ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2390 good IU KOG2308 Intracellular trafficking, secretion, and vesicular transport Phosphatidic acid-preferring phospholipase A1, contains DDHD domain
r_klactV2390 good IU KOG2308 Lipid transport and metabolism Phosphatidic acid-preferring phospholipase A1, contains DDHD domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2390 834076 832190 -629
(629 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR022c [IU] KOG2308 Phosphatidic acid-preferring phospholipase ... 503 e-142
SPAC20G8.02 [IU] KOG2308 Phosphatidic acid-preferring phospholip... 248 2e-65
7297347_2 [IU] KOG2308 Phosphatidic acid-preferring phospholipas... 116 1e-25
Hs22048186 [IU] KOG2308 Phosphatidic acid-preferring phospholipa... 112 2e-24
SPCC1020.13c [IU] KOG2308 Phosphatidic acid-preferring phospholi... 105 2e-22
At1g31480 [IU] KOG2308 Phosphatidic acid-preferring phospholipas... 90 9e-18
CE07393 [IU] KOG2308 Phosphatidic acid-preferring phospholipase ... 82 2e-15
Hs6005824 [IU] KOG2308 Phosphatidic acid-preferring phospholipas... 75 4e-13
Hs4758926 [IT] KOG3668 Phosphatidylinositol transfer protein 58 5e-08
Hs20553175 [IT] KOG3668 Phosphatidylinositol transfer protein 55 3e-07
7292924 [IT] KOG3668 Phosphatidylinositol transfer protein 53 1e-06
Hs13654296 [IT] KOG3668 Phosphatidylinositol transfer protein 51 5e-06
>YOR022c [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 715
Score = 503 bits (1294), Expect = e-142
Identities = 290/680 (42%), Positives = 402/680 (58%), Gaps = 96/680 (14%)
Query: 18 WFYAIDIPKTKPFESEYVPKTAPLKFQPFSKVDSKRIEDLYTQKNFSRKLDVNEDHLFEV 77
WFYAID+P +KP+ Y +P KF+PFS DS R+E +++ R + VNED+LF+V
Sbjct: 29 WFYAIDVPNSKPYLPTYQTLHSPKKFKPFSVDDSNRLEKA-SKRQERRPVLVNEDYLFKV 87
Query: 78 DLEKFSMNPIYWDGPSYEIRRGIWFDDQNRPLSHDLTKAIEELHQQWLSRDKEKSKTT-- 135
DL ++P YW+GP+Y++RRG+WFD N+PLS DLT IE L++Q D TT
Sbjct: 88 DLSHMELSPTYWEGPTYQVRRGVWFDSSNQPLSSDLTSEIEGLYKQLKFDDSNDDPTTTP 147
Query: 136 --ELRDIFRLP----------------------KDSKWKYVMFFEDDRTAFLLPDIYGGH 171
E +DIFRL +S +K+++F + +TAFLL D+ GG
Sbjct: 148 PAESQDIFRLKGKYPVDKENEGEQKNGSSNKDENESTFKFILF-ANKQTAFLLSDLDGGK 206
Query: 172 LQLTILRSSVAQLIQLGASKLTKGYEEPSSLTER--------AKEIEGQVIEHAMGLG-- 221
LQL LRS++AQ + + A+ +T+ Y+ SS T + AK + +V + +
Sbjct: 207 LQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKSR 266
Query: 222 ----KISDMIS--WEFSDLVKFPNEENNSKQEEDM--MKDEMSKDYDNGDSSE------- 266
