSNV 167
Query: 185 IRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCYY 242
+R + ++++ + Y PE+I LY G + D+W+ GV LY
Sbjct: 168 MR------DGHFLKTSC---GSPNYAAPEVISGKLYAGPEV----DVWSCGVILYALLCG 214
Query: 243 TTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
T PF+ N I + P++ S ++LI ML VDP+KR I ++
Sbjct: 215 TLPFDDENIPNLFKKIKGGIYTLPSH--LSSEARDLIPRMLIVDPVKRITIPEI 266
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 79.3 bits (194), Expect = 2e-14
Identities = 61/197 (30%), Positives = 88/197 (43%), Gaps = 29/197 (14%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++L++EY GG L + + L E + ++ +SQ +A H +IHRDIK EN
Sbjct: 95 IFLILEYAHGGELYGVL--KQNGHLTEQQAATYIASLSQALAYCHG--KCVIHRDIKPEN 150
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGL 221
+LL K+ DFG VQ + T T Y PEM++
Sbjct: 151 LLLDHEGRLKIADFGWS---------------VQSSNKRKTMCGTLDYLAPEMVE---NR 192
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEFPAYPRYSDRVKNLISV 277
D D W LG+ Y+ Y PFE + IL FP P S+ KNLIS
Sbjct: 193 DHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAKNLISQ 252
Query: 278 MLRVDPLKRPNICQVVE 294
+L DP KR +I ++++
Sbjct: 253 LLVKDPSKRLSIEKIMQ 269
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 79.0 bits (193), Expect = 3e-14
Identities = 84/301 (27%), Positives = 130/301 (42%), Gaps = 47/301 (15%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVP-- 61
P K + +L VG ++++ K + G FA V N+ +V +
Sbjct: 25 PSTSKISVDKLLRVGYYELE--KTIGKGNFAVVKLAT----------NIVTKTKVAIKII 72
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKS-PVNVGMYEVYLLMEYCSGGGLIDF 120
DK LN E K R + S H T+ V +YL+ EY G + D
Sbjct: 73 DKTCLN----EEYLNKTFREIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDH 128
Query: 121 MNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGS 180
+ R++E E + +Q+ V H + ++HRD+K ENVLL K+ KL DFG
Sbjct: 129 LVAN--GRMKEPEAARVFTQLVSAVHYCH--RRGVVHRDLKAENVLLDKDMNIKLADFGF 184
Query: 181 VSGVIRAPRNTEEFNYVQYDIMKN--TTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLY 237
+ +Y + +K + Y PE +++GL D KSDIW+LGV LY
Sbjct: 185 SN------------HYEEGATLKTWCGSPPYAAPE---VFQGLEYDGPKSDIWSLGVVLY 229
Query: 238 KTCYYTTPFEKNG----ESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
PF+ +S ++ KF P + S + LI ML V+P +R I Q++
Sbjct: 230 ALVCGALPFDGKTILELKSRVVLGKFRIPFF--MSQECEQLIRNMLVVEPDRRYTIKQII 287
Query: 294 E 294
+
Sbjct: 288 K 288
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 79.0 bits (193), Expect = 3e-14
Identities = 71/243 (29%), Positives = 110/243 (45%), Gaps = 27/243 (11%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
+ +K+ + +A L +R EV M ++ I Y V ++ L+ME+
Sbjct: 110 IKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIY--------EVFENREKMVLVMEF 161
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
+GG L D+++ R L E E I QV+ V H + + HRD+K+EN+LL +
Sbjct: 162 AAGGELYDYLSER--KVLTEEEARRIFRQVATAVYYCH--KHKICHRDLKLENILLDEKG 217
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIW 230
K+ DFG +S V R F + Y PE+++ G P + D W
Sbjct: 218 NAKIADFG-LSNVFDDQRLLGTF---------CGSPLYASPEIVE---GTPYQGPEVDCW 264
Query: 231 ALGVFLYKTCYYTTPFEKNGESAILASKFEFPAY-PRYSDRVKNLISVMLRVDPLKRPNI 289
+LGV LY Y + PF+ + ++ + Y PR R LI ML V P KR +I
Sbjct: 265 SLGVLLYTLVYGSMPFDGSNFKRLVKQISQGDYYEPRKPSRASTLIRDMLTVCPRKRASI 324
Query: 290 CQV 292
Q+
Sbjct: 325 EQI 327
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 78.6 bits (192), Expect = 3e-14
Identities = 62/195 (31%), Positives = 98/195 (49%), Gaps = 26/195 (13%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
++YL+MEY + G L D++ + RLQE E N Q+ GV H + ++HRD+K E
Sbjct: 91 DIYLVMEYVNSGELFDYIVEK--GRLQEDEARNFFQQIISGVEYCH--RNMVVHRDLKPE 146
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGL 221
N+LL K+ DFG +S ++R + ++++ + Y PE+I LY G
Sbjct: 147 NLLLDSKCNVKIADFG-LSNIMR------DGHFLKTSC---GSPNYAAPEVISGKLYAGP 196
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISV 277
+ D+W+ GV LY T PF+ N I + P++ S ++LI
Sbjct: 197 EV----DVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSH--LSPGARDLIPR 250
Query: 278 MLRVDPLKRPNICQV 292
ML VDP+KR I ++
Sbjct: 251 MLVVDPMKRVTIPEI 265
>At1g73660 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 1030
Score = 78.6 bits (192), Expect = 3e-14
Identities = 65/256 (25%), Positives = 116/256 (44%), Gaps = 39/256 (15%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
+L R+EV MK LR ++ A P N+ ++ E+ G L ++ R
Sbjct: 786 ALEEFRSEVRIMKKLRHPNIVLFM---GAVTRPPNLS-----IVTEFLPRGSLYRLIH-R 836
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
N+L E L + ++G+ +H+ P ++HRD+K N+L+ KN K+CDFG
Sbjct: 837 PNNQLDERRRLRMALDAARGMNYLHSCNPMIVHRDLKSPNLLVDKNWVVKVCDFG----- 891
Query: 185 IRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYY 242
+ Y K+T TA++ PE++ R P DEK D+++ GV L++
Sbjct: 892 ------LSRMKHSTYLSSKSTAGTAEWMAPEVL---RNEPADEKCDVYSYGVILWELFTL 942
Query: 243 TTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV 296
P+ K ++ + + + P + + +LIS + D RP+ +++ +
Sbjct: 943 QQPWGKMNPMQVVGAVGFQHRRLDIPDF--VDPAIADLISKCWQTDSKLRPSFAEIMASL 1000
Query: 297 SRIQ------GIPCPI 306
R+Q IP P+
Sbjct: 1001 KRLQKPVTGSNIPRPV 1016
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 78.2 bits (191), Expect = 5e-14
Identities = 60/192 (31%), Positives = 96/192 (49%), Gaps = 22/192 (11%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+Y+ +E C GG L D + + RL E E ++V + +H++ LIHRDIK EN
Sbjct: 114 LYMALESCEGGELFDQITRK--GRLSEDEARFYTAEVVDALEYIHSMG--LIHRDIKPEN 169
Query: 165 VLLSKNHEFKLCDFGSV-----SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
+LL+ + K+ DFGSV S + P + + TA Y PE+++
Sbjct: 170 LLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTF----VGTAAYVPPEVLN--- 222
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE----SAILASKFEFPAYPRYSDRVKNLI 275
P +D+WALG LY+ T+PF+ E I+A +FP + +S+ ++LI
Sbjct: 223 SSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNH--FSEAARDLI 280
Query: 276 SVMLRVDPLKRP 287
+L +P +RP
Sbjct: 281 DRLLDTEPSRRP 292
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 77.8 bits (190), Expect = 6e-14
Identities = 61/192 (31%), Positives = 95/192 (48%), Gaps = 22/192 (11%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+Y+ +E C GG L D + + RL E E ++V + +H + LIHRDIK EN
Sbjct: 115 LYMALESCEGGELFDQITRK--GRLSEDEARFYSAEVVDALEYIHNMG--LIHRDIKPEN 170
Query: 165 VLLSKNHEFKLCDFGSV-----SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
+LL+ + K+ DFGSV S + P + + TA Y PE+++
Sbjct: 171 LLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDDKACTF----VGTAAYVPPEVLN--- 223
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE----SAILASKFEFPAYPRYSDRVKNLI 275
P +D+WALG LY+ T+PF+ E I+A +FP + +S+ ++LI
Sbjct: 224 SSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPNH--FSEAARDLI 281
Query: 276 SVMLRVDPLKRP 287
+L DP +RP
Sbjct: 282 DRLLDTDPSRRP 293
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 77.0 bits (188), Expect = 1e-13
Identities = 69/229 (30%), Positives = 110/229 (47%), Gaps = 30/229 (13%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSH-ATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQN 127
LR EV+ LR + Y H AT+ VYL++EY G + + + +
Sbjct: 177 LRREVEIQSHLRHPNILRLYGYFHDATR---------VYLILEYAPLGTV--YRELQKLS 225
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
+ E N+ ++++ ++ H+ + +IHRDIK EN+LL E K+ DFG + A
Sbjct: 226 KFDEQRTANLYNRIANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFG---WSVHA 280
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFE 247
P + T Y PEMI+ G DEK D+W+LGV Y+ PFE
Sbjct: 281 PSSRR--------TTLCGTLDYLPPEMIE---GRMHDEKVDLWSLGVLCYEFLVGKPPFE 329
Query: 248 KN--GESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
N E+ S+ EF ++ ++LIS +L+ +P +RP + +V+E
Sbjct: 330 ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLE 378
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 77.0 bits (188), Expect = 1e-13
Identities = 53/168 (31%), Positives = 87/168 (51%), Gaps = 14/168 (8%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E++ +K ++ I +Y + KSP +++L+ME+C G + D + N
Sbjct: 66 IKQEINMLKKYSHHRNIATYYGAFIKKSPPG-NDDQLWLVMEFCGAGSVTDLVKNTKGNA 124
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L+E I I ++ +G+A +HA + +IHRDIK +NVLL++N E KL DFG + + R
Sbjct: 125 LKEDCIAYICREILRGLAHLHAHK--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV 182
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
F Y + PE+I D D +SDIW+LG+
Sbjct: 183 GRRNTFIGTPY---------WMAPEVIACDENPDATYDYRSDIWSLGI 221
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 77.0 bits (188), Expect = 1e-13
Identities = 74/275 (26%), Positives = 124/275 (44%), Gaps = 36/275 (13%)
Query: 20 HQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKAL 79
H+ + L+ L G + V S V + +++ + D+ L +R E++ M +L
Sbjct: 51 HRYEFLETLGKGTYGKVKKARESSGRLVA---IKSIRKDKIKDEQDLMHIRREIEIMSSL 107
Query: 80 RGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMS 139
I + V ++ ++MEY S G L D+++ R Q L E E +
Sbjct: 108 NHPHIIAIH--------EVFENSSKIVIVMEYASRGDLYDYISERQQ--LSEREARHFFR 157
Query: 140 QVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQY 199
Q+ V H Q ++HRD+K+EN+LL N K+ DFG +S + + + F
Sbjct: 158 QIVSAVHYCH--QNRVVHRDLKLENILLDANGNIKIADFG-LSNLYHQGKFLQTF----- 209
Query: 200 DIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS 257
+ Y PE+++ Y G +D W+LGV LY + T PF+ + + IL
Sbjct: 210 ----CGSPLYASPEIVNGKPYTGPEVDS----WSLGVLLYILVHGTMPFDGH-DHKILVK 260
Query: 258 KFEFPAY---PRYSDRVKNLISVMLRVDPLKRPNI 289
+ AY P+ SD LI +L V+P +R +
Sbjct: 261 QISNGAYREPPKPSDAC-GLIRWLLMVNPTRRATL 294
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 77.0 bits (188), Expect = 1e-13
Identities = 69/238 (28%), Positives = 110/238 (45%), Gaps = 33/238 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
S+ +R EV ++AL G++ +V + D+ + VY++ME C GG L+D + R
Sbjct: 188 SIEDVRREVKILRALSGHQNLVQFYDAFEDNA-------NVYIVMELCGGGELLDRILAR 240
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSV 181
+ E + ++ Q+ VA H ++HRD+K EN L + E K+ DFG
Sbjct: 241 -GGKYSEDDAKAVLIQILNVVAFCHL--QGVVHRDLKPENFLYTSKEENSMLKVIDFGLS 297
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
V R E N DI+ +A Y PE+ L+R + +D+W++GV Y
Sbjct: 298 DFV----RPDERLN----DIV--GSAYYVAPEV--LHRSYTTE--ADVWSIGVIAYILLC 343
Query: 242 YTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+ PF ES I + F+ P +P S K+ + +L DP KR Q +
Sbjct: 344 GSRPFWARTESGIFRAVLKADPSFDEPPWPSLSFEAKDFVKRLLYKDPRKRMTASQAL 401
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 77.0 bits (188), Expect = 1e-13
Identities = 77/287 (26%), Positives = 128/287 (43%), Gaps = 42/287 (14%)
Query: 20 HQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLK----RVVVPDKASLNTLRAEVDS 75
H+ + K L G F + Y D D VA K ++ +P ++ ++ EV
Sbjct: 106 HRYTIGKLLGHGQFGYTYVAT----DKKTGDRVAVKKIDKAKMTIP--IAVEDVKREVKI 159
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEIL 135
++AL G++ +V + ++ K+ VY++ME C GG L+D + R +R E +
Sbjct: 160 LQALTGHENVVRFYNAFEDKN-------SVYIVMELCEGGELLDRILARKDSRYSERDAA 212
Query: 136 NIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSVSGVIRAPRNTE 192
++ Q+ + A H L+HRD+K EN L E K DFG +S I+ +
Sbjct: 213 VVVRQMLKVAAECHL--RGLVHRDMKPENFLFKSTEEDSPLKATDFG-LSDFIKPGKKF- 268
Query: 193 EFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES 252
+DI+ +A Y PE++ G +SD+W++GV Y PF E
Sbjct: 269 ------HDIV--GSAYYVAPEVLKRRSG----PESDVWSIGVISYILLCGRRPFWDKTED 316
Query: 253 AI----LASKFEF--PAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
I L +K +F +P S+ K+ + +L DP R Q +
Sbjct: 317 GIFKEVLKNKPDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQAL 363
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 77.0 bits (188), Expect = 1e-13
Identities = 58/220 (26%), Positives = 102/220 (46%), Gaps = 25/220 (11%)
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
E++ + +R + FIV Y DS K+ V +++ YC GG + + QE
Sbjct: 51 EMELISKMR-HPFIVEYKDSWVEKACY------VCIVIGYCEGGDMAQAIKKSNGVHFQE 103
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
++ + Q+ G+ +H+ ++HRD+K N+ L+K + +L DFG ++ ++ + T
Sbjct: 104 EKLCKWLVQLLMGLEYLHSNH--ILHRDVKCSNIFLTKEQDIRLGDFG-LAKILTSDDLT 160
Query: 192 EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE 251
T Y CPE++ +P KSDIW+LG +Y+ Y F+
Sbjct: 161 SSV---------VGTPSYMCPELL---ADIPYGSKSDIWSLGCCIYEMAYLKPAFKAFDM 208
Query: 252 SAI---LASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPN 288
A+ + P +YS + L+ MLR +P RP+
Sbjct: 209 QALINKINKTIVSPLPAKYSGPFRGLVKSMLRKNPEVRPS 248
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 77.0 bits (188), Expect = 1e-13
Identities = 70/249 (28%), Positives = 111/249 (44%), Gaps = 27/249 (10%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
V + +V P + + L E++++K L I Y + + VYL+M+
Sbjct: 96 VKIISKVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETS--------HRVYLIMQL 147
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
G L+D++ R L E + + Q+ V +H+ ++HRDIK EN+LL +N
Sbjct: 148 AENGTLLDYVRER--KFLDEPQSRTLFKQLVSAVEYIHS--KGVVHRDIKCENLLLDENW 203
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDE-KSDIW 230
KL DF G R T + + + A Y PE++ +G+ D SDIW
Sbjct: 204 NLKLIDF----GFARKDTRTSDNQVILSKTFCGSYA-YASPEIL---KGVAYDPFMSDIW 255
Query: 231 ALGVFLYKTCYYTTPFEKNGESAILA---SKFEFPAYPRYSDRVKNLISVMLRVDPLK-R 286
A GV Y + P++ + +L FP P S K++I +L P+K R
Sbjct: 256 ACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSPSASSECKHMIMHILA--PVKIR 313
Query: 287 PNICQVVEE 295
NI QV E+
Sbjct: 314 YNIPQVKED 322
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 77.0 bits (188), Expect = 1e-13
Identities = 68/259 (26%), Positives = 116/259 (44%), Gaps = 30/259 (11%)
Query: 15 LPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPD-KASLNTLRAEV 73
+ +G +++ ++ L G F V+ + P+ C+KR++V + K L ++ EV
Sbjct: 1 MELGDSKLRAVRVLGQGTFGRVFLCHQNEVRGQ-PERKVCVKRIIVRNPKTELGLIKEEV 59
Query: 74 DSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR--LQE 131
+ LR + IV ++ S + VN+ +MEY G L D + + +
Sbjct: 60 YIISQLR-HPHIVEFLRSFSHAGTVNI-------VMEYVPNGTLRDVIQQLPSGTGGVNQ 111
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
++ + G+ +H +IHRDIK EN+LL N K+ DFG + + AP
Sbjct: 112 ERLMGYFRDMVVGLEYLHIRC--VIHRDIKPENMLLDANDRVKIADFGIAN--VHAPSTQ 167
Query: 192 EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF----E 247
+ T Y PE + +D KSD+W+LG+ LY+ C +PF +
Sbjct: 168 LQAGM--------GTPMYMAPEAMSSQG--KVDFKSDVWSLGLVLYELCLGRSPFAAFLD 217
Query: 248 KNGESAILASKFEFPAYPR 266
KN A+L + + PR
Sbjct: 218 KNATPALLHTVVQALVRPR 236
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 76.6 bits (187), Expect = 1e-13
Identities = 63/228 (27%), Positives = 110/228 (47%), Gaps = 33/228 (14%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
E+YL++EY GG L D++ ++ +L E E ++ Q+ +GV+ H+ + HRD+K E
Sbjct: 188 ELYLVLEYVDGGELFDYLVSK--GKLPEREAIHYFKQIVEGVSYCHSFN--ICHRDLKPE 243
Query: 164 NVLL-SKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMI--DLY 218
N+LL KN K+ DFG + + P ++K + + Y PE++ Y
Sbjct: 244 NLLLDKKNRRIKIADFGMAA--LELPNK----------LLKTSCGSPHYASPEIVMGRPY 291
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL----ASKFEFPAYPRYSDRVKNL 274
G P SD+W+ G+ L+ PF + +L + K++ P+ S ++L
Sbjct: 292 HGGP----SDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPS--NLSSEARDL 345
Query: 275 ISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMDKQEQPR 322
IS +L +DP KR ++++ + P+ +LR M K R
Sbjct: 346 ISKILVIDPEKRITTQEILKHPLIKKYDDLPVNK--VLRKMRKDNMAR 391
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 76.6 bits (187), Expect = 1e-13
Identities = 67/236 (28%), Positives = 106/236 (44%), Gaps = 32/236 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
SL L EV MK L + + K+ +YL+MEY SGG + D++
Sbjct: 96 SLQKLFREVRIMKILNHPNIVKLFEVIETQKT--------LYLIMEYASGGKVFDYLVAH 147
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
R++E E + Q+ V H Q ++HRD+K EN+LL + K+ DFG
Sbjct: 148 --GRMKEKEARSKFRQIVSAVQYCH--QKRIVHRDLKAENLLLDADMNIKIADFGF---- 199
Query: 185 IRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTCYYT 243
+ EF + Y PE L++G D + D+W+LGV LY +
Sbjct: 200 ------SNEFTVGGKLDTFCGSPPYAAPE---LFQGKKYDGPEVDVWSLGVILYTLVSGS 250
Query: 244 TPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
PF+ K +L K+ P Y S +NL+ L ++P+KR + Q++++
Sbjct: 251 LPFDGQNLKELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 76.6 bits (187), Expect = 1e-13
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 32/239 (13%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
+ +SL L EV MK L + + K+ +YL+MEY SGG + D++
Sbjct: 57 NSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKT--------LYLVMEYASGGEVFDYL 108
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
R++E E Q+ V H Q ++HRD+K EN+LL + K+ DFG
Sbjct: 109 VAH--GRMKEKEARAKFRQIVSAVQYCH--QKFIVHRDLKAENLLLDADMNIKIADFGF- 163
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTC 240
+ EF + + Y PE L++G D + D+W+LGV LY
Sbjct: 164 ---------SNEFTFGNKLDTFCGSPPYAAPE---LFQGKKYDGPEVDVWSLGVILYTLV 211
Query: 241 YYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ PF+ K +L K+ P Y S +NL+ L ++P KR + Q++++
Sbjct: 212 SGSLPFDGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 268
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 76.6 bits (187), Expect = 1e-13
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 32/239 (13%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
+ +SL L EV MK L + + K+ +YL+MEY SGG + D++
Sbjct: 57 NSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKT--------LYLVMEYASGGEVFDYL 108
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
R++E E Q+ V H Q ++HRD+K EN+LL + K+ DFG
Sbjct: 109 VAH--GRMKEKEARAKFRQIVSAVQYCH--QKFIVHRDLKAENLLLDADMNIKIADFGF- 163
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTC 240
+ EF + + Y PE L++G D + D+W+LGV LY
Sbjct: 164 ---------SNEFTFGNKLDTFCGSPPYAAPE---LFQGKKYDGPEVDVWSLGVILYTLV 211
Query: 241 YYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ PF+ K +L K+ P Y S +NL+ L ++P KR + Q++++
Sbjct: 212 SGSLPFDGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 268
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 76.6 bits (187), Expect = 1e-13
Identities = 67/236 (28%), Positives = 107/236 (44%), Gaps = 32/236 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
SL L EV MK L + + K+ +YL+MEY SGG + D++
Sbjct: 100 SLQKLFREVRIMKILNHPNIVKLFEVIETEKT--------LYLVMEYASGGEVFDYLVAH 151
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
R++E E Q+ V H Q ++HRD+K EN+LL + K+ DFG
Sbjct: 152 --GRMKEKEARAKFRQIVSAVQYCH--QKYIVHRDLKAENLLLDGDMNIKIADFGF---- 203
Query: 185 IRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTCYYT 243
+ EF + Y PE L++G D + D+W+LGV LY +
Sbjct: 204 ------SNEFTVGNKLDTFCGSPPYAAPE---LFQGKKYDGPEVDVWSLGVILYTLVSGS 254
Query: 244 TPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
PF+ K +L K+ P Y S +NL+ +L ++P+KR ++ Q++++
Sbjct: 255 LPFDGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 76.6 bits (187), Expect = 1e-13
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 32/239 (13%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
+ +SL L EV MK L + + K+ +YL+MEY SGG + D++
Sbjct: 90 NSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKT--------LYLVMEYASGGEVFDYL 141
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
R++E E Q+ V H Q ++HRD+K EN+LL + K+ DFG
Sbjct: 142 VAH--GRMKEKEARAKFRQIVSAVQYCH--QKFIVHRDLKAENLLLDADMNIKIADFGF- 196
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTC 240
+ EF + + Y PE L++G D + D+W+LGV LY
Sbjct: 197 ---------SNEFTFGNKLDTFCGSPPYAAPE---LFQGKKYDGPEVDVWSLGVILYTLV 244
Query: 241 YYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ PF+ K +L K+ P Y S +NL+ L ++P KR + Q++++
Sbjct: 245 SGSLPFDGQNLKELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 301
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 76.6 bits (187), Expect = 1e-13
Identities = 68/254 (26%), Positives = 111/254 (42%), Gaps = 39/254 (15%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
V + + + S+ +R EV +KAL G++ +V + D + V+++ME
Sbjct: 174 VKIISKAKMTSTLSIEDVRREVKLLKALSGHRHMVKFYDVYEDAD-------NVFVVMEL 226
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
C GG L+D + R R E + I+ Q+ A H ++HRD+K EN L + +
Sbjct: 227 CEGGELLDRILAR-GGRYPEVDAKRILVQILSATAFFHL--QGVVHRDLKPENFLFTSRN 283
Query: 172 E---FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGLPIDE 225
E K+ DFG ++++YD N +A Y PE+ L+R +
Sbjct: 284 EDAILKVIDFGLS-------------DFIRYDQRLNDVVGSAYYVAPEV--LHRSYSTE- 327
Query: 226 KSDIWALGVFLYKTCYYTTPFEKNGESAILA------SKFEFPAYPRYSDRVKNLISVML 279
+D+W++GV Y + PF ESAI FE +P S K+ + +L
Sbjct: 328 -ADMWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFEDMPWPSISPTAKDFVKRLL 386
Query: 280 RVDPLKRPNICQVV 293
D KR Q +
Sbjct: 387 NKDHRKRMTAAQAL 400
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 76.6 bits (187), Expect = 1e-13
Identities = 84/307 (27%), Positives = 136/307 (43%), Gaps = 55/307 (17%)
Query: 2 NQPQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVP 61
+ P+ + Y +G G K++K L G FA V + I P +K +
Sbjct: 47 SSPKFQSYVNGN----GYGVYKIIKTLGKGNFAKV-KLAIHLPT----GREVAIKLI--- 94
Query: 62 DKASLNT-----LRAEVDSMKALRGNKFI--VSYIDSHATKSPVNVGMYEVYLLMEYCSG 114
DK +LNT L EV+ MK L + + I+S T +YL+MEY SG
Sbjct: 95 DKTALNTIARQKLYREVNIMKKLNHPNIVRLLQVIESERT----------LYLVMEYVSG 144
Query: 115 GGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFK 174
G L +++ R++E + + Q+ + H+ ++HRD+K EN+LL + + K
Sbjct: 145 GELFNYLVKN--GRMRERDARVLFRQLVSAIEYCHSKS--IVHRDLKAENLLLDQQMKLK 200
Query: 175 LCDFG-SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWAL 232
+ DFG S + +AP T + Y PE L+RG + D W+L
Sbjct: 201 IADFGFSTTFEPKAPLET-----------FCGSPPYAAPE---LFRGKKYSGPEVDSWSL 246
Query: 233 GVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPN 288
GV LY + PF+ K +L K+ P Y S ++LI L ++P +R +
Sbjct: 247 GVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRVPYY--VSIECESLIRKFLVLNPTQRTS 304
Query: 289 ICQVVEE 295
+ V+ +
Sbjct: 305 LSAVMAD 311
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 76.3 bits (186), Expect = 2e-13
Identities = 80/283 (28%), Positives = 124/283 (43%), Gaps = 43/283 (15%)
Query: 50 DNVACLKRVVVPDKASLNT------LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMY 103
DN V V KA + T +R EV ++AL G+ + + D++
Sbjct: 171 DNKGQQVAVKVIPKAKMTTAIAIEDVRREVKILRALSGHNNLPHFYDAYEDHD------- 223
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
VY++ME C GG L+D + +R + E + +M Q+ VA H ++HRD+K E
Sbjct: 224 NVYIVMELCEGGELLDRILSR-GGKYTEEDAKTVMIQILNVVAFCHL--QGVVHRDLKPE 280
Query: 164 NVLLSKNH---EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRG 220
N L + + K DFG V R E N DI+ +A Y PE+ L+R
Sbjct: 281 NFLFTSKEDTSQLKAIDFGLSDYV----RPDERLN----DIV--GSAYYVAPEV--LHRS 328
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNL 274
++DIW++GV +Y + PF ES I + F+ P +P S ++
Sbjct: 329 --YSTEADIWSVGVIVYILLCGSRPFWARTESGIFRAVLKADPSFDDPPWPLLSSEARDF 386
Query: 275 ISVMLRVDPLKRPNICQVVE----EVSRIQGIPCPIKNFYLLR 313
+ +L DP KR Q + + S +P I F L+R
Sbjct: 387 VKRLLNKDPRKRLTAAQALSHPWIKDSNDAKVPMDILVFKLMR 429
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 75.9 bits (185), Expect = 2e-13
Identities = 73/237 (30%), Positives = 115/237 (47%), Gaps = 34/237 (14%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNI-MSQVSQGVAAMHALQPPLIHRDIKIE 163
VY+++E+ GG D +N + N+L +I + Q+ V +H + HRD+K +
Sbjct: 236 VYMVLEFMRGG---DLLNRIISNKLLSEDISKLYFYQMCHAVKYLH--DRGITHRDLKPD 290
Query: 164 NVLLSKNHE---FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDL 217
NVLL N E K+ DFG +VQ D + T T Y PE++
Sbjct: 291 NVLLETNDEETLLKVSDFGLSK-------------FVQKDSVMRTLCGTPLYVAPEVLIT 337
Query: 218 YRGLPIDEKSDIWALGVFLYKTCYYTTPF-EKNGESA---ILASKFEF--PAYPRYSDRV 271
+K DIW+LGV L+ T PF ++ G A I +F + P++ S R
Sbjct: 338 GGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRA 397
Query: 272 KNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRM--MDKQEQPRVSPP 326
K LI+ ML VDP +RP+I V++ S ++ P K L+++ M+ +E+ + PP
Sbjct: 398 KLLINQMLIVDPERRPSIDDVLQS-SWLRDAPMLQKAKRLMKLDGMEIEEENFLEPP 453
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 75.5 bits (184), Expect = 3e-13
Identities = 57/195 (29%), Positives = 94/195 (47%), Gaps = 26/195 (13%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
Y+L EY SGG L+D++ L+E ++ + +HA ++HRD+KIEN+
Sbjct: 199 YMLFEYVSGGQLLDYIIQH--GSLKEHHARKFARGIASALQYLHANN--IVHRDLKIENI 254
Query: 166 LLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDL--YRGLPI 223
++S + E K+ DFG +S + + F Y + PE++ Y G +
Sbjct: 255 MISSSGEIKIIDFG-LSNIFDYRKQLHTFCGSLY---------FAAPELLKAQPYTGPEV 304
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEFPAYPRYSDRVKNLISVML 279
DIW+ G+ LY PF+ S I K ++P++ S V +L++ M+
Sbjct: 305 ----DIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSH--LSIEVISLLTRMI 358
Query: 280 RVDPLKRPNICQVVE 294
VDPL+R + VVE
Sbjct: 359 VVDPLRRATLKNVVE 373
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 75.5 bits (184), Expect = 3e-13
Identities = 82/257 (31%), Positives = 109/257 (41%), Gaps = 39/257 (15%)
Query: 51 NVAC---LKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYL 107
N AC LKR ++ K +R E+ M L G IV ++ + V+L
Sbjct: 123 NFACKSILKRKLIRTK-DREDVRREIQIMHYLSGQPNIVEIKGAYEDRQ-------SVHL 174
Query: 108 LMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLL 167
+ME C GG L D + R E I+ V + V H + +IHRD+K EN LL
Sbjct: 175 VMELCEGGELFDKITKR--GHYSEKAAAEIIRSVVKVVQICHFMG--VIHRDLKPENFLL 230
Query: 168 SKNHE----FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
S E K DFG VS I E V DI+ + A Y PE++ G I
Sbjct: 231 SSKDEASSMLKATDFG-VSVFI-------EEGKVYEDIVGS--AYYVAPEVLKRNYGKAI 280
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISV 277
D IW+ GV LY PF + I FE +P S+ K+L+
Sbjct: 281 D----IWSAGVILYILLCGNPPFWAETDKGIFEEILRGEIDFESEPWPSISESAKDLVRN 336
Query: 278 MLRVDPLKRPNICQVVE 294
ML+ DP KR QV+E
Sbjct: 337 MLKYDPKKRFTAAQVLE 353
