ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2542 good O KOG2778 Posttranslational modification, protein turnover, chaperones Ubiquitin C-terminal hydrolase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2542 888464 887538 -309
(309 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
7294928 [O] KOG2778 Ubiquitin C-terminal hydrolase 169 6e-42
SPBC409.06 [O] KOG2778 Ubiquitin C-terminal hydrolase 166 5e-41
CE01477 [O] KOG2778 Ubiquitin C-terminal hydrolase 165 9e-41
Hs7706753 [O] KOG2778 Ubiquitin C-terminal hydrolase 160 2e-39
At1g65650 [O] KOG2778 Ubiquitin C-terminal hydrolase 150 2e-36
7292743 [O] KOG2778 Ubiquitin C-terminal hydrolase 134 2e-31
Hs4757836 [O] KOG2778 Ubiquitin C-terminal hydrolase 127 3e-29
At5g16310 [O] KOG2778 Ubiquitin C-terminal hydrolase 120 2e-27
7302976 [O] KOG2778 Ubiquitin C-terminal hydrolase 106 4e-23
7295994 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 68 2e-11
CE20818 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 67 3e-11
Hs5174741 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 63 6e-10
CE20817 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 58 2e-08
Hs21361091 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 57 4e-08
HsM4759284 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 56 8e-08
At4g17510 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 54 2e-07
SPAC27F1.03c [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1 52 1e-06
>7294928 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 324
Score = 169 bits (427), Expect = 6e-42
Identities = 109/301 (36%), Positives = 167/301 (55%), Gaps = 32/301 (10%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSL--LKGVVFLFPYEVSLYQ 61
W IESD GVFT LI + G +G Q E+I L+ ES +L + G++FLF + Q
Sbjct: 8 WCLIESDPGVFTELIREFGCDGAQVEEI---WSLDSESFKNLEPIHGLIFLFKW----VQ 60
Query: 62 GSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEFV 121
EP G D + +FF++Q I NACATQA++++L NL D E + LG L+ F EF
Sbjct: 61 EDEPA-GKVVLDRENIFFAKQVINNACATQAILSLLMNL---DHEDIKLGETLTNFKEFC 116
Query: 122 KDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYRSR 181
+ F G T++N+ IR VHNSF P LF +D +N+ K ++V+HFVG++P R
Sbjct: 117 QCFDPYNK-GLTLSNASQIRTVHNSFARPTLFELDT---KNQKKDDDVYHFVGYMPIGGR 172
Query: 182 IYELDGLRPYPIDHGPF---TDFAKDVQNILQERMNILVQLGVHKFNIIGVIKDKLEFLQ 238
+YELDGLR PID G ++ V+ I+++RM +H FN++ +I D+ +
Sbjct: 173 LYELDGLREGPIDLGEIKSEQNWIDVVRPIIEKRMQRYSDGEIH-FNLMALISDRQRIYE 231
Query: 239 NQLQK-----------EDINDSEEFILAEQLQEELNKREKWNEEITFRRHNLTGLVLELA 287
Q++K E+ +E L ++ E+ K++++ E R+HN ++EL
Sbjct: 232 QQIEKLLNPAPNAMDTEEDRQAEISSLRTYIEYEIQKKKRYKVENVRRKHNYLPFIVELL 291
Query: 288 K 288
K
Sbjct: 292 K 292
>SPBC409.06 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 300
Score = 166 bits (419), Expect = 5e-41
Identities = 110/290 (37%), Positives = 166/290 (56%), Gaps = 26/290 (8%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSL--LKGVVFLFPYEVSLYQ 61
W TIESDAGVFT LI +LGV+ ++ ++ L L+ +S+ + G++FLF + +
