ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2337 good YU KOG1964 Intracellular trafficking, secretion, and vesicular transport Nuclear pore complex, rNup107 component (sc Nup84)
r_klactV2337 good YU KOG1964 Nuclear structure Nuclear pore complex, rNup107 component (sc Nup84)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2337 812175 814340 722
(722 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL116w [YU] KOG1964 Nuclear pore complex rNup107 component (sc ... 625 e-179
SPBC428.01c [YU] KOG1964 Nuclear pore complex rNup107 component ... 166 2e-40
Hs9966881 [YU] KOG1964 Nuclear pore complex rNup107 component (s... 86 2e-16
>YDL116w [YU] KOG1964 Nuclear pore complex rNup107 component (sc Nup84)
Length = 726
Score = 625 bits (1611), Expect = e-179
Identities = 308/724 (42%), Positives = 485/724 (66%), Gaps = 5/724 (0%)
Query: 1 MDVDFNRSQETHLKFGQILKEYQARVLSDEASLDPFSIVQDFRXXXXXXXXXXXXXXXXN 60
M++ E KF LKE++ +++ +DPF+I+++FR +
Sbjct: 1 MELSPTYQTERFTKFSDTLKEFKIEQNNEQNPIDPFNIIREFRSAAGQLALDLANSGDES 60
Query: 61 DNEQFQNWELEAKFWDLVGLLVEYRTSETVDKDINVHSYNSNVVFQKQLLQSNKGIYEIW 120
+ ++WELEA+FW LV LL+ +R ++ ++ +H YNS +F+K+L+Q NK +Y+IW
Sbjct: 61 NVISSKDWELEARFWHLVELLLVFRNADLDLDEMELHPYNSRGLFEKKLMQDNKQLYQIW 120
Query: 121 LIKSWLEANIGIPERPSSLCTTKWSSSMIAGTVKSMDSDSILRDPTTNLQPDDRQNDHAF 180
++ WL+ N + ERP ++ T+KW +S+ +G +KS D D LR+ T L D++ DH F
Sbjct: 121 IVMVWLKENTYVMERPKNVPTSKWLNSITSGGLKSCDLDFPLRENTNVLDVKDKEEDHIF 180
Query: 181 FVYAFRLLLAGQFEKLTEECEFTDNLTLNLILRGMESYVDPNVDTDMTDEYASQQGIKKH 240
F Y + L+LAG ++ EE + +DN+++ +IL G++ Y++P +DT + +E+ +QQGIKKH
Sbjct: 181 FKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEYLNPVIDTQIANEFNTQQGIKKH 240
Query: 241 ALWRRSVYALSQDPLLDPYEAAIYTYLSGDSPTNLRIDGLDWETELLIYVNQIWNVTMEN 300
+LWRR+VY+LSQ LDPYE AIY+YLSG P + DWE++L I++NQI +EN
Sbjct: 241 SLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEVLQYSDWESDLHIHLNQILQTEIEN 300
Query: 301 YLIEHGRVDNDELITDMDTACPSLSQVLNILAAKYPDESEHPIRVLTASVLLNTIEPVMK 360
YL+E+ +V DELI + + ++ +VLN +A+++P ESEHPIRVL ASV+L+++ V+
Sbjct: 301 YLLENNQVGTDELILPLPSHALTVQEVLNRVASRHPSESEHPIRVLMASVILDSLPSVIH 360
Query: 361 SSTDMLLDVIKGRDEDNALFNESYLLRILTNLTIFLDIVSPDTIDISNKXXXXXXXXXXX 420
SS +MLLDV+KG + N + ++ YLLRI+T+L I LDI++P +++ +K
Sbjct: 361 SSVEMLLDVVKGTEASNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLL 420
Query: 421 XXXXXXDVIPVFVSFLSQEEIVETYSFFLTNLIDPNLRQKQMEISKYLGLPIANILRRTA 480
+ IP++ +FL++ + +E SF L++L DP +R+KQ+E +L LP +NILRRT
Sbjct: 421 KLQGLYENIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTT 480
Query: 481 QRIFEETDQYYIVDSDIELTNEVSEVDQRLMNGVEWLIENGLYTDSIDTIIALSRRFLIN 540
QR+F+ET+Q Y ++I ++ +V+ +D L+ GVEWLIE LY D++ +IIALSRRFL+N
Sbjct: 481 QRVFDETEQEYSPSNEISISFDVNNIDMHLIYGVEWLIEGKLYVDAVHSIIALSRRFLLN 540
Query: 541 GKVKALELFVDNHDVPNLLKEYQLERLS---SQEEDHDLKTTELLQYTSLLSTFKKQEEW 597
G+VKALE F++ +++ + K Y+LE+++ S++E+ D E+ QY L+ ++ EEW
