ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2479 good C KOG0557 Energy production and conversion Dihydrolipoamide acetyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2479 865604 866818 405
(405 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR193c [C] KOG0557 Dihydrolipoamide acetyltransferase 328 1e-89
SPCC1259.09c [C] KOG0557 Dihydrolipoamide acetyltransferase 168 1e-41
At3g13930 [C] KOG0557 Dihydrolipoamide acetyltransferase 124 2e-28
YNL071w [C] KOG0557 Dihydrolipoamide acetyltransferase 119 8e-27
At1g54220 [C] KOG0557 Dihydrolipoamide acetyltransferase 115 1e-25
SPCC794.07 [C] KOG0557 Dihydrolipoamide acetyltransferase 112 8e-25
At3g52200 [C] KOG0557 Dihydrolipoamide acetyltransferase 108 2e-23
CE09597 [C] KOG0557 Dihydrolipoamide acetyltransferase 105 1e-22
Hs4505699 [C] KOG0557 Dihydrolipoamide acetyltransferase 100 3e-21
Hs17458911 [C] KOG0557 Dihydrolipoamide acetyltransferase 100 4e-21
Hs21630255 [C] KOG0557 Dihydrolipoamide acetyltransferase 100 7e-21
7293036 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ac... 86 1e-16
7297250 [C] KOG0557 Dihydrolipoamide acetyltransferase 85 2e-16
CE01115 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ac... 73 9e-13
At1g34430 [C] KOG0557 Dihydrolipoamide acetyltransferase 73 9e-13
At3g25860 [C] KOG0557 Dihydrolipoamide acetyltransferase 67 6e-11
Hs4503265 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ... 53 9e-07
CE14480 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxog... 52 2e-06
>YGR193c [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 410
Score = 328 bits (840), Expect = 1e-89
Identities = 179/403 (44%), Positives = 253/403 (62%), Gaps = 11/403 (2%)
Query: 9 RACLRQLHQCR-----TMLKAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVET 63
++C R L +C +L + F MPAMSPTME+GG+V WK+K G+ FSAGDV+LEVET
Sbjct: 12 KSCTRYLTKCNYHASAKLLAVKTFSMPAMSPTMEKGGIVSWKYKVGEPFSAGDVILEVET 71
Query: 64 DKATIDVEAQDDGKLAKILKENGAKDIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKP 123
DK+ IDVEA DDGKLAKILK+ G+KD+ VGEPIAYIADVDDDLAT++ P+ +K
Sbjct: 72 DKSQIDVEALDDGKLAKILKDEGSKDVDVGEPIAYIADVDDDLATIKLPQEANT-ANAKS 130
Query: 124 VETKKEEAKPVEKTDKK-KQTSASKTPSKNGSVQANASQTLFPSVLSLLEENNISTADAL 182
+E KK A E T + K+ + + + +GS QAN QTL PSV LL ENNIS AL
Sbjct: 131 IEIKKPSADSTEATQQHLKKATVTPIKTVDGS-QANLEQTLLPSVSLLLAENNISKQKAL 189
Query: 183 DKIKATGPNGRILKGDVLAYLGKISQDSLNKVTEYIKSHEKLDLTNIELRPARETXXXXX 242
+I +G NGR+LKGDVLAYLGKI QDS+NKVTE+IK +E+LDL+NI+ +
Sbjct: 190 KEIAPSGSNGRLLKGDVLAYLGKIPQDSVNKVTEFIKKNERLDLSNIKPIQLKPKIAEQA 249
Query: 243 XXXXXXXXXXLPLVLSEQITLHVPENVTYSQLSAAIASYVKECSFLAHDEPLTNDASELY 302
P+ EQ+ H P ++ + +LS ++ S++KE +H PL + S+ +
Sbjct: 250 QTKAADKPKITPVEFEEQLVFHAPASIPFDKLSESLNSFMKEAYQFSHGTPLMDTNSKYF 309