Sbjct: 3 WTTIESDAGVFTDLIENLGVKDVEVDE---LYSLDVDSLRQFPDIYGIIFLFKWNSKV-- 57
Query: 62 GSEPVQGTYETDS-DKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEF 120
+ GT + DS D +FF++Q I NACATQA++++L N + E + LG LS+F +F
Sbjct: 58 --DKPDGTMDYDSMDNIFFAKQVINNACATQALLSVLLNHSDE----IDLGTTLSEFKDF 111
Query: 121 VKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYRS 180
K EL GE + NSE IR HNSF + F+ +E R +EV+HF+ + +
Sbjct: 112 SKTL-PPELKGEALGNSEHIRCCHNSFARSDPFISEE--VRAATDEDEVYHFIAYTNINN 168
Query: 181 RIYELDGLRPYPIDHGPFT--DFAKDVQNILQERMNILVQLGVHKFNIIGVIKDKLEFLQ 238
YELDGL+ PI+HG T +FA+ +++Q R+ + +FN++ + KDK L
Sbjct: 169 VFYELDGLQAAPINHGSCTKEEFAEKAVSVIQARIANYDPAEI-RFNLMVICKDKKASL- 226
Query: 239 NQLQKEDINDSEEFILAEQLQEELNKREKWNEEITFRRHNLTGLVLELAK 288
L +ED+ D E+ A + E KR +W E RRHN GL +EL+K
Sbjct: 227 --LTREDLTDEEK---AASIAVEDEKRLRWKRENQLRRHNFVGLFVELSK 271
>CE01477 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 326
Score = 165 bits (417), Expect = 9e-41
Identities = 109/294 (37%), Positives = 170/294 (57%), Gaps = 26/294 (8%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPYEVSLYQGS 63
W IESD GVFT ++ GV+GLQ E++ L ++++++ G++FLF + QG
Sbjct: 12 WCLIESDPGVFTEMLRGFGVDGLQVEELYSLD--DDKAMTRPTYGLIFLFKWR----QGD 65
Query: 64 EPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEFVKD 123
E +D +FF+ QTIQNACATQA+IN+L N+ ++ V LG L+Q+ EF D
Sbjct: 66 ETTG--IPSDKQNIFFAHQTIQNACATQALINLLMNV---EDTDVKLGNILNQYKEFAID 120
Query: 124 FHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYRSRIY 183
G ++NSE IR VHNSF+ LF +D G+ E+ +HFV ++P +++Y
Sbjct: 121 L-DPNTRGHCLSNSEEIRTVHNSFSRQTLFELD----IKGGESEDNYHFVTYVPIGNKVY 175
Query: 184 ELDGLRPYPIDHGPF---TDFAKDVQNILQERMNILVQLGVHKFNIIGVI---KDKL-EF 236
ELDGLR P++ F D+ + ++ ++Q+RM + G FN++ ++ K KL E
Sbjct: 176 ELDGLRELPLEVAEFQKEQDWIEAIKPVIQQRMQKYSE-GEITFNLMALVPNRKQKLQEM 234
Query: 237 LQNQLQKEDINDSEEFI--LAEQLQEELNKREKWNEEITFRRHNLTGLVLELAK 288
++N +Q + N+ EE I L + + +E K E + +E RRHN T V+EL K
Sbjct: 235 MENLIQANENNELEEQIADLNKAIADEDYKMEMYRKENNRRRHNYTPFVIELMK 288
>Hs7706753 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 329
Score = 160 bits (406), Expect = 2e-39
Identities = 111/310 (35%), Positives = 170/310 (54%), Gaps = 41/310 (13%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSL--LKGVVFLFPYEVSLYQ 61
W +ESD GVFT LI G G Q E+I LE E+ L + G++FLF ++
Sbjct: 8 WCLMESDPGVFTELIKGFGCRGAQVEEI---WSLEPENFEKLKPVHGLIFLFKWQ----P 60
Query: 62 GSEPVQGTYETDS--DKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYE 119
G EP G+ DS D +FF++Q I NACATQA++++L N +D V LG LS+F E
Sbjct: 61 GEEPA-GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQD---VHLGETLSEFKE 116
Query: 120 FVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYR 179
F + F A + G ++NS++IR VHNSF +F D + K E+ FHFV ++P
Sbjct: 117 FSQSF-DAAMKGLALSNSDVIRQVHNSFARQQMFEFDT---KTSAKEEDAFHFVSYVPVN 172
Query: 180 SRIYELDGLRPYPIDHGPFT--DFAKDVQNILQERMNILVQLGVHKFNIIGVIKD----- 232
R+YELDGLR PID G D+ V+ ++++R+ + G +FN++ ++ D
