ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2664 check: MH T KOG0660 Signal transduction mechanisms Mitogen-activated protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2664 929989 931101 371
(371 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL016w [T] KOG0660 Mitogen-activated protein kinase 524 e-148
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 393 e-109
YGR040w [T] KOG0660 Mitogen-activated protein kinase 373 e-103
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 350 2e-96
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 350 2e-96
CE24971 [T] KOG0660 Mitogen-activated protein kinase 336 3e-92
CE01583 [T] KOG0660 Mitogen-activated protein kinase 336 3e-92
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 335 6e-92
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 334 1e-91
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 327 2e-89
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 323 3e-88
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 320 2e-87
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 312 6e-85
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 309 4e-84
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 307 2e-83
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 305 5e-83
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 303 3e-82
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 302 5e-82
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 302 5e-82
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 301 8e-82
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 301 1e-81
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 295 7e-80
7298087 [T] KOG0660 Mitogen-activated protein kinase 295 1e-79
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 294 2e-79
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 290 2e-78
YHR030c [T] KOG0660 Mitogen-activated protein kinase 289 4e-78
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 285 8e-77
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 280 2e-75
YLR113w [T] KOG0660 Mitogen-activated protein kinase 279 4e-75
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 278 7e-75
7301110 [T] KOG0660 Mitogen-activated protein kinase 278 1e-74
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 277 2e-74
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 275 8e-74
CE06686 [T] KOG0660 Mitogen-activated protein kinase 273 4e-73
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 270 2e-72
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 270 3e-72
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 269 6e-72
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 263 2e-70
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 260 3e-69
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 259 4e-69
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 245 7e-65
CE17062 [T] KOG0660 Mitogen-activated protein kinase 244 1e-64
YKL161c [T] KOG0660 Mitogen-activated protein kinase 243 3e-64
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 239 6e-63
CE06762 [T] KOG0660 Mitogen-activated protein kinase 235 7e-62
CE29020 [T] KOG0660 Mitogen-activated protein kinase 231 2e-60
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 228 8e-60
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 228 1e-59
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 227 2e-59
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 223 3e-58
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 223 3e-58
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 223 3e-58
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 223 3e-58
YPR054w [T] KOG0660 Mitogen-activated protein kinase 221 1e-57
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 221 2e-57
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 221 2e-57
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 214 2e-55
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 214 2e-55
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 214 2e-55
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 212 8e-55
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 212 8e-55
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 212 8e-55
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 211 2e-54
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 211 2e-54
CE29318 [T] KOG0660 Mitogen-activated protein kinase 209 5e-54
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 208 1e-53
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 208 1e-53
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 205 1e-52
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 204 2e-52
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 202 6e-52
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 201 1e-51
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 199 4e-51
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 196 4e-50
7291043 [T] KOG0660 Mitogen-activated protein kinase 194 2e-49
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 192 9e-49
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 190 3e-48
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 189 7e-48
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 188 1e-47
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 187 2e-47
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 185 1e-46
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 185 1e-46
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 184 2e-46
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 183 3e-46
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 182 5e-46
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 182 9e-46
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 182 9e-46
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 182 9e-46
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 182 9e-46
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 182 9e-46
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 181 1e-45
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 181 2e-45
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 180 3e-45
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 180 3e-45
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 179 6e-45
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 179 6e-45
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 178 1e-44
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 176 4e-44
CE27220 [T] KOG0660 Mitogen-activated protein kinase 176 5e-44
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 175 8e-44
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 174 1e-43
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 174 1e-43
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 174 2e-43
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 174 2e-43
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 173 3e-43
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 173 4e-43
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 172 5e-43
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 172 5e-43
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 172 5e-43
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 172 7e-43
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 172 7e-43
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 172 9e-43
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 172 9e-43
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 172 9e-43
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 171 1e-42
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 171 2e-42
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 171 2e-42
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 171 2e-42
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 170 4e-42
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 169 6e-42
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 169 6e-42
At5g10270 [D] KOG0600 Cdc2-related protein kinase 169 8e-42
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 168 1e-41
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 168 1e-41
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 168 1e-41
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 2e-41
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 3e-41
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 3e-41
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 167 3e-41
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 167 3e-41
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 166 4e-41
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 166 4e-41
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 166 4e-41
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 166 5e-41
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 166 5e-41
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 165 9e-41
At5g64960 [D] KOG0600 Cdc2-related protein kinase 165 9e-41
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 164 1e-40
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 164 2e-40
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 164 2e-40
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 164 2e-40
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 164 2e-40
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 164 3e-40
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 164 3e-40
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 163 3e-40
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 163 3e-40
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 163 3e-40
CE21401 [G] KOG0658 Glycogen synthase kinase-3 162 7e-40
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 162 1e-39
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 161 2e-39
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 160 3e-39
7296451 [D] KOG0600 Cdc2-related protein kinase 160 3e-39
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 159 5e-39
CE26422 [D] KOG0600 Cdc2-related protein kinase 159 8e-39
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 159 8e-39
7290342 [G] KOG0658 Glycogen synthase kinase-3 157 2e-38
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 156 5e-38
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 155 7e-38
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 154 2e-37
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 154 3e-37
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 153 3e-37
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 153 4e-37
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 153 4e-37
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 153 4e-37
YPR161c [D] KOG0600 Cdc2-related protein kinase 152 8e-37
YKL139w [D] KOG0600 Cdc2-related protein kinase 152 8e-37
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 152 8e-37
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 151 1e-36
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 2e-36
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 2e-36
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 151 2e-36
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 2e-36
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 150 2e-36
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 150 2e-36
YMR139w [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 150 4e-36
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 150 4e-36
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 1e-35
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 1e-35
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 148 1e-35
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 148 1e-35
At1g33770 [D] KOG0600 Cdc2-related protein kinase 148 1e-35
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 147 2e-35
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 147 2e-35
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 146 4e-35
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 145 7e-35
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 145 7e-35
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 145 1e-34
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 144 3e-34
At5g50860 [D] KOG0600 Cdc2-related protein kinase 143 4e-34
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 143 5e-34
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 142 1e-33
At3g05050 [D] KOG0600 Cdc2-related protein kinase 140 2e-33
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 140 2e-33
At1g71530 [D] KOG0600 Cdc2-related protein kinase 140 4e-33
At1g03740 [D] KOG0600 Cdc2-related protein kinase 139 5e-33
At4g22940 [D] KOG0600 Cdc2-related protein kinase 139 7e-33
CE08727 [G] KOG0658 Glycogen synthase kinase-3 139 9e-33
At1g54610 [D] KOG0600 Cdc2-related protein kinase 138 1e-32
At1g57700 [D] KOG0600 Cdc2-related protein kinase 138 1e-32
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 137 2e-32
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 136 6e-32
At1g53050 [D] KOG0600 Cdc2-related protein kinase 136 6e-32
At5g44290 [D] KOG0600 Cdc2-related protein kinase 134 3e-31
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 133 4e-31
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 133 4e-31
At5g39420 [D] KOG0600 Cdc2-related protein kinase 133 4e-31
At4g10010 [D] KOG0600 Cdc2-related protein kinase 133 5e-31
At1g18670 [D] KOG0600 Cdc2-related protein kinase 131 1e-30
At1g09600 [D] KOG0600 Cdc2-related protein kinase 131 1e-30
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 131 2e-30
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 129 5e-30
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 129 5e-30
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 129 5e-30
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 129 7e-30
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 128 1e-29
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 128 2e-29
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 127 2e-29
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 127 3e-29
At1g74330 [D] KOG0600 Cdc2-related protein kinase 127 3e-29
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 126 4e-29
YDL079c [G] KOG0658 Glycogen synthase kinase-3 126 6e-29
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 125 1e-28
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 124 3e-28
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 123 4e-28
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 121 2e-27
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 120 4e-27
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 120 4e-27
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 119 7e-27
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 119 7e-27
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 119 7e-27
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 119 9e-27
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 117 2e-26
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 117 2e-26
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 117 3e-26
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 117 4e-26
Hs18581346 [T] KOG0660 Mitogen-activated protein kinase 116 5e-26
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 116 5e-26
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 116 5e-26
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 116 5e-26
YNL307c [G] KOG0658 Glycogen synthase kinase-3 116 6e-26
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 115 8e-26
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 115 1e-25
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 115 1e-25
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 114 2e-25
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 114 2e-25
At3g01090 [T] KOG0583 Serine/threonine protein kinase 114 3e-25
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 112 7e-25
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 112 7e-25
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 112 7e-25
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 112 9e-25
At5g39440 [T] KOG0583 Serine/threonine protein kinase 112 9e-25
At3g29160 [T] KOG0583 Serine/threonine protein kinase 111 1e-24
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 110 4e-24
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 109 6e-24
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 109 6e-24
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 2e-23
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 107 3e-23
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 107 4e-23
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 4e-23
CE09532 [G] KOG0658 Glycogen synthase kinase-3 106 6e-23
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 105 1e-22
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 105 1e-22
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 104 2e-22
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 104 2e-22
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 104 2e-22
CE05866 [G] KOG0658 Glycogen synthase kinase-3 104 2e-22
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 103 3e-22
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 3e-22
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 103 4e-22
7298004 [G] KOG0658 Glycogen synthase kinase-3 102 7e-22
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 102 9e-22
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 102 1e-21
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 101 2e-21