Query: 303 DPLFEELLVQEPTKPRFKVTYNIVDLEPTPRHRTSSPQPDIFDLLSGTTTQELQQEASAV 362
DP+FE+L+ P +PRFK +Y+++ + + + Q DIFDLL+G + V
Sbjct: 310 DPIFEDLVTLSPREPRFKFSYDLMQIPKANNMQDTYGQEDIFDLLTG--SDATASSVRPV 367
Query: 363 SKQQQTRHEYALNVSVAV-DESLTDAKQRAENFVAQLSNLELF 404
K ++EY L ++V+V ++ DA+ +A+ F+ + LE F
Sbjct: 368 EKNLPEKNEYILALNVSVNNKKFNDAEAKAKRFLDYVRELESF 410
>SPCC1259.09c [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 456
Score = 168 bits (426), Expect = 1e-41
Identities = 95/209 (45%), Positives = 135/209 (64%), Gaps = 12/209 (5%)
Query: 24 AQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILK 83
A F MPA+SPTME G + W FK GD+F +GD+LLEVETDKAT+DVE QD+G LAK+L
Sbjct: 35 ASMFRMPALSPTMEEGNITKWHFKEGDSFKSGDILLEVETDKATMDVEVQDNGILAKVLI 94
Query: 84 ENGAKDIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQT 143
E G+ +IPVG+ IA +AD +D+L LE PK EA E + + KEE KP+ + + K
Sbjct: 95 EKGS-NIPVGKNIAIVADAEDNLKDLELPKD-EASSEEQSFSSSKEEVKPIVQDRETKSN 152
Query: 144 SASKTPSKNGSVQAN--ASQTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDVLA 201
K+ S QAN +++ PSV L+ + I + I ATGP+GR+LKGDVLA
Sbjct: 153 VEHKSTS-----QANDAVNKSFLPSVSYLIHQYKIENPWS---IPATGPHGRLLKGDVLA 204
Query: 202 YLGKISQDSLNKVTEYIKSHEKLDLTNIE 230
++GKI + + + +++++ E LD + +E
Sbjct: 205 HVGKIDKGVPSSLQKFVRNLEVLDFSGVE 233
>At3g13930 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 508
Score = 124 bits (312), Expect = 2e-28
Identities = 80/212 (37%), Positives = 116/212 (53%), Gaps = 14/212 (6%)
Query: 25 QAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKE 84
Q GMP++SPTM G + W K GD + G+VL EVETDKAT+++E ++G LAKI+KE
Sbjct: 86 QEIGMPSLSPTMTEGNIARWLKKEGDKVAPGEVLCEVETDKATVEMECMEEGFLAKIVKE 145
Query: 85 NGAKDIPVGEPIAYIADVDDDLATLEFPKPVE----AKKESKPVETKKEEAKPVEKTDKK 140
GAK+I VGE IA + +DD+ + P A E+KP + +E K VEK
Sbjct: 146 EGAKEIQVGEVIAITVEDEDDIQKFKDYTPSSDTGPAAPEAKPAPSLPKEEK-VEKPASA 204
Query: 141 KQTSASKTPSKNGSVQANASQTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDVL 200
+ SK S + AS P L E+NN+ L IK TGP GRI+K DV
Sbjct: 205 PEAKISKPSSAPSEDRIFAS----PLARKLAEDNNV----PLSSIKGTGPEGRIVKADVE 256
Query: 201 AYLGKISQDSLNKVTEYIKSHEKLDLTNIELR 232
+L ++ S +V + + + +D+ + ++R
Sbjct: 257 DFLETTAKPS-KQVDSKVPALDYVDIPHTQIR 287
>YNL071w [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 482
Score = 119 bits (298), Expect = 8e-27
Identities = 84/215 (39%), Positives = 117/215 (54%), Gaps = 15/215 (6%)
Query: 3 RLAIKNRACLRQLHQCRTMLKAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVE 62
R ++ R+ QL + + GMPA+SPTM +G + W K GD S G+V+ E+E
Sbjct: 13 RSSVLTRSLRLQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIAEIE 72
Query: 63 TDKATIDVEAQDDGKLAKILKENGAKDIPVGEPIA-YIADVDDDLATLEFPKPVEAKKES 121
TDKA +D E Q+DG LAKIL G KDIPV +PIA Y+ D D A +F K ++ +S
Sbjct: 73 TDKAQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAFKDF-KLEDSGSDS 131