Sbjct: 173 GRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSE-GEIRFNLMAIVSDRKMIY 231
Query: 233 --KLEFLQNQLQKEDINDSEE---FILAEQ---------LQEELNKREKWNEEITFRRHN 278
K+ LQ QL +E+ D+++ + A Q ++EE+ K +++ E R+HN
Sbjct: 232 EQKIAELQRQLAEEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHN 291
Query: 279 LTGLVLELAK 288
++EL K
Sbjct: 292 YLPFIMELLK 301
>At1g65650 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 330
Score = 150 bits (379), Expect = 2e-36
Identities = 95/248 (38%), Positives = 146/248 (58%), Gaps = 24/248 (9%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSL--LKGVVFLFPYEVSLYQ 61
W TIESD GVFT LI + V+G+Q E+ L L+ +S+++L + G++FLF ++
Sbjct: 3 WCTIESDPGVFTELIQQMQVKGVQVEE---LYSLDSDSLNNLRPVYGLIFLFKWQA---- 55
Query: 62 GSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEFV 121
G + + T + LFF+ Q I NACATQA++ IL N + D +GPELS EF
Sbjct: 56 GEKDERPTIQDQVSNLFFANQVINNACATQAILAILLNSPEVD-----IGPELSALKEFT 110
Query: 122 KDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYRSR 181
K+F ++L G INNS+ IR HNSF P FV +E + K ++V+HF+ +IP
Sbjct: 111 KNF-PSDLKGLAINNSDSIRAAHNSFARPEPFVPEEQ--KAATKDDDVYHFISYIPVDGV 167
Query: 182 IYELDGLRPYPIDHGPF------TDFAKDVQNILQERMNILVQLGVHKFNIIGVIKDKLE 235
+YELDGL+ PI GP ++ + VQ ++QER+ Q + +FN++ VIK++ +
Sbjct: 168 LYELDGLKEGPISLGPCPGDQTGIEWLQMVQPVIQERIERYSQSEI-RFNLLAVIKNRKD 226
Query: 236 FLQNQLQK 243
+L++
Sbjct: 227 IYTAELKE 234
>7292743 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 340
Score = 134 bits (337), Expect = 2e-31
Identities = 98/303 (32%), Positives = 154/303 (50%), Gaps = 33/303 (10%)
Query: 2 SGWNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSL--LKGVVFLFPYEVSL 59
+ W IESD GVFT +I+ G G + E+I ++ ++ L + G++FLF +
Sbjct: 23 NNWCLIESDPGVFTEMISGFGCTGAEVEEI---WSIKADAFRHLEPIHGLIFLFKWL--- 76
Query: 60 YQGSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYE 119
+ G TD +FF++Q I NACATQA++ +L NL ED + LG L+
Sbjct: 77 ---DDKPAGRVVTDRSDIFFARQVIPNACATQALLCLLLNLQHED---IDLGQTLTDLRN 130
Query: 120 FVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYR 179
+D E G + N E IR VHNSF P LFV++E ++ +HFVGF+P +
Sbjct: 131 LCQDL-DPECRGHRLANEEKIRKVHNSFARPELFVVEES---TDFIEDDCYHFVGFMPIK 186
Query: 180 SRIYELDGLRPYPI---DHGPFTDFAKDVQNILQERMNILVQLGVHKFNIIGVIKD---- 232
+++ELDG+ PI D ++ V+ I++ RM +G FN++ ++ D
Sbjct: 187 GKLFELDGMHEGPIELADIDQQQNWLDVVRPIIEARME-RYSVGEIHFNLMALVSDRQRC 245
Query: 233 ---KLEFLQN---QLQKEDINDSEEFILAEQLQEELNKREKWNEEITFRRHNLTGLVLEL 286
K++ L N QL D +E L ++ E K+ ++ +E RRHN ++EL
Sbjct: 246 YERKIQMLVNLPSQLSHAD-RQAEIANLRSHVRHEKEKKRRYRKENIRRRHNYLPFIVEL 304
Query: 287 AKQ 289
KQ
Sbjct: 305 LKQ 307
>Hs4757836 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 729
Score = 127 bits (318), Expect = 3e-29
Identities = 100/315 (31%), Positives = 153/315 (47%), Gaps = 37/315 (11%)
Query: 3 GWNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPY---EVSL 59
GW +ESD G+FT L+ D GV+G+Q E+I LQ + G +FLF + S
Sbjct: 4 GWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQ----SKCQGPVYGFIFLFKWIEERRSR 59
