ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2430 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2430 848135 846603 -511
(511 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 679 0.0
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 223 5e-58
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 204 2e-52
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 202 1e-51
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 196 9e-50
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 169 1e-41
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 163 5e-40
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 147 5e-35
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 137 3e-32
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 132 2e-30
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 130 4e-30
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 109 9e-24
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 101 3e-21
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 83 9e-16
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 80 7e-15
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 74 5e-13
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 71 4e-12
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 679 bits (1751), Expect = 0.0
Identities = 328/481 (68%), Positives = 377/481 (78%), Gaps = 4/481 (0%)
Query: 33 LKDDKSIEQEDIT--EKTTFFGNHVLDKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAA 90
L + + ++D+ E+ F+G+H L KVLRK+D+F+LPFLCCTYLLMFLDKALLNYAA
Sbjct: 45 LDESSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYAA 104
Query: 91 SMGIKDNLVGDEFSNLGTIFSASYIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXX 150
SMGIKD+L G+EFSNLGTIFSA+YIF EP YL+Q+FP+S++LG+FI WG
Sbjct: 105 SMGIKDHLKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAA 164
Query: 151 XKTYASLMIVRVLLGLFESCSAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMS 210
KTYASLM+VR LLGLFES SAVGCI ++GMYYTKSEQ+ RIG+WA QAGTGYI+GGL+S
Sbjct: 165 CKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLIS 224
Query: 211 FGFLHYHGTEFTSWQIMXXXXXXXXXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIRS 270
FGFLHYHGT FTSWQIM + YLPDNV AWFLN++EK+QV+EHIR+
Sbjct: 225 FGFLHYHGTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHIRA 284
Query: 271 NQTGLETKKIKMHQVKELLLKDKLTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQT 330
NQTGLETKK K QVKEL L DK TWPMLLLT CSQISTG+IGTFSVTITGTFGFD Y+T
Sbjct: 285 NQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYET 344
Query: 331 SLLQLPIGCVXXXXXXXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICLPLTNKIGNXXX 390
+LLQLPIG + R+ TLITTSMYIPAIIGCIV+I LPL++KIGN
Sbjct: 345 ALLQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLISLPLSHKIGNLFS 404
Query: 391 XXXXXXGSCTITNIYIWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIP 450
GSC ITNIYIWN+CNTSGYTKR+ RN +TMIVYN++CI+APQMFRAYS PRYIP
Sbjct: 405 LYLLYSGSCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIP 464
Query: 451 AKIALLVTQCVCVPLQLYIGYTSYTENRRRDKEQAESETKPEQYQFLDKTDIENRNFRYI 510
AKIALLVTQCVCVPLQLYIGY EN +RDKEQ E K +YQFLD TDIENRNFRYI
Sbjct: 465 AKIALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQERK--KYQFLDLTDIENRNFRYI 522
Query: 511 Y 511
Y
Sbjct: 523 Y 523
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 223 bits (568), Expect = 5e-58
Identities = 143/459 (31%), Positives = 223/459 (48%), Gaps = 12/459 (2%)
Query: 57 DKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDNLV--GDEFSNLGTIFSASY 114
+++++RK+D + P +C Y + FLDK +YA MG+K++L G +S GT F Y
Sbjct: 54 ERRLVRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGY 113
Query: 115 IFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAVG 174
+ E A LLQRFP+S+ L F++ WG Y + +RVLLG+ ES ++ G