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 100 3e-21
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 3e-21
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 100 3e-21
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 3e-21
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 3e-21
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 100 3e-21
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 4e-21
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 100 6e-21
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 99 8e-21
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 99 8e-21
At5g45810 [T] KOG0583 Serine/threonine protein kinase 99 8e-21
YDR477w [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 1e-20
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 98 2e-20
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 98 2e-20
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 2e-20
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 97 4e-20
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 5e-20
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 8e-20
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 96 8e-20
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 96 1e-19
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 95 1e-19
At4g32830 [D] KOG0580 Serine/threonine protein kinase 95 1e-19
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 1e-19
At2g25880 [D] KOG0580 Serine/threonine protein kinase 95 1e-19
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 95 2e-19
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 95 2e-19
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 94 2e-19
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 94 3e-19
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 94 3e-19
At5g25110 [T] KOG0583 Serine/threonine protein kinase 94 3e-19
At4g18700 [T] KOG0583 Serine/threonine protein kinase 94 3e-19
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 94 4e-19
At5g10930 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 94 4e-19
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 93 5e-19
At5g01810 [T] KOG0583 Serine/threonine protein kinase 93 5e-19
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 93 5e-19
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 93 5e-19
At1g29230 [T] KOG0583 Serine/threonine protein kinase 93 7e-19
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 92 9e-19
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 92 1e-18
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 1e-18
At2g30360 [T] KOG0583 Serine/threonine protein kinase 92 1e-18
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 92 1e-18
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 92 2e-18
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 92 2e-18
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 3e-18
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 91 3e-18
YPL209c [D] KOG0580 Serine/threonine protein kinase 90 5e-18
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 90 5e-18
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 90 5e-18
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 90 5e-18
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 90 5e-18
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 90 5e-18
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 90 6e-18
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 90 6e-18
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 90 6e-18
CE18454 [T] KOG4717 Serine/threonine protein kinase 90 6e-18
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 90 6e-18
Hs8923539 [R] KOG0597 Serine-threonine protein kinase FUSED 89 8e-18
ECU10g0120 [L] KOG1167 Serine/threonine protein kinase of the CD... 89 8e-18
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 8e-18
At2g38490 [T] KOG0583 Serine/threonine protein kinase 89 8e-18
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 89 1e-17
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 89 1e-17
ECU08g1960 [L] KOG1167 Serine/threonine protein kinase of the CD... 89 1e-17
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 89 1e-17
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 89 1e-17
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 89 1e-17
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 89 1e-17
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 89 1e-17
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 88 2e-17
CE20405 [G] KOG0658 Glycogen synthase kinase-3 88 2e-17
At5g07070 [T] KOG0583 Serine/threonine protein kinase 88 2e-17
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 88 2e-17
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 88 2e-17
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 2e-17
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 88 2e-17
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 87 3e-17
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 87 3e-17
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 87 3e-17
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 87 4e-17
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 87 4e-17
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 87 4e-17
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 87 4e-17
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 87 4e-17
At4g30960 [T] KOG0583 Serine/threonine protein kinase 87 4e-17
At2g34180 [T] KOG0583 Serine/threonine protein kinase 87 4e-17
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 87 5e-17
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 87 5e-17
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 5e-17
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 87 5e-17
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 86 7e-17
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 7e-17
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 86 7e-17
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 86 7e-17
SPBC409.07c [T] KOG0581 Mitogen-activated protein kinase kinase ... 86 9e-17
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 86 9e-17
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 86 9e-17
At1g30270 [T] KOG0583 Serine/threonine protein kinase 86 9e-17
7302464 [R] KOG0586 Serine/threonine protein kinase 86 9e-17
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 86 1e-16
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 86 1e-16
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 86 1e-16
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 86 1e-16
CE25437 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 86 1e-16
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 86 1e-16
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 1e-16
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 85 1e-16
Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 85 1e-16
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 85 1e-16
At5g45820 [T] KOG0583 Serine/threonine protein kinase 85 1e-16
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 85 1e-16
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 85 2e-16
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 85 2e-16
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 85 2e-16
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 85 2e-16
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 85 2e-16
CE24761 [D] KOG0580 Serine/threonine protein kinase 85 2e-16
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 85 2e-16
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 85 2e-16
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 85 2e-16
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 84 3e-16
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 84 3e-16
At2g26980 [T] KOG0583 Serine/threonine protein kinase 84 3e-16
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 84 3e-16
Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 84 3e-16
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 84 3e-16
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 84 3e-16
At1g01140 [T] KOG0583 Serine/threonine protein kinase 84 3e-16
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
CE28218 [D] KOG0588 Serine/threonine protein kinase 84 4e-16
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 84 4e-16
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 84 4e-16
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 84 4e-16
At5g35410 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
At5g01820 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 84 4e-16
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 83 6e-16
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 83 6e-16
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 83 6e-16
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 83 6e-16
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 83 7e-16
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 83 7e-16
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 83 7e-16
CE15235 [R] KOG0589 Serine/threonine protein kinase 83 7e-16
At4g24400 [T] KOG0583 Serine/threonine protein kinase 83 7e-16
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 82 1e-15
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 82 1e-15
CE27768 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
CE23838 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 82 1e-15
CE04586 [T] KOG1989 ARK protein kinase family 82 1e-15
At5g58380 [T] KOG0583 Serine/threonine protein kinase 82 1e-15
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 82 1e-15
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 1e-15
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 82 1e-15
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 82 2e-15
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 82 2e-15
CE23001 [R] KOG0589 Serine/threonine protein kinase 82 2e-15
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 82 2e-15
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 82 2e-15
At3g17510 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 81 2e-15
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 81 2e-15
Hs21618351 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 81 2e-15
Hs21618349 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 81 2e-15
Hs21618347 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 81 2e-15
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 81 2e-15
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 81 2e-15
CE05549 [T] KOG0671 LAMMER dual specificity kinases 81 2e-15
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 81 2e-15
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 81 2e-15
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 81 2e-15
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 80 4e-15
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 80 4e-15
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 80 4e-15
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 80 4e-15
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 80 4e-15
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 80 4e-15
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 80 4e-15
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 80 4e-15
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 80 4e-15
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 80 5e-15
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 80 5e-15
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 80 5e-15
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 80 5e-15
7290150 [T] KOG0583 Serine/threonine protein kinase 80 5e-15
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 80 6e-15
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 80 6e-15
At4g40010 [T] KOG0583 Serine/threonine protein kinase 80 6e-15
At3g23000 [T] KOG0583 Serine/threonine protein kinase 80 6e-15
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 79 8e-15
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 79 8e-15
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 79 8e-15
7299438 [R] KOG0586 Serine/threonine protein kinase 79 8e-15
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 79 8e-15
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 79 1e-14
At4g33950 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
At4g14580 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 79 1e-14
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 524 bits (1349), Expect = e-148
Identities = 256/373 (68%), Positives = 302/373 (80%), Gaps = 22/373 (5%)
Query: 1 MGKRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREI 60
M KRIV+NISS+FQL+SLLGEGAYGVVCSA HKP+GEIVAIKKIEPF+KPLF++RTLREI
Sbjct: 1 MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREI 60
Query: 61 KILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQ 120
KILKHF+HENII+IF++Q+P SFE FNEVYIIQELMQTDLHRVI TQ LS+DH+QYF+YQ
Sbjct: 61 KILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQ 120
Query: 121 TLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXX 180
TLRA+KVLHGSNVIHRDLKPSNLL+NSNCDLK+CDFGLARI+ E
Sbjct: 121 TLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDE---------------- 164
Query: 181 NSPSSAANDGDPA--ISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
SAA++ +P SGMTEYVATRWYRAPEVMLT+A+YS++MDVWSCGCILAEL ++
Sbjct: 165 ----SAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRR 220
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA 298
P+FPG+DYR QL+LIF +GTP + +E+ RAREYI+SLP +P + FP +
Sbjct: 221 PIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNP 280
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNT 358
+DLL RML FDP RITA EAL HPYL +YHDP+DEPEG PIP SFF+FD +K L T
Sbjct: 281 KGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHYKEALTT 340
Query: 359 KDLKRLLWNEIVS 371
KDLK+L+WNEI S
Sbjct: 341 KDLKKLIWNEIFS 353
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 393 bits (1010), Expect = e-109
Identities = 193/363 (53%), Positives = 256/363 (70%), Gaps = 26/363 (7%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF 66
F + E+++ +L+G+GAYGVVC+A HKPSG VA+KKI PF P+F +RTLREIK+L+HF
Sbjct: 33 FELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHF 92
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALK 126
+HENIISI D+ P S+++ +VYI+QELM+TDL+RVI +Q LS+DH QYF YQ LRALK
Sbjct: 93 RHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQPLSDDHCQYFTYQILRALK 152
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
+H + V+HRDLKPSNLLLN+NCDLK+ DFGLAR S+
Sbjct: 153 AMHSAGVVHRDLKPSNLLLNANCDLKVADFGLAR-----------------------STT 189
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
A G+P MTEYVATRWYRAPE+ML+ +YSK++D+WS GCILAE+L +PLFPGKDY
Sbjct: 190 AQGGNPGF--MTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDY 247
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
Q+ LI LGTPT + +++ RAR+YI+SLP PK++++ FP AS A+DLL++
Sbjct: 248 HSQITLILNILGTPTMDDF-SRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEK 306
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
+L F+P RITA EAL HPY+ +YHD DEP +P+P + K L LK L++
Sbjct: 307 LLTFNPDKRITAEEALKHPYVAAYHDASDEPTASPMPPNLVDLYCNKEDLEIPVLKALIF 366
Query: 367 NEI 369
E+
Sbjct: 367 REV 369
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 373 bits (958), Expect = e-103
Identities = 194/386 (50%), Positives = 264/386 (68%), Gaps = 38/386 (9%)
Query: 1 MGKRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREI 60
M + I F+I S+++L L+GEGAYG VCSA HKPSG VAIKKI+PF K LF RT+REI
Sbjct: 1 MARTITFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREI 60
Query: 61 KILKHF-QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE-----LSEDHV 114
K+L++F +HENIISI D +P S ++ N VY+++ELM+TDL +VI Q LS+DHV
Sbjct: 61 KLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHV 120
Query: 115 QYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXX 174
QYF YQ LRALK +H + VIHRD+KPSNLLLNSNCDLK+CDFGLAR ++
Sbjct: 121 QYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLA----------- 169
Query: 175 XXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAEL 234
S+++ + + MTEYVATRWYRAPE+MLT +Y+ +MD+WSCGCILAE+
Sbjct: 170 ----------SSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEM 219
Query: 235 LGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF- 293
+ +PLFPG+DY QL LI + LGTP+ ++ + ++++RA+EYI +LP P + W +
Sbjct: 220 VSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQ-IKSKRAKEYIANLPMRPPLPWETVWS 278
Query: 294 -PNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTP--IPSSFFQFD 350
+ + +DLLD+MLQF+P RI+A EAL HPYL YHDP DEPE P + F++ D
Sbjct: 279 KTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYPPLNLDDEFWKLD 338
Query: 351 QWKSRLNTKD------LKRLLWNEIV 370
R ++ LK +L++E++
Sbjct: 339 NKIMRPEEEEEVPIEMLKDMLYDELM 364
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 350 bits (898), Expect = 2e-96
Identities = 183/364 (50%), Positives = 239/364 (65%), Gaps = 32/364 (8%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKH 65
VF++ + S +GEGAYG+VCSA + VAIKKI PFE + RTLREIKIL
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLR 77
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRAL 125
F+HENII I D+ + + EQ +VYI+Q+LM+TDL++++ TQ LS DH+ YF+YQ LR L
Sbjct: 78 FRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGL 137
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
K +H +NV+HRDLKPSNLLLN+ CDLKICDFGLAR+
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVA----------------------- 174