Query: 60 YQGSEPVQGTYETDSD---KLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQ 116
+ S V T D D +FF+ Q I N+CAT A++++L N + SV LGP LS+
Sbjct: 60 RKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCS-----SVDLGPTLSR 114
Query: 117 FYEFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRG----KPEEVFHF 172
+F K F E G I N+ + HNS P + P + G + E FHF
Sbjct: 115 MKDFTKGF-SPESKGYAIGNAPELAKAHNSHARPEPRHL---PEKQNGLSAVRTMEAFHF 170
Query: 173 VGFIPYRSRIYELDGLRPYPIDHGPF---TDFAKDVQNILQERMNILVQLGVH---KFNI 226
V ++P R++ELDGL+ YPIDHGP+ ++ + ++ ER+ + + +FN+
Sbjct: 171 VSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNL 230
Query: 227 IGVIKDKLEFLQNQLQKEDINDSEEFILAEQL----QEELNKREKWNE----EITFRRHN 278
+ V+ D+ + +L +N +QL Q EL + K E E + N
Sbjct: 231 MAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASN 290
Query: 279 LTGLVLELAKQTCSS 293
+ LVLE + +S
Sbjct: 291 KSPLVLEANRAPAAS 305
>At5g16310 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 334
Score = 120 bits (301), Expect = 2e-27
Identities = 74/250 (29%), Positives = 137/250 (54%), Gaps = 22/250 (8%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPYEVSLYQGS 63
W +ESD G+FT +I + V+G+Q E++ L + + + + G++ L+ + +
Sbjct: 3 WLPVESDPGIFTEIIQQMQVKGVQVEELYSLDFNSLDEIRPVY-GLILLYKWRPEEKENR 61
Query: 64 EPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEFVKD 123
+ + FF+ Q I NACATQA++++L N S+ +G ELS+ +F K+
Sbjct: 62 VVIT----EPNPNFFFASQIINNACATQAILSVLMN-----SSSIDIGSELSELKQFAKE 112
Query: 124 FHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPY----RNRGKPEEVFHFVGFIPYR 179
F EL G INN+E IR HN+F P+ + ED +N + ++V+H++ ++P
Sbjct: 113 F-PPELKGLAINNNEAIRAAHNTFARPDPSSIMEDEELAAAKNLDEDDDVYHYISYLPVD 171
Query: 180 SRIYELDGLRPYPIDHGPF------TDFAKDVQNILQERMNILVQLGVHKFNIIGVIKDK 233
+YELDGL+ PI G ++ + VQ ++QE+++ Q + +F+++ V+K++
Sbjct: 172 GILYELDGLKEGPISLGQCLGEPEGIEWLRMVQPVVQEQIDRYSQNEI-RFSLLAVVKNR 230
Query: 234 LEFLQNQLQK 243
E +L++
Sbjct: 231 KEMYVAELKE 240
>7302976 [O] KOG2778 Ubiquitin C-terminal hydrolase
Length = 471
Score = 106 bits (265), Expect = 4e-23
Identities = 82/277 (29%), Positives = 134/277 (47%), Gaps = 24/277 (8%)
Query: 3 GWNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPYEVSLYQG 62
GW +ESD G+FT L+ D G +Q E++ LQ E G +FLF +
Sbjct: 45 GWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQKPIESPY-----GFIFLFRWIEERRAR 99
Query: 63 SEPVQGTYET---DSD---KLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQ 116
+ V+ T E D + +FF+QQ + N+CAT A++++L N +E ++ LG LS+
Sbjct: 100 RKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNC---NENNLQLGDTLSR 156
Query: 117 FYEFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPE---EVFHFV 173
K E G I N+ + HNS P E E FHFV
Sbjct: 157 LKTHTKGM-SPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFV 215
Query: 174 GFIPYRSRIYELDGLRPYPIDHGPF---TDFAKDVQNILQERMNILVQLGVHKFNIIGVI 230
F+P +++ELDGL+PYP++HG + D+ + ++ ER+ I +FN++ V+
Sbjct: 216 SFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVV 275