Sbjct: 114 LVFEFPASLLLQRFPLSKTLCVFLVIWGFLLCMTSVAN-YPGFIALRVLLGMMESAASPG 172
Query: 175 CITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXXXX 234
I + +Y +SEQ R W A G G I+G M++G W+++
Sbjct: 173 FILLTAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRTSLPMRGWKLIFIICGVL 232
Query: 235 XXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIRSNQTGLETKKIKMHQVKELLLKDKL 294
+PDN KAWFL E+++ V++ +R+N+ G+ K++Q KE +L D
Sbjct: 233 AIFLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETML-DIR 291
Query: 295 TWPMLLLTGCSQISTGSIGTF-SVTITGTFGFDSYQTSLLQLPIG-CVXXXXXXXXXXXX 352
TW M + + I G IGTF S+ I GT G+D+ QT L+ LP G C
Sbjct: 292 TWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSL 351
Query: 353 GRFSQFTLITTSMYIPAIIGCIVMICLPLTNKIGNXXXXXXXXXGSCTITNIYIWNTCNT 412
+ L T + I I C++ P ++ + I + N
Sbjct: 352 FIHKRMVLATITTCIALIGSCLLSFAGPPRAQLAGYYLLMVSPGAMIVMFAII---SSNA 408
Query: 413 SGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIALLVTQCVCVPLQLYIGYT 472
SGYTK++ + +I Y + ++ PQ F+A P Y+PAK ++ + + Y
Sbjct: 409 SGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALYYV 468
Query: 473 SYTENRRRDKEQAES--ETKPEQYQFLDKTDIENRNFRY 509
++ EN+RRD+ AE E +P +F D TD EN +FRY
Sbjct: 469 NWRENKRRDQLAAEGKIEHRPNA-EFEDLTDFENLDFRY 506
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 204 bits (520), Expect = 2e-52
Identities = 133/459 (28%), Positives = 223/459 (47%), Gaps = 12/459 (2%)
Query: 58 KKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDN--LVGDEFSNLGTIFSASYI 115
++VL K+D+ ++P +C TY++ +LDK L+YAA G+K + + G +S++ T+F A Y+
Sbjct: 67 RRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMKTDTHIDGHTYSSMTTLFYAGYL 126
Query: 116 FAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAVGC 175
A+ A L+Q+ +S + + W + SL+ +R L G+FE+
Sbjct: 127 VAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLAGIFEASITPAF 186
Query: 176 ITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXXXXX 235
I + M+Y + EQ R W A G IIG ++S+G H HG + SW+ +
Sbjct: 187 INITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGLGHIHG-KVASWRYV-FIVIGLM 244
Query: 236 XXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIRSNQTGLETKKIKMHQVKELLLKDKLT 295
+ ++P N KA FL+ +EK +E +R N+TGLE K+ K E L D
Sbjct: 245 SLGWGVVFVFIPSNPSKARFLSSREKRIALERVRDNRTGLENKQFKWKHAYEAFL-DPQV 303
Query: 296 WPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLPIGCVXXXXXXXXXXXXGRF 355
+ L TG I+ G IG FS I G++ +++L +P+G + F
Sbjct: 304 IMITLFTGVCMITNG-IGVFSTLIIKGLGYNELHSAVLNMPLGAIEVAAMFISGVLCKVF 362
Query: 356 SQ-FTLITTSMYIPAIIGCIVMICLPLTNKIGNXXXXXXXXXGSCTITNIYIWNTCNTSG 414
LI M + GC+++ +P +N G + + + N +G
Sbjct: 363 KNGRLLIGVFMNCLTLAGCLMIWKIPDSNPYGRLVGVWFTMWVPASSALLLSLISSNVAG 422
Query: 415 YTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIALLVTQCVCVPLQLYI-GYTS 473
YTK+ + + Y++ IV+PQ+F++ P YI A++V+ C+ + + + GY
Sbjct: 423 YTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIEGIQAMIVSLCIIIAIAFVLTGYYI 482
Query: 474 YTENRRRDKEQAESETKPEQY---QFLDKTDIENRNFRY 509
Y EN+RRD+ AE + E +F+D TD + FRY
Sbjct: 483 Y-ENKRRDRLLAEDPSLGESIKNEEFMDLTDRQQPKFRY 520
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 202 bits (513), Expect = 1e-51
Identities = 141/496 (28%), Positives = 236/496 (47%), Gaps = 31/496 (6%)
Query: 32 ELKDDKSIEQEDITEKTTFFGNH-VLDKKVLRKL----DIFVLPFLCCTYLLMFLDKALL 86
EL + S QED+ F H ++DK + RKL D++V+P LC ++DK+
Sbjct: 13 ELGEKGSDSQEDVA--VIFAEKHPIIDKSLNRKLKLKTDLWVMPLLCLISAFQYMDKSTS 70
Query: 87 NYAASMGIKD--NLVGDEFSNLGTIFSASY-IFAEPFAVYLLQRFPVSRVLGSFIICWGX 143
NY++ MGI+ N+VG++++ +GT F + +F+ P + LLQ+FP+S+V +FI+ WG
Sbjct: 71 NYSSIMGIRTDLNMVGNQYNWVGTSFYLGFMVFSLPLST-LLQKFPLSKVTSAFIVAWGI 129
Query: 144 XXXXXXXXKTYASLMIVRVLLGLFESCSAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGY 203
+YAS + R LLG+ ES + +Y K EQ R+ + A G G