Query: 122 KPVETKKEEAKPVEKTDKKKQTSASKT----PSKNGSVQANASQTLFPSVL--SLLEENN 175
K TK + A+P + +KK++ A +T P S A +F S L ++ E
Sbjct: 132 K-TSTKAQPAEP--QAEKKQEAPAEETKTSAPEAKKSDVAAPQGRIFASPLAKTIALEKG 188
Query: 176 ISTADALDKIKATGPNGRILKGDVLAYLGKISQDS 210
IS D + TGP GRI K D+ +YL K S+ S
Sbjct: 189 ISLKD----VHGTGPRGRITKADIESYLEKSSKQS 219
>At1g54220 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 424
Score = 115 bits (288), Expect = 1e-25
Identities = 68/187 (36%), Positives = 104/187 (55%), Gaps = 9/187 (4%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
MP++SPTM G + W K GD + G+VL EVETDKAT+++E ++G LAKI+K G+K
Sbjct: 1 MPSLSPTMTEGNIARWLKKEGDKVAPGEVLCEVETDKATVEMECMEEGYLAKIVKAEGSK 60
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKT 148
+I VGE IA + ++D+ + P + ++ P + + A P K +K KQ S+
Sbjct: 61 EIQVGEVIAITVEDEEDIGKFKDYTP-SSTADAAPTKAEPTPAPP--KEEKVKQPSSPPE 117
Query: 149 PSKNGSVQANASQTLFPSVLS--LLEENNISTADALDKIKATGPNGRILKGDVLAYLGKI 206
P + +F S L+ L E+NN+ +D I+ TGP GRI+K D+ YL
Sbjct: 118 PKASKPSTPPTGDRVFASPLARKLAEDNNVPLSD----IEGTGPEGRIVKADIDEYLASS 173
Query: 207 SQDSLNK 213
+ + K
Sbjct: 174 GKGATAK 180
>SPCC794.07 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 483
Score = 112 bits (281), Expect = 8e-25
Identities = 64/171 (37%), Positives = 97/171 (56%), Gaps = 8/171 (4%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
MPA+SPTM G + ++ K GD GDVL E+ETDKA ID E QD+G LAKIL E G K
Sbjct: 58 MPALSPTMTTGNIGAFQKKIGDKIEPGDVLCEIETDKAQIDFEQQDEGYLAKILIETGTK 117
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKT 148
D+PVG+P+A + + D+A + ++ + ++ +E++ P + K+ +S S
Sbjct: 118 DVPVGKPLAVTVENEGDVAAMADFTIEDSSAKEPSAKSGEEKSAPSSEKQSKETSSPSNV 177
Query: 149 PSKNGSVQANASQTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDV 199
+ + AS P L EE ++ L +I+ +GPNGRI+K D+
Sbjct: 178 SGEERGDRVFAS----PLARKLAEEKDLD----LSQIRGSGPNGRIIKVDI 220
>At3g52200 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 637
Score = 108 bits (269), Expect = 2e-23
Identities = 57/123 (46%), Positives = 76/123 (61%), Gaps = 4/123 (3%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
MPA+SPTM G VV W K GD GDVL E+ETDKAT++ E+Q++G LAKIL G+K
Sbjct: 90 MPALSPTMSHGNVVKWMKKEGDKVEVGDVLCEIETDKATVEFESQEEGFLAKILVTEGSK 149
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKK--QTSAS 146
DIPV EPIA + + +DD+ + P +E ++ K + + KP E T +K Q AS
Sbjct: 150 DIPVNEPIAIMVEEEDDIKNV--PATIEGGRDGKEETSAHQVMKPDESTQQKSSIQPDAS 207
Query: 147 KTP 149
P
Sbjct: 208 DLP 210
Score = 99.4 bits (246), Expect = 9e-21
Identities = 69/184 (37%), Positives = 99/184 (53%), Gaps = 26/184 (14%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
MPA+SPTM +G + W K GD GDV+ E+ETDKAT++ E+ ++G LAKIL G+K
Sbjct: 217 MPALSPTMNQGNIAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYLAKILIPEGSK 276