Query: 231 KDKLEFLQNQLQKEDINDSEEFILAEQLQEELNKREK 267
D+ + ++L+ N + I++ LQ+ L E+
Sbjct: 276 PDRRIAITHKLKMLRTNQA---IVSGTLQKLLKADEQ 309
>7295994 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 227
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/220 (26%), Positives = 92/220 (41%), Gaps = 19/220 (8%)
Query: 1 MSGWNTIESDAGVFTRLITDLGVE-GLQFEDIPYLQYLEEESVSSLLKGVVFLFP----Y 55
M W +ES+ V T+ I LGV D+ L+ E + +K + LFP Y
Sbjct: 1 MLTWTPLESNPEVLTKYIHKLGVSPAWSVTDVIGLEDDTLEWIPRPVKAFILLFPCSETY 60
Query: 56 EVSLYQGSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELS 115
E + + ++ E + LF+ +Q NAC T A+I+ ++A E + G L
Sbjct: 61 EKHRAEEHDRIKEVEEQHPEDLFYMRQFTHNACGTVALIH---SVANNKEVDIDRGV-LK 116
Query: 116 QFYEFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGF 175
F E E G + E FT + + E + + HF+
Sbjct: 117 DFLEKTASLSPEER-GRALEKDE-------KFTADHEALAQEGQTNAANHEKVIHHFIAL 168
Query: 176 IPYRSRIYELDGLRPYPIDHGPFTD--FAKDVQNILQERM 213
+ +YELDG + +PI HGP ++ F KD + +E M
Sbjct: 169 VNKEGTLYELDGRKSFPIKHGPTSEETFVKDAAKVCKEFM 208
>CE20818 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 216
Score = 67.0 bits (162), Expect = 3e-11
Identities = 54/227 (23%), Positives = 100/227 (43%), Gaps = 17/227 (7%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPYEVSLYQGS 63
W +ES+ V +I +GV G++ D+ + ++ES+ V+ FP + +
Sbjct: 5 WTPLESNPSVINPMIEKMGVSGVKTVDV---LFFDDESIGKPQHAVILCFPEYKKVDEIM 61
Query: 64 EPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEFVKD 123
+P+ + D +FF +Q I NAC T A+ + L NL E+ + LG F K
Sbjct: 62 KPIYEQAKAADDSVFFMKQKISNACGTFALFHSLANL----EDRINLGDG-----SFAKW 112
Query: 124 FHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYRSRIY 183
+A+ +G + L N + + + + HF+ F+ +Y
Sbjct: 113 LAEAKKVGIEERSDFLANNAELA----GIHAAAATDGQTAPSGDVEHHFICFVGKNGILY 168
Query: 184 ELDGLRPYPIDHGPFTDFAKDVQNILQERMNILVQLGVHKFNIIGVI 230
E+D RP+ + GP +D A V++ +++ +L F+ I V+
Sbjct: 169 EIDSRRPFAREIGPTSD-ATLVKDAGAACQHLIEKLDNVSFSAIAVV 214
>Hs5174741 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 230
Score = 62.8 bits (151), Expect = 6e-10
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 16/203 (7%)
Query: 4 WNTIESDAGVFTRLITDLGVE-GLQFEDIPYLQYLEEESVSSLLKGVVFLFP----YEVS 58
W +E++ V + + LG+ QF D+ + V + V+ LFP YEV
Sbjct: 6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF 65
Query: 59 LYQGSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFY 118
+ E ++ + + ++F +QTI NAC T +I+ + N +D+ G L +F
Sbjct: 66 RTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIAN--NKDKMHFESGSTLKKFL 123
Query: 119 EFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEV-FHFVGFIP 177
E E + N + IR H + E E+V HF+ +
Sbjct: 124 EESVSMSPEER-ARYLENYDAIRVTHETSA-------HEGQTEAPSIDEKVDLHFIALVH 175
Query: 178 YRSRIYELDGLRPYPIDHGPFTD 200
+YELDG +P+PI+HG +D
Sbjct: 176 VDGHLYELDGRKPFPINHGETSD 198
>CE20817 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 469
Score = 57.8 bits (138), Expect = 2e-08
Identities = 58/236 (24%), Positives = 100/236 (41%), Gaps = 27/236 (11%)
