ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2539 good K KOG1861 Transcription Leucine permease transcriptional regulator
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2539 887150 885285 -622
(622 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR045c [K] KOG1861 Leucine permease transcriptional regulator 252 1e-66
SPBC2A9.11c [K] KOG1861 Leucine permease transcriptional regulator 175 2e-43
CE29249 [K] KOG1861 Leucine permease transcriptional regulator 151 2e-36
Hs22052277 [K] KOG1861 Leucine permease transcriptional regulator 146 8e-35
7297767 [K] KOG1861 Leucine permease transcriptional regulator 146 1e-34
At2g39340 [K] KOG1861 Leucine permease transcriptional regulator 144 3e-34
>YPR045c [K] KOG1861 Leucine permease transcriptional regulator
Length = 470
Score = 252 bits (644), Expect = 1e-66
Identities = 133/338 (39%), Positives = 208/338 (61%), Gaps = 10/338 (2%)
Query: 291 KIAAQDEKSRRLERLKRFASPEPLTSTSKRVKIDDDDSYSDLNAITNKAYKFDKNKPIVG 350
++ DE RR R +RF S P +T+ +++D +++LNAI++K++++DK +VG
Sbjct: 135 EMGGSDELERRKRRAERF-SQGPSATTNSNDNLNED--FANLNAISSKSHQYDKKIHVVG 191
Query: 351 QCQVLEKKYLRLTSEPDPAKVRPLSILIKALDWIVTKFHSGSCSYQYFCDQLKSIRQDLK 410
+CQ LEK YLRLTSEP+P +RP +IL K ++ K+ S + +Y Y CDQ KS+RQDL+
Sbjct: 192 RCQTLEKSYLRLTSEPNPDLIRPPNILQKMYCLLMDKYQSKTATYTYLCDQFKSMRQDLR 251
Query: 411 VQMIENDFTVTVYKTHARAALENGDVGEYNQCQSSLKPLFEKDNIDKSDLPEFISYRILY 470
VQMIEN FT+ VY+THAR ALENGD+GE+NQCQ+ + LFE I K EFI Y +LY
Sbjct: 252 VQMIENSFTIKVYQTHARIALENGDLGEFNQCQNRIMALFENPTIPKKSYSEFICYSVLY 311
Query: 471 HMMTSDHSSINQLHFQLLTT-LSHMYDNEMIQRALKMSEAQIENNYHTFMRIYQQTKGPE 529
M+T D+ SI+ L +L+ S + ++E ++ ++S+ ++ NYH FM+ Y + E
Sbjct: 312 SMLTEDYPSISHLKLKLIDDGSSEILEDEHVKMIFELSDMKLVGNYHYFMKNYLKLHKFE 371
Query: 530 RHLVNQFIKKERLNALNCMCKAYARLPLQFLAPELHFNDXXXXXXXXXXXXXIQFMVVPE 589
+ L+N F+ E+L L +CK+Y ++ L F+ E +FN +F++ +
Sbjct: 372 KCLINSFLNLEKLIFLTIICKSYNQVNLDFVKSEFNFNSIEETTNFLNEQNLTEFILNKQ 431
Query: 590 ------SDPNEIYLDCKSCRSTIIKHFGDARRIDIKGQ 621
N L+ K CR +I+++ +++IDIKGQ
Sbjct: 432 ITDSNGKSSNIKILNTKGCRVQLIQNYMKSKKIDIKGQ 469
>SPBC2A9.11c [K] KOG1861 Leucine permease transcriptional regulator
Length = 395
Score = 175 bits (444), Expect = 2e-43
Identities = 117/334 (35%), Positives = 171/334 (51%), Gaps = 19/334 (5%)
Query: 296 DEKSRRLER------LKRFASPEPLTSTSKRVKIDDDDSYSDLNAITNKAYKFDKNKPIV 349
++K R++E+ + + + KR + ++ S S NA + + +N I+
Sbjct: 74 EDKKRKVEKPVSGNQFSLLSEEDEVDKKEKRRRRFENGSRSQNNAKSEELKVNPENGAII 133
Query: 350 GQCQVLEKKYLRLTSEPDPAKVRPLSILIKALDWIVTKFHSGSCSYQYFCDQLKSIRQDL 409
G+ LEK+YLRLTS PDP VRPL +L + L+ + K+ +Y Y CDQ KS+RQDL
Sbjct: 134 GRSTELEKRYLRLTSAPDPDTVRPLPVLKQTLELLKKKWKEEK-NYAYICDQFKSLRQDL 192
Query: 410 KVQMIENDFTVTVYKTHARAALENGDVGEYNQCQSSLKPLFEKDNIDKSDLPEFISYRIL 469
VQ I+N+F+V VY+ HAR ALE GDVGEYNQCQ+ L L+ + EF++YRIL