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKT 148
D+ VG+PIA I +D ++E K A S V+T KE P DK + A T
Sbjct: 277 DVAVGKPIALIV---EDAESIEAIKSSSA--GSSEVDTVKE--VPDSVVDKPTERKAGFT 329
Query: 149 PSKNGSVQANASQTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDVLAYL--GKI 206
+ P+ L+ E+ + + I+A+GP G +LK DV+A + GK
Sbjct: 330 -------------KISPAAKLLILEHGLEAS----SIEASGPYGTLLKSDVVAAIASGKA 372
Query: 207 SQDS 210
S+ S
Sbjct: 373 SKSS 376
>CE09597 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 507
Score = 105 bits (262), Expect = 1e-22
Identities = 75/230 (32%), Positives = 113/230 (48%), Gaps = 16/230 (6%)
Query: 14 QLHQCRTMLKAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQ 73
+L+ + K +PA+SPTME G VV W+ K GD S GD+L E+ETDKAT+ E
Sbjct: 67 RLYSSGNLPKHNRVALPALSPTMELGTVVSWQKKEGDQLSEGDLLCEIETDKATMGFETP 126
Query: 74 DDGKLAKILKENGAKDIPVGEPIAYIADVDDDLATL-EFPKPVEAKKESKP-VETKKEEA 131
++G LAKIL + G+KD+P+G+ + I D + D+A +F + S P E E A
Sbjct: 127 EEGYLAKILIQEGSKDVPIGKLLCIIVDNEADVAAFKDFKDDGASSGGSAPAAEKAPEPA 186
Query: 132 KPVEKTDKKKQTSASKTPS--KNGSVQANAS--QTLFPSVLSLLEENNISTADALDKIKA 187
KP + + PS K+ + ++S + P L EN + L +
Sbjct: 187 KPAASSQPSPPAQMYQAPSVPKSAPIPHSSSGRVSASPFAKKLAAENGLD----LSGVSG 242
Query: 188 TGPNGRILKGDVLAYLGKISQDSLNKVTEYIKSHEKLDLTNIELRPARET 237
+GP GRIL D+ K + + T+ + D T+I L R+T
Sbjct: 243 SGPGGRILASDLSQAPAK---GATSTTTQAVSGQ---DYTDIPLSNMRKT 286
>Hs4505699 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 501
Score = 100 bits (250), Expect = 3e-21
Identities = 66/185 (35%), Positives = 96/185 (51%), Gaps = 20/185 (10%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
MP++SPTME G +V W K G+ SAGD L E+ETDKA + ++A DDG LAKI+ E G+K
Sbjct: 61 MPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSK 120
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKT 148
+I +G I I + +D +E PK V P +K E +P + Q S
Sbjct: 121 NIRLGSLIGLIVEEGEDWKHVEIPKDV----GPPPPVSKPSEPRP----SPEPQIS---I 169
Query: 149 PSKNGSVQANASQTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDVLAYL----- 203
P K + L P+ ++LE++++ + ATGP G K D L +
Sbjct: 170 PVKKEHIPGTLRFRLSPAARNILEKHSLDASQG----TATGPRGIFTKEDALKLVQLKQT 225
Query: 204 GKISQ 208
GKI++
Sbjct: 226 GKITE 230
>Hs17458911 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 647
Score = 100 bits (249), Expect = 4e-21
Identities = 63/177 (35%), Positives = 93/177 (51%), Gaps = 8/177 (4%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
+PA+SPTM G V W+ K G+ S GD+L E+ETDKATI E Q++G LAKIL G +
Sbjct: 223 LPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTR 282
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKT 148
D+P+G P+ I + + D++ +P E + KP + PV Q A
Sbjct: 283 DVPLGTPLCIIVEKEADISAFADYRPTEV-TDLKP-QAPPPTPPPVAAVPPTPQPLAPTP 340
