ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2619 good O KOG2725 Posttranslational modification, protein turnover, chaperones Cytochrome oxidase assembly factor COX15
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2619 915095 913614 -494
(494 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER141w [O] KOG2725 Cytochrome oxidase assembly factor COX15 571 e-162
SPAC22E12.10c_1 [O] KOG2725 Cytochrome oxidase assembly factor C... 360 3e-99
Hs17921985 [O] KOG2725 Cytochrome oxidase assembly factor COX15 271 1e-72
At5g56090 [O] KOG2725 Cytochrome oxidase assembly factor COX15 265 9e-71
7291690 [O] KOG2725 Cytochrome oxidase assembly factor COX15 257 3e-68
CE02326 [O] KOG2725 Cytochrome oxidase assembly factor COX15 249 9e-66
Hs17921987 [O] KOG2725 Cytochrome oxidase assembly factor COX15 246 6e-65
>YER141w [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 486
Score = 571 bits (1471), Expect = e-162
Identities = 277/403 (68%), Positives = 317/403 (77%)
Query: 91 LNSSKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENEFT 150
L +SK V YWL+GTS LVFGIVVLGGLTRLTESGLSITEW+PV GTLPP+NQ+EWE EF
Sbjct: 80 LKTSKNVAYWLIGTSGLVFGIVVLGGLTRLTESGLSITEWKPVTGTLPPMNQKEWEEEFI 139
Query: 151 KYKSSPEFKQLNSHITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHVNK 210
KYK SPEFK LNSHI LDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAV++KTS HVNK
Sbjct: 140 KYKESPEFKLLNSHIDLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVSKKTSGHVNK 199
Query: 211 RLFGLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGMLWT 270
RLFGL+ LLGLQGF+GWWMVKSGLD+ QL RKSKPTVSQYRLTTHLGTAF LYMGMLWT
Sbjct: 200 RLFGLAGLLGLQGFVGWWMVKSGLDQEQLDARKSKPTVSQYRLTTHLGTAFFLYMGMLWT 259
Query: 271 GFEILREAKWVKNPSEALVLFSKLDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDAGL 330
G EILRE KW+KNP +A+ LF KLDNPA+ P+R+ +L LLA++F+TAMSGG+VAGLDAG
Sbjct: 260 GLEILRECKWIKNPVQAISLFKKLDNPAIGPMRKISLALLAVSFLTAMSGGMVAGLDAGW 319
Query: 331 IYNTFPHMGDDWVPSKRELIDENFARKEDKSDMFWRNMLENPTTVQLNHRILXXXXXXXX 390
+YNT+P MG+ W PS REL+DENF R+EDK D++WRN+LENP TVQL HR
Sbjct: 320 VYNTWPKMGERWFPSSRELMDENFCRREDKKDLWWRNLLENPVTVQLVHRTCAYVAFTSV 379
Query: 391 XXXHMYCNRNKAIIPKQVLRTAHGMMGLATLQVTLGIFTLLYLVPIPLASAHQXXXXXXX 450
HMY + KA+IP+ + + H MMG+ TLQ TLGI T+LYLVPI LAS HQ
Sbjct: 380 LAAHMYAIKKKAVIPRNAMTSLHVMMGVVTLQATLGILTILYLVPISLASIHQAGALALL 439
Query: 451 XXXXXXXXQLRKPRAAIRILTGGLYTQQQKASSKILTEASKLA 493
QLRKPRA +R + L + S KIL+EASKLA
Sbjct: 440 TSSLVFASQLRKPRAPMRNVIITLPHSSKVTSGKILSEASKLA 482
>SPAC22E12.10c_1 [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 472
Score = 360 bits (924), Expect = 3e-99
Identities = 177/356 (49%), Positives = 238/356 (66%), Gaps = 9/356 (2%)
Query: 94 SKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENEFTKYK 153
SK V +WL+G+S LV IVV+GG+TRLTESGLSITEW+P+ G +PPL ++W EF YK
Sbjct: 95 SKKVAFWLLGSSALVLAIVVVGGITRLTESGLSITEWKPITGVIPPLTDEQWNQEFELYK 154