Query: 3 GWNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPYEVS---L 59
GW +ES+ + +G+ GL+ D+ + V + ++ FP + L
Sbjct: 250 GWQALESNPETINPFLKKIGITGLECVDVYSFDDEMLQFVPTPQLALILCFPSAEAREFL 309
Query: 60 YQGSEPVQGTYETDSDKLFFSQ-QTIQNACATQAVINILFNLAKEDEESVTLGPELSQFY 118
+ E V+ E F +Q + I NAC T A+ + L NL E V LG
Sbjct: 310 SKQYEEVEKNGEKPEGVFFMNQSEEIGNACGTFALFHSLANL----ENRVNLGKG----- 360
Query: 119 EFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEV----FHFVG 174
+F K + +A+L+ E S+L+ +L E+ G+ E+ +HF+
Sbjct: 361 KFAKWYEKAKLVNED-ERSDLLSG------DTDLAEAHEET-AEEGETEQSDHVDYHFIT 412
Query: 175 FIPYRSRIYELDGLRPYPIDHGPFTD--FAKDVQNILQERMNILVQLGVHKFNIIG 228
++ ++YE+D P+P G TD KD ++E MN + L ++G
Sbjct: 413 YVNKNGQLYEIDSCAPFPRPLGATTDSTMIKDASTAIKELMNNVKNLSFSAMALVG 468
Score = 49.3 bits (116), Expect = 7e-06
Identities = 50/212 (23%), Positives = 87/212 (40%), Gaps = 37/212 (17%)
Query: 3 GWNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFP-------- 54
GW +ES+ ++ +GV G++ D+ + + + ++ FP
Sbjct: 7 GWQALESNPETINPFLSKIGVSGVECVDVFSFDDEMLQFIPTPQLALILCFPSSGVREFR 66
Query: 55 ---YEVSLYQGSEPVQGTYETDSDKLFFSQQT--IQNACATQAVINILFNLAKEDEESVT 109
YE G +P D +FF Q I +AC T ++ + L NL E V
Sbjct: 67 AKQYEEVEKNGKKP---------DGIFFMNQKKEIGHACGTFSLFHSLANL----ENRVN 113
Query: 110 LGPELSQFYEFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEV 169
LG +F K F +A+L+GE + L+ + + E + PE V
Sbjct: 114 LGNG-----KFSKWFEKAKLVGEGERSDLLLADTDLAEAHKETAEEGETEH-----PEHV 163
Query: 170 -FHFVGFIPYRSRIYELDGLRPYPIDHGPFTD 200
+HF+ ++ +++E+D P+P G TD
Sbjct: 164 AYHFITYVNKNGQLFEIDSCSPFPRPLGATTD 195
>Hs21361091 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 223
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/214 (25%), Positives = 101/214 (46%), Gaps = 25/214 (11%)
Query: 7 IESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLK---GVVFLFP----YEVSL 59
+E + + ++++ LGV G Q+ + L LEEES+ S+ ++ LFP +E
Sbjct: 6 MEINPEMLNKVLSRLGVAG-QWRFVDVLG-LEEESLGSVPAPACALLLLFPLTAQHENFR 63
Query: 60 YQGSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYE 119
+ E ++G + S K++F +QTI N+C T +I+ + N +D+ G L QF
Sbjct: 64 KKQIEELKG--QEVSPKVYFMKQTIGNSCGTIGLIHAVAN--NQDKLGFEDGSVLKQFLS 119
Query: 120 FVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYR 179
+ + + +E I+ H++ +D+ + FHF+ F
Sbjct: 120 ETEKMSPEDR-AKCFEKNEAIQAAHDAVAQEGQCRVDD---------KVNFHFILFNNVD 169
Query: 180 SRIYELDGLRPYPIDHGPFTD--FAKDVQNILQE 211
+YELDG P+P++HG ++ KD + +E
Sbjct: 170 GHLYELDGRMPFPVNHGASSEDTLLKDAAKVCRE 203
>HsM4759284 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 212
Score = 55.8 bits (133), Expect = 8e-08
Identities = 54/208 (25%), Positives = 98/208 (46%), Gaps = 25/208 (12%)
Query: 13 VFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLK---GVVFLFP----YEVSLYQGSEP 65
+ ++++ LGV G Q+ + L LEEES+ S+ ++ LFP +E + E
Sbjct: 1 MLNKVLSRLGVAG-QWRFVDVLG-LEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEE 58
Query: 66 VQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQFYEFVKDFH 125