Query: 149 PSKNGSVQANASQTLFPSVLS--LLEENNISTADALDKIKATGPNGRILKGDVLAYL 203
+ + A +F S L+ L E I L ++K TGP+GRI K D+ +++
Sbjct: 341 SAPCPATPAGPKGRVFVSPLAKKLAVEKGID----LTQVKGTGPDGRITKKDIDSFV 393
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/147 (31%), Positives = 73/147 (49%), Gaps = 16/147 (10%)
Query: 25 QAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKE 84
Q +P++SPTM+ G + W+ K GD + GD++ EVETDKAT+ E+ ++ +AKIL
Sbjct: 92 QKVPLPSLSPTMQAGTIARWEKKEGDQINEGDLIAEVETDKATVGFESLEECYMAKILVA 151
Query: 85 NGAKDIPVGEPIAYIADVDDDLATLEFPKPVEAKK----ESKPVETKKEEAKPVEKTDKK 140
G +D+P+G I T+ P+ +EA K +S T + P
Sbjct: 152 EGTRDVPIGAIIC---------ITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATAS 202
Query: 141 KQTSASKTPSKNGSVQANASQTLFPSV 167
T +++ P GS Q L P++
Sbjct: 203 PPTPSAQAP---GSSYPPHMQVLLPAL 226
>Hs21630255 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 613
Score = 99.8 bits (247), Expect = 7e-21
Identities = 62/177 (35%), Positives = 91/177 (51%), Gaps = 8/177 (4%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
+PA+SPTM G V W+ K G+ S GD+L E+ETDKATI E Q++G LAKIL G +
Sbjct: 190 LPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTR 249
Query: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKT 148
D+P+G P+ I + + D++ +P E + KP + PV Q A
Sbjct: 250 DVPLGTPLCIIVEKEADISAFADYRPTEV-TDLKP-QVPPPTPPPVAAVPPTPQPLAPTP 307
Query: 149 PSKNGSVQANASQTLF--PSVLSLLEENNISTADALDKIKATGPNGRILKGDVLAYL 203
+ + A +F P L E I L ++K TGP+GRI K D+ +++
Sbjct: 308 STPCPATPAGPKGRVFVDPLAKKLAVEKGID----LTQVKGTGPDGRITKKDIDSFV 360
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/147 (31%), Positives = 73/147 (49%), Gaps = 16/147 (10%)
Query: 25 QAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKE 84
Q +P++SPTM+ G + W+ K GD + GD++ EVETDKAT+ E+ ++ +AKIL
Sbjct: 59 QKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVA 118
Query: 85 NGAKDIPVGEPIAYIADVDDDLATLEFPKPVEAKK----ESKPVETKKEEAKPVEKTDKK 140
G +D+P+G I T+ P+ +EA K +S T + P
Sbjct: 119 EGTRDVPIGAIIC---------ITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATAS 169
Query: 141 KQTSASKTPSKNGSVQANASQTLFPSV 167
T +++ P GS Q L P++
Sbjct: 170 PPTPSAQAP---GSSYPPHMQVLLPAL 193
>7293036 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 462
Score = 85.5 bits (210), Expect = 1e-16
Identities = 63/207 (30%), Positives = 107/207 (51%), Gaps = 20/207 (9%)
Query: 1 MFRLAIKNRACLRQ-LHQCRTMLKAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLL 59
+ R I RA LR+ LH ++ K +F + + + V +W K GDT D L
Sbjct: 14 LLRNCISQRAALRRCLHVTSSLDKTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQFDNLC 73
Query: 60 EVETDKATIDVEAQDDGKLAKILKENGAKDIPVGEPIAYIADVDDDLATLEFPKPVEAKK 119
EV++DKA++ + ++ DGK+ KI + + VG+P+ +D D+ + +P ++
Sbjct: 74 EVQSDKASVTITSRYDGKITKIHHKIDEIAL-VGKPL-----LDFDVVNEDEDEPEDSSS 127