>At1g18160 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 990
Score = 75.5 bits (184), Expect = 3e-13
Identities = 59/244 (24%), Positives = 113/244 (46%), Gaps = 33/244 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
+L R+EV M+ LR ++ A P N+ ++ E+ G L ++ R
Sbjct: 751 ALEEFRSEVRMMRRLRHPNIVLFM---GAVTRPPNLS-----IVTEFLPRGSLYRLIH-R 801
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
N+L E + L + ++G+ +H+ P ++HRD+K N+L+ KN K+CDFG
Sbjct: 802 PNNQLDERKRLRMALDAARGMNYLHSCNPVIVHRDLKSPNLLVDKNWVVKVCDFG----- 856
Query: 185 IRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYY 242
Y K+T TA++ PE++ R P DEK D+++ GV L++
Sbjct: 857 ------LSRMKVSTYLSSKSTAGTAEWMAPEVL---RNEPADEKCDVYSYGVILWELFTL 907
Query: 243 TTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV 296
P+ K ++ + + + P + + ++I + DP RP+ ++++ +
Sbjct: 908 QQPWGKMNPMQVVGAVGFQHRRLDIPEF--VDPGIADIIRKCWQTDPRLRPSFGEIMDSL 965
Query: 297 SRIQ 300
++Q
Sbjct: 966 KQLQ 969
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 75.1 bits (183), Expect = 4e-13
Identities = 70/275 (25%), Positives = 125/275 (45%), Gaps = 37/275 (13%)
Query: 28 LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVS 87
+ GGFA + V+ + + +A KR + DK L L E+ +++ + IV
Sbjct: 47 IGEGGFARCFRVKDNYGNIYAAKVIA--KRSLQNDKTKLK-LFGEIKVHQSM-SHPNIVG 102
Query: 88 YIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAA 147
+ID + +YL++E C L++ + R Q L E E+ +M Q+ +
Sbjct: 103 FIDCFEDST-------NIYLILELCEHKSLMELLRKRKQ--LTEPEVRYLMMQILGALKY 153
Query: 148 MHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEF----NYVQYDIMK 203
MH + +IHRD+K+ N++L +++ K+ DFG + ++ NY+ +I+
Sbjct: 154 MHKKR--VIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILF 211
Query: 204 NTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKF 259
N+ + + D+W+ GV +Y PF+ K I A+ +
Sbjct: 212 NSKEGH--------------SFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSY 257
Query: 260 EFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
FP+ S K+LIS +L DP RP+I +V+
Sbjct: 258 SFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIVD 292
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 75.1 bits (183), Expect = 4e-13
Identities = 68/249 (27%), Positives = 115/249 (45%), Gaps = 36/249 (14%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
V L R + + +R E+ ++ R + I+ +T S +++++ME+
Sbjct: 53 VKILNRQKIKSLDVVGKIRREIQNLSLFR-HPHIIRLYQVISTPS-------DIFMIMEH 104
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
SGG L D++ RL+ E Q+ GV H + ++HRD+K EN+LL + +
Sbjct: 105 VSGGELFDYIVKH--GRLKTAEARRFFQQIISGVDYCH--RHMVVHRDLKPENLLLDEQN 160
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMID--LYRGLPIDEKS 227
K+ DFG +S ++ D ++ + + Y PE+I LY G +
Sbjct: 161 NVKIADFG-LSNIM-----------TDGDFLRTSCGSPNYAAPEVISGKLYAGPEV---- 204
Query: 228 DIWALGVFLYKTCYYTTPFEKNGESAIL--ASKFEFPAYPRYSDR-VKNLISVMLRVDPL 284
D+W+ GV LY T PF+ ++ FP P + +R + NL+ ML VDP+
Sbjct: 205 DVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPT-PDFLERPIVNLLHHMLCVDPM 263
Query: 285 KRPNICQVV 293
KR I V+
Sbjct: 264 KRATIKDVI 272
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 75.1 bits (183), Expect = 4e-13
Identities = 73/280 (26%), Positives = 122/280 (43%), Gaps = 39/280 (13%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRV--VVPDKASLNTLRAEVDSMKALR 80
K+LK + G FA V + V + +K + + +SL L EV MK L
Sbjct: 123 KLLKTIGKGNFAKVKLAK-----HVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLD 177
Query: 81 GNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQ 140
+ Y ++ +YL++EY SGG + D++ R++E E Q
Sbjct: 178 HPNIVKLYQVMETEQT--------LYLVLEYASGGEVFDYLVAH--GRMKEKEARAKFRQ 227
Query: 141 VSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYD 200
+ V +H+ +IHRD+K EN+LL ++ K+ DFG S + F
Sbjct: 228 IVSAVQYLHSKN--IIHRDLKAENLLLDQDMNIKIADFG-FSNTFSLGNKLDTF------ 278
Query: 201 IMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTCYYTTPFE----KNGESAIL 255
+ Y PE L+ G D + D+W+LGV LY + PF+ K +L
Sbjct: 279 ---CGSPPYAAPE---LFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 332
Query: 256 ASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
K+ P Y S +NL+ L ++P +R ++ ++++
Sbjct: 333 RGKYRIPFY--MSTDCENLLKKFLVINPQRRSSLDNIMKD 370
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 75.1 bits (183), Expect = 4e-13
Identities = 73/280 (26%), Positives = 122/280 (43%), Gaps = 39/280 (13%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRV--VVPDKASLNTLRAEVDSMKALR 80
K+LK + G FA V + V + +K + + +SL L EV MK L
Sbjct: 171 KLLKTIGKGNFAKVKLAK-----HVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLD 225
Query: 81 GNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQ 140
+ Y ++ +YL++EY SGG + D++ R++E E Q
Sbjct: 226 HPNIVKLYQVMETEQT--------LYLVLEYASGGEVFDYLVAH--GRMKEKEARAKFRQ 275
Query: 141 VSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYD 200
+ V +H+ +IHRD+K EN+LL ++ K+ DFG S + F
Sbjct: 276 IVSAVQYLHSKN--IIHRDLKAENLLLDQDMNIKIADFG-FSNTFSLGNKLDTF------ 326
Query: 201 IMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTCYYTTPFE----KNGESAIL 255
+ Y PE L+ G D + D+W+LGV LY + PF+ K +L
Sbjct: 327 ---CGSPPYAAPE---LFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 380
Query: 256 ASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
K+ P Y S +NL+ L ++P +R ++ ++++
Sbjct: 381 RGKYRIPFY--MSTDCENLLKKFLVINPQRRSSLDNIMKD 418
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 75.1 bits (183), Expect = 4e-13
Identities = 68/249 (27%), Positives = 115/249 (45%), Gaps = 36/249 (14%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
V L R + + +R E+ ++ R + I+ +T S +++++ME+
Sbjct: 53 VKILNRQKIKSLDVVGKIRREIQNLSLFR-HPHIIRLYQVISTPS-------DIFMIMEH 104
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
SGG L D++ RL+ E Q+ GV H + ++HRD+K EN+LL + +
Sbjct: 105 VSGGELFDYIVKH--GRLKTAEARRFFQQIISGVDYCH--RHMVVHRDLKPENLLLDEQN 160
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMID--LYRGLPIDEKS 227
K+ DFG +S ++ D ++ + + Y PE+I LY G +
Sbjct: 161 NVKIADFG-LSNIM-----------TDGDFLRTSCGSPNYAAPEVISGKLYAGPEV---- 204
Query: 228 DIWALGVFLYKTCYYTTPFEKNGESAIL--ASKFEFPAYPRYSDR-VKNLISVMLRVDPL 284
D+W+ GV LY T PF+ ++ FP P + +R + NL+ ML VDP+
Sbjct: 205 DVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPT-PDFLERPIVNLLHHMLCVDPM 263
Query: 285 KRPNICQVV 293
KR I V+
Sbjct: 264 KRATIKDVI 272
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 75.1 bits (183), Expect = 4e-13
Identities = 71/275 (25%), Positives = 126/275 (45%), Gaps = 37/275 (13%)
Query: 28 LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVS 87
L +G F V+ V + +N A K V+ P ++ T+R E+ +M LR + +V+
Sbjct: 6269 LGTGAFGVVHRVT----ERATGNNFAA-KFVMTPHESDKETVRKEIQTMSVLR-HPTLVN 6322
Query: 88 YIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAA 147
D+ + E+ ++ E+ SGG L + + N++ E E + M QV +G+
Sbjct: 6323 LHDAFEDDN-------EMVMIYEFMSGGELFEKVADE-HNKMSEDEAVEYMRQVCKGLCH 6374
Query: 148 MHALQPPLIHRDIKIENVLLS--KNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
MH + +H D+K EN++ + +++E KL DFG T + Q +
Sbjct: 6375 MH--ENNYVHLDLKPENIMFTTKRSNELKLIDFGL----------TAHLDPKQSVKVTTG 6422
Query: 206 TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS------KF 259
TA++ PE+ + G P+ +D+W++GV Y +PF + L +
Sbjct: 6423 TAEFAAPEVAE---GKPVGYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKSCDWNM 6479
Query: 260 EFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
+ A+ S+ K+ I +L DP R I Q +E
Sbjct: 6480 DDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALE 6514
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 75.1 bits (183), Expect = 4e-13
Identities = 71/275 (25%), Positives = 126/275 (45%), Gaps = 37/275 (13%)
Query: 28 LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVS 87
L +G F V+ V + +N A K V+ P ++ T+R E+ +M LR + +V+
Sbjct: 5940 LGTGAFGVVHRVT----ERATGNNFAA-KFVMTPHESDKETVRKEIQTMSVLR-HPTLVN 5993
Query: 88 YIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAA 147
D+ + E+ ++ E+ SGG L + + N++ E E + M QV +G+
Sbjct: 5994 LHDAFEDDN-------EMVMIYEFMSGGELFEKVADE-HNKMSEDEAVEYMRQVCKGLCH 6045
Query: 148 MHALQPPLIHRDIKIENVLLS--KNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
MH + +H D+K EN++ + +++E KL DFG T + Q +
Sbjct: 6046 MH--ENNYVHLDLKPENIMFTTKRSNELKLIDFGL----------TAHLDPKQSVKVTTG 6093
Query: 206 TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS------KF 259
TA++ PE+ + G P+ +D+W++GV Y +PF + L +
Sbjct: 6094 TAEFAAPEVAE---GKPVGYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKSCDWNM 6150
Query: 260 EFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
+ A+ S+ K+ I +L DP R I Q +E
Sbjct: 6151 DDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALE 6185
>At3g04810 [R] KOG0589 Serine/threonine protein kinase
Length = 606
Score = 75.1 bits (183), Expect = 4e-13
Identities = 58/219 (26%), Positives = 104/219 (47%), Gaps = 28/219 (12%)
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
N FIV Y DS K G Y V +++ YC GG + + + E ++ + Q+
Sbjct: 60 NPFIVEYKDSWVEK-----GCY-VCIIIGYCKGGDMAEAIKKTNGVHFTEEKLCKWLVQI 113
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDI 201
+ +HA ++HRD+K N+ L+K+ + +L DFG ++ V+ + D+
Sbjct: 114 LLALEYLHANH--ILHRDVKCSNIFLTKDQDIRLGDFG-LAKVLTSD-----------DL 159
Query: 202 MKNT--TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL--AS 257
+ T Y CPE++ +P KSDIW+LG +Y+ F+ ++ +
Sbjct: 160 ASSVVGTPSYMCPELL---ADIPYGSKSDIWSLGCCMYEMTAMKPAFKAFDMQGLINRIN 216
Query: 258 KFEFPAYP-RYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ P P +YS + L+ MLR +P RP+ +++ +
Sbjct: 217 RSIVPPLPAQYSAAFRGLVKSMLRKNPELRPSAAELLRQ 255
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 74.7 bits (182), Expect = 5e-13
Identities = 60/196 (30%), Positives = 91/196 (45%), Gaps = 17/196 (8%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+Y L+EY G + + + L E SQ+ V ++H + +IHRDIK EN
Sbjct: 199 LYFLLEYAPHGDFLGLI--KKYGSLNETCARYYASQIIDAVDSLHNIG--IIHRDIKPEN 254
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT-----TAQYRCPEMI-DLY 218
+LL KN + KL DFG+ + P NT + +D+ + TA+Y PE++ D Y
Sbjct: 255 ILLDKNMKVKLTDFGTAKILPEEPSNTAD-GKPYFDLYAKSKSFVGTAEYVSPELLNDNY 313
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL--ASKFEFPAYPRYSDRVKNLIS 276
D + DIWA G LY+ PF+ E K ++ + VK+L+
Sbjct: 314 ----TDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVK 369
Query: 277 VMLRVDPLKRPNICQV 292
+L DP R I Q+
Sbjct: 370 KLLVRDPNDRLTIKQI 385
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 74.7 bits (182), Expect = 5e-13
Identities = 67/248 (27%), Positives = 111/248 (44%), Gaps = 34/248 (13%)
Query: 52 VACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY 111
+ L R + ++N R E+D+++ L + I +T S +++L+ME
Sbjct: 52 IKILNRGRMKGLGTVNKTRNEIDNLQKLT-HPHITRLFRVISTPS-------DIFLVMEL 103
Query: 112 CSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNH 171
SGG L ++ + L E Q+ GV+ H ++HRD+K EN+LL N
Sbjct: 104 VSGGELFSYITRK--GALPIRESRRYFQQIISGVSYCH--NHMIVHRDLKPENLLLDANK 159
Query: 172 EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGLPIDEKSD 228
K+ DFG NY+ + +T + Y PE+I L + + D
Sbjct: 160 NIKIADFGL-------------SNYMTDGDLLSTACGSPNYAAPELIS--NKLYVGPEVD 204
Query: 229 IWALGVFLYKTCYYTTPFEKNGESAILASKFEFPAYP---RYSDRVKNLISVMLRVDPLK 285
+W+ GV LY T PF+ + A K + Y + +LIS ML+VDP+K
Sbjct: 205 LWSCGVILYAMLCGTLPFDDQNVPTLFA-KIKSGRYTVPYSMEKQAADLISTMLQVDPVK 263
Query: 286 RPNICQVV 293
R ++ ++V
Sbjct: 264 RADVKRIV 271
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 74.7 bits (182), Expect = 5e-13
Identities = 59/229 (25%), Positives = 107/229 (45%), Gaps = 29/229 (12%)
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
E++ + +R N FIV Y DS K G Y V +++ YC GG + + + E
Sbjct: 51 EMELISKIR-NPFIVEYKDSWVEK-----GCY-VCIVIGYCKGGDMAEAIKKANGVEFSE 103
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
++ + Q+ + +HA ++HRD+K N+ L+K+ + +L DFG ++ ++ +
Sbjct: 104 EKLCKWLVQLLMALEYLHASH--ILHRDVKCSNIFLTKDQDIRLGDFG-LAKILTSD--- 157
Query: 192 EEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYT---TPF 246
D+ + T Y CPE++ +P KSDIW+LG +Y+ F
Sbjct: 158 --------DLASSVVGTPSYMCPELL---ADIPYGSKSDIWSLGCCMYEMTALKPAFKAF 206
Query: 247 EKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ G + P +YS ++L+ MLR +P RP+ ++ +
Sbjct: 207 DMQGLINRINRSIVAPLPAQYSTAFRSLVKSMLRKNPELRPSASDLLRQ 255
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 74.7 bits (182), Expect = 5e-13
Identities = 71/232 (30%), Positives = 107/232 (45%), Gaps = 39/232 (16%)
Query: 107 LLMEYCSGGGLIDFMNTRLQN--RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++MEY SGG L + R+ N R E E Q+ GV+ HA+Q + HRD+K+EN
Sbjct: 92 IVMEYASGGELFE----RICNAGRFSEDEARFFFQQLISGVSYCHAMQ--VCHRDLKLEN 145
Query: 165 VLL--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLY 218
LL S K+CDFG S S V+ + P++T T Y PE++ Y
Sbjct: 146 TLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVG------------TPAYIAPEVLLKKEY 193
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA--------ILASKFEFPAYPRYSDR 270
G + +D+W+ GV LY PFE E IL ++ P Y S
Sbjct: 194 DG----KVADVWSCGVTLYVMLVGAYPFEDPEEPKNFRKTIHRILNVQYAIPDYVHISPE 249
Query: 271 VKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKN-FYLLRMMDKQEQP 321
++LIS + DP KR +I ++ ++ +P + N + D+ +QP
Sbjct: 250 CRHLISRIFVADPAKRISIPEIRNHEWFLKNLPADLMNDNTMTTQFDESDQP 301
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 74.7 bits (182), Expect = 5e-13
Identities = 78/298 (26%), Positives = 134/298 (44%), Gaps = 33/298 (11%)
Query: 3 QPQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPD 62
QPQ + + T + + ++ + L SG FA V+ D + + K+ + +
Sbjct: 6 QPQNQSSPATTPAKILLGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTI--E 63
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
+ E+D+M+ LR + I+ + ATKS ++YL+ME SGG L F
Sbjct: 64 SGMEPRIIREIDAMRRLRHHPNILKIHEVMATKS-------KIYLVMELASGGEL--FSK 114
Query: 123 TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVS 182
+ RL E Q++ + H Q + HRD+K +N+LL + K+ DF
Sbjct: 115 VLRRGRLPESTARRYFQQLASALRFSH--QDGVAHRDVKPQNLLLDEQGNLKVSDF---- 168
Query: 183 GVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTC 240
G+ P ++Q ++ T Y PE+I RG K+D W+ GV L+
Sbjct: 169 GLSALP------EHLQNGLLHTACGTPAYTAPEVIS-RRGYD-GAKADAWSCGVILFVLL 220
Query: 241 YYTTPFEKNGESA----ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
PF+ + +A I + FP++ S + K++I ML +P+ R +I V++
Sbjct: 221 VGDVPFDDSNIAAMYRKIHRRDYRFPSW--ISKQAKSIIYQMLDPNPVTRMSIETVMK 276
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 74.7 bits (182), Expect = 5e-13
Identities = 71/254 (27%), Positives = 119/254 (45%), Gaps = 33/254 (12%)
Query: 49 PDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLL 108
P V + + + ++ +R EV +K+L G+K+++ Y D+ + VY++
Sbjct: 171 PIAVKIISKAKMTTAIAIEDVRREVKLLKSLSGHKYLIKYYDACEDAN-------NVYIV 223
Query: 109 MEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS 168
ME C GG L+D + R + E + I+ Q+ V+ H ++HRD+K EN L +
Sbjct: 224 MELCDGGELLDRILAR-GGKYPEDDAKAIVVQILTVVSFCHL--QGVVHRDLKPENFLFT 280
Query: 169 KNHE---FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDE 225
+ E KL DFG +S IR E N DI+ +A Y PE+ L+R ++
Sbjct: 281 SSREDSDLKLIDFG-LSDFIRP---DERLN----DIV--GSAYYVAPEV--LHRSYSLE- 327
Query: 226 KSDIWALGVFLYKTCYYTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVML 279
+DIW++GV Y + PF ES I + ++ +P S K+ + +L
Sbjct: 328 -ADIWSIGVITYILLCGSRPFWARTESGIFRTVLRTEPNYDDVPWPSCSSEGKDFVKRLL 386
Query: 280 RVDPLKRPNICQVV 293
D KR + Q +
Sbjct: 387 NKDYRKRMSAVQAL 400
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 74.7 bits (182), Expect = 5e-13
Identities = 80/263 (30%), Positives = 115/263 (43%), Gaps = 36/263 (13%)
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
+ + +R EV ++ L G IV + ++ K ++L+ME CSGG L D +
Sbjct: 124 RKDIEDVRREVMILQHLTGQPNIVEFRGAYEDKD-------NLHLVMELCSGGELFDRII 176
Query: 123 TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFG 179
+ E E NI Q+ V H + ++HRD+K EN LL N E K DFG
Sbjct: 177 KK--GSYSEKEAANIFRQIVNVVHVCHFMG--VVHRDLKPENFLLVSNEEDSPIKATDFG 232
Query: 180 SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
+ E V DI+ +A Y PE++ G I D+W+ GV LY
Sbjct: 233 LSVFI--------EEGKVYRDIV--GSAYYVAPEVLHRNYGKEI----DVWSAGVMLYIL 278
Query: 240 CYYTTPF----EKNGESAILASK--FEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
PF EK AIL K E +P S+ K+LI ML DP KR + +
Sbjct: 279 LSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEAL 338
Query: 294 EE--VSRIQGIPCPIKNFYLLRM 314
E ++ + PI + L+RM
Sbjct: 339 EHPWMTDTKISDKPINSAVLVRM 361
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 74.3 bits (181), Expect = 7e-13
Identities = 58/191 (30%), Positives = 92/191 (47%), Gaps = 24/191 (12%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++++MEYC GG D + N L E ++ I+ +V+ G+ +H + IHRDIK N
Sbjct: 89 MWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLH--EQRKIHRDIKAAN 146
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID 224
+LL++ KL DFG VSG IR+ + F Y + C E +D Y +
Sbjct: 147 ILLNEEGMVKLGDFG-VSGHIRSTLKRDTFVGTPYWMAPEVV----CCE-VDGY-----N 195
Query: 225 EKSDIWALGVFLYKTCYYTTPFEKNGESAILAS-------KFEFPAYPRYSDRVKNLISV 277
EK+DIW+LG+ Y+ P K ++ + K + P +SD K+ ++
Sbjct: 196 EKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP----FSDAAKDFVAG 251
Query: 278 MLRVDPLKRPN 288
L P RP+
Sbjct: 252 CLVKTPADRPS 262
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 74.3 bits (181), Expect = 7e-13
Identities = 59/195 (30%), Positives = 92/195 (46%), Gaps = 24/195 (12%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
++YL++EY GG + + + R E M +++ ++ H + +IHRDIK E
Sbjct: 102 KIYLVLEYAPGGEM--YKQLTVSKRFSEPTAAKYMYEIADALSYCH--RKNVIHRDIKPE 157
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
N+L+ E K+ DFG + AP N + T Y PEM++ G
Sbjct: 158 NLLIGSQGELKIGDFG---WSVHAPSNKRQ--------TMCGTMDYLPPEMVN---GADH 203
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEFPAYPRYSDRVKNLISVML 279
+ D+WA+GV Y+ PFE +S AI A++F +P + R +LI +L
Sbjct: 204 SDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGAR--DLIGRLL 261
Query: 280 RVDPLKRPNICQVVE 294
VDP R + QV E
Sbjct: 262 VVDPKARCTLEQVKE 276
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 74.3 bits (181), Expect = 7e-13
Identities = 57/194 (29%), Positives = 99/194 (50%), Gaps = 20/194 (10%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
+++MEYCSGG + D++ + RL+E E + Q+ +A +H+ HRD+K EN+
Sbjct: 83 FIVMEYCSGGEMFDYIVRK--ERLEESEARHFFRQLVSAIAFVHS--QGYAHRDLKPENL 138
Query: 166 LLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPI 223
LL+++ KL DFG + A + D + A Y PE+I Y+G
Sbjct: 139 LLTEDLHLKLIDFG-----LCAKTEKGRIDKHNLDTCCGSPA-YAAPELIQGLQYKG--- 189
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFEFPAY--PRY-SDRVKNLISVMLR 280
++D+W++G+ LY PFE + I+ K + + P + S K L+ ML+
Sbjct: 190 -NEADVWSMGILLYTLLVGALPFE-DDNMQIMYKKIQSGCFYEPEFLSPLSKQLLRAMLQ 247
Query: 281 VDPLKRPNICQVVE 294
V P +R ++ +++E
Sbjct: 248 VVPERRISVKKLLE 261
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 74.3 bits (181), Expect = 7e-13
Identities = 60/197 (30%), Positives = 91/197 (45%), Gaps = 31/197 (15%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
++Y++MEY G L D++ + +LQE E ++ Q+ GV H + ++HRD+K E
Sbjct: 91 DIYVVMEYVKSGELFDYIVEK--GKLQEDEARHLFQQIISGVEYCH--RNMIVHRDLKPE 146
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYD--IMKNT--TAQYRCPEMIDLYR 219
NVLL K+ DFG + V +D +K + + Y PE+I
Sbjct: 147 NVLLDSQCNIKIVDFG--------------LSNVMHDGHFLKTSCGSPNYAAPEVIS--- 189
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLI 275
G P DIW+ GV LY T PF+ N I + P + S ++LI
Sbjct: 190 GKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNH--LSHFARDLI 247
Query: 276 SVMLRVDPLKRPNICQV 292
ML VDP R +I ++
Sbjct: 248 PRMLMVDPTMRISITEI 264
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 74.3 bits (181), Expect = 7e-13
Identities = 66/211 (31%), Positives = 98/211 (46%), Gaps = 34/211 (16%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL 166
L+MEY +GG L F R E E Q+ GV H+LQ + HRD+K+EN L
Sbjct: 75 LVMEYAAGGEL--FGRICSAGRFSEDEARFFFQQLISGVNYCHSLQ--ICHRDLKLENTL 130
Query: 167 L--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDL--YRG 220
L S+ K+CDFG S SGV+ + P+ T T Y PE++ Y G
Sbjct: 131 LDGSEAPRVKICDFGYSKSGVLHSQPKTTV------------GTPAYIAPEVLSTKEYDG 178
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGE--------SAILASKFEFPAYPRYSDRVK 272
+ +D+W+ GV LY PFE + IL +++ P Y R SD +
Sbjct: 179 ----KIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDYVRVSDECR 234
Query: 273 NLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
+L+S + +P KR I ++ ++ +P
Sbjct: 235 HLLSRIFVANPEKRITIEEIKNHSWFLKNLP 265
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 74.3 bits (181), Expect = 7e-13
Identities = 59/210 (28%), Positives = 96/210 (45%), Gaps = 27/210 (12%)
Query: 25 LKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKF 84
L L G + VY D + VA + + +R E++ ++ +
Sbjct: 252 LNELGKGSYGSVYKAR----DLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCN-HPN 306
Query: 85 IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQG 144
+V Y+ S+ G ++++MEYC GG + D MN + L+E++I I + +G
Sbjct: 307 VVRYLGSYQ-------GEDYLWIVMEYCGGGSVADLMNVT-EEALEEYQIAYICREALKG 358
Query: 145 VAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKN 204
+A +H++ +HRDIK N+LL++ E KL DFG + + R F
Sbjct: 359 LAYLHSIYK--VHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTF---------I 407
Query: 205 TTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
T + PE+I R D K D+WALGV
Sbjct: 408 GTPHWMAPEVIQENR---YDGKVDVWALGV 434
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 74.3 bits (181), Expect = 7e-13
Identities = 68/238 (28%), Positives = 111/238 (46%), Gaps = 33/238 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
++ +R EV ++AL G+K +V + D+ + VY+ ME C GG L+D + R
Sbjct: 194 AIEDVRREVKILQALSGHKNLVQFYDAFEDNA-------NVYIAMELCEGGELLDRILAR 246
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS---KNHEFKLCDFGSV 181
+ E + ++ Q+ VA H ++HRD+K EN L + +N + K DFG
Sbjct: 247 -GGKYSENDAKPVIIQILNVVAFCHF--QGVVHRDLKPENFLYTSKEENSQLKAIDFGLS 303
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
V R E N DI+ +A Y PE+ L+R + +D+W++GV Y
Sbjct: 304 DFV----RPDERLN----DIV--GSAYYVAPEV--LHRSYTTE--ADVWSIGVIAYILLC 349
Query: 242 YTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+ PF ES I + F+ P +P S K+ + +L DP +R + Q +
Sbjct: 350 GSRPFWARTESGIFRAVLKADPSFDEPPWPFLSSDAKDFVKRLLFKDPRRRMSASQAL 407
>CE27894_1 [R] KOG0589 Serine/threonine protein kinase
Length = 1011
Score = 74.3 bits (181), Expect = 7e-13
Identities = 71/285 (24%), Positives = 128/285 (44%), Gaps = 36/285 (12%)
Query: 21 QVKVLKYLASGGFAHVYSV-EISPPDPVCPDNVACLKRVVVPD------KASLNTLRAEV 73
+ ++L L +G F VY+V + + P + LK + + + S + +EV
Sbjct: 430 EYELLDQLGAGAFGCVYTVRKKAQSHSENPAKLLALKEIFMTNLNDRESDKSFGDMISEV 489
Query: 74 DSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFE 133
+K + IV Y + V + +Y++M+ G L D + T ++ + FE
Sbjct: 490 KIIKQQLRHPNIVRY-------RRIFVENHRLYIVMDLIQGCSLRDLIIT-MKEKKGNFE 541
Query: 134 ILNIMSQVSQGVAAMHAL--QPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
I + V Q + A+ L + ++HRD+K N++++ + + DFG + P
Sbjct: 542 EKKIWAMVVQMMLALRYLHKEKQIVHRDLKPNNIMMTTDERVVITDFGLAKQ--KGP--- 596
Query: 192 EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNG- 250
+Y T Y CPE++ + LP EK+DIW+ G +Y+ C F
Sbjct: 597 ------EYLKSAAGTIIYSCPEIV---QNLPYGEKADIWSFGCCIYEMCQLQPVFHSTNM 647
Query: 251 ---ESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
I+ +K++ P +SD ++ LI+ L DP RP+I +V
Sbjct: 648 LTLAMQIVEAKYD-PLNEMWSDDLRFLITSCLAPDPSARPDILKV 691
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 73.9 bits (180), Expect = 9e-13
Identities = 68/229 (29%), Positives = 109/229 (46%), Gaps = 30/229 (13%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSH-ATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQN 127
LR EV+ LR + Y H AT+ VYL++EY G + + + +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATR---------VYLILEYAPLGTV--YRELQKLS 226
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
+ E +++++ ++ H+ + +IHRDIK EN+LL E K+ DFG + A
Sbjct: 227 KFDEQRTATYITELANALSYCHSKR--VIHRDIKPENLLLGSAGELKIADFG---WSVHA 281
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFE 247
P + T Y PEMI+ G DEK D+W+LGV Y+ PFE
Sbjct: 282 PSSRR--------TTLCGTLDYLPPEMIE---GRMHDEKVDLWSLGVLCYEFLVGKPPFE 330
Query: 248 KN--GESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
N E+ S+ EF ++ ++LIS +L+ +P +RP + +V+E
Sbjct: 331 ANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLE 379
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 73.9 bits (180), Expect = 9e-13
Identities = 76/272 (27%), Positives = 111/272 (39%), Gaps = 36/272 (13%)
Query: 28 LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASL-NTLRAEVDSMKALRGNKFIV 86
L G F +VY + + V ++ +K L + LR E++ L+ +
Sbjct: 15 LGKGKFGNVYLARLKESHFIVALKVLFKSQI---EKEGLEHQLRREIEIQAHLQHPNILR 71
Query: 87 SYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVA 146
Y H + VYL++EY G L + + +L E I+ +V+ +
Sbjct: 72 LYNYFHDAR--------RVYLILEYAPRGEL--YKELQKSEKLDEQRTATIIEEVADALT 121
Query: 147 AMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTT 206
H +IHRDIK EN+LL E K+ DFG R T T
Sbjct: 122 YCH--DKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKT-----------MCGT 168
Query: 207 AQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEFP 262
Y PEMI+ G DEK D+W +GV Y+ PFE S IL FP
Sbjct: 169 LDYLPPEMIE---GRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFP 225
Query: 263 AYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
R +LIS +LR PL+R + Q+++
Sbjct: 226 LSMPLGAR--DLISRLLRYQPLERLPLAQILK 255
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 73.9 bits (180), Expect = 9e-13
Identities = 65/202 (32%), Positives = 97/202 (47%), Gaps = 38/202 (18%)
Query: 107 LLMEYCSGGGLIDFMNTRLQN--RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++MEY +GG L + R+ N R E E Q+ GV+ HA+Q + HRD+K+EN
