ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2416 good U KOG1061 Intracellular trafficking, secretion, and vesicular transport Vesicle coat complex AP-1/AP-2/AP-4, beta subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2416 843133 845220 696
(696 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR005w [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 611 e-174
HsM4501973 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 301 3e-81
Hs22027653 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 301 3e-81
Hs22027651 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 301 3e-81
Hs4557469 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 292 1e-78
7293642 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 283 8e-76
At4g23460 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 276 1e-73
At4g11380 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 274 4e-73
CE24628 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 269 9e-72
SPBC2G2.06c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta... 254 2e-67
SPBC947.02 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 210 7e-54
YKL135c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 181 4e-45
Hs18596139 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 169 1e-41
At5g11490 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 160 6e-39
Hs5729742 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 160 8e-39
Hs4758760 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 101 3e-21
Hs4501975 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 100 1e-20
7290497 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 82 4e-15
SPAC23H3.06 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 80 1e-14
At3g55480_2 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 60 1e-08
>YJR005w [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 700
Score = 611 bits (1575), Expect = e-174
Identities = 329/701 (46%), Positives = 468/701 (65%), Gaps = 8/701 (1%)
Query: 1 MSESKIFYKYKAHEIRGELVSDSGKARGSS--KRKLCLRKIIANLIMGNYHEMAQLFVDV 58
MS+ K+F +YKA+EI +L K S+ +RK LRKIIANL++GNY EM+ LF ++
Sbjct: 1 MSDQKVFARYKANEIVTDLQHFGVKKFKSNITRRKNALRKIIANLVLGNYGEMSVLFSEL 60
Query: 59 LQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSI 118
L+ W E+DLE+KR+CH+Y + KP Q R ALP I+ D S E+L I++LRT+ +
Sbjct: 61 LKFWQIEDDLEVKRICHEYIRVIGALKPQQAREALPFIMDDFKSRDEKLQIMALRTLVLV 120
Query: 119 DEPEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDYG 178
E + F + L+ S + + AI++L+ +D++DH +VL L L D++
Sbjct: 121 PVKELSDQAFDCIISLVNHKSPPE-QVTRTAIYALLDLDEIDHERVLGLSSILHDIVKAQ 179
Query: 179 KEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTTAY 238
P ++VAA+ L+ IH N +M P ++ + F++LE+L ++NEW+ A + ++LTT+
Sbjct: 180 SSSPEVIVAALHTLYSIHEKNANMEPFRIPLELAFDMLELLPELNEWNKATVLEVLTTSV 239
Query: 239 LPKTHSEAHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYVDYIEERLVRKFSSSLTSLL 298
+P+ + + H +I+L++P L +N+ VVLN+LKFI+YL NYVD I+E L K S+S+ +LL
Sbjct: 240 VPQHYLDTHEMIELALPYLQQVNTYVVLNSLKFIMYLLNYVDVIKETLAEKLSNSVIALL 299
Query: 299 NKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEENT 358
+KPPE+QF SR+S L+ L+ + FFIEY+DP YIKDTKLE LYLLAN+E
Sbjct: 300 DKPPELQFLVLRNVILLLLSRESSLLRLDISYFFIEYNDPIYIKDTKLECLYLLANKETL 359
Query: 359 SQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPH-SARYSVDVLLELLEFGVDYIVQEV 417
+IL+EL+ ATDIDIQMS+KS+RAIGNLAVK S V VLL+LLEFGVDY+VQE+
Sbjct: 360 PRILEELEQYATDIDIQMSRKSVRAIGNLAVKLDEDSVHDCVAVLLDLLEFGVDYVVQEI 419
Query: 418 VSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRKYS 477
+S+ +N+LRKYPN F V L ++++ +Q+ ESK AMIWI+T +S+ + + + +FR +S
Sbjct: 420 ISVFRNILRKYPNNFKANVTELVKHTEVVQEPESKNAMIWIITQYSDVIPNYLELFRVFS 479
Query: 478 DNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWRL 537
N +E LEVQ +LNSA+KFF R+ +KETE+LC+ LL G + +NPDLRD MYWRL
Sbjct: 480 SNMFSETLEVQFSILNSAIKFFIRSPTKETEELCMDLLKGCIDHENNPDLRDKTLMYWRL 539
Query: 538 LSLAGNSS-EPLFNNDVVRDMIDGELPVIEINTKLDPIVREELELNIGSILSVYLKPVSQ 596
LSL S + ++ ++DGELP+IE+NTKLDP V EELELNIG+I+S+YLKPVS
Sbjct: 540 LSLTKTSRISNAITFESLKSVLDGELPLIEMNTKLDPTVLEELELNIGTIVSIYLKPVSH 599
Query: 597 VFRGVSPKKLPESPALNHEKXXXXXXXXXXXXXXTGSFHGSDTTRRSSSPIK--KMTDFD 654
+FR K LP+SP LN K + ++ S+ K M D+D
Sbjct: 600 IFRLNKTKLLPQSPILNPNKDLLPVVGNSFPPTGANRDRQNSESQSSTKSRKTAMMDDYD 659
Query: 655 RPAETVNQLKDKRKSSISLSATKLARKPSMLARKLSMRKPF 695
+PAE +NQLK KRKSS S + +KL+RKPS L RKLSM++PF
Sbjct: 660 KPAEKINQLKGKRKSS-SNNPSKLSRKPSTLLRKLSMKRPF 699
>HsM4501973 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 949
Score = 301 bits (770), Expect = 3e-81
Identities = 204/623 (32%), Positives = 341/623 (53%), Gaps = 37/623 (5%)
Query: 1 MSESKIFYKYKAHEI---RGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVD 57
M++SK F K EI + EL SD K+K ++K+IA++ +G +++ LF D
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDK-----KEKKKEAVKKVIASMTVGK--DVSALFPD 53
Query: 58 VLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITS 117
V+ ++N LE+K++ + Y S+PD MA+ ++D + + L++RT+
Sbjct: 54 VVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGC 112
Query: 118 IDEPEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDY 177
I + + + ++K + +RK A + K+ ++ +++E FL + D
Sbjct: 113 IRVDKITEYLCEPLRKCLKDEDPY---VRKTAAVCVAKLHDIN-AQLVEDQGFLDTLKDL 168
Query: 178 -GKEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTT 236
P ++ AV L EI S+P N L L LL L + EW + D L
Sbjct: 169 ISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLAN 228
Query: 237 AYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNA----LKFIIYLTNYVDYIEERLVRKFSS 292
Y+PK EA + + P+L + NS+VVL+A +KF+ L+ +DY L++K +
Sbjct: 229 -YMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGT-LLKKLAP 286
Query: 293 SLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLL 352