Query: 120 ESKPVETKKEEAKPVEKTDKKKQTSASKTPSKNGSVQANASQTLFPSVLSLLEENNISTA 179
S + + ++K+ AS TP++ G V A+ PSV L +E+ + A
Sbjct: 128 SSSSTSSDSS----ASENEEKQSAEASATPTE-GRVIIPAT----PSVRRLAKEHQLDLA 178
Query: 180 DALDKIKATGPNGRILKGDVLAYLGKI 206
K+ ATG NGR+LKGD+L +LG++
Sbjct: 179 ----KVPATGKNGRVLKGDILEFLGQV 201
>7297250 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 512
Score = 85.1 bits (209), Expect = 2e-16
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 19/182 (10%)
Query: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
+PA+SPTMERG +V W+ K GD + GD+L E+ETDKAT+ E ++G LAKIL + G K
Sbjct: 85 LPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEEGFLAKILIQGGTK 144
Query: 89 DIPVGE----------PIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTD 138
D+PVG+ +A A+ DD A P A + A P
Sbjct: 145 DVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAAA----APPPPPPP 200
Query: 139 KKKQTSASKTPSKNGSVQANASQTLFPSVLSLLEENNISTADALD-KIKATGPNGRILKG 197
+A+ P+ + A + ++ S ++ ++ A L + K +G +G I G
Sbjct: 201 AAAPAAAAPPPAPAAAPAAAGTGRVYASPMA----KRLAEAQQLRLQGKGSGVHGSIKSG 256
Query: 198 DV 199
D+
Sbjct: 257 DL 258
>CE01115 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 448
Score = 72.8 bits (177), Expect = 9e-13
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 26/196 (13%)
Query: 41 VVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAKDIPVGEPIAYIA 100
V +W K GDT S D + EV++DKA + + + DG + K+ E + +A
Sbjct: 47 VKEWYVKEGDTISQFDKVCEVQSDKAAVTISCRYDGIVKKLYHE-----------VDGMA 95
Query: 101 DVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQTSASKTPSKNGSVQANAS 160
V L +E VE +P + KKE A + K A ++ G V A
Sbjct: 96 RVGQALIDVEIEGNVE-----EPEQPKKEAASSSPEAPKSSAPKAPESAHSEGKVLAT-- 148
Query: 161 QTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDVLAYLGKISQDSLNKVTEYIKS 220
P+V + EN I A+ ++ TG +GR+LK DVL +LG++ D + T +
Sbjct: 149 ----PAVRRIAIENKIKLAE----VRGTGKDGRVLKEDVLKFLGQVPADHTSGSTNIRTT 200
Query: 221 HEKLDLTNIELRPARE 236
H+ ++ P +E
Sbjct: 201 HQAPQPSSKSYEPLKE 216
>At1g34430 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 465
Score = 72.8 bits (177), Expect = 9e-13
Identities = 61/194 (31%), Positives = 88/194 (44%), Gaps = 27/194 (13%)
Query: 23 KAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKIL 82
K + MPA+S TM G +V W GD + G+ ++ VE+DKA +DVE DG LA I+
Sbjct: 38 KIREIFMPALSSTMTEGKIVSWVKSEGDKLNKGESVVVVESDKADMDVETFYDGYLAAIM 97
Query: 83 KENGAKDIPVGEPIAYIADVDDDLATLEF---------------PKPVEAKKESKPVETK 127
E G PVG IA +A+ +D++A + P A E+ K
Sbjct: 98 VEEGGV-APVGSAIALLAETEDEIADAKAKASGGGGGGDSKAPPASPPTAAVEAPVSVEK 156
Query: 128 KEEAKPVEKTDKKKQTSASKTPSKNGSVQANASQTLFPSVLSLLEENNISTADALDKIKA 187
K A PV K +++ P+ G + AS P L +E + A +
Sbjct: 157 KVAAAPV---SIKAVAASAVHPASEGGKRIVAS----PYAKKLAKELKVELAG----LVG 205
Query: 188 TGPNGRILKGDVLA 201
