ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2362 good J KOG1612 Translation, ribosomal structure and biogenesis Exosomal 3'-5' exoribonuclease complex, subunit Rrp42
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2362 825138 824347 -264
(264 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL111c [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subun... 315 5e-86
SPBC16G5.10 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex s... 78 1e-14
Hs18545020 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex su... 76 4e-14
7303006 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subun... 64 2e-10
At3g07750 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex sub... 61 1e-09
Hs22051959 [J] KOG1613 Exosomal 3'-5' exoribonuclease complex su... 49 7e-06
>YDL111c [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subunit Rrp42
Length = 265
Score = 315 bits (806), Expect = 5e-86
Identities = 153/263 (58%), Positives = 198/263 (75%), Gaps = 2/263 (0%)
Query: 1 MGLSLTEKSFLYDSLTLDPPLRPDGRGPHQFRPLEVSTDFLPNSNGSSRVILSGGSECIV 60
M LS+ EKS+LYDSL P +RPDGR PHQFRP+E+ TDFLP+SNGSSR+I S GSECIV
Sbjct: 1 MSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSECIV 60
Query: 61 SVKTKVVDHTVEQELLVADVDIQGHRDDSPLVTXXXXXXXXX--XXQTIDQKKLMLTKRY 118
S+K+KVVDH VE ELL DVDI G RDD+ +V +D KL LTK+Y
Sbjct: 61 SIKSKVVDHHVENELLQVDVDIAGQRDDALVVETITSLLNKVLKSGSGVDSSKLQLTKKY 120
Query: 119 SFKLYIDVLVLASKSYPISMISFAIFSALKNTWLPKLISNDDDLEVEELPTFHDYDMVKL 178
SFK+++DVLV++S S+P+S+ISFAI+SAL +T+LPKLIS DDLEVEELPTFHDYDMVKL
Sbjct: 121 SFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISAFDDLEVEELPTFHDYDMVKL 180
Query: 179 EADAPLLFTFAIVGDGVFVDPTFEESIVSNNGLLITWYKDKVTSPIRSVGLNNDNIKGFS 238
+ + PL+F A+VG+ + +DP ES V+NNGL+I+W K+TSPIRSV LN+ N+K F
Sbjct: 181 DINPPLVFILAVVGNNMLLDPAANESEVANNGLIISWSNGKITSPIRSVALNDSNVKSFK 240
Query: 239 QHHLEQAFKLIRQYAPHIEKALD 261
H L+Q ++ +YAP + ++L+
Sbjct: 241 PHLLKQGLAMVEKYAPDVVRSLE 263
>SPBC16G5.10 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subunit Rrp42
Length = 299
Score = 77.8 bits (190), Expect = 1e-14
Identities = 78/283 (27%), Positives = 125/283 (43%), Gaps = 20/283 (7%)
Query: 1 MGLSLTEKSFLYDSLT-LDPPLRPDGRGPHQFRPLEVSTDFLPNSNGSSRVILSGGSECI 59
M LSL E S+ + S+T +P +R DGR Q RPL D LP +NGS+RV + E +
Sbjct: 1 MQLSLPELSYTHKSITEFEPAIRNDGRSIDQLRPLSGQVDVLPGTNGSARVKWASSVEIV 60
Query: 60 VSVKTKVVDHTVEQELLVADVDIQG----HRDDSPLVTXXXXXXXXXXXQTIDQKKLMLT 115
+ VK +V D T E VA V+I ++ + + L T