Sbjct: 75 IVMEYAAGGELFE----RICNAGRFSEDEGRYYFKQLISGVSYCHAMQ--ICHRDLKLEN 128
Query: 165 VLL--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDL--Y 218
LL S + K+CDFG S S V+ + P++T T Y PE++ Y
Sbjct: 129 TLLDGSPSSHLKICDFGYSKSSVLHSQPKSTVG------------TPAYVAPEVLSRKEY 176
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFE--------KNGESAILASKFEFPAYPRYSDR 270
G + +D+W+ GV LY PFE +N IL+ + P Y R S
Sbjct: 177 NG----KIADVWSCGVTLYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTIPDYVRISSE 232
Query: 271 VKNLISVMLRVDPLKRPNICQV 292
K+L+S + DP KR + ++
Sbjct: 233 CKHLLSRIFVADPDKRITVPEI 254
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 73.9 bits (180), Expect = 9e-13
Identities = 50/168 (29%), Positives = 86/168 (50%), Gaps = 14/168 (8%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E++ +K ++ I +Y + KSP +++L+MEYC G + D + +
Sbjct: 73 IKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDD-QLWLVMEYCGAGSVTDLVKSTKGQS 131
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L+E I I ++ +G++ +H+ + +IHRDIK +NVLL+ N E KL DFG + + R
Sbjct: 132 LKEEWIAYICREILRGLSYLHSNK--VIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTI 189
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
F Y + PE+I D D +SD+W+LG+
Sbjct: 190 GRRNTFIGTPY---------WMAPEVIACDENPDATYDNRSDLWSLGI 228
>7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1726
Score = 73.9 bits (180), Expect = 9e-13
Identities = 68/273 (24%), Positives = 113/273 (40%), Gaps = 44/273 (16%)
Query: 28 LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVS 87
L G F VY + A K + D+ +L+ E+D + ++ +
Sbjct: 43 LGDGAFGKVYKAQHKEQK-----RFAAAKMCQLEDEENLSDHMVEIDILSEIKHPNIVEL 97
Query: 88 Y----IDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQ 143
Y ID ++++L+EYC GG L D + L+ L E +I + +++
Sbjct: 98 YEAFSIDD------------KLWMLIEYCDGGAL-DSIMVELEKPLTEPQIAYVCKHMTE 144
Query: 144 GVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMK 203
G+ +H + +IHRD+K NVLL+ KL DFG + + + F Y
Sbjct: 145 GLTFLH--RNKVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPY---- 198
Query: 204 NTTAQYRCPEMI--DLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS---- 257
+ PE++ + +R P D K DIW+LG+ L + P + +L
Sbjct: 199 -----WMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKS 253
Query: 258 ---KFEFPAYPRYSDRVKNLISVMLRVDPLKRP 287
K E P+ R+S + + L DP RP
Sbjct: 254 EPPKLEQPS--RWSKEFNDFLKKSLVKDPQVRP 284
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 73.6 bits (179), Expect = 1e-12
Identities = 58/195 (29%), Positives = 92/195 (46%), Gaps = 28/195 (14%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+YLL+E+ SGG L D++ + RL E Q+ + HA + HRD+K EN
Sbjct: 119 LYLLLEHVSGGELFDYLVRK--GRLMSKEARKFFRQIISALDFCHAHN--ICHRDLKPEN 174
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLP 222
+LL + + K+ DFG S V+ +++ + + Y CPE+I RG
Sbjct: 175 LLLDERNNIKVADFGMAS------------LQVEGSMLETSCGSPHYACPEVI---RGEK 219
Query: 223 ID-EKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISV 277
D K+D+W+ GV LY PF+ +N + F P + V++L+
Sbjct: 220 YDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHF--VPADVQSLLRA 277
Query: 278 MLRVDPLKRPNICQV 292
M+ VDP KR ++ V
Sbjct: 278 MIEVDPGKRYSLADV 292
>7302458 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 596
Score = 73.6 bits (179), Expect = 1e-12
Identities = 76/301 (25%), Positives = 133/301 (43%), Gaps = 47/301 (15%)
Query: 5 QIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKA 64
+++K + ++L ++ L G + VY V ++ + + +VP ++
Sbjct: 25 KLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKA-------VHKESSSIVAIKLVPVES 77
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
L+ + E+ M+ + ++V Y S+ + Y++++ MEYC G + D M R
Sbjct: 78 DLHEIIKEISIMQQC-DSPYVVRYYGSYFKQ-------YDLWICMEYCGAGSVSDIMRLR 129
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
+ L E EI I+S QG+ +H + IHRDIK N+LL+ KL DFG V+G
Sbjct: 130 -KKTLTEDEIATILSDTLQGLVYLHLRRK--IHRDIKAANILLNTEGYAKLADFG-VAGQ 185
Query: 185 I---RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
+ A RNT T + PE+I+ + D +DIW+LG+ +
Sbjct: 186 LTDTMAKRNT-----------VIGTPFWMAPEVIE---EIGYDCVADIWSLGITALEMAE 231
Query: 242 YTTPFEKNGESAILASKFEFPAYP--------RYSDRVKNLISVMLRVDPLKRPNICQVV 293
P+ GE + + F P P R+S + +S L +P R +++
Sbjct: 232 GKPPY---GEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELL 288
Query: 294 E 294
E
Sbjct: 289 E 289
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 73.2 bits (178), Expect = 1e-12
Identities = 76/272 (27%), Positives = 111/272 (39%), Gaps = 35/272 (12%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNT-LRAEVDSMKALRGNKF 84
K L G F VY V +C V + ++ K +L R EV+ +L
Sbjct: 108 KKLGKGKFGKVYCVRHRSTGYICALKVMEKEEII---KYNLQKQFRREVEIQTSLNHPNL 164
Query: 85 IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQG 144
SY H K VYLLMEY G + + RL + + + Q++
Sbjct: 165 TKSYGYFHDEK--------RVYLLMEYLVNGEMYKLL--RLHGPFNDILASDYIYQIANA 214
Query: 145 VAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKN 204
+ MH + +IHRDIK EN+L+ N+ KL DFG +I P N +
Sbjct: 215 LDYMH--KKNIIHRDIKPENILIGFNNVIKLTDFG--WSIINPPENRRK--------TVC 262
Query: 205 TTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA----ILASKFE 260
T Y PEM++ D D WALGV ++ PFE+ + I A +
Sbjct: 263 GTIDYLSPEMVE---SREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIK 319
Query: 261 FPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
P+ S ++LI +L+ DP R + V
Sbjct: 320 MPS--NISQDAQDLILKLLKYDPKDRMRLGDV 349
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 73.2 bits (178), Expect = 1e-12
Identities = 68/238 (28%), Positives = 106/238 (43%), Gaps = 37/238 (15%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+YL++EY G L + + L E E +N Q+ G++ HAL ++HRD+K EN
Sbjct: 102 LYLILEYAEKGELFNLLVDH--GPLPEREAINCFRQIIIGISYCHALG--IVHRDLKPEN 157
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLP 222
+LL + K+ DFG + A D+++ + + Y PE++ GLP
Sbjct: 158 LLLDSFYNIKIADFGMAALQTDA------------DLLETSCGSPHYAAPEIVS---GLP 202
Query: 223 IDE-KSDIWALGVFLYKTCYYTTPF-EKNGESAILASK-----FEFPAYPRYSDRVKNLI 275
+ SD+W+ GV L+ PF E+NG L K FE P S ++LI
Sbjct: 203 YEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLI 262
Query: 276 SVMLRVDPLKRPNICQVVEE--VSRIQGI-------PCPIKNFYLLRMMDKQEQPRVS 324
+L VDP +R I ++ + + Q I P +N YL + D S
Sbjct: 263 GKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSAS 320
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 73.2 bits (178), Expect = 1e-12
Identities = 59/192 (30%), Positives = 93/192 (47%), Gaps = 18/192 (9%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+YL MEYC G L D++ + RL E IM Q+ + +H + +HRD+K+EN
Sbjct: 98 IYLAMEYCPNGELYDWVAR--EKRLDEKTTCRIMWQLCCAIQYLH--RQGCVHRDLKLEN 153
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID 224
+ L K + KL DFG S R T + + T Y PE++ ++ I
Sbjct: 154 IFLDKAYNVKLGDFG-FSRDSDCSRRT-------FMNTRCGTVAYCAPELVQGHK--YIG 203
Query: 225 EKSDIWALGVFLYKTCYYTTPFEKNGESAILASKF--EFPAYPR-YSDRVKNLISVMLRV 281
E DIW+LG+ +Y PF+++ + ++ K E P YP S +L+ +L
Sbjct: 204 ECVDIWSLGIIMYALLIGRLPFDED-DVSLTEQKIINECPQYPETLSKNSSSLLKSLLCK 262
Query: 282 DPLKRPNICQVV 293
D RP+I Q++
Sbjct: 263 DYRLRPSIDQII 274
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 73.2 bits (178), Expect = 1e-12
Identities = 72/249 (28%), Positives = 112/249 (44%), Gaps = 39/249 (15%)
Query: 56 KRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGG 115
KR +V +K + +R EV M L G IV ++ K + V+L+ME C+GG
Sbjct: 106 KRKLV-NKEDIEDVRREVQIMHHLTGQPNIVELKGAYEDK-------HSVHLVMELCAGG 157
Query: 116 GLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLL---SKNHE 172
L D + + E +++ + Q V H++ +IHRD+K EN LL +N
Sbjct: 158 ELFDRIIAK--GHYSERAAASLLRTIVQIVHTCHSMG--VIHRDLKPENFLLLNKDENSP 213
Query: 173 FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIW 230
K DFG Y ++ K+ +A Y PE++ G ++DIW
Sbjct: 214 LKATDFGL------------SVFYKPGEVFKDIVGSAYYIAPEVLKRKYG----PEADIW 257
Query: 231 ALGVFLYKTCYYTTPFEKNGE----SAILASKFEFPA--YPRYSDRVKNLISVMLRVDPL 284
++GV LY PF E +AIL +F + +P S + K+L+ ML DP
Sbjct: 258 SIGVMLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDLVKKMLNSDPK 317
Query: 285 KRPNICQVV 293
+R QV+
Sbjct: 318 QRLTAAQVL 326
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 73.2 bits (178), Expect = 1e-12
Identities = 68/241 (28%), Positives = 104/241 (42%), Gaps = 39/241 (16%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
S+ +R EV +KAL G+ +V + D V+++ME C GG L+D + R
Sbjct: 186 SIEDVRREVKLLKALSGHSHMVKFYDVFEDSD-------NVFVVMELCEGGELLDSILAR 238
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSV 181
R E E I+ Q+ A H ++HRD+K EN L + +E K+ DFG
Sbjct: 239 -GGRYPEAEAKRILVQILSATAFFHL--QGVVHRDLKPENFLFTSKNEDAVLKVIDFGLS 295
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYK 238
+Y ++D N +A Y PE+ L+R + +DIW++GV Y
Sbjct: 296 -------------DYARFDQRLNDVVGSAYYVAPEV--LHRSYSTE--ADIWSIGVISYI 338
Query: 239 TCYYTTPFEKNGESAILA------SKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
+ PF ESAI F+ +P S K+ + +L D KR Q
Sbjct: 339 LLCGSRPFYGRTESAIFRCVLRANPNFDDLPWPSISPIAKDFVKRLLNKDHRKRMTAAQA 398
Query: 293 V 293
+
Sbjct: 399 L 399
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 73.2 bits (178), Expect = 1e-12
Identities = 74/272 (27%), Positives = 115/272 (42%), Gaps = 35/272 (12%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
K++K + G FA V + P + ++ + SL L EV MK L
Sbjct: 152 KLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL---NPGSLQKLFREVRIMKMLDHP 208
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
+ + K+ +YL+MEY SGG + D++ L R++E E Q+
Sbjct: 209 NIVKLFQVIETEKT--------LYLIMEYASGGEVFDYLV--LHGRMKEKEARVKFRQIV 258
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
V H Q +IHRD+K EN+LL K+ DFG + EF
Sbjct: 259 SAVQYCH--QKRIIHRDLKAENLLLDSELNIKIADFGF----------SNEFTPGSKLDT 306
Query: 203 KNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTCYYTTPFE----KNGESAILAS 257
+ Y PE L++G D + D+W+LGV LY + PF+ + +L
Sbjct: 307 FCGSPPYAAPE---LFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRG 363
Query: 258 KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNI 289
K+ P Y S +NL+ L ++P KR ++
Sbjct: 364 KYRIPFY--MSTDCENLLRKFLVLNPAKRASL 393
>7300288 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 630
Score = 73.2 bits (178), Expect = 1e-12
Identities = 76/308 (24%), Positives = 130/308 (41%), Gaps = 35/308 (11%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRV-VVPD 62
P+ + + IL + +H+ + K L GG + V+ S N LK V + D
Sbjct: 319 PEQPSHKTSNILKIKNHEYTIDKKLGCGGSSSVFLARRSDSG-----NEFALKVVDLQAD 373
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEY--CSGGGLIDF 120
+ E + L+GN +V+ D + ++Y++ME C ++
Sbjct: 374 PQVVQGYLNETKLLAKLQGNVCVVALYDYQLVREES-----KLYMVMEKGDCDLNKILQS 428
Query: 121 MNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGS 180
T L + ++NI+ Q+ Q V +H Q +IH D+K N L+ KL DFG
Sbjct: 429 YTTNLPL----YSLMNILYQMLQAVNYIH--QHGVIHSDLKPANFLMVSGR-LKLIDFGI 481
Query: 181 VSGV------IRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
S + I FNY+ + + +T+ D + + I KSD+W+LG
Sbjct: 482 ASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPK-IKISTKSDVWSLGC 540
Query: 235 FLYKTCYYTTPF-------EKNGESAILASKFEFPAYPRYSD-RVKNLISVMLRVDPLKR 286
LY Y TPF K + E+PA P Y + ++ L+++P KR
Sbjct: 541 ILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPPYYPIMLVHMAKNCLQLNPKKR 600
Query: 287 PNICQVVE 294
P+ ++++
Sbjct: 601 PSCTELLQ 608
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 72.8 bits (177), Expect = 2e-12
Identities = 78/323 (24%), Positives = 132/323 (40%), Gaps = 46/323 (14%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSM 76
+G +L+ + G +A V V + D + V +K+ +V D ++ ++ E
Sbjct: 240 LGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKV--VKKELVNDDEDIDWVQTEKHVF 297
Query: 77 KALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILN 136
+ + F+V T+S ++ ++EY +GG L+ M Q +L E
Sbjct: 298 EQASNHPFLVGLHSCFQTES-------RLFFVIEYVNGGDLMFHMQR--QRKLPEEHARF 348
Query: 137 IMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNY 196
+++S + +H + +I+RD+K++NVLL KL D+G +R T F
Sbjct: 349 YSAEISLALNYLH--ERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTF-- 404
Query: 197 VQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES---- 252
T Y PE++ RG D WALGV +++ +PF+ G S
Sbjct: 405 -------CGTPNYIAPEIL---RGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPD 454
Query: 253 ---------AILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
IL + P S + +++ L DP +R C + IQG P
Sbjct: 455 QNTEDYLFQVILEKQIRIPR--SLSVKAASVLKSFLNKDPKERLG-CHPQTGFADIQGHP 511
Query: 304 CPIKNFYLLRMMDKQEQPRVSPP 326
F+ D EQ +V PP
Sbjct: 512 -----FFRNVDWDMMEQKQVVPP 529
>CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 740
Score = 72.8 bits (177), Expect = 2e-12
Identities = 71/292 (24%), Positives = 124/292 (42%), Gaps = 41/292 (14%)
Query: 22 VKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRG 81
++V ++ G F V+S + PD LK+V V +K E + + +R
Sbjct: 52 IQVGDHIGVGTFGAVFSGNWTLPDG--SQRTIALKKVFVLEK--------EAEILSKIRH 101
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFE-------I 134
I Y AT + + +++ EY G L DF+++ +
Sbjct: 102 KNIIQFYGICKATGN-------DFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVV 154
Query: 135 LNIMSQVSQGVAAMHA-LQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEE 193
+ SQ++ G+ +H +IHRD+K +NV+L KN K+CDFG+ +++
Sbjct: 155 VKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGT----------SKD 204
Query: 194 FNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE-- 251
+ TA + PEMI GL +D+W+ GV L++ P++ E
Sbjct: 205 LTHSCTAPSWGGTAAWMSPEMILQSEGL--TTATDVWSYGVVLWEILSKEVPYKDYSEFR 262
Query: 252 --SAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQG 301
+ I S P +K L+S ++ P R N+ Q+ E++R+ G
Sbjct: 263 IFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGELNRLAG 314
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 72.8 bits (177), Expect = 2e-12
Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 39/249 (15%)
Query: 56 KRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGG 115
KR +V +K + +R EV M L G IV ++ K + V+L+ME C+GG
Sbjct: 101 KRKLV-NKEDIEDVRREVQIMHHLTGQPNIVELKGAYEDK-------HSVHLVMELCAGG 152
Query: 116 GLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLL---SKNHE 172
L D + + E +++ + Q + H++ +IHRD+K EN LL +N
Sbjct: 153 ELFDRIIAK--GHYSERAAASLLRTIVQIIHTCHSMG--VIHRDLKPENFLLLSKDENSP 208
Query: 173 FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIW 230
K DFG Y ++ K+ +A Y PE++ G ++DIW
Sbjct: 209 LKATDFGL------------SVFYKPGEVFKDIVGSAYYIAPEVLRRKYG----PEADIW 252
Query: 231 ALGVFLYKTCYYTTPFEKNGE----SAILASKFEFPA--YPRYSDRVKNLISVMLRVDPL 284
++GV LY PF E +AIL+ + +F + +P S + K+L+ ML DP
Sbjct: 253 SIGVMLYILLCGVPPFWAESENGIFNAILSGQVDFSSDPWPVISPQAKDLVRKMLNSDPK 312
Query: 285 KRPNICQVV 293
+R QV+
Sbjct: 313 QRLTAAQVL 321
>At2g23030 [T] KOG0583 Serine/threonine protein kinase
Length = 339
Score = 72.8 bits (177), Expect = 2e-12
Identities = 63/214 (29%), Positives = 100/214 (46%), Gaps = 32/214 (14%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL 166
++MEY +GG L + +++ R E E Q+ GV +HALQ + HRD+K+EN L
Sbjct: 75 IVMEYAAGGELFERISS--VGRFSEAEARYFFQQLICGVHYLHALQ--ICHRDLKLENTL 130
Query: 167 L--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLP 222
L S K+CDFG S S V+ + P++T T Y PE+ +
Sbjct: 131 LDGSPAPRLKICDFGYSKSSVLHSNPKSTVG------------TPAYIAPEV---FCRSE 175
Query: 223 IDEKS-DIWALGVFLYKTCYYTTPFE--------KNGESAILASKFEFPAYPRYSDRVKN 273
D KS D+W+ GV LY PFE + I+A ++ P Y S+ +
Sbjct: 176 YDGKSVDVWSCGVALYVMLVGAYPFEDPKDPRNFRKTVQKIMAVNYKIPGYVHISEDCRK 235
Query: 274 LISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIK 307
L+S + +PL R + ++ ++ +P +K
Sbjct: 236 LLSRIFVANPLHRSTLKEIKSHAWFLKNLPRELK 269
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 72.4 bits (176), Expect = 2e-12
Identities = 50/168 (29%), Positives = 84/168 (49%), Gaps = 14/168 (8%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E++ +K ++ I +Y + KSP +++L+ME+C G + D + N
Sbjct: 66 IKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNT 124
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L+E I I ++ +G+A +H +IHRDIK +NVLL++N E KL DFG + + R
Sbjct: 125 LKEDWIAYISREILRGLAHLHIHH--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV 182
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
F Y + PE+I D D +SD+W+ G+
Sbjct: 183 GRRNTFIGTPY---------WMAPEVIACDENPDATYDYRSDLWSCGI 221
>Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1212
Score = 72.4 bits (176), Expect = 2e-12
Identities = 50/168 (29%), Positives = 84/168 (49%), Gaps = 14/168 (8%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E++ +K ++ I +Y + KSP +++L+ME+C G + D + N
Sbjct: 66 IKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNT 124
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L+E I I ++ +G+A +H +IHRDIK +NVLL++N E KL DFG + + R
Sbjct: 125 LKEDWIAYISREILRGLAHLHIHH--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV 182
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
F Y + PE+I D D +SD+W+ G+
Sbjct: 183 GRRNTFIGTPY---------WMAPEVIACDENPDATYDYRSDLWSCGI 221
>Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1320
Score = 72.4 bits (176), Expect = 2e-12
Identities = 50/168 (29%), Positives = 84/168 (49%), Gaps = 14/168 (8%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E++ +K ++ I +Y + KSP +++L+ME+C G + D + N
Sbjct: 66 IKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNT 124
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L+E I I ++ +G+A +H +IHRDIK +NVLL++N E KL DFG + + R
Sbjct: 125 LKEDWIAYISREILRGLAHLHIHH--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV 182
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
F Y + PE+I D D +SD+W+ G+
Sbjct: 183 GRRNTFIGTPY---------WMAPEVIACDENPDATYDYRSDLWSCGI 221
>Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1166
Score = 72.4 bits (176), Expect = 2e-12
Identities = 50/168 (29%), Positives = 84/168 (49%), Gaps = 14/168 (8%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E++ +K ++ I +Y + KSP +++L+ME+C G + D + N
Sbjct: 66 IKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDD-QLWLVMEFCGAGSITDLVKNTKGNT 124
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
L+E I I ++ +G+A +H +IHRDIK +NVLL++N E KL DFG + + R
Sbjct: 125 LKEDWIAYISREILRGLAHLHIHH--VIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTV 182
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
F Y + PE+I D D +SD+W+ G+
Sbjct: 183 GRRNTFIGTPY---------WMAPEVIACDENPDATYDYRSDLWSCGI 221
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 72.4 bits (176), Expect = 2e-12
Identities = 46/167 (27%), Positives = 83/167 (49%), Gaps = 10/167 (5%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYE-VYLLMEYCSGGGLIDFMNTRLQN 127
++ E++ +K ++ + +Y + K P + G ++ ++L+ME+C G + D +
Sbjct: 62 IKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGG 121
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
L+E I I ++ +G+ +H Q +IHRDIK +NVLL+ + E KL DFG + + +
Sbjct: 122 SLKEEWIAYICREILRGLYHLH--QSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKT 179
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
F Y + A PE D +SD+W+LG+
Sbjct: 180 VGRRNTFIGTPYWMAPEVIACDESPE-------ATYDSRSDLWSLGI 219
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 72.4 bits (176), Expect = 2e-12
Identities = 46/167 (27%), Positives = 83/167 (49%), Gaps = 10/167 (5%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYE-VYLLMEYCSGGGLIDFMNTRLQN 127
++ E++ +K ++ + +Y + K P + G ++ ++L+ME+C G + D +
Sbjct: 62 IKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGG 121
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
L+E I I ++ +G+ +H Q +IHRDIK +NVLL+ + E KL DFG + + +
Sbjct: 122 SLKEEWIAYICREILRGLYHLH--QSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKT 179
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
F Y + A PE D +SD+W+LG+
Sbjct: 180 VGRRNTFIGTPYWMAPEVIACDESPE-------ATYDSRSDLWSLGI 219
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 72.4 bits (176), Expect = 2e-12
Identities = 46/167 (27%), Positives = 83/167 (49%), Gaps = 10/167 (5%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYE-VYLLMEYCSGGGLIDFMNTRLQN 127
++ E++ +K ++ + +Y + K P + G ++ ++L+ME+C G + D +
Sbjct: 62 IKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGG 121
Query: 128 RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA 187
L+E I I ++ +G+ +H Q +IHRDIK +NVLL+ + E KL DFG + + +
Sbjct: 122 SLKEEWIAYICREILRGLYHLH--QSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKT 179
Query: 188 PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
F Y + A PE D +SD+W+LG+
Sbjct: 180 VGRRNTFIGTPYWMAPEVIACDESPE-------ATYDSRSDLWSLGI 219
>At1g10940 [T] KOG0583 Serine/threonine protein kinase
Length = 363
Score = 72.4 bits (176), Expect = 2e-12
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 34/211 (16%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL 166
+ MEY +GG L + + + R E E Q+ GV+ HA+Q + HRD+K+EN L
Sbjct: 75 IAMEYAAGGELFERICSA--GRFSEDEARYFFQQLISGVSYCHAMQ--ICHRDLKLENTL 130
Query: 167 L--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDL--YRG 220
L S K+CDFG S S ++ + P++T T Y PE++ Y G
Sbjct: 131 LDGSPAPRLKICDFGYSKSSLLHSRPKSTVG------------TPAYIAPEVLSRREYDG 178
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGE--------SAILASKFEFPAYPRYSDRVK 272
+ +D+W+ GV LY PFE + I+A +++ P Y S K
Sbjct: 179 ----KMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCK 234
Query: 273 NLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
NL+S + + LKR I ++ + ++ +P
Sbjct: 235 NLLSRIFVANSLKRITIAEIKKHSWFLKNLP 265
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 72.4 bits (176), Expect = 2e-12
Identities = 51/194 (26%), Positives = 93/194 (47%), Gaps = 17/194 (8%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+Y++M +C GG L + + L E +++ Q++ + +H + ++HRD+K +N
Sbjct: 79 LYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLH--EKHILHRDLKTQN 136
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID 224
V L++ + K+ D G ++ V+ N+ T Y PE L+ P +
Sbjct: 137 VFLTRTNIIKVGDLG-IARVLE--------NHCDMASTLIGTPYYMSPE---LFSNKPYN 184
Query: 225 EKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFE--FPAYPR-YSDRVKNLISVMLRV 281
KSD+WALG +Y+ F ++++ E PA PR YS + LI ML
Sbjct: 185 YKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPAMPRDYSPELAELIRTMLSK 244
Query: 282 DPLKRPNICQVVEE 295
P +RP++ ++ +
Sbjct: 245 RPEERPSVRSILRQ 258
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 72.0 bits (175), Expect = 3e-12
Identities = 57/195 (29%), Positives = 93/195 (47%), Gaps = 23/195 (11%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
YL+ME C GG L+ + + RL+E E + Q+ V +H + ++HRD+KIEN+
Sbjct: 137 YLVMELCPGGNLMHKIYEK--KRLEESEARRYIRQLISAVEHLH--RAGVVHRDLKIENL 192
Query: 166 LLSKNHEFKLCDFG--SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
LL +++ KL DFG + +G++ Y + + Y PE++ + P
Sbjct: 193 LLDEDNNIKLIDFGLSNCAGIL---------GYSDPFSTQCGSPAYAAPELLARKKYGP- 242
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGES-----AILASKFEFPAYPRYSDRVKNLISVM 278
K D+W++GV +Y T PF S + K P + S + + +
Sbjct: 243 --KIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSL 300
Query: 279 LRVDPLKRPNICQVV 293
L DP+KRPNI Q +
Sbjct: 301 LEPDPVKRPNIQQAL 315
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 72.0 bits (175), Expect = 3e-12
Identities = 92/400 (23%), Positives = 168/400 (42%), Gaps = 49/400 (12%)
Query: 24 VLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNK 83
+L+ L G + V+ D V D VA LK V + ++TL+ E+ +K R +
Sbjct: 19 LLQRLGGGTYGEVFKAR----DKVSGDLVA-LKMVKMEPDDDVSTLQKEILILKTCR-HA 72
Query: 84 FIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQ 143
IV+Y S+ + + ++++ ME+C G L D ++ L E +I + +V Q
Sbjct: 73 NIVAYHGSY-------LWLQKLWICMEFCGAGSLQDIY--QVTGSLSELQISYVCREVLQ 123
Query: 144 GVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMK 203
G+A +H+ + IHRDIK N+L++ E +L DFG +S I A +++
Sbjct: 124 GLAYLHSQKK--IHRDIKGANILINDAGEVRLADFG-ISAQIGATL-ARRLSFI------ 173
Query: 204 NTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAILASKFEFP 262
T + PE+ + +E DIW+LG+ + P F+ + +
Sbjct: 174 -GTPYWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGY 232
Query: 263 AYPRYSDRVK------NLISVMLRVDPLKRPNICQVVEEVSRIQGIPCP-IKNFYLLRMM 315
PR ++ K N I V L P KRP+ +++ Q + P + +L ++
Sbjct: 233 QPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSH----QLVSQPGLNRGLILDLL 288
Query: 316 DKQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQVVSNVQTPSKTASIQHLPYLHVSKS 375
DK + P P LPP + +++ +++S+ +P +
Sbjct: 289 DKLKNPGKGP----------SIGDIEDEEPELPPAIPRRIRSTHRSSSL-GIPDADCCRR 337
Query: 376 QPMVTQQDLLSQKQPAGKTVPQTVSNYTSSDPFSKIDRSA 415
+ + + PA Q + SS P ++ S+
Sbjct: 338 HMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESS 377
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 72.0 bits (175), Expect = 3e-12
Identities = 60/224 (26%), Positives = 100/224 (43%), Gaps = 30/224 (13%)
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
EVD ++ + G+ I+ D++ T + +L+ + G L D++ ++ L E
Sbjct: 74 EVDILRKVSGHPNIIQLKDTYETNT-------FFFLVFDLMKRGELFDYLTEKVT--LSE 124
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNT 191
E IM + + + +H L ++HRD+K EN+LL N KL DFG + R
Sbjct: 125 KETRKIMRALLEVICTLHKLN--IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLR 182
Query: 192 EEFNYVQYDIMKNTTAQYRCPEMIDLYRGLP---IDEKSDIWALGVFLYKTCYYTTPFEK 248
E T Y PE+I+ ++ D+W+ GV +Y + PF
Sbjct: 183 EVCG----------TPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWH 232
Query: 249 NGE----SAILASKFEF--PAYPRYSDRVKNLISVMLRVDPLKR 286
+ I++ ++F P + YSD VK+L+S L V P R
Sbjct: 233 RKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNR 276
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 72.0 bits (175), Expect = 3e-12