Sbjct: 193 TVQRIQNEFSVLVYEIHARIALEKGDVGEYNQCQTQLFHLYSFG--IPGNTKEFLAYRIL 250
Query: 470 YHMMTSDHSSINQLHFQLLTTLSHMYDNEMIQRALKMSEAQIENNYHTFMRIYQQTKGPE 529
Y + T + S +N L L N + AL++ A +Y+ F +Y
Sbjct: 251 YMLFTKNRSEMNSL---LANLKEEDKTNAAVTHALEVRSAMATGDYYKFFHLYLVAPNMG 307
Query: 530 RHLVNQFIKKERLNALNCMCKAY-ARLPLQFLAPELHFNDXXXXXXXXXXXXXIQFMVVP 588
+L++ FI++ER+ A+ MCKAY L ++FLA L F + V
Sbjct: 308 GYLMDLFIERERVQAMIMMCKAYRPSLTMEFLANTLAFEEMEDCVNFFRSCNA----VYD 363
Query: 589 ESDPNEIYLDCKSCRSTIIKHFGDARRIDIKGQI 622
DPN I + K K +DIKGQI
Sbjct: 364 SKDPNRILM--KESTDRFEKCMKKHAVVDIKGQI 395
>CE29249 [K] KOG1861 Leucine permease transcriptional regulator
Length = 646
Score = 151 bits (382), Expect = 2e-36
Identities = 91/262 (34%), Positives = 153/262 (57%), Gaps = 20/262 (7%)
Query: 291 KIAAQDEKSRRLERLKRFASPEPLTSTSKRVKIDDDDSYSDLNAITNKAYKFDKNKPIVG 350
K+A D ++RR +R +RFA E L + SK +++ + F + + I G
Sbjct: 358 KVAGGDTEARREDRARRFA--ETLYNVSKP-------------SVSVPQHYFRRGQVIRG 402
Query: 351 QCQVLEKKYLRLTSEPDPAKVRPLSILIKALDWIVTKFHSGSCSYQYFCDQLKSIRQDLK 410
CQ +EK + RLT+ P+P++VRPL +L +L + K+ + + Y Y Q++SIRQDL
Sbjct: 403 TCQNIEKSFFRLTAAPNPSEVRPLEVLRLSLQNVRDKYRARA-EYSYLTSQMRSIRQDLT 461
Query: 411 VQMIENDFTVTVYKTHARAALENGDVGEYNQCQSSLKPLFEKDNIDKSDLPEFISYRILY 470
VQ+I N+FTV VY+ +AR +LEN D E+N+CQS LK L+ + + ++ EF++YR+LY
Sbjct: 462 VQVIRNEFTVEVYEINARISLENADREEFNKCQSQLKLLYSEIE-NCANQAEFVAYRLLY 520
Query: 471 HMMTSDHSSINQLHFQLLTTLSHMYDNEMIQRALKMSEAQIENNYHTFMRIYQQTKGPER 530
++ + IN L +L L +N+ ++ AL + +A NNY F R+++
Sbjct: 521 YIAMDNQIDINALLRELTPELK---ENDCVEFALNVRKAVTMNNYVKFFRLFKNAPRMCP 577
Query: 531 HLVNQFIKKERLNALNCMCKAY 552
++++ F+ +ER AL + KA+
Sbjct: 578 YIMDLFVDRERKKALGIITKAF 599
>Hs22052277 [K] KOG1861 Leucine permease transcriptional regulator
Length = 582
Score = 146 bits (369), Expect = 8e-35
Identities = 91/225 (40%), Positives = 126/225 (55%), Gaps = 14/225 (6%)
Query: 348 IVGQCQVLEKKYLRLTSEPDPAKVRPLSILIKALDWIVTKFHSGSCSYQYFCDQLKSIRQ 407
IVG C + K YLRLT PDP+ VRP+++L K+L + + Y + C+Q+KSIRQ
Sbjct: 258 IVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEKQ-DYAFACEQMKSIRQ 316
Query: 408 DLKVQMIENDFTVTVYKTHARAALENGDVGEYNQCQSSLKPLFEKDNIDKSDLPEFISYR 467
DL VQ I +FTV VY+THAR ALE GD E+NQCQ+ LK L+ ++ ++ EF +YR
Sbjct: 317 DLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAENL--PGNVGEFTAYR 374
Query: 468 ILYHMMTSDHSSINQLHFQLLTTLSHMYDNEMIQRALKMSEAQIENNYHTFMRIYQQTKG 527
ILY++ T + I +L + + + AL + A NYH F R+Y
Sbjct: 375 ILYYIFTKNSGDITT---ELAYLTRELKADPCVAHALALRTAWALGNYHRFFRLYCHAPC 431
Query: 528 PERHLVNQFIKKERLNALNCMCKAY----ARLPLQF----LAPEL 564
+LV++F +ER AL M K Y + LPL F LAP L
Sbjct: 432 MSGYLVDKFADRERKVALKAMIKTYVVPSSLLPLLFPSFRLAPPL 476
>7297767 [K] KOG1861 Leucine permease transcriptional regulator
Length = 874