Sbjct: 130 LMTLTCLVHSYASYIATRTLLGILESVITPAFVLFIAQWYRKEEQFFRMAFLVAWNGLGG 189
Query: 204 IIGGLMSFGFLH---YHGTEFTSWQIMXXXXXXXXXXXXXXXYFYLPDNVPKAWFLNEKE 260
+IGG MS+G + + W+I+ + ++PD KAWFL+EKE
Sbjct: 190 LIGGSMSYGLYKRELENNLTMSPWRILFIITGLITIINGVFIFIHIPDEPSKAWFLSEKE 249
Query: 261 KVQVIEHIRSNQTGLETKKIKMHQVKELLLKDKLTWPMLLLTGCSQISTGSIGTFSVTIT 320
K V++ + ++ GL +KK K +Q+ E +D + L I G + FS +
Sbjct: 250 KDLVLKRLDTDHAGLGSKKFKKYQILE-ACRDVRMYLYFFLQIAVAIPNGGLSNFSSIML 308
Query: 321 GTFGFDSYQTSLLQLPIGCVXXXXXXXXXXXXGRFSQFT-----LITTSMYIPAIIGCIV 375
G+ + L+ +P + G +FT + + I G ++
Sbjct: 309 KNLGYVKGKALLMNMPTSSI----SFAALTLFGLIPEFTNRRMDIALVGLAINLTSGSLI 364
Query: 376 MICLPLTNKIGNXXXXXXXXXGSCTITNIYIWN--TCNTSGYTKRLARNGLTMIVYNIAC 433
P ++ G I I I + + N++G+TK++ + ++MI Y +
Sbjct: 365 AFAKPTHAQLAG-----YWLFGISPIPYICILSCISSNSAGHTKKVFMSAVSMIGYCVGN 419
Query: 434 IVAPQMFRAYSYPRYIPAKIALLVTQCVCVPLQLYIGYTSYTENRRRDKEQAESETKPEQ 493
+V PQ FR+ P+Y AK++ +V CV + + + I + ENRRRD++ + +
Sbjct: 420 MVGPQTFRSTQAPKYQGAKVSFVVCYCVAIFIIIAIYAVNVRENRRRDEKNEYLSNELSE 479
Query: 494 YQFLDKTDIENRNFRY 509
D TD EN FRY
Sbjct: 480 EDKKDLTDFENPEFRY 495
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 196 bits (497), Expect = 9e-50
Identities = 140/473 (29%), Positives = 221/473 (46%), Gaps = 25/473 (5%)
Query: 57 DKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDNLV--GDEFSNLGTIFSASY 114
D+K+ K+D + P +C Y + F+DK + AA MG++ +L GD++S + + F Y
Sbjct: 74 DRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGY 133
Query: 115 IFAEPFAV-YLLQRFP-VSRVLGSFIICWGXXXXXXXXXKT-YASLMIVRVLLGLFESCS 171
+F V ++ QR +S++L FI+ WG Y S +++RVLLG ES
Sbjct: 134 LFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVV 193
Query: 172 AVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFG-FLHYHGTEFTSWQIMXXX 230
+ Y+ EQ R+ W G G I+ +++G ++H W+ +
Sbjct: 194 TPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVI 253
Query: 231 XXXXXXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIRSNQTGLETKKIKMHQVKELLL 290
+ ++PD+ KA FL+++EK+ V++ IRSNQ G +IK +Q+ E L
Sbjct: 254 TGVITIFIGILIFLWIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIKKYQIIE-AL 312
Query: 291 KDKLTWPMLLLTGCSQISTGSIGTF-SVTITGTFGFDSYQTSLLQLPIGCVXX----XXX 345
KD TW L T S I G I +F S+ + FG+ S +T L+ LP G V
Sbjct: 313 KDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFG 372
Query: 346 XXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICLP--LTNK-----IGNXXXXXXXXXGS 398
+ F S I A + ++ C+ TN G
Sbjct: 373 ILAVYAANKKIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYISPVSFI 432
Query: 399 CTITNIYIWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIALLVT 458
C ++NI + N+SGY+K+ + + ++ Y A + PQ F A P+Y AK+A++V
Sbjct: 433 CVLSNI----SANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKVAMVVC 488
Query: 459 QCVCVPLQLYIGYTSYTENRRRDKEQAES--ETKPEQYQFLDKTDIENRNFRY 509
V + L + + EN+RRDK AE + E +F D TD EN NFRY
Sbjct: 489 YAVMIVLLSILLIVNLRENKRRDKIAAERGFPEETENLEFSDLTDFENPNFRY 541
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 169 bits (427), Expect = 1e-41
Identities = 130/488 (26%), Positives = 211/488 (42%), Gaps = 45/488 (9%)
Query: 57 DKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDN--LVGDEFSNLGTIFSASY 114
+ K+ KL I++L L +++F+ KA L+Y+ +G+ D+ + ++++NL T+F Y
Sbjct: 91 ESKLKWKLYIYLLLMLGFLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGY 150
Query: 115 IFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAVG 174
I + Y++Q FP+ + +G W Y L+ +R LG ESC
Sbjct: 151 IVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTESCLLPA 210
Query: 175 CITVNGMYYTKSEQT--QRIGYWAAQAGTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXX 232
GM++T EQ Q + +W + G I G +++G L + W++
Sbjct: 211 MEATMGMFFTHQEQAFLQPV-FWISCLSCG-IPAGFIAYG-LEFVTKSIAPWKLFMIITG 267
Query: 233 XXXXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIR-SNQTGLETKKIKMHQVKELLLK 291