Identities = 74/248 (29%), Positives = 110/248 (43%), Gaps = 31/248 (12%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
D+ + L E+ SM+ L I Y V + +++L+MEY GG L +
Sbjct: 111 DQKTQRLLSREISSMEKLHHPNIIRLY--------EVVETLSKLHLVMEYAGGGELFGKI 162
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
+T + +L E E I SQ+ V MH Q +IHRD+K ENV + N K+ DFG
Sbjct: 163 ST--EGKLSEPESKLIFSQIVSAVKHMHENQ--IIHRDLKAENVFYTSNTCVKVGDFG-F 217
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGVFLYKT 239
S V + F + Y PE+ + Y G+ + DIWALGV LY
Sbjct: 218 STVSKKGEMLNTF---------CGSPPYAAPELFRDEHYIGIYV----DIWALGVLLYFM 264
Query: 240 CYYTTPFEKNGESAILASKFE--FPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVS 297
T PF + + S E + P S+ LI +L+ P +R I ++ +
Sbjct: 265 VTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMND-E 323
Query: 298 RIQGIPCP 305
+QG+P P
Sbjct: 324 WMQGVPYP 331
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 72.0 bits (175), Expect = 3e-12
Identities = 66/272 (24%), Positives = 124/272 (45%), Gaps = 45/272 (16%)
Query: 67 NTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN---- 122
N++++EV+ +K ++ + I+ YIDS + + + +M+Y GG L +N
Sbjct: 48 NSIQSEVNLLKKVQ-HPLIIGYIDSFIMDNQLGI-------VMQYAEGGTLERLINDQRA 99
Query: 123 ---TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE-FKLCDF 178
+ ++ E +L+ +Q+ +A H Q ++HRD+K +N+L+++ KL DF
Sbjct: 100 IKDSNMREYFPEKTVLDYFTQIL--IALNHMHQKNIVHRDLKPQNILMNRRKTVLKLSDF 157
Query: 179 GSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYK 238
G ++E T Y PE+ + P ++KSD+W+LG LY+
Sbjct: 158 GI----------SKELGTKSAASTVIGTPNYLSPEICE---SRPYNQKSDMWSLGCVLYE 204
Query: 239 TCYYTTPFEKNGESAI---LASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
F+ AI + + P S+ VK L+ +L+ KRP++ Q++ +
Sbjct: 205 LLQLERAFDGENLPAIVMKITRSKQNPLGDHVSNDVKMLVENLLKTHTDKRPDVSQLLSD 264
Query: 296 VSRIQGIPCPIKNFYLLRMMDKQEQPRVSPPP 327
P+ YL+ + + R+ PPP
Sbjct: 265 ---------PLVLPYLISI--HCDLGRIEPPP 285
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 72.0 bits (175), Expect = 3e-12
Identities = 79/292 (27%), Positives = 131/292 (44%), Gaps = 42/292 (14%)
Query: 26 KYLASGGFAHVY-SVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKF 84
+ L G F VY EI+ + V + + + V + + ++ E+ M+ +R +
Sbjct: 19 RLLGKGTFGKVYYGKEITTGESVA---IKIINKDQVKREGMMEQIKREISIMRLVR-HPN 74
Query: 85 IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQG 144
IV + ATK+ +++ +MEY GG L + ++ +L+E Q+
Sbjct: 75 IVELKEVMATKT-------KIFFIMEYVKGGELFSKI---VKGKLKEDSARKYFQQLISA 124
Query: 145 VAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKN 204
V H+ + HRD+K EN+L+ +N + K+ DF G+ P + D + +
Sbjct: 125 VDFCHSRG--VSHRDLKPENLLVDENGDLKVSDF----GLSALPEQ------ILQDGLLH 172
Query: 205 T---TAQYRCPEMIDL--YRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNG----ESAIL 255
T T Y PE++ Y G K DIW+ G+ LY PF+ I
Sbjct: 173 TQCGTPAYVAPEVLRKKGYDG----AKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIF 228
Query: 256 ASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIK 307
S+FE+P P +S K LIS +L VDP KR +I ++ + I PI+
Sbjct: 229 KSEFEYP--PWFSPESKRLISKLLVVDPNKRISIPAIMRTPWFRKNINSPIE 278
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 72.0 bits (175), Expect = 3e-12
Identities = 79/300 (26%), Positives = 126/300 (41%), Gaps = 55/300 (18%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGG----FAHVYSVEISPPDPVCPDNVACLKRVV 59
P++ Y ++ GS + +L S G F + E+SPP N
Sbjct: 100 PELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMN-------- 151
Query: 60 VPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLID 119
EVD L + IVSY+ S + + + M EY GG L
Sbjct: 152 ------------EVDVFSKLH-HPNIVSYLGSFIKDNTLLIEM-------EYADGGTLAQ 191
Query: 120 FMNTRLQNRLQ--EFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCD 177
+ R Q +L E I+ + Q+S + MH+ ++HRD+K NV L++ K+ D
Sbjct: 192 IIAER-QGKLHFPERYIIAVFEQISSAINYMHSEN--ILHRDLKTANVFLNRRGIVKIGD 248
Query: 178 FGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLY 237
FG +S ++ + + Y Y PEM + G D KSDIWALG L
Sbjct: 249 FG-ISKIMNTKIHAQTVLGTPY---------YFSPEMCE---GKEYDNKSDIWALGCILG 295
Query: 238 KTCYYTTPFEKNGES----AILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+ C F + S I+A + P Y+ +++L+S +L+V+ +RP +V+
Sbjct: 296 EMCCLKKTFAASNLSELVTKIMAGNYT-PVPSGYTSGLRSLMSNLLQVEAPRRPTASEVL 354
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 71.6 bits (174), Expect = 4e-12
Identities = 59/192 (30%), Positives = 92/192 (47%), Gaps = 28/192 (14%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
++YL++EY G L + + R L E E + Q+ GV+ HAL ++HRD+K E
Sbjct: 105 DLYLVLEYAEKGELFNLLVER--GPLPEHEAIRFFRQIIIGVSYCHALG--IVHRDLKPE 160
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGL 221
N+LL + K+ DFG A TE +++ + + Y PE++ G+
Sbjct: 161 NLLLDHKYNIKIADFG------MAALETEG------KLLETSCGSPHYAAPEIVS---GI 205
Query: 222 PIDE-KSDIWALGVFLYKTCYYTTPF-EKNGESAILASK-----FEFPAYPRYSDRVKNL 274
P SD+W+ GV L+ PF E++G L K FE P+ S ++L
Sbjct: 206 PYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDL 265
Query: 275 ISVMLRVDPLKR 286
I +L VDP +R
Sbjct: 266 IRKILTVDPERR 277
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 71.6 bits (174), Expect = 4e-12
Identities = 59/197 (29%), Positives = 97/197 (48%), Gaps = 29/197 (14%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
Y+L EY GG L++++ R +L E + Q+ + +H + ++HRD+KIENV
Sbjct: 126 YILFEYVPGGQLLEYILAR--GKLDEDLARSFAMQLINALVYLH--KNFIVHRDLKIENV 181
Query: 166 LLSK-NHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGL 221
LL++ + + KL DFG N+ D + T + + PE++D
Sbjct: 182 LLTQDSRQVKLIDFGL-------------SNFYSKDDLLRTYCGSLYFAAPELLDAKP-- 226
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFEKNG----ESAILASKFEFPAYPRYSDRVKNLISV 277
I + D+W+LGV +Y PF+ S I + K EFP+Y S+ +LI+
Sbjct: 227 YIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSY--ISEDCCSLIAA 284
Query: 278 MLRVDPLKRPNICQVVE 294
ML V+P KR ++ Q +
Sbjct: 285 MLNVNPRKRCSLEQAAK 301
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 71.6 bits (174), Expect = 4e-12
Identities = 60/231 (25%), Positives = 106/231 (44%), Gaps = 36/231 (15%)
Query: 20 HQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVP-DKASLNTLRAEVD---S 75
HQ + L+ + G F V+ + V + LK V + K + TL E++
Sbjct: 4 HQYRDLQLIGQGSFGSVFRAQ-----DVESSKIVALKVVDLDATKDQIETLTQEINFLID 58
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEIL 135
+ ++ K+ S++D + +++ MEYC GG +D + +L E I
Sbjct: 59 LNSVHITKYYASFVDG-----------FRLWITMEYCDGGSCLDLL--KLSGTFSERVIA 105
Query: 136 NIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFN 195
+M QV + + +H +HRDIK N+L K+ KL DFG VSG + + R+ + +
Sbjct: 106 EVMRQVLEALVYLHGQGK--MHRDIKAANILTMKDGLVKLADFG-VSGQLESLRDKND-D 161
Query: 196 YVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF 246
+V T + PE++ + + K+DIW+LG+ Y+ P+
Sbjct: 162 FV-------GTPFWMAPEVV---KQTGYNYKADIWSLGITAYELATGEPPY 202
>CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 425
Score = 71.6 bits (174), Expect = 4e-12
Identities = 77/285 (27%), Positives = 134/285 (47%), Gaps = 48/285 (16%)
Query: 62 DKASLNTLRAEVDSMKALR---------GNKFIVSYIDSHATKSPVNVGMYEVYLLMEYC 112
DK +L LR D+ KA R G+ +VS D + K+ N G+ + ++ME
Sbjct: 96 DKFALKVLR---DTQKARREVELHVMASGHGHVVSVHDVY--KNSYN-GVDCLLVVMENM 149
Query: 113 SGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL---LSK 169
GG L + + R Q E E I++++ VA +H + + HRD+K EN+L +
Sbjct: 150 KGGELFNRIQERGQKAFTEREAAGIVNEICSAVAHLHRMS--IAHRDLKPENLLYVTTAS 207
Query: 170 NHEFKLCDFGSVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSD 228
N KL DFG + P+ + + Y Y PE++ + D+ D
Sbjct: 208 NAALKLTDFGFAKKTDESEPQGLKTACFTPY---------YCAPEVLGTEK---YDKSCD 255
Query: 229 IWALGVFLY-KTCYYTTPFEKNGE-------SAILASKFEFPA--YPRYSDRVKNLISVM 278
+W++GV +Y C Y + ++G+ + I + ++ FP+ + S+ K+LI +
Sbjct: 256 LWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQYTFPSPEWDCVSEAAKDLIRKL 315
Query: 279 LRVDPLKRPNICQVVEE--VSRIQGIP-CPIKNFYLLRMMDKQEQ 320
LR +P +R I Q +E +S + +P P+ F + D++EQ
Sbjct: 316 LRTEPTERITIEQTMEHKWISHYRRVPDTPL--FTSSNLNDQREQ 358
>CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 443
Score = 71.6 bits (174), Expect = 4e-12
Identities = 77/285 (27%), Positives = 134/285 (47%), Gaps = 48/285 (16%)
Query: 62 DKASLNTLRAEVDSMKALR---------GNKFIVSYIDSHATKSPVNVGMYEVYLLMEYC 112
DK +L LR D+ KA R G+ +VS D + K+ N G+ + ++ME
Sbjct: 114 DKFALKVLR---DTQKARREVELHVMASGHGHVVSVHDVY--KNSYN-GVDCLLVVMENM 167
Query: 113 SGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL---LSK 169
GG L + + R Q E E I++++ VA +H + + HRD+K EN+L +
Sbjct: 168 KGGELFNRIQERGQKAFTEREAAGIVNEICSAVAHLHRMS--IAHRDLKPENLLYVTTAS 225
Query: 170 NHEFKLCDFGSVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSD 228
N KL DFG + P+ + + Y Y PE++ + D+ D
Sbjct: 226 NAALKLTDFGFAKKTDESEPQGLKTACFTPY---------YCAPEVLGTEK---YDKSCD 273
Query: 229 IWALGVFLY-KTCYYTTPFEKNGE-------SAILASKFEFPA--YPRYSDRVKNLISVM 278
+W++GV +Y C Y + ++G+ + I + ++ FP+ + S+ K+LI +
Sbjct: 274 LWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQYTFPSPEWDCVSEAAKDLIRKL 333
Query: 279 LRVDPLKRPNICQVVEE--VSRIQGIP-CPIKNFYLLRMMDKQEQ 320
LR +P +R I Q +E +S + +P P+ F + D++EQ
Sbjct: 334 LRTEPTERITIEQTMEHKWISHYRRVPDTPL--FTSSNLNDQREQ 376
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 71.6 bits (174), Expect = 4e-12
Identities = 70/242 (28%), Positives = 109/242 (44%), Gaps = 38/242 (15%)
Query: 72 EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQE 131
E ++ ++G+ IV D H+ P++ YL+ME +G L++ R R E
Sbjct: 424 EARILEMVQGHPNIVQLHDVHS--DPLHF-----YLVMEILTGNELLE--RIRKLERFTE 474
Query: 132 FEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL---LSKNHEFKLCDFGSVS------ 182
E +IM Q+ V +H + ++HRD+K EN+L + + +L DFG
Sbjct: 475 SEAADIMRQLVSAVKYLHDKR--IVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSM 532
Query: 183 -------GVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLP-IDEKSDIWALGV 234
V+R N+ + T QY PE++D+ P +E+ D+W+LGV
Sbjct: 533 EQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGV 592
Query: 235 FLYKTCYYTTPFEKNG--ESA------ILASKFEFP--AYPRYSDRVKNLISVMLRVDPL 284
L+ PF ESA I ++F F A+ S KNLI+ +L VDP
Sbjct: 593 VLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVDPK 652
Query: 285 KR 286
KR
Sbjct: 653 KR 654
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/256 (23%), Positives = 113/256 (43%), Gaps = 30/256 (11%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSV-EISPPDPVCPDNVACLKRV-VVPDKASLNTLRAEVD 74
V +L+ L G + V+ V ++ D + L++ V+ + +L AE
Sbjct: 12 VSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQ 71
Query: 75 SMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEI 134
++ LRG F+V+ + T + +++++MEY GG L + +R L+
Sbjct: 72 VLERLRGTPFLVNLFYAFQTDT-------KLHIVMEYVRGGELFTHLCSRGHFDLEAARF 124
Query: 135 LNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEF 194
+++++ + ++H Q +I+RD+K+EN+LL + KL DFG + P +
Sbjct: 125 --VIAELVVAIDSLH--QRKVIYRDLKLENILLDEEGHVKLTDFG--LSKLFLPGELDRA 178
Query: 195 NYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNG---- 250
N T +Y PE+I+ G + D W+LGV ++ +PF +G
Sbjct: 179 N------SYCGTIEYMSPEVINRPEG-GYSDVVDWWSLGVISFELLTGCSPFTVDGAQNS 231
Query: 251 ----ESAILASKFEFP 262
I+ K FP
Sbjct: 232 SKDIAKRIMTKKVPFP 247
>At5g20930 [T] KOG1151 Tousled-like protein kinase
Length = 799
Score = 71.6 bits (174), Expect = 4e-12
Identities = 76/298 (25%), Positives = 125/298 (41%), Gaps = 38/298 (12%)
Query: 16 PVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDS 75
PV + + +L L GGF+ VY D V VAC L+ L A+
Sbjct: 403 PVLNSRYALLNLLGKGGFSEVYKAY----DLVDHRYVAC----------KLHGLNAQWSE 448
Query: 76 MK-------ALRGNKFIVSYIDSHATK--SPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQ 126
K A R + S + H + ++ M+ ++EYCSG L + +
Sbjct: 449 EKKQSYIRHANRECEIHKSLVHHHIVRLWDKFHIDMHTFCTVLEYCSGKDLDAVL--KAT 506
Query: 127 NRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIR 186
+ L E E I+ Q+ QG+ ++ +IH D+K NVL + K+ DFG +S ++
Sbjct: 507 SNLPEKEARIIIVQIVQGLVYLNKKSQKIIHYDLKPGNVLFDEFGVAKVTDFG-LSKIVE 565
Query: 187 APRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF 246
++ T Y PE +L + I K D+W++GV Y+ + PF
Sbjct: 566 DNVGSQGMELTSQGA---GTYWYLPPECFELNKTPMISSKVDVWSVGVLFYQMLFGKRPF 622
Query: 247 EKN--------GESAILASKFEFP-AYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ ++ I A K EFP P S+ K+LI L + RP++ + ++
Sbjct: 623 GHDQSQERILREDTIIKAKKVEFPVTRPAISNEAKDLIRRCLTYNQEDRPDVLTMAQD 680
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 71.6 bits (174), Expect = 4e-12
Identities = 70/241 (29%), Positives = 107/241 (44%), Gaps = 34/241 (14%)
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
KA + +R E+ M+ L G IV + ++ + VN L+ME C+GG L D +
Sbjct: 130 KADKDDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVN-------LVMELCAGGELFDRII 182
Query: 123 TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFG 179
+ E ++ Q+ V H + ++HRD+K EN LLS E K DFG
Sbjct: 183 AK--GHYTERAAASVCRQIVNVVKICHFMG--VLHRDLKPENFLLSSKDEKALIKATDFG 238
Query: 180 SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
+ E V DI+ +A Y PE++ G ++ DIW+ G+ LY
Sbjct: 239 LSVFI--------EEGKVYRDIV--GSAYYVAPEVLRRRYG----KEVDIWSAGIILYIL 284
Query: 240 CYYTTPF----EKNGESAILASKFEFPA--YPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
PF EK AIL +F + +P S K+L+ ML DP +R + V+
Sbjct: 285 LSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDLVRRMLTADPKRRISAADVL 344
Query: 294 E 294
+
Sbjct: 345 Q 345
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 71.6 bits (174), Expect = 4e-12
Identities = 72/241 (29%), Positives = 109/241 (44%), Gaps = 34/241 (14%)
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
K +R E+ M+ L G IV + ++ + VN L+ME C+GG L D +
Sbjct: 112 KGDKEDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVN-------LVMELCAGGELFDRIL 164
Query: 123 TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFG 179
+ E ++ Q+ V H + ++HRD+K EN LLS E K DFG
Sbjct: 165 AK--GHYSERAAASVCRQIVNVVNICHFMG--VMHRDLKPENFLLSSKDEKALIKATDFG 220
Query: 180 SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
+S I R V DI+ +A Y PE++ G I DIW+ G+ LY
Sbjct: 221 -LSVFIEEGR-------VYKDIV--GSAYYVAPEVLKRRYGKEI----DIWSAGIILYIL 266
Query: 240 CYYTTPF----EKNGESAILASKFEFPA--YPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
PF EK AIL + +F + +P S+ K+L+ ML DP +R + +V+
Sbjct: 267 LSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVL 326
Query: 294 E 294
+
Sbjct: 327 K 327
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 71.6 bits (174), Expect = 4e-12
Identities = 74/267 (27%), Positives = 124/267 (45%), Gaps = 41/267 (15%)
Query: 50 DNVACLKRVVVPDKASLNTLRA----EVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEV 105
DNVA +V+ +K N + A E+ +MK ++ + ++ + A+K+ ++
Sbjct: 55 DNVAI--KVIDKEKVLKNKMIAQIKREISTMKLIK-HPNVIRMFEVMASKT-------KI 104
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
Y ++E+ +GG L D +++ RL+E E Q+ V H+ + HRD+K EN+
Sbjct: 105 YFVLEFVTGGELFDKISSN--GRLKEDEARKYFQQLINAVDYCHSRG--VYHRDLKPENL 160
Query: 166 LLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTA---QYRCPEMIDL--YRG 220
LL N K+ DF G+ P+ Q D + +TT Y PE+I+ Y G
Sbjct: 161 LLDANGALKVSDF----GLSALPQ--------QEDGLLHTTCGTPNYVAPEVINNKGYDG 208
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS--KFEFPAYPRYSDRVKNLISVM 278
K+D+W+ GV L+ PFE + +++ K EF P +S K LI +
Sbjct: 209 ----AKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASAKKLIKRI 264
Query: 279 LRVDPLKRPNICQVVEEVSRIQGIPCP 305
L +P R +V+E +G P
Sbjct: 265 LDPNPATRITFAEVIENEWFKKGYKAP 291
>7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 678
Score = 71.6 bits (174), Expect = 4e-12
Identities = 53/194 (27%), Positives = 96/194 (49%), Gaps = 21/194 (10%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQP-PLIHRDIKIEN 164
YL+ME+ GG L +F++ +++ ++ Q ++G+A +HA+ P PLIHRD+K N
Sbjct: 86 YLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLN 145
Query: 165 VLL-SKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
+LL +K K+CDFG+V A ++T N +A + PE ++ G
Sbjct: 146 LLLTNKGRNLKICDFGTV-----ADKSTMMTN-------NRGSAAWMAPE---VFEGSKY 190
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKF----EFPAYPRYSDRVKNLISVML 279
EK DI++ + L++ PF+ + + K P R+++L++
Sbjct: 191 TEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACW 250
Query: 280 RVDPLKRPNICQVV 293
+ P RP++ +V
Sbjct: 251 KTVPEDRPSMQYIV 264
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 71.2 bits (173), Expect = 6e-12
Identities = 63/222 (28%), Positives = 94/222 (41%), Gaps = 25/222 (11%)
Query: 78 ALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNI 137
A + FIV+ S TK +YL MEYC GG + TR + E +
Sbjct: 377 ATSDHPFIVTLYHSFQTKD-------YLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFY 429
Query: 138 MSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG-SVSGVIRAPRNTEEFNY 196
S+V + +H L I+RD+K EN+LL ++ L DF S+ ++ Y
Sbjct: 430 ASEVVAALEYLHLL--GFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTY 487
Query: 197 VQYDIMKN--------TTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEK 248
+ I + T +Y PE+I RG D W LG+ +Y+ + TPF+
Sbjct: 488 LDTKICSDGFRTNSFVGTEEYLAPEVI---RGNGHTAAVDWWTLGILIYEMLFGCTPFKG 544
Query: 249 NGE----SAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
+ S IL +FP S K+LI +L + KR
Sbjct: 545 DNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKR 586
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 71.2 bits (173), Expect = 6e-12
Identities = 67/230 (29%), Positives = 105/230 (45%), Gaps = 33/230 (14%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
+R E++ LR + Y H K +YL++E+ G L + + R R
Sbjct: 163 VRREIEIQSNLRHKNILRLYGHFHDEK--------RIYLILEFAGRGEL--YQHLRRAKR 212
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
E + Q++ ++ +H + +IHRDIK EN+LL + E KL DFG + AP
Sbjct: 213 FSEEVASKYIFQMANALSYLH--KKHVIHRDIKPENILLGIDGEIKLSDFG---WSVHAP 267
Query: 189 RNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFE- 247
N T Y PEM++ G EK D+W+LGV Y+ PFE
Sbjct: 268 SNRR--------TTLCGTLDYLPPEMVE---GKEHTEKVDLWSLGVLTYEFLVGAPPFED 316
Query: 248 KNGESA----ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+G SA I + P++ ++LIS +L+ +P KR ++ QV+
Sbjct: 317 MSGHSATYKRIAKVDLKIPSF--VPPDARDLISRLLQHNPEKRMSLEQVM 364
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 71.2 bits (173), Expect = 6e-12
Identities = 53/193 (27%), Positives = 96/193 (49%), Gaps = 24/193 (12%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
E++++MEY GG L+DF+ + E + ++ Q+ + + +H + + HRDIK E
Sbjct: 243 ELFIVMEYVEGGDLMDFLIAN--GSIDEQDCKPLLKQLLETLLHLH--KQGVTHRDIKPE 298
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEF----NYVQYDIMKNTTAQYRCPEMIDLYR 219
N+L++ + K+ DFG + E F Y+ +++K+ + ++L
Sbjct: 299 NILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKS--------KNVNLDG 350
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAI--LASKFEFPAYPRYSDRVK----N 273
G D+K DIW+LG LY + PF + ++ L SK +P P + + +
Sbjct: 351 G--YDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGID 408
Query: 274 LISVMLRVDPLKR 286
LI+ ML ++P KR
Sbjct: 409 LINRMLEINPEKR 421
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 71.2 bits (173), Expect = 6e-12
Identities = 63/250 (25%), Positives = 114/250 (45%), Gaps = 35/250 (14%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
+ +E+ K G+K I+ + ++ ++P ++++E+ GG L D + +
Sbjct: 58 MASEIQLHKLCNGHKNIIHFYNT--AENP-----QWRWVVLEFAQGGDLFDKIEPDVG-- 108
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAP 188
+ E +Q+ +G++ MH+ + HRD+K EN+LL N K+ DFG S
Sbjct: 109 IDEDVAQFYFAQLMEGISFMHS--KGVAHRDLKPENILLDYNGNLKISDFGFAS------ 160
Query: 189 RNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
F+Y + N+ + Y PE+ Y G K D+W+ G+ L+ TP
Sbjct: 161 ----LFSYKGKSRLLNSPVGSPPYAAPEITQQYDG----SKVDVWSCGIILFALLLGNTP 212
Query: 246 FEK----NGESAILASKFEFPAYPRY---SDRVKNLISVMLRVDPLKRPNICQVVEEVSR 298
+++ G+ + + E P+Y + S ++I+ MLR DP KR ++ VV+
Sbjct: 213 WDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRYSVKHVVQHPWL 272
Query: 299 IQGIPCPIKN 308
P KN
Sbjct: 273 TSSTPFRTKN 282
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 70.9 bits (172), Expect = 7e-12
Identities = 74/311 (23%), Positives = 144/311 (45%), Gaps = 37/311 (11%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
++L+ + +G + VY D V + +A +K V + +++L+ E+ ++ R +
Sbjct: 17 ELLQRVGAGTYGDVYKAR----DTVTSE-LAAVKIVKLDPGDDISSLQQEITILRECR-H 70
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
+V+YI S+ +++ ME+C GG L + + L+E +I + +
Sbjct: 71 PNVVAYIGSYLRND-------RLWICMEFCGGGSLQEIYHAT--GPLEERQIAYVCREAL 121
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
+G+ +H+ IHRDIK N+LL+ + KL DFG VSG + A + +++
Sbjct: 122 KGLHHLHSQGK--IHRDIKGANLLLTLQGDVKLADFG-VSGELTA-SVAKRRSFI----- 172
Query: 203 KNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAIL---ASK 258
T + PE+ + R +E D+WALG+ + P F + A++ S
Sbjct: 173 --GTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSS 230
Query: 259 FEFPAY---PRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMM 315
F+ P R++ + + + L +P KRP ++++ Q +P + L +++
Sbjct: 231 FQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRAL----LTQLL 286
Query: 316 DKQEQPRVSPP 326
DK P + P
Sbjct: 287 DKASDPHLGTP 297
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 70.9 bits (172), Expect = 7e-12
Identities = 67/238 (28%), Positives = 104/238 (43%), Gaps = 33/238 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
++ +R EV ++AL G+K +V + D+ VY++ME C GG L+D + R
Sbjct: 168 AIEDVRREVKILRALTGHKNLVQFYDAFEDDE-------NVYIVMELCQGGELLDKILQR 220
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSV 181
+ E + +M Q+ VA H ++HRD+K EN L + E K DFG
Sbjct: 221 -GGKYSEVDAKKVMIQILSVVAYCHL--QGVVHRDLKPENFLFTTKDESSPLKAIDFGLS 277
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
V R E N DI+ +A Y PE++ G ++D+W++GV Y
Sbjct: 278 DYV----RPDERLN----DIV--GSAYYVAPEVLHRTYG----TEADMWSIGVIAYILLC 323
Query: 242 YTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+ PF ES I + FE +P S + + +L D KR Q +
Sbjct: 324 GSRPFWARSESGIFRAVLKAEPNFEEAPWPSLSPDAVDFVKRLLNKDYRKRLTAAQAL 381
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 70.9 bits (172), Expect = 7e-12
Identities = 68/273 (24%), Positives = 119/273 (42%), Gaps = 32/273 (11%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSM 76
VG +VLK + G F VY V + V ++V +K ++AE D +
Sbjct: 135 VGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIV--EKNHAEYMKAERDIL 192
Query: 77 KALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILN 136
+ + FIV S TK Y +YL++++ +GG L F Q +E
Sbjct: 193 TKI-DHPFIVQLKYSFQTK-------YRLYLVLDFINGGHL--FFQLYHQGLFREDLARV 242
Query: 137 IMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNY 196
+++ V+ +H + ++HRD+K EN+L+ + L DFG +EF
Sbjct: 243 YTAEIVSAVSHLH--EKGIMHRDLKPENILMDVDGHVMLTDFGL----------AKEFEE 290
Query: 197 VQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF---EKNGESA 253
T +Y PE++ RG D+ +D W++G+ LY+ PF + +
Sbjct: 291 NTRSNSMCGTTEYMAPEIV---RGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQK 347
Query: 254 ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
I+ K + P + S+ L+ +L+ +P +R
Sbjct: 348 IVKDKIKLPQF--LSNEAHALLKGLLQKEPERR 378
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 70.9 bits (172), Expect = 7e-12
Identities = 62/211 (29%), Positives = 98/211 (46%), Gaps = 30/211 (14%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+ + MEY +GG L + + + R E E Q+ GV+ HA+Q + HRD+K+EN
Sbjct: 73 IAIAMEYAAGGELFERICSA--GRFSEDEARYFFQQLISGVSYCHAMQ--ICHRDLKLEN 128
Query: 165 VLL--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRG 220
LL S K+CDFG S S ++ + P++T T Y PE++ RG
Sbjct: 129 TLLDGSPAPRLKICDFGYSKSSLLHSMPKSTVG------------TPAYIAPEVLS--RG 174
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFE--------KNGESAILASKFEFPAYPRYSDRVK 272
+ +D+W+ GV LY PFE K I+A K++ P Y S K
Sbjct: 175 EYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFKKTIQRIMAVKYKIPDYVHISQDCK 234
Query: 273 NLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
+L+S + + KR I + + ++ +P
Sbjct: 235 HLLSRIFVTNSNKRITIGDIKKHPWFLKNLP 265
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 70.5 bits (171), Expect = 9e-12
Identities = 66/248 (26%), Positives = 100/248 (39%), Gaps = 48/248 (19%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
K+L+ + G F +Y V+ + + +K + D + LR
Sbjct: 5 KILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYI------ADEVNILRNL 58
Query: 83 KF--IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQN--RLQEFEILNIM 138
K IV Y +S + +Y MEYC G L + + + R E E+L
Sbjct: 59 KHPNIVQYCGEELNRSAQVINLY-----MEYCGHGDLANLIQRYKEEKKRFTEQEVLKFF 113
Query: 139 SQV-----------------SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
+Q+ SQ + + ++HRDIK N+ L +N+ KL DFG
Sbjct: 114 TQLLLALYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFG-- 171
Query: 182 SGVIRAPRNTEEF--NYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
+ + NT F +YV T Y PE+I R P KSD+WALG +++
Sbjct: 172 --LSKLLDNTRVFTQSYVG-------TPYYMSPEII---RSSPYSAKSDVWALGCVIFEI 219
Query: 240 CYYTTPFE 247
C T PFE
Sbjct: 220 CMLTHPFE 227
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 70.5 bits (171), Expect = 9e-12
Identities = 63/227 (27%), Positives = 108/227 (46%), Gaps = 32/227 (14%)
Query: 70 RAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRL 129
R E ++ + G+ I++ IDS+ + S ++L+ + G L D++ ++ L
Sbjct: 75 RRETHILRQVAGHPHIITLIDSYESSS-------FMFLVFDLMRKGELFDYLTEKVA--L 125
Query: 130 QEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPR 189
E E +IM + + V+ +HA ++HRD+K EN+LL N + +L DFG S +
Sbjct: 126 SEKETRSIMRSLLEAVSFLHANN--IVHRDLKPENILLDDNMQIRLSDFG-FSCHLEPGE 182
Query: 190 NTEEF----NYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
E Y+ +I+K C M + + G ++ D+WA GV L+ + P
Sbjct: 183 KLRELCGTPGYLAPEILK-------C-SMDETHPG--YGKEVDLWACGVILFTLLAGSPP 232
Query: 246 FEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
F + +L +F P + S VK+LIS +L+VDP R