K+ +S + SD ++ N N SK ++D ++ +M DY+N D+S+
Sbjct: 267 SIETKLEKKVSNLFNLSDFLQLFNG-NASKDQDDAQSLEKQMETDYNNADNSQGANASSK 325
Query: 267 --------------KSHYRPTNHLVLCVHGIGQNLGKKYQYVNFAHTVNLLRNNIKYLYK 312
+S+ R ++L+LCVHGIGQ LGKKY+YVNFAHTVNLLR+N+K +Y
Sbjct: 326 IEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYN 385
Query: 313 SNPSLQEFNSARKFPDYKTNSGTQVLPITWRHAIGFXXXXXXXXXXXXXLPTLADLTVDG 372
++ LQ N+A PDYK+N QVLPITWRH+I F LPTL+ +TV+G
Sbjct: 386 NSEKLQSLNTA---PDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNG 442
Query: 373 IRPLRKLLGDVGLDILLYGDDFYLDRILKHVTNELNDVYEKYREHNPEFDGKVSLLGHSL 432
+ PLRKLL D LDILLY + +Y D IL+ VT++LN Y ++E NPEFDGKV L+GHSL
Sbjct: 443 VLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFDGKVHLVGHSL 502
Query: 433 GSVILFDILSQQSKFPLNFEVDNFFAIGSPIGVFKLIQRTKIGES-------DSSTRQQT 485
GS+ILFDILS+Q K+ L F+VDN F IGSPIG+ KLIQRTKIG+ + Q
Sbjct: 503 GSMILFDILSKQKKYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQR 562
Query: 486 PACNNFYNLFHPCDPISYRVEPLIDKVTANYEAEWIPHAT-GYDFIADTVK--------- 535
P C + YN++H CDPISYR+EPL+ K A+YE ++PH + Y + ++
Sbjct: 563 PQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFGENIWKDL 622
Query: 536 ------NLMSDKNLKEKE--LMTQXXXXXXXXXXXXGRVDYSFQPNLLDVDVWSAIKSHV 587
NL S K EK+ +++ GR+DY+ P+LL+VD SAIKSHV
Sbjct: 623 PGTDENNLQSKKTSPEKKEVKLSENLTRMLTGLNYTGRLDYAMSPSLLEVDFISAIKSHV 682
Query: 588 SYFEDMDTAGFLLKEILKKH 607
SYFE+ D A F+LKEIL KH
Sbjct: 683 SYFEEPDIAAFILKEILSKH 702
>SPAC20G8.02 [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 757
Score = 248 bits (633), Expect = 2e-65
Identities = 197/686 (28%), Positives = 296/686 (42%), Gaps = 123/686 (17%)
Query: 17 RWFYAIDIPKTKPFESEYVPKTAPLKFQPFSKVDSKRIEDLYTQK----NFSRKLDVNED 72
RWFYA+D P K K A F PFS DS+ IE Y + S ++VNED
Sbjct: 97 RWFYAVDRPLRKSRTGPTEIKKAK-NFLPFSAEDSEHIEKSYLKAVENDGQSEPVNVNED 155
Query: 73 HLFEVDLEKFSMNPIYWDGPSYEIRRGIWF---DDQNRPLSHDLTKAIEELHQQWLSRDK 129
+L+ V++ ++PIYWDGP Y I RG WF D+ P +L +EE +L+
Sbjct: 156 YLYSVNVVSRELSPIYWDGPVYRILRGTWFFSRGDKLYPCEENLATQVEE---GYLNSCP 212
Query: 130 EKSKTTELRDIFRLPKDSKWKYVMFFEDDRTAFLLPDIYGGHLQLTILRSS--VAQLIQL 187
+ + E KDS +T LL GG +Q T R++ V
Sbjct: 213 YREFSNE--------KDSA------AAQSKTWALLGRYTGGFVQYTGSRNARLVYDDFYR 258
Query: 188 GASKLTKGYEEPSSLTERAKEIEGQVIEHAMGLGKISDMISWEFSDLVKFPNEENNSKQE 247
S P+S K + G ++ K S + E +L ++S
Sbjct: 259 NVSVKIMNRFSPASFHRSDKLVRGYELDMLESNSKPSTPVPTE--ELTSTTLLNDSSDPS 316
Query: 248 EDMMKDEMSKDYDNGDSSEKSHY-----RPTNHLVLCVHGIGQNLGKKYQYVNFAHTVNL 302