L +LL+ PE+Q+ R L H E FF++Y+DP Y+K KL+I+ L
Sbjct: 287 PLVTLLSAEPELQYVALRNINLIVQKRPEILKH-EMKVFFVKYNDPIYVKLEKLDIMIRL 345
Query: 353 ANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDY 412
A++ N +Q+L ELK AT++D+ +K++RAIG A+K SA V LL+L++ V+Y
Sbjct: 346 ASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNY 405
Query: 413 IVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGV 472
+VQE + ++K++ RKYPN+++ V+ L + DS+ + E++ AMIWIV ++ ++++ +
Sbjct: 406 VVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADEL 465
Query: 473 FRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAY 532
+ + F+ E +VQL LL + VK F + + ET++L ++LS AT+ +DNPDLRD Y
Sbjct: 466 LESFLEGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGY 524
Query: 533 MYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTKL-DPIVREELELNIGSILSVYL 591
+YWRLL S++P+ ++++ E P+I T L +P + +EL IG++ SVY
Sbjct: 525 IYWRLL-----STDPV----AAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYH 575
Query: 592 KPVSQVF---RGVSPKKLPESPA 611
KP S RGV K LP A
Sbjct: 576 KPPSAFVEGGRGVVHKSLPPRTA 598
>Hs22027653 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 942
Score = 301 bits (770), Expect = 3e-81
Identities = 204/623 (32%), Positives = 341/623 (53%), Gaps = 37/623 (5%)
Query: 1 MSESKIFYKYKAHEI---RGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVD 57
M++SK F K EI + EL SD K+K ++K+IA++ +G +++ LF D
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDK-----KEKKKEAVKKVIASMTVGK--DVSALFPD 53
Query: 58 VLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITS 117
V+ ++N LE+K++ + Y S+PD MA+ ++D + + L++RT+
Sbjct: 54 VVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGC 112
Query: 118 IDEPEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDY 177
I + + + ++K + +RK A + K+ ++ +++E FL + D
Sbjct: 113 IRVDKITEYLCEPLRKCLKDEDPY---VRKTAAVCVAKLHDIN-AQLVEDQGFLDTLKDL 168
Query: 178 -GKEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTT 236
P ++ AV L EI S+P N L L LL L + EW + D L
Sbjct: 169 ISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLAN 228
Query: 237 AYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNA----LKFIIYLTNYVDYIEERLVRKFSS 292
Y+PK EA + + P+L + NS+VVL+A +KF+ L+ +DY L++K +
Sbjct: 229 -YMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGT-LLKKLAP 286
Query: 293 SLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLL 352
L +LL+ PE+Q+ R L H E FF++Y+DP Y+K KL+I+ L
Sbjct: 287 PLVTLLSAEPELQYVALRNINLIVQKRPEILKH-EMKVFFVKYNDPIYVKLEKLDIMIRL 345
Query: 353 ANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDY 412
A++ N +Q+L ELK AT++D+ +K++RAIG A+K SA V LL+L++ V+Y
Sbjct: 346 ASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNY 405
Query: 413 IVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGV 472
+VQE + ++K++ RKYPN+++ V+ L + DS+ + E++ AMIWIV ++ ++++ +
Sbjct: 406 VVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADEL 465
Query: 473 FRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAY 532
+ + F+ E +VQL LL + VK F + + ET++L ++LS AT+ +DNPDLRD Y
Sbjct: 466 LESFLEGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGY 524
Query: 533 MYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTKL-DPIVREELELNIGSILSVYL 591
+YWRLL S++P+ ++++ E P+I T L +P + +EL IG++ SVY
Sbjct: 525 IYWRLL-----STDPV----AAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYH 575
Query: 592 KPVSQVF---RGVSPKKLPESPA 611
KP S RGV K LP A
Sbjct: 576 KPPSAFVEGGRGVVHKSLPPRTA 598
>Hs22027651 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 949
Score = 301 bits (770), Expect = 3e-81
Identities = 204/623 (32%), Positives = 341/623 (53%), Gaps = 37/623 (5%)
Query: 1 MSESKIFYKYKAHEI---RGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVD 57
M++SK F K EI + EL SD K+K ++K+IA++ +G +++ LF D
Sbjct: 1 MTDSKYFTTTKKGEIFELKAELNSDK-----KEKKKEAVKKVIASMTVGK--DVSALFPD 53
Query: 58 VLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITS 117
V+ ++N LE+K++ + Y S+PD MA+ ++D + + L++RT+
Sbjct: 54 VVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGC 112
Query: 118 IDEPEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDY 177
I + + + ++K + +RK A + K+ ++ +++E FL + D
Sbjct: 113 IRVDKITEYLCEPLRKCLKDEDPY---VRKTAAVCVAKLHDIN-AQLVEDQGFLDTLKDL 168
Query: 178 -GKEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTT 236
P ++ AV L EI S+P N L L LL L + EW + D L
Sbjct: 169 ISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLAN 228
Query: 237 AYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNA----LKFIIYLTNYVDYIEERLVRKFSS 292
Y+PK EA + + P+L + NS+VVL+A +KF+ L+ +DY L++K +
Sbjct: 229 -YMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGT-LLKKLAP 286
Query: 293 SLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLL 352
L +LL+ PE+Q+ R L H E FF++Y+DP Y+K KL+I+ L
Sbjct: 287 PLVTLLSAEPELQYVALRNINLIVQKRPEILKH-EMKVFFVKYNDPIYVKLEKLDIMIRL 345
Query: 353 ANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDY 412
A++ N +Q+L ELK AT++D+ +K++RAIG A+K SA V LL+L++ V+Y
Sbjct: 346 ASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNY 405
Query: 413 IVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGV 472
+VQE + ++K++ RKYPN+++ V+ L + DS+ + E++ AMIWIV ++ ++++ +
Sbjct: 406 VVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADEL 465
Query: 473 FRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAY 532
+ + F+ E +VQL LL + VK F + + ET++L ++LS AT+ +DNPDLRD Y
Sbjct: 466 LESFLEGFHDESTQVQLQLLTAIVKLFLK-KPTETQELVQQVLSLATQDSDNPDLRDRGY 524
Query: 533 MYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTKL-DPIVREELELNIGSILSVYL 591
+YWRLL S++P+ ++++ E P+I T L +P + +EL IG++ SVY
Sbjct: 525 IYWRLL-----STDPV----AAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYH 575