Sbjct: 233 FWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEAR 279
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 70.5 bits (171), Expect = 9e-12
Identities = 66/273 (24%), Positives = 122/273 (44%), Gaps = 35/273 (12%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
++++ + SG + VY V +A +K + + + ++ E+ +K +
Sbjct: 21 ELVQRVGSGTYGDVYKAR-----NVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHC 75
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
IV+Y S+ ++ ++++ MEYC GG L D + + L E +I + +
Sbjct: 76 N-IVAYFGSYLSRE-------KLWICMEYCGGGSLQDIYH--VTGPLSELQIAYVCRETL 125
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
QG+A +H +HRDIK N+LL+ + + KL DFG + + + F Y
Sbjct: 126 QGLAYLHTKGK--MHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY--- 180
Query: 203 KNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAI-LASKFE 260
+ PE+ + + ++ DIWA+G+ + P F+ + A+ L SK
Sbjct: 181 ------WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSN 234
Query: 261 FPAYPRYSDRVK------NLISVMLRVDPLKRP 287
F P+ D+ K N + + L +P KRP
Sbjct: 235 FQP-PKLKDKTKWSSTFHNFVKIALTKNPKKRP 266
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 70.5 bits (171), Expect = 9e-12
Identities = 61/194 (31%), Positives = 93/194 (47%), Gaps = 26/194 (13%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
V+L++EY SGG L +++ R +L E + + +Q+ V+ MH+ ++HRDIK EN
Sbjct: 121 VHLVIEYASGGELYTYVHER--GKLTEGDAKPLFAQIVSAVSHMHSRN--IVHRDIKAEN 176
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLP 222
V+ S + KL DFG S ++ + F + Y PE+ Y G
Sbjct: 177 VMFSSPNTVKLVDFG-FSCLVDREQMLRTF---------CGSPPYAAPELFQDTSYAG-- 224
Query: 223 IDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVM 278
E D+WALGV L+ TPF+ + + I A K++ P Y S LI M
Sbjct: 225 --ELVDVWALGVLLFFMLIGVTPFKAETVPDMKVLITAGKYQIPDY--VSLLATELIKSM 280
Query: 279 LRVDPLKRPNICQV 292
L+ D +R +I V
Sbjct: 281 LKTDTGQRADIDSV 294
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 70.1 bits (170), Expect = 1e-11
Identities = 80/370 (21%), Positives = 145/370 (38%), Gaps = 55/370 (14%)
Query: 18 GSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMK 77
G +VL+ L G F VY V+ + V K +V ++ + +
Sbjct: 408 GPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTT 467
Query: 78 ALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNI 137
A + + FIV S T + ++YL+ +Y SGG L F + + + R E
Sbjct: 468 ASKSSPFIVGLKFSFQTPT-------DLYLVTDYMSGGEL--FWHLQKEGRFSEDRAKFY 518
Query: 138 MSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYV 197
++++ + +H +++RD+K EN+LL N LCDFG ++ NT
Sbjct: 519 IAELVLALEHLH--DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNT------ 570
Query: 198 QYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAILA 256
T +Y PE++ G + D W+LGV +++ C +P F +N +
Sbjct: 571 -----FCGTTEYLAPELLLDETG--YTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQK 623
Query: 257 SKFEFPAYPR--YSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRM 314
F +PR S ++ + +L +P R +++ ++ P F+
Sbjct: 624 IAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHR---LGAIDDGRELRAHP-----FFADID 675
Query: 315 MDKQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQVVSNVQTPSKTASIQHLPYLHVSK 374
+ +Q ++ PP P +VS T + +++K
Sbjct: 676 WEALKQKKIPPP--------------------FKPHLVSETDTSNFDPEFTTASTSYMNK 715
Query: 375 SQPMVTQQDL 384
QPM+T L
Sbjct: 716 HQPMMTATPL 725
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 70.1 bits (170), Expect = 1e-11
Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 29/198 (14%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEF---EILNIMSQVSQGVAAMHALQPPLIHRDIK 161
VYL++E C G MN L+NR++ F E + M Q+ G+ +H+ ++HRD+
Sbjct: 85 VYLVLEMCHNGE----MNRYLKNRVKPFSENEARHFMHQIITGMLYLHS--HGILHRDLT 138
Query: 162 IENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID-LYRG 220
+ N+LL++N K+ DFG + + + E +Y T Y PE+ G
Sbjct: 139 LSNLLLTRNMNIKIADFGLATQL----KMPHEKHYTLCG-----TPNYISPEIATRSAHG 189
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLIS 276
L +SD+W+LG Y PF+ KN + ++ + +E P + S K+LI
Sbjct: 190 L----ESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTF--LSIEAKDLIH 243
Query: 277 VMLRVDPLKRPNICQVVE 294
+LR +P R ++ V++
Sbjct: 244 QLLRRNPADRLSLSSVLD 261
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 70.1 bits (170), Expect = 1e-11
Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 29/198 (14%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEF---EILNIMSQVSQGVAAMHALQPPLIHRDIK 161
VYL++E C G MN L+NR++ F E + M Q+ G+ +H+ ++HRD+
Sbjct: 85 VYLVLEMCHNGE----MNRYLKNRVKPFSENEARHFMHQIITGMLYLHS--HGILHRDLT 138
Query: 162 IENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID-LYRG 220
+ N+LL++N K+ DFG + + + E +Y T Y PE+ G
Sbjct: 139 LSNLLLTRNMNIKIADFGLATQL----KMPHEKHYTLCG-----TPNYISPEIATRSAHG 189
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLIS 276
L +SD+W+LG Y PF+ KN + ++ + +E P + S K+LI
Sbjct: 190 L----ESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTF--LSIEAKDLIH 243
Query: 277 VMLRVDPLKRPNICQVVE 294
+LR +P R ++ V++
Sbjct: 244 QLLRRNPADRLSLSSVLD 261
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 70.1 bits (170), Expect = 1e-11
Identities = 63/204 (30%), Positives = 100/204 (48%), Gaps = 33/204 (16%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
E+YL+ME GG L D + + N+ E + ++ ++ + +H+L ++HRDIK E
Sbjct: 116 ELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSLN--IVHRDIKPE 171
Query: 164 NVLLSKNHE----FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI-DLY 218
N+L+ ++ + KL DFG ++ ++ P T T Y PE+I +
Sbjct: 172 NLLVYEHQDGSKSLKLGDFG-LATIVDGPLYTV-----------CGTPTYVAPEIIAETG 219
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE------SAILASKFEFPA--YPRYSDR 270
GL K DIWA GV Y PF +G+ IL + +FP+ + SD
Sbjct: 220 YGL----KVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDS 275
Query: 271 VKNLISVMLRVDPLKRPNICQVVE 294
K LI++ML VD +R + QV+E
Sbjct: 276 AKELITMMLLVDVDQRFSAVQVLE 299
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 69.7 bits (169), Expect = 2e-11
Identities = 74/311 (23%), Positives = 144/311 (45%), Gaps = 37/311 (11%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
++L+ + +G + VY D V + +A +K V + +++L+ E+ ++ R +
Sbjct: 16 ELLQRVGAGTYGDVYKAR----DTVTSE-LAAVKIVKLDPGDDISSLQQEITILRECR-H 69
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
+V+YI S+ +++ ME+C GG L + + L+E +I + +
Sbjct: 70 PNVVAYIGSYLRND-------RLWICMEFCGGGSLQEIYHAT--GPLEERQIAYVCRERL 120
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
+G+ +H+ IHRDIK N+LL+ + KL DFG VSG + A + +++
Sbjct: 121 KGLHHLHSQGK--IHRDIKGANLLLTLQGDVKLADFG-VSGELTA-SVAKRRSFI----- 171
Query: 203 KNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAIL---ASK 258
T + PE+ + R +E D+WALG+ + P F + A++ S
Sbjct: 172 --GTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSS 229
Query: 259 FEFPAY---PRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMM 315
F+ P R++ + + + L +P KRP ++++ Q +P + L +++
Sbjct: 230 FQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRAL----LTQLL 285
Query: 316 DKQEQPRVSPP 326
DK P + P
Sbjct: 286 DKASDPHLGTP 296
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 69.7 bits (169), Expect = 2e-11
Identities = 54/211 (25%), Positives = 97/211 (45%), Gaps = 31/211 (14%)
Query: 93 ATKSPVNVGMYEVY-------LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGV 145
A P + ++EVY L++EY +GG + L + E +++ ++ Q+ +GV
Sbjct: 87 AKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGV 146
Query: 146 AAMHALQPPLIHRDIKIENVLLSKNH---EFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
+H Q ++H D+K +N+LLS + + K+ DFG + A E
Sbjct: 147 YYLH--QNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMG------- 197
Query: 203 KNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF--EKNGESAILASK-- 258
T +Y PE+++ PI +D+W +G+ Y +T+PF E N E+ + S+
Sbjct: 198 ---TPEYLAPEILNYD---PITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVN 251
Query: 259 --FEFPAYPRYSDRVKNLISVMLRVDPLKRP 287
+ + S + I +L +P KRP
Sbjct: 252 VDYSEETFSSVSQLATDFIQSLLVKNPEKRP 282
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 69.7 bits (169), Expect = 2e-11
Identities = 69/251 (27%), Positives = 105/251 (41%), Gaps = 40/251 (15%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
D +L + EV MK L + I+ TKS + YL+ EY G + D++
Sbjct: 57 DAVNLEKIYREVQIMKML-DHPHIIKLYQVMETKSML-------YLVTEYAKNGEIFDYL 108
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
RL E E Q+ V H + ++HRD+K EN+LL N K+ DFG
Sbjct: 109 ANH--GRLNESEARRKFWQILSAVDYCHGRK--IVHRDLKAENLLLDNNMNIKIADFGF- 163
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMID--LYRGLPIDEKSDIWALGVFL 236
N+ + + T + Y PE+ + Y G + DIW++GV L
Sbjct: 164 ------------GNFFKSGELLATWCGSPPYAAPEVFEGQQYEG----PQLDIWSMGVVL 207
Query: 237 YKTCYYTTPFEKNG----ESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
Y PF+ +L +F P + S+ ++LI ML +DP KR I Q+
Sbjct: 208 YVLVCGALPFDGPTLPILRQRVLEGRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQI 265
Query: 293 VEEVSRIQGIP 303
E + +P
Sbjct: 266 KEHKWMLIEVP 276
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 69.7 bits (169), Expect = 2e-11
Identities = 67/216 (31%), Positives = 99/216 (45%), Gaps = 34/216 (15%)
Query: 107 LLMEYCSGGGLIDFMNTRLQN--RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++MEY SGG L + R+ N R E E Q+ GV+ H++Q + HRD+K+EN
Sbjct: 93 IIMEYASGGELYE----RICNAGRFSEDEARFFFQQLLSGVSYCHSMQ--ICHRDLKLEN 146
Query: 165 VLL--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRG 220
LL S K+CDFG S S V+ + P++T T Y PE+ L R
Sbjct: 147 TLLDGSPAPRLKICDFGYSKSSVLHSQPKSTVG------------TPAYIAPEV--LLRQ 192
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGE--------SAILASKFEFPAYPRYSDRVK 272
+ +D+W+ GV LY PFE E IL+ K+ P R S
Sbjct: 193 EYDGKIADVWSCGVTLYVMLVGAYPFEDPEEPRDYRKTIQRILSVKYSIPDDIRISPECC 252
Query: 273 NLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKN 308
+LIS + DP R +I ++ ++ +P + N
Sbjct: 253 HLISRIFVADPATRISIPEIKTHSWFLKNLPADLMN 288
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 69.7 bits (169), Expect = 2e-11
Identities = 61/211 (28%), Positives = 97/211 (45%), Gaps = 34/211 (16%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL 166
++MEY SGG L D + T R E E Q+ GV H+LQ + HRD+K+EN L
Sbjct: 75 IVMEYASGGELFDRICTA--GRFSEAEARYFFQQLICGVDYCHSLQ--ICHRDLKLENTL 130
Query: 167 LSKNHE--FKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDL--YRG 220
L + K+CDFG S S ++ + P++T T Y PE++ Y G
Sbjct: 131 LDGSPAPLLKICDFGYSKSSILHSRPKSTVG------------TPAYIAPEVLSRREYDG 178
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGE--------SAILASKFEFPAYPRYSDRVK 272
+ +D+W+ GV LY PFE + I+A +++ P Y S K
Sbjct: 179 ----KHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECK 234
Query: 273 NLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
+L+S + + KR + ++ ++ +P
Sbjct: 235 HLLSRIFVTNSAKRITLKEIKNHPWYLKNLP 265
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 69.7 bits (169), Expect = 2e-11
Identities = 57/214 (26%), Positives = 93/214 (42%), Gaps = 27/214 (12%)
Query: 84 FIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQ 143
+IV Y DS K V + + YC GG + + E ++ M Q+
Sbjct: 73 YIVEYKDSWVEKDCVCI-------VTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLL 125
Query: 144 GVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMK 203
+ +H + ++HRD+K N+ L+K +E +L DFG + + +
Sbjct: 126 AIDYLHNNR--VLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDDLASSMVG-------- 175
Query: 204 NTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFE--- 260
T Y CPE++ +P KSDIW+LG +++ + F K + A L +K
Sbjct: 176 --TPNYMCPELL---ADIPYGYKSDIWSLGCCMFEVAAHQPAF-KAPDMAALINKINRSS 229
Query: 261 -FPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
P YS +K LI MLR +P RP +++
Sbjct: 230 LSPLPVMYSSSLKRLIKSMLRKNPEHRPTAAELL 263
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 69.7 bits (169), Expect = 2e-11
Identities = 83/305 (27%), Positives = 130/305 (42%), Gaps = 57/305 (18%)
Query: 5 QIEKYASGTILPVGSHQVKVLKYLASGGFAHV-YSVEISPPDPVCPDNVACLKRVVVPDK 63
+ + Y +G G+ K++K L G FA V ++ + V + V DK
Sbjct: 85 KFQSYVNGN----GNGVYKIIKTLGKGNFAKVKLAIHVPTGREVA---------IKVIDK 131
Query: 64 ASLNT-----LRAEVDSMKALRGNKFIVSY--IDSHATKSPVNVGMYEVYLLMEYCSGGG 116
LNT L EV MK L + + I+S T +YL+MEY S G
Sbjct: 132 TQLNTSARQKLYREVKIMKLLNHPNIVRLFQVIESERT----------LYLVMEYASRGE 181
Query: 117 LIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLC 176
L D + R++E + I Q+ + H+ ++HRD+K EN+LL ++ K+
Sbjct: 182 LFDHLVKN--GRMRERDARVIFRQLVSAIQYCHSKF--VVHRDLKAENLLLDQHMNIKIA 237
Query: 177 DFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGV 234
DFG NT + N Q + + Y PE+ Y G + D W+LGV
Sbjct: 238 DFGF--------GNTFDPN-AQLETFCG-SPPYAAPELFMGRKYAGPEV----DAWSLGV 283
Query: 235 FLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNIC 290
LY + PF+ K +L K+ P Y S +NL+ L ++P KR ++
Sbjct: 284 VLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYY--ISMDCENLMRKFLVLNPAKRTSLS 341
Query: 291 QVVEE 295
V+ +
Sbjct: 342 AVMSD 346
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 69.3 bits (168), Expect = 2e-11
Identities = 70/281 (24%), Positives = 120/281 (41%), Gaps = 34/281 (12%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
K L GGFA Y + + V + RV P + + E++ + L +K +
Sbjct: 86 KVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQRE--KIDKEIELHRILH-HKHV 142
Query: 86 VSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGV 145
V + K +Y+L+EYCS + + R L E E+ + Q+ G+
Sbjct: 143 VQFYHYFEDKE-------NIYILLEYCSRRSMAHILKAR--KVLTEPEVRYYLRQIVSGL 193
Query: 146 AAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
+H + ++HRD+K+ N +++ E K+ DFG + E + + I
Sbjct: 194 KYLH--EQEILHRDLKLGNFFINEAMELKVGDFGLAA-------RLEPLEHRRRTIC--G 242
Query: 206 TAQYRCPEMIDLY-RGLPIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFE 260
T Y PE+++ G +SDIWALG +Y PFE K I +++
Sbjct: 243 TPNYLSPEVLNKQGHGC----ESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYT 298
Query: 261 FPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQG 301
P+ K+LI+ ML +P RP++ ++ +QG
Sbjct: 299 MPS--SLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQG 337
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 69.3 bits (168), Expect = 2e-11
Identities = 71/269 (26%), Positives = 116/269 (42%), Gaps = 38/269 (14%)
Query: 24 VLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRV--VVPDKASLNTLRAEVDSMKALRG 81
VL+ + G F VY V LK + + + L L+ E++ M+ LR
Sbjct: 6 VLEMIGEGSFGRVYKGRRK-----YSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLR- 59
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
+ IV +DS T EV ++ +Y G F +L E ++ I +Q+
Sbjct: 60 HPNIVHMLDSFETDK-------EVVVVTDYAEGEL---FQILEDDGKLPEDQVQAIAAQL 109
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDI 201
+ +H+ + ++HRD+K +N+LL+K KLCDFG + NT ++
Sbjct: 110 VSALYYLHSHR--ILHRDMKPQNILLAKGGGIKLCDFGFARAM---STNTMVLTSIK--- 161
Query: 202 MKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNG----ESAILAS 257
T Y PE+++ P D +D+W++G LY+ T PF S IL
Sbjct: 162 ---GTPLYMSPELVE---ERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKD 215
Query: 258 KFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
+P+ S KN + +L DP +R
Sbjct: 216 PVRWPS--TISPCFKNFLQGLLTKDPRQR 242
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 69.3 bits (168), Expect = 2e-11
Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 32/237 (13%)
Query: 64 ASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
+SL L EV MK L + + K+ +YL+MEY S G + D++ +
Sbjct: 98 SSLQKLFREVRIMKGLNHPNIVKLFEVIETEKT--------LYLVMEYASAGEVFDYLVS 149
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
R++E E Q+ V H Q ++HRD+K EN+LL K+ DFG
Sbjct: 150 H--GRMKEKEARAKFRQIVSAVHYCH--QKNIVHRDLKAENLLLDAEANIKIADFGF--- 202
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID-EKSDIWALGVFLYKTCYY 242
+ EF + Y PE L++G D + DIW+LGV LY
Sbjct: 203 -------SNEFTLGSKLDTFCGSPPYAAPE---LFQGKKYDGPEVDIWSLGVILYTLVSG 252
Query: 243 TTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ PF+ K +L K+ P Y S ++++ L ++P KR + Q++++
Sbjct: 253 SLPFDGHNLKELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 525
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/178 (31%), Positives = 89/178 (49%), Gaps = 29/178 (16%)
Query: 60 VPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLID 119
VP L + E+ M+ + +K++V Y S+ S +++++MEYC G + D
Sbjct: 94 VPVDTDLQEIIKEISIMQQCK-SKYVVKYYGSYFKHS-------DLWIVMEYCGAGSISD 145
Query: 120 FMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG 179
M R + L E EI ++ +G+ +H L+ IHRDIK N+LL+ + KL DFG
Sbjct: 146 IMRAR-RKPLSEQEISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG 202
Query: 180 SVSGVI---RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
V+G + A RNT T + PE+I+ + D K+DIW+LG+
Sbjct: 203 -VAGQLTDTMAKRNT-----------VIGTPFWMAPEVIE---EIGYDTKADIWSLGI 245
>CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 640
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/178 (31%), Positives = 89/178 (49%), Gaps = 29/178 (16%)
Query: 60 VPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLID 119
VP L + E+ M+ + +K++V Y S+ S +++++MEYC G + D
Sbjct: 66 VPVDTDLQEIIKEISIMQQCK-SKYVVKYYGSYFKHS-------DLWIVMEYCGAGSISD 117
Query: 120 FMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG 179
M R + L E EI ++ +G+ +H L+ IHRDIK N+LL+ + KL DFG
Sbjct: 118 IMRAR-RKPLSEQEISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG 174
Query: 180 SVSGVI---RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
V+G + A RNT T + PE+I+ + D K+DIW+LG+
Sbjct: 175 -VAGQLTDTMAKRNT-----------VIGTPFWMAPEVIE---EIGYDTKADIWSLGI 217
>CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 421
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/178 (31%), Positives = 89/178 (49%), Gaps = 29/178 (16%)
Query: 60 VPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLID 119
VP L + E+ M+ + +K++V Y S+ S +++++MEYC G + D
Sbjct: 66 VPVDTDLQEIIKEISIMQQCK-SKYVVKYYGSYFKHS-------DLWIVMEYCGAGSISD 117
Query: 120 FMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG 179
M R + L E EI ++ +G+ +H L+ IHRDIK N+LL+ + KL DFG
Sbjct: 118 IMRAR-RKPLSEQEISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG 174
Query: 180 SVSGVI---RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
V+G + A RNT T + PE+I+ + D K+DIW+LG+
Sbjct: 175 -VAGQLTDTMAKRNT-----------VIGTPFWMAPEVIE---EIGYDTKADIWSLGI 217
>CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 523
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/178 (31%), Positives = 89/178 (49%), Gaps = 29/178 (16%)
Query: 60 VPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLID 119
VP L + E+ M+ + +K++V Y S+ S +++++MEYC G + D
Sbjct: 94 VPVDTDLQEIIKEISIMQQCK-SKYVVKYYGSYFKHS-------DLWIVMEYCGAGSISD 145
Query: 120 FMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG 179
M R + L E EI ++ +G+ +H L+ IHRDIK N+LL+ + KL DFG
Sbjct: 146 IMRAR-RKPLSEQEISAVLRDTLKGLQYLHDLKK--IHRDIKAGNILLNTDGIAKLADFG 202
Query: 180 SVSGVI---RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGV 234
V+G + A RNT T + PE+I+ + D K+DIW+LG+
Sbjct: 203 -VAGQLTDTMAKRNT-----------VIGTPFWMAPEVIE---EIGYDTKADIWSLGI 245
>At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 821
Score = 69.3 bits (168), Expect = 2e-11
Identities = 60/238 (25%), Positives = 112/238 (46%), Gaps = 33/238 (13%)
Query: 66 LNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN-TR 124
+N EV MK LR ++ A P N+ ++ EY S G L ++ +
Sbjct: 590 VNEFLREVAIMKRLRHPNIVLFM---GAVTQPPNLS-----IVTEYLSRGSLYRLLHKSG 641
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
+ +L E L++ V++G+ +H PP++HRD+K N+L+ K + K+CDF G+
Sbjct: 642 AREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDF----GL 697
Query: 185 IRAPRNTEEFNYVQYDIMKNT--TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYY 242
R +T + K+ T ++ PE++ R P +EKSD+++ GV L++
Sbjct: 698 SRLKAST-------FLSSKSAAGTPEWMAPEVL---RDEPSNEKSDVYSFGVILWELATL 747
Query: 243 TTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
P+ + ++A+ + E P + +V +I +P KRP+ +++
Sbjct: 748 QQPWGNLNPAQVVAAVGFKCKRLEIPR--NLNPQVAAIIEGCWTNEPWKRPSFATIMD 803
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 69.3 bits (168), Expect = 2e-11
Identities = 73/273 (26%), Positives = 111/273 (39%), Gaps = 33/273 (12%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
K L G F HVY D + V L + + + LR EV+ LR +
Sbjct: 23 KPLGRGKFGHVYLAREKRSDHIVALKV--LFKAQLQQSQVEHQLRREVEIQSHLRHPNIL 80
Query: 86 VSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGV 145
Y + K VYL++EY G L + + E ++ +++ +
Sbjct: 81 RLYGYFYDQK--------RVYLILEYAVRGEL--YKELQKCKYFSERRAATYVASLARAL 130
Query: 146 AAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
H +IHRDIK EN+L+ E K+ DFG + FN +
Sbjct: 131 IYCHGKH--VIHRDIKPENLLIGAQGELKIADFG---------WSVHTFNRRR---TMCG 176
Query: 206 TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEF 261
T Y PEM++ + D DIW+LG+ Y+ Y PFE S I+ +F
Sbjct: 177 TLDYLPPEMVE---SVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKF 233
Query: 262 PAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
P P S K+LIS ML + +R + +++E
Sbjct: 234 PPKPIVSSSAKDLISQMLVKESTQRLALHKLLE 266
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 69.3 bits (168), Expect = 2e-11
Identities = 61/227 (26%), Positives = 100/227 (43%), Gaps = 30/227 (13%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
+++++MEY GG +D M +E I I+ +V +G+ +H+ + +HRDIK
Sbjct: 83 KLWIIMEYLGGGSALDLMKA---GSFEEMHIGIILREVLKGLDYLHSERK--LHRDIKAA 137
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
NVLLS+ + KL DFG + F T + PE+I +
Sbjct: 138 NVLLSEQGDVKLADFGVAGQLTNTTSKRNTF---------VGTPFWMAPEVI---KQSQY 185
Query: 224 DEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFEFP------AYPRYSDRVKNLISV 277
D K+DIW+LG+ + P N E + F P Y+ K+ +
Sbjct: 186 DAKADIWSLGITAIELAKGEPP---NSELHPMRVLFLIPKNNPPQLTGSYTKSFKDFVEA 242
Query: 278 MLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMDKQEQPRVS 324
L DP RP +E+ + I KN YL+ ++D+ ++ +VS
Sbjct: 243 CLNKDPENRP----TAKELLKYPFIKKAKKNAYLIDLIDRFKKWKVS 285
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 68.9 bits (167), Expect = 3e-11
Identities = 57/197 (28%), Positives = 94/197 (46%), Gaps = 23/197 (11%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+Y++ME G L++F+ + Q L E + Q+S V H L ++HRD+K EN
Sbjct: 86 IYIIMELGVQGDLLEFI--KCQGALHEDVARKMFRQLSSAVKYCHDLD--IVHRDLKCEN 141
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGL 221
+LL K+ KL DFG +R I+ T +A Y PE++ + +
Sbjct: 142 LLLDKDFNIKLSDFGFSKRCLRDSNGR--------IILSKTFCGSAAYAAPEVL---QSI 190
Query: 222 PIDEK-SDIWALGVFLYKTCYYTTPFEKNGESAIL----ASKFEFPAYPRYSDRVKNLIS 276
P K DIW+LGV LY + P++ + +L + +FP + K+LI
Sbjct: 191 PYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIY 250
Query: 277 VMLRVDPLKRPNICQVV 293
ML+ D +R +I +++
Sbjct: 251 RMLQPDVSQRLHIDEIL 267
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 68.9 bits (167), Expect = 3e-11
Identities = 71/238 (29%), Positives = 104/238 (42%), Gaps = 34/238 (14%)
Query: 66 LNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRL 125
+ +R EV+ MK + + IVS D+ V++ +ME C GG L D + R
Sbjct: 99 IEDVRREVEIMKHMPRHPNIVSLKDAFEDDDAVHI-------VMELCEGGELFDRIVAR- 150
Query: 126 QNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSVS 182
E +M + + V H + ++HRD+K EN L + E K DFG
Sbjct: 151 -GHYTERAAAAVMKTILEVVQICH--KHGVMHRDLKPENFLFANKKETSALKAIDFGL-- 205
Query: 183 GVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYY 242
V P E FN + + Y PE++ G +D IW+ GV LY
Sbjct: 206 SVFFKPG--EGFNEIV------GSPYYMAPEVLRRNYGPEVD----IWSAGVILYILLCG 253
Query: 243 TTPF----EKNGESAILASKFEFPA--YPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
PF E+ AI+ S +F +PR S+ K+L+ ML DP KR + QV+E
Sbjct: 254 VPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSETAKDLVRKMLEPDPKKRLSAAQVLE 311
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 68.9 bits (167), Expect = 3e-11
Identities = 70/249 (28%), Positives = 105/249 (42%), Gaps = 35/249 (14%)
Query: 55 LKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSG 114
LKR ++ + ++ E+ M+ L G +V S+ + + V+L+ME C+G
Sbjct: 101 LKRKLISELGR-EDVKTEIQIMQHLSGQPNVVEIKGSYEDR-------HSVHLVMELCAG 152
Query: 115 GGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE-- 172
G L D Q E + + V H +IHRD+K EN L S E
Sbjct: 153 GELFD--RIIAQGHYSERAAAGTIKSIVDVVQICHL--NGVIHRDLKPENFLFSSKEENA 208
Query: 173 -FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWA 231
K+ DFG + + E + D++ + Y PE++ G I DIW+
Sbjct: 209 MLKVTDFGLSAFI--------EEGKIYKDVV--GSPYYVAPEVLRQSYGKEI----DIWS 254
Query: 232 LGVFLYKTCYYTTPFEKNGESA----ILASKFEF--PAYPRYSDRVKNLISVMLRVDPLK 285
GV LY PF + E IL K +F +P SD K+L+ ML DP +
Sbjct: 255 AGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSISDSAKDLVEKMLTEDPKR 314
Query: 286 RPNICQVVE 294
R QV+E
Sbjct: 315 RITAAQVLE 323
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 68.9 bits (167), Expect = 3e-11
Identities = 71/249 (28%), Positives = 108/249 (42%), Gaps = 35/249 (14%)
Query: 55 LKRVVVPDKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSG 114
LKR ++ K ++ E+ M+ L G IV ++ + ++L+ME C+G
Sbjct: 112 LKRKLI-SKQDKEDVKREIQIMQYLSGQPNIVEIKGAYEDRQ-------SIHLVMELCAG 163
Query: 115 GGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE-- 172
G L D + Q E I+ + V H + ++HRD+K EN LLS E
Sbjct: 164 GELFDRIIA--QGHYSERAAAGIIRSIVNVVQICHFMG--VVHRDLKPENFLLSSKEENA 219
Query: 173 -FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWA 231
K DFG + E V DI+ +A Y PE++ G I DIW+
Sbjct: 220 MLKATDFGLSVFI--------EEGKVYRDIV--GSAYYVAPEVLRRSYGKEI----DIWS 265
Query: 232 LGVFLYKTCYYTTPF----EKNGESAILASKFEFPA--YPRYSDRVKNLISVMLRVDPLK 285
GV LY PF EK ++ + +F + +P S+ K+L+ ML DP +
Sbjct: 266 AGVILYILLSGVPPFWAENEKGIFDEVIKGEIDFVSEPWPSISESAKDLVRKMLTKDPKR 325
Query: 286 RPNICQVVE 294
R QV+E
Sbjct: 326 RITAAQVLE 334
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 68.9 bits (167), Expect = 3e-11