Query: 186 AANDGDPAISG-MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
D D +G +TEYVATRWYRAPE+ML + Y+KS+D+WS GCILAE+L +P+FPGK
Sbjct: 175 ---DPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGK 231
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
Y DQL I LG+P++++L + N +AR Y+ SLP K+ W R FPNA + ALDLL
Sbjct: 232 HYLDQLNHILGILGSPSQEDL-NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLL 290
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRL 364
D+ML F+P RI +AL+HPYL Y+DP DE PI + F+FD L + LK L
Sbjct: 291 DKMLTFNPHKRIEVEQALAHPYLEQYYDPSDE----PIAEAPFKFDMELDDLPKEKLKEL 346
Query: 365 LWNE 368
++ E
Sbjct: 347 IFEE 350
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 350 bits (898), Expect = 2e-96
Identities = 183/364 (50%), Positives = 239/364 (65%), Gaps = 32/364 (8%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKH 65
VF++ + S +GEGAYG+VCSA + VAIKKI PFE + RTLREIKIL
Sbjct: 18 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLR 77
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRAL 125
F+HENII I D+ + + EQ +VYI+Q+LM+TDL++++ TQ LS DH+ YF+YQ LR L
Sbjct: 78 FRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGL 137
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
K +H +NV+HRDLKPSNLLLN+ CDLKICDFGLAR+
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVA----------------------- 174
Query: 186 AANDGDPAISG-MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
D D +G +TEYVATRWYRAPE+ML + Y+KS+D+WS GCILAE+L +P+FPGK
Sbjct: 175 ---DPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGK 231
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
Y DQL I LG+P++++L + N +AR Y+ SLP K+ W R FPNA + ALDLL
Sbjct: 232 HYLDQLKHILGILGSPSQEDL-NCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLL 290
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRL 364
D+ML F+P RI +AL+HPYL Y+DP DE PI + F+FD L + LK L
Sbjct: 291 DKMLTFNPHKRIEVEQALAHPYLEQYYDPSDE----PIAEAPFKFDMELDDLPKEKLKEL 346
Query: 365 LWNE 368
++ E
Sbjct: 347 IFEE 350
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 336 bits (862), Expect = 3e-92
Identities = 176/363 (48%), Positives = 232/363 (63%), Gaps = 30/363 (8%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKH 65
+F ++ + S +GEGAYG+V SA + + VAIKKI PFE F RTLREIKIL
Sbjct: 89 LFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNR 148
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRAL 125
F+HENII+I ++ + + + ++YI+Q LM+TDL++++ TQ+LS DHV YF+YQ LR L
Sbjct: 149 FKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGL 208
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
K +H +NV+HRDLKPSNLLLN+ CDLKICDFGLAR+ +
Sbjct: 209 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGF-------------- 254
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
+TEYVATRWYRAPE+ML + Y+KS+DVWS GCILAE+L +PLFPGK
Sbjct: 255 -----------LTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKH 303
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
Y DQL LI +G+P+ +L + + N +AR Y+ SLP PK W R +P A ALDLLD
Sbjct: 304 YLDQLNLILAVVGSPSNADL-QCIINDKARSYLISLPHKPKQPWARLYPGADPRALDLLD 362
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLL 365
+ML F+P RI +AL+HPYL Y+DP DEP + +FD L + LK L+
Sbjct: 363 KMLTFNPHNRIDIEQALAHPYLEQYYDPGDEPVCEEPFTLEMEFDD----LPKEKLKELI 418
Query: 366 WNE 368
W E
Sbjct: 419 WEE 421
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 336 bits (862), Expect = 3e-92
Identities = 176/363 (48%), Positives = 232/363 (63%), Gaps = 30/363 (8%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKH 65
+F ++ + S +GEGAYG+V SA + + VAIKKI PFE F RTLREIKIL
Sbjct: 21 LFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISPFEHQTFCQRTLREIKILNR 80
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRAL 125
F+HENII+I ++ + + + ++YI+Q LM+TDL++++ TQ+LS DHV YF+YQ LR L
Sbjct: 81 FKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQKLSNDHVCYFLYQILRGL 140
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
K +H +NV+HRDLKPSNLLLN+ CDLKICDFGLAR+ +
Sbjct: 141 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVTDPQTDHTGF-------------- 186
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
+TEYVATRWYRAPE+ML + Y+KS+DVWS GCILAE+L +PLFPGK
Sbjct: 187 -----------LTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKH 235
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
Y DQL LI +G+P+ +L + + N +AR Y+ SLP PK W R +P A ALDLLD
Sbjct: 236 YLDQLNLILAVVGSPSNADL-QCIINDKARSYLISLPHKPKQPWARLYPGADPRALDLLD 294
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLL 365
+ML F+P RI +AL+HPYL Y+DP DEP + +FD L + LK L+
Sbjct: 295 KMLTFNPHNRIDIEQALAHPYLEQYYDPGDEPVCEEPFTLEMEFDD----LPKEKLKELI 350
Query: 366 WNE 368
W E
Sbjct: 351 WEE 353
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 335 bits (859), Expect = 6e-92
Identities = 173/362 (47%), Positives = 232/362 (63%), Gaps = 30/362 (8%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF 66
F++ + +GEGAYG+V SA VAIKKI PFE + RTLREI+IL F
Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 95
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALK 126
+HEN+I I D+ + S+ E +VYI+Q+LM+TDL++++ +Q+LS DH+ YF+YQ LR LK
Sbjct: 96 RHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLK 155
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
+H +NV+HRDLKPSNLL+N+ CDLKICDFGLARI
Sbjct: 156 YIHSANVLHRDLKPSNLLINTTCDLKICDFGLARI------------------------- 190
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
A+ +TEYVATRWYRAPE+ML + Y+KS+D+WS GCILAE+L +P+FPGK Y
Sbjct: 191 ADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHY 250
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
DQL I LG+P++++L + N +AR Y++SLP K+ W + FP + + ALDLLDR
Sbjct: 251 LDQLNHILGILGSPSQEDL-NCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDR 309
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
ML F+P RIT EAL+HPYL Y+DP DE P+ F F L + LK L++
Sbjct: 310 MLTFNPNKRITVEEALAHPYLEQYYDPTDE----PVAEEPFTFAMELDDLPKERLKELIF 365
Query: 367 NE 368
E
Sbjct: 366 QE 367
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 334 bits (856), Expect = 1e-91
Identities = 177/369 (47%), Positives = 244/369 (65%), Gaps = 38/369 (10%)
Query: 6 VFNISSEFQLQSL-LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKIL 63
+F ++++++ + +G+GAYG+VCSA + + E VAIKKI F+ + + RTLREIK+L
Sbjct: 55 IFEVTAKYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLL 114
Query: 64 KHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTL 122
+H HENI++I D+ P FN+VYI ELM TDLH++I + Q LSE+H QYF+YQ L
Sbjct: 115 RHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQIL 174
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
R LK +H +NV+HRDLKPSNLLLN+NCDLKICDFGLAR+ SE
Sbjct: 175 RGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESDF--------------- 219
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
MTEYV TRWYRAPE++L ++ Y+ ++DVWS GCI EL+ ++PLFP
Sbjct: 220 --------------MTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFP 265
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
G+D+ QL L+ + +GTP+E+EL L EN A+ YIR LP +P+ + +FP A+D
Sbjct: 266 GRDHVHQLRLLMELIGTPSEEELEFLNEN--AKRYIRQLPPYPRQSITDKFPTVHPLAID 323
Query: 303 LLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLK 362
L+++ML FDPR RIT +AL+HPYL S HD DEPE T IP F FD L+ + +K
Sbjct: 324 LIEKMLTFDPRRRITVLDALAHPYLNSLHDISDEPECT-IP---FNFDFENHALSEEQMK 379
Query: 363 RLLWNEIVS 371
L++ E ++
Sbjct: 380 ELIYREALA 388
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 327 bits (837), Expect = 2e-89
Identities = 170/354 (48%), Positives = 232/354 (65%), Gaps = 36/354 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GAYG+VC+A + +GE VAIKKI F+ + + RTLREIK+LKH HEN+I++ D+
Sbjct: 49 IGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDI 108
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
KP E FN+VYI+ ELM TDLH++I + Q L++DH ++F+YQ LR LK +H +NV+HR
Sbjct: 109 IKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHR 168
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKPSNLLLN+NCDLK+ DFGLAR SE
Sbjct: 169 DLKPSNLLLNANCDLKLGDFGLARTKSETDF----------------------------- 199
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MTEYV TRWYRAPE++L ++Y+ ++D+WS GCIL E + ++PLFPGKDY QL LI +
Sbjct: 200 MTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITEL 259
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
+G+P + L + + AR Y+R LP++P+ N+ RFPN SA A+DLL++ML FDP RI
Sbjct: 260 IGSPDDSSL-GFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRI 318
Query: 317 TATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWNEIV 370
T EAL HPYL HD ++E P+ F FD + L +++K L++ E V
Sbjct: 319 TVDEALCHPYLAPLHDINEE----PVCVRPFNFDFEQPTLTEENIKELIYRETV 368
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 323 bits (827), Expect = 3e-88
Identities = 174/369 (47%), Positives = 237/369 (64%), Gaps = 37/369 (10%)
Query: 6 VFNISSEFQLQSL-LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKIL 63
+F I+S+++ + +G GAYG+VCS + E+VA+KKI F+ + + RTLREIK+L
Sbjct: 30 LFEITSKYRPPIIPIGRGAYGIVCSVLDTETNELVAMKKIANAFDNHMDAKRTLREIKLL 89
Query: 64 KHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTL 122
+H HENII+I DV P QF++VYI ELM TDLH++I + Q LSE+H QYF+YQ L
Sbjct: 90 RHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQIIRSNQSLSEEHCQYFLYQLL 149
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
R LK +H +N+IHRDLKPSNLLLN+NCDLKICDFGLAR SE
Sbjct: 150 RGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLARPTSE------------------ 191
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
ND MTEYV TRWYRAPE++L ++ Y+ ++DVWS GCI EL+ ++PLFP
Sbjct: 192 -----ND------FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFP 240
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
GKD+ Q+ L+ + LGTPTE +L N A+ YIR LP P+ + F + + A+D
Sbjct: 241 GKDHVHQMRLLTELLGTPTESDL-GFTHNEDAKRYIRQLPNFPRQPLAKLFSHVNPMAID 299
Query: 303 LLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLK 362
L+DRML FDP RIT +AL+H YL HDP+DE PI F F+ + L+ + +K
Sbjct: 300 LVDRMLTFDPNRRITVEQALNHQYLAKLHDPNDE----PICQKPFSFEFEQQPLDEEQIK 355
Query: 363 RLLWNEIVS 371
+++ E ++
Sbjct: 356 EMIYQEAIA 364
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 320 bits (820), Expect = 2e-87
Identities = 172/377 (45%), Positives = 240/377 (63%), Gaps = 44/377 (11%)
Query: 2 GKRIVFNISSE-FQLQSL-------LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLF 52
G+ +++N+ F+L S +G GAYG+VC A + + E VAIKKI F+ +
Sbjct: 14 GRYVMYNVLGNIFELSSKYIPPIEPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVD 73
Query: 53 SIRTLREIKILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSE 111
+ RTLREIK+L H H+N+I I D+ + E+F +VYI+ ELM TDLH++I TQ L++
Sbjct: 74 AKRTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMDTDLHQIIRSTQTLTD 133
Query: 112 DHVQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXX 171
DH QYF+YQ LR LK +H +NV+HRDLKPSNL+LN+NCDLKICDFGLAR +E
Sbjct: 134 DHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETEI---- 189
Query: 172 XXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCIL 231
MTEYV TRWYRAPE++L +++Y+ ++D+WS GCI
Sbjct: 190 -------------------------MTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIF 224
Query: 232 AELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRR 291
E+L ++ LFPGKDY QL LI + LG+P + +L + + + AR+Y++ LP K ++R
Sbjct: 225 MEILRRETLFPGKDYVQQLKLITELLGSPDDSDL-DFLRSDNARKYVKQLPHVQKQSFRE 283
Query: 292 RFPNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQ 351
+FPN S ALDL ++ML FDP RIT EAL PYL S H+ ++EP P P F FD
Sbjct: 284 KFPNISPMALDLAEKMLVFDPSKRITVDEALKQPYLASLHEINEEPT-CPTP---FSFDF 339
Query: 352 WKSRLNTKDLKRLLWNE 368
++ L+ +D+K L+W E
Sbjct: 340 EETALDEQDIKELVWRE 356
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 312 bits (799), Expect = 6e-85
Identities = 165/355 (46%), Positives = 230/355 (64%), Gaps = 37/355 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GA G+VCSA + E VAIKKI + F+ + + RTLREIK+L+HF HENI++I DV
Sbjct: 66 IGRGACGIVCSAVDSETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVAIRDV 125
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
P + F +VYI+ ELM+ DL+R + + QEL++DH YF+YQ LR LK +H +NV+HR
Sbjct: 126 ILPPQRDSFEDVYIVNELMEFDLYRTLKSDQELTKDHGMYFMYQILRGLKYIHSANVLHR 185
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKPSNLLL++ CDLKICDFGLAR P +
Sbjct: 186 DLKPSNLLLSTQCDLKICDFGLAR-----------------------------ATPESNL 216
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MTEYV TRWYRAPE++L ++ Y+ ++DVWS GCI E++ ++PLFPGKD +QL L+ +
Sbjct: 217 MTEYVVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLEL 276
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
+GTP+E+EL L E A+ YIR LP P+ ++ +FPN A+DL+++ML FDP+ RI
Sbjct: 277 IGTPSEEELGSLSE--YAKRYIRQLPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRI 334
Query: 317 TATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWNEIVS 371
+ EAL+HPYL S+HD DEPE S F FD + + + + L++ E ++
Sbjct: 335 SVKEALAHPYLSSFHDITDEPE----CSEPFNFDLDEHPFSEEQFRELIYCEALA 385
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 309 bits (792), Expect = 4e-84
Identities = 161/368 (43%), Positives = 231/368 (62%), Gaps = 36/368 (9%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEP-FEKPLFSIRTLREIKILK 64
+F I +++ +G GAYGVVCS+ ++ S E VAIKKI FE + ++RTLRE+K+L+
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLR 84
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLR 123
H +HEN++++ DV + F +VY++ ELM TDLH++I + Q LS DH QYF++Q LR
Sbjct: 85 HLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLR 144
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
LK +H +N++HRDLKP NLL+N+NCDLKICDFGLAR + +
Sbjct: 145 GLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSNTKGQF--------------- 189
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
MTEYV TRWYRAPE++L Y S+DVWS GCI AELLG++P+FPG
Sbjct: 190 -------------MTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPG 236
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
+ +Q+ LI LG+ E++L E ++N +A+ YI SLP P I++ R +P A+ A+DL
Sbjct: 237 TECLNQIKLIINILGSQREEDL-EFIDNPKAKRYIESLPYSPGISFSRLYPGANVLAIDL 295
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPD-DEPEGTPIPSSFFQFDQWKSRLNTKDLK 362
L +ML DP RI+ TEAL HPY+ +DP + P PI + + L + ++
Sbjct: 296 LQKMLVLDPSKRISVTEALQHPYMAPLYDPSANPPAQVPIDLDVDEDED----LGAEMIR 351
Query: 363 RLLWNEIV 370
L+W E++
Sbjct: 352 ELMWKEMI 359
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 307 bits (786), Expect = 2e-83
Identities = 160/340 (47%), Positives = 224/340 (65%), Gaps = 28/340 (8%)
Query: 5 IVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKIL 63
+ F++ E+++ +G GAYGVV SA+ + +G+ VAIKKI F+ + RTLRE+KIL
Sbjct: 47 VTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKIL 106
Query: 64 KHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQT 121
KHF+H+NII+I D+ +P+ + +F VY++ +LM++DLH++I +Q L+ +HV+YF+YQ
Sbjct: 107 KHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQL 166
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H + VIHRDLKPSNLL+N NC+LKI DFG+AR
Sbjct: 167 LRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMAR-----------------GLCT 209
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
SP+ MTEYVATRWYRAPE+ML+ +Y++++D+WS GCI E+L ++ LF
Sbjct: 210 SPAEHQ-------YFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLF 262
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PGK+Y QL LI LGTP+ +++ V R R YI+SLP + W +P A AL
Sbjct: 263 PGKNYVHQLQLIMMVLGTPS-PAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQAL 321
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTP 341
LL RML+F+P RI+A AL HP+L YHDPDDEP+ P
Sbjct: 322 SLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAP 361
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 307 bits (786), Expect = 2e-83
Identities = 160/340 (47%), Positives = 224/340 (65%), Gaps = 28/340 (8%)
Query: 5 IVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKIL 63
+ F++ E+++ +G GAYGVV SA+ + +G+ VAIKKI F+ + RTLRE+KIL
Sbjct: 47 VTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKIL 106
Query: 64 KHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQT 121
KHF+H+NII+I D+ +P+ + +F VY++ +LM++DLH++I +Q L+ +HV+YF+YQ
Sbjct: 107 KHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQL 166
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H + VIHRDLKPSNLL+N NC+LKI DFG+AR
Sbjct: 167 LRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMAR-----------------GLCT 209
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
SP+ MTEYVATRWYRAPE+ML+ +Y++++D+WS GCI E+L ++ LF
Sbjct: 210 SPAEHQ-------YFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLF 262
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PGK+Y QL LI LGTP+ +++ V R R YI+SLP + W +P A AL
Sbjct: 263 PGKNYVHQLQLIMMVLGTPS-PAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQAL 321
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTP 341
LL RML+F+P RI+A AL HP+L YHDPDDEP+ P
Sbjct: 322 SLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAP 361
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 305 bits (782), Expect = 5e-83
Identities = 161/368 (43%), Positives = 229/368 (61%), Gaps = 38/368 (10%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEP-FEKPLFSIRTLREIKILK 64
+F I +++ +G GAYGVVCS+ + + E VAIKKI +E + ++RTLRE+K+L+
Sbjct: 25 LFEIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLR 84
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLR 123
H +HEN+I++ DV P F +VY++ ELM TDLH++I + Q LS DH QYF++Q LR
Sbjct: 85 HLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLR 144
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
LK +H +N++HRDLKP NLL+N+NCDLKICDFGLAR + +
Sbjct: 145 GLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASNTKGQF--------------- 189
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
