ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2378 good A KOG2769 RNA processing and modification Putative u4/u6 small nuclear ribonucleoprotein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2378 828244 829515 424
(424 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR473c [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein 291 1e-78
SPAC29E6.02 [A] KOG2769 Putative u4/u6 small nuclear ribonucleop... 154 3e-37
CE03498 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein 144 2e-34
At1g28060 [A] KOG2769 Putative u4/u6 small nuclear ribonucleopro... 144 3e-34
Hs4758556 [A] KOG2769 Putative u4/u6 small nuclear ribonucleopro... 135 9e-32
At3g55930 [A] KOG2769 Putative u4/u6 small nuclear ribonucleopro... 125 9e-29
7293728 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein 119 7e-27
Hs22049844_1 [A] KOG2769 Putative u4/u6 small nuclear ribonucleo... 77 4e-14
>YDR473c [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 469
Score = 291 bits (746), Expect = 1e-78
Identities = 168/427 (39%), Positives = 234/427 (54%), Gaps = 22/427 (5%)
Query: 10 GLNRKLHSALSVENVNLLRFQGRRCGNPYLQDVQAHG----FEPKARVSSHWYEPGEVVQ 65
GL +LHSAL N+NL+R + NPYL D G F + +Y+ GE+ +
Sbjct: 41 GLKTELHSALKSSNLNLIRRTYQTGENPYLSDPHDRGSSSRFNRRYERGLKFYQKGEISK 100
Query: 66 HAAKLRQENXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLP--DKHEEVYFTDLSDVP--- 120
A+ R LP + HE+ + DLS
Sbjct: 101 RIAQERTLQKQQEEEELKRKLKQEEDEKDKRKLIESGDLPNLELHEDKFLLDLSKFKIYY 160
Query: 121 ----DVEWWDVPYIKD-GSIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQH 175
EWWD Y+ + G + EKY ++ T D+ PSIRY+ H
Sbjct: 161 DNNHGYEWWDTAYLDEKGELMEKYDMN-GTSPAEEKLAEDIDEVDDDDDDEHPSIRYVAH 219
Query: 176 PVPIERPRAAVPVAEIFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNMM 235
P+P + A V + + +LT++ERK+ RRN RK+ R+ +E KIKLG+ PKPEPKVKLSNMM
Sbjct: 220 PLPEKINEAKVSI-KAYLTQHERKRLRRNRRKMAREAREIKIKLGLLPKPEPKVKLSNMM 278
Query: 236 NVYENDANIADPTQWESIVRRQVAERKRKHFEENEIRHQESLKRRKESQLQAHSNDSPLE 295
+V+END NI DPT WE +V+ QV RKRKH EENE RH++++KRRKE+ + + P
Sbjct: 279 SVFENDQNITDPTAWEKVVKDQVDLRKRKHLEENERRHEDAIKRRKEAVNM--NVEKPTV 336
Query: 296 YTCVVYMFDEIQNPSIRYKIKTNGKQLKLKGCCLHIQ-NGKGIIVAFGDEKSIRFFDKLV 354
Y C V+ F +QNP IR+K+K N K+L LKG CL I+ +G GII+ G+EKS +F++ LV
Sbjct: 337 YHCKVFQFKNLQNPKIRFKLKMNSKELSLKGLCLRIRDDGPGIIIVVGNEKSCKFYENLV 396
Query: 355 TKRINWSEPYKDRDTEETVPCD---GKITKVWQGLIGDCRFKGWFMLDCKDKNQLNNILE 411
KRI W+E ++ + D I+K W+G + DC+FKGWFM C D++ L L
Sbjct: 397 MKRIKWNEDFELHTNTGDIKMDMHNNSISKTWEGYLQDCKFKGWFMKVCNDQDSLLRTLG 456
Query: 412 QHDALTF 418
Q D+ F
Sbjct: 457 QFDSEHF 463
>SPAC29E6.02 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 542
Score = 154 bits (388), Expect = 3e-37
Identities = 105/307 (34%), Positives = 155/307 (50%), Gaps = 34/307 (11%)