+FY PDN KA FL ++EK+ I+ +R S + G+E K K HQ E L K
Sbjct: 268 GITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQFIEAL-K 326
Query: 292 DKLTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLPIGCVXXXXXXXXXXX 351
D +TW +S ++ F S S L + V
Sbjct: 327 DPITWLFTFAAFTLMLSN------NLAYQQNLIFTSLNVSDLNSTLVGVALAGYNTVSAI 380
Query: 352 XGRFSQFTLITTSMY------IPAIIGCIVMICLPLTNKIGNXXXXXXXXXGSCTITNIY 405
F+ + + S Y +P+I G I + LP +N+IG T
Sbjct: 381 IATFAMYLIPNQSAYHAMFWMLPSITGGIAFVALPWSNRIGELATMIIASDFGITYIIAL 440
Query: 406 IWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPA-----KIALLVTQC 460
W T ++GYTK+L R + M+ Y IA I++PQ++++ PRY PA +A VT
Sbjct: 441 GWTTATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVTPI 500
Query: 461 VCVPLQLYIGYTSYTENRRRDKEQAES--ETKPEQY-----------------QFLDKTD 501
+ + ++ + + +DK+ AE ET + Y LD TD
Sbjct: 501 IYLVARVILARRNKQRKELKDKKIAEGSLETIEKTYVDTVDEFGNPVKVLIDNSMLDLTD 560
Query: 502 IENRNFRY 509
+EN NF Y
Sbjct: 561 MENLNFVY 568
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 163 bits (413), Expect = 5e-40
Identities = 130/479 (27%), Positives = 205/479 (42%), Gaps = 32/479 (6%)
Query: 57 DKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDN--LVGDEFSNLGTIFSASY 114
DK++ KL VL L +++++DKA L+Y++ +G+ ++ + ++++++ T+F +
Sbjct: 78 DKRLRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGF 137
Query: 115 IFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAVG 174
+ + LLQRFPVS+ + + W ++ LM +R LGL ES
Sbjct: 138 VIGQIPGHMLLQRFPVSKFVAASTALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPT 197
Query: 175 CITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXXXX 234
GM++ SEQ ++ I G +++G + Y + W++
Sbjct: 198 MEATIGMFFPHSEQALLQPFFYISCYGCNIPAGFIAYG-VQYAKNTISPWKLFMIIVGGI 256
Query: 235 XXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIR-SNQTGLETKKIKMHQVKELLLKDK 293
+FY PDN A FL +KE++ ++ +R SN +G+E+K K +QV E L KD
Sbjct: 257 TFFLTIGLFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTFKKYQVIEAL-KDP 315
Query: 294 LTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLPIG--CVXXXXXXXXXXX 351
+TW C+Q+S ++ T D T + G CV
Sbjct: 316 VTWLFTFHVFCNQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYMMSV 375
Query: 352 XGRFSQFTLITTSMYIPAIIGCIVMICLPLTNKIGNXXXXXXXXXGSCTITNIYIWNTCN 411
S F YIP+I G I + + +KIG W T +
Sbjct: 376 IKNQSAFH--GAIWYIPSIAGGIACVAMSWDHKIGELAAIIIASNFGIPFIISLGWTTAS 433
Query: 412 TSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIALLVTQCVCVPLQLYIGY 471
+GYTK+L R + MI Y IA I+ PQM+++ PRY PA I +V P L I
Sbjct: 434 CAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSPFVLLI-- 491
Query: 472 TSYTENRRRDKEQAESETKPEQYQ---------------------FLDKTDIENRNFRY 509
+ RR K A E EQY+ LD TD EN +F Y
Sbjct: 492 IRWILVRRNKKRLALLEQNKEQYEKTWIETIDSSGNHVSGFYENSMLDLTDQENLSFIY 550
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 147 bits (370), Expect = 5e-35
Identities = 114/490 (23%), Positives = 204/490 (41%), Gaps = 45/490 (9%)
Query: 57 DKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDN--LVGDEFSNLGTIFSASY 114
+KK+ RKL + + F+ LL+++DKA L+Y + +G ++ L + ++ + T+F +
Sbjct: 48 EKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTLFYVGF 107
Query: 115 IFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAVG 174
+ YL Q+ P+ + LG + W ++ ++ +R LGL ES
Sbjct: 108 AIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLTESVVIPI 167
Query: 175 CITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXXXX 234
IT GM++ SE+ ++ A I G +++G LH + W+I
Sbjct: 168 LITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITNPSISLWKIFTIIIGGL 227
Query: 235 XXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIR-SNQTGLETKKIKMHQVKELLLKDK 293
+ P+N F + +E+V +I ++ S + +E K K Q +E +KD
Sbjct: 228 TFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKKSQFRE-AMKDY 286