MTEYV TRWYRAPE++L Y S+DVWS GCI AELLG++P+F G
Sbjct: 190 -------------MTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQG 236
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
+ +QL LI LG+ E++L E ++N +A+ YIRSLP P ++ R +P A A+DL
Sbjct: 237 TECLNQLKLIVNILGSQREEDL-EFIDNPKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDL 295
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPD-DEPEGTPIPSSFFQFDQWKSRLNTKDLK 362
L +ML FDP RI+ +EAL HPY+ +DP+ + P PI L + ++
Sbjct: 296 LQKMLVFDPSKRISVSEALQHPYMAPLYDPNANPPAQVPIDLDV------DEDLREEMIR 349
Query: 363 RLLWNEIV 370
++WNE++
Sbjct: 350 EMMWNEML 357
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 303 bits (776), Expect = 3e-82
Identities = 160/336 (47%), Positives = 220/336 (64%), Gaps = 36/336 (10%)
Query: 37 EIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDVQKPSSFEQFNEVYIIQEL 95
E +AIKKI + F+ + + RTLREIK+L+H +HEN++ I D+ +P E F +VYI+ EL
Sbjct: 64 EEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFEL 123
Query: 96 MQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKIC 154
M TDLH++I + Q L++DH QYF+YQ LR LK +H +NV+HRDLKPSNLLLNSNCDLKI
Sbjct: 124 MDTDLHQIIRSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKIT 183
Query: 155 DFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLT 214
DFGLAR SE MTEYV TRWYRAPE++L
Sbjct: 184 DFGLARTTSETEY-----------------------------MTEYVVTRWYRAPELLLN 214
Query: 215 AAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRA 274
+++Y+ ++DVWS GCI AE++ ++PLFPGKDY QL LI + +G+P L E + + A
Sbjct: 215 SSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSPDGASL-EFLRSANA 273
Query: 275 REYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPD 334
R+Y++ LPK P+ N+ RFP+ ++ A+DLL++ML FDP RIT EAL +PYL + HD +
Sbjct: 274 RKYVKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRITVEEALCYPYLSALHDLN 333
Query: 335 DEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWNEIV 370
DE P+ S+ F F +++K L+W E V
Sbjct: 334 DE----PVCSNHFSFHFEDPSSTEEEIKELVWLESV 365
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 302 bits (774), Expect = 5e-82
Identities = 176/375 (46%), Positives = 237/375 (62%), Gaps = 40/375 (10%)
Query: 6 VFN----ISSEFQLQSLLGEGAYGVVCSAKHKPSG--EIVAIKKI-EPFEKPLFSIRTLR 58
VFN + F++ LG+GAYG+VC+A++ S E VAIKKI F K + + R LR
Sbjct: 10 VFNQEMYVEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALR 69
Query: 59 EIKILKHFQ-HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQY 116
EIK+L HF+ H NI I+D+ + + FNEVYI +ELM+ DL+ +I + Q L++ H Q
Sbjct: 70 EIKLLIHFRNHRNITCIYDLDIINPYN-FNEVYIYEELMEADLNAIIKSGQPLTDAHFQS 128
Query: 117 FVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXX 176
F+YQ L LK +H +NVIHRDLKP NLL+N++C+LKICDFGLAR SE
Sbjct: 129 FIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENP---------- 178
Query: 177 XXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLG 236
+ +P MTEYVATRWYRAPE+ML+ + Y K +DVWS GCILAELLG
Sbjct: 179 ------------EENPGF--MTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLG 224
Query: 237 KQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA 296
PLF GKD+ QL LI LGTP E+ L + + RA+EY+RSLPK I + FP A
Sbjct: 225 GTPLFKGKDFVHQLNLILHQLGTPDEETLSH-ISSSRAQEYVRSLPKQRPIPFETNFPKA 283
Query: 297 SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRL 356
+ ALDLL ++L FDP RI+ +AL HPYL +HDP DE P+ S F F ++
Sbjct: 284 NPLALDLLAKLLAFDPNRRISVDDALEHPYLAVWHDPSDE----PVCDSVFDF-SFEYIE 338
Query: 357 NTKDLKRLLWNEIVS 371
+ +L+R++ +E+++
Sbjct: 339 DANELRRVILDEVLN 353
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 302 bits (774), Expect = 5e-82
Identities = 160/374 (42%), Positives = 230/374 (60%), Gaps = 47/374 (12%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKI 62
+ ++ + +Q S +G GAYG VC+A +G VA+KK+ PF+ + + RT RE+++
Sbjct: 15 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 63 LKHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQT 121
LKH +HEN+I + DV P+ S E+FN+VY++ LM DL+ ++ Q+L++DHVQ+ +YQ
Sbjct: 75 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQI 134
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H +++IHRDLKPSNL +N +C+LKI DFGLAR +
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE---------------- 178
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
MT YVATRWYRAPE+ML Y++++D+WS GCI+AELL + LF
Sbjct: 179 ---------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 223
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PG D+ DQL LI + +GTP EL++ + + AR YI+SL + PK+N+ F A+ A+
Sbjct: 224 PGTDHIDQLKLILRLVGTP-GAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAV 282
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSF----FQFDQWKSRLN 357
DLL++ML D RITA +AL+H Y YHDPDDEP P SF D+WKS
Sbjct: 283 DLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKS--- 339
Query: 358 TKDLKRLLWNEIVS 371
L ++E++S
Sbjct: 340 ------LTYDEVIS 347
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 301 bits (772), Expect = 8e-82
Identities = 157/366 (42%), Positives = 231/366 (62%), Gaps = 41/366 (11%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKH 65
F I++ + +G GA+G+VCSAK + +G VA+KKI +PF P+ + RT RE+K+LKH
Sbjct: 14 FEITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKH 73
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRAL 125
+HENIIS+ D+ F ++Y + EL+ TDLHR++ ++ L +QYF+YQ LR L
Sbjct: 74 LRHENIISLSDI----FISPFEDIYFVTELLGTDLHRLLTSRPLETQFIQYFLYQILRGL 129
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
K +H + VIHRDLKPSN+L+N NCDLKICDFGLARI
Sbjct: 130 KFVHSAGVIHRDLKPSNILINENCDLKICDFGLARI------------------------ 165
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
DP MT YV+TR+YRAPE+MLT +Y+ +D+WS GCI AE++ +PLFPG+D
Sbjct: 166 ----QDPQ---MTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRD 218
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
+ +Q +I + LGTP E++E + ++ +++SLP+ K+ + +F NA A+DLL+
Sbjct: 219 HVNQFSIITELLGTP-PMEVIETICSKNTLRFVQSLPQKEKVPFAEKFKNADPDAIDLLE 277
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLL 365
+ML FDPR RI+A +AL+H YL YHDP DE P+ F + + L + K ++
Sbjct: 278 KMLVFDPRKRISAADALAHNYLAPYHDPTDE----PVADEVFDWSFQDNDLPVETWKVMM 333
Query: 366 WNEIVS 371
++E++S
Sbjct: 334 YSEVLS 339
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 301 bits (771), Expect = 1e-81
Identities = 159/367 (43%), Positives = 231/367 (62%), Gaps = 36/367 (9%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEP-FEKPLFSIRTLREIKILK 64
+F I +++ +G GAYGVVCS+ ++ + E VAIKKI FE + ++RTLRE+K+L+
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLR 84
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLR 123
H +HEN+I++ DV P++ F +VY++ ELM TDLH++I + Q LS+DH +YF++Q LR
Sbjct: 85 HVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLR 144
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
LK LH +N++HRDLKP NLL+N+NCDLKICDFGLAR
Sbjct: 145 GLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLAR----------------------- 181
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+S N+ MTEYV TRWYRAPE++L Y S+DVWS GCI AE+LG++P+FPG
Sbjct: 182 TSQGNE-----QFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPG 236
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
+ +QL LI +G+ E + + ++N +AR +I+SLP + +P A+ A+DL
Sbjct: 237 TECLNQLKLIINVVGSQQESD-IRFIDNPKARRFIKSLPYSRGTHLSNLYPQANPLAIDL 295
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L RML FDP RI+ T+AL HPY+ DP P +P S D+ + ++
Sbjct: 296 LQRMLVFDPTKRISVTDALLHPYMAGLFDPGSNPP-AHVPIS-LDIDE---NMEEPVIRE 350
Query: 364 LLWNEIV 370
++WNE++
Sbjct: 351 MMWNEML 357
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 295 bits (755), Expect = 7e-80
Identities = 157/374 (41%), Positives = 226/374 (59%), Gaps = 47/374 (12%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKI 62
+ ++ + +Q S +G GAYG VC+A +G VA+KK+ PF+ + + RT RE+++
Sbjct: 15 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 63 LKHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQT 121
LKH +HEN+I + DV P+ S E+FN+VY++ LM DL+ ++ Q+L++DHVQ+ +YQ
Sbjct: 75 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQI 134
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H +++IHRDLKPSNL +N +C+LKI DFGLAR +
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE---------------- 178
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
MT YVATRWYRAPE+ML Y++++D+WS GCI+AELL + LF
Sbjct: 179 ---------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 223
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PG D+ +QL I + GTP L+ + + AR YI+SL + PK+N+ F A+ A+
Sbjct: 224 PGTDHINQLQQIMRLTGTPPAY-LINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAV 282
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSF----FQFDQWKSRLN 357
DLL++ML D RITA +AL+H Y YHDPDDEP P SF D+WKS
Sbjct: 283 DLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKS--- 339
Query: 358 TKDLKRLLWNEIVS 371
L ++E++S
Sbjct: 340 ------LTYDEVIS 347
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 295 bits (754), Expect = 1e-79
Identities = 158/348 (45%), Positives = 212/348 (60%), Gaps = 37/348 (10%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKI 62
R + I +Q +G+GAYG VC A + + VAIKK+ PF+ + + RT RE+++
Sbjct: 15 RTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRL 74
Query: 63 LKHFQHENIISIFDVQKPS----SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFV 118
LKH HEN+I + DV P S +QF +VY++ LM DL+ +I TQ+LS+DHVQ+ V
Sbjct: 75 LKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLV 134
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXX 178
YQ LR LK +H + VIHRDLKPSN+ +N +C+L+I DFGLAR
Sbjct: 135 YQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR------------------ 176
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
PA S MT YVATRWYRAPE+ML Y+++ D+WS GCI+AELL +
Sbjct: 177 -------------PAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGR 223
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA 298
LFPG D+ QL LI + LGTP + E + + + AR YIRSLP P+ N+R F A+
Sbjct: 224 TLFPGTDHIHQLNLIMEVLGTPAD-EFMSRISSESARNYIRSLPVMPRRNFRDIFRGANP 282
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSF 346
A+DLL++ML+ D RITA +AL+HPY+ YHDP DE SF
Sbjct: 283 LAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSF 330
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 294 bits (752), Expect = 2e-79
Identities = 153/367 (41%), Positives = 231/367 (62%), Gaps = 38/367 (10%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEP-FEKPLFSIRTLREIKILK 64
+F I +++ +G GAYGVVCS+ + + E VAIKKI FE + ++RTLRE+K+L+
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVCSSINSETNERVAIKKIHNVFENRIDALRTLRELKLLR 84
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLR 123
H +HEN+IS+ DV P+ F +VY++ ELM +DL+++I + Q LS+DH +YF++Q LR
Sbjct: 85 HVRHENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKSSQSLSDDHCKYFLFQLLR 144
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
LK LH +N++HRDLKP NLL+N+NCDLKICDFGLAR +
Sbjct: 145 GLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYEQ------------------- 185
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
MTEYV TRWYRAPE++L Y S+DVWS GCI AE+LG++P+FPG
Sbjct: 186 ------------FMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPG 233
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
+ +QL LI +G+ + +L + ++N++AR +I+SLP ++ +P+A+ A+DL
Sbjct: 234 TECLNQLKLIINVVGSQQDWDL-QFIDNQKARRFIKSLPFSKGTHFSHIYPHANPLAIDL 292
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L RML FDP RI+ ++AL HPY+ +P+ P +P S + D+ + ++
Sbjct: 293 LQRMLVFDPTKRISVSDALLHPYMEGLLEPECNPSEN-VPVSSLEIDE---NMEGDMIRE 348
Query: 364 LLWNEIV 370
++W E++
Sbjct: 349 MMWEEML 355
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 290 bits (742), Expect = 2e-78
Identities = 157/354 (44%), Positives = 217/354 (60%), Gaps = 36/354 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GA G+VC+A + +GE VAIKKI F+ + + RTLREIK+L+H HEN+I+I D+
Sbjct: 81 IGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLRHMDHENVITIKDI 140
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+P + FN+VYI+ ELM TDL R++ + Q L+ D ++ VYQ LR LK +H +N++HR
Sbjct: 141 VRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQCRFLVYQLLRGLKYVHSANILHR 200
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DL+PSN+LLNS +LKI DFGLAR S+
Sbjct: 201 DLRPSNVLLNSKNELKIGDFGLARTTSDTDF----------------------------- 231
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MTEYV TRWYRAPE++L ++Y+ ++D+WS GCIL E++ QPLFPGKDY QL LI +
Sbjct: 232 MTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITEL 291
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
+G+P L + + AR Y+R LP++PK + RFP A+DLL+RML FDP RI
Sbjct: 292 VGSPDNSSL-GFLRSDNARRYVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRI 350
Query: 317 TATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWNEIV 370
+ EAL H YL +HD E P+ S+ F FD + +K L++ E V
Sbjct: 351 SVDEALGHAYLSPHHDVAKE----PVCSTPFSFDFEHPSCTEEHIKELIYKESV 400
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 289 bits (740), Expect = 4e-78
Identities = 164/371 (44%), Positives = 232/371 (62%), Gaps = 40/371 (10%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGE--IVAIKKI-EPFEKPLFSIRTLREIKIL 63
F++ FQL +G GAYG+VCSA+ + E VAIKK+ F K L R+LRE+K+L
Sbjct: 17 FSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLL 76
Query: 64 KHFQ-HENIISIFDVQ---KPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFV 118
+HF+ H+NI ++D+ P N +Y+ +ELM+ D+H++I + Q L++ H Q F
Sbjct: 77 RHFRGHKNITCLYDMDIVFYPDG--SINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFT 134
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXX 178
YQ L LK +H ++V+HRDLKP NLL+N++C LKICDFGLAR SE
Sbjct: 135 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQF------ 188
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
+TEYVATRWYRAPE+ML+ Y+K++DVWS GCILAE LG +
Sbjct: 189 ------------------LTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGK 230
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA 298
P+F GKDY +QL I Q LGTP + E + + ++ ++YI L PK+ + +PNA++
Sbjct: 231 PIFKGKDYVNQLNQILQVLGTPPD-ETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANS 289
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNT 358
ALDLL++ML FDP+ RIT EAL HPYL +HDP DE P+ S F+F ++S +
Sbjct: 290 QALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADE----PVCSEKFEF-SFESVNDM 344
Query: 359 KDLKRLLWNEI 369
+DLK+++ E+
Sbjct: 345 EDLKQMVIQEV 355
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 285 bits (729), Expect = 8e-77
Identities = 156/370 (42%), Positives = 220/370 (59%), Gaps = 39/370 (10%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKI 62
+ V+ + Q +G GAYG VCSA + VA+KK+ PF+ + + RT RE+++
Sbjct: 15 KTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRL 74
Query: 63 LKHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQT 121
LKH +HEN+I + DV P+ S E F+EVY++ LM DL+ ++ Q LS++HVQ+ VYQ
Sbjct: 75 LKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQL 134
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H + +IHRDLKPSN+ +N +C+L+I DFGLAR E
Sbjct: 135 LRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEE---------------- 178
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
MT YVATRWYRAPE+ML Y++++D+WS GCI+AELL + LF
Sbjct: 179 ---------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALF 223
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PG DY DQL I + +GTP+ + L + + + AR YI+SLP P+ + F A+ A+
Sbjct: 224 PGSDYIDQLKRIMEVVGTPSPEVLAK-ISSEHARTYIQSLPPMPQKDLSSIFRGANPLAI 282
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDL 361
DLL RML D R++A EAL+H Y YHDP+DEPE P S + K R ++
Sbjct: 283 DLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESV----EAKER-TLEEW 337
Query: 362 KRLLWNEIVS 371
K L + E++S
Sbjct: 338 KELTYQEVLS 347
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 280 bits (717), Expect = 2e-75
Identities = 156/364 (42%), Positives = 228/364 (61%), Gaps = 31/364 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEP-FEKPLFSIRTLREIKILKHFQH 68
++ F++Q ++G+G+YGVVCSA +GE VAIKKI FE + R LREIK+L+ +H
Sbjct: 10 ANRFKVQEVIGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRH 69
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+I+ I + P S +F ++Y++ ELM++DLH+VI +L+ +H Q+F+YQ LRALK
Sbjct: 70 PDIVEIKHIMLPPSRREFKDIYVVFELMESDLHQVIKANDDLTREHYQFFLYQLLRALKY 129
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H +NV HRDLKP N+L N+NC LKICDFGLAR+ A
Sbjct: 130 IHTANVYHRDLKPKNILANANCKLKICDFGLARV------------------------AF 165
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
ND P T+YVATRWYRAPE+ + ++Y+ ++D+WS GCI AE+L +PLFPGK+
Sbjct: 166 ND-TPTTIFWTDYVATRWYRAPELCGSFYSKYTPAIDIWSIGCIFAEVLMGKPLFPGKNV 224
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL L+ LGTP+ + + V N +AR Y+ S+ K P I + ++FPNA +L LL+R
Sbjct: 225 VHQLDLMTDLLGTPS-LDTISRVRNEKARRYLTSMRKKPPIPFAQKFPNADPLSLKLLER 283
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
+L FDP+ R TA EAL+ PY + EP PI F+F+ + ++ +D++ L+
Sbjct: 284 LLAFDPKDRPTAEEALADPYFKGLAKVEREPSCQPITKMEFEFE--RRKVTKEDIRELIS 341
Query: 367 NEIV 370
EI+
Sbjct: 342 REIL 345
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 279 bits (714), Expect = 4e-75
Identities = 147/333 (44%), Positives = 205/333 (61%), Gaps = 37/333 (11%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILK 64
VF I++ + + +G GA+G+VCSA + + VAIKKI +PF + + RT RE+K+LK
Sbjct: 16 VFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLK 75
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H +HEN+I + D+ ++Y + EL TDLHR++ T+ L + VQYF+YQ LR
Sbjct: 76 HLRHENLICLQDI----FLSPLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRG 131
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
LK +H + VIHRDLKPSN+L+N NCDLKICDFGLARI
Sbjct: 132 LKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI----------------------- 168