Sbjct: 541 GRVKALEQFMERNNIGEICKNYELEKIADNISKDENEDQFLEEITQYEHLIKGIREYEEW 600
Query: 598 VKSSQLFNTESNLRSLIKQFKGFSNTIIKLVTTFLVDLIDNEEVNDSD--VLYEIRALYT 655
KS L ++ESN+ +LI++ +GFS +L+ TFLVDL + + +D +LYEIRALYT
Sbjct: 601 QKSVSLLSSESNIPTLIEKLQGFSKDTFELIKTFLVDLTSSNFADSADYEILYEIRALYT 660
Query: 656 PFLIMELHNNLISASENLKVSTFVQEAIDLSILVANETDKIYLLFQSNGKLTTYLQMVAK 715
PFL+MELH L+ A++ LK+ F+ EA+ + LVANE DKIYLLFQS+GKL YL +VA+
Sbjct: 661 PFLLMELHKKLVEAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVAR 720
Query: 716 ASAL 719
+ L
Sbjct: 721 TATL 724
>SPBC428.01c [YU] KOG1964 Nuclear pore complex rNup107 component (sc Nup84)
Length = 780
Score = 166 bits (419), Expect = 2e-40
Identities = 175/708 (24%), Positives = 304/708 (42%), Gaps = 76/708 (10%)
Query: 60 NDNEQFQNWELEAKFWDLVGLLVEYRTSETVDKDINVHSYNSNVVFQKQLLQSNKGIYEI 119
+D E + W+LE++ WDL+ L +R SE I H+++S V +++ N +E
Sbjct: 84 DDEEWIELWDLESRTWDLIQRLYSFRLSEQ-QGHIQSHAFSSRAVLEEEYYSQNPEAFEN 142
Query: 120 WLIKSWLEANIGIPERPS-SLCTTKWS----------------SSMIAGTVKS-MDSDSI 161
++ +W N P PS + +W SS I+GT+ S +D D+
Sbjct: 143 NIVFNWARDNSSDP--PSIEIRGNRWFYTREDIKMKNRGGSRFSSNISGTIVSNLDPDAD 200
Query: 162 LRDPTTNLQPDDRQNDHAFFVYAFRLLLAGQFEKLTEECEFTDNLTLNLILRGMESYVDP 221
+RD L D + FF AF L +G FE+L E C T N + L+G+ Y D
Sbjct: 201 IRDDK-RLDERDDNFERQFFHTAFCLFRSGSFEELLELCRRTGNHWRSASLQGILEYRDN 259
Query: 222 NVDTDMTDEYASQQGIKKHALWRRSVYALSQDPLLDPYEAAIYTYLSGDSPTNLRIDGLD 281
+D + E + G K+ L RRS AL+++ +D YE A+Y L GD + L +
Sbjct: 260 LIDDVLQSETS---GNKRKELLRRSCLALTKNKRIDSYERALYGALCGDLNSVLDVC-TT 315
Query: 282 WETELLIYVNQIWNVTMENYLIEHGRVDNDELITDMDTAC---PSL--SQVLNILAAKYP 336
WE + Y N + ++ YL +L +D+ P L + + N A
Sbjct: 316 WEDAMWAYYNSMTQYNLDVYLSSKAPQTETQL-PPVDSGLGLTPELIFNSLSNSSIASIQ 374
Query: 337 DESEHPIRVLTASVLLNTIEPVMKSSTDMLLDVIKGRDEDNALFNESYLLRILTNLTIFL 396
+E+ HP+ L ++ N I ++ S+ L + G ++ LLRILT++ +FL
Sbjct: 375 EEASHPLIKLQTHIICNKISEILSSAHIQLEAIRTGNAPESGDLVTPPLLRILTHIILFL 434
Query: 397 DIVSPDTIDISNKXXXXXXXXXXXXXXXXXDVIPVFVSFLSQEEIVETYSFFLTNLIDPN 456
I S +D +++P+++ +LS + E YS FL + + +
Sbjct: 435 KI-SGLAVDEYTSDSIIQAYIELLASAKKVNLVPLYIQYLSNQVQYEAYSRFLILVDEES 493
Query: 457 LRQKQMEISKYLGLPIANILRRTAQRIFEET------DQYYIVDSDIELTNEVSEVDQRL 510
R +Q++++K L I + + +++E + + + IE E S ++L
Sbjct: 494 ARSEQLQLAKKYSLDINHAALLAVEYVYDEVVSVSPEEVHTVYLKSIEEPVEPSY--KKL 551
Query: 511 MNGVEWLIENGLYTDSIDTIIALSRRFLINGKVKALELFVDNHDVPNLLKEYQLERLSSQ 570
+ +EWL+ + + + R FL G++ + +D+ + L LSS
Sbjct: 552 ICTLEWLLITSQTDELLRFANLVYRFFLSIGELNSA------YDLYTHIPSDALNTLSSS 605
Query: 571 --EEDHDLK---TTELLQYTSLLSTFKKQEEW--------VKSSQLFNTESNLRSLIKQF 617
E ++D K EL+ Y +L K +EW + S + ++ + K+
Sbjct: 606 DGEPENDSKFRDAYELMNYRALCRALKFYQEWEELSKQEVFEDSAVTKASTSYKVWKKKL 665
Query: 618 KGFSNTIIKLVTTFL---------VDLIDNEEVNDSDVLYEIRALYTPFLIMELHNNLIS 668
S +K T L ++L +++ L IR LY P LI+ LHN S
Sbjct: 666 NFASRKCVKSFTDLLQANWLHPSTLELKPDDDPLLYKTLMTIRNLYVPELILGLHNVYFS 725
Query: 669 ASENLKVSTFVQEAIDLSILVANETDKIYLLFQSNGKLTTYLQMVAKA 716