Query: 592 KPVSQVF---RGVSPKKLPESPA 611
KP S RGV K LP A
Sbjct: 576 KPPSAFVEGGRGVVHKSLPPRTA 598
>Hs4557469 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 937
Score = 292 bits (747), Expect = 1e-78
Identities = 196/616 (31%), Positives = 339/616 (54%), Gaps = 31/616 (5%)
Query: 1 MSESKIFYKYKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQ 60
M++SK F K EI EL ++ + KRK ++K+IA + +G +++ LF DV+
Sbjct: 1 MTDSKYFTTNKKGEIF-ELKAELNNEK-KEKRKEAVKKVIAAMTVGK--DVSSLFPDVVN 56
Query: 61 IWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDE 120
++N LE+K++ + Y S+PD MA+ ++D + + L++RT+ I
Sbjct: 57 CMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRV 115
Query: 121 PEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDY-GK 179
+ + + ++K + +RK A + K+ ++ +++E FL + D
Sbjct: 116 DKITEYLCEPLRKCLKDEDPY---VRKTAAVCVAKLHDIN-AQMVEDQGFLDSLRDLIAD 171
Query: 180 EEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTTAYL 239
P ++ AV L EI S+P+ N L L LL L + EW + D L+ Y
Sbjct: 172 SNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSN-YN 230
Query: 240 PKTHSEAHHLIDLSVPKLHNLNSSVVLNA----LKFIIYLTNYVDYIEERLVRKFSSSLT 295
PK EA + + P+L + NS+VVL+A +KF+ L DY L++K + L
Sbjct: 231 PKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYN-MLLKKLAPPLV 289
Query: 296 SLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANE 355
+LL+ PE+Q+ R ++ E FF++Y+DP Y+K KL+I+ LA++
Sbjct: 290 TLLSGEPEVQYVALRNINLIVQKRPE-ILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQ 348
Query: 356 ENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQ 415
N +Q+L ELK AT++D+ +K++RAIG A+K SA V LL+L++ V+Y+VQ
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQ 408
Query: 416 EVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRK 475
E + +++++ RKYPN+++ ++ L + DS+ + +++ AMIWIV ++ ++++ +
Sbjct: 409 EAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLES 468
Query: 476 YSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYW 535
+ + F+ E +VQL LL + VK F + S ET++L ++LS AT+ +DNPDLRD Y+YW
Sbjct: 469 FLEGFHDESTQVQLTLLTAIVKLFLKKPS-ETQELVQQVLSLATQDSDNPDLRDRGYIYW 527
Query: 536 RLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTKL-DPIVREELELNIGSILSVYLKPV 594
RLL S++P+ ++++ E P+I T L +P + +EL +IGS+ SVY KP
Sbjct: 528 RLL-----STDPV----TAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPP 578
Query: 595 S---QVFRGVSPKKLP 607
+ + G+ K LP
Sbjct: 579 NAFVEGSHGIHRKHLP 594
>7293642 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 921
Score = 283 bits (723), Expect = 8e-76
Identities = 185/610 (30%), Positives = 330/610 (53%), Gaps = 35/610 (5%)
Query: 1 MSESKIFYKYKAHEI---RGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVD 57
M++SK F K EI + EL +D K+K ++K+IA++ +G +++ LF D
Sbjct: 1 MTDSKYFTTTKKGEIFELKSELNNDK-----KEKKKEAVKKVIASMTVGK--DVSALFPD 53
Query: 58 VLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITS 117
V+ ++N LE+K++ + Y S+PD MA+ ++D ++ + L++RT+
Sbjct: 54 VVNCMQTDN-LELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGC 112
Query: 118 IDEPEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYF--LMDML 175
I + + + ++K + +RK A + K+ + T V + + L D+L
Sbjct: 113 IRVDKITEYLCEPLRKCLKDEDPY---VRKTAAVCVAKLYDISATMVEDQGFLDQLKDLL 169
Query: 176 DYGKEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFN-LLEVLGKINEWDIAILFDIL 234
P ++ AV L EI+ ++ PL ++ N LL L + EW + D L
Sbjct: 170 S--DSNPMVVANAVAALSEINEASQSGQPLVEMNSVTINKLLTALNECTEWGQVFILDSL 227
Query: 235 TTAYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYVDYIEE---RLVRKFS 291
Y PK EA + + P+L + N++VVL+A+K ++ L + + L +K +
Sbjct: 228 AN-YSPKDEREAQSICERITPRLAHANAAVVLSAVKVLMKLLEMLSSDSDFCATLTKKLA 286
Query: 292 SSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYL 351
L +LL+ PE+Q+ R L H E FF++Y+DP Y+K KL+I+
Sbjct: 287 PPLVTLLSSEPEVQYVALRNINLIVQKRPDILKH-EMKVFFVKYNDPIYVKLEKLDIMIR 345
Query: 352 LANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVD 411
LAN+ N +Q+L ELK AT++D+ +K++RAIG A+K SA V LL+L++ V+
Sbjct: 346 LANQSNIAQVLSELKEYATEVDVDFVRKAVRAIGRCAIKVEPSAERCVSTLLDLIQTKVN 405
Query: 412 YIVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIG 471
Y+VQE + ++K++ RKYPN+++ ++ L + D++ + E++ +M+WI+ ++ ++++
Sbjct: 406 YVVQEAIVVIKDIFRKYPNKYESIISTLCENLDTLDEPEARASMVWIIGEYAERIDNADE 465
Query: 472 VFRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNA 531
+ + + F E +VQL LL + VK F + S +T++L +LS AT+ +DNPDLRD
Sbjct: 466 LLDSFLEGFQDENAQVQLQLLTAVVKLFLKRPS-DTQELVQHVLSLATQDSDNPDLRDRG 524
Query: 532 YMYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTK-LDPIVREELELNIGSILSVY 590
++YWRLL S++P ++++ + P+I T L+P + +EL +I S+ SVY
Sbjct: 525 FIYWRLL-----STDPA----AAKEVVLADKPLISEETDLLEPTLLDELICHISSLASVY 575
Query: 591 LKPVSQVFRG 600
KP + G
Sbjct: 576 HKPPTAFVEG 585
>At4g23460 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 893
Score = 276 bits (705), Expect = 1e-73
Identities = 179/591 (30%), Positives = 318/591 (53%), Gaps = 25/591 (4%)
Query: 9 KYKAHEIRGEL--VSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQIWNSEN 66
KY + +GE+ + + ++ KRK ++K+IA + +G +++ LF DV+ +EN
Sbjct: 7 KYFSTTKKGEIPELKEELNSQYKDKRKDAVKKVIAAMTVGK--DVSSLFTDVVNCMQTEN 64
Query: 67 DLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDEPEYIQE 126
LE+K++ + Y S+PD +A+ ++D + + L++RT+ I + +
Sbjct: 65 -LELKKLVYLYLINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEY 123
Query: 127 GFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDY-GKEEPTIL 185
++K + +RK A + K+ ++ +++E FL + D P ++
Sbjct: 124 LCDPLQKCLKDDDPY---VRKTAAICVAKLFDIN-AELVEDRGFLEALKDLISDNNPMVV 179
Query: 186 VAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTTAYLPKTHSE 245
AV L EI N ++ I LL L + EW + D L+ Y E
Sbjct: 180 ANAVAALAEIQ-ENSTSPIFEINSTILTKLLTALNECTEWGQVFILDALSR-YKASDPRE 237