Score = 146 bits (368), Expect = 1e-34
Identities = 96/280 (34%), Positives = 144/280 (51%), Gaps = 24/280 (8%)
Query: 293 AAQDEKSRRLERLKRFA----------------SPEPLTSTSKRVKIDDDDSYSDLNAI- 335
A D+ +R +R RF+ SP LT+ + K+ +A
Sbjct: 550 AVDDDTARLQQRAARFSQQGSSSAKKSVVAIASSPFGLTTAKNKKKMVQQHQQHQRSAFY 609
Query: 336 --TNKAYKFDK-NKPIVGQCQVLEKKYLRLTSEPDPAKVRPLSILIKALDWIVTKFHSGS 392
T A D + IVG C+ LEK +LRLT P P++VRP+ +L +L + K+ +
Sbjct: 610 EDTEAASGIDLLDLHIVGTCRDLEKSFLRLTKAPSPSEVRPVEVLTHSLVNVKGKWRANQ 669
Query: 393 CSYQYFCDQLKSIRQDLKVQMIENDFTVTVYKTHARAALENGDVGEYNQCQSSLKPLFEK 452
Y Y CDQLKSIRQDL VQ I + FTV VY+THAR A+E GD E+NQCQ+ LK L+ +
Sbjct: 670 -DYHYACDQLKSIRQDLTVQGIRDQFTVEVYETHARIAMEKGDHEEFNQCQTQLKMLYME 728
Query: 453 DNIDKSDLPEFISYRILYHMMTSDHSSINQLHFQLLTTLSHMYDNEMIQRALKMSEAQIE 512
++ EF +YRILY++ T + I + + + + +N +I AL+ A
Sbjct: 729 IGGKNANALEFTAYRILYYIFTKNTLDITTV---MRSITADQRENPVIAHALQFRSAWSL 785
Query: 513 NNYHTFMRIYQQTKGPERHLVNQFIKKERLNALNCMCKAY 552
NY +Y+ H++ F+++ER AL + K+Y
Sbjct: 786 GNYCKLFSLYRTAPLMSGHMIEWFLERERKAALRVIIKSY 825
>At2g39340 [K] KOG1861 Leucine permease transcriptional regulator
Length = 989
Score = 144 bits (364), Expect = 3e-34
Identities = 104/297 (35%), Positives = 158/297 (53%), Gaps = 48/297 (16%)
Query: 295 QDEKSRRLERLKRFASPEPLT--------------STSKRVKIDDDDSYS------DLNA 334
+D +S+R E+++ + LT +T+ R+ D+S S D +A
Sbjct: 642 RDSRSKRFEKIQGHSRGNDLTKPKNANVGNLHSRRATALRLSKVFDESGSRAVEDIDWDA 701
Query: 335 ITNKAYKFDKNKPIVGQCQVLEKKYLRLTSEPDPAKVRPLSILIKALDWIVTKFHSGSCS 394
+T K G CQ +EK+YLRLTS PDPA VRP +L KAL + +
Sbjct: 702 LTVK-----------GTCQEIEKRYLRLTSAPDPATVRPEDVLEKALIMV----QDSQKN 746
Query: 395 YQYFCDQLKSIRQDLKVQMIENDFTVTVYKTHARAALENGDVGEYNQCQSSLKPLFEKDN 454
Y + CDQLKSIRQDL VQ I N T VY+THAR ALE GD+ EYNQC S LK L+ +
Sbjct: 747 YLFKCDQLKSIRQDLTVQRIHNHLTAKVYETHARLALEAGDLPEYNQCLSQLKTLY-AEG 805
Query: 455 IDKSDLPEFISYRILYHMMTSDHSSINQLHFQLLTTLSHMYD----NEMIQRALKMSEAQ 510
++ L EF +Y +LY + HS+ N+ +LL+++S + + +E ++ AL + A
Sbjct: 806 VEGCSL-EFAAYSLLYITL---HSNNNR---ELLSSMSRLSEEDKKDEAVRHALSVRAAV 858
Query: 511 IENNYHTFMRIYQQTKGPERHLVNQFIKKERLNALNCMCKA-YARLPLQFLAPELHF 566
NY F R+Y+ L++ +++K R A+N M ++ +P+ ++ L F
Sbjct: 859 TSGNYVMFFRLYKTAPNMNSCLMDLYVEKMRYKAVNFMSRSCRPTIPVSYIVQVLGF 915
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,312,990
Number of Sequences: 60738
Number of extensions: 1484315
Number of successful extensions: 5302
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5279
Number of HSP's gapped (non-prelim): 6
length of query: 622
length of database: 30,389,216
effective HSP length: 112
effective length of query: 510
effective length of database: 23,586,560
effective search space: 12029145600
effective search space used: 12029145600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)