Identities = 65/273 (23%), Positives = 120/273 (43%), Gaps = 32/273 (11%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSM 76
VG +V+K + G F VY V + V +++ + +K ++AE D +
Sbjct: 129 VGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKV--MRKDHIMEKNHAEYMKAERDIL 186
Query: 77 KALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILN 136
+ + FIV S TK Y +YL++++ +GG L F Q +E
Sbjct: 187 TKI-DHPFIVQLKYSFQTK-------YRLYLVLDFINGGHL--FFQLYHQGLFREDLARV 236
Query: 137 IMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNY 196
+++ V+ +H + ++HRD+K EN+L+ + L DFG +EF
Sbjct: 237 YTAEIVSAVSHLH--EKGIMHRDLKPENILMDTDGHVMLTDFGL----------AKEFEE 284
Query: 197 VQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF---EKNGESA 253
T +Y PE++ RG D+ +D W++G+ LY+ PF + +
Sbjct: 285 NTRSNSMCGTTEYMAPEIV---RGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQK 341
Query: 254 ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
I+ K + P + S+ ++ +L+ +P +R
Sbjct: 342 IVKDKIKLPQF--LSNEAHAILKGLLQKEPERR 372
>At2g42550 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 344
Score = 68.9 bits (167), Expect = 3e-11
Identities = 57/217 (26%), Positives = 100/217 (45%), Gaps = 18/217 (8%)
Query: 21 QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALR 80
+ + +K+L G + V V+ D A +K D N+L E+ + L
Sbjct: 4 KTEFVKFLRKGAYGSVDLVKYIKRDDNALPLYAAVKTAECED---YNSLEREIQILSKLE 60
Query: 81 GNKFIVSYIDSHATKSPVNVGMYEVY-LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMS 139
G + IV ++ + +VG + VY ++MEY + G L FM++ +L E I +
Sbjct: 61 GCRRIVQCYGNYTLEEDFDVGGFRVYKMVMEYAAAGSLFSFMDSYKDRKLPETMIKDFTR 120
Query: 140 QVSQGVAAMHALQPPLIHRDIKIENVLL---SKNHEFKLCDFGSVSGVIRAPRNTEEFNY 196
+ QG+ ++H L +H D+K +N+L+ +++E K+ DFGS V E +
Sbjct: 121 MILQGLVSVHRL--GYVHCDLKPDNLLVFPCRQSYELKISDFGSSRKV------GEYSDC 172
Query: 197 VQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALG 233
D+ T Y PE + R ++ D+W+LG
Sbjct: 173 WDVDLPFVGTPVYMSPESV---RSGVAEKALDLWSLG 206
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 68.9 bits (167), Expect = 3e-11
Identities = 62/249 (24%), Positives = 105/249 (41%), Gaps = 25/249 (10%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDK 63
P + GT + ++++ + G +A V VE+ + V +K+ +V D
Sbjct: 243 PPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKV--IKKALVTDD 300
Query: 64 ASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
++ ++ E + + F+V T S ++ ++E+ GG L+ M
Sbjct: 301 EDIDWVQTEKHVFETASNHPFLVGLHSCFQTPS-------RLFFVIEFVRGGDLMYHMQR 353
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
Q RL E +++S + +H + +I+RD+K++NVLL KL D+G
Sbjct: 354 --QRRLPEEHARFYAAEISLALNFLH--EKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKE 409
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYT 243
IR T F T Y PE++ RG D WALGV LY+
Sbjct: 410 GIRPGDTTSTF---------CGTPNYIAPEIL---RGEDYGFSVDWWALGVLLYEMLAGR 457
Query: 244 TPFEKNGES 252
+PF+ G S
Sbjct: 458 SPFDLAGAS 466
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 68.6 bits (166), Expect = 4e-11
Identities = 60/220 (27%), Positives = 97/220 (43%), Gaps = 24/220 (10%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
+++++L G + V SV+ P V + + + +R E+ M +G+
Sbjct: 39 EIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIR-ELKFMNFFKGH 97
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
K IV+ ID S G+Y L++Y L +++ +Q L EF I + Q+
Sbjct: 98 KNIVNLIDLEIVTSSPYDGLYCYQELIDY----DLAKVIHSSVQ--LSEFHIKYFLYQIL 151
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV------IRAPRNTEEFNY 196
G+ +H+ +IHRD+K N+L + N K+CDFG G+ + NY
Sbjct: 152 CGLKYIHSAD--VIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNY 209
Query: 197 VQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFL 236
V T YR PE+ L P + DIWA+G L
Sbjct: 210 V-------ATRWYRAPEL--LLSNQPYSKSVDIWAVGCIL 240
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 68.6 bits (166), Expect = 4e-11
Identities = 55/183 (30%), Positives = 82/183 (44%), Gaps = 22/183 (12%)
Query: 116 GLIDFMNT-RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFK 174
G ID + + + E E + QV + +H ++HRDIK ENV++ + K
Sbjct: 933 GSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLH--DQGIVHRDIKDENVIVDSHGFVK 990
Query: 175 LCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWAL 232
L DFGS + + P +D+ T Y PE++ Y+G P DIWAL
Sbjct: 991 LIDFGSAAYIKSGP----------FDVFVG-TMDYAAPEVLGGSSYKGKP----QDIWAL 1035
Query: 233 GVFLYKTCYYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
GV LY Y P+ E IL + F S+ +LI +L + KRP I ++
Sbjct: 1036 GVLLYTIIYKENPYYNIDE--ILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEI 1093
Query: 293 VEE 295
E+
Sbjct: 1094 YED 1096
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 68.6 bits (166), Expect = 4e-11
Identities = 77/275 (28%), Positives = 125/275 (45%), Gaps = 35/275 (12%)
Query: 27 YLASGGFAHVYS-VEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
++ SG F VY+ V + D + +K + + D T R+ VD + N+
Sbjct: 1042 FVRSGMFGDVYTGVNMETGD------LLAVKEIKLQDS---RTFRSTVDQIH----NEMT 1088
Query: 86 VSYIDSH---ATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNI-MSQV 141
V +H T V V +VY+ ME+C GG L D + R+++ +L + + Q+
Sbjct: 1089 VLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLL---AHGRIEDENVLKVYVVQL 1145
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNY--VQY 199
+G+A +H+ ++HRDIK N+LL K DFGS V +P E Y +Q
Sbjct: 1146 LEGLAYIHSQH--ILHRDIKPANILLDHRGMIKYSDFGSALYV--SPPTDPEVRYEDIQP 1201
Query: 200 DIMKNT-TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF-EKNGESAIL-- 255
++ T Y PE+I L DIW+LG + + +TP+ E + E AI+
Sbjct: 1202 ELQHLAGTPMYMAPEII-LGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYH 1260
Query: 256 ASKFEFPAYP---RYSDRVKNLISVMLRVDPLKRP 287
+ P+ P + S ++ I DP +RP
Sbjct: 1261 VAAMHTPSIPQNEKISSLARDFIEQCFERDPEQRP 1295
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 68.6 bits (166), Expect = 4e-11
Identities = 60/223 (26%), Positives = 104/223 (45%), Gaps = 29/223 (13%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
+++++MEY GG +D + L E +I I+ ++ +G+ +H+ + IHRDIK
Sbjct: 106 KLWIIMEYLGGGSALDLLEP---GPLDETQIATILREILKGLDYLHSEKK--IHRDIKAA 160
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRG 220
NVLLS++ E KL DFG V+G + I +NT T + PE+I +
Sbjct: 161 NVLLSEHGEVKLADFG-VAGQL-----------TDTQIKRNTFVGTPFWMAPEVI---KQ 205
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAI--LASKFEFPAYP-RYSDRVKNLISV 277
D K+DIW+LG+ + P + + L K P YS +K +
Sbjct: 206 SAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEA 265
Query: 278 MLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMDKQEQ 320
L +P RP ++++ ++ K YL ++D+ ++
Sbjct: 266 CLNKEPSFRPTAKELLKHKFILRNAK---KTSYLTELIDRYKR 305
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 68.6 bits (166), Expect = 4e-11
Identities = 65/242 (26%), Positives = 108/242 (43%), Gaps = 40/242 (16%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
D+ +L L EV +K + + SY +Y++ EYCS G L + +
Sbjct: 53 DRENLIKLEREVKIVKVIDHPHIVKSYEIMRVDNM--------LYIVSEYCSSGELYETL 104
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
+ R+ E S+ + VA +H+ ++HRD+K EN+LL KN K+ DFG
Sbjct: 105 IEK--GRVAENVARKWFSETASAVAYLHS--QGIVHRDLKAENILLGKNSNIKIIDFGF- 159
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMI--DLYRGLPIDEKSDIWALGVFL 236
N+ D + NT + Y PE++ + Y G+ K+DIW++GV L
Sbjct: 160 ------------SNFQTGDQLLNTWCGSPPYAAPELLLGNSYDGM----KADIWSMGVLL 203
Query: 237 YKTCYYTTPFEKNG----ESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
Y PF + + ++L+ + P + S + I ML ++P KR I V
Sbjct: 204 YILVAGGFPFPSDSVNKLKRSVLSGLVKIPYW--VSVECADFIRKMLVLNPGKRYTIQNV 261
Query: 293 VE 294
++
Sbjct: 262 LQ 263
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 68.6 bits (166), Expect = 4e-11
Identities = 72/240 (30%), Positives = 111/240 (46%), Gaps = 34/240 (14%)
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
K + +R EV M L G++ IV ++ + VN L+ME C GG L D +
Sbjct: 117 KDDIEDVRREVQIMHHLSGHRNIVDLKGAYEDRHSVN-------LIMELCEGGELFDRII 169
Query: 123 TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL-LSK--NHEFKLCDFG 179
++ E ++ Q+ V + H++ ++HRD+K EN L LSK N K DFG
Sbjct: 170 SK--GLYSERAAADLCRQMVMVVHSCHSMG--VMHRDLKPENFLFLSKDENSPLKATDFG 225
Query: 180 SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKT 239
V P + + D++ + A Y PE++ G ++DIW+ GV LY
Sbjct: 226 L--SVFFKPGDKFK------DLVGS--AYYVAPEVLKRNYG----PEADIWSAGVILYIL 271
Query: 240 CYYTTPFEKNGES----AILASKFEFPA--YPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
PF E+ AIL + +F A +P SD K+L+ ML+ DP R +V+
Sbjct: 272 LSGVPPFWGENETGIFDAILQGQLDFSADPWPALSDGAKDLVRKMLKYDPKDRLTAAEVL 331
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 68.6 bits (166), Expect = 4e-11
Identities = 53/194 (27%), Positives = 93/194 (47%), Gaps = 18/194 (9%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
+++++MEY +GG + D + + N L E I I + V +H IHRDIK
Sbjct: 85 KLWIIMEYMAGGSVADLLQSN--NPLDETSIACITRDLLHAVEYLH--NEGKIHRDIKAA 140
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
N+LLS+N + K+ DFG + + R + F T + PE+I G
Sbjct: 141 NILLSENGDVKVADFGVSAQLTRTISRRKTF---------VGTPFWMAPEVIQNSEG--Y 189
Query: 224 DEKSDIWALGVFLYKTCYYTTPF-EKNGESAILASKFEFPAY--PRYSDRVKNLISVMLR 280
+EK+DIW+LG+ + + P + + + E P +S +VK +S+ L+
Sbjct: 190 NEKADIWSLGITVIEMAKGEPPLADLHPMRVLFIIPRETPPQLDEHFSRQVKEFVSLCLK 249
Query: 281 VDPLKRPNICQVVE 294
P +RP+ ++++
Sbjct: 250 KAPAERPSAKELIK 263
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 68.6 bits (166), Expect = 4e-11
Identities = 76/287 (26%), Positives = 131/287 (45%), Gaps = 39/287 (13%)
Query: 17 VGSHQVKVLKYLASGGFAHV-YSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDS 75
VG++++ + L G FA V Y+ D + L R V + L+ E+ +
Sbjct: 16 VGNYEMG--RTLGEGSFAKVKYAKNTVTGDQAA---IKILDREKVFRHKMVEQLKREIST 70
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEIL 135
MK ++ + +V I+ A+K+ ++Y+++E +GG L D Q RL+E E
Sbjct: 71 MKLIK-HPNVVEIIEVMASKT-------KIYIVLELVNGGELFD--KIAQQGRLKEDEAR 120
Query: 136 NIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFN 195
Q+ V H+ + HRD+K EN++L N K+ DFG +S R
Sbjct: 121 RYFQQLINAVDYCHSRG--VYHRDLKPENLILDANGVLKVSDFG-LSAFSR--------- 168
Query: 196 YVQYDIMKNT---TAQYRCPEMID--LYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNG 250
V+ D + +T T Y PE++ Y G +D+W+ GV L+ PF++
Sbjct: 169 QVREDGLLHTACGTPNYVAPEVLSDKGYDG----AAADVWSCGVILFVLMAGYLPFDEPN 224
Query: 251 ESAIL--ASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
+ K EF P +S K +I +L +P+ R +I +++E+
Sbjct: 225 LMTLYKRICKAEFSCPPWFSQGAKRVIKRILEPNPITRISIAELLED 271
>7300915 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 252
Score = 68.6 bits (166), Expect = 4e-11
Identities = 48/156 (30%), Positives = 77/156 (48%), Gaps = 19/156 (12%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQP-PLIHRDIKIENV 165
LLME+ GG L F++ + + N Q++QG+A +H +QP +IHRDIK N
Sbjct: 81 LLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGMQPKAVIHRDIKPLNT 140
Query: 166 LL-SKNHEFKLCDFGSV----------SGVIR--APRNTEEFNYVQYDIMKNTTAQYRCP 212
LL K + K+CDFG+V +G R AP E F++ I+ N ++
Sbjct: 141 LLCEKGLKLKICDFGTVVDLSQSISCNAGTCRYKAPEVRELFDFKSNRIIINQPTGFQ-- 198
Query: 213 EMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEK 248
+ +G DEK D+++ + ++ PFE+
Sbjct: 199 ---KVLQGNKPDEKCDVYSWAITFWEILSRKEPFEQ 231
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 68.2 bits (165), Expect = 5e-11
Identities = 60/200 (30%), Positives = 95/200 (47%), Gaps = 33/200 (16%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL 166
+++EY GG ++ + RL+E + SQ+ GV +H+ L+HRD+K+EN+L
Sbjct: 127 IVLEYACGGEFYKYIQKK--RRLKEMNACRLFSQLISGVHYIHS--KGLVHRDLKLENLL 182
Query: 167 LSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQ--YRCPEMIDLYRGLPID 224
L KN + DFG V+ RN ++MK + Y PE++ P +
Sbjct: 183 LDKNENLVITDFGFVNEF--CSRN---------ELMKTSCGSPCYAAPELV--ISAEPYE 229
Query: 225 -EKSDIWALGVFLYKTCYYTTPFE---KNGESA--------ILASKFEFPAYPRYSDRVK 272
K+DIW+ GV LY P++ N E + I ++ +FP Y R
Sbjct: 230 ARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPR-- 287
Query: 273 NLISVMLRVDPLKRPNICQV 292
+L+ ML DP KR N+ Q+
Sbjct: 288 DLLRRMLVSDPKKRINLKQI 307
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 68.2 bits (165), Expect = 5e-11
Identities = 74/278 (26%), Positives = 119/278 (42%), Gaps = 27/278 (9%)
Query: 25 LKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTL-RAEVDSMKALRGNK 83
LK + G F VY V + V V K+V+V K +T+ ++ + +
Sbjct: 269 LKLIGKGTFGQVYLVRKKDTERVYAMKVLS-KKVIVRRKEVAHTVGERDILVQTSAADSP 327
Query: 84 FIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQ 143
FIV+ S T ++YL+ +Y +GG L F + + R E ++++
Sbjct: 328 FIVALRFSFQTPK-------DLYLVTDYMAGGEL--FWHLQKSVRFPEERAKFYIAELLL 378
Query: 144 GVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMK 203
+ A+H + +++RD+K EN+LL LCDFG + T F
Sbjct: 379 ALQALH--KRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTF--------- 427
Query: 204 NTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYK-TCYYTTPFEKNGESAILASKFEFP 262
T Y PE+I G D D W+LGV LY+ TC ++ + N + F
Sbjct: 428 CGTTDYLAPEVILDEAG--YDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKV 485
Query: 263 AYPR--YSDRVKNLISVMLRVDPLKRPNICQVVEEVSR 298
+PR S ++LI ++L +P R VEEV +
Sbjct: 486 RFPRGLLSVEARDLIKLLLNRNPKHRLGAHGDVEEVMK 523
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 68.2 bits (165), Expect = 5e-11
Identities = 48/198 (24%), Positives = 97/198 (48%), Gaps = 19/198 (9%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
++++++E+C GG +D + L L E +I + Q+ + + +H+ + +IHRD+K
Sbjct: 105 KLWIMIEFCPGGA-VDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKR--IIHRDLKAG 161
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPE--MIDLYRGL 221
NVL++ + +L DFG + ++ + + F Y + PE M + +
Sbjct: 162 NVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPY---------WMAPEVVMCETMKDT 212
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL--ASKFEFPAY---PRYSDRVKNLIS 276
P D K+DIW+LG+ L + P + +L +K + P ++S ++ +
Sbjct: 213 PYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLK 272
Query: 277 VMLRVDPLKRPNICQVVE 294
+ L +P RP+ Q++E
Sbjct: 273 IALDKNPETRPSAAQLLE 290
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 68.2 bits (165), Expect = 5e-11
Identities = 70/288 (24%), Positives = 123/288 (42%), Gaps = 46/288 (15%)
Query: 28 LASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIVS 87
+ SG A V + +P + VA + + + S++ L E+ +M + IVS
Sbjct: 23 IGSGATAVVQAAYCAPKK----EKVAIKRINLEKCQTSMDELLKEIQAMSQCH-HPNIVS 77
Query: 88 YIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN------TRLQNRLQEFEILNIMSQV 141
Y S K E++L+M+ SGG ++D + L E I I+ +V
Sbjct: 78 YYTSFVVKD-------ELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREV 130
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRA----PRNTEEFNYV 197
+G+ +H + IHRD+K N+LL ++ ++ DFG VS + RN +V
Sbjct: 131 LEGLEYLH--KNGQIHRDVKAGNILLGEDGSVQIADFG-VSAFLATGGDITRNKVRKTFV 187
Query: 198 QYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEK--------- 248
T + PE+++ RG D K+DIW+ G+ + P+ K
Sbjct: 188 -------GTPCWMAPEVMEQVRG--YDFKADIWSFGITAIELATGAAPYHKYPPMKVLML 238
Query: 249 ---NGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
N ++ + +Y + +IS+ L+ DP KRP +++
Sbjct: 239 TLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELL 286
>Hs4504357 [T] KOG0197 Tyrosine kinases
Length = 505
Score = 68.2 bits (165), Expect = 5e-11
Identities = 70/301 (23%), Positives = 133/301 (43%), Gaps = 37/301 (12%)
Query: 22 VKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRG 81
+K+ K L +G F V+ + V + + P S+ AE + MK L+
Sbjct: 241 LKLEKKLGAGQFGEVWMATYNKHTKVAV-------KTMKPGSMSVEAFLAEANVMKTLQH 293
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
+K + + + TK P+ Y++ E+ + G L+DF+ + ++ ++++ +Q+
Sbjct: 294 DKLVK--LHAVVTKEPI-------YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQI 344
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDI 201
++G+A + Q IHRD++ N+L+S + K+ DFG R E+ Y +
Sbjct: 345 AEGMAFIE--QRNYIHRDLRAANILVSASLVCKIADFG-------LARVIEDNEYTAREG 395
Query: 202 MKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYK-TCYYTTPFEKNGESAILASKFE 260
K ++ PE I+ + I KSD+W+ G+ L + Y P+ ++ +
Sbjct: 396 AK-FPIKWTAPEAIN-FGSFTI--KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
Query: 261 FPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMDKQEQ 320
PR + + L ++M+R RP EE + I + +FY Q+Q
Sbjct: 452 GYRMPRPENCPEELYNIMMRCWK-NRP------EERPTFEYIQSVLDDFYTATESQYQQQ 504
Query: 321 P 321
P
Sbjct: 505 P 505
>Hs13653487 [T] KOG0197 Tyrosine kinases
Length = 505
Score = 68.2 bits (165), Expect = 5e-11
Identities = 70/301 (23%), Positives = 133/301 (43%), Gaps = 37/301 (12%)
Query: 22 VKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRG 81
+K+ K L +G F V+ + V + + P S+ AE + MK L+
Sbjct: 241 LKLEKKLGAGQFGEVWMATYNKHTKVAV-------KTMKPGSMSVEAFLAEANVMKTLQH 293
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
+K + + + TK P+ Y++ E+ + G L+DF+ + ++ ++++ +Q+
Sbjct: 294 DKLVK--LHAVVTKEPI-------YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQI 344
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDI 201
++G+A + Q IHRD++ N+L+S + K+ DFG R E+ Y +
Sbjct: 345 AEGMAFIE--QRNYIHRDLRAANILVSASLVCKIADFG-------LARVIEDNEYTAREG 395
Query: 202 MKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYK-TCYYTTPFEKNGESAILASKFE 260
K ++ PE I+ + I KSD+W+ G+ L + Y P+ ++ +
Sbjct: 396 AK-FPIKWTAPEAIN-FGSFTI--KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
Query: 261 FPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMDKQEQ 320
PR + + L ++M+R RP EE + I + +FY Q+Q
Sbjct: 452 GYRMPRPENCPEELYNIMMRCWK-NRP------EERPTFEYIQSVLDDFYTATESQYQQQ 504
Query: 321 P 321
P
Sbjct: 505 P 505
>At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 575
Score = 68.2 bits (165), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 42/265 (15%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
++ E+ M + G IV S+ + ++++ME C GG L D ++ +++
Sbjct: 67 VKTEIQIMDHVSGQPNIVQIKGSYEDNN-------SIHIVMELCGGGELFDKIDALVKSH 119
Query: 129 --LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSVSG 183
E + I + V H+L ++HRD+K EN L S E K DFG S
Sbjct: 120 SYYSEKDAAGIFRSIVNAVKICHSLD--VVHRDLKPENFLFSSKDENAMLKAIDFGC-SV 176
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYT 243
I+ + E +Y Y PE+++ G ID IW+ GV LY
Sbjct: 177 YIKEGKTFERVVGSKY---------YIAPEVLEGSYGKEID----IWSAGVILYILLSGV 223
Query: 244 TPFEKNGESAILAS-------------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNIC 290
PF+ ES I+++ FE +P S + K+LI ML P +R +
Sbjct: 224 PPFQTGIESIIVSTLCIVDAEIKECRLDFESQPWPLISFKAKHLIGKMLTKKPKERISAA 283
Query: 291 QVVEEV-SRIQGIPCPIKNFYLLRM 314
V+E + + PI N L RM
Sbjct: 284 DVLEHPWMKSEAPDKPIDNVVLSRM 308
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 68.2 bits (165), Expect = 5e-11
Identities = 59/220 (26%), Positives = 102/220 (45%), Gaps = 27/220 (12%)
Query: 28 LASGGFAHVYS-VEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFIV 86
+ G + VY +++ D V V+ L+ +V D LNT+ E+D +K L +K IV
Sbjct: 26 IGKGAYGRVYKGLDLENGDFVAIKQVS-LENIVQED---LNTIMQEIDLLKNLN-HKNIV 80
Query: 87 SYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVA 146
Y+ S TK+ +++++EY G L + + E + ++QV +G+
Sbjct: 81 KYLGSSKTKT-------HLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLV 133
Query: 147 AMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTT 206
+H + +IHRDIK N+L +K KL DFG + + A NT Y
Sbjct: 134 YLH--EQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEADVNTHSVVGTPY------- 184
Query: 207 AQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF 246
+ PE+I++ + SDIW++G + + P+
Sbjct: 185 --WMAPEVIEM---SGVCAASDIWSVGCTVIELLTCVPPY 219
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 68.2 bits (165), Expect = 5e-11
Identities = 66/238 (27%), Positives = 103/238 (42%), Gaps = 33/238 (13%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
++ + EV ++AL G+K +V + D+ VY++ME C GG L+D + R
Sbjct: 167 AIEDVSREVKMLRALTGHKNLVQFYDAFEDDE-------NVYIVMELCKGGELLDKILQR 219
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSV 181
+ E + +M Q+ VA H ++HRD+K EN L S E K DFG
Sbjct: 220 -GGKYSEDDAKKVMVQILSVVAYCHL--QGVVHRDLKPENFLFSTKDETSPLKAIDFGLS 276
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
V + E N DI+ +A Y PE++ G ++D+W++GV Y
Sbjct: 277 DYV----KPDERLN----DIV--GSAYYVAPEVLHRTYG----TEADMWSIGVIAYILLC 322
Query: 242 YTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
+ PF ES I + FE +P S + + +L D KR Q +
Sbjct: 323 GSRPFWARTESGIFRAVLKAEPNFEEAPWPSLSPEAVDFVKRLLNKDYRKRLTAAQAL 380
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 68.2 bits (165), Expect = 5e-11
Identities = 76/300 (25%), Positives = 133/300 (44%), Gaps = 43/300 (14%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVE-ISPPDPVCPDNVACLKRVVVPD 62
P+ + G+IL + ++ K L G FA VY I + V + + + +
Sbjct: 42 PRSPRTPQGSIL---MDKYEIGKLLGHGSFAKVYLARNIHSGEDVA---IKVIDKEKIVK 95
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
++ E+ ++ +R + +IV ++ ATK+ ++Y++MEY GG L N
Sbjct: 96 SGLAGHIKREISILRRVR-HPYIVHLLEVMATKT-------KIYIVMEYVRGGELY---N 144
Query: 123 TRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG--S 180
T + RL+E Q+ VA H+ + HRD+K+EN+LL K+ DFG
Sbjct: 145 TVARGRLREGTARRYFQQLISSVAFCHSRG--VYHRDLKLENLLLDDKGNVKVSDFGLSV 202
Query: 181 VSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDL--YRGLPIDEKSDIWALGVFLYK 238
VS ++ + F T Y PE++ Y G K+DIW+ GV L+
Sbjct: 203 VSEQLKQEGICQTF---------CGTPAYLAPEVLTRKGYEG----AKADIWSCGVILFV 249
Query: 239 TCYYTTPFEKNG----ESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
PF+ + I +F+ P + +S + L++ ML +P R I ++++
Sbjct: 250 LMAGYLPFDDKNILVMYTKIYKGQFKCPKW--FSPELARLVTRMLDTNPDTRITIPEIMK 307
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 68.2 bits (165), Expect = 5e-11
Identities = 67/235 (28%), Positives = 100/235 (42%), Gaps = 34/235 (14%)
Query: 69 LRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR 128
+R EV+ M+ L + IVS+ ++ K V YL+ME C GG L D + +R
Sbjct: 111 VRREVEIMRCLPKHPNIVSFKEAFEDKDAV-------YLVMEICEGGELFDRIVSR--GH 161
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDFGSVSGVI 185
E ++ + + V H + +IHRD+K EN L S E K DFG +
Sbjct: 162 YTERAAASVAKTILEVVKVCH--EHGVIHRDLKPENFLFSNGTETAQLKAIDFG--LSIF 217
Query: 186 RAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
P + FN + + Y PE++ G I D+W+ GV LY P
Sbjct: 218 FKP--AQRFNEIV------GSPYYMAPEVLRRNYGPEI----DVWSAGVILYILLCGVPP 265
Query: 246 FEKNGESAILAS------KFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
F E I + FE +P+ S K L+ ML +P R + +V+E
Sbjct: 266 FWAETEEGIAHAIVRGNIDFERDPWPKVSHEAKELVKNMLDANPYSRLTVQEVLE 320
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 67.8 bits (164), Expect = 6e-11
Identities = 58/229 (25%), Positives = 99/229 (42%), Gaps = 27/229 (11%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
D + ++ E+ + +L+ I Y S+ + ++++ME+C+GG L +
Sbjct: 59 DSDEVEDVQREIQFLASLKQISNITRYYGSYLKDT-------SLWIIMEHCAGGSLRSLL 111
Query: 122 NTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSV 181
++ E I IM ++ + +H + +IHRDIK NVL++ KLCDFG
Sbjct: 112 RP---GKIDEKYIGVIMRELLVALKCIH--KDNVIHRDIKAANVLITNEGNVKLCDFGVA 166
Query: 182 SGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCY 241
+ V + + Y + PE+I G+ D K DIW+LG+ Y+
Sbjct: 167 AQVNQTSLRRQTMAGTPY---------WMAPEVI--MEGVYYDTKVDIWSLGITTYEIAT 215
Query: 242 YTTPF----EKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
P+ I+ SK YS +K I++ L DP +R
Sbjct: 216 GNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKER 264
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 560
Score = 67.8 bits (164), Expect = 6e-11
Identities = 54/212 (25%), Positives = 89/212 (41%), Gaps = 26/212 (12%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILN------IMSQVSQGVAAMHALQPPLIH 157
+VYL++EYCS G + +++ + IL ++ V G+ +H+ + H
Sbjct: 130 KVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEYLHS--QGITH 187
Query: 158 RDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDL 217
RDIK N+L+S N K+ DFG N + + T + PE+
Sbjct: 188 RDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCST 247
Query: 218 YRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGE----SAILASKFEFPAY--------- 264
+ DIW+LGV +Y + PF N +I+ EFP+Y
Sbjct: 248 EKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEMLNGATS 307
Query: 265 ----PRYSDRVKNLISVMLRVDPLKRPNICQV 292
Y+D K+L+ +L+ DP KR + +
Sbjct: 308 GITMEEYTD-AKDLLKKLLQKDPDKRIKLADI 338
>Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 579
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/205 (28%), Positives = 101/205 (48%), Gaps = 27/205 (13%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMS---QVSQGVAAMHALQP-PLIHRDI 160
V L+MEY GG L + ++ L + + MS Q SQGVA +H++QP LIHRD+
Sbjct: 100 VCLVMEYAEGGSLYNVLHGA--EPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDL 157
Query: 161 KIENVLL-SKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
K N+LL + K+CDFG+ + N + +A + PE ++
Sbjct: 158 KPPNLLLVAGGTVLKICDFGTACDIQTHMTNNK------------GSAAWMAPE---VFE 202
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA--ILASKFEFPAYPRYSDRVKNLISV 277
G EK D+++ G+ L++ PF++ G A I+ + P + K + S+
Sbjct: 203 GSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESL 262
Query: 278 MLRV---DPLKRPNICQVVEEVSRI 299
M R DP +RP++ ++V+ ++ +
Sbjct: 263 MTRCWSKDPSQRPSMEEIVKIMTHL 287
>Hs21735566 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 491
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/205 (28%), Positives = 101/205 (48%), Gaps = 27/205 (13%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMS---QVSQGVAAMHALQP-PLIHRDI 160
V L+MEY GG L + ++ L + + MS Q SQGVA +H++QP LIHRD+
Sbjct: 100 VCLVMEYAEGGSLYNVLHGA--EPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDL 157
Query: 161 KIENVLL-SKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
K N+LL + K+CDFG+ + N + +A + PE ++