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
DP MT YV+TR+YRAPE+MLT +Y +D+WS GCI AE++ +PLFPGK
Sbjct: 169 -----QDPQ---MTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGK 220
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
D+ Q +I LG+P ++++ + + +++ SLP I + RF A+DLL
Sbjct: 221 DHVHQFSIITDLLGSP-PKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLL 279
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
++ML FDP+ RITA +AL+HPY YHDP DEP
Sbjct: 280 EKMLVFDPKKRITAADALAHPYSAPYHDPTDEP 312
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 278 bits (712), Expect = 7e-75
Identities = 153/364 (42%), Positives = 227/364 (62%), Gaps = 31/364 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
+S +Q+Q ++G+G+YGVV SA SGE VAIKKI + FE + R LREIK+L+ +H
Sbjct: 123 ASRYQIQEVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSDATRILREIKLLRLLRH 182
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+I+ I V P S +F ++Y++ ELM++DLH+VI +L+ +H Q+F+YQ LR LK
Sbjct: 183 PDIVEIKHVMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKF 242
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H +NV HRDLKP N+L NS+C LKICDFGLAR+ +
Sbjct: 243 IHTANVFHRDLKPKNILANSDCKLKICDFGLARV------------------------SF 278
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
ND AI T+YVATRWYRAPE+ + ++Y+ ++D+WS GCI AE+L +PLFPGK+
Sbjct: 279 NDAPSAIF-WTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNV 337
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL ++ LGTP E + + N +AR Y+ ++ + P + + +FP+ AL LL R
Sbjct: 338 VHQLDIMTDLLGTP-PPEAIARIRNEKARRYLGNMRRKPPVPFTHKFPHVDPLALRLLHR 396
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
+L FDP+ R +A EAL+ PY + D EP PIP F+F+ + ++ +D++ L++
Sbjct: 397 LLAFDPKDRPSAEEALADPYFYGLANVDREPSTQPIPKLEFEFE--RRKITKEDVRELIY 454
Query: 367 NEIV 370
EI+
Sbjct: 455 REIL 458
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 278 bits (710), Expect = 1e-74
Identities = 155/373 (41%), Positives = 214/373 (56%), Gaps = 42/373 (11%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKI 62
R + I +Q +G GAYG V A + + VAIKK+ PF+ + + RT RE+++
Sbjct: 16 RTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRL 75
Query: 63 LKHFQHENIISIFDVQKP----SSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFV 118
LKH HEN+I + D+ P S E F +VY++ LM DL+ +I Q LS+DHVQ+ V
Sbjct: 76 LKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLV 135
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXX 178
YQ LR LK +H + VIHRDLKPSN+ +N +C+L+I DFGLAR
Sbjct: 136 YQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR------------------ 177
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
P + MT YVATRWYRAPE+ML Y +++D+WS GCI+AEL+ ++
Sbjct: 178 -------------PTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRR 224
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA 298
LFPG D+ QL LI + LGTP E ++ + + AR YI+SLP +++ F NA+
Sbjct: 225 TLFPGTDHIHQLNLIMEMLGTP-PAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANP 283
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNT 358
A+DLL++ML+ D RITA EALSHPYL Y +P E P SF D L
Sbjct: 284 LAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFEDMD-----LPV 338
Query: 359 KDLKRLLWNEIVS 371
K L++ E+ +
Sbjct: 339 DKWKELIYKEVTN 351
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 277 bits (709), Expect = 2e-74
Identities = 152/364 (41%), Positives = 226/364 (61%), Gaps = 31/364 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
++ +++ ++G+G+YGVVC+A +GE VAIKKI + FE ++R LRE+K+L+ +H
Sbjct: 10 ANRYRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRH 69
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+I+ I + P S +F ++Y++ ELM++DLH+VI +L+ +H Q+F+YQ LRALK
Sbjct: 70 PDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRALKY 129
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H +NV HRDLKP N+L N+NC LK+CDFGLAR+ +
Sbjct: 130 MHTANVYHRDLKPKNILANANCKLKVCDFGLARV------------------------SF 165
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
ND P T+YVATRWYRAPE+ + ++Y+ ++D+WS GCI AE+L +PLFPGK
Sbjct: 166 ND-TPTTVFWTDYVATRWYRAPELCGSFCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSV 224
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL LI LGTP + E + V N +AR+Y+ + K + + ++FPNA AL LL R
Sbjct: 225 VHQLDLITDLLGTP-KSETIAGVRNEKARKYLNEMRKKNLVPFSQKFPNADPLALRLLQR 283
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
+L FDP+ R TA EAL+ PY + EP PI F+F+ + RL D++ L++
Sbjct: 284 LLAFDPKDRPTAAEALADPYFKCLAKVEREPSCQPISKMEFEFE--RRRLTKDDIRELIY 341
Query: 367 NEIV 370
EI+
Sbjct: 342 REIL 345
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 275 bits (703), Expect = 8e-74
Identities = 150/345 (43%), Positives = 208/345 (59%), Gaps = 40/345 (11%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GAYG VCSA K SGE VAIKK+ PF+ +F+ R RE+ +LKH QHEN+I + DV
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 78 QKP-SSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
P SS F + Y++ MQTDL + I+ E SE+ +QY VYQ L+ LK +H + V+HR
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQK-IMGMEFSEEKIQYLVYQMLKGLKYIHSAGVVHR 149
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NL +N +C+LKI DFGLAR A +
Sbjct: 150 DLKPGNLAVNEDCELKILDFGLAR-------------------------------HADAE 178
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT YV TRWYRAPEV+L+ Y++++D+WS GCI+AE+L + LF GKDY DQL I +
Sbjct: 179 MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKV 238
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
G P E V+ + ++ A+ YI+SLP+ P+ ++ + FP AS A DLL++ML+ D R+
Sbjct: 239 TGVP-GTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRL 297
Query: 317 TATEALSHPYLVSYHDPDDEPEG-TPIPSSF----FQFDQWKSRL 356
TA +AL+HP+ + DP++E E P S D+WK +
Sbjct: 298 TAAQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHI 342
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 273 bits (697), Expect = 4e-73
Identities = 149/357 (41%), Positives = 209/357 (57%), Gaps = 47/357 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GAYG VC+A+ SG VAIKK PF+ + + RT RE+++L+ HENII + DV
Sbjct: 41 IGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDV 100
Query: 78 QKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
P+ + +VY + LM DL ++ Q L++DH+Q+ VYQ LR LK +H +++IHR
Sbjct: 101 FTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHR 160
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKPSN+ +N +C+LKI DFGLAR S
Sbjct: 161 DLKPSNIAVNEDCELKILDFGLARQTD-------------------------------SE 189
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT YVATRWYRAPE+ML Y++++DVWS GCILAEL+ + LFPG D+ DQL I
Sbjct: 190 MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSV 249
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
GTP ++E ++ + + AR YIR+LPK + +++R F A+ A+DLL++ML DP R
Sbjct: 250 TGTP-DEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRP 308
Query: 317 TATEALSHPYLVSYHDPDDEPEGTPIPSS----FFQFDQWKSRLNTKDLKRLLWNEI 369
TA EA+ H YL +YHD DEP + + D+W K+++W EI
Sbjct: 309 TAKEAMEHEYLAAYHDETDEPIAEEMDLNDDVRADTIDEW---------KKIIWEEI 356
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 270 bits (691), Expect = 2e-72
Identities = 150/364 (41%), Positives = 225/364 (61%), Gaps = 31/364 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
++ +Q+Q ++G+G+YGVV SA +GE VAIKKI + FE + R LREIK+L+ +H
Sbjct: 101 ANRYQIQEVVGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIKLLRLLRH 160
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+++ I + P S +F ++Y++ ELM++DLH+VI +L+ +H Q+F+YQ LR LK
Sbjct: 161 PDVVEIKHIMLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKY 220
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H +NV HRDLKP N+L N++C LKICDFGLAR+ +
Sbjct: 221 VHAANVFHRDLKPKNILANADCKLKICDFGLARV------------------------SF 256
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
ND AI T+YVATRWYRAPE+ + ++Y+ ++D+WS GCI AE+L +PLFPGK+
Sbjct: 257 NDAPTAIF-WTDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNV 315
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL L+ LGTP E + + N +AR Y+ S+ K + + +FP A AL LL+R
Sbjct: 316 VHQLDLMTDFLGTP-PPESISRIRNEKARRYLSSMRKKQPVPFSHKFPKADPLALRLLER 374
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
+L FDP+ R +A +AL+ PY + + EP PI S +FD + +L D++ L++
Sbjct: 375 LLAFDPKDRASAEDALADPYFSGLSNSEREPTTQPI--SKLEFDFERKKLVKDDVRELIY 432
Query: 367 NEIV 370
EI+
Sbjct: 433 REIL 436
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 270 bits (690), Expect = 3e-72
Identities = 151/361 (41%), Positives = 222/361 (60%), Gaps = 31/361 (8%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEP-FEKPLFSIRTLREIKILKHFQHE 69
S ++++ ++G+G+YGVVCSA +GE VAIKKI FE + R LREIK+L+ +H
Sbjct: 23 SRYRIEEVIGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHP 82
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKVL 128
+I+ I + P S +F ++Y++ ELM++DLH+VI +L+ +H Q+F+YQ LR LK +
Sbjct: 83 DIVEIKHILLPPSRREFRDIYVVFELMESDLHQVIKANDDLTPEHYQFFLYQLLRGLKYI 142
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H +NV HRDLKP N+L N++C LKICDFGLAR+ A N
Sbjct: 143 HTANVFHRDLKPKNILANADCKLKICDFGLARV------------------------AFN 178
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDYR 247
D AI T+YVATRWYRAPE+ + ++Y+ ++D+WS GCI AELL +PLFPGK+
Sbjct: 179 DTPTAIF-WTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAELLTGKPLFPGKNVV 237
Query: 248 DQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRM 307
QL L+ LGTP+ E + V N +AR Y+ S+ K I + +FP+ AL LL++M
Sbjct: 238 HQLDLMTDMLGTPS-AEAIGRVRNEKARRYLSSMRKKKPIPFSHKFPHTDPLALRLLEKM 296
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWN 367
L F+P+ R TA EAL+ Y + EP P+ F+F+ + R+ +D++ L++
Sbjct: 297 LSFEPKDRPTAEEALADVYFKGLAKVEREPSAQPVTKLEFEFE--RRRITKEDVRELIYR 354
Query: 368 E 368
E
Sbjct: 355 E 355
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 269 bits (687), Expect = 6e-72
Identities = 150/364 (41%), Positives = 222/364 (60%), Gaps = 31/364 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
++ +++ ++G+G+YGVVC+A +GE VAIKKI + FE ++R LRE+K+L+ +H
Sbjct: 10 ANRYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRH 69
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+I+ I + P S +F ++Y++ ELM++DLH+VI +L+ +H Q+F+YQ LRALK
Sbjct: 70 PDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRALKF 129
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H +NV HRDLKP N+L N+NC LK+CDFGLAR+ A
Sbjct: 130 MHTANVYHRDLKPKNILANANCKLKVCDFGLARV------------------------AF 165
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
ND P T+YVATRWYRAPE+ + ++Y+ ++DVWS GCI AE+L +PLFPGK
Sbjct: 166 ND-TPTTVFWTDYVATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSV 224
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL LI LGTP + E + V N +AR+Y+ + K + + ++F A AL LL R
Sbjct: 225 VHQLELITDLLGTP-KSETISGVRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQR 283
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
+L FDP+ R T EAL+ PY + EP I F+F+ + RL D++ L++
Sbjct: 284 LLAFDPKDRPTPAEALADPYFKGLSKIEREPSSQQISKMEFEFE--RRRLTKDDIRELIY 341
Query: 367 NEIV 370
EI+
Sbjct: 342 REIL 345
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 263 bits (673), Expect = 2e-70
Identities = 147/364 (40%), Positives = 224/364 (61%), Gaps = 31/364 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
++ +Q+Q ++G+G+YGVV SA +GE VAIKKI + F+ + R LREIK+L+ H
Sbjct: 87 ANRYQIQEVVGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLH 146
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+++ I + P S +F +VY++ ELM++DLH+VI +L+ +H Q+F+YQ LR LK
Sbjct: 147 PDVVEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPEHHQFFLYQLLRGLKY 206
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H +NV HRDLKP N+L N++C LKICDFGLAR+ +
Sbjct: 207 VHAANVFHRDLKPKNILANADCKLKICDFGLARV------------------------SF 242
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
ND AI T+YVATRWYRAPE+ + ++Y+ ++D+WS GCI AE+L +PLFPGK+
Sbjct: 243 NDAPTAIF-WTDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAEMLLGKPLFPGKNV 301
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL ++ LGTP E + + N +AR Y+ ++ K + + ++FP A +AL LL+R
Sbjct: 302 VHQLDIMTDFLGTP-PPEAISKIRNDKARRYLGNMRKKQPVPFSKKFPKADPSALRLLER 360
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
++ FDP+ R +A EAL+ PY EP PI F+F+ + +L D++ L++
Sbjct: 361 LIAFDPKDRPSAEEALADPYFNGLSSKVREPSTQPISKLEFEFE--RKKLTKDDIRELIY 418
Query: 367 NEIV 370
EI+
Sbjct: 419 REIL 422
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 260 bits (664), Expect = 3e-69
Identities = 141/355 (39%), Positives = 209/355 (58%), Gaps = 39/355 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GAYG VCSA +G VAIKK+ PF+ LF+ R RE+++LKH +HEN+I + DV
Sbjct: 33 VGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDV 92
Query: 78 QKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
P + + F + Y++ M TDL +++ ++L ED +Q+ VYQ L+ L+ +H + +IHR
Sbjct: 93 FTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHR 152
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NL +N +C+LKI DFGLAR A S
Sbjct: 153 DLKPGNLAVNEDCELKILDFGLAR-------------------------------QADSE 181
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT YV TRWYRAPEV+L +Y++++D+WS GCI+AE++ + LF G D+ DQL I +
Sbjct: 182 MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKV 241
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
GTP E V+ +++ A+ ++ LP+ K ++ NAS A++LL++ML D R+
Sbjct: 242 TGTP-PAEFVQRLQSDEAKNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV 300
Query: 317 TATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWNEIVS 371
TA EAL+HPY S HD +DEP+ SF D+ + KR+ + E++S
Sbjct: 301 TAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDR-----TLDEWKRVTYKEVLS 350
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 259 bits (662), Expect = 4e-69
Identities = 143/362 (39%), Positives = 221/362 (60%), Gaps = 31/362 (8%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
+S++Q+Q ++G+G+YGVV SA+ +G VAIKK+ FE +IR LREIK+L+ +H
Sbjct: 13 ASQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRH 72
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSEDHVQYFVYQTLRALKV 127
+I+ I + P ++F ++Y++ ELM++DLH V+ V +L+ H Q+F+YQ LR LK
Sbjct: 73 PDIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVNDDLTPQHHQFFLYQLLRGLKF 132
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H ++V HRDLKP N+L N++C +KICD GLAR+ +SPS+
Sbjct: 133 MHSAHVFHRDLKPKNILANADCKIKICDLGLARV----------------SFTDSPSAVF 176
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLT-AAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
T+YVATRWYRAPE+ + + Y+ ++D+WS GCI AE+L +PLFPGK+
Sbjct: 177 ---------WTDYVATRWYRAPELCGSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNV 227
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
QL L+ LGTP+ L + N +AR+Y+ ++ + + + +FPN AL LL R
Sbjct: 228 VHQLELVTDLLGTPSPITL-SRIRNEKARKYLGNMRRKDPVPFTHKFPNIDPVALKLLQR 286
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLW 366
++ FDP+ R +A EAL+ PY + D EP PI F+F+ + +L D++ L++
Sbjct: 287 LIAFDPKDRPSAEEALADPYFQGLANVDYEPSRQPISKLEFEFE--RRKLTRDDVRELMY 344
Query: 367 NE 368
E
Sbjct: 345 RE 346
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 245 bits (626), Expect = 7e-65
Identities = 127/296 (42%), Positives = 187/296 (62%), Gaps = 34/296 (11%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKI 62
+ ++ + +Q S +G GAYG VC+A +G VA+KK+ PF+ + + RT RE+++
Sbjct: 15 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 63 LKHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQT 121
LKH +HEN+I + DV P+ S E+FN+VY++ LM DL+ ++ Q+L++DHVQ+ +YQ
Sbjct: 75 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQI 134
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H +++IHRDLKPSNL +N +C+LKI DFGLAR +
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE---------------- 178
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
MT YVATRWYRAPE+ML Y++++D+WS GCI+AELL + LF
Sbjct: 179 ---------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 223
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNAS 297
PG D+ DQL LI + +GTP EL++ + + AR YI+SL + PK+N+ F A+
Sbjct: 224 PGTDHIDQLKLILRLVGTP-GAELLKKISSESARNYIQSLTQMPKMNFANVFIGAN 278
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 244 bits (624), Expect = 1e-64
Identities = 150/401 (37%), Positives = 210/401 (51%), Gaps = 82/401 (20%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
LGEGAYGVVC+A+++P+G+ VAIKK PF+ + + RT RE+K+L+ QH+N++ + DV
Sbjct: 55 LGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDV 114
Query: 78 QKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVL-------- 128
P N VY + LM +DL ++ Q L+++ +Q +YQ LR LK +
Sbjct: 115 FTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYMSHQNFNST 174
Query: 129 ---------------------HGSNVIHRDLKPSNLLLNSNCDLK--------------- 152
H + +IHRDLKPSN+ +N C++K
Sbjct: 175 IILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQLSFLILSF 234
Query: 153 --ICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPE 210
I DFGLAR A D + MT YVATRWYRAPE
Sbjct: 235 FKILDFGLAR--------------------------AQDAE-----MTGYVATRWYRAPE 263
Query: 211 VMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVE 270
+ML Y++++DVWS GCILAEL+ +PLFPG D+ DQL I +GTP E E ++
Sbjct: 264 IMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKE-EFWSKIQ 322
Query: 271 NRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSY 330
+ AR YI++ + ++ FP AS AL+LL+ ML DP RI+ + AL H YL Y
Sbjct: 323 SEEARNYIKNRSPIIRQDFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREY 382
Query: 331 HDPDDEPEG-TPIPSSFFQFDQWKSRLNT-KDLKRLLWNEI 369
P+DEP + +S D + R T D + L+WNEI
Sbjct: 383 SVPNDEPVAMDTVINSIVTIDPAEERATTLSDWRELIWNEI 423
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 243 bits (620), Expect = 3e-64