Query: 246 AHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYVDYIE--ERLVRKFSSSLTSLLNKPPE 303
A ++++ P+L + N +VVL+A+K I+ + + L +K + L +LL+ PE
Sbjct: 238 AENIVERVTPRLQHANCAVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPE 297
Query: 304 IQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEENTSQILD 363
IQ+ R + L H E FF +Y+DP Y+K KLEI+ LA++ N Q+L
Sbjct: 298 IQYVALRNINLIVQKRPTILAH-EIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVLL 356
Query: 364 ELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKN 423
E K AT++D+ +K++RAIG A+K +A + VLLEL++ V+Y+VQE + ++K+
Sbjct: 357 EFKEYATEVDVDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIKD 416
Query: 424 VLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRKYSDNFNTE 483
+ R+YPN ++ ++ L + D++ + E+K +MIWI+ ++ ++++ + + +NF E
Sbjct: 417 IFRRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAERIDNADELLESFLENFPEE 476
Query: 484 GLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWRLLSLAGN 543
+VQL LL + VK F + ++ +Q+ +L+ AT DNPDLRD AY+YWRLL
Sbjct: 477 PAQVQLQLLTATVKLFLKKPTEGPQQMIQVVLNNATVETDNPDLRDRAYIYWRLL----- 531
Query: 544 SSEPLFNNDVVRDMIDGELPVI-EINTKLDPIVREELELNIGSILSVYLKP 593
S++P + +D++ E PVI + + +LDP + +EL NI ++ SVY KP
Sbjct: 532 STDP----EAAKDVVLAEKPVITDDSNQLDPSLLDELLANISTLSSVYHKP 578
>At4g11380 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 894
Score = 274 bits (700), Expect = 4e-73
Identities = 178/591 (30%), Positives = 317/591 (53%), Gaps = 25/591 (4%)
Query: 9 KYKAHEIRGEL--VSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQIWNSEN 66
KY + +GE+ + + ++ KRK ++K+IA + +G +++ LF DV+ +EN
Sbjct: 7 KYFSTTKKGEIPELKEELNSQYKDKRKDAVKKVIAAMTVGK--DVSSLFTDVVNCMQTEN 64
Query: 67 DLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDEPEYIQE 126
LE+K++ + Y S+PD +A+ ++D + + L++RT+ I + +
Sbjct: 65 -LELKKLVYLYLINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEY 123
Query: 127 GFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDY-GKEEPTIL 185
++K + +RK A + K+ ++ +++E FL + D P ++
Sbjct: 124 LCDPLQKCLKDDDPY---VRKTAAICVAKLFDIN-AELVEDRGFLEALKDLISDNNPMVV 179
Query: 186 VAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTTAYLPKTHSE 245
AV L EI N ++ LL L + EW + D L+ Y E
Sbjct: 180 ANAVAALAEIQ-ENSSSPIFEINSTTLTKLLTALNECTEWGQVFILDALSK-YKAADPRE 237
Query: 246 AHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYVDYIE--ERLVRKFSSSLTSLLNKPPE 303
A ++++ P+L + N +VVL+A+K I+ + + L +K + L +LL+ PE
Sbjct: 238 AENIVERVTPRLQHANCAVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPE 297
Query: 304 IQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEENTSQILD 363
IQ+ R + L H E FF +Y+DP Y+K KLEI+ LA++ N Q+L
Sbjct: 298 IQYVALRNINLIVQKRPTILAH-EIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVLL 356
Query: 364 ELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKN 423
E K AT++D+ +K++RAIG A+K +A + VLLEL++ V+Y+VQE + ++K+
Sbjct: 357 EFKEYATEVDVDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIKD 416
Query: 424 VLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRKYSDNFNTE 483
+ R+YPN ++ ++ L + D++ + E+K +MIWI+ ++ ++++ + + +NF E
Sbjct: 417 IFRRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAERIDNADELLESFLENFPEE 476
Query: 484 GLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWRLLSLAGN 543
+VQL LL + VK F + ++ +Q+ +L+ AT DNPDLRD AY+YWRLL
Sbjct: 477 PAQVQLQLLTATVKLFLKKPTEGPQQMIQVVLNNATVETDNPDLRDRAYIYWRLL----- 531
Query: 544 SSEPLFNNDVVRDMIDGELPVI-EINTKLDPIVREELELNIGSILSVYLKP 593
S++P + +D++ E PVI + + +LDP + +EL NI ++ SVY KP
Sbjct: 532 STDP----EAAKDVVLAEKPVISDDSNQLDPSLLDELLTNISTLSSVYHKP 578
>CE24628 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 827
Score = 269 bits (688), Expect = 9e-72
Identities = 186/618 (30%), Positives = 332/618 (53%), Gaps = 44/618 (7%)
Query: 1 MSESKIFYKYKAHEI---RGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVD 57
M++SK F K EI + EL SD K+K ++K+IA++ +G +++ LF D
Sbjct: 1 MTDSKYFTTTKKGEIFELKNELNSDK-----KEKKKEAVKKVIASMTVGK--DVSALFPD 53
Query: 58 VLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITS 117
V+ ++N +E+K++ + Y S+PD MA+ ++D + + L++RT+
Sbjct: 54 VVNCMQTDN-VELKKLVYLYLMNYAKSQPDLAIMAVNTFVKDCEDPNPLIRALAVRTMGC 112
Query: 118 IDEPEYIQEGFQHVKKLIMTTSKISIP-LRKAAIHSLIKMDQLDHTKVLELYY--FLMDM 174
I +++ +++ + K P +RK A + K+ ++ V E + L D+
Sbjct: 113 IR----VEKITEYLCDPLRRCMKDEDPYVRKTAAVCVAKLHDMNPALVKEQGFVELLNDL 168
Query: 175 LDYGKEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDIL 234
L P ++ AV L E+ N +++ + LL L + EW + D L
Sbjct: 169 LS--DANPMVVANAVAALTEM---NEQQTVIEVNSQMVNKLLTALNECTEWGQVFILDAL 223
Query: 235 TTAYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYV----DYIEERLVRKF 290
Y P+ E ++ + P+L + N++VVL+ +K ++ L + + D+I + L +K
Sbjct: 224 A-GYTPRDERETQNICERISPRLAHANAAVVLSTVKVLMKLIDMMPADSDFITQ-LTKKL 281
Query: 291 SSSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILY 350
+ + +LL+ PEIQ+ R ++ E FF++Y+DP Y+K KL+I+
Sbjct: 282 APPMVTLLSAEPEIQYVALRNINLIVQKRPD-ILKQEMKVFFVKYNDPIYVKMEKLDIMI 340
Query: 351 LLANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGV 410
LA + N +Q+L ELK AT++D+ +KS+RAIG A+K S+ V LLEL++ V
Sbjct: 341 RLAQQNNIAQVLSELKEYATEVDVDFVRKSVRAIGRCAIKVEASSERCVQTLLELIQTKV 400
Query: 411 DYIVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPI 470
+Y+VQE V ++K++ RKYPN+++ ++ L + D++ + E++ +MIWI+ ++ ++++
Sbjct: 401 NYVVQEAVVVIKDIFRKYPNRYESIISALCENLDTLDEPEARASMIWIIGEYAERIDNAD 460
Query: 471 GVFRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDN 530
+ + + F+ E +VQL LL + VK F + + + L ++LS AT+ +DNPDLRD
Sbjct: 461 ELLESFVEGFHDENTQVQLQLLTAVVKLFLK-RPGVAQALVQRVLSLATQDSDNPDLRDR 519
Query: 531 AYMYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTK-LDPIVREELELNIGSILSV 589