++ D +++ SH R NHL+LC HGIGQ +G++ + V+F ++
Sbjct: 317 DNFTPSNTESTIDLPSATDASHLMSRPDREVNHLILCCHGIGQKMGERVETVSFVKDISN 376
Query: 303 LRNNIKYLYKSNPSLQEFNSARKFPDYK-TNSGTQVLPITWRHAIGFXXXXXXXXXXX-- 359
R +K + S+P LQ +P K +G Q LP+ WR I F
Sbjct: 377 FRKTLKKTFNSSPDLQAV-----YPKLKGGGNGVQCLPLLWRQDIRFGMARDLDSSFADD 431
Query: 360 ---------------------XXLPTLADLTVDGIRPLRKLLGDVGLDILLYGDDFYLDR 398
+PTL ++ + + LR ++ DV LD+LLY Y D+
Sbjct: 432 DDDDDESLNMSRDLALDDLEDDSIPTLDNINIPTVTGLRNIISDVLLDVLLYCQPNYRDK 491
Query: 399 ILKHVTNELNDVYEKYREHNPEFDGKVSLLGHSLGSVILFDILSQQ-----SKFPLNFEV 453
IL V LN +Y Y+++ P F+G VSLLGHSLG++ILFDI+ Q SK L+F V
Sbjct: 492 ILAAVVKRLNRLYNLYKKNVPSFNGHVSLLGHSLGALILFDIIRYQGNIKYSKLQLDFPV 551
Query: 454 DNFFAIGSPIGVFKLIQRTKI---------------GESDSSTRQQTPACNNFYNLFHPC 498
NFFA+GSP+G+F+++ KI E + +C NFYN+FHP
Sbjct: 552 ANFFALGSPLGLFQMLNGKKIAGPIPKTNLTRSLSYSEQSFDSGVSILSCQNFYNIFHPT 611
Query: 499 DPISYRVEPLIDKVTANYEAEWIPHATGYDFIADT--------------------VKNLM 538
DPISYRVEPL+ K A + + I H + ++ + + N +
Sbjct: 612 DPISYRVEPLVVKQMARLKPQKISHFRPHQDLSSSGVGHKIAGGALNVLSGLRSGIANTL 671
Query: 539 SDKNLKEKELMTQXXXXXXXXX------------------XXXGRVDYSFQPNLLDV--D 578
K+L + + GR+D+ Q LD
Sbjct: 672 ILKSLSYASVFNEATADSHDESQGAENIRDWHIDERMYRLNKTGRIDFMLQEGALDTSYS 731
Query: 579 VWSAIKSHVSYFEDMDTAGFLLKEIL 604
SA+ +H Y++++D A F+L ++L
Sbjct: 732 YVSAMNAHSEYWKNVDLAHFILTQLL 757
>7297347_2 [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 707
Score = 116 bits (290), Expect = 1e-25
Identities = 93/313 (29%), Positives = 128/313 (40%), Gaps = 74/313 (23%)
Query: 266 EKSHYRPTNHLVLCVHGIGQNLGKKYQYVNFAHTVNLLRNNIKYLYKSNPSLQEFNSARK 325
E+ + +HL+ VHGIG K + V V+ R + L +S+ +
Sbjct: 228 EQGESQRVDHLLFMVHGIGSACDLKMRSVE--EVVDDFRVIAQQLVQSH--------YKN 277
Query: 326 FPDYKTNSGTQVLPITWRHAIGFXXXXXXXXXXXXXLPTLADLTVDGIRPLRKLLGDVGL 385
D +VLPI+W + L +T++ I LR D L
Sbjct: 278 STDMGLVGRVEVLPISWHGHLHSEELGIDEK--------LKSITLESIPRLRNFTNDTLL 329
Query: 386 DILLYGDDFYLDRILKHVTNELNDVYEKYREHNPEFDGKVSLLGHSLGSVILFDIL---- 441
D+L Y Y +I+ V + LNDVY KYR +PEF+G VSL GHSLGS+ILFD+L
Sbjct: 330 DVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFNGGVSLAGHSLGSLILFDLLCHQE 389
Query: 442 ---------------------SQQSKFP---------------------------LNFEV 453
SQ+ + P L F
Sbjct: 390 PLKESEEENKENPDQLPQKQSSQKVQLPTSDPLPKQVSYAMGPEGTGQPVITYTQLIFHP 449
Query: 454 DNFFAIGSPIGVFKLIQRTKIGESDSSTRQQTPACNNFYNLFHPCDPISYRVEPLIDKVT 513