Query: 154 SSPEFKQLNSHITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHVNKRLF 213
SPEF++LNSH+T+DEFK IFF EW HR+ GR IG +LP++Y V ++ SP ++KRL
Sbjct: 155 KSPEFEKLNSHMTVDEFKNIFFWEWFHRVLGRGIGLTILLPSIYMIVTKRASPWLSKRLI 214
Query: 214 GLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGMLWTGFE 273
GL+ L+GLQG IGWWMVKSGL E +L S P VS YRL THL A LY+G++WTG
Sbjct: 215 GLTGLVGLQGVIGWWMVKSGLSE-ELFSDGSHPRVSHYRLATHLAAAVALYIGLVWTGHG 273
Query: 274 ILREAKWVK-----NPSEALVLFSKLDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDA 328
IL+ ++K + S+ + S + + R S + L +T +SG VAGLDA
Sbjct: 274 ILQRHAFLKSMKSGSTSQLTSMVSSVQK--MKGFRTSVNSFVGLVLITLLSGAFVAGLDA 331
Query: 329 GLIYNTFPHMGDD-WVPSKRELIDENFARKEDKSDMFWRNMLENPTTVQLNHRILXXXXX 387
G+IY TFP MG+ PSK EL D+ F RK+DKSD+ WRNM++NP+ VQL HRIL
Sbjct: 332 GMIYCTFPEMGEGRLAPSKSELFDQRFCRKDDKSDLIWRNMIDNPSLVQLEHRILAITTF 391
Query: 388 XXXXXXHMYCNRNKAIIPKQVLRTAHGMMGLATLQVTLGIFTLLYLVPIPLASAHQ 443
++ + I+PK++ + + + G+ T Q TLGI TL+Y+VP+PLA+ HQ
Sbjct: 392 VAACGLFIFSRAKRNILPKKIKTSINVVTGVVTAQATLGIMTLIYVVPVPLAALHQ 447
>Hs17921985 [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 410
Score = 271 bits (694), Expect = 1e-72
Identities = 158/379 (41%), Positives = 207/379 (53%), Gaps = 37/379 (9%)
Query: 89 PLLNSSKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENE 148
P + +VVG WL+ S V G V+LGG+TRLTESGLS+ +W + PP +Q+EWE E
Sbjct: 61 PSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAE 120
Query: 149 FTKYKSSPEFKQLNSHITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHV 208
F +Y+ PEFK LN +TL EFKFI++ME+ HR+WGR +G V+ILPA YF S +
Sbjct: 121 FQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGM 180
Query: 209 NKRLFGLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGML 268
R+ L L+ QG +GW+MVKSGL+E + P VSQYRL HLG+A +LY L
Sbjct: 181 KGRVLALCGLVCFQGLLGWYMVKSGLEEK--SDSHDIPRVSQYRLAAHLGSALVLYCASL 238
Query: 269 WTGFEILREAKWVKNPSEALVLFSKLDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDA 328
WT +L P L + L LRR A G L F+TA+SG VAGLDA
Sbjct: 239 WTSLSLLL-------PPHKLP-----ETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDA 286
Query: 329 GLIYNTFPHMGDDWVPSKRELIDENFARKEDKSDMF-----WRNMLENPTTVQLNHRILX 383
GL+YN+FP MG+ W+P D+F RN+ ENPT VQ +HRIL
Sbjct: 287 GLVYNSFPKMGESWIP----------------EDLFTFSPILRNVFENPTMVQFDHRILG 330
Query: 384 XXXXXXXXXXHMYCNRNKAIIPKQVLRTAHGMMGLATLQVTLGIFTLLYLVPIPLASAHQ 443
+Y + +P++ A ++ LA QV LGI TLL VP PLA+ HQ
Sbjct: 331 ITSVTAITV--LYFLSRRIPLPRRTKMAAVTLLALAYTQVGLGISTLLMYVPTPLAATHQ 388
Query: 444 XXXXXXXXXXXXXXXQLRK 462
+LR+
Sbjct: 389 SGSLALLTGALWLMNELRR 407
>At5g56090 [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 457
Score = 265 bits (678), Expect = 9e-71
Identities = 152/375 (40%), Positives = 207/375 (54%), Gaps = 25/375 (6%)
Query: 93 SSKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENEFTKY 152
+ K VG WL G++ VF +VVLGG+TRLT SGLS+T+W+ G PPL+ + W EF KY
Sbjct: 95 AQKWVGIWLFGSAAWVFSMVVLGGVTRLTRSGLSMTDWK-FTGEFPPLSDEAWAKEFEKY 153
Query: 153 KSSPEFKQLNSHITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHVNKRL 212
K SPE+K++N + L++FKFI++ME+ HR+WGR +G +F LP YF + + +L
Sbjct: 154 KQSPEYKRVNKGMNLEDFKFIYWMEYAHRMWGRGLGIMFALPFSYFLRKGYITLRLGVQL 213
Query: 213 FGLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGMLWTGF 272
GL AL QGFIGWWMVKSGL+E S+P VS YRL HL +AF +Y G+ WT
Sbjct: 214 SGLFALGAGQGFIGWWMVKSGLEEP--PSEYSQPRVSPYRLAAHLTSAFAIYCGLFWTAL 271
Query: 273 EILREAKWVKNPSEALVLFSKLDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDAGLIY 332
++ + P+E+L A +++ AL + + +TA+SG VAG DAG +
Sbjct: 272 SVVMP----EPPAESLAWVR-----GAAKVKKLALPVSLIVGITAISGAFVAGNDAGRAF 322
Query: 333 NTFPHMGDDWVPSKRELIDENFARKEDKSDMFWRNMLENPTTVQLNHRILXXXXXXXXXX 392
NTFP MGD W+P D F K RN EN TVQL+HR+L
Sbjct: 323 NTFPKMGDTWIP------DNIFEMKP-----LLRNFFENTATVQLDHRLLATTTLIAIGT 371
Query: 393 XHMYCNRNKAIIPKQVLRTAHGMMGLATLQVTLGIFTLLYLVPIPLASAHQXXXXXXXXX 452
M+ K I V +G+ +QVTLG+ TLL VP+ L SAHQ
Sbjct: 372 --MWWFTRKLDIHPAVKALIGSTVGMTAVQVTLGVSTLLSYVPVSLGSAHQAGALTLLTL 429
Query: 453 XXXXXXQLRKPRAAI 467
LR+P ++
Sbjct: 430 MLLLNHTLRRPSPSL 444
>7291690 [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 393
Score = 257 bits (656), Expect = 3e-68
Identities = 151/353 (42%), Positives = 203/353 (56%), Gaps = 30/353 (8%)
Query: 93 SSKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENEFTKY 152
S K VG W +G S +VF V LGG+TRLTESGLS+ W+ + G P Q+EW EF Y
Sbjct: 44 SDKTVGRWFLGVSGMVFVAVGLGGVTRLTESGLSMVTWK-LTGERMPRTQEEWVQEFNLY 102
Query: 153 KSSPEFKQLNSHITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHVNKRL 212
+ PE+K N ++T++EFKFIF ME++HR+WGRAIG F+LPAVYF K +
Sbjct: 103 QQYPEYKLKNVNMTVEEFKFIFMMEYMHRMWGRAIGGFFLLPAVYFWRKGYFCAKTKKSV 162
Query: 213 FGLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGMLWTGF 272
L L+GLQG +GW+MVKSGL E + ++ P VSQYRL +HL AF+LY L
Sbjct: 163 LLLGTLIGLQGLMGWYMVKSGL-EDRFQDPNDVPRVSQYRLASHLAAAFVLYSLSLSKAM 221
Query: 273 EILREAKWVKNPSEALVLFSK--LDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDAGL 330
+L P+ V+ +K + L L + A+ +TA+SG VAGLDAGL
Sbjct: 222 SLL-------IPTNTFVIQAKKAFNIKGLTHLTK------AMVLLTAISGAFVAGLDAGL 268
Query: 331 IYNTFPHMGDDWVPSKRELIDENFARKEDKSDMFWRNMLENPTTVQLNHRILXXXXXXXX 390
+YN+FP MGD W+P FA + +N+ ENPTTVQ NHRIL
Sbjct: 269 VYNSFPKMGDKWIPDDM----WTFAPIQ-------KNITENPTTVQFNHRILGISTVTLT 317
Query: 391 XXXHMYCNRNKAIIPKQVLRTAHGMMGLATLQVTLGIFTLLYLVPIPLASAHQ 443
+ R + +PK+ + ++ +A Q TLG+ TLL VP+PLA+AHQ
Sbjct: 318 TALWLVTRRMQ--LPKRANWAINAVVAMAWTQATLGVTTLLNYVPVPLATAHQ 368
>CE02326 [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 395
Score = 249 bits (635), Expect = 9e-66
Identities = 147/372 (39%), Positives = 197/372 (52%), Gaps = 28/372 (7%)
Query: 93 SSKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENEFTKY 152
S K +G+WL+G + + +G V LGG+TRLTESGLS+ W PP Q++WE EF KY
Sbjct: 47 SRKRIGWWLMGCAGMCYGAVALGGVTRLTESGLSMVNWDLFRTMKPPFGQKQWEEEFEKY 106
Query: 153 KSSPEFKQLNS--HITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHVNK 210