Query: 294 LTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLPIGCVXXXXXXXXXXXXG 353
+TW L Q++ ++ G G D+ ++L+ +
Sbjct: 287 ITWLFGLFFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVAGAGFAVVCAFIATLMLA 346
Query: 354 RFSQFTLITTSMY-IPAIIGCIVMICLPLTNKIGNXXXXXXXXXGSCTITNIY------- 405
++ + +T + +PA++G I LP NKIG C I+
Sbjct: 347 KWKNISALTAIFWTLPALVGSIAAAALPWDNKIG-------ILANICMAGQIFGIPFIIA 399
Query: 406 -IWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIALLVTQCVCVP 464
W + + SGYTK+L R+ +++ IA I++PQ++R PR++PA I +V P
Sbjct: 400 LSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQIVLSFSLAP 459
Query: 465 -LQLYIGYTSYTENRRRDK------------------------EQAESETKPEQYQFLDK 499
+ L I + N +R K E+ + T D
Sbjct: 460 AILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVVTHENNLAVFDL 519
Query: 500 TDIENRNFRY 509
TD+EN F Y
Sbjct: 520 TDLENETFIY 529
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 137 bits (346), Expect = 3e-32
Identities = 107/455 (23%), Positives = 193/455 (41%), Gaps = 8/455 (1%)
Query: 40 EQEDITEKTTFFGNHVLDKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDNL- 98
E ED+T + + +H ++++ RK D +LP L YL LDK+ ++ A + G+ +L
Sbjct: 34 EGEDVTTEV-YILDHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLG 92
Query: 99 -VGDEFSNLGTIFSASYIF-AEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYAS 156
VGD+++ + +IF ++ A PF+ YL +RF +R+L F++ +G K +
Sbjct: 93 FVGDQYNIMISIFYIPFVLCAFPFS-YLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGG 151
Query: 157 LMIVRVLLGLFESCSAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHY 216
+M VR LG+ ES G + +Y ++E +R+ + A A GGL+++G H
Sbjct: 152 MMAVRWFLGMAESAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHI 211
Query: 217 HGTEFTSWQIMXXXXXXXXXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIRSNQTGLE 276
G + WQ + + LP +V A FL ++EK I ++ +
Sbjct: 212 KGGKLQGWQYLFLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAI 271
Query: 277 TKKIKMHQVKELLLKDKLTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLP 336
++K+ Q + K + LL + SI + I GF S T+L+ +
Sbjct: 272 SEKLSFKQ-SLTVFKHPIAILWLLEEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVA 330
Query: 337 IGCVXXXXXXXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICLPLTNKIGNXXXXXXXXX 396
++ + +IG IV + + N IG
Sbjct: 331 PAISGAIWLLVFAFISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMT 390
Query: 397 GSCTITNIY--IWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIA 454
+++ W NT ++R + + + N+ +V+ +FR P+Y+PA
Sbjct: 391 AGAAASSVLTSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGI 450
Query: 455 LLVTQCVCVPLQLYIGYTSYTENRRRDKEQAESET 489
+ + L I + +NRRRD Q +T
Sbjct: 451 TAGFGGLGILLVASISVYMFFDNRRRDNAQGVKKT 485
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 132 bits (331), Expect = 2e-30
Identities = 114/502 (22%), Positives = 212/502 (41%), Gaps = 29/502 (5%)
Query: 26 LSSAAAELKDDKSIEQEDITEKTTFFG----NHVLDKKVLRKLDIFVLPFLCCTYLLMFL 81
L + + + K + + E+E + T G +H ++K+VLRK+DI+++P + Y L L
Sbjct: 46 LHNRSHDKKSELATEREIMATTTDDDGIPSPSHPMEKRVLRKMDIYLIPLMGMLYFLSNL 105
Query: 82 DKALLNYAASMGI-KD-NLVGDEFSNLGTIFSASYIFAEPFAVYLLQRFPVSRVLGSFII 139
DK+ + A G+ KD +LVG +++ T+F A+Y+ +P LL+ ++ +
Sbjct: 106 DKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVLFDPIGTNLLKIMGPPLMMSICLT 165
Query: 140 CWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAVGCITVNGMYYTKSEQTQRIGYWAAQA 199
C+G K YA L++VR+LLG FE + Y + + R + + A
Sbjct: 166 CFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRREQYALRFAFVFSAA 225
Query: 200 GTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXXXXXXXXXXXXYFYLPDNVPKAWFLNEK 259
GGL+++G G+ WQ + F L N+ +WF N++
Sbjct: 226 CLSSSFGGLIAYGCSKISGS-LKDWQYIYIVEGCISLGFVPFYAFGLSKNLEDSWFFNKE 284
Query: 260 EKVQVIEHIRSNQTGLETKKIKMHQVKELLLKDKLTWPMLLLTGCSQISTGSIGTFSVTI 319