Query: 119 VPDVEWWDVPYIKDGSIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQHPVP 178
+P++EWWD+P+IKD + DY N G Q S IQHP+P
Sbjct: 239 IPNIEWWDLPFIKDYN-------DYGDENNWLID---------GPQSIINSA--IQHPIP 280
Query: 179 IERPRAAVPVAE--IFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNMMN 236
+ P A + +FLTK E+KK RR TR R+EK+++ LGIEP PKVKLSN+M+
Sbjct: 281 VLPPYAKNQPSSHSVFLTKKEQKKIRRQTRAEARKEKQDRQLLGIEPPEPPKVKLSNLMH 340
Query: 237 VYENDANIADPTQWESIVRRQVAERKRKHFEENEIRHQESLKRRKESQLQAHSNDSPLEY 296
V +DA I DPT+ E+ VR+QV ER+ +H ENE R + + + RKE + DS
Sbjct: 341 VLGDDA-IKDPTKIEAEVRKQVEERRLRHERENEER-KLTPEERKEKAFRKKDEDSAAGL 398
Query: 297 TCVVYMFDEIQNPSIRYKIKTNGKQLKLKGCCLHIQNGKGIIVAFGDEKSIRFFDKLVTK 356
C+V+ + + R KI N KQ G C+ N +I G +K+I+ +L+ +
Sbjct: 399 RCLVFRIKYLAHRPHRLKIDLNAKQWGATGVCILNANFNLVIFEAG-QKAIKKLKRLMLE 457
Query: 357 RINWSEPYK-----------DRDTEETVPCDGKITKVWQGLIGDCRFKGWFMLDCKDKNQ 405
RI+W++ + D + E + VW+G IG F+ W C +N
Sbjct: 458 RIDWTDTSRNSIIAQGNKLVDTEGRELNYTENTCNLVWEGEIGRRAFRYWSFRSCPSEND 517
Query: 406 LNNILEQ 412
+ LE+
Sbjct: 518 AKSYLEE 524
>CE03498 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 621
Score = 144 bits (364), Expect = 2e-34
Identities = 96/309 (31%), Positives = 156/309 (50%), Gaps = 44/309 (14%)
Query: 119 VPDVEWWDVPYIKDGSIHE--------KYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSI 170
VPD+EWWD+ + + E +YS S L
Sbjct: 318 VPDIEWWDMLVLDKVNYDEIPAENDMERYSQTVSEL------------------------ 353
Query: 171 RYIQHPVPIERPRAAVP--VAEIFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPK 228
++HP+ + P + +++LT E+KK RR RK V +EK EKI+LG+E PEPK
Sbjct: 354 --VEHPISMRAPTEPLTQQYLKVYLTTKEKKKIRRQNRKEVLKEKTEKIRLGLEKAPEPK 411
Query: 229 VKLSNMMNVYENDANIADPTQWESIVRRQVAERKRKHFEEN-EIRHQESLKRRKESQLQA 287
VK+SN+M V N+A I DPT+ E+ VR+Q+AER +KH N E + E KR K++ +
Sbjct: 412 VKISNLMRVLGNEA-IQDPTKMEAQVRKQMAERLKKHETLNAERKLTEDQKRAKKT--KK 468
Query: 288 HSNDSPLEYTCVVYMFDEIQNPSIRYKIKTNGKQLKLKGCCLHIQNGKGIIVAFGDEKSI 347
S D+ VY + +PS ++K++TN KQL++ G + + + +IV G K
Sbjct: 469 LSEDTSTAVNVSVYRVKSLAHPSKKFKVETNAKQLQMSGAIM-MHKAQNVIVVEGGPKQQ 527
Query: 348 RFFDKLVTKRINWSEPY--KDRDTEETVPCDGKITK-VWQGLIGDCRFKGWFMLDCKDKN 404
+F+ L+ RI WS+ + +D E+ P + + + +W+G + F+ + + +
Sbjct: 528 KFYKNLMINRIKWSDEIIGQKKDAEKDAPGERNLCEMIWEGQVKRRNFRDFTVHTATLEK 587
Query: 405 QLNNILEQH 413
Q E+H
Sbjct: 588 QAREFFEKH 596
>At1g28060 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 786
Score = 144 bits (362), Expect = 3e-34
Identities = 89/287 (31%), Positives = 143/287 (49%), Gaps = 23/287 (8%)
Query: 119 VPDVEWWDVPYIKDGSIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQHPVP 178
+PDVEWWD + +G E + T+ YI+HP P
Sbjct: 490 IPDVEWWDANVLTNGEYGE---ITDGTITESHLKIEKLT-------------HYIEHPRP 533
Query: 179 IERPRAAVPVAE--IFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNMMN 236