FFA+GSPIG+F I+ G P C FYN+FHP DP++YR+E L++
Sbjct: 450 KKFFALGSPIGMFVTIR----GIDKLGLDFHLPTCPGFYNIFHPFDPVAYRIEALVNPDM 505
Query: 514 ANYEAEWIPHATG 526
IPH G
Sbjct: 506 NGIRPVLIPHHKG 518
>Hs22048186 [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 872
Score = 112 bits (279), Expect = 2e-24
Identities = 96/382 (25%), Positives = 156/382 (40%), Gaps = 101/382 (26%)
Query: 204 ERAKEIEGQVIEHAMGLGKISDMISWEFSDLVKFPNEENNSKQEEDM-MKDEMSKDYDNG 262
E +K I+G+ H+ L + + + W D V ++ SK + K SK +G
Sbjct: 328 EVSKSIDGKDAVHSFKLSR--NHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSG 385
Query: 263 DSSEKSHYRP---------TNHLVLCVHGIGQNLGKKYQYVNFAHTVNLLRNNIKYLYKS 313
+ + T H+V VHGIGQ + + + N + ++
Sbjct: 386 TRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQ-----------GRIIKNTAMMREA 434
Query: 314 NPSLQEFNSARKFPDYKTNSGTQVLPITWRHAIGFXXXXXXXXXXXXXLPTLADLTVDGI 373
++E R F ++ T+ + LP+ WR + T+ +T D +
Sbjct: 435 ARKIEE----RHFSNHATH--VEFLPVEWRSKLTLDGD------------TVDSITPDKV 476
Query: 374 RPLRKLLGDVGLDILLYGDDFYLDRILKHVTNELNDVYEKYREHNPEFD---GKVSLLGH 430
R LR +L +DI+ Y Y D ++K + ELN +Y + NP+F+ GKVS++ H
Sbjct: 477 RGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSH 536
Query: 431 SLGSVILFDI-------------LSQQSKFP----------------------------- 448
SLG VI +DI L ++ + P
Sbjct: 537 SLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLKEIEER 596
Query: 449 --------------LNFEVDNFFAIGSPIGVFKLIQRTKIGESDSSTR-QQTPACNNFYN 493
L F+V+NFF +GSP+ VF ++ + G + S CN N
Sbjct: 597 LHGLKASSMTQTPALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLN 656
Query: 494 LFHPCDPISYRVEPLIDKVTAN 515
+FHP DP++YR+EPLI K +N
Sbjct: 657 IFHPTDPVAYRLEPLILKHYSN 678
>SPCC1020.13c [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 669
Score = 105 bits (262), Expect = 2e-22
Identities = 83/286 (29%), Positives = 127/286 (44%), Gaps = 64/286 (22%)
Query: 276 LVLCVHGIGQNLGKKYQYVNFAHTVNLLRNNI---KYLYKSNPSLQEFNSARKFPDYKTN 332
L L VHGIGQ + + F T N+ R+ I K + K +P ++ DY+
Sbjct: 243 LFLVVHGIGQKRSETEERFLFTKTCNVFRSLIQIQKNIMKEDPLIRN--------DYEP- 293
Query: 333 SGTQVLPITWRHAIGFXXXXXXXXXXXXXLP---------TLADLTVDGIRPLRKLLGDV 383
Q+LPI WR+ + F + ++ D+ +D I +R+LLGDV
Sbjct: 294 ---QLLPICWRNKLNFNSYIKPVAGDEGRVEDEEFEENRFSIEDIEIDSIPAVRRLLGDV 350
Query: 384 GLDILLYGDDFYLDRILKHVTNELNDVYEKYREHNPEF---DGKVSLLGHSLGSVILFDI 440
DI Y + + I+K V E N VY +++ NP F G++ ++GHSLGS ++FDI
Sbjct: 351 MSDIPYYMSH-HKESIIKSVIREANRVYHLWKDCNPYFLENKGRIFIIGHSLGSTVVFDI 409