Sbjct: 158 KPPNLLLVAGGTVLKICDFGTACDIQTHMTNNK------------GSAAWMAPE---VFE 202
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA--ILASKFEFPAYPRYSDRVKNLISV 277
G EK D+++ G+ L++ PF++ G A I+ + P + K + S+
Sbjct: 203 GSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESL 262
Query: 278 MLRV---DPLKRPNICQVVEEVSRI 299
M R DP +RP++ ++V+ ++ +
Sbjct: 263 MTRCWSKDPSQRPSMEEIVKIMTHL 287
>Hs21735564 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 518
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/205 (28%), Positives = 101/205 (48%), Gaps = 27/205 (13%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMS---QVSQGVAAMHALQP-PLIHRDI 160
V L+MEY GG L + ++ L + + MS Q SQGVA +H++QP LIHRD+
Sbjct: 100 VCLVMEYAEGGSLYNVLHGA--EPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDL 157
Query: 161 KIENVLL-SKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
K N+LL + K+CDFG+ + N + +A + PE ++
Sbjct: 158 KPPNLLLVAGGTVLKICDFGTACDIQTHMTNNK------------GSAAWMAPE---VFE 202
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA--ILASKFEFPAYPRYSDRVKNLISV 277
G EK D+++ G+ L++ PF++ G A I+ + P + K + S+
Sbjct: 203 GSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESL 262
Query: 278 MLRV---DPLKRPNICQVVEEVSRI 299
M R DP +RP++ ++V+ ++ +
Sbjct: 263 MTRCWSKDPSQRPSMEEIVKIMTHL 287
>Hs21735562 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 606
Score = 67.8 bits (164), Expect = 6e-11
Identities = 59/205 (28%), Positives = 101/205 (48%), Gaps = 27/205 (13%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMS---QVSQGVAAMHALQP-PLIHRDI 160
V L+MEY GG L + ++ L + + MS Q SQGVA +H++QP LIHRD+
Sbjct: 100 VCLVMEYAEGGSLYNVLHGA--EPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDL 157
Query: 161 KIENVLL-SKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
K N+LL + K+CDFG+ + N + +A + PE ++
Sbjct: 158 KPPNLLLVAGGTVLKICDFGTACDIQTHMTNNK------------GSAAWMAPE---VFE 202
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA--ILASKFEFPAYPRYSDRVKNLISV 277
G EK D+++ G+ L++ PF++ G A I+ + P + K + S+
Sbjct: 203 GSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESL 262
Query: 278 MLRV---DPLKRPNICQVVEEVSRI 299
M R DP +RP++ ++V+ ++ +
Sbjct: 263 MTRCWSKDPSQRPSMEEIVKIMTHL 287
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 67.8 bits (164), Expect = 6e-11
Identities = 66/256 (25%), Positives = 109/256 (41%), Gaps = 49/256 (19%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
SL L EV MK L + + K+ +YL+MEY SGG + D++
Sbjct: 96 SLQKLFREVRIMKILNHPNIVKLFEVIETEKT--------LYLIMEYASGGEVFDYLVAH 147
Query: 125 LQNRLQE--------------------FEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+ + +E F++L++M A + Q ++HRD+K EN
Sbjct: 148 GKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVS-AVQYCHQKRIVHRDLKAEN 206
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPID 224
+LL + K+ DFG + EF + Y PE L++G D
Sbjct: 207 LLLDADMNIKIADFGF----------SNEFTVGGKLDTFCGSPPYAAPE---LFQGKKYD 253
Query: 225 -EKSDIWALGVFLYKTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVML 279
+ D+W+LGV LY + PF+ K +L K+ P Y S +NL+ L
Sbjct: 254 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY--MSTDCENLLKRFL 311
Query: 280 RVDPLKRPNICQVVEE 295
++P+KR + Q++++
Sbjct: 312 VLNPIKRGTLEQIMKD 327
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 67.8 bits (164), Expect = 6e-11
Identities = 60/203 (29%), Positives = 96/203 (46%), Gaps = 31/203 (15%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
E+YL++EY GG L D + + + E + ++ + + + MH ++HRD+K E
Sbjct: 354 EIYLILEYVQGGDLFDAIIESV--KFPEPDAALMIMDLCKALVHMH--DKSIVHRDLKPE 409
Query: 164 NVLLSKNHE----FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYR 219
N+L+ +N + KL DFG V+R T Y PE++ +
Sbjct: 410 NLLVQRNEDKSTTLKLADFGLAKHVVRP------------IFTVCGTPTYVAPEILS-EK 456
Query: 220 GLPIDEKSDIWALGVFLYKTCYYTTPF---EKNGE---SAILASKFEF--PAYPRYSDRV 271
G ++ D+WA GV LY PF E++ + + I FEF P + SD
Sbjct: 457 GYGLE--VDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAA 514
Query: 272 KNLISVMLRVDPLKRPNICQVVE 294
K+L+S +L VDP KR QV++
Sbjct: 515 KDLVSRLLVVDPKKRYTAHQVLQ 537
>CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 1228
Score = 67.8 bits (164), Expect = 6e-11
Identities = 67/283 (23%), Positives = 123/283 (42%), Gaps = 44/283 (15%)
Query: 24 VLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNK 83
++ L G F V +S DP A K + + + L E++ + +G+
Sbjct: 36 IIGELGDGAFGKVEKA-VSRTDPKL---FAASKSIEIQEGEELEDFLVEIEILSECKGH- 90
Query: 84 FIVSYIDSHATKSPVNVGMYEVY-------LLMEYCSGGGLIDFMNTRLQNRLQEFEILN 136
PV +G+Y Y +L+E+C GGG +D + L + L+E +I
Sbjct: 91 -------------PVMLGLYSTYFFENKLTMLLEFC-GGGAVDNIIVELGHVLKEDQIRY 136
Query: 137 IMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNY 196
I V + +H+ +IHRD+K N+LL+++ + +L DFG VS +++ R + +
Sbjct: 137 IGYYVCDALKWLHSQN--VIHRDLKAGNILLTQDGQVRLADFG-VSAKLKSEREKRD-TF 192
Query: 197 VQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAI 254
+ T + PE++ + ++ P D SDIW+ G+ L + P +
Sbjct: 193 I-------GTPYWMAPEVMACETFKDQPYDCISDIWSFGITLIEMAQGEPPHSDVSVMRV 245
Query: 255 L--ASKFEFPAYPRYSDRVKNLISVMLRV---DPLKRPNICQV 292
+ K E P + S ++ ++ R DP RP ++
Sbjct: 246 IIKVQKSEPPTLLQPSHWTRSFSDILTRCLVKDPRNRPPAAEI 288
>At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 736
Score = 67.8 bits (164), Expect = 6e-11
Identities = 55/238 (23%), Positives = 111/238 (46%), Gaps = 29/238 (12%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
+L + E++ MK LR + ++ ++ + T+ + ++MEY G L ++
Sbjct: 506 TLTECKKEINIMKKLR-HPNVLLFMGAVCTEE-------KSAIIMEYMPRGSLFKILHNT 557
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGV 184
Q L + L + V++G+ +H PP++HRD+K N+L+ KN K+ DFG
Sbjct: 558 NQP-LDKKRRLRMALDVARGMNYLHRRNPPIVHRDLKSSNLLVDKNWNVKVGDFGLSKWK 616
Query: 185 IRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTT 244
+T+ T Q+ PE++ R P +EK D+++ GV L++
Sbjct: 617 NATFLSTKS---------GKGTPQWMAPEVL---RSEPSNEKCDVFSFGVILWELMTTLV 664
Query: 245 PFEK------NGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV 296
P+++ G + + + P + R+ ++I + DP KRP+ +++ ++
Sbjct: 665 PWDRLNSIQVVGVVGFMDRRLDLP--EGLNPRIASIIQDCWQTDPAKRPSFEELISQM 720
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 67.8 bits (164), Expect = 6e-11
Identities = 54/194 (27%), Positives = 91/194 (46%), Gaps = 18/194 (9%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
+++++MEY +GG + D + N L E I I + V +HA IHRDIK
Sbjct: 412 KLWIIMEYMAGGSVADLLQPG--NPLDEISIACITRDLLHAVEYLHA--EGKIHRDIKAA 467
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
N+LLS+N + K+ DFG + + R + F T + PE+I G
Sbjct: 468 NILLSENGDVKVADFGVSAQLTRTISRRKTF---------VGTPFWMAPEVIQNSEG--Y 516
Query: 224 DEKSDIWALGVFLYKTCYYTTPF-EKNGESAILASKFEFPAY--PRYSDRVKNLISVMLR 280
+EK+DIW+LG+ + + P + + + E P +S +K +S L+
Sbjct: 517 NEKADIWSLGITMIEMAKGEPPLADLHPMRVLFIIPRESPPQLDEHFSRPLKEFVSFCLK 576
Query: 281 VDPLKRPNICQVVE 294
P +RPN ++++
Sbjct: 577 KAPAERPNAKELLK 590
>7293601 [T] KOG0577 Serine/threonine protein kinase
Length = 1039
Score = 67.8 bits (164), Expect = 6e-11
Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 21/192 (10%)
Query: 106 YLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENV 165
+L+MEYC G D + + L E EI I V G++ +H+L IHRDIK N+
Sbjct: 101 WLVMEYCVGSAS-DIIEVH-KKPLHEDEIAAICLGVLSGLSYLHSLGR--IHRDIKAGNI 156
Query: 166 LLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDE 225
LL+ N KL DFGS + I+ P N ++V T + PE+I D
Sbjct: 157 LLTDNGVVKLADFGSAA--IKCPAN----SFV-------GTPYWMAPEVILAMDEGQYDG 203
Query: 226 KSDIWALGVFLYKTCYYTTP-FEKNGESAIL-ASKFEFPAYPR--YSDRVKNLISVMLRV 281
K D+W+LG+ + P F N SA+ ++ E P P+ +SD + + + L+
Sbjct: 204 KVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKNDWSDAFCSFVELCLKK 263
Query: 282 DPLKRPNICQVV 293
P +RP+ +++
Sbjct: 264 MPAERPSSAKLL 275
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 67.4 bits (163), Expect = 8e-11
Identities = 77/329 (23%), Positives = 126/329 (37%), Gaps = 72/329 (21%)
Query: 65 SLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTR 124
S L E+ +K L+ + Y S VYL+MEYC+GG L D+++
Sbjct: 56 SQTLLGKEIKILKELKHENIVALYDFQEMANS--------VYLVMEYCNGGDLADYLHA- 106
Query: 125 LQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS---------KNHEFKL 175
L E I + Q++ + +H+ +IHRD+K +N+LLS + K+
Sbjct: 107 -MRTLSEDTIRLFLQQIAGAMRLLHS--KGIIHRDLKPQNILLSNPAGRRANPNSIRVKI 163
Query: 176 CDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGLPIDEKSDIWAL 232
DFG Y+Q ++M T + Y PE+I D K+D+W++
Sbjct: 164 ADFGFA-------------RYLQSNMMAATLCGSPMYMAPEVI---MSQHYDGKADLWSI 207
Query: 233 GVFLYKTCYYTTPFEKNGESAIL----ASKFEFPAYPR-YSDRVKNLISVMLRVDPLKRP 287
G +Y+ PF+ + + +K P PR S ++ L+ +L+ + R
Sbjct: 208 GTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRM 267
Query: 288 NICQVVEEVSRIQGIPCPIKNFYLLRMMDKQEQPRVSPPPHVPQ--MXXXXXXXXXXXXQ 345
+ F+ +D R SPP VP
Sbjct: 268 D-----------------FDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTS 310
Query: 346 HL--PP------QVVSNVQTPSKTASIQH 366
HL PP Q+ + +P+ TA H
Sbjct: 311 HLASPPSLGEMQQLQKTLASPADTAGFLH 339
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 67.4 bits (163), Expect = 8e-11
Identities = 70/314 (22%), Positives = 136/314 (43%), Gaps = 44/314 (14%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGN 82
++++ + SG + VY V +A +K + + ++ E+ MK + +
Sbjct: 17 ELIQRIGSGTYGDVYKAR-----NVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCK-H 70
Query: 83 KFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVS 142
IV+Y S+ + ++++ ME+C GG L D + + L E +I + +
Sbjct: 71 PNIVAYFGSYLRRD-------KLWICMEFCGGGSLQDIYH--VTGPLSELQIAYVSRETL 121
Query: 143 QGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
QG+ +H+ +HRDIK N+LL+ N KL DFG + + + F Y
Sbjct: 122 QGLYYLHSKGK--MHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPY--- 176
Query: 203 KNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAI-LASKFE 260
+ PE+ + R ++ D+WA+G+ + P F+ + A+ L +K
Sbjct: 177 ------WMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSN 230
Query: 261 FPAYPRYSDRVK------NLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRM 314
F P+ D++K + + + L +P KRP ++++ P +L R
Sbjct: 231 FQP-PKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQH---------PFVTQHLTRS 280
Query: 315 MDKQEQPRVSPPPH 328
+ + +V+ P H
Sbjct: 281 LAIELLDKVNNPDH 294
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 67.4 bits (163), Expect = 8e-11
Identities = 55/195 (28%), Positives = 93/195 (47%), Gaps = 17/195 (8%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
+VY++ME G L++ + TR L E E Q+S + H L ++HRD+K +
Sbjct: 85 KVYIVMELAVQGDLLELIKTR--GALHEDEARKKFHQLSLAIKYCHDLD--VVHRDLKCD 140
Query: 164 NVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPI 223
N+LL K+ KL DF +R ++ + + Y PE++ +G+P
Sbjct: 141 NLLLDKDFNIKLSDFSFSKRCLR-----DDSGRMALSKTFCGSPAYAAPEVL---QGIPY 192
Query: 224 DEK-SDIWALGVFLYKTCYYTTPFEKNGESAILASKFE----FPAYPRYSDRVKNLISVM 278
K DIW+LGV LY + P++ + +L + E FP + K+LI M
Sbjct: 193 QPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHM 252
Query: 279 LRVDPLKRPNICQVV 293
L+ D +R +I +++
Sbjct: 253 LQPDVNRRLHIDEIL 267
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 67.4 bits (163), Expect = 8e-11
Identities = 71/265 (26%), Positives = 118/265 (43%), Gaps = 33/265 (12%)
Query: 27 YLASGGFAHVYSVEISPPDPVCPDNVAC--LKRVVVPDKASLNTLRAEVDSMKALRGNKF 84
+L GGFAH + E D C D +A + +V++ + L EV+ + L ++
Sbjct: 40 FLGEGGFAHCF--EFRKLD--CNDRLAVKVVPKVILLKSTAREKLTREVEIHRQL-SHRN 94
Query: 85 IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQG 144
IV + H + NV Y +E CS L++ R L E E QV++G
Sbjct: 95 IVQF--HHFFEDSQNV-----YFTLELCSKNSLMELNKQR--GPLTEHEARFYTIQVAEG 145
Query: 145 VAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKN 204
V +H LQ +IHRD+K+ N+ L+++ + K+ DFG + + + + +
Sbjct: 146 VKHLHNLQ--IIHRDLKLGNLFLNEHLQVKIGDFGLATFCEKNEKK----------MTRG 193
Query: 205 TTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKN--GESAILASKFEFP 262
T Y PE+++ G + DIWA+G LY + + PFE E+ + ++
Sbjct: 194 GTPNYIAPEVLN-ETGHAFE--VDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNNDYV 250
Query: 263 AYPRYSDRVKNLISVMLRVDPLKRP 287
S LI +L P +RP
Sbjct: 251 VPENASPTANRLIRSLLDPVPDRRP 275
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 67.4 bits (163), Expect = 8e-11
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 42/281 (14%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLK----RVVVPDKASLNTLRAEVDSMKALRG 81
K L G F + Y V I P+ D VA + ++V+P ++ ++ EV + AL G
Sbjct: 66 KLLGHGQFGYTY-VAIHRPNG---DRVAVKRLDKSKMVLP--IAVEDVKREVQILIALSG 119
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
++ +V + ++ VY++ME C GG L+D + ++ NR E + ++ Q+
Sbjct: 120 HENVVQFHNAFEDDD-------YVYIVMELCEGGELLDRILSKKGNRYSEKDAAVVVRQM 172
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSK---NHEFKLCDFGSVSGVIRAPRNTEEFNYVQ 198
+ H L+HRD+K EN L + K DFG +S I+ +
Sbjct: 173 LKVAGECHL--HGLVHRDMKPENFLFKSAQLDSPLKATDFG-LSDFIKPGKRF------- 222
Query: 199 YDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAI---- 254
+DI+ +A Y PE++ G +SD+W++GV Y PF E I
Sbjct: 223 HDIV--GSAYYVAPEVLKRRSG----PESDVWSIGVITYILLCGRRPFWDRTEDGIFKEV 276
Query: 255 LASKFEFPAYP--RYSDRVKNLISVMLRVDPLKRPNICQVV 293
L +K +F P SD K+ + +L DP R Q +
Sbjct: 277 LRNKPDFSRKPWATISDSAKDFVKKLLVKDPRARLTAAQAL 317
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 67.4 bits (163), Expect = 8e-11
Identities = 79/274 (28%), Positives = 122/274 (43%), Gaps = 41/274 (14%)
Query: 26 KYLASGGFAHVY-SVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKF 84
+ L G FA VY EI + C K V+ + ++ E+ MK +R +
Sbjct: 16 RLLGKGTFAKVYYGKEIIGGE--CVAIKVINKDQVMKRPGMMEQIKREISIMKLVR-HPN 72
Query: 85 IVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQG 144
IV + ATK+ +++ +ME+ GG L ++ + +L E Q+
Sbjct: 73 IVELKEVMATKT-------KIFFVMEFVKGGELFCKIS---KGKLHEDAARRYFQQLISA 122
Query: 145 VAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKN 204
V H+ + HRD+K EN+LL +N + K+ DF G+ P + D + +
Sbjct: 123 VDYCHSRG--VSHRDLKPENLLLDENGDLKISDF----GLSALPEQ------ILQDGLLH 170
Query: 205 T---TAQYRCPEMIDL--YRGLPIDEKSDIWALGVFLYKTCYYTTPFE----KNGESAIL 255
T T Y PE++ Y G K+DIW+ GV LY PF+ N I
Sbjct: 171 TQCGTPAYVAPEVLKKKGYDG----AKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIF 226
Query: 256 ASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNI 289
+ FEFP P +S + LIS +L VDP +R +I
Sbjct: 227 RADFEFP--PWFSPEARRLISKLLVVDPDRRISI 258
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 67.4 bits (163), Expect = 8e-11
Identities = 66/273 (24%), Positives = 116/273 (42%), Gaps = 41/273 (15%)
Query: 23 KVLKYLASGGFAHVYSVE-ISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRG 81
+V L GGFA VY + V + + + ++ N +R EV+ L+
Sbjct: 15 EVQHLLGKGGFATVYKARCLHTHQDVA---IKMIDKKLIQGTGLTNRVRQEVEIHSRLKH 71
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
+ Y VYL++E G L +MN + E E +I+ QV
Sbjct: 72 PSVLQLYTFFQDANY--------VYLVLELAHNGELHRYMN-HIARPFTETEAASILKQV 122
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEF----NYV 197
G+ +H+ ++HRDI + N+LLS+ K+ DFG + + R NY+
Sbjct: 123 VAGLLYLHSHN--IMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYI 180
Query: 198 QYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESA---- 253
+++ T+ GLP +D+W++G LY PFE + +
Sbjct: 181 SPEVVSRTS------------HGLP----ADVWSVGCMLYTLLVGRPPFETDAVQSTLNK 224
Query: 254 ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKR 286
++ S++ PA+ Y ++LI+ +L+ P +R
Sbjct: 225 VVMSEYIMPAHLSY--EAQDLINKLLKKLPHER 255
>7290629 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 359
Score = 67.4 bits (163), Expect = 8e-11
Identities = 67/250 (26%), Positives = 103/250 (40%), Gaps = 35/250 (14%)
Query: 70 RAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRL 129
R EVD + G ++IV+ ID + + V ME GG L + +
Sbjct: 58 RREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVV---MECMEGGELFQRIQDKADGAF 114
Query: 130 QEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSK---NHEFKLCDFGSVSGVIR 186
E E IM ++ V +H+ + HRD+K EN+L + N KL DFG
Sbjct: 115 TEREAAQIMHEICAAVDYLHSRD--IAHRDLKPENLLYTTTQPNATLKLTDFGFAKET-- 170
Query: 187 APRNTEEFNYVQYDIMKNT-TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP 245
+ Y + T Y PE++ + D+ DIW+LGV +Y P
Sbjct: 171 ---------FTSYTLQTPCYTPYYVAPEVLGPEK---YDKSCDIWSLGVVMYIIMCGFPP 218
Query: 246 FEKNG--------ESAILASKFEF--PAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEE 295
F N ++ I +++F P + S K+LI ML VDP KR I V+
Sbjct: 219 FYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISN 278
Query: 296 --VSRIQGIP 303
+++ +P
Sbjct: 279 KWIAQYNAVP 288
>7297240_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 326
Score = 67.4 bits (163), Expect = 8e-11
Identities = 55/207 (26%), Positives = 94/207 (44%), Gaps = 28/207 (13%)
Query: 101 GMYEVYLLMEYCSGGGLIDFMNT--RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHR 158
G E++ +MEYC+GG +D +N +L R++E I I+ + + AA+ + ++HR
Sbjct: 87 GPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYIIRETCR--AAIELNRNHVLHR 144
Query: 159 DIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQ----YRCPEM 214
DI+ +N+LL+KN KLCDFG V + K T + PE+
Sbjct: 145 DIRGDNILLTKNGRVKLCDFGLS-------------RQVDSTLGKRGTCIGSPCWMAPEV 191
Query: 215 IDLY--RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKFEFP-----AYPRY 267
+ R I ++D+WALG+ + PF + + P +
Sbjct: 192 VSAMESREPDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNW 251
Query: 268 SDRVKNLISVMLRVDPLKRPNICQVVE 294
S ++ + IS L + RP + ++VE
Sbjct: 252 SQQINDFISESLEKNAENRPMMVEMVE 278
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 67.0 bits (162), Expect = 1e-10
Identities = 69/258 (26%), Positives = 117/258 (44%), Gaps = 40/258 (15%)
Query: 47 VCPDNVACLKRVVVPDKASLN--------TLRAEVDSMKALRGNKFIVSYIDSHATKSPV 98
V + +K+V VP +S N LR+EV ++K L + IV Y+ +
Sbjct: 1195 VTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDL-DHLNIVQYLGFENKNN-- 1251
Query: 99 NVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHR 158
+Y ++L EY +GG + + R+ R E I ++ +QV +G+A +H+ ++HR
Sbjct: 1252 ---IYSLFL--EYVAGGSVGSLI--RMYGRFDEPLIKHLTTQVLKGLAYLHS--KGILHR 1302
Query: 159 DIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLY 218
D+K +N+LL ++ K+ DFG R +++ Y D+ T + PEM+D
Sbjct: 1303 DMKADNLLLDQDGICKISDFG-------ISRKSKDI-YSNSDMTMRGTVFWMAPEMVDTK 1354
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFE---------KNGESAILASKFEFPAYPRYSD 269
+G K DIW+LG + + P+ K G+S A P S
Sbjct: 1355 QG--YSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSK-SAPPIPEDTLPLISQ 1411
Query: 270 RVKNLISVMLRVDPLKRP 287
+N + ++P KRP
Sbjct: 1412 IGRNFLDACFEINPEKRP 1429
>YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 897
Score = 67.0 bits (162), Expect = 1e-10
Identities = 71/301 (23%), Positives = 127/301 (41%), Gaps = 55/301 (18%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
K + G FA VY ++ D + + R + +K L L E+ +K ++ + I
Sbjct: 28 KEIGKGSFATVYRGHLTS-DKSQHVAIKEVSRAKLKNKKLLENLEIEIAILKKIK-HPHI 85
Query: 86 VSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILN--------- 136
V ID T + + YL+MEYC+ G L F+ R + ++ +L
Sbjct: 86 VGLIDCERTST-------DFYLIMEYCALGDLT-FLLKRRKELMENHPLLRTVFEKYPPP 137
Query: 137 -----------IMSQVSQGVAAMHALQPP-LIHRDIKIENVLLSKN----HEFKLCDFGS 180
++S + Q +A+ L+ L+HRDIK +N+LLS H+ K
Sbjct: 138 SENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTPLIGYHDSKSFHELG 197
Query: 181 VSGVIRAP-RNTEEFNYVQYDIMKNTTAQ--------YRCPEMIDLYRGLPIDEKSDIWA 231
G+ P +F + ++ + NT+ Y PE+++ + + K+D+W+
Sbjct: 198 FVGIYNLPILKIADFGFARF--LPNTSLAETLCGSPLYMAPEILNYQK---YNAKADLWS 252
Query: 232 LGVFLYKTCYYTTPFEKNGESAILA------SKFEFPAYPRYSDRVKNLISVMLRVDPLK 285
+G +++ C T PF + + FP+Y +K LI +L DP +
Sbjct: 253 VGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQ 312
Query: 286 R 286
R
Sbjct: 313 R 313
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 67.0 bits (162), Expect = 1e-10
Identities = 70/302 (23%), Positives = 131/302 (43%), Gaps = 48/302 (15%)
Query: 16 PVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDS 75
P+ ++ + + SG A V + P + VA + + + S++ L E+ +
Sbjct: 59 PICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQA 114
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNR------- 128
M + +V+Y S K E++L+M+ SGG ++D + + NR
Sbjct: 115 MSQC-SHPNVVTYYTSFVVKD-------ELWLVMKLLSGGSMLDIIKY-IVNRGEHKNGV 165
Query: 129 LQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIR-- 186
L+E I I+ +V +G+ +H + IHRD+K N+LL ++ ++ DFG VS +
Sbjct: 166 LEEAIIATILKEVLEGLDYLH--RNGQIHRDLKAGNILLGEDGSVQIADFG-VSAFLATG 222
Query: 187 --APRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTT 244
RN +V T + PE+++ RG D K+D+W+ G+ +
Sbjct: 223 GDVTRNKVRKTFV-------GTPCWMAPEVMEQVRG--YDFKADMWSFGITAIELATGAA 273
Query: 245 PFEK------------NGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
P+ K N + + +Y + L+S+ L+ DP KRP ++
Sbjct: 274 PYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAEL 333
Query: 293 VE 294
++
Sbjct: 334 LK 335
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 67.0 bits (162), Expect = 1e-10
Identities = 62/263 (23%), Positives = 110/263 (41%), Gaps = 27/263 (10%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
K L G F V E+ + LK+ VV + E + N F+
Sbjct: 353 KVLGKGSFGKVLLGELKGRGEYSA--IKALKKDVVLIDDDVECTMVEKRVLTLAAENPFL 410
Query: 86 VSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGV 145
I + TK ++ +ME+ +GG L+ + + R + + +++ G+
Sbjct: 411 THLICTFQTKD-------HLFFVMEFLNGGDLMYHIQDK--GRFELYRATFYAAEIMCGL 461
Query: 146 AAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
+H+ +I+RD+K++NVLL ++ K+ DFG I F
Sbjct: 462 QFLHS--KGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTF---------CG 510
Query: 206 TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS-KFEFPAY 264
T Y PE++ +GL D W+ GV LY+ +PF + E + S + + P Y
Sbjct: 511 TPDYIAPEIL---QGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHY 567
Query: 265 PRY-SDRVKNLISVMLRVDPLKR 286
PR+ + K+++ + +P KR
Sbjct: 568 PRWITKESKDILEKLFEREPTKR 590
>Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 382
Score = 67.0 bits (162), Expect = 1e-10
Identities = 65/263 (24%), Positives = 104/263 (38%), Gaps = 32/263 (12%)
Query: 70 RAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRL 129
R EVD G IV +D + ++ G + ++ME GG L + R
Sbjct: 82 RQEVDHHWQASGGPHIVCILDVYEN---MHHGKRCLLIIMECMEGGELFSRIQERGDQAF 138
Query: 130 QEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS---KNHEFKLCDFGSVSGVIR 186
E E IM + + +H+ + HRD+K EN+L + K+ KL DFG +
Sbjct: 139 TEREAAEIMRDIGTAIQFLHSHN--IAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQ 196
Query: 187 APRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF 246
T + T Y PE++ + D+ D+W+LGV +Y PF
Sbjct: 197 NALQTPCY-----------TPYYVAPEVLGPEK---YDKSCDMWSLGVIMYILLCGFPPF 242
Query: 247 EKNGESAILASK----------FEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEV 296
N AI F P + S+ K LI ++L+ DP +R I Q +
Sbjct: 243 YSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHP 302
Query: 297 SRIQGIPCPIKNFYLLRMMDKQE 319
Q + P + R++ + +
Sbjct: 303 WINQSMVVPQTPLHTARVLQEDK 325
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 67.0 bits (162), Expect = 1e-10
Identities = 71/263 (26%), Positives = 121/263 (45%), Gaps = 32/263 (12%)
Query: 23 KVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRG- 81
++LK + G F V V++ D V + L + + +A R E D + + G
Sbjct: 78 EILKVIGRGAFGEVAVVKLKNADKVFAMKI--LNKWEMLKRAETACFREERDVL--VNGD 133
Query: 82 NKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQV 141
NK+I + +A + N+ YL+M+Y GG L+ ++ + ++RL E ++++
Sbjct: 134 NKWITTL--HYAFQDDNNL-----YLVMDYYVGGDLLTLLS-KFEDRLPEDMARFYLAEM 185
Query: 142 SQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDI 201
+ ++H L +HRDIK +N+L+ N +L DFGS ++ E VQ +
Sbjct: 186 VIAIDSVHQLH--YVHRDIKPDNILMDMNGHIRLADFGSCLKLM-------EDGTVQSSV 236
Query: 202 MKNTTAQYRCPEMIDLYRGLP--IDEKSDIWALGVFLYKTCYYTTPF------EKNGESA 253
T Y PE++ + D W+LGV +Y+ Y TPF E G+
Sbjct: 237 AVG-TPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIM 295
Query: 254 ILASKFEFPA-YPRYSDRVKNLI 275
+F+FPA S+ K+LI
Sbjct: 296 NHKERFQFPAQVTDVSENAKDLI 318
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 67.0 bits (162), Expect = 1e-10
Identities = 64/211 (30%), Positives = 96/211 (45%), Gaps = 34/211 (16%)
Query: 107 LLMEYCSGGGLIDFMNTRLQN--RLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
++MEY +GG L + R+ N R E E Q+ GV+ HA+Q + HRD+K+EN
Sbjct: 94 IVMEYAAGGELYE----RICNAGRFSEDEARFFFQQLISGVSYCHAMQ--ICHRDLKLEN 147
Query: 165 VLL--SKNHEFKLCDFG-SVSGVIRA-PRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRG 220
LL S K+CDFG S S V+ + P++T T Y PE+ L R
Sbjct: 148 TLLDGSPAPRLKICDFGYSKSSVLHSQPKSTV------------GTPAYIAPEI--LLRQ 193
Query: 221 LPIDEKSDIWALGVFLYKTCYYTTPFEKNGE--------SAILASKFEFPAYPRYSDRVK 272
+ +D+W+ GV LY PFE E IL+ + P S +
Sbjct: 194 EYDGKLADVWSCGVTLYVMLVGAYPFEDPQEPRDYRKTIQRILSVTYSIPEDLHLSPECR 253
Query: 273 NLISVMLRVDPLKRPNICQVVEEVSRIQGIP 303
+LIS + DP R I ++ + ++ +P
Sbjct: 254 HLISRIFVADPATRITIPEITSDKWFLKNLP 284
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 67.0 bits (162), Expect = 1e-10
Identities = 80/367 (21%), Positives = 155/367 (41%), Gaps = 47/367 (12%)
Query: 21 QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALR 80
+ ++++ + SG + VY + + + +A +K + + + ++ E+ M+ R
Sbjct: 25 EYELIQKIGSGTYGDVYKAK-----RIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCR 79
Query: 81 GNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQ 140
+ I++Y S+ + ++++ ME+C GG L D ++ L E +I + +
Sbjct: 80 -HPNIIAYYGSYLRRD-------KLWICMEFCGGGSLQDIY--QVTGPLTEVQIAYMCRE 129
Query: 141 VSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYD 200
+G+ +H++ +HRDIK N+LL++ + KL DFG VS I A N + +++
Sbjct: 130 TLKGLEYLHSMGK--MHRDIKGANILLTEYGDVKLADFG-VSAQITATINKRK-SFI--- 182
Query: 201 IMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTP-FEKNGESAI-LASK 258
T + PE+ + R ++ DIWA G+ + P F+ + A+ L SK
Sbjct: 183 ----GTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSK 238