Identities = 143/338 (42%), Positives = 205/338 (60%), Gaps = 35/338 (10%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEI--VAIKKI-EPFEKPLFSIRTLREIKIL 63
F ++ F L +G G++ ++CS+ + S E VAI+KI F L RTLRE+K+L
Sbjct: 17 FILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLL 76
Query: 64 KHFQ-HENIISIFD---VQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSED-HVQYFV 118
+H + H NI+ +FD V P+ N VY+ +ELM+ DL ++I +++ ED H Q F+
Sbjct: 77 RHLRGHPNIVWLFDTDIVFYPNG--ALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFI 134
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXX 178
YQ L ALK +H +NV+H DLKP NLL+NS+C LKIC+FGL+ SE
Sbjct: 135 YQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSE-------------- 180
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
+ NDG I G Y+ + WY+APE++L + +K++D+WS GCILAELLG++
Sbjct: 181 -----NHKVNDG--FIKG---YITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRK 230
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA 298
P+F GKDY D L I Q LGTP E+ L E + +++ YI P ++ P A+
Sbjct: 231 PMFEGKDYVDHLNHILQILGTPPEETLQE-IASQKVYNYIFQFGNIPGRSFESILPGANP 289
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDE 336
AL+LL +ML+FDP+ RIT +AL HPYL +HD D+E
Sbjct: 290 EALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEE 327
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 239 bits (609), Expect = 6e-63
Identities = 134/322 (41%), Positives = 193/322 (59%), Gaps = 31/322 (9%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQ 67
+ + Q +G GA+GVV + G VA+KK+ F+ + S R RE+K+L F+
Sbjct: 36 VPQDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFK 95
Query: 68 HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALK 126
HEN++S D+ +P + F E+Y+I EL+Q+DLH++IV+ Q LS DH++ F+YQ LR LK
Sbjct: 96 HENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLK 155
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
LH + ++HRD+KP NLL+NSNC LKICDFGLAR+ P A
Sbjct: 156 YLHSARILHRDIKPGNLLVNSNCVLKICDFGLARV-------------------EEPDQA 196
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+ MT+ V T++YRAPE+++ A YS ++DVWS GCI ELLG++ LF ++
Sbjct: 197 KH--------MTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNP 248
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLD 305
QL LI + LGTPT +++ E R +R PK P + +A+ A+ LL
Sbjct: 249 VQQLELITELLGTPTMEDMRHACEGART-HMLRRAPKPPSFSVLYTLSSHATHEAVHLLC 307
Query: 306 RMLQFDPRLRITATEALSHPYL 327
+ML FDP RI+ T+AL+HPYL
Sbjct: 308 QMLVFDPDKRISVTDALAHPYL 329
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 235 bits (600), Expect = 7e-62
Identities = 127/321 (39%), Positives = 188/321 (58%), Gaps = 23/321 (7%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GAYGVVC A + + VAIKKI F + R+LRE++IL+ HENII++ D+
Sbjct: 63 VGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENIIAVLDM 122
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
++Y++ +LM+TDLH+++ + Q L E H QYF YQ LR LK LH + +IHR
Sbjct: 123 FTAEGAHG-KDIYLVMDLMETDLHQILHSRQTLMEQHFQYFFYQLLRGLKYLHSAGIIHR 181
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKPSNLLLN +C L+I DFG+AR + +S D
Sbjct: 182 DLKPSNLLLNGDCLLRIADFGMARAYAS-------------------ASTVRDDANVGGH 222
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT+YV+TRWYRAPE++ + +Y +D+WS GCI AE+L ++ LFPGKD Q+ +I
Sbjct: 223 MTQYVSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYY 282
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LG+P E+E++ + + R+ I + + + + FP AS A +++ +LQ P R
Sbjct: 283 LGSP-EEEVINRITSDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRY 341
Query: 317 TATEALSHPYLVSYHDPDDEP 337
+A + L HP++ YH+ EP
Sbjct: 342 SADQILQHPFMAQYHNDQYEP 362
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 231 bits (588), Expect = 2e-60
Identities = 126/333 (37%), Positives = 194/333 (57%), Gaps = 27/333 (8%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHF 66
+I +F LQ LG+GAYG+V A K S E VA+KKI + F P S RT RE+ L+ F
Sbjct: 8 HIHEKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEF 67
Query: 67 -QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSED-HVQYFVYQTLRA 124
+H N+I ++++ + + ++Y+ E M+ DLH VI + +D H QY + Q RA
Sbjct: 68 GKHPNVIKLYNIFRA---DNDRDIYLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRA 124
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
++ LH NV+HRDLKPSN+LL+++C +K+ DFGLAR +S S
Sbjct: 125 IRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLS--------------------S 164
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
+ +TEYVATRWYR+PE++L A +Y+K +D+WS GCILAE+L + LFPG
Sbjct: 165 LEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGS 224
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
+Q+ I T+ P+ ++ + + A + +P+ P+ + AA+D++
Sbjct: 225 STINQIERIMNTIAKPSRADIAS-IGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMV 283
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
R+L F P+ R+T + L HPY+V +H+P +EP
Sbjct: 284 QRLLIFAPQKRLTVEQCLVHPYVVQFHNPSEEP 316
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 228 bits (582), Expect = 8e-60
Identities = 119/247 (48%), Positives = 159/247 (64%), Gaps = 26/247 (10%)
Query: 96 MQTDLHRVI-VTQELSEDHVQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKIC 154
M++DLH++I +Q L+ +HV+YF+YQ LR LK +H + VIHRDLKPSNLL+N NC+LKI
Sbjct: 1 MESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIG 60
Query: 155 DFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLT 214
DFG+AR + SP+ MTEYVATRWYRAPE+ML+
Sbjct: 61 DFGMARGLC-----------------TSPAEHQYF-------MTEYVATRWYRAPELMLS 96
Query: 215 AAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRA 274
+Y++++D+WS GCI E+L ++ LFPGK+Y QL LI LGTP+ +++ V R
Sbjct: 97 LHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPS-PAVIQAVGAERV 155
Query: 275 REYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPD 334
R YI+SLP + W +P A AL LL RML+F+P RI+A AL HP+L YHDPD
Sbjct: 156 RAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPD 215
Query: 335 DEPEGTP 341
DEP+ P
Sbjct: 216 DEPDCAP 222
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 228 bits (581), Expect = 1e-59
Identities = 131/312 (41%), Positives = 188/312 (59%), Gaps = 31/312 (9%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSI-RTLREIKILKHFQHENIISIFDV 77
+G GA+GVV S G+ VA+KK+ + L S R RE+K+L F+H+N++S D+
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDI 191
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+P + F E+Y++ ELMQ+DLH++IV+ Q LS DHV+ F+YQ LR LK LH + ++HR
Sbjct: 192 LQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHR 251
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP NLL+NSNC LKICDFGLAR+ + D +
Sbjct: 252 DIKPGNLLVNSNCVLKICDFGLARV--------------------------EELDES-RH 284
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT+ V T++YRAPE+++ + YS ++D+WS GCI AELLG++ LF + QL LI
Sbjct: 285 MTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDL 344
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-ASAAALDLLDRMLQFDPRLR 315
LGTP+ + + E +A +R K P + + A+ A+ LL RML FDP R
Sbjct: 345 LGTPSLEAMRTACEGAKA-HILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKR 403
Query: 316 ITATEALSHPYL 327
I+A +AL+HPYL
Sbjct: 404 ISAKDALAHPYL 415
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 227 bits (579), Expect = 2e-59
Identities = 115/267 (43%), Positives = 169/267 (63%), Gaps = 33/267 (12%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKI 62
+ ++ + +Q S +G GAYG VC+A +G VA+KK+ PF+ + + RT RE+++
Sbjct: 15 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 74
Query: 63 LKHFQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQT 121
LKH +HEN+I + DV P+ S E+FN+VY++ LM DL+ ++ Q+L++DHVQ+ +YQ
Sbjct: 75 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQI 134
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
LR LK +H +++IHRDLKPSNL +N +C+LKI DFGLAR +
Sbjct: 135 LRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE---------------- 178
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
MT YVATRWYRAPE+ML Y++++D+WS GCI+AELL + LF
Sbjct: 179 ---------------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 223
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVEL 268
PG D+ DQL LI + +GTP + L ++
Sbjct: 224 PGTDHIDQLKLILRLVGTPGAELLKKI 250
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 223 bits (569), Expect = 3e-58
Identities = 129/314 (41%), Positives = 189/314 (60%), Gaps = 33/314 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSI-RTLREIKILKHFQHENIISIFDV 77
+G GA+GVV S SG+ VA+KK+ + L S R REIK+L F+H+N++S+ D+
Sbjct: 49 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDI 108
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+P++ F E+Y++ ELMQ+DLH++IV+ Q L+ DHV+ FVYQ LR LK LH +N++HR
Sbjct: 109 LQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILHR 168
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP NLL+NSNC LKICDFGLAR +R
Sbjct: 169 DIKPGNLLVNSNCILKICDFGLARTWDQRDRL---------------------------N 201
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT V T++YRAPE+++ A +Y+ ++D+WS GCI AELL ++ LF +QL +I
Sbjct: 202 MTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDL 261
Query: 257 LGTPTEQEL---VELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPR 313
LGTP+++ + E +N R +R+ P ++ + + A+DLL ++L FDP
Sbjct: 262 LGTPSQEAMKYACEGAKNHVLRAGLRA-PDTQRLYKIASPDDKNHEAVDLLQKLLHFDPD 320
Query: 314 LRITATEALSHPYL 327
RI+ EAL H YL
Sbjct: 321 KRISVEEALQHRYL 334
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 223 bits (569), Expect = 3e-58
Identities = 129/314 (41%), Positives = 189/314 (60%), Gaps = 33/314 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSI-RTLREIKILKHFQHENIISIFDV 77
+G GA+GVV S SG+ VA+KK+ + L S R REIK+L F+H+N++S+ D+
Sbjct: 74 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDI 133
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+P++ F E+Y++ ELMQ+DLH++IV+ Q L+ DHV+ FVYQ LR LK LH +N++HR
Sbjct: 134 LQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILHR 193
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP NLL+NSNC LKICDFGLAR +R
Sbjct: 194 DIKPGNLLVNSNCILKICDFGLARTWDQRDRL---------------------------N 226
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT V T++YRAPE+++ A +Y+ ++D+WS GCI AELL ++ LF +QL +I
Sbjct: 227 MTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDL 286
Query: 257 LGTPTEQEL---VELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPR 313
LGTP+++ + E +N R +R+ P ++ + + A+DLL ++L FDP
Sbjct: 287 LGTPSQEAMKYACEGAKNHVLRAGLRA-PDTQRLYKIASPDDKNHEAVDLLQKLLHFDPD 345
Query: 314 LRITATEALSHPYL 327
RI+ EAL H YL
Sbjct: 346 KRISVEEALQHRYL 359
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 223 bits (569), Expect = 3e-58
Identities = 129/314 (41%), Positives = 189/314 (60%), Gaps = 33/314 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSI-RTLREIKILKHFQHENIISIFDV 77
+G GA+GVV S SG+ VA+KK+ + L S R REIK+L F+H+N++S+ D+
Sbjct: 246 IGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDI 305
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+P++ F E+Y++ ELMQ+DLH++IV+ Q L+ DHV+ FVYQ LR LK LH +N++HR
Sbjct: 306 LQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILHR 365
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP NLL+NSNC LKICDFGLAR +R
Sbjct: 366 DIKPGNLLVNSNCILKICDFGLARTWDQRDRL---------------------------N 398
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
MT V T++YRAPE+++ A +Y+ ++D+WS GCI AELL ++ LF +QL +I
Sbjct: 399 MTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDL 458
Query: 257 LGTPTEQEL---VELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPR 313
LGTP+++ + E +N R +R+ P ++ + + A+DLL ++L FDP
Sbjct: 459 LGTPSQEAMKYACEGAKNHVLRAGLRA-PDTQRLYKIASPDDKNHEAVDLLQKLLHFDPD 517
Query: 314 LRITATEALSHPYL 327
RI+ EAL H YL
Sbjct: 518 KRISVEEALQHRYL 531
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 223 bits (569), Expect = 3e-58
Identities = 127/320 (39%), Positives = 187/320 (57%), Gaps = 20/320 (6%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQH 68
++++ Q LG GA+GVVC A + VAIKKI F+ + LREI+I + H
Sbjct: 41 ATQYLAQENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITRELSH 100
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKV 127
ENII+ DV S ++YI+ +LM+TDL V+ + Q L+E H QYF YQ L+ LK
Sbjct: 101 ENIINSTDVLMRESGSG-QDIYIVMDLMETDLLSVLKSNQTLNEKHFQYFFYQILKGLKY 159
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
LH + +IHRDLKP+NLLLN +C LKI DFG++R N+ +A
Sbjct: 160 LHSAGIIHRDLKPANLLLNEDCSLKIADFGMSR-----------SGPSTKTTPNTSPNAH 208
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYR 247
GD +++YV+T WYRAPE++L+ +Y +D+WS GCILAE+L +P+F G D
Sbjct: 209 ISGD-----LSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSY 263
Query: 248 DQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRM 307
Q+ L+ + LGTP EQ ++ +++ R+YI S + + FPNAS A +++ +M
Sbjct: 264 SQIQLLIEYLGTPDEQ-VIRRIKSPSIRDYISSFGPKTPLPFTAMFPNASIEARNIVSKM 322
Query: 308 LQFDPRLRITATEALSHPYL 327
LQ P R +A + L P++
Sbjct: 323 LQISPWKRFSAEQLLEEPFV 342
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 221 bits (564), Expect = 1e-57
Identities = 138/358 (38%), Positives = 203/358 (56%), Gaps = 33/358 (9%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHK---PSGEIVAIKKIEP-FEKPLFSIRTLREIKIL 63
+I +++ LG+GAYG VCS K K P+ I A+KKI F K + R +RE+K +
Sbjct: 33 SIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARI-AVKKISNIFNKEILLKRAIRELKFM 91
Query: 64 KHFQ-HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ-ELSEDHVQYFVYQT 121
F+ H+NI+++ D++ +S ++ +Y QEL+ DL +VI + +LSE H++YF+YQ
Sbjct: 92 NFFKGHKNIVNLIDLEIVTS-SPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQI 150
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
L LK +H ++VIHRDLKP N+L N LKICDFGLAR +
Sbjct: 151 LCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFF-------------- 196
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
+ P I T YVATRWYRAPE++L+ YSKS+D+W+ GCILAE ++P+F
Sbjct: 197 ---KCHSTVQPHI---TNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVF 250
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRS-LPKHPKINWRRRFPNASAAA 300
G+D Q+ I + LGTP + L++ + S P + KI W FP AS A
Sbjct: 251 MGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEA 310
Query: 301 LDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNT 358
++L++ +L +D R+ +A+SHP+L PDDEP P F ++S LN+
Sbjct: 311 INLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDF----TYESELNS 364
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 221 bits (562), Expect = 2e-57
Identities = 135/378 (35%), Positives = 205/378 (53%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A G VA+KK+ PF+ + R RE+ +LK
Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+AE++ + LFPG+
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMAEMVLHKVLFPGR 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN--------- 295
DY DQ + + LGTP+ + + +L R Y+ + PK+P I + FP+
Sbjct: 229 DYIDQWNKVIEQLGTPSAEFMKKL--QPTVRNYVENRPKYPGIKFEELFPDWIFPSESER 286
Query: 296 ---ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ EAL HPY+ ++DP E E P Q ++
Sbjct: 287 DKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHAI--EEWKELIYKEVM 361
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 221 bits (562), Expect = 2e-57
Identities = 135/378 (35%), Positives = 205/378 (53%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A G VA+KK+ PF+ + R RE+ +LK
Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+AE++ + LFPG+
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMAEMVLHKVLFPGR 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN--------- 295
DY DQ + + LGTP+ + + +L R Y+ + PK+P I + FP+
Sbjct: 229 DYIDQWNKVIEQLGTPSAEFMKKL--QPTVRNYVENRPKYPGIKFEELFPDWIFPSESER 286
Query: 296 ---ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ EAL HPY+ ++DP E E P Q ++
Sbjct: 287 DKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHAI--EEWKELIYKEVM 361
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 214 bits (544), Expect = 2e-55
Identities = 131/379 (34%), Positives = 204/379 (53%), Gaps = 50/379 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 176
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 177 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 219
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ + LFPG+
Sbjct: 220 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGR 266
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
DY DQ + + LGTP + + +L R Y+ + PK+ + + + FP++
Sbjct: 267 DYIDQWNKVIEQLGTPCPEFMKKL--QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEH 324
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ +AL HPY+ ++DP E E P Q D+
Sbjct: 325 NKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDKQLDER 383
Query: 353 KSRLNTKDLKRLLWNEIVS 371
+ + ++ K L++ E+++
Sbjct: 384 EHTI--EEWKELIYKEVMN 400
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 214 bits (544), Expect = 2e-55
Identities = 131/379 (34%), Positives = 204/379 (53%), Gaps = 50/379 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 176
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 177 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 219
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ + LFPG+
Sbjct: 220 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGR 266
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
DY DQ + + LGTP + + +L R Y+ + PK+ + + + FP++
Sbjct: 267 DYIDQWNKVIEQLGTPCPEFMKKL--QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEH 324
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ +AL HPY+ ++DP E E P Q D+
Sbjct: 325 NKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDKQLDER 383
Query: 353 KSRLNTKDLKRLLWNEIVS 371
+ + ++ K L++ E+++
Sbjct: 384 EHTI--EEWKELIYKEVMN 400
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 214 bits (544), Expect = 2e-55
Identities = 131/379 (34%), Positives = 204/379 (53%), Gaps = 50/379 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ + LFPG+