++YWRLL S++P +VV E P+I T L+P + E+L +IG++ SV
Sbjct: 520 GFIYWRLL-----SADPAAAKNVVLT----EKPLISEETDLLEPSLLEQLVCHIGTLASV 570
Query: 590 YLKPVSQVFRGVSPKKLP 607
Y KP S + P K P
Sbjct: 571 YHKPPSAF---IDPAKAP 585
>SPBC2G2.06c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 677
Score = 254 bits (650), Expect = 2e-67
Identities = 187/678 (27%), Positives = 333/678 (48%), Gaps = 35/678 (5%)
Query: 1 MSESKIFYKYKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQ 60
MS S + A ++ SD+ K + ++KR L+K IA + G ++M+ LF V+
Sbjct: 1 MSSSSSHFSSTAADLLAVFSSDN-KDKSANKRISALKKAIAGISYG--YDMSSLFPSVIS 57
Query: 61 IWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDE 120
S N+LE+K++C+ Y KP + + A+ +IL D+ S++ + L+LRT+TS++
Sbjct: 58 SMES-NNLELKKLCYLYLKIYASVKPTEAKRAVKLILNDIYSSNPMIRSLALRTLTSVNI 116
Query: 121 PEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDYGKE 180
+ + +L+ T +RK A + K+ D K++E + + + +
Sbjct: 117 KNFWVAAMDPIVRLLDDTDPY---VRKTAAIGIAKLYSYDK-KMVESSGLIDHLKEMLSD 172
Query: 181 EPTILVA-AVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTTAYL 239
E +++VA ++ L I S+ L ++ I L++ L +EW + D L Y+
Sbjct: 173 ESSVVVANSLAALMNIVNSSTGFK-LTFSREISNKLVKSLTDCSEWLQVAILDALIF-YV 230
Query: 240 PKTHSEAHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYV---DYIEERLVRKFSSSLTS 296
P+ EA + P L + N++V + A+K I+YLTNY+ + ++E ++ +T
Sbjct: 231 PQKPGEAESFAERISPWLQHGNAAVCMGAVKVILYLTNYMKDDNRVKEYFMKTQPPLVTL 290
Query: 297 LLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEE 356
L K Q+ + + + F+ + DP Y+K KL+IL +A+
Sbjct: 291 LARKSSATQYVILRNIQIILEQCPEMFAN-DIHFFYCNFDDPIYVKLEKLDILTKIADIH 349
Query: 357 NTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQE 416
N QIL E A++ID+++ +KS++ IG LA+K +D L+EL+ V Y++QE
Sbjct: 350 NLDQILPEFVEYASEIDVELVRKSVKCIGYLAIKIEERKNDCIDSLIELMNTKVTYVIQE 409
Query: 417 VVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRKY 476
V +++++LRKYP + +VP+L + DS+ + ++K A+IWI+ ++ ++ED I + Y
Sbjct: 410 AVIVIRDILRKYPGSYKSLVPILYENLDSLDEPDAKSAVIWILGQYAEEIEDSITLLNDY 469
Query: 477 SDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWR 536
F E LE+QL LL + +K F + + + + L E+ND PDLRD +Y R
Sbjct: 470 LKGFFDEPLEIQLTLLTAVIKVFLKKPTAAADMVTNVLQWCTDEVND-PDLRDRGIIYSR 528
Query: 537 LLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTKL-DPIVREELELNIGSILSVYLKPVS 595
+LS N ++ + +I +P + + T + DP E+L LNI ++ S+Y KP +
Sbjct: 529 MLSA---------NPELAKKVILANMPPVNVGTGMYDPDTTEQLMLNISTLSSIYHKPPN 579
Query: 596 QVFRGVSPKKLPESPAL---NHEKXXXXXXXXXXXXXXTGSFHGSDTTRRSSSPIKKMTD 652
+ +G SP L + FH TRR M
Sbjct: 580 RFVKGAQVAYCEPSPVLRLRTRDSNPSNTDSRESNHKKYNHFHQKSQTRR------VMEQ 633
Query: 653 FDRPAETVNQLKDKRKSS 670
+DR + + D+ S+
Sbjct: 634 YDRNSWNPSPFSDESNSN 651
>SPBC947.02 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 683
Score = 210 bits (534), Expect = 7e-54
Identities = 157/601 (26%), Positives = 288/601 (47%), Gaps = 23/601 (3%)
Query: 2 SESKIFYKYKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQI 61
S K F K + E++ LVS R + +++ IA + +G +++ LF DVL+
Sbjct: 9 SRFKAFKKSETSELQKGLVSQYAYERIDA-----VKRTIAAMTVGK--DVSSLFPDVLKN 61
Query: 62 WNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDEP 121
+ D+ +K++ + Y + PD +A+ ++D + L L++RT+ I
Sbjct: 62 L-ATRDITLKKLVYLYLINYAKTHPDLCILAVNTFVKDSEEYNPTLRALAIRTMGCIRVN 120
Query: 122 EYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDYGKEE 181
+ I ++K + +RKAA ++KM LD +
Sbjct: 121 KIIGYLADPLRKALKDEHPY---VRKAAAVCVVKMYDLDREYCASNGFIEQLQALVSDPN 177
Query: 182 PTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILTTAYLPK 241
P ++ AV L EIH +P+ + + L+ L + NEW + + L +
Sbjct: 178 PVVVANAVRSLAEIHDQDPEKGYFNVVYTMTDRLMVALSECNEWGRITILNSLAR-FRTS 236
Query: 242 THSEAHHLIDLSVPKLHNLNSSVVLNALKFI-IYLTNYVDYIEERLVRKFSSSLTSLLNK 300
EA ++ + VP+ + NS VVL+A+K I +++ + + L +K + L +LL+
Sbjct: 237 DIKEAEYVCERVVPQFQHANSGVVLSAVKVIMVHIPLFSSDFTDFLYKKMAPPLLTLLST 296
Query: 301 PPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEENTSQ 360
EIQ+ R S + ++ FF +Y+DP YIK KL+I+ +LA +EN ++
Sbjct: 297 DSEIQYVALRNINLILQKRPS-IFDVKTRVFFCKYNDPLYIKMEKLKIITMLACDENINE 355
Query: 361 ILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSM 420
+ EL+ ++++++ K++I+ +G++A+K P + + LE+ E + Y+VQEV +
Sbjct: 356 TISELRAYVSEVELEFVKQTIKCLGDVALKVPSVINDCISIFLEIYELNISYMVQEVTVV 415
Query: 421 LKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRKYSDNF 480
++ VLRKYP + D ++P L + + + D ++ +M WI+ S+ + + +
Sbjct: 416 METVLRKYPQKIDLLLPYLSRVIEELGDPRARSSMAWILGEFSHVIPTSSKLLSEMISTM 475
Query: 481 NTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWRLLSL 540
E L++QL LL + VK E+L K+L+ A + N DLRD A+ Y RLL+
Sbjct: 476 ADEDLQIQLALLTAVVKLSLMNGKGNDEELVQKVLNYAINQSSNQDLRDRAFAYQRLLTP 535
Query: 541 AGNSSEPLFNNDVVRDMIDGELPVIEINTKLDPIVREELELNIGSILSVYLK-PVSQVFR 599
N + ++ E P + N L + + L I ++ SVY K P S + +
Sbjct: 536 E--------NVRKAQKIVCCEKPSVSYNNNLPEALLDALLCEITTLASVYHKLPESFIGQ 587
Query: 600 G 600
G
Sbjct: 588 G 588
>YKL135c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 726
Score = 181 bits (458), Expect = 4e-45
Identities = 172/618 (27%), Positives = 288/618 (45%), Gaps = 55/618 (8%)
Query: 5 KIFYKYKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQIWNS 64
KI K + E+R LVS + R K ++K I + +G +++ LF DVL+ +
Sbjct: 21 KISGKGELSELRTGLVSQYPQTR-----KDAIKKTIQQMTLGK--DVSSLFPDVLKNI-A 72
Query: 65 ENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDEP--- 121
D+E K++ + Y + P+ +A+ + D + + +++RT++ I
Sbjct: 73 TIDVEQKKLVYLYVMNYAETHPELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKIL 132
Query: 122 EYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYF--LMDMLDYGK 179
EYI+ + T + +RK A+ + K+ QL+ +EL L++ LD
Sbjct: 133 EYIETPLRR------TLHDDNAYVRKTAVICVAKLFQLNKDLCVELGVVEDLVNALD--D 184
Query: 180 EEPTILVAAVTVLHEIHVSNPDMNPLQLT---QNICFNLLEVLGKINEWDIAILFDILTT 236