IE P A P + LTK E+KK R R +EK+E I+ G+ P+ KVK+SN+M
Sbjct: 534 IEPPAEAAPPPPQPLKLTKKEQKKLRTQRRLAKEKEKQEMIRQGLLEPPKAKVKMSNLMK 593
Query: 237 VYENDANIADPTQWESIVRRQVAERKRKHFEENEIRHQESLKRRKESQLQAHSNDSPLEY 296
V ++A DPT+ E +R AER++ H + N R ++R++ + + + + +E
Sbjct: 594 VLGSEAT-QDPTKLEKEIRTAAAEREQAHTDRNAARKLTPAEKREKKERKLFDDPTTVET 652
Query: 297 TCVVYMFDEIQNPSIRYKIKTNGKQLKLKGCCLHIQNGKGIIVAFGDEKSIRFFDKLVTK 356
VY ++ +P R+K++ N ++ +L GC + + + ++V G K+I+ + KL+ K
Sbjct: 653 IVSVYKIKKLSHPKTRFKVEMNARENRLTGCSV-MTDEMSVVVVEGKSKAIKRYGKLMMK 711
Query: 357 RINWSEPYK---DRDTEETVPCDGKITKVWQGLIGDCRFKGWFMLDC 400
RINW E + + D EE V K VWQG IG F + + +C
Sbjct: 712 RINWEEAERKEGNEDEEEEVNGGNKCWLVWQGSIGKPSFHRFHVHEC 758
>Hs4758556 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 683
Score = 135 bits (341), Expect = 9e-32
Identities = 92/307 (29%), Positives = 147/307 (46%), Gaps = 32/307 (10%)
Query: 118 DVPDVEWWDVPYIKDGSIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQHPV 177
D+P++EWWD I +G D + N +D F ++HP
Sbjct: 383 DIPEIEWWDSYIIPNG-------FDLTEENPKR-------------EDYFGITNLVEHPA 422
Query: 178 PIERP-RAAVPVA-EIFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNMM 235
+ P PV ++LTK E+KK RR TR+ ++E +EK++LG+ P PEPKV++SN+M
Sbjct: 423 QLNPPVDNDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLM 482
Query: 236 NVYENDANIADPTQWESIVRRQVAERKRKHFEENEIRHQESLKRRKESQLQAHSNDSPLE 295
V +A + DPT+ E+ VR Q+A+R++ H E N R + + ++RK +++ D
Sbjct: 483 RVLGTEA-VQDPTKVEAHVRAQMAKRQKAHEEANAAR-KLTAEQRKVKKIKKLKEDISQG 540
Query: 296 YTCVVYMFDEIQNPSIRYKIKTNGKQLKLKGCCLHIQNGKGIIVAFGDEKSIRFFDKLVT 355
VY + NP+ ++KI+ N QL L G + + ++V G K+ + F +L+
Sbjct: 541 VHISVYRVRNLSNPAKKFKIEANAGQLYLTGVVV-LHKDVNVVVVEGGPKAQKKFKRLML 599
Query: 356 KRINWSEPYK-------DRDTEETVPCDGKITKVWQGLIGDCRFKGWFMLDCKDKNQLNN 408
RI W E + EE V K VW+G D F C +N
Sbjct: 600 HRIKWDEQTSNTKGDDDEESDEEAVKKTNKCVLVWEGTAKDRSFGEMKFKQCPTENMARE 659
Query: 409 ILEQHDA 415
++H A
Sbjct: 660 HFKKHGA 666
>At3g55930 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 437
Score = 125 bits (315), Expect = 9e-29
Identities = 88/291 (30%), Positives = 139/291 (47%), Gaps = 17/291 (5%)
Query: 123 EWWDVPYIKDGSIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQHPVPIERP 182
EWWD + D +I+E S D + L +I+HP PIE P
Sbjct: 144 EWWDAKILTDDTINE-LSCDPNILIMDTITENHLNMKVFNC--------HIEHPFPIEPP 194
Query: 183 RAAV--PVAEIFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNMMNVYEN 240
A P + +TK ERKK R R EK E I G + KVK+SN+M V +
Sbjct: 195 AEAASPPPQPLKMTKEERKKLRTLRRVAKEMEKREMISQGRVEPQKSKVKMSNLMKVRAS 254
Query: 241 DANIADPTQWESIVRRQVAERKRKHFEENEIRHQESLKRRKESQLQAHSNDSPLEYTCV- 299
+A +PT+ E +R + AER++ H + N R ++R++ + + + + + T V
Sbjct: 255 EAT-QNPTKLEKEIRTEAAEREQAHMDRNVARKLTPAEKREKKERKLFGDPTTVVETIVS 313
Query: 300 VYMFD-EIQNPSIRYKIKTNGKQLKLKGCCLHIQNGKGIIVAFGDEKSIRFFDKLVTKRI 358