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGR 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
DY DQ + + LGTP + + +L R Y+ + PK+ + + + FP++
Sbjct: 229 DYIDQWNKVIEQLGTPCPEFMKKL--QPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEH 286
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ +AL HPY+ ++DP E E P Q D+
Sbjct: 287 NKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDP-AEVEAPPPQIYDKQLDER 345
Query: 353 KSRLNTKDLKRLLWNEIVS 371
+ + ++ K L++ E+++
Sbjct: 346 EHTI--EEWKELIYKEVMN 362
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 212 bits (539), Expect = 8e-55
Identities = 132/378 (34%), Positives = 201/378 (52%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A G VA+KK+ PF+ + R RE+ +LK
Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ EL+ +F G
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGT 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN--------- 295
D+ DQ + + LGTP+ + + +L R Y+ + PK+P I + FP+
Sbjct: 229 DHIDQWNKVIEQLGTPSAEFMKKL--QPTVRNYVENRPKYPGIKFEELFPDWIFPSESER 286
Query: 296 ---ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ EAL HPY+ ++DP E E P Q ++
Sbjct: 287 DKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHAI--EEWKELIYKEVM 361
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 212 bits (539), Expect = 8e-55
Identities = 132/378 (34%), Positives = 201/378 (52%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A G VA+KK+ PF+ + R RE+ +LK
Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ EL+ +F G
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGT 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN--------- 295
D+ DQ + + LGTP+ + + +L R Y+ + PK+P I + FP+
Sbjct: 229 DHIDQWNKVIEQLGTPSAEFMKKL--QPTVRNYVENRPKYPGIKFEELFPDWIFPSESER 286
Query: 296 ---ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ EAL HPY+ ++DP E E P Q ++
Sbjct: 287 DKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHAI--EEWKELIYKEVM 361
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 212 bits (539), Expect = 8e-55
Identities = 132/378 (34%), Positives = 201/378 (52%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A G VA+KK+ PF+ + R RE+ +LK
Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NIIS+ +V P + E+F +VY++ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVI-HMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ EL+ +F G
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGELVKGCVIFQGT 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN--------- 295
D+ DQ + + LGTP+ + + +L R Y+ + PK+P I + FP+
Sbjct: 229 DHIDQWNKVIEQLGTPSAEFMKKL--QPTVRNYVENRPKYPGIKFEELFPDWIFPSESER 286
Query: 296 ---ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML DP RI+ EAL HPY+ ++DP E E P Q ++
Sbjct: 287 DKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDP-AEAEAPPPQIYDAQLEER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHAI--EEWKELIYKEVM 361
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 211 bits (536), Expect = 2e-54
Identities = 132/378 (34%), Positives = 200/378 (51%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NII + +V P S E+F +VYI+ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ + LFPG+
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGR 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
DY DQ + + LGTP + + +L R Y+ + PK+ ++ + FP+
Sbjct: 229 DYIDQWNKVIEQLGTPCPEFMKKL--QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEH 286
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML D RI+ EAL HPY+ ++DP E E P Q D+
Sbjct: 287 NKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHTI--EEWKELIYKEVM 361
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 211 bits (536), Expect = 2e-54
Identities = 132/378 (34%), Positives = 200/378 (51%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NII + +V P S E+F +VYI+ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ + LFPG+
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDLWSVGCIMGEMVCHKILFPGR 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
DY DQ + + LGTP + + +L R Y+ + PK+ ++ + FP+
Sbjct: 229 DYIDQWNKVIEQLGTPCPEFMKKL--QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEH 286
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML D RI+ EAL HPY+ ++DP E E P Q D+
Sbjct: 287 NKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHTI--EEWKELIYKEVM 361
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 209 bits (532), Expect = 5e-54
Identities = 136/392 (34%), Positives = 202/392 (50%), Gaps = 56/392 (14%)
Query: 1 MGKRIVFNISSEFQLQ----SLLGEGAYGVVCSAK---HKPSGEIVAIKKI-EPFEKPLF 52
M + I F I + ++ LG G++G V VAIKK+ EPF P
Sbjct: 102 MIRNITFAIPEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHH 161
Query: 53 SIRTLREIKILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE---- 108
+ R RE K+L+ +H+NII D+ P F +VY++ E L++++ Q
Sbjct: 162 ARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGR 221
Query: 109 --LSEDHVQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERX 166
L+++H+++ +YQ +RALK +H +N+IHRDLKP NL L + DL I DFGLAR + ++
Sbjct: 222 RVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKD 281
Query: 167 XXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQ-YSKSMDVW 225
+ +T+YV TRWYR+PEV+ Y+ D+W
Sbjct: 282 ----------------------------TSLTQYVQTRWYRSPEVIYWKIDSYTNLADMW 313
Query: 226 SCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRA---REYIRSLP 282
S GCI AELL +PLFPG + Q I Q G+P E EL+ +EN + + I+S
Sbjct: 314 SLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDE-ELLTKIENDNSSAIKAVIQSYT 372
Query: 283 KHPKINWRRRFP--NASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGT 340
H + N+R F N S +DLL+++L DP RIT EA+ HPYL + P+DEP
Sbjct: 373 THKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLAEFSLPEDEPRAD 432
Query: 341 PIPSSFFQFDQWKSRLNTK-DLKRLLWNEIVS 371
I FD S+ T+ + + +W EI++
Sbjct: 433 HI------FDLDDSQARTRFEWRDAVWKEIMN 458
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 208 bits (529), Expect = 1e-53
Identities = 131/378 (34%), Positives = 198/378 (51%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NII + +V P S E+F +VYI+ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ LFPG
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGT 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
D+ DQ + + LGTP + + +L R Y+ + PK+ ++ + FP+
Sbjct: 229 DHIDQWNKVIEQLGTPCPEFMKKL--QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEH 286
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML D RI+ EAL HPY+ ++DP E E P Q D+
Sbjct: 287 NKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHTI--EEWKELIYKEVM 361
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 208 bits (529), Expect = 1e-53
Identities = 131/378 (34%), Positives = 198/378 (51%), Gaps = 50/378 (13%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F + +Q +G GA G+VC+A VAIKK+ PF+ + R RE+ ++K
Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NII + +V P S E+F +VYI+ ELM +L +VI EL + + Y +YQ L
Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVI-QMELDHERMSYLLYQMLCG 138
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ S+C LKI DFGLAR
Sbjct: 139 IKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFM----------------- 181
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y +++D+WS GCI+ E++ LFPG
Sbjct: 182 ------------MTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMIKGGVLFPGT 228
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
D+ DQ + + LGTP + + +L R Y+ + PK+ ++ + FP+
Sbjct: 229 DHIDQWNKVIEQLGTPCPEFMKKL--QPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEH 286
Query: 297 ----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQW 352
++ A DLL +ML D RI+ EAL HPY+ ++DP E E P Q D+
Sbjct: 287 NKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDP-SEAEAPPPKIPDKQLDER 345
Query: 353 KSRLNTKDLKRLLWNEIV 370
+ + ++ K L++ E++
Sbjct: 346 EHTI--EEWKELIYKEVM 361
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 205 bits (521), Expect = 1e-52
Identities = 129/344 (37%), Positives = 186/344 (53%), Gaps = 44/344 (12%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF 66
F++ S + LG G G+V SA + VAIKKI P LREIKI++
Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIV-LTDPQSVKHALREIKIIRRL 72
Query: 67 QHENIISIFDVQKPS---------SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYF 117
H+NI+ +F++ PS S + N VYI+QE M+TDL V+ L E+H + F
Sbjct: 73 DHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLF 132
Query: 118 VYQTLRALKVLHGSNVIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXX 176
+YQ LR LK +H +NV+HRDLKP+NL +N+ + LKI DFGLARI+
Sbjct: 133 MYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIM-------------- 178
Query: 177 XXXXNSPSSAANDGDPAIS---GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAE 233
DP S ++E + T+WYR+P ++L+ Y+K++D+W+ GCI AE
Sbjct: 179 --------------DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAE 224
Query: 234 LLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF 293
+L + LF G +Q+ LI +++ E++ EL+ YIR+ P +
Sbjct: 225 MLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLS--VIPVYIRNDMTEPHKPLTQLL 282
Query: 294 PNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
P S ALD L+++L F P R+TA EALSHPY+ Y P DEP
Sbjct: 283 PGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEP 326
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 204 bits (518), Expect = 2e-52
Identities = 138/385 (35%), Positives = 196/385 (50%), Gaps = 53/385 (13%)
Query: 2 GKRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREI 60
G F I + + S L GA G V A + + VAIKK++ PF + + R RE
Sbjct: 27 GADSTFTIPTRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREF 86
Query: 61 KILKHFQHENIISIFDVQKP-SSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVY 119
+L +H NII + + P +S F EVY++ ELM +LH VI L + +FVY
Sbjct: 87 ILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDHKTLSFFVY 146
Query: 120 QTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXX 179
Q+L A+K LH S VIHRDLKPSN+++N C LK+ DFGLAR
Sbjct: 147 QSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLAR------------------K 188
Query: 180 XNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
N +S M++YV TR+YRAPEV+L YS+ +D+WS GCI AE++
Sbjct: 189 KNVDTSMR---------MSDYVVTRYYRAPEVIL-GLPYSEKVDIWSVGCIFAEMINHTV 238
Query: 240 LFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKH---------PKINWR 290
LFPGKD DQ I+ LGTP + + +L + A Y+RSLP+H P N+
Sbjct: 239 LFPGKDRIDQWTKIYSVLGTPDDHFISQL--GQSAAMYVRSLPRHQARAFSEIVPDTNFL 296
Query: 291 RRFPNASA-----AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
N A DLL ML+ +P R + +AL+HPY+ + D+ P+S
Sbjct: 297 PETENPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYVKLWFKDDE----VNAPAS 352
Query: 346 FFQFDQWKSRLNTKDLKRLLWNEIV 370
++DQ ++ D + W E++
Sbjct: 353 ENRYDQ---EIDFADKTLIEWKELI 374
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 202 bits (514), Expect = 6e-52
Identities = 127/349 (36%), Positives = 179/349 (50%), Gaps = 47/349 (13%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQ 67
+ +Q L+G GA G+VCSA E VAIKK+ PF+ + R RE+K++
Sbjct: 115 VLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVN 174
Query: 68 HENIISIFDVQKPSS-FEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALK 126
H+NII I + P ++FN++YI+ ELM +L +VI +L + + Y +YQ L ++
Sbjct: 175 HKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVI-QMDLDHERLSYLLYQMLCGIR 233
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
LH + +IHRDLKPSN+++ S+C LKI DFGLAR E
Sbjct: 234 HLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFM------------------- 274
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
MT YV TR+YRAPEV+L Y +++DVWS GCI EL+ + LFPG D+
Sbjct: 275 ----------MTPYVVTRYYRAPEVIL-GMGYKENVDVWSIGCIFGELIRGRVLFPGGDH 323
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN----------- 295
DQ I + LGTP L L R Y+ + P++ + F +
Sbjct: 324 IDQWTRIIEQLGTPDRSFLERL--QPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSR 381
Query: 296 -ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIP 343
A A DLL RML DP RI+ +AL HPY+ + D + P+P
Sbjct: 382 LTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIEVYAPPPLP 430
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 201 bits (511), Expect = 1e-51
Identities = 126/368 (34%), Positives = 189/368 (51%), Gaps = 54/368 (14%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH 65
F I S + +G GA G+VC+A + + VAIKK+ PF+ + R RE K++K
Sbjct: 18 FTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKL 77
Query: 66 FQHENIISIFDVQKPS-SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
H+NII + + P + E+F +VY++ ELM +L +VI +L D + Y +YQ L
Sbjct: 78 VNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVI-QMDLDHDRMSYLLYQMLCG 136
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+K LH + +IHRDLKPSN+++ ++C LKI DFGLAR
Sbjct: 137 IKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFM----------------- 179
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
MT YV TR+YRAPEV+L Y++++D+WS GCI+ E++ LFPG
Sbjct: 180 ------------MTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMIRGGVLFPGT 226
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA-------- 296
D+ DQ I + LGTP+ + L R Y+ + P++ ++ R FP+
Sbjct: 227 DHIDQWNKIIEQLGTPSPSFMQRL--QPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQ 284
Query: 297 -----SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHD------PDDEPEGTPIPSS 345
++ A +LL +ML DP RI+ EAL H Y+ ++D P EP +
Sbjct: 285 NSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDER 344
Query: 346 FFQFDQWK 353
+QWK
Sbjct: 345 EHTVEQWK 352
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 199 bits (507), Expect = 4e-51
Identities = 130/324 (40%), Positives = 178/324 (54%), Gaps = 41/324 (12%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EF+ + + EG YGVV AK K +GEIVA+KK++ E+ F + +LREI IL F H +
Sbjct: 405 EFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPS 464
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+ + +V SS + ++++ E M+ DL ++ T Q S+ V+ + Q L +K L
Sbjct: 465 IVDVKEVVVGSSLDS---IFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVKYL 521
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + V+HRDLK SNLLLN+ +LKICDFGLAR
Sbjct: 522 HDNWVLHRDLKTSNLLLNNRGELKICDFGLAR---------------------------Q 554
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A QYS ++D+WS GCI+AELL K PLF GK D
Sbjct: 555 YGSP-LKPYTHLVVTLWYRAPELLLGAKQYSTAIDMWSLGCIMAELLMKAPLFNGKTEFD 613
Query: 249 QLILIFQTLGTPTE------QELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
QL IF+ LGTP E +L + N +Y K P ++ P S A D
Sbjct: 614 QLDKIFRILGTPNESIWPGFSKLPGVKVNFVKHQYNLLRKKFPATSFTGA-PVLSDAGFD 672
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
LL+++L +DP RIT EAL H +
Sbjct: 673 LLNKLLTYDPERRITVNEALKHDW 696
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 196 bits (499), Expect = 4e-50
Identities = 115/332 (34%), Positives = 181/332 (53%), Gaps = 48/332 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LG G G+V SA + VA+KKI + LREIKI++ H+NI+ +++V
Sbjct: 26 LGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK-HALREIKIIRRLDHDNIVKVYEVL 84
Query: 79 KPSSFE------QFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSN 132
P + +F+ YI+QE M+TDL R++ L+E+H + F+YQ LR LK +H +N
Sbjct: 85 GPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTLAEEHAKLFMYQLLRGLKYIHSAN 144
Query: 133 VIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGD 191
V+HRDLKP+N+ +++ + LKI DFGLARIV +
Sbjct: 145 VLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGY-------------------- 184
Query: 192 PAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLI 251
++E + T+WYR+P ++L+ Y+K++D+W+ GCILAE+L + LF G +Q+
Sbjct: 185 -----LSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQ 239
Query: 252 LIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINW------RRRFPNASAAALDLLD 305
LI +T+ E++ EL +R +P W R+ P ++ A+D L+
Sbjct: 240 LILETIPVIREEDKDEL---------LRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLE 290
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
++L F+P R+TA L HPY+ Y P+DEP
Sbjct: 291 KILTFNPMDRLTAEMGLQHPYMSPYSCPEDEP 322
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 194 bits (492), Expect = 2e-49
Identities = 110/322 (34%), Positives = 180/322 (55%), Gaps = 26/322 (8%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQ 67
+ S F ++ +G+GAYG+V A + + VA+KK+ + F + RT RE+ L+ F+
Sbjct: 21 VESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFR 80
Query: 68 -HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSED-HVQYFVYQTLRAL 125
H NI+ + D+ K S+ F Y++ E M++DLH VI + +D H ++ +YQ + A+
Sbjct: 81 CHPNIVRLVDIFKASNNLDF---YLVFEFMESDLHNVIKRGNVLKDVHKRFVMYQLINAI 137
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
K +H NVIHRDLKPSN+L++S C LK+ DFGLAR +S R
Sbjct: 138 KFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIY---------------DD 182
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
DG +T+YVATRWYRAPE+++ + Y+K +D+W GCIL E++ ++PLF G
Sbjct: 183 LEQDG-----MLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTS 237
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
+Q+ I +L T+ ++ + + + R++ + + + N + L+
Sbjct: 238 TVNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVK 297
Query: 306 RMLQFDPRLRITATEALSHPYL 327
+L +P R+TA EA+ HPY+
Sbjct: 298 ALLVLNPHNRLTAKEAIRHPYV 319
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 192 bits (487), Expect = 9e-49
Identities = 120/341 (35%), Positives = 178/341 (52%), Gaps = 37/341 (10%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPL-FSIRTLREIKILKHF 66
N ++++ + EG+YG+V K + +VA+KKI+ + F I +LREI+ L
Sbjct: 69 NSIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSI 128
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRA 124