K+ PE+K +S +TL+EFKFI+ ME+ HR+WGRAIG VF++P YF + +P + +
Sbjct: 107 KAYPEYKYKSSSEEMTLNEFKFIWSMEYGHRMWGRAIGIVFLIPCAYFWARGRFAPDMKR 166
Query: 211 RLFGLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGMLWT 270
R+ + LL QG IGWWMVKSGLD + K P VSQYRL THL AF+LY W
Sbjct: 167 RMALATTLLLAQGGIGWWMVKSGLDPS--KNSSDVPRVSQYRLATHLTMAFVLYSIFFWN 224
Query: 271 GFEILREAKWVKNPSEALVLFSKLDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDAGL 330
G L P + + SK L LR G + F TA+ G VAGLDAGL
Sbjct: 225 GLSHL------VKPHDLSKVRSK-----LGALRGMTHGSKLMVFSTAIMGAFVAGLDAGL 273
Query: 331 IYNTFPHMGDDWVPSKRELIDENFARKEDKSDMFWRNMLENPTTVQLNHRILXXXXXXXX 390
+YN++P ++W+P EN + W+N EN TVQ HR L
Sbjct: 274 VYNSWPKFAENWIP-------ENMLSRSPT----WKNFFENDVTVQFVHRNLAYLTVISV 322
Query: 391 XXXHMYCNRNKAIIPKQVLRTAHGMMGLATLQVTLGIFTLLYLVPIPLASAHQXXXXXXX 450
+ R A IPK+ + + Q LG+FTL+ VP+ LA+ HQ
Sbjct: 323 LSTFLIGRR--APIPKRTRMALNLTVAAVFGQAALGVFTLINYVPVWLAACHQSGSMALL 380
Query: 451 XXXXXXXXQLRK 462
+LR+
Sbjct: 381 SSVLWLSHELRR 392
>Hs17921987 [O] KOG2725 Cytochrome oxidase assembly factor COX15
Length = 388
Score = 246 bits (628), Expect = 6e-65
Identities = 142/339 (41%), Positives = 188/339 (54%), Gaps = 37/339 (10%)
Query: 89 PLLNSSKVVGYWLVGTSILVFGIVVLGGLTRLTESGLSITEWRPVAGTLPPLNQQEWENE 148
P + +VVG WL+ S V G V+LGG+TRLTESGLS+ +W + PP +Q+EWE E
Sbjct: 61 PSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAE 120
Query: 149 FTKYKSSPEFKQLNSHITLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVARKTSPHV 208
F +Y+ PEFK LN +TL EFKFI++ME+ HR+WGR +G V+ILPA YF S +
Sbjct: 121 FQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGM 180
Query: 209 NKRLFGLSALLGLQGFIGWWMVKSGLDETQLKERKSKPTVSQYRLTTHLGTAFMLYMGML 268
R+ L L+ QG +GW+MVKSGL+E + P VSQYRL HLG+A +LY L
Sbjct: 181 KGRVLALCGLVCFQGLLGWYMVKSGLEEK--SDSHDIPRVSQYRLAAHLGSALVLYCASL 238
Query: 269 WTGFEILREAKWVKNPSEALVLFSKLDNPALAPLRRSALGLLALTFVTAMSGGLVAGLDA 328
WT +L P L + L LRR A G L F+TA+SG VAGLDA
Sbjct: 239 WTSLSLLL-------PPHKLP-----ETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDA 286
Query: 329 GLIYNTFPHMGDDWVPSKRELIDENFARKEDKSDMF-----WRNMLENPTTVQLNHRILX 383
GL+YN+FP MG+ W+P D+F RN+ ENPT VQ +HRIL
Sbjct: 287 GLVYNSFPKMGESWIP----------------EDLFTFSPILRNVFENPTMVQFDHRILG 330
Query: 384 XXXXXXXXXXHMYCNRNKAIIPKQVLRTAHGMMGLATLQ 422
+Y + +P++ A ++ LA Q
Sbjct: 331 ITSVTAITV--LYFLSRRIPLPRRTKMAAVTLLALAYTQ 367
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,046,414
Number of Sequences: 60738
Number of extensions: 913831
Number of successful extensions: 1890
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1851
Number of HSP's gapped (non-prelim): 8
length of query: 494
length of database: 30,389,216
effective HSP length: 110
effective length of query: 384
effective length of database: 23,708,036
effective search space: 9103885824
effective search space used: 9103885824
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)