Query: 441 LSQQSKFPLN-----------FEVDNFFAIGSPIGVF------KLIQRTKIGES------ 477
LS Q F F+ + FF G P+G F +I R G S
Sbjct: 410 LSLQPTFVKEITIDDDESCFIFDTNGFFCFGGPVGFFLHLNQQSIIPRRGRGSSRYEINK 469
Query: 478 -------------DSSTRQQTPACNNFYNLFHPCDPISYRVEPLID 510
D R A ++FYN+++ DP++ R+ P +D
Sbjct: 470 NFINSDVPKSYTYDGYDRYGCLAVDSFYNIYNHLDPVAMRLNPTVD 515
>At1g31480 [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 869
Score = 90.1 bits (222), Expect = 9e-18
Identities = 99/396 (25%), Positives = 154/396 (38%), Gaps = 95/396 (23%)
Query: 74 LFEVDLEKFSMNPIYWDGPSYEIRRGIWFDDQNR----PLSHDLTKAIEELHQQ--WLSR 127
L+EVDL + P+YW+G + + RG WF + P+ +++ +E ++ W R
Sbjct: 162 LYEVDLVRRHCFPVYWNGDNRRVLRGHWFARKGGLDWLPIPETVSEQLEVAYRNKVWRRR 221
Query: 128 DKEKSKTTELRDIFRLPKDSKWKYVMFFEDDRT--AFLLPDIYGGHLQLTILRSSVAQLI 185
+ S R L S + +F +D T A+L D G S +
Sbjct: 222 SFQPSGLFAAR--IDLQGSSLGLHALFTGEDDTWEAWLNVDPSGF--------SGIVGYT 271
Query: 186 QLGASKLTKGYEEPSSLTERAKEIEGQVIEHAMGLGKISDMISWEFSDLVKFPNEENNSK 245
G KL +GY G S P +E +
Sbjct: 272 GNGI-KLRRGYA-----------------------GSYSPK-----------PTQEELRQ 296
Query: 246 QEEDMMKDEMSKDYDNGDSSEKSHYRPTNHLVLCVHGIGQNLGKKYQYVNFAHTVNLLRN 305
Q+E+ M D S+ P HLV VHGIGQ K + N V R
Sbjct: 297 QKEEEMDDYCSQV-------------PVRHLVFMVHGIGQ----KGEKSNLVDDVGNFRQ 339
Query: 306 NIKYLYKSNPSLQEFNSARKFPDYKTNSGTQVLPITWRHAIGFXXXXXXXXXXXXXLPTL 365
L + + + + ++ R +P WR + +
Sbjct: 340 ITAALAERHLTSHQLSTQRVL----------FIPCQWRKGLKLSGEAA-----------V 378
Query: 366 ADLTVDGIRPLRKLLGDVGLDILLYGDDFYLDRILKHVTNELNDVYEKYREHNPEFDGKV 425
T+DG+R R++L D+L Y Y I+ V+ +LN +Y K+ + NP++ GK+
Sbjct: 379 DKCTLDGVRRFREMLSATVHDVLYYMSPIYCQAIIDSVSKQLNRLYLKFLKRNPDYVGKI 438
Query: 426 SLLGHSLGSVILFDILSQQ----SKFPLNFEVDNFF 457
S+ GHSLGSV+ +DIL Q S FP++ FF
Sbjct: 439 SIYGHSLGSVLSYDILCHQHNLSSPFPMDSVYKKFF 474
Score = 80.1 bits (196), Expect = 9e-15
Identities = 56/206 (27%), Positives = 86/206 (41%), Gaps = 48/206 (23%)
Query: 449 LNFEVDNFFAIGSPIGVFKLIQRTKIGESDS------------STRQQTPACNNFYNLFH 496
L F+VD FFA+GSP+GVF ++ ++G ++ + ++ PAC +N+FH
Sbjct: 600 LEFKVDTFFAVGSPLGVFLALRNIRLGIGNTYLCKGKDYWEEENAIEEMPACRRMFNIFH 659
Query: 497 PCDPISYRVEPLIDKVTANYEAEWIPHATG--------YDFIAD---------------- 532
P DP++YRVEPL+ K IP+ G DF D
Sbjct: 660 PYDPVAYRVEPLVCKEYLPERPVIIPYHRGGKRLHIGLQDFREDFAARSQRIMNHFDSVR 719
Query: 533 ----TVKNLMSDKNLKEKELMTQ--------XXXXXXXXXXXXGRVDYSFQPNLLDVDVW 580
T+ S NL E E GR+D+ Q +
Sbjct: 720 TRVLTICQSKSADNLDEMEETDDEKDDRSYGSLMIERLTGTRDGRIDHMLQEKTFEHPYL 779