+ L+ VA+E K+Y +G+L Y+ + KA
Sbjct: 726 LED-------YDSCFALANEVASEDLKLYHCLIKSGRLVEYVSYLGKA 766
>Hs9966881 [YU] KOG1964 Nuclear pore complex rNup107 component (sc Nup84)
Length = 925
Score = 86.3 bits (212), Expect = 2e-16
Identities = 132/617 (21%), Positives = 254/617 (40%), Gaps = 76/617 (12%)
Query: 153 VKSMDSDSILRDPTTNLQPDDRQNDHAFFVYAFRLLLAGQFEKLTEECEFTDNLTLNLIL 212
V +D D+ +R L DR+++ Y F L+ AG E+ C+ L
Sbjct: 320 VTELDPDAPIRQKMP-LDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATL 378
Query: 213 RGMESYVDPNVDTDMTDEYASQQGIKKHALWRRSVYALSQDPLLDPYEAAIYTYLSGDSP 272
G + Y DPNV+ E +G +W+ S + +++D L + YE AIY LSG+
Sbjct: 379 EGWKLYHDPNVNGGT--ELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLK 436
Query: 273 TNLRIDGLDWETELLIYVNQIWNVTMENYLIEHGRV--DNDELITDMDTACPSLSQVLNI 330
L + WE + Y + + +E + + +EL + A +L +V
Sbjct: 437 QLLPVCD-TWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEE 495
Query: 331 LAA----KYPDESEHPIRVLTASVLLNTIEPVMKSSTDMLLDVIKGRDEDNALFNESYLL 386
L A + +E++ ++ ++L I+ +M + L + +N +LL
Sbjct: 496 LQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWL-----SKSRNNL---PGHLL 547
Query: 387 RILTNLTIFLDIVSPDTIDISNKXXXXXXXXXXXXXXXXXDVIPVFVSFLSQEEIVETYS 446
R +T+L +F + T + ++I + L Q+ V Y+
Sbjct: 548 RFMTHLILFFRTLGLQTKE-EVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYA 606
Query: 447 FFLTNLIDPNLRQKQMEISKYLGLPIANILRRTAQRI-FEETDQYYIVDSDIELTNEVSE 505
FL ++ + R +E++K L +A I + + I ++ ++ D L +E
Sbjct: 607 LFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTE 666
Query: 506 VDQRLMNGVEWLI-ENGLYTDSIDTIIALSRRFLINGKVKAL-ELFV-----DNHDVPNL 558
D+ ++ ++WL+ + +++ A+ R+FL + K +A E+FV ++ N
Sbjct: 667 EDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQ 726
Query: 559 LKEYQLERLSSQEEDHDLKTTELLQYTSLLSTFKKQEEWVKSSQLFNTESNLRSLIKQ-- 616
+E +E E+D+ ++ E L + L + EW K N+ +LI Q
Sbjct: 727 CEEQGMESPLPAEDDNAIR--EHLCIRAYLEAHETFNEWFKH---MNSVPQKPALIPQPT 781
Query: 617 --------------------FKG------------FSNTIIKLVTTFLVDLIDN--EEVN 642
+KG N ++ + ++VD+ ++ E+
Sbjct: 782 FTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHE 841
Query: 643 DSDVLYEIRALYTPFLIMELHNNLISASENLKVSTFVQEAIDLSILVANETDKIYLLFQS 702
+ + +R L P L LH L S + QE + L+ +V++E K+YL+F S
Sbjct: 842 RTHQMVLLRKLCLPMLCFLLHTILHSTGQ-------YQECLQLADMVSSERHKLYLVF-S 893
Query: 703 NGKLTTYLQMVAKASAL 719
+L LQ + ++S +
Sbjct: 894 KEELRKLLQKLRESSLM 910
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,525,812
Number of Sequences: 60738
Number of extensions: 1631556
Number of successful extensions: 4545
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 4529
Number of HSP's gapped (non-prelim): 5
length of query: 722
length of database: 30,389,216
effective HSP length: 114
effective length of query: 608
effective length of database: 23,465,084
effective search space: 14266771072
effective search space used: 14266771072
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)