P ++ A L EIH N DM+ + L+ Q+ L L + EW I+ L+
Sbjct: 185 SNPLVIANATAALIEIH--NMDMDAVDLSSLIQSHVSQFLLALNECTEWARIIILGTLSE 242
Query: 237 AYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNALKFIIYLTNYVDYIEERLVRK-FSSSLT 295
Y K EA +ID L ++N +VVL +K I+ ++Y L+ K SS+
Sbjct: 243 -YSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKVIVRNLPQIEYSSNSLIMKRLSSAFV 301
Query: 296 SLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANE 355
SL++ PPE+Q+ + L+ E F+++++DP Y+K K++IL L +
Sbjct: 302 SLMSTPPEMQYVALKNIRIIL-EKYPELLTKELRIFYVKFNDPLYVKLEKIDILVRLVDP 360
Query: 356 ENTSQ---ILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYS--VDVLLELLEFGV 410
N Q +L ELK A + + + ++I+A+ L +KY + S +D+LLELLE
Sbjct: 361 SNLKQCTLLLTELKEYAMEYEPEFVSRAIQALSQLGIKYAQESFVSKVLDILLELLE-RQ 419
Query: 411 DYIVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSD------SIQDSESKCAMIWIVTNHSN 464
D I + L ++LR P + ++ +Q +KC +W++ H N
Sbjct: 420 DTIKDDCCISLCDLLRHCPGNDKMAKQVCAVFNTWSNPEVLLQSDIAKCNYVWLLGQHPN 479
Query: 465 QLEDPIGVFRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDN 524
D + +NF E Q+ LL + V R + T + +L AT+
Sbjct: 480 NFSDLESKINIFIENFVQEEALTQMSLLMTIV----RLHATLTGSMLQSVLELATQQTHE 535
Query: 525 PDLRDNAYMYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINT--KLDPIVREELELN 582
D+RD A MYWR LS+ N S +V D+ +LP+I NT K P V E+L +
Sbjct: 536 LDVRDMAMMYWRCLSMPNNES-------LVNDLCQNKLPMIS-NTLEKFSPEVLEKLLME 587
Query: 583 IGSILSVYLKPVSQVFRG 600
+G+I S+Y KP S +G
Sbjct: 588 LGTISSIYFKPDSNRRKG 605
>Hs18596139 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 863
Score = 169 bits (428), Expect = 1e-41
Identities = 158/620 (25%), Positives = 291/620 (46%), Gaps = 104/620 (16%)
Query: 1 MSESKIFY---KYKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVD 57
M++SK F K + E++ EL ++ KRK ++K+IA + +G +++ +F D
Sbjct: 1 MTDSKYFTTNKKAEIFELKAELSNEK-----KEKRKEAVKKVIAVITVGK--DVSSVFPD 53
Query: 58 VLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITS 117
++ ++N L++K++ + Y S+PD +A+ ++D + + L++RT+
Sbjct: 54 IVNCMQTDN-LKLKKLVYLYLMNYANSQPDMAIIAVNSFVKDCEDPNLLIRALAVRTMGC 112
Query: 118 IDEPEYIQEGFQHVKKLIMTTSKISIP-LRKAAIHSLIKMDQLDHTKVLELYYFLMDMLD 176
I ++ + +++ + ++ + P +RK A + K+ ++ +++E FL +
Sbjct: 113 I----WVDKITEYLSEPLLKCLEDEDPYVRKTAAVCVAKLHDIN-AQMVEDQGFLDSLWG 167
Query: 177 Y-GKEEPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILT 235
P ++ AV L EI S+P+ N L L L L K E F T
Sbjct: 168 LIADSNPMVVANAVAALSEISESHPNSNLLNLNTQYINKLRTALNKCTE---GARFSCWT 224
Query: 236 TAYLPKTHSEAHHLIDLSVPKLHNLNSSVVLNA----LKFIIYLTNYVDYIEERLVRKFS 291
+ +I L + NS+VVL+A +KF+ L DY L++K +
Sbjct: 225 ACLITTLK-----MIGRLRASLSHANSAVVLSAVKVLMKFLELLPKDSDYYN-MLLKKLA 278
Query: 292 SSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYL 351
L +L++ E+ + R ++ E FF++Y+DP Y+K KL+I
Sbjct: 279 PPLVTLMSGESEVHYVSLRNINLIVQKRPE-ILKQEIKVFFVKYNDPIYVKLEKLDIRIH 337
Query: 352 LANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVD 411
LA++ N +Q+L ELK AT++++ +K++ A G A+K SA + V LL+L++ V+
Sbjct: 338 LASQANIAQVLAELKEYATEVNVDFVRKAVWATGRCAIKVEQSAEHCVSTLLDLIKTKVN 397
Query: 412 YIVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPIG 471
Y+VQEV+ +++++
Sbjct: 398 YVVQEVIVVIRDI----------------------------------------------- 410
Query: 472 VFRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDLRDNA 531
FRKYS+ + + ++ +V ++ +T++L ++L+ AT+ +DNPDLR+
Sbjct: 411 -FRKYSNKYES-------IIATLSVS----QETTKTQELVQQMLTLATQDSDNPDLRERG 458
Query: 532 YMYWRLLSLAGNSSEPLFNNDVVRDMIDGELPVIEINTK-LDPIVREELELNIGSILSVY 590
Y YW L S++P+ +VV E P+I T+ ++P EEL +IGS+ SVY
Sbjct: 459 YTYWAPL-----SADPVMAKEVVL----SEKPLISQETEPIEPTALEELICHIGSLASVY 509
Query: 591 LKPVS---QVFRGVSPKKLP 607
KP S + G+ K LP
Sbjct: 510 RKPSSAFVEGSHGIHRKHLP 529
>At5g11490 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 841
Score = 160 bits (405), Expect = 6e-39
Identities = 123/519 (23%), Positives = 259/519 (49%), Gaps = 21/519 (4%)
Query: 30 SKRKLCLRKIIANLIMGNYHEMAQLFVDVLQIWNSENDLEIKRMCHQYFCTLTPSKPDQL 89
SKR L +K+I+ + +G +++ +F +++ ++ +D+ +K+MC+ Y PD
Sbjct: 43 SKRDL-YKKVISYMTIGI--DVSSVFGEMVMC-SATSDIVLKKMCYLYVGNYAKGNPDLS 98
Query: 90 RMALPIILQDLLSNSEELCILSLRTITSIDEPEYIQEGFQHVKKLIMTTSKISIPLRKAA 149
+ + + +D + L+LR++ S+ P ++ V L + +R A
Sbjct: 99 LLTINFLQRDCKDEDPMIRGLALRSLCSLRVPNLVE---YLVGPLGSGLKDNNSYVRTIA 155
Query: 150 IHSLIKMDQLDHTKVLELYY-FLMDMLDYGKEEPTILVAAVTVLHEI---HVSNPDMNPL 205
+ ++K+ + + ++ + + L + ++ ++ L EI S+ +
Sbjct: 156 VTGVLKLYHISPSTCIDADFPATLKSLMLHDSDAQVVANCLSALQEIWSLEASHSEEACR 215
Query: 206 Q----LTQNICFNLLEVLGKINEWDIAILFDILTTAYLPKTHSEAHHLIDLSVPKLHNLN 261
+ L++ + + L + + NEW ++ + L Y+P ++ +++L +L + N
Sbjct: 216 EKESLLSKPVIYYFLNRIKEFNEWAQCLILE-LAVKYVPSDSNDIFDIMNLLEDRLQHAN 274
Query: 262 SSVVLNALKFIIYLTNYVDYIEERLVRKFSSSLTSLLNKPPEIQFXXXXXXXXXXXSRDS 321
+VVL +K + LT + + +++ + S L +L++ Q R
Sbjct: 275 GAVVLATVKVFLQLTLSMTDVHQQVYERIKSPLLTLVSSGSPEQSYAILSHLHLLVVRAP 334
Query: 322 PLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEENTSQILDELKGQATDIDIQMSKKSI 381
+ + +F+ +Y++P+Y+K KLE+L +ANE NT +I+ EL A ++DI ++++SI
Sbjct: 335 FIFAADYKHFYCQYNEPSYVKKLKLEMLTAVANESNTYEIVTELCEYAANVDIAIARESI 394
Query: 382 RAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKNVLRKYPN-QFDFVVPLLP 440
RA+G +A++ + VD LL+ LE DY+ E + ++K++LRKYP D + +
Sbjct: 395 RAVGKIALQ-QYDVNAIVDRLLQFLEMEKDYVTAETLVLVKDLLRKYPQWSHDCISVVGG 453
Query: 441 QYSDSIQDSESKCAMIWIVTNHSNQLEDPIGVFRKYSDNFNTE-GLEVQLLLLNSAVKFF 499
S +IQ+ ++K A+IW++ ++ + D V +N+ E EV+L LL +A+K F
Sbjct: 454 ISSKNIQEPKAKAALIWMLGEYAQDMSDAPYVLENLIENWEEEHSAEVRLHLLTAAMKCF 513
Query: 500 CRAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWRLL 538
+ + + L L +G + + D+ D A Y+R+L
Sbjct: 514 FKRAPETQKALGTALAAGIADFHQ--DVHDRALFYYRVL 550