EK + E ++ T +K + QV + +KD TW + ++T + F I
Sbjct: 285 EKEYISERYKTMNTFDPDEKFEWFQVWQ-AVKDVKTWASAVALFGIDLTTFGLTVFLPII 343
Query: 320 TGTFGFDSYQTSLLQLPIGCVXXXXXXXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICL 379
+ GF + + L+ +PI + R + P I+G + +
Sbjct: 344 ITSMGFTNVRAQLMTVPIYFLTAIVFFICAVWSDRI--------KLRSPFILGACLTTSI 395
Query: 380 PLTNKIGNXXXXXXXXXGSCTITNIYI-------WNTCNTSGYTKRLARNGLTMIVYNIA 432
+ +G+ IY+ W + NT Y KR G+ + + +
Sbjct: 396 GIAIVLGSQVHGVRYFGVYILCMGIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGS 455
Query: 433 CIVAPQMFRAYSYPRYIPA---KIALLVTQCVCVPLQLYIGYTSYTENRRRDKEQAESET 489
+V+ Q+F A PRYI +A V +Q+++ Y + ++ ++
Sbjct: 456 GLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQIFL-YKRENDKKKAIIDRCNELG 514
Query: 490 KPEQYQFLDKTDIENRNFRYIY 511
+P Y ++ +N F+Y+Y
Sbjct: 515 EPIPYD--ERLSDKNPEFKYMY 534
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 130 bits (328), Expect = 4e-30
Identities = 107/441 (24%), Positives = 176/441 (39%), Gaps = 10/441 (2%)
Query: 56 LDKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKD--NLVGDEFSNLGTIFSAS 113
++KK+L K+D+ + P + YL+ FLD++ + AA G+ + +L G+ + +IF
Sbjct: 49 VEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVL 108
Query: 114 YIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESCSAV 173
YI E +V L++R SR+L W +Y L+ R++LGL E C
Sbjct: 109 YILVETPSVVLVKRIKASRMLAFISFAWSMTVLFSGFMSSYGGLIATRLILGLLEGCLFP 168
Query: 174 GCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHYHGTEFTSWQIMXXXXXX 233
+YT+ EQ QR+ Y A AG GGL ++ H WQ +
Sbjct: 169 ALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGL 228
Query: 234 XXXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIEHIRSNQTGLETKKIKMHQVKELLLKDK 293
F LPD + AWFL +E+ I N + + +V++ KD
Sbjct: 229 VSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRK-AFKDP 287
Query: 294 LTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLPIGCVXXXXXXXXXXXXG 353
+ C+ + +F I GF QT+ + +P+
Sbjct: 288 KVYVSATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTNYMTIPVYIAGVISFLFVAWLSD 347
Query: 354 RFSQFTLITTSMYIPAIIGCIVMICLPLTNKIGNXXXXXXXXXGSCTITNIYI-WNTCNT 412
R + S +G I+M L + G + + W N
Sbjct: 348 RTQLRAVYLISASTVVAVGYIIM--LASDSNAAKYTATYIIAIGCYIGPGLNLGWLNNNV 405
Query: 413 SGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIALLVTQCVCVPLQLYI--G 470
+G+ KR G+ + N + IVA Q++R+ + P+YI L CV V Y+
Sbjct: 406 AGHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTL--GCVIVGGLAYVVMF 463
Query: 471 YTSYTENRRRDKEQAESETKP 491
++ N++RD+ A E P
Sbjct: 464 FSLRYVNKKRDERCARGEFDP 484
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 109 bits (273), Expect = 9e-24
Identities = 105/485 (21%), Positives = 191/485 (38%), Gaps = 16/485 (3%)
Query: 34 KDDKSIEQEDITEKTTFFGNHVLDKK---VLRKLDIFVLPFLCCTYLLMFLDKALLNYAA 90
+ +K I + + + H+ + +L +LD+ + P + YL+ FLD++ + A
Sbjct: 22 ESEKVISRSNTASPISIENTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAK 81
Query: 91 SMGIKDNLV--GDEFSNLGTIFSASYIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXX 148
G+ ++L GD+F+ + ++F ++I E L+++ R+L +I +
Sbjct: 82 VAGLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFT 141
Query: 149 XXXKTYASLMIVRVLLGLFESCSAVGCITVN-GMYYTKSEQTQRIGYWAAQAGTGYIIGG 207
+ L+ R++LG E+ C+ + M Y++ E RI Y A + GG
Sbjct: 142 GFCHNFGGLLAARLVLGFCEA-GLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGG 200
Query: 208 LMSFGFLHYHGT-EFTSWQIMXXXXXXXXXXXXXXXYFYLPDNVPKAWFLNEKEKVQVIE 266
L ++ LH G F W+ + YF +P+++ KAWFL++ + + +
Sbjct: 201 LFAYAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVAVYFIIPNDITKAWFLSKTHQEMMRK 260
Query: 267 HIRSNQTGLETKKIKMHQVKELLLKDKLTWPMLLLTGCSQISTGSIGTFSVTITGTFGFD 326
LE VK K+ L G G TF I G+
Sbjct: 261 RQLERAADLEAAHFDWKGVKSAFTDFKVYLYALSEFGQDTCLYG-FSTFLPAIISGMGYT 319