Sbjct: 61 IGVKAEVGDATPEGGKYVASVEISPSVSIQNRETDEIPSFLTSALQDLLNALAVDYLKFT 120
Query: 116 KRYSFKLYID-VLVLASKSYP--ISMISFAIFSALKNTWLPKLIS-NDDDLEV--EELPT 169
++ +++D V++L+S Y +S +S A + AL+ T LPK+ + N D+ + +
Sbjct: 121 PSKAWIIHVDAVVILSSSPYENILSALSLAAYLALQTTRLPKISTPNVTDITIGSTKYEP 180
Query: 170 FHDYDM-VKLEADAPL--------LFTFAIVGDGVFVDPTFEESIVSNNGLLITWYKDKV 220
+YD+ + E PL + + + + VDPT EES V+ I
Sbjct: 181 SEEYDVDSEWENALPLQGLELMSVIILVSSIDQVIIVDPTIEESSVAQVTYAIGVQASGA 240
Query: 221 TSPIRSVGLNNDNIKGFSQHHLEQAFKLIRQYAPHIEKALDAS 263
S R VG +E+ +L+ + K L+AS
Sbjct: 241 ISYTRVVGTGGGYASTGRAITVERYIELLETASTVGTKLLNAS 283
>Hs18545020 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subunit Rrp42
Length = 291
Score = 76.3 bits (186), Expect = 4e-14
Identities = 70/241 (29%), Positives = 116/241 (48%), Gaps = 18/241 (7%)
Query: 3 LSLTEKSFLYDSLTLDPPLRPDGRGPHQFRPLEVSTDFLPNSNGSSRVILSGGSECIVSV 62
LS EK ++ + D LR DGRG +R +EV TD + N++GS+RV L G ++ +V V
Sbjct: 6 LSEAEKVYIVHGVQED--LRVDGRGCEDYRCVEVETDVVSNTSGSARVKL-GHTDILVGV 62
Query: 63 KTKVVDHTVEQ------ELLV-----ADVDIQGH-RDDSPLVTXXXXXXXXXXXQTIDQK 110
K ++ +E+ E V A + +G DD ++D K
Sbjct: 63 KAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLK 122
Query: 111 KLMLTKR-YSFKLYIDVLVLASKSYPISMISFAIFSALKNTWLPKLISNDDDLEVEELPT 169
L ++ R + + LY+DVL+L IS A+ +AL NT +P++ +D+ +++
Sbjct: 123 TLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIEL 182
Query: 170 FHD-YDMVKLEAD-APLLFTFAIVGDGVFVDPTFEESIVSNNGLLITWYKDKVTSPIRSV 227
D YD ++L + P + T +G VD T +E S LL++ V + +R V
Sbjct: 183 SDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKV 242
Query: 228 G 228
G
Sbjct: 243 G 243
>7303006 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subunit Rrp42
Length = 281
Score = 64.3 bits (155), Expect = 2e-10
Identities = 56/208 (26%), Positives = 101/208 (47%), Gaps = 16/208 (7%)
Query: 22 RPDGRGPHQFRPLEVSTDFLPNSNGSSRVILSGGSECIVSVKTKV-VDHTVEQEL--LVA 78
R DGR +RP+++ T + N++GS+R+ L+ ++ +V VKT++ V + + E L
Sbjct: 8 RCDGRSRRDYRPMDLETGLVSNASGSARLRLAN-TDILVGVKTEIDVPNPLTPEFGKLEF 66
Query: 79 DVDIQGH-------RDDSPLVTXXXXXXXXXXXQTID---QKKLMLTKRYSFKLYIDVLV 128
VD + R S L + + ++ + +KLYID+L+
Sbjct: 67 FVDCSANATPEFEGRGGSDLAQELILSLQNAYESPLAFNYRTLCLIPGQQCWKLYIDILI 126
Query: 129 LASKSYPISMISFAIFSALKNTWLPKLISNDDDLEVEEL-PTFHDYDMVKLEAD-APLLF 186
L +S A +AL NT LP++ + D + +L + + YD ++ + PLL
Sbjct: 127 LECGGNLHDAVSLAAKAALFNTKLPRVTATMLDAGITDLIISDNPYDCTRIGIETVPLLV 186
Query: 187 TFAIVGDGVFVDPTFEESIVSNNGLLIT 214
T +GD V VDP+ EE + S ++++