>Hs5729742 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 739
Score = 160 bits (404), Expect = 8e-39
Identities = 135/515 (26%), Positives = 250/515 (48%), Gaps = 27/515 (5%)
Query: 33 KLCLRKIIANLI--MGNYHEMAQLFVDVLQIWNSENDLEIKRMCHQYFCTLTPSKPDQLR 90
+L R +I +I M +M+ +F+++++ ++ D+ K++ + Y CT P KPD
Sbjct: 26 RLRYRNVIQRVIRYMTQGLDMSGVFMEMVKA-SATVDIVQKKLVYLYMCTYAPLKPDLAL 84
Query: 91 MALPIILQDLLSNSEELCILSLRTITSIDEP---EYIQEGFQHVKKLIMTTSKISIPLRK 147
+A+ + +D + + L+LR++ S+ P EYIQ+ + + + + + L
Sbjct: 85 LAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVVVLGC 144
Query: 148 AAIHSLIKMDQLDHTKVLELYYFLMDMLDYGKEEPTILVAAVTVLHEIHVSNPDMNPLQL 207
A +H+L ++D V ELY L D ++P ++V + L EI + +
Sbjct: 145 AKMHNLHGDSEVDGALVNELYSLLRD------QDPIVVVNCLRSLEEILKQE---GGVVI 195
Query: 208 TQNICFNLLEVLGKINEWDIAILFDILTTAYLPKTHSEAHHLIDLSVPKLHNLNSSVVLN 267
+ I +LL + K+++W A + + L Y P++ E +++L L + + VV+
Sbjct: 196 NKPIAHHLLNRMSKLDQWGQAEVLNFLLR-YQPRSEEELFDILNLLDSFLKSSSPGVVMG 254
Query: 268 ALKFIIYLTNYVDYIE-ERLVRKFSSSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHL 326
A K + L +++ + LVR L + ++ E+ F S H
Sbjct: 255 ATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPG---HF 311
Query: 327 EPN--NFFIEYSDPTYIKDTKLEILYLLANEENTSQILDELKGQATDIDIQMSKKSIRAI 384
+ FF YS+P YIK K+E+L L N+EN Q+L+EL+G TD+ ++ +I AI
Sbjct: 312 SSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVSADFAQAAIFAI 371
Query: 385 GNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSD 444
G +A Y V +L ELL ++I VV ++++ P + V LP +
Sbjct: 372 GGIARTYTDQC---VQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEE 428
Query: 445 SIQDSESKCAMIWIVTNHSNQLEDPIGVFRKYSDNFNTEGL-EVQLLLLNSAVKFFCRAQ 503
+IQDSE K A+IW++ H ++ + V + +N +E V++ LL ++++ F ++
Sbjct: 429 NIQDSEGKQALIWLLGVHGERIPNAPYVLEDFVENVKSETFPAVKMELLTASLRLFL-SR 487
Query: 504 SKETEQLCLKLLSGATEINDNPDLRDNAYMYWRLL 538
E + + +LL E + +RD Y+RLL
Sbjct: 488 PAECQDMLGRLLYYCIEEEKDMAVRDRGLFYYRLL 522
>Hs4758760 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1081
Score = 101 bits (252), Expect = 3e-21
Identities = 128/571 (22%), Positives = 240/571 (41%), Gaps = 77/571 (13%)
Query: 10 YKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQIWNSENDLE 69
YK H+ E++ D+ K S + +++I+A + G + LF V++ +N +E
Sbjct: 36 YKRHDDLKEML-DTNK---DSLKLEAMKRIVAMIARGK--NASDLFPAVVKNVACKN-IE 88
Query: 70 IKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDEPEYIQEGFQ 129
+K++ + Y + D +++ + L ++ + +LR ++SI P +
Sbjct: 89 VKKLVYVYLVRYAEEQQDLALLSISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMML 148
Query: 130 HVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDYGKEEPTILVAAV 189
+K+ S +S +RK A H++ K+ LD + +L + +L + T LVA
Sbjct: 149 AIKE---AASDMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLL----ADKTTLVAGS 201
Query: 190 TVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILT----TAYLPKTHSE 245
V+ V ++ + NLL + EW ++ +LT T +L T +E
Sbjct: 202 VVMAFEEVCPERIDLIHKNYRKLCNLLI---DVEEWGQVVIISMLTRYARTQFLSPTQNE 258
Query: 246 A------------------------------------------HHLIDLSVPKLHNLNSS 263
+ H L+ + L S+
Sbjct: 259 SLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSA 318
Query: 264 VVLNALKFIIYLTNYVDYIEERLVRKFSSSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPL 323
V+ A+ + + ++ R + +LL E+Q+ R
Sbjct: 319 AVVMAVAQLYF------HLGPRRKWRHRQGAGALLRSHSEVQYVVLQNVATMSIKRRGMF 372
Query: 324 IHLEP--NNFFIEYSDPTYIKDTKLEILYLLANEENTSQILDELKGQATDIDIQMSKKSI 381
EP +F+I +DPT IK KLE+L LANE N +L E + +D +I
Sbjct: 373 ---EPYLKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSMDKDFVAATI 429
Query: 382 RAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKNVLRKYPNQFDFVVPLLPQ 441
+AIG A ++ L++LL + +V E V ++K +L+ P Q ++ L +
Sbjct: 430 QAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAK 489
Query: 442 YSDSIQDSESKCAMIWIVTNHSNQL-EDPIGVFRKYSDNFNTEGLEVQLLLLNSAVKFFC 500
+D+IQ ++ +++W++ + + V RK + +F E V+L ++N A K +
Sbjct: 490 LTDNIQVPMARASILWLIGEYCEHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYL 549
Query: 501 RAQSKETEQLCLKLLSGATEINDNPDLRDNA 531
SK+T+ L +LS A + + N D+RD A
Sbjct: 550 -TNSKQTKLLTQYVLSLA-KYDQNYDIRDRA 578
>Hs4501975 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1093
Score = 99.8 bits (247), Expect = 1e-20
Identities = 127/578 (21%), Positives = 248/578 (41%), Gaps = 64/578 (11%)
Query: 1 MSESKIFYKYKAHEIRGELVSDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQ 60
+S S F + + + E + ++ S + +++I+ + G ++LF V++
Sbjct: 28 ISPSGAFGLFSSDLKKNEDLKQMLESNKDSAKLDAMKRIVGMIAKGK--NASELFPAVVK 85
Query: 61 IWNSENDLEIKRMCHQYFCTLTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDE 120
S+N +EIK++ + Y + D +++ + L ++ + +LR ++SI
Sbjct: 86 NVASKN-IEIKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRV 144
Query: 121 PEYIQEGFQHVKKLIMTTSKISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDYGKE 180
P + +K+ ++ +S +RK A H++ K+ LD E L+++++ +
Sbjct: 145 PIIVPIMMLAIKE---ASADLSPYVRKNAAHAIQKLYSLDP----EQKEMLIEVIEKLLK 197
Query: 181 EPTILVAAVTVLHEIHVSNPDMNPLQLTQNICFNLLEVLGKINEWDIAILFDILT----T 236
+ + LVA V+ V PD + L L +L + EW ++ +LT T
Sbjct: 198 DKSTLVAGSVVMAFEEVC-PDR--IDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYART 254
Query: 237 AYL--------------------------------PKTHSEAHHLIDLSV-PKLHNLNSS 263
++ P T H L+ + P L + N++
Sbjct: 255 QFVSPWKEGDELEDNGKNFYESDDDQKEKTDKKKKPYTMDPDHRLLIRNTKPLLQSRNAA 314
Query: 264 VVLNALKFIIYLTNYVDYIEERLVRKFSSSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPL 323
VV+ + +++ + S SL LL E+Q+ R
Sbjct: 315 VVMAVAQLYWHISPKSE------AGIISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMF 368
Query: 324 IHLEP--NNFFIEYSDPTYIKDTKLEILYLLANEENTSQILDELKGQATDIDIQMSKKSI 381
EP +F++ +DPT IK KLEIL LANE N S +L E + D Q + +I