Query: 327 SYQTSLLQLPIGCVXXXXXXXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICLPLTNKIG 386
S + +P+ + RF +I I I+G I+++ NK
Sbjct: 320 SLSVQYMTIPVYILGAATYIAASFLSDRFHHRGIILIIGNIFPIVGYILLLACQ-NNKSV 378
Query: 387 NXXXXXXXXXGSCTITNIYI-WNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSY 445
G T + + W + N + + KR L + + N + I+A Q++R
Sbjct: 379 LYFACYLCSVGVYTGAGLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYR--YP 436
Query: 446 PRYIPAKIALLVTQCVCVPLQLYIGYTSYTENRRRDKEQAESETKPEQYQFLDKTDIENR 505
P+YI + L+ + L + + +N ++ K A S T Q D D
Sbjct: 437 PKYIAGHLTSLIAIFISTVLHVVNIFFLKHQNSKKQKSLASSSTIDLSEQPKDDKD---A 493
Query: 506 NFRYI 510
F YI
Sbjct: 494 RFHYI 498
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 101 bits (251), Expect = 3e-21
Identities = 100/426 (23%), Positives = 179/426 (41%), Gaps = 19/426 (4%)
Query: 33 LKDDKSIEQE---DITEKTTFFGNHVLDKK----VLRKLDIFVLPFLCCTYLLMFLDKAL 85
++++K I + DI+E T F + ++KK ++RKLD +++P Y L FLD+A
Sbjct: 4 MEEEKVISKSTSVDISEGT--FDDITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRAN 61
Query: 86 LNYAASMGIKDNLV--GDEFSNLGTIFSASYIFAEPFAVYLLQRFPVSRVLGSFIICWGX 143
+ AA +G+K++L ++S ++F A+YI AE +V L+++F L + II W
Sbjct: 62 IGNAAVVGLKEDLKLQAYQYSAAVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSL 121
Query: 144 XXXXXXXXKTYASLMIVRVLLGLFESCSAVGCITVN-GMYYTKSEQTQRIGYWAAQAGTG 202
+ Y SL++ R+LLG+ E C+++ M Y + EQ +R+ Y +
Sbjct: 122 VTIFTCFVRHYWSLVLTRLLLGICEG-GFFPCLSLYISMTYKREEQGKRLAYLYVCSCFS 180
Query: 203 YIIGGLMSFGFLHY-HGTEFTSWQIMXXXXXXXXXXXXXXXYFYLPDNVPKAWFLNEKEK 261
GGL++ G + +W + F LPD+ A FLN +EK
Sbjct: 181 GAFGGLIATGLTKIPKSSGLPNWGWLYIIEGLISAISALWILFCLPDDPSTARFLNPREK 240
Query: 262 VQVIEHIRSNQTGLETKKIKMHQVKELLLKDKLTWPMLLLTGCSQISTGSIGTFSVTITG 321
+ Q + + Q ++ KD + ++ C + I TF +I
Sbjct: 241 ELMKIRAEQRQKYMGSPNFDWTQFRK-AFKDPKMYMSCVIQFCQDLVLYGISTFLPSILK 299
Query: 322 -TFGFDSYQTSLLQLPIGCVXXXXXXXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICLP 380
G+ S + +P+ + R + M + G I++ L
Sbjct: 300 LELGYSSLAAQYMSVPVYALGGISVYVICLLSDRTNIRGWFIIGMNFFGLAGFIIL--LA 357
Query: 381 LTNKIGNXXXXXXXXXGSC-TITNIYIWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQM 439
TN N T+ W N + + +R G + N+A ++A Q+
Sbjct: 358 TTNSAANYVATYLIALPLYPTVALNITWINNNMAPHYRRATALGCNQTIGNLAGVIAGQV 417
Query: 440 FRAYSY 445
+R+ Y
Sbjct: 418 YRSSPY 423
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 83.2 bits (204), Expect = 9e-16
Identities = 59/241 (24%), Positives = 109/241 (44%), Gaps = 10/241 (4%)
Query: 50 FFGNHVLDKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDNLV--GDEFSNLG 107
++G + +++K+L K+D F+L + C +Y + +LD++ +N A G++++L G+E ++
Sbjct: 14 YYGLNKVEQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDIN 73
Query: 108 TIFSASYIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLF 167
+F+ YI + Y LQR P I WG + +LMI+R + +
Sbjct: 74 VVFTCGYIIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVA 133
Query: 168 ESCSAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMS---FGFLHYHGTEFTSW 224
E+ + G + G +Y +SE +R G ++A G + G + L+ G + W
Sbjct: 134 EASTFAGTHYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKG-GLSGW 192
Query: 225 QIMXXXXXXXXXXXXXXXYFYLPD--NVPKAWFLNEKEKVQVIEHI--RSNQTGLETKKI 280
+ + F PD KA + E+EK + + R + L K I
Sbjct: 193 RWLFIIDGILTIPLSLYGLFLFPDVPETTKAPYFTEQEKELSFKRLPARPKKKPLTLKAI 252
Query: 281 K 281
K
Sbjct: 253 K 253
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 80.1 bits (196), Expect = 7e-15
Identities = 98/479 (20%), Positives = 187/479 (38%), Gaps = 30/479 (6%)
Query: 57 DKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDNLVGD-----EFSNLG-TIF 110
+KK++RK+D+ + FL + FLD N A + + DN + D NLG T++
Sbjct: 70 EKKLVRKMDLKI--FLWVFIMFAFLDLIRKNIARA--VSDNFIVDLKMNTNDYNLGQTVY 125
Query: 111 SASYIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFESC 170
++ +E L +RF RV+ I+ W K + R LLG+ +