Query: 259 FEFPA-----YPRYSDRVKNLISVMLRVDPLKRPNI----------CQVVEEVSR--IQG 301
F ++S N I L +P KRP C++ V++ +Q
Sbjct: 239 SGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQK 298
Query: 302 IPCPIKNFYLLRMMDKQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQVVSNVQTPSKT 361
P FY +D E+ P + L + +N ++
Sbjct: 299 YQSPNPQFYY--YLDGDEESVAGVPQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERS 356
Query: 362 ASIQHLP 368
+S + LP
Sbjct: 357 SSPETLP 363
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 67.0 bits (162), Expect = 1e-10
Identities = 63/239 (26%), Positives = 106/239 (43%), Gaps = 38/239 (15%)
Query: 62 DKASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFM 121
D+ +L + EV+ MK L+ + I+ TK+ + Y++ EY S G + D++
Sbjct: 178 DQTNLQKVYREVEIMKRLK-HPHIIKLYQVMETKNMI-------YIVSEYASQGEIFDYI 229
Query: 122 NT--RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG 179
R+ F+ I+S V + + ++HRD+K EN+LL N K+ DFG
Sbjct: 230 AKYGRMSESAARFKFWQIISAVE------YCHKKGIVHRDLKAENLLLDLNMNIKIADFG 283
Query: 180 SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMID--LYRGLPIDEKSDIWALGVFLY 237
+ F + + Y PE+ + Y G I DIW+LGV LY
Sbjct: 284 F----------SNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEI----DIWSLGVVLY 329
Query: 238 KTCYYTTPFE----KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
PF+ ++ +L+ +F P + S ++LI ML ++P +R I Q+
Sbjct: 330 VLVCGALPFDGSTLQSLRDRVLSGRFRIPFF--MSSECEHLIRRMLVLEPTRRYTIDQI 386
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 66.6 bits (161), Expect = 1e-10
Identities = 45/148 (30%), Positives = 76/148 (50%), Gaps = 14/148 (9%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
V+L+MEYC+GG L D++ + L E I + Q++ + +H+ +IHRD+K +N
Sbjct: 81 VFLVMEYCNGGDLADYLQAK--GTLSEDTIRVFLHQIAAAMRILHS--KGIIHRDLKPQN 136
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGL 221
+LLS + K SVSG+ + Y+ ++M T + Y PE+I
Sbjct: 137 ILLSYANRRK----SSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVI---MSQ 189
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFEKN 249
D K+D+W++G +Y+ PF+ N
Sbjct: 190 HYDAKADLWSIGTVIYQCLVGKPPFQAN 217
>Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1191
Score = 66.6 bits (161), Expect = 1e-10
Identities = 45/128 (35%), Positives = 66/128 (51%), Gaps = 13/128 (10%)
Query: 109 MEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLS 168
ME+C G + D + N L+E I I ++ +G+A +HA + +IHRDIK +NVLL+
Sbjct: 1 MEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHK--VIHRDIKGQNVLLT 58
Query: 169 KNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEK 226
+N E KL DFG + + R F Y + PE+I D D +
Sbjct: 59 ENAEVKLVDFGVSAQLDRTVGRRNTFIGTPY---------WMAPEVIACDENPDATYDYR 109
Query: 227 SDIWALGV 234
SDIW+LG+
Sbjct: 110 SDIWSLGI 117
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 66.6 bits (161), Expect = 1e-10
Identities = 62/263 (23%), Positives = 110/263 (41%), Gaps = 27/263 (10%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
K L G F V E+ + LK+ VV + E + N F+
Sbjct: 353 KVLGKGSFGKVLLGELKGRGEYFA--IKALKKDVVLIDDDVECTMVEKRVLTLAAENPFL 410
Query: 86 VSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGV 145
I + TK ++ +ME+ +GG L+ + + R + + +++ G+
Sbjct: 411 THLICTFQTKD-------HLFFVMEFLNGGDLMYHIQDK--GRFELYRATFYAAEIMCGL 461
Query: 146 AAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
+H+ +I+RD+K++NVLL ++ K+ DFG I F
Sbjct: 462 QFLHS--KGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTF---------CG 510
Query: 206 TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS-KFEFPAY 264
T Y PE++ +GL D W+ GV LY+ +PF + E + S + + P Y
Sbjct: 511 TPDYIAPEIL---QGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHY 567
Query: 265 PRY-SDRVKNLISVMLRVDPLKR 286
PR+ + K+++ + +P KR
Sbjct: 568 PRWITKESKDILEKLFEREPTKR 590
>ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 586
Score = 66.6 bits (161), Expect = 1e-10
Identities = 75/277 (27%), Positives = 119/277 (42%), Gaps = 33/277 (11%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRV-VVPDKASLNTLRAEVDS 75
+ ++++LK + GG + VY V NV LKRV ++ D+ L++ E++
Sbjct: 284 IKGREIEILKQIGKGGSSKVYKVLFG-------SNVYALKRVELIGDEKMLSSYINEINL 336
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEIL 135
+ +G IV ID VG +++L+EY G D + L I
Sbjct: 337 LYKFKGTSEIVEIIDHE-------VGEDYLHILLEY----GETDLSKIIRKGGLSMNFIK 385
Query: 136 NIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFN 195
++ Q+ V +H + +IH D+K N L K KL DFG +S VIR T +
Sbjct: 386 DVWEQMLLIVKRVHIER--IIHCDLKPANFLFVKGR-VKLIDFG-ISKVIRND-TTSILS 440
Query: 196 YVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL 255
Q T Y PE + + + SDIW+LG LY+ + P +
Sbjct: 441 EEQCG-----TVNYMSPEAVTQNKS-KVARSSDIWSLGCILYEMVHSNPPLHEYPNLIQK 494
Query: 256 ASKFEFPAYPRYSDRVKNLISVM---LRVDPLKRPNI 289
+ + + +Y+ + K + VM L DP KRP I
Sbjct: 495 IQRLQEYSEFKYTSKNKAAVMVMKECLARDPKKRPTI 531
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 66.6 bits (161), Expect = 1e-10
Identities = 64/241 (26%), Positives = 99/241 (40%), Gaps = 34/241 (14%)
Query: 64 ASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
A ++ EV+ MK L + Y + V Y Y+++EY GG +
Sbjct: 213 AKTRDIQNEVEVMKKLSHPNIVAIY-------DCITVAKYS-YMVIEYVGGGEFFSKLVD 264
Query: 124 RLQNRLQEFEILN--IMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHE---FKLCDF 178
N++ E L Q+ V +H++ + HRDIK EN+L S E KL DF
Sbjct: 265 SKYNQMGLGESLGKYFAFQLIDAVLYLHSVG--ICHRDIKPENILCSNKAERCILKLTDF 322
Query: 179 GSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYK 238
G + + T Y PE++ +G+ K DIW+LG L+
Sbjct: 323 GMAKNSVNRMKT------------HCGTPSYCAPEIV-ANQGVEYTPKVDIWSLGCVLFI 369
Query: 239 TCYYTTPFE------KNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQV 292
T PF K E + F + R +D +N+I ML V+PL RP+ ++
Sbjct: 370 TFSGYPPFSEEYTDLKMDEQVLTGRLFFHEQWHRITDETQNMIQWMLTVEPLIRPSAVEL 429
Query: 293 V 293
+
Sbjct: 430 M 430
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 66.6 bits (161), Expect = 1e-10
Identities = 60/253 (23%), Positives = 111/253 (43%), Gaps = 36/253 (14%)
Query: 63 KASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMN 122
+ S++ L E+ +M + +VSY S + E++++M + G ++D +
Sbjct: 94 QTSVDELSHEIQAMSQCN-HPNVVSYYTSF-------IAQEELWVVMRLLNCGSMLDILK 145
Query: 123 TRLQ---------NRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEF 173
+++ L E I ++ +V +G+ H IHRDIK N+LL+ +
Sbjct: 146 RKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQ--IHRDIKAGNILLADDGTI 203
Query: 174 KLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALG 233
++ DFG VSG + + V++ + T + PE+++ +G D K+DIW+LG
Sbjct: 204 QIADFG-VSGWLASSGGDLSRQKVRHTFV--GTPCWMAPEVMEQVQG--YDFKADIWSLG 258
Query: 234 VFLYKTCYYTTPFEK------------NGESAILASKFEFPAYPRYSDRVKNLISVMLRV 281
+ + T P+ K N + + Y Y K LI L+
Sbjct: 259 ILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQK 318
Query: 282 DPLKRPNICQVVE 294
DP KRP ++++
Sbjct: 319 DPAKRPTASELLK 331
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 66.6 bits (161), Expect = 1e-10
Identities = 47/191 (24%), Positives = 90/191 (46%), Gaps = 30/191 (15%)
Query: 105 VYLLMEYCSGGGLIDFMNT-RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
+Y++MEY GG L++ M + + + F +++ + +AA+H++ IHRD+K +
Sbjct: 141 LYMVMEYMPGGDLVNLMTSYEVSEKWTRF----YTAEIVEALAALHSMG--YIHRDVKPD 194
Query: 164 NVLLSKNHEFKLCDFG-----SVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLY 218
N+L+S + KL DFG + +GV+R +Y+ ++++N
Sbjct: 195 NMLISISGHIKLADFGTCVKMNANGVVRCSTAVGTPDYISPEVLRNQG------------ 242
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILA------SKFEFPAYPRYSDRVK 272
+ ++ D W++GVF+Y+ TPF + + +FP P S + K
Sbjct: 243 QDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPLISTQAK 302
Query: 273 NLISVMLRVDP 283
++I L P
Sbjct: 303 DIIKKFLSAAP 313
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 66.6 bits (161), Expect = 1e-10
Identities = 73/273 (26%), Positives = 113/273 (40%), Gaps = 33/273 (12%)
Query: 26 KYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNKFI 85
K L G F HVY + V V L + + + LR EV+ LR +
Sbjct: 35 KPLGRGKFGHVYLAREKRSNHVVALKV--LFKSQLQQSQVEHQLRREVEIQSHLRHPNIL 92
Query: 86 VSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGV 145
Y + K VYL++EY + G L + + + E ++ +++ +
Sbjct: 93 RLYGYFYDQK--------RVYLILEYAARGEL--YKDLQKCKYFSERRAATYVASLARAL 142
Query: 146 AAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT 205
H +IHRDIK EN+L+ E K+ DFG + FN +
Sbjct: 143 IYCHGKH--VIHRDIKPENLLIGAQGELKIADFG---------WSVHTFNRRR---TMCG 188
Query: 206 TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEF 261
T Y PEM++ + D DIW+LG+ Y+ Y PFE S I+ +F
Sbjct: 189 TLDYLPPEMVE---SVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKF 245
Query: 262 PAYPRYSDRVKNLISVMLRVDPLKRPNICQVVE 294
P P S K+LIS ML + +R + +++E
Sbjct: 246 PPKPIISASAKDLISQMLVKESSQRLPLHKLLE 278
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 66.6 bits (161), Expect = 1e-10
Identities = 76/295 (25%), Positives = 122/295 (40%), Gaps = 30/295 (10%)
Query: 4 PQIEKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDK 63
P+ A T+ P GS K + L G F HVY S +C L +
Sbjct: 384 PRSPARAEATVSP-GSRWKKG-RLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSR 441
Query: 64 ASLNTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNT 123
S L E+ + LR ++ IV Y S ++Y+ +EY SGG + +
Sbjct: 442 ESAQQLGQEISVLSRLR-HQNIVQYYGSETVDD-------KLYIYLEYVSGGSIYKLLQE 493
Query: 124 RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSG 183
+ E I N Q+ G+A +HA +HRDIK N+L+ + K+ DFG ++
Sbjct: 494 --YGQFGENAIRNYTQQILSGLAYLHAKNT--VHRDIKGANILVDPHGRVKVADFG-MAK 548
Query: 184 VIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYT 243
I A F Y + PE+I G + DIW+LG + +
Sbjct: 549 HITAQSGPLSFKGSPY---------WMAPEVIKNSNGSNL--AVDIWSLGCTVLEMATTK 597
Query: 244 TPFEK-NGESAI--LASKFEFPAYPRY-SDRVKNLISVMLRVDPLKRPNICQVVE 294
P+ + G A+ + + E P P + S+ K+ + L+ +P RP Q+++
Sbjct: 598 PPWSQYEGVPAMFKIGNSKELPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLD 652
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 66.6 bits (161), Expect = 1e-10
Identities = 78/286 (27%), Positives = 119/286 (41%), Gaps = 34/286 (11%)
Query: 16 PVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKAS---LNTLRAE 72
P G K K+L SG F VY S +C +V+ D+ S L L E
Sbjct: 208 PSGFSTWKKGKFLGSGTFGQVYLGFNSEKGKMCAIKEV---KVISDDQTSKECLKQLNQE 264
Query: 73 VDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEF 132
++ + L + IV Y S ++ ++V +EY SGG + + E
Sbjct: 265 INLLNQLC-HPNIVQYYGSELSEETLSV-------YLEYVSGGSIHKLLKD--YGSFTEP 314
Query: 133 EILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTE 192
I N Q+ G+A +H +HRDIK N+L+ N E KL DFG V A
Sbjct: 315 VIQNYTRQILAGLAYLHGRNT--VHRDIKGANILVDPNGEIKLADFGMAKHV-TAFSTML 371
Query: 193 EFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEK-NGE 251
F Y + PE++ G DIW+LG + + P+ + G
Sbjct: 372 SFKGSPY---------WMAPEVVMSQNG--YTHAVDIWSLGCTILEMATSKPPWSQFEGV 420
Query: 252 SAI--LASKFEFPAYPRY-SDRVKNLISVMLRVDPLKRPNICQVVE 294
+AI + + + P P + S+ KN I + L+ +P RP Q++E
Sbjct: 421 AAIFKIGNSKDTPEIPDHLSNDAKNFIRLCLQRNPTVRPTASQLLE 466
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 66.6 bits (161), Expect = 1e-10
Identities = 60/199 (30%), Positives = 99/199 (49%), Gaps = 26/199 (13%)
Query: 104 EVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIE 163
++YL+MEYC GG L + ++ + R+ F+ Q+ G+ +H+ + +IH+DIK
Sbjct: 220 KMYLVMEYCVGG-LQEMIDYQPDKRMPLFQAHGYFKQLVDGLEYLHSCR--VIHKDIKPG 276
Query: 164 NVLLSKNHEFKLCDFGSVSGV-IRAPRNTEEFNYVQYDIMKNTTAQ----YRCPEMIDLY 218
N+LLS + K+ DFG + + AP +T TT Q ++ PE+ + +
Sbjct: 277 NLLLSLDQTLKISDFGVAEQLDLFAPDDT------------CTTGQGSPAFQPPEIANGH 324
Query: 219 RGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS----KFEFPAYPRYSDR-VKN 273
K DIW+ GV LY PFE + +L + ++E PA+ D N
Sbjct: 325 ETF-AGFKVDIWSSGVTLYNLATGQYPFEGDNIYRLLENIGRGQWEAPAWLYEMDADFAN 383
Query: 274 LISVMLRVDPLKRPNICQV 292
LI ML+ DP KR ++ ++
Sbjct: 384 LILGMLQADPSKRLSLQEI 402
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 66.2 bits (160), Expect = 2e-10
Identities = 55/177 (31%), Positives = 77/177 (43%), Gaps = 22/177 (12%)
Query: 116 GLIDFMNT-RLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFK 174
G ID + + + EFE I QV G+ +H ++HRDIK ENV++ K
Sbjct: 1188 GCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLH--DQGIVHRDIKDENVIVDSKGFVK 1245
Query: 175 LCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMI--DLYRGLPIDEKSDIWAL 232
+ DFGS + V P +D+ T Y PE++ + Y G P DIWA+
Sbjct: 1246 IIDFGSAAYVKSGP----------FDVFVG-TIDYAAPEVLGGNPYEGQP----QDIWAI 1290
Query: 233 GVFLYKTCYYTTPFEKNGESAILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNI 289
G+ LY + PF E IL +F S+ LI +L KRP I
Sbjct: 1291 GILLYTVVFKENPFYNIDE--ILEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTI 1345
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 66.2 bits (160), Expect = 2e-10
Identities = 66/285 (23%), Positives = 126/285 (44%), Gaps = 41/285 (14%)
Query: 16 PVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDS 75
P+G +++K + + G V +V S +V +KR+ + L E+
Sbjct: 104 PLGKYEMKKQIGVGASGTVFVANVAGST-------DVVAVKRMAFKTQPKKEMLLTEIKV 156
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEIL 135
MK R + +V+YI+S+ + +++++M+Y GG L D + ++ L E +I
Sbjct: 157 MKQYR-HPNLVNYIESYLVDAD------DLWVVMDYLEGGNLTDVV---VKTELDEGQIA 206
Query: 136 NIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFN 195
++ + + + +H + ++HRDIK +NVLL N E KL D G + + +
Sbjct: 207 AVLQECLKALHFLH--RHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVG 264
Query: 196 YVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAIL 255
T + PE+++ + + K DIW+LG+ + P+ + E+ +
Sbjct: 265 ----------TPYWMSPEILNKKQ---YNYKVDIWSLGIMALEMIDGEPPYLR--ETPLK 309
Query: 256 A-------SKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
A K E R S N + L VDP +R + +++
Sbjct: 310 AIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELL 354
>CE04904 [T] KOG0194 Protein tyrosine kinase
Length = 433
Score = 66.2 bits (160), Expect = 2e-10
Identities = 73/305 (23%), Positives = 130/305 (41%), Gaps = 35/305 (11%)
Query: 21 QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPD--KASLNTLRAEVDSMKA 78
Q+ + K L G F V S + + VA +K+V + KA + AE +M+
Sbjct: 129 QITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVA-IKQVKLDKTGKAKIKDFLAEARTMRK 187
Query: 79 LRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIM 138
L G++ I+ + + P+ YL+ME G L F+ + L + ++
Sbjct: 188 L-GHQNIIKFYGVGVLQEPL-------YLVMELAVNGALDSFL--KKNEDLSVDKKTEMI 237
Query: 139 SQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQ 198
Q + G+ +H P++HRDI N L + + K+ DFG N
Sbjct: 238 LQAAWGLEYIHG--KPMLHRDIAARNCLYTDG-KVKISDFGLTR------------NGTV 282
Query: 199 YDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVF---LYKTCYYTTPFEKNGESAI- 254
Y I NT + R I+ + + EK+D+WA GV ++ P K + A
Sbjct: 283 YQIKPNTKSPIRWLA-IETIKTMICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQ 341
Query: 255 LASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRM 314
+A+ + P YP ++ +++ +P RP++ ++ E + R+ P P NF +
Sbjct: 342 VANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEILQRVTETPRP--NFTAIAK 399
Query: 315 MDKQE 319
+ +E
Sbjct: 400 KEAEE 404
>At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 411
Score = 66.2 bits (160), Expect = 2e-10
Identities = 50/199 (25%), Positives = 95/199 (47%), Gaps = 22/199 (11%)
Query: 107 LLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVL 166
+++EYC GG L F+ + +L ++ + +++G++ +H+ + ++HRD+K EN+L
Sbjct: 203 VVVEYCPGGALKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQK--IVHRDVKTENML 260
Query: 167 LSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEK 226
L K+ K+ DFG P + + T Y PE+++ G P + K
Sbjct: 261 LDKSRTLKIADFGVARLEASNPNDMTG---------ETGTLGYMAPEVLN---GSPYNRK 308
Query: 227 SDIWALGVFLYKTCYYTTPFEKNGESAILASKFE---FPAYPRYSDRVKNLISVMLR--- 280
D+++ G+ L++ P+ S + ++ P PR +L +VM R
Sbjct: 309 CDVYSFGICLWEIYCCDMPYPDLSFSEVTSAVVRQNLRPEIPRCCP--SSLANVMKRCWD 366
Query: 281 VDPLKRPNICQVVEEVSRI 299
+P KRP + +VV + I
Sbjct: 367 ANPEKRPEMEEVVAMLEAI 385
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/195 (29%), Positives = 88/195 (44%), Gaps = 30/195 (15%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
+YL++EY G L + + E IM +++ + H + +IHRDIK EN
Sbjct: 150 IYLILEYAPRGEL--YKELQKSCTFDEQRTATIMEELADALMYCHGKK--VIHRDIKPEN 205
Query: 165 VLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNT---TAQYRCPEMIDLYRGL 221
+LL E K+ DFG + AP + + T T Y PEMI+ G
Sbjct: 206 LLLGLKGELKIADFG---WSVHAP-----------SLRRKTMCGTLDYLPPEMIE---GR 248
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFEKNGES----AILASKFEFPAYPRYSDRVKNLISV 277
+EK D+W +GV Y+ PFE + I+ +FPA ++LIS
Sbjct: 249 MHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPA--SVPTGAQDLISK 306
Query: 278 MLRVDPLKRPNICQV 292
+LR +P +R + QV
Sbjct: 307 LLRHNPSERLPLAQV 321
>Hs4503787 [T] KOG0197 Tyrosine kinases
Length = 505
Score = 65.9 bits (159), Expect = 2e-10
Identities = 67/275 (24%), Positives = 121/275 (43%), Gaps = 29/275 (10%)
Query: 17 VGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSM 76
+ + +++LK L SG F V+ + PV V LK P N E M
Sbjct: 229 IDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVA---VKTLK----PGSMDPNDFLREAQIM 281
Query: 77 KALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILN 136
K LR K I Y + P+ Y++ E G L +++ +++ + ++
Sbjct: 282 KNLRHPKLIQLYAVC-TLEDPI-------YIITELMRHGSLQEYLQNDTGSKIHLTQQVD 333
Query: 137 IMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNY 196
+ +QV+ G+A + + IHRD+ NVL+ +++ +K+ DFG ++ V + + E+
Sbjct: 334 MAAQVASGMAYLESRN--YIHRDLAARNVLVGEHNIYKVADFG-LARVFKV--DNEDIYE 388
Query: 197 VQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYY-TTPFE-KNGESAI 254
+++I ++ PE I R KSD+W+ G+ LY+ Y P+ G I
Sbjct: 389 SRHEI--KLPVKWTAPEAI---RSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVI 443
Query: 255 --LASKFEFPAYPRYSDRVKNLISVMLRVDPLKRP 287
LA + P + N++ +P +RP
Sbjct: 444 QMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERP 478
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 65.9 bits (159), Expect = 2e-10
Identities = 84/361 (23%), Positives = 143/361 (39%), Gaps = 44/361 (12%)
Query: 24 VLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNK 83
+LK L G F V VE+ + + CLK+ V+ + E +
Sbjct: 240 LLKVLGKGSFGKVMLVELKGKNEFYA--MKCLKKDVILEDDDTECTYIERRVLILASQCP 297
Query: 84 FIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQ 143
F+ S T ++ +MEY +GG L+ + ++++F+ +
Sbjct: 298 FLCQLFCSFQTNE-------YLFFVMEYLNGGDLMHHIQ-----QIKKFDEARTRFYACE 345
Query: 144 GVAAMHALQPP-LIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
V A+ L +I+RD+K++NVLL + KL DF G+ + N E + M
Sbjct: 346 IVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADF----GMAKTEMNRE-------NGM 394
Query: 203 KNT---TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKF 259
+T T Y PE+I +G +E D W+ GV +Y+ +PF GE + S
Sbjct: 395 ASTFCGTPDYISPEII---KGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSIL 451
Query: 260 -EFPAYPR-YSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMD- 316
E P +P+ S +S + +P R + + + PI+ R +D
Sbjct: 452 NERPYFPKTISKEAAKCLSALFDRNPNTRLGMPECPDG---------PIRQHCFFRGVDW 502
Query: 317 KQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQVVSNVQTPSKTASIQHLPYLHVSKSQ 376
K+ + R PPP P + ++ V + ASI +L+ S +
Sbjct: 503 KRFENRQVPPPFKPNIKSNSDASNFDDDFTNEKAALTPVHDKNLLASIDPEAFLNFSYTN 562
Query: 377 P 377
P
Sbjct: 563 P 563
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 65.9 bits (159), Expect = 2e-10
Identities = 84/361 (23%), Positives = 143/361 (39%), Gaps = 44/361 (12%)
Query: 24 VLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDSMKALRGNK 83
+LK L G F V VE+ + + CLK+ V+ + E +
Sbjct: 377 LLKVLGKGSFGKVMLVELKGKNEFYA--MKCLKKDVILEDDDTECTYIERRVLILASQCP 434
Query: 84 FIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQ 143
F+ S T ++ +MEY +GG L+ + ++++F+ +
Sbjct: 435 FLCQLFCSFQTNE-------YLFFVMEYLNGGDLMHHIQ-----QIKKFDEARTRFYACE 482
Query: 144 GVAAMHALQPP-LIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFNYVQYDIM 202
V A+ L +I+RD+K++NVLL + KL DF G+ + N E + M
Sbjct: 483 IVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADF----GMAKTEMNRE-------NGM 531
Query: 203 KNT---TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILASKF 259
+T T Y PE+I +G +E D W+ GV +Y+ +PF GE + S
Sbjct: 532 ASTFCGTPDYISPEII---KGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSIL 588
Query: 260 -EFPAYPR-YSDRVKNLISVMLRVDPLKRPNICQVVEEVSRIQGIPCPIKNFYLLRMMD- 316
E P +P+ S +S + +P R + + + PI+ R +D
Sbjct: 589 NERPYFPKTISKEAAKCLSALFDRNPNTRLGMPECPDG---------PIRQHCFFRGVDW 639
Query: 317 KQEQPRVSPPPHVPQMXXXXXXXXXXXXQHLPPQVVSNVQTPSKTASIQHLPYLHVSKSQ 376
K+ + R PPP P + ++ V + ASI +L+ S +
Sbjct: 640 KRFENRQVPPPFKPNIKSNSDASNFDDDFTNEKAALTPVHDKNLLASIDPEAFLNFSYTN 699
Query: 377 P 377
P
Sbjct: 700 P 700
>At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 520
Score = 65.9 bits (159), Expect = 2e-10
Identities = 69/292 (23%), Positives = 128/292 (43%), Gaps = 30/292 (10%)
Query: 7 EKYASGTILPVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASL 66
E +S T SH+++V + SG + V I P+ + LK++ + ++
Sbjct: 68 ESESSETTYQCASHEMRVFGAIGSGA-SSVVQRAIHIPN----HRILALKKINIFEREKR 122
Query: 67 NTLRAEVDSMKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQ 126
L E+ ++ ++ +V D H + G ++ + +EY +GG L D + ++
Sbjct: 123 QQLLTEIRTLCEAPCHEGLV---DFHGAFYSPDSG--QISIALEYMNGGSLADIL--KVT 175
Query: 127 NRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIR 186
++ E + ++ ++ QG++ +H ++ L+HRDIK N+L++ E K+ DFG +G+
Sbjct: 176 KKIPEPVLSSLFHKLLQGLSYLHGVRH-LVHRDIKPANLLINLKGEPKITDFGISAGLEN 234
Query: 187 APRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPF 246
+ F T Y PE I R +DIW+LG+ L++ P+
Sbjct: 235 SMAMCATF---------VGTVTYMSPERI---RNDSYSYPADIWSLGLALFECGTGEFPY 282
Query: 247 EKNGESA-----ILASKFEFPAYPRYSDRVKNLISVMLRVDPLKRPNICQVV 293
N IL P +S + I L+ DP RP Q++
Sbjct: 283 IANEGPVNLMLQILDDPSPTPPKQEFSPEFCSFIDACLQKDPDARPTADQLL 334
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 65.9 bits (159), Expect = 2e-10
Identities = 62/198 (31%), Positives = 88/198 (44%), Gaps = 27/198 (13%)
Query: 105 VYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNIMSQVSQGVAAMHALQPPLIHRDIKIEN 164
V+L+ME C GG L D + R E E ++ + V A H+L ++HRD+K EN
Sbjct: 96 VHLVMELCEGGELFDRIVKR--GHYSEREAAKLIKTIVGVVEACHSLG--VVHRDLKPEN 151
Query: 165 VLLSKNHE---FKLCDFGSVSGVIRAPRNTEEFNYVQYDIMKNTTAQYRCPEMIDLYRGL 221
L S + E K DFG V P E F+ + +A Y PE++ + G
Sbjct: 152 FLFSSSDEDASLKSTDFG--LSVFCTP--GEAFSELV------GSAYYVAPEVLHKHYG- 200
Query: 222 PIDEKSDIWALGVFLYKTCYYTTPFEKNGESAILAS------KFEFPAYPRYSDRVKNLI 275
+ D+W+ GV LY PF E I +FE +P S+ K+LI
Sbjct: 201 ---PECDVWSAGVILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPWPSISESAKDLI 257
Query: 276 SVMLRVDPLKRPNICQVV 293
ML +P KR QV+
Sbjct: 258 KKMLESNPKKRLTAHQVL 275
>At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 561
Score = 65.9 bits (159), Expect = 2e-10
Identities = 65/282 (23%), Positives = 119/282 (42%), Gaps = 35/282 (12%)
Query: 16 PVGSHQVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRAEVDS 75
P+ + K+ + + G A V+ P + V V L++ L+ +R EV +
Sbjct: 10 PLNAKDYKLYEEIGDGVSATVHRALCIPLNVVVAIKVLDLEKC----NNDLDGIRREVQT 65
Query: 76 MKALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEIL 135
M + + ++ S T ++++++M Y +GG + + + + +E I
Sbjct: 66 MSLINHPNVLQAHC-SFTTG-------HQLWVVMPYMAGGSCLHIIKSSYPDGFEEPVIA 117
Query: 136 NIMSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFGSVSGVIRAPRNTEEFN 195
++ + + + +HA IHRD+K N+LL N KL DFG VS + F+
Sbjct: 118 TLLRETLKALVYLHAHGH--IHRDVKAGNILLDSNGAVKLADFG-VSACM--------FD 166
Query: 196 YVQYDIMKNT---TAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTCYYTTPFEKNGES 252
+NT T + PE++ G D K+D+W+ G+ + + PF K
Sbjct: 167 TGDRQRSRNTFVGTPCWMAPEVMQQLHG--YDFKADVWSFGITALELAHGHAPFSKYPPM 224
Query: 253 AILASK-------FEFPAYPRYSDRVKNLISVMLRVDPLKRP 287
+L ++ R+S K ++ L DP KRP
Sbjct: 225 KVLLMTLQNAPPGLDYERDKRFSKAFKEMVGTCLVKDPKKRP 266
>At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 553
Score = 65.9 bits (159), Expect = 2e-10
Identities = 67/294 (22%), Positives = 139/294 (46%), Gaps = 55/294 (18%)
Query: 21 QVKVLKYLASGGFAHVYSVEISPPDPVCPDNVACLKRVVVPDKASLNTLRA---EVDSMK 77
Q+K+ K +A G + ++ C VA +++ P++ + LR EV M+
Sbjct: 274 QLKIEKKVACGSYGELFR------GTYCSQEVAI--KILKPERVNAEMLREFSQEVYIMR 325
Query: 78 ALRGNKFIVSYIDSHATKSPVNVGMYEVYLLMEYCSGGGLIDFMNTRLQNRLQEFEILNI 137
+R +K +V +I + T+SP + ++ E+ + G + DF++ + + +L +
Sbjct: 326 KVR-HKNVVQFIGA-CTRSP------NLCIVTEFMTRGSIYDFLHKH-KGVFKIQSLLKV 376
Query: 138 MSQVSQGVAAMHALQPPLIHRDIKIENVLLSKNHEFKLCDFG-----SVSGVIRAPRNTE 192
VS+G+ +H Q +IHRD+K N+L+ ++ K+ DFG + SGV+ A
Sbjct: 377 ALDVSKGMNYLH--QNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESGVMTA----- 429
Query: 193 EFNYVQYDIMKNTTAQYRCPEMIDLYRGLPIDEKSDIWALGVFLYKTC------YYTTPF 246
+ T ++ PE+I+ P D ++D+++ + L++ Y TP
Sbjct: 430 ----------ETGTYRWMAPEVIE---HKPYDHRADVFSYAIVLWELLTGELPYSYLTPL 476
Query: 247 EKNGESAILASKFEFPAYPRYS-DRVKNLISVMLRVDPLKRPNICQVVEEVSRI 299
+ + + K P P+ + ++ L+ + DP RPN +++E ++++
Sbjct: 477 Q---AAVGVVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQL 527
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,337,810
Number of Sequences: 60738
Number of extensions: 1568726
Number of successful extensions: 7029
Number of sequences better than 1.0e-05: 815
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 799
Number of HSP's that attempted gapping in prelim test: 5798
Number of HSP's gapped (non-prelim): 908
length of query: 777
length of database: 30,389,216
effective HSP length: 114
effective length of query: 663
effective length of database: 23,465,084
effective search space: 15557350692
effective search space used: 15557350692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)