Sbjct: 369 ---EPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQDKQFAAATI 425
Query: 382 RAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKNVLRKYPNQFDFVVPLLPQ 441
+ IG A ++ L+ LL + +V E V ++K +L+ P Q ++ + +
Sbjct: 426 QTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAK 485
Query: 442 YSDSIQDSESKCAMIWIVTNHSNQL-EDPIGVFRKYSDNFNTEGLEVQLLLLNSAVKFFC 500
DSI ++ +++W++ + ++ + V RK + +F +E V+L +LN K +
Sbjct: 486 LLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLGAKLYL 545
Query: 501 RAQSKETEQLCLKLLSGATEINDNPDLRDNAYMYWRLL 538
SK+T+ L +L+ + + N D+RD +L+
Sbjct: 546 -TNSKQTKLLTQYILN-LGKYDQNYDIRDRTRFIRQLI 581
>7290497 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1160
Score = 81.6 bits (200), Expect = 4e-15
Identities = 81/321 (25%), Positives = 146/321 (45%), Gaps = 25/321 (7%)
Query: 240 PKTHSEAHH-------LIDLSVPKLHNLNSSVVLNALKFIIYLT--NYVDYIEERLVRKF 290
P + S ++H L+ + P L + N+SVV+ + ++ N V I + L+R
Sbjct: 320 PSSPSNSYHIDVDHRLLLRQTKPLLQSRNASVVMAVAQLYHHVAPKNEVQLIAKALIR-- 377
Query: 291 SSSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILY 350
LL E+Q R + + +FF+ SDPT+IK KL+IL
Sbjct: 378 ------LLRSHKEVQSVVLNCIASMSTKRKA-IFEPHLKSFFVRTSDPTHIKLLKLDILT 430
Query: 351 LLANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGV 410
LA+ + S IL E + + D +I+AIG A + L+ LL
Sbjct: 431 NLASAGSISLILREFQTYISSSDRSFVAATIQAIGRCASSIKEVTETCLSGLVHLLSNHD 490
Query: 411 DYIVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPI 470
+++V E V ++K +L+ + ++ + + D I ++ A+IW++ ++ ++ P+
Sbjct: 491 EHVVAESVVVIKRLLQTKAAEHFEIITQMAKLIDYINVPAARAAIIWLIGEYNEKV--PL 548
Query: 471 ---GVFRKYSDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQLCLKLLSGATEINDNPDL 527
V RK + +F E V+L +LN VK + ++T LC + + A + N D+
Sbjct: 549 IAPDVLRKMAKSFVDEQDVVKLQVLNLGVKLYL-TNPEQTSLLCQYVFTLA-RYDPNYDV 606
Query: 528 RDNAYMYWRLLSLAGNSSEPL 548
RD A +++ A +S L
Sbjct: 607 RDRARFLRQIIFPASGTSSVL 627
>SPAC23H3.06 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 745
Score = 80.1 bits (196), Expect = 1e-14
Identities = 121/541 (22%), Positives = 223/541 (40%), Gaps = 53/541 (9%)
Query: 21 SDSGKARGSSKRKLCLRKIIANLIMGNYHEMAQLFVDVLQIWNSENDLEIKRMCHQYFCT 80
SD+GK + I+A ++ G M+ F DV+++ SEN EI+R+ H Y
Sbjct: 46 SDAGKLEA-------INFILAQMMHGE--NMSLYFPDVVKLVASENP-EIRRLVHIYLLQ 95
Query: 81 LTPSKPDQLRMALPIILQDLLSNSEELCILSLRTITSIDEPEYIQEGFQHVKKLIMTTSK 140
PD +++ + + L + ++R ++SI P +++ I T+
Sbjct: 96 YAEFNPDLALLSVNTVQKTLYDKNPLTRSTAIRVMSSIRVPAINGIVLLAIQQCITDTAD 155
Query: 141 ISIPLRKAAIHSLIKMDQLDHTKVLELYYFLMDMLDYGKEEPTILVAAVTVLHEIHVSNP 200
+R++A ++ K LD + +L + +L P ++ AA L V P
Sbjct: 156 ---RVRQSAALAITKCYSLDPSYKSQLEEHIKTLLS--DNSPIVVPAA---LFTFEVVCP 207
Query: 201 DMNPLQLTQNICFNLLEVLGKINEWD-IAILFDILTTAYL-------PKTHSEAHHLIDL 252
+ L++ + + ++N+WD + L ++ A L P THS+ L++
Sbjct: 208 EK--LEIIHPYYHRICTLFPQMNDWDKVVALKTLVRYARLTLPEPSTPSTHSDLKELLES 265
Query: 253 SVPKLHNLNSSVVLNALKFIIYL--TNYVDYIEERLVRKFSSSLTSLLNKPPEIQFXXXX 310
+L S ++ + YL +N + I E L L LL KP I
Sbjct: 266 IKSCFFSLLPSTIIAGARAFYYLAPSNQMHLIVEPL-------LQLLLEKP--IVRTTTL 316
Query: 311 XXXXXXXSRDSPLIHLEPNNFFIEYSDPTYIKDTKLEILYLLANEENTSQILDELKGQA- 369
+ L +FF+ SD K+ IL L + +N+SQIL EL
Sbjct: 317 RYISQIVYKTPELFKNHIKSFFLIASDSDDTCLLKINILSRLLDAQNSSQILPELLYYIN 376
Query: 370 TDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLELLEFGVDYIVQEVVSMLKNVLRKYP 429
+ + ++ +++A+G+ A A ++ LL LL+ IV E S L+ ++ P
Sbjct: 377 SHPNPSVASTAVKALGDFASANISMAPSCLNTLLLLLKSHNSLIVTEAASSLRLLIHNDP 436
Query: 430 NQFDFVVPLLPQYSDSIQDSESKCAMIWIVTNHSNQLEDPI-GVFRKYSDNFNTEGLEVQ 488
+ + L ++++ +K +W+++ H + + V R F E LEV+
Sbjct: 437 K--EIYLQYLAATYETLEVPRAKSVTLWLISEHILIIPRLVPDVLRIAVKTFADETLEVK 494
Query: 489 LLLLNSAVKFFCRAQSKETE----------QLCLKLLSGATEINDNPDLRDNAYMYWRLL 538
+L +V+ + + S+E + L + + + DLRD A Y L
Sbjct: 495 YQILELSVRLYVLSHSEEKQNDLESRDDVVSLLFNYVLSLIHFDMSYDLRDRARFYKELA 554
Query: 539 S 539
S
Sbjct: 555 S 555
>At3g55480_2 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1113
Score = 60.1 bits (144), Expect = 1e-08
Identities = 84/340 (24%), Positives = 149/340 (43%), Gaps = 32/340 (9%)
Query: 232 DILTTAYLPK-THSEAHH-----LIDLSVPKLHNLNSSVVLNALKFIIYLTNYVDYIEER 285
D +++A+ K T S AH+ L+ + P L + NS+VVL A + D
Sbjct: 293 DTVSSAFDTKETTSIAHNEDVKILLQCTSPLLWSNNSAVVLAAAGVQWIMAPLED----- 347
Query: 286 LVRKFSSSLTSLLNKPPEIQFXXXXXXXXXXXSRDSPLI-HLEPNNFFIEYSDPTYIKDT 344
V+K L LL ++ + S H E NFFI SD +K
Sbjct: 348 -VKKIVKPLLFLLRSSSASKYVVLCNILVFAKAVPSLFAPHFE--NFFICSSDAYQVKAY 404
Query: 345 KLEILYLLANEENTSQILDELKGQATDIDIQMSKKSIRAIGNLAVKYPHSARYSVDVLLE 404
KLE+L L+A + + IL E + D D + + ++ AIG A + +D LL
Sbjct: 405 KLEMLSLIATTSSIASILREFEDYIKDPDRRFAADTVAAIGLCAKRLMTIPTTCLDGLLA 464
Query: 405 LL---EFGVDY--------IVQEVVSMLKNVLRKYPNQFDFVVPLLPQYSDSIQDSESKC 453
L+ F D+ ++ + V ++ ++ + P + + V+ L + DSI+ + ++
Sbjct: 465 LVRQESFAGDFESADGEAGVLVQAVMSIQTMIERDPLRHEKVLIQLFRSLDSIKVAAARA 524
Query: 454 AMIWIV---TNHSNQLEDPIGVFRKY-SDNFNTEGLEVQLLLLNSAVKFFCRAQSKETEQ 509
+IW+V + + + + KY + +F +E E +L +LN+ K A++ +
Sbjct: 525 TIIWMVGVYCSLGHIIPRMLTTITKYLAWSFKSEASETKLQILNTIAKVLISAEAGDFHM 584
Query: 510 L--CLKLLSGATEINDNPDLRDNAYMYWRLLSLAGNSSEP 547
L + + E + + D+RD +LLS S EP
Sbjct: 585 LKRIVVYVFELGEYDLSYDIRDRTRFLKKLLSCKLASHEP 624
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,039,882
Number of Sequences: 60738
Number of extensions: 1624005
Number of successful extensions: 4301
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4210
Number of HSP's gapped (non-prelim): 24
length of query: 696
length of database: 30,389,216
effective HSP length: 113
effective length of query: 583
effective length of database: 23,525,822
effective search space: 13715554226
effective search space used: 13715554226
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)