++G + S K++F +QTI N+C T +I+ + N +D+ G L QF +
Sbjct: 59 LKG--QEVSPKVYFMKQTIGNSCGTIGLIHAVAN--NQDKLGFEDGSVLKQFLSETEKMS 114
Query: 126 QAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFIPYRSRIYEL 185
+ + +E I+ H++ +D+ + FHF+ F +YEL
Sbjct: 115 PEDR-AKCFEKNEAIQAAHDAVAQEGQCRVDD---------KVNFHFILFNNVDGHLYEL 164
Query: 186 DGLRPYPIDHGPFTD--FAKDVQNILQE 211
DG P+P++HG ++ KD + +E
Sbjct: 165 DGRMPFPVNHGASSEDTLLKDAAKVCRE 192
>At4g17510 [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 234
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/237 (23%), Positives = 103/237 (42%), Gaps = 26/237 (10%)
Query: 4 WNTIESDAGVFTRLITDLGV--EGLQFEDIPYLQYLEEESVSSLLKGVVFLFPY-----E 56
W +ES+ V + + LG+ + + D+ L E V + V+FL+P E
Sbjct: 13 WLPLESNPDVMNQYLWGLGLAPDEAECNDVYGLDDELLEMVPKPVLAVLFLYPITKKSEE 72
Query: 57 VSLYQGSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFNLAKEDEESVTLGPELSQ 116
+ Q E + + SDK++F +QT+ NAC T +++ + N+ E + ++ G L +
Sbjct: 73 ERIEQDKEIKEKVH---SDKVYFMKQTVGNACGTIGLLHAIGNITSEIK--LSDGSFLDR 127
Query: 117 FYEFVKDFHQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEVFHFVGFI 176
F++ + E + + N I + H+ + + P + HF+
Sbjct: 128 FFKSTANMTPMER-AKFLENDSQIEDAHSV-----AVIAGDTP----ASEDADTHFICLA 177
Query: 177 PYRSRIYELDGLRPYPIDHGPFT--DFAKDVQNILQERMNILVQLGVHKFNIIGVIK 231
+YELDG + PI HG + KD ++++ I G FN+I + K
Sbjct: 178 CVEGELYELDGRKAGPISHGASSPATLLKDATKVIKKM--IEKNPGSLNFNLIAISK 232
>SPAC27F1.03c [O] KOG1415 Ubiquitin C-terminal hydrolase UCHL1
Length = 222
Score = 52.0 bits (123), Expect = 1e-06
Identities = 56/245 (22%), Positives = 107/245 (42%), Gaps = 46/245 (18%)
Query: 4 WNTIESDAGVFTRLITDLGVEGLQFEDIPYLQYLEEESVSSLLKGVVFLFPYE--VSLYQ 61
W +E+ V + +GV+ D+ L+ + E + + ++F+FP ++Y+
Sbjct: 2 WRPLENTPEVLEPYLQKIGVQDASVFDLFSLEEIPEY-IPRPVHALLFVFPSSGTKTIYK 60
Query: 62 GSEPVQGTYETDSDKLFFSQQTIQNACATQAVINILFN--LAKEDEESVTLGPELSQFYE 119
GS + DSDK+ + QTI NAC T +++ + N L ++ E+ +
Sbjct: 61 GSRILP----KDSDKVLWYPQTIPNACGTIGLLHAVSNGELRRKVNEN-----------D 105
Query: 120 FVKDF------HQAELIGETINNSELIRNVHNSFTPPNLFVMDEDPYRNRGKPEEV---F 170
F+K E + I +S+ + +H +F P P G E+V
Sbjct: 106 FIKSLIRTAEGSSIEERAKLIEDSKELEALHAAFAGP--------PLEVEGSEEDVETDL 157
Query: 171 HFVGFIPYRSR----IYELDGLRPYPIDHGPFTDFAKDVQN--ILQERMNILVQLGVHKF 224
HF+ F+ +S+ YELDG + P+ H ++ D+ N +L N + + F
Sbjct: 158 HFICFVKGKSKDDNHFYELDGRQEGPVQH---SEIESDLLNAEVLSVIKNYIQSIDSPFF 214
Query: 225 NIIGV 229
+++ +
Sbjct: 215 SLVAI 219
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,845,890
Number of Sequences: 60738
Number of extensions: 846109
Number of successful extensions: 2549
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2501
Number of HSP's gapped (non-prelim): 20
length of query: 309
length of database: 30,389,216
effective HSP length: 106
effective length of query: 203
effective length of database: 23,950,988
effective search space: 4862050564
effective search space used: 4862050564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)