Query: 581 SAIKSHVSYFEDMDTAGFLLKEILKK 606
AI +H +Y+ D DTA F++K + ++
Sbjct: 780 QAIGAHTNYWRDQDTALFIIKHLYRE 805
>CE07393 [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 765
Score = 82.0 bits (201), Expect = 2e-15
Identities = 53/176 (30%), Positives = 86/176 (48%), Gaps = 29/176 (16%)
Query: 274 NHLVLCVHGIGQNLGKKYQYVNFAHTVNLLRNNIKYLYKSNPSLQEFNSARKFPDYKTNS 333
+HL+L VHGIGQ K Y+ NL+ N + S E + +P+ K S
Sbjct: 286 SHLILVVHGIGQ---KGYE--------NLIAQNANQVRDGVVSAME----KVYPEEK--S 328
Query: 334 GTQVLPITWRHAIGFXXXXXXXXXXXXXLPTLADLTVDGIRPLRKLLGDVGLDILLYGDD 393
LP+ WR A+ ++T+ + +R L +D++ Y
Sbjct: 329 RPMFLPVEWRSALKLDNGLTD------------NITIPKMSSMRASLNSTAMDVMYYQSP 376
Query: 394 FYLDRILKHVTNELNDVYEKYREHNPEFDGKVSLLGHSLGSVILFDILSQQSKFPL 449
+ I++ V ++LN Y+ ++ +NP+F+G VS+ GHSLGSVI +D+L+Q S L
Sbjct: 377 LFRTEIVRGVVSQLNRTYKLFKANNPQFNGHVSVFGHSLGSVICYDVLTQYSPLML 432
>Hs6005824 [IU] KOG2308 Phosphatidic acid-preferring phospholipase A1 contains
DDHD domain
Length = 1000
Score = 74.7 bits (182), Expect = 4e-13
Identities = 57/197 (28%), Positives = 84/197 (41%), Gaps = 30/197 (15%)
Query: 260 DNGDSSEKSHYRPTNHLVLCVHGIGQNLGKKYQYV-----NF-AHTVNLLRNNIKYLYKS 313
DN D +HLV VHGIG +++ + +F ++ LLR + K
Sbjct: 430 DNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLRTHFK----- 484
Query: 314 NPSLQEFNSARKFPDYKTNSGTQVLPITWRHAIGFXXXXXXXXXXXXXLPTLADLTVDGI 373
+ D K S + LP+ W ++G LP++
Sbjct: 485 ----------KSLDDGKV-SRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRF----- 528
Query: 374 RPLRKLLGDVGLDILLYGDDFYLDRILKHVTNELNDVYEKYREHNPEFDGKVSLLGHSLG 433
R + LDIL Y Y I++ V E+N ++ + NP+F G VS+ GHSLG
Sbjct: 529 ---RHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLG 585
Query: 434 SVILFDILSQQSKFPLN 450
S+ILFDILS Q L+
Sbjct: 586 SLILFDILSNQKDLNLS 602
Score = 60.8 bits (146), Expect = 6e-09
Identities = 31/78 (39%), Positives = 45/78 (56%), Gaps = 5/78 (6%)
Query: 449 LNFEVDNFFAIGSPIGVFKLIQRTKIGESDSSTRQQTPACNNFYNLFHPCDPISYRVEPL 508
L+FE + FFA+GSPI +F I+ G P C F+N++HP DP++YR+EP+
Sbjct: 779 LDFEPEIFFALGSPIAMFLTIR----GVDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPM 834
Query: 509 IDKVTANYEAEWIPHATG 526
I + +A IPH G
Sbjct: 835 I-VPDLDLKAVLIPHHKG 851
>Hs4758926 [IT] KOG3668 Phosphatidylinositol transfer protein
Length = 1244
Score = 57.8 bits (138), Expect = 5e-08
Identities = 49/199 (24%), Positives = 80/199 (39%), Gaps = 44/199 (22%)