Sbjct: 126 LVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGG 185
Query: 171 SAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMSFGFLHYHGT-EFTSWQIMXX 229
I YYT +E T R+ ++ I+G L++ G + G WQ +
Sbjct: 186 FIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFI 245
Query: 230 XXXXXXXXXXXXXYFYLPDNVP-----------KAWFLNEKEKVQVIEHIRSNQTGLETK 278
FYL P K+ F +EK+ V +R + + +
Sbjct: 246 IEGFLSLSVGVAS-FYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMS 304
Query: 279 KIKMHQVKELL--LKDKLTWPMLLLTGCSQISTGSIGTFSVTITGTFGFDSYQTSLLQLP 336
+ KE+L L + WP+ + + IS ++G++ I + + ++ +++L +P
Sbjct: 305 NRQPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLNYSTFLSNILAIP 364
Query: 337 IGCVXXXXXXXXXXXXGRFSQFTLITTSMYIPAIIGCIVMICLPL-TNKIGNXXXXXXXX 395
+ + + +L + + + ++ LP TN
Sbjct: 365 GQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTGIL 424
Query: 396 XGSCTITNIYIWNTCNTSGYTKRLARNGLTMIVYNIACIVAPQMFRAYSYPRYIPAKIAL 455
T + + W + ++ R L + + I+A M+R P Y L
Sbjct: 425 GLPYTHSILAGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKIL 484
Query: 456 LVTQCVCVPLQLYIGYTSYTENRRRDKEQAESETKPEQYQFLDKT---DIENRNFRYIY 511
L C + + + + + N+ +D++ S TK EQ +LD T ++ ++R+I+
Sbjct: 485 LGFTCFNICMAVATKFYYISRNKYKDRKW-NSMTKEEQINYLDTTKDKGMKRLDYRFIH 542
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 73.9 bits (180), Expect = 5e-13
Identities = 60/260 (23%), Positives = 113/260 (43%), Gaps = 13/260 (5%)
Query: 52 GNHVLDKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASMGIKDNL--VGDEFSNLGTI 109
G +KK+L KLD+ + + C Y + +LD +N A G+K++L G++ + +
Sbjct: 123 GTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVM 182
Query: 110 FSA-SYIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXXXKTYASLMIVRVLLGLFE 168
++ + IF PF +YL + P++ VL S +CW + L +R +G FE
Sbjct: 183 YTVGNIIFQLPFLIYL-NKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFE 241
Query: 169 SCSAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYI-IGGLMSFGFLHYHGTE-FTSWQI 226
+ S + + G +Y E +R ++ G + GG+ S + +G W+
Sbjct: 242 APSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWRW 301
Query: 227 MXXXXXXXXXXXXXXXYFYLPDNVPKAW--FLNEKEKVQVIEHIRSNQTGLETKKIKMHQ 284
++ LP + + FL + E + ++ NQTG + K+
Sbjct: 302 NFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFD 361
Query: 285 VK--ELLLKDKLTWPMLLLT 302
+K + + D W + +LT
Sbjct: 362 IKLWKTIFSD---WKIYILT 378
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 70.9 bits (172), Expect = 4e-12
Identities = 48/189 (25%), Positives = 82/189 (42%), Gaps = 3/189 (1%)
Query: 33 LKDDKSIEQEDITEKTTFFGNHVLDKKVLRKLDIFVLPFLCCTYLLMFLDKALLNYAASM 92
+K+ KSI Q ++ ++ + + +L K+D+FVL F+C Y + ++D+ A
Sbjct: 2 MKESKSITQHEVERESVSSKRAIKKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAYIS 61
Query: 93 GIKDNL--VGDEFSNLGTIFSASYIFAEPFAVYLLQRFPVSRVLGSFIICWGXXXXXXXX 150
G+K++L VG++ + T+F YI +L P L WG
Sbjct: 62 GMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPRIWLSFCTFAWGLLTLGMYK 121
Query: 151 XKTYASLMIVRVLLGLFESCSAVGCITVNGMYYTKSEQTQRIGYWAAQAGTGYIIGGLMS 210
++ + +R LFESC+ G V G +Y + E R + G + G M
Sbjct: 122 VTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQ 181
Query: 211 FG-FLHYHG 218
F H +G
Sbjct: 182 TSIFTHLNG 190
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.140 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,591,333
Number of Sequences: 60738
Number of extensions: 968696
Number of successful extensions: 3008
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2938
Number of HSP's gapped (non-prelim): 20
length of query: 511
length of database: 30,389,216
effective HSP length: 111
effective length of query: 400
effective length of database: 23,647,298
effective search space: 9458919200
effective search space used: 9458919200
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)