VY + ++ +P R+K++ N KQ L G + + +G ++V G K+I ++KL+ KRI
Sbjct: 314 VYKINKKLSDPKTRFKVRMNAKQNILTGFSV-MMDGMSVVVVEGKRKAINRYEKLMLKRI 372
Query: 359 NWSEPYKDRDTEETVPCDGKITKVWQGLIGDCRFKGWFMLDCKDKNQLNNI 409
NW E K D EE K VWQG + F + + +C K+ +
Sbjct: 373 NWEEAEKKEDEEEN--GGNKCCLVWQGSVEKPSFHRFHVQECLTKSDAKKV 421
>7293728 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 598
Score = 119 bits (299), Expect = 7e-27
Identities = 85/290 (29%), Positives = 138/290 (47%), Gaps = 43/290 (14%)
Query: 118 DVPDVEWWDVPYIKDGSIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQHPV 177
DVP +EWWD + D T++ I+HP
Sbjct: 301 DVPAMEWWDSVILTQ---------DLETVDDASGKISIRQTAITNL---------IEHPT 342
Query: 178 PIERPRAAV-PV-AEIFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNMM 235
++ P + PV +FLTK ERKK RR R+ +E++EKI+LG+ PEPK+++SN+M
Sbjct: 343 QMKPPNEPLKPVYLPVFLTKKERKKLRRQNRREAWKEEQEKIRLGLVAPPEPKLRISNLM 402
Query: 236 NVYENDANIADPTQWESIVRRQVAERKRKHFEENEIRHQESLKRRKESQLQAHSNDSPLE 295
V ++A + DPT+ E VR Q+A+R++ H + N R S ++ ++ Q + + S
Sbjct: 403 RVLGSEA-VQDPTKMEQHVRDQMAKRQKAHEDANNARKLTSEQKSEKKQRKLREDTSCGV 461
Query: 296 YTCVVYMFDEIQNPSIRYKIKTNGKQLKLKG-------CCLHIQNGKGIIVAFGDEKSIR 348
+ V + D N S ++K++TN KQL++ G CC ++V G K +
Sbjct: 462 HVSVYRIRDLQDNQSKKFKVETNAKQLQMTGSVVLFRDCC--------VVVVEGGPKQQK 513
Query: 349 FFDKLVTKRINWSEPYKDRDTEETVPCDGKITKVWQGL-----IGDCRFK 393
+ +L+ RI W E + + VP VW+G G+ +FK
Sbjct: 514 KYRRLMLTRIKWEEDNAKGNDGQDVP--NSCVLVWEGTSQRRHFGEIKFK 561
>Hs22049844_1 [A] KOG2769 Putative u4/u6 small nuclear ribonucleoprotein
Length = 862
Score = 77.4 bits (189), Expect = 4e-14
Identities = 51/170 (30%), Positives = 85/170 (50%), Gaps = 28/170 (16%)
Query: 118 DVPDVEWWDVPYIKDG-SIHEKYSLDYSTLNXXXXXXXXXXXXXXGAQDKFPSIRYIQHP 176
D+P++EWWD I +G ++ E+ +D F ++HP
Sbjct: 376 DIPEIEWWDSYIIPNGFNLREENPK---------------------REDYFGITNLVEHP 414
Query: 177 VPIERP-RAAVPVA-EIFLTKNERKKARRNTRKLVRQEKEEKIKLGIEPKPEPKVKLSNM 234
+ P PV ++LTK E+KK +R TR+ ++E EK++LG+ P PEPKV++SN+
Sbjct: 415 AQLNAPVDNDTPVTLGVYLTKKEQKKLQRQTRREAQKELLEKVRLGLMPPPEPKVRISNL 474
Query: 235 MNVYENDANIADPTQWESIVRRQ---VAERKRKHFEENEIRHQESLKRRK 281
M V +A + DPT+ ++V + ++K KH + I+ E K
Sbjct: 475 MRVLGTEA-VQDPTKGVNVVVVEGGPKTQKKLKHLMLHRIKWDEQTSNTK 523
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,301,551
Number of Sequences: 60738
Number of extensions: 1054496
Number of successful extensions: 3957
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3919
Number of HSP's gapped (non-prelim): 12
length of query: 424
length of database: 30,389,216
effective HSP length: 109
effective length of query: 315
effective length of database: 23,768,774
effective search space: 7487163810
effective search space used: 7487163810
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)