ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactV2232    suspect: LH   DK    KOG4466  Cell cycle control, cell division, chromosome partitioning     Component of histone deacetylase complex (breast carcinoma metastasis suppressor 1 protein in human)
r_klactV2232    suspect: LH   DK    KOG4466  Transcription                                                  Component of histone deacetylase complex (breast carcinoma metastasis suppressor 1 protein in human)

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactV2232 776044 775088 -319 
         (319 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YIL084c [DK] KOG4466 Component of histone deacetylase complex (b...   218   1e-56

>YIL084c [DK] KOG4466 Component of histone deacetylase complex (breast
           carcinoma metastasis suppressor 1 protein in human)
          Length = 327

 Score =  218 bits (554), Expect = 1e-56
 Identities = 133/320 (41%), Positives = 171/320 (52%), Gaps = 37/320 (11%)

Query: 32  QDLSRKDKKRLQFEGKVGKIRTSFAKDKDVHYRDRXXXXXXXXXXXHQGNNPXXXXXXXX 91
           +DLSRKDK+R   E KV KI  +F  ++D  Y+DR           HQG+N         
Sbjct: 9   KDLSRKDKRRFNIESKVNKIYQNFYSERDNQYKDRLTALQTDLTSLHQGDNGQYARQVRD 68

Query: 92  XXXXXXXXXXXXXXXXXXXIYRSKVEFQEDIEKAKQEHERMIKLCKEMLYESLQKTIKKL 151
                              + RS +EFQEDIEKAK EHE++IKLCKE LY S+++ IKKL
Sbjct: 69  LEEERDLELVRLRLFEEYRVSRSGIEFQEDIEKAKAEHEKLIKLCKERLYSSIEQKIKKL 128

Query: 152 QEERLLLDVANTQSYSMDYSRGKFQKQTRSSTQNSANFSAWDSSPNDVSQ---TESGNET 208
           QEERLL+DVAN  SY+M+YSR ++QK TRS T      S WDSS N+  +    ES  +T
Sbjct: 129 QEERLLMDVANVHSYAMNYSRPQYQKNTRSHT-----VSGWDSSSNEYGRDTANESATDT 183

Query: 209 GNTTDRRSL----XXXXXXXXXXXXXPANITPANGSGKS-------------------SN 245
           G   DRR+L                  ++    NGSG +                   S 
Sbjct: 184 GAGNDRRTLRRRNASKDTRGNNNNQDESDFQTGNGSGSNGHGSRQGSQFPHFNNLTYKSG 243

Query: 246 TNSDAESMQYLSDSSELQALLFGXXXXXXXXMG------RGHQRLSTKSAPILQSLTPDE 299
            NSD++ +Q +++ ++L A LFG         G      RG QR STK+AP LQSL PDE
Sbjct: 244 MNSDSDFLQGINEGTDLYAFLFGEKNPKDNANGNEKKKNRGAQRYSTKTAPPLQSLKPDE 303

Query: 300 VTDDISLIRKLTGQVPAPFK 319
           VT+DISLIR+LTGQ PAPF+
Sbjct: 304 VTEDISLIRELTGQPPAPFR 323


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.309    0.126    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,955,207
Number of Sequences: 60738
Number of extensions: 456421
Number of successful extensions: 1635
Number of sequences better than 1.0e-05: 1
Number of HSP's better than  0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1631
Number of HSP's gapped (non-prelim): 1
length of query: 319
length of database: 30,389,216
effective HSP length: 106
effective length of query: 213
effective length of database: 23,950,988
effective search space: 5101560444
effective search space used: 5101560444
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)