Sbjct: 187 TVCKIGDYVLVDPSAEEEVCSTVSMVVS 214
>At3g07750 [J] KOG1612 Exosomal 3'-5' exoribonuclease complex subunit Rrp42
Length = 293
Score = 61.2 bits (147), Expect = 1e-09
Identities = 63/245 (25%), Positives = 111/245 (44%), Gaps = 38/245 (15%)
Query: 1 MGLSLTEKSFLYDSLTLDPPLRPDGRGPHQFRPLEVSTDFLPNSNGSSRVILSGGSECIV 60
MGLSL E+ F+ + D LR DGR +RP+ V T +P +NGS+RV + GG++ I
Sbjct: 1 MGLSLGEQHFIKGGIAQD--LRTDGRKRLTYRPIYVETGVIPQANGSARVRI-GGTDVIA 57
Query: 61 SVKTKV---VDHTVEQELLVADVDIQ-------GHRDDSPLVT--------------XXX 96
SVK ++ ++ + +D G R L +
Sbjct: 58 SVKAEIGRPSSLQPDKGKVAVFIDCSPTAEPTFGGRGGEELSSELALALQRCLLGGKSGA 117
Query: 97 XXXXXXXXQTIDQKKLMLTK-RYSFKLYIDVLVLASKSYPISMISFAIFSALKNTWLPKL 155
I+ L++ + + + LYID LV++S + + AI +AL NT +PK+
Sbjct: 118 AIHVLVPGAGINLSSLLIKEGKVCWDLYIDGLVISSDGNLLDALGAAIKAALTNTAIPKV 177
Query: 156 -----ISNDDDLEVEELPTFHDYDMVKLE-ADAPLLFTFAIVGDGVFVDPTFEESIVSNN 209
+++D+ E++ D + ++ + + P++ T VG VD T EE ++
Sbjct: 178 NVSAEVADDEQPEID----ISDEEYLQFDTSSVPVIVTLTKVGTHYIVDATAEEESQMSS 233
Query: 210 GLLIT 214
+ I+
Sbjct: 234 AVSIS 238
>Hs22051959 [J] KOG1613 Exosomal 3'-5' exoribonuclease complex subunit Rrp43
Length = 276
Score = 48.9 bits (115), Expect = 7e-06
Identities = 51/206 (24%), Positives = 90/206 (42%), Gaps = 18/206 (8%)
Query: 22 RPDGRGPHQFRPLEVSTDFLPNSNGSSRVILSGGSECIVSVKTKVVDHTVE---QELLVA 78
RPDGR +FR V+ + ++GS+ V L G + I VK + + + + +V
Sbjct: 23 RPDGRELGEFRTTTVNIGSISTADGSALVKL-GNTTVICGVKAEFAAPSTDAPDKGYVVP 81
Query: 79 DVDI---------QGHRDDSPLVTXXXXXXXXXXXQTIDQKKLMLTK-RYSFKLYIDVLV 128
+VD+ G + V Q I ++ L ++ + + LY D++
Sbjct: 82 NVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLIC 141
Query: 129 LASKSYPISMISFAIFSALKNTWLPKLISNDDDLEVEELPTFHDYDMVKLEADAPLLFTF 188
L + +FA+ +ALKN LP++ N++ E Y ++ P+ +F
Sbjct: 142 LDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNIRTH---PVATSF 198
Query: 189 AIVGDG-VFVDPTFEESIVSNNGLLI 213
A+ D + VDPT EE ++ L I
Sbjct: 199 AVFDDTLLIVDPTGEEEHLATGTLTI 224
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,154,792
Number of Sequences: 60738
Number of extensions: 623834
Number of successful extensions: 1416
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1408
Number of HSP's gapped (non-prelim): 8
length of query: 264
length of database: 30,389,216
effective HSP length: 104
effective length of query: 160
effective length of database: 24,072,464
effective search space: 3851594240
effective search space used: 3851594240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)