+GP GRI+ DV A
Sbjct: 206 SGPMGRIVAKDVEA 219
>At3g25860 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 480
Score = 66.6 bits (161), Expect = 6e-11
Identities = 50/178 (28%), Positives = 82/178 (45%), Gaps = 12/178 (6%)
Query: 23 KAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKIL 82
K + MPA+S TM G +V W G+ + G+ ++ VE+DKA +DVE DG LA I+
Sbjct: 54 KIREIFMPALSSTMTEGKIVSWIKTEGEKLAKGESVVVVESDKADMDVETFYDGYLAAIV 113
Query: 83 KENGAKDIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTDKKKQ 142
G + PVG I +A+ + ++ + ++K SK + E P
Sbjct: 114 VGEG-ETAPVGAAIGLLAETEAEI------EEAKSKAASKSSSSVAEAVVPSPPPVTSSP 166
Query: 143 TSASKTPSKNGSVQANASQTL-FPSVLSLLEENNISTADALDKIKATGPNGRILKGDV 199
A P+ +V +T+ P L +++ + ++ + TGP GRI DV
Sbjct: 167 APAIAQPAPVTAVSDGPRKTVATPYAKKLAKQHKVD----IESVAGTGPFGRITASDV 220
>Hs4503265 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 482
Score = 52.8 bits (125), Expect = 9e-07
Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 40/168 (23%)
Query: 41 VVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAKDIPVGEPIAYIA 100
V +W K GDT S D + EV++DKA++ + ++ DG + K+ + IAY+
Sbjct: 81 VKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNL--------DDIAYVG 132
Query: 101 DVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKTD---KKKQTSASKTPSKNGSVQA 157
D+ T EA K+S+ + E T K ++T A+
Sbjct: 133 KPLVDIET-------EALKDSEEDVVETPAVSHDEHTHQEIKGRKTLAT----------- 174
Query: 158 NASQTLFPSVLSLLEENNISTADALDKIKATGPNGRILKGDVLAYLGK 205
P+V L ENNI L ++ +G +GRILK D+L YL K
Sbjct: 175 -------PAVRRLAMENNIK----LSEVVGSGKDGRILKEDILNYLEK 211
>CE14480 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 452
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 13/137 (9%)
Query: 30 PAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK- 88
PA + ++ G + W + GD + +++ E+ETDK +++V A G + + L E+GAK
Sbjct: 69 PAFAESISEGDI-RWLKQKGDHVNEDELVAEIETDKTSVEVPAPQAGTIVEFLVEDGAKV 127
Query: 89 -----------DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKKEEAKPVEKT 137
G A + E KP AK++SKP T KPV
Sbjct: 128 TAKQKLYKLQPGAGGGSSSAPAKEEPKSAPAKEESKPAPAKEDSKPAVTAAAPPKPVSGD 187
Query: 138 DKKKQTSASKTPSKNGS 154
K ++ PS S
Sbjct: 188 IPKSAPPVARPPSTPSS 204
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.128 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,569,419
Number of Sequences: 60738
Number of extensions: 982896
Number of successful extensions: 5058
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 5020
Number of HSP's gapped (non-prelim): 21
length of query: 405
length of database: 30,389,216
effective HSP length: 109
effective length of query: 296
effective length of database: 23,768,774
effective search space: 7035557104
effective search space used: 7035557104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)