Query: 449 LNFEVDNFFAIGSPIGVFKLIQRTKIGESDSSTRQQTPACNNFYNLFHPCDPISYRVEPL 508
L+F+V FF GSP+G+ +++T + +++ Q PAC YNLFH DP + R+EPL
Sbjct: 686 LDFKVSGFFLFGSPLGLVLALRKTVMPALEAA--QMRPACEQIYNLFHAADPCASRLEPL 743
Query: 509 IDKVTANYEAEWIPHATGYD-------FIADTVKNLMSDKNLKEKELMTQXXXXXXXXXX 561
+ +P + +ADT++ S L+E E++
Sbjct: 744 LAPKFQAIAPLTVPRYQKFPLGDGSSLLLADTLQT-HSSLFLEELEMLVPSTPTSTSGAF 802
Query: 562 XXG-------------------------------RVDYS-FQPNLLDV--DVWSAIKSHV 587
G R+DYS + P L V H
Sbjct: 803 WKGSELATDPPAQPAAPSTTSEVVKILERWWGTKRIDYSLYCPEALTAFPTVTLPHLFHA 862
Query: 588 SYFEDMDTAGFLLKEILKK 606
SY+E D F+L+++++K
Sbjct: 863 SYWESADVVAFILRQVIEK 881
>Hs20553175 [IT] KOG3668 Phosphatidylinositol transfer protein
Length = 1349
Score = 55.1 bits (131), Expect = 3e-07
Identities = 25/62 (40%), Positives = 38/62 (60%), Gaps = 2/62 (3%)
Query: 450 NFEVDNFFAIGSPIGVFKLIQRTKIGESDSSTRQQTPACNNFYNLFHPCDPISYRVEPLI 509
+FE+ + F G P+G+ +++T I D Q PAC YNLFHP DP + R+EPL+
Sbjct: 716 DFEITDLFLFGCPLGLVLALRKTVIPALD--VFQLRPACQQVYNLFHPADPSASRLEPLL 773
Query: 510 DK 511
++
Sbjct: 774 ER 775
>7292924 [IT] KOG3668 Phosphatidylinositol transfer protein
Length = 1250
Score = 53.1 bits (126), Expect = 1e-06
Identities = 26/61 (42%), Positives = 36/61 (58%), Gaps = 4/61 (6%)
Query: 449 LNFEVDNFFAIGSPIGVFKLIQRTKIGESDSSTRQQTPACNNFYNLFHPCDPISYRVEPL 508
L+FEV +FF GSP+ V ++ D+ P C+ YNLFHP DPI+ R+EPL
Sbjct: 730 LDFEVCDFFMFGSPLSVVLAARKLH----DAKAALPRPNCHQVYNLFHPTDPIASRLEPL 785
Query: 509 I 509
+
Sbjct: 786 L 786
>Hs13654296 [IT] KOG3668 Phosphatidylinositol transfer protein
Length = 974
Score = 51.2 bits (121), Expect = 5e-06
Identities = 24/61 (39%), Positives = 38/61 (61%), Gaps = 2/61 (3%)
Query: 450 NFEVDNFFAIGSPIGVFKLIQRTKIGESDSSTRQQTPACNNFYNLFHPCDPISYRVEPLI 509
+F+V +FF GSP+G+ ++RT + D Q PAC+ Y+ FH DP + R+EPL+
Sbjct: 391 DFDVSDFFLFGSPLGLVLAMRRTVLPGLDGF--QVRPACSQVYSFFHCADPSASRLEPLL 448
Query: 510 D 510
+
Sbjct: 449 E 449
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,639,045
Number of Sequences: 60738
Number of extensions: 1730971
Number of successful extensions: 5299
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 5231
Number of HSP's gapped (non-prelim): 39
length of query: 629
length of database: 30,389,216
effective HSP length: 113
effective length of query: 516
effective length of database: 23,525,822
effective search space: 12139324152
effective search space used: 12139324152
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)