+H+NI+ +++K + +VY++ E M+ DL ++ + ++ + V+ + Q L A
Sbjct: 129 RHDNIV---ELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAA 185
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+H +HRDLKPSNLL+N+ ++K+ DFGLAR VSE
Sbjct: 186 TAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPK------------------ 227
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
S +T V T WYRAPE++L A Y K +D+WS GCI AE++ + PLF GK
Sbjct: 228 ----------SSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGK 277
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIR-SLPKHPKINWRRRFPNASAAALDL 303
DQL IF LG PT +E + A + ++P H KI R PN + A DL
Sbjct: 278 SELDQLYKIFNLLGYPTREEWPQYFLLPYANKIKHPTVPTHSKI--RTSIPNLTGNAYDL 335
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPS 344
L+R+L +P RI+A EAL HPY P D PS
Sbjct: 336 LNRLLSLNPAKRISAKEALEHPYFYESPRPKDPKFFPTFPS 376
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 190 bits (482), Expect = 3e-48
Identities = 131/384 (34%), Positives = 187/384 (48%), Gaps = 54/384 (14%)
Query: 2 GKRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREI 60
G I F I + + L GA G+V A + + VAIKK++ PF + + R RE
Sbjct: 18 GAGITFTIPTRYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREF 77
Query: 61 KILKHFQHENIISIFDVQKP-SSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVY 119
+L +H NII + + P +S F EVY++ E M +LH VI L + + + VY
Sbjct: 78 ILLTTLKHPNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDHETLSFLVY 137
Query: 120 QTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXX 179
Q+L A+K LH IHRDLKPSN+++N C LK+ DFGLAR +
Sbjct: 138 QSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLARRRN---------------- 181
Query: 180 XNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
M++YV TR+YRAPEV+L YS+ +D+WS GCILAE++
Sbjct: 182 -------------VDMRMSDYVGTRYYRAPEVIL-GLNYSEKVDIWSVGCILAEMINHTV 227
Query: 240 LFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNAS-- 297
LFPGKD RDQ I L TP + + +L Y+RSLP+H + P+++
Sbjct: 228 LFPGKDIRDQWTQISSVLRTPDDHFINQL--EPIGAVYVRSLPQHLARAFNEIVPDSNFL 285
Query: 298 ------------AAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
A DLL ML+ +P R + +AL+HPY + D + P
Sbjct: 286 PETENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPYTMD--DEVNAPASEIPDDE 343
Query: 346 FFQFDQWKSRLNTKDLKRLLWNEI 369
D W + KRL++NE+
Sbjct: 344 VNDIDDW----TLIEWKRLIFNEV 363
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 189 bits (479), Expect = 7e-48
Identities = 112/321 (34%), Positives = 179/321 (54%), Gaps = 36/321 (11%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEK-PLFSIRTLREIKILKHF 66
N+ ++F++ ++GEGAYGVV +HK + EIVAIKK + E+ TLRE+K+L+
Sbjct: 8 NVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTL 67
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRA 124
+ ENI+ + + +F + ++Y++ E ++ ++ ++ + + + V+ ++YQ ++A
Sbjct: 68 KQENIVELKE-----AFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKA 122
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+ H ++++HRD+KP NLL++ N LK+CDFG AR +SE
Sbjct: 123 IHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSE-------------------- 162
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
G+ A TEYVATRWYR+PE++L A Y KS+D+WS GCIL EL QPLFPG+
Sbjct: 163 -----GNNA--NYTEYVATRWYRSPELLL-GAPYGKSVDMWSVGCILGELSDGQPLFPGE 214
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
DQL I + LG +++ N R HP+ RR ++ LDL+
Sbjct: 215 SEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLM 274
Query: 305 DRMLQFDPRLRITATEALSHP 325
+L+ DP R + L+HP
Sbjct: 275 KNLLKLDPADRYLTEQCLNHP 295
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 188 bits (477), Expect = 1e-47
Identities = 125/340 (36%), Positives = 171/340 (49%), Gaps = 41/340 (12%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQ 67
++ + + +LG+G YGVV A +GE VAIKKI EK ++ LREIK+LK +
Sbjct: 7 VADRYLKREVLGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELK 66
Query: 68 HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRAL 125
H +II + D +F ++I+ E M+TDL VI + L S V+ ++ L+ L
Sbjct: 67 HPHIIELID-----AFPHKENLHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMILKGL 121
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+ HG V+HRD+KP+NLL+ N LK+ DFGLARI
Sbjct: 122 EYCHGKWVLHRDMKPNNLLIGPNGQLKLADFGLARIF----------------------- 158
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G P T V RWYRAPE++ A QY ++DVW+ GCI AELL ++P G
Sbjct: 159 ----GSPG-RKFTHQVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQGNS 213
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
DQL IF GTP + +++ EY P + R P S ALDLL
Sbjct: 214 DIDQLSKIFAAFGTPKADQWPDMICLPDYVEY----QFVPAPSLRSLLPTVSEDALDLLS 269
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
+M +DP+ RI+ +AL H Y S P D P P P S
Sbjct: 270 KMFTYDPKSRISIQQALKHRYFTSAPSPTD-PLKLPRPVS 308
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 187 bits (476), Expect = 2e-47
Identities = 115/286 (40%), Positives = 161/286 (56%), Gaps = 46/286 (16%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHF- 66
I + L+ LG+GAYG+V A + +GE+VAIKKI + F + RT REI +L+ F
Sbjct: 9 IVRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFG 68
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELM-----------------QTDLHRVIVTQEL 109
H NIIS+ DV + E ++Y++ E M TDL+ VI L
Sbjct: 69 DHPNIISLLDVIRA---ENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGL 125
Query: 110 SED-HVQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXX 168
+D HV+ YQ LRA + LH +V+HRD KPSN+LL++NC +K+CDFGLAR + +
Sbjct: 126 LQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDL--- 182
Query: 169 XXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCG 228
P +TEYVATRWYRAPEV+L++ +Y+ +D+WS G
Sbjct: 183 --------------------PEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLG 222
Query: 229 CILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRA 274
CIL E+L +PLFPG QL LI +T+ P+E++L+ L RA
Sbjct: 223 CILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRA 268
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 185 bits (469), Expect = 1e-46
Identities = 127/350 (36%), Positives = 183/350 (52%), Gaps = 58/350 (16%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI----EPFEKPL-FSIRTLREIKILKH 65
+EFQ + + EG YG+V A+ + + EIVA+KKI + FE+ F + +LREI IL
Sbjct: 295 NEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLS 354
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLR 123
H I+++ +V + N+VY++ E ++ DL V+ ++ S V+ + Q L
Sbjct: 355 CNHPAIVNVKEVVVGGKND--NDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLD 412
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
LK LH + +IHRDLKPSNLL+N+ +LKICDFG+AR
Sbjct: 413 GLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMAR----------------------- 449
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
G P I T+ V T+WYR PE++L A +YS ++D+WS GCI+AELL ++PLFPG
Sbjct: 450 ----QYGSP-IKPYTQMVITQWYRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPG 504
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-------- 295
K DQL IF LGTP E A+ P P R++FP
Sbjct: 505 KSELDQLQKIFAVLGTPNEAIWPGFSSFPNAK---AKFPTQPYNMLRKKFPAISFVGGQI 561
Query: 296 ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
S DLL+ +L DP R+T +AL+H + +H+ P+P S
Sbjct: 562 LSERGFDLLNSLLTLDPEKRLTVEDALNHGW---FHE-------VPLPKS 601
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 185 bits (469), Expect = 1e-46
Identities = 123/333 (36%), Positives = 169/333 (49%), Gaps = 41/333 (12%)
Query: 16 QSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISI 74
+ +LGEG YGVV A +G+ VA+KKI +K + LREIK+LK H +I+ +
Sbjct: 16 RQILGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVEL 75
Query: 75 FDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSN 132
D +F ++++ E MQTDL VI + LS ++ ++ TL+ L H
Sbjct: 76 ID-----AFPHDGSLHLVFEYMQTDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKKW 130
Query: 133 VIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDP 192
V+HRD+KP+NLL+ N LK+ DFGLAR+ SP+
Sbjct: 131 VLHRDMKPNNLLIGENGLLKLADFGLARLFG------------------SPNRR------ 166
Query: 193 AISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLIL 252
T V WYRAPE++ + QY +DVW+ GCI AELL ++P PG DQL
Sbjct: 167 ----FTHQVFATWYRAPELLFGSRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGK 222
Query: 253 IFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDP 312
IFQ GTP + +++ E+ + P R FP AS ALDLL +M +DP
Sbjct: 223 IFQAFGTPVPSQWSDMIYLPDYMEFSYT----PAPPLRTIFPMASDDALDLLAKMFIYDP 278
Query: 313 RLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
R RIT +AL H Y S P EP IP+S
Sbjct: 279 RQRITIQQALDHRYFSSSPSP-TEPGKLQIPAS 310
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 184 bits (466), Expect = 2e-46
Identities = 115/329 (34%), Positives = 169/329 (50%), Gaps = 43/329 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENI 71
FQ +GEG YGVV AK++ +G++VA+KKI E +REI +LK +H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 72 ISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT---QELSEDHVQYFVYQTLRALKVL 128
+ + DV ++Y++ E + DL + + + EL ++ +++Q L+ +
Sbjct: 64 VRLLDV-----VHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H VIHRDLKP NLL+N +K+ DFGLAR
Sbjct: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAF-------------------------- 152
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L + Y+ ++D+WS GCI AE++ ++ LFPG D
Sbjct: 153 -GVP-LRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEID 210
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRML 308
QL IF+ LGTP+E + + +Y S PK + PN DLL ++L
Sbjct: 211 QLFRIFRMLGTPSEDTWPGVTQ---LPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLL 267
Query: 309 QFDPRLRITATEALSHPYLVSYHDPDDEP 337
Q+DP RITA AL+HPY + P+ P
Sbjct: 268 QYDPSQRITAKTALAHPY---FSSPEPSP 293
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 81 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 140
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 141 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 197
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 198 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 230
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 231 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 289
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 290 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 347
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 348 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 393
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 413 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 472
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 473 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 529
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 530 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 562
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 563 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 621
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 622 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 679
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 680 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 725
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 422 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 481
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 482 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 571
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 572 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 630
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 631 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 688
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 689 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 734
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 103 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 162
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 163 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 219
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 220 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 252
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 253 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 311
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 312 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 369
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 370 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 415
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 207 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 266
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 267 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 323
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 324 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 356
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 357 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 415
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 416 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 473
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 474 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 519
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 390 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 449
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 450 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 506
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 507 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 539
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 540 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 598
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 599 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 656
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 657 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 702
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 379 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 438
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 439 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 495
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 496 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 528
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 529 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 587
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 588 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 645
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 646 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 691
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 168 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 227
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 228 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 284
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 285 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 317
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 318 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 376
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 377 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 434
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 435 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 480
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 424 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 483
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 484 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 540
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 573
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 574 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 632
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 633 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 690
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 691 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 736
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 183 bits (465), Expect = 3e-46
Identities = 124/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 437 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 496
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 497 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 553
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 554 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 586
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPGK D
Sbjct: 587 YGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEID 645
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 646 QINKVFKDLGTPSEKIWPGYSELPAVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 703
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 704 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 749
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 182 bits (463), Expect = 5e-46
Identities = 123/337 (36%), Positives = 178/337 (52%), Gaps = 48/337 (14%)
Query: 17 SLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPL----FSIRTLREIKILKHFQHENII 72
S LGEG + V A+ + +IVA+KKI+ + + LREIKIL+ QHENII
Sbjct: 16 SFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENII 75
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHG 130
+ DV F Q + V ++ + M TDL +I + L++ +++ + TL+ L+ LH
Sbjct: 76 GLVDV-----FGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHL 130
Query: 131 SNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDG 190
+ ++HRDLKP+NLL+NS+ LKI DFGLA+ SP+
Sbjct: 131 NWILHRDLKPNNLLVNSDGILKIGDFGLAK------------------SFGSPNRI---- 168
Query: 191 DPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQL 250
T +V TRWYR+PE++ A QY +D+W+ GCILAEL+ + P PG DQL
Sbjct: 169 ------YTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQL 222
Query: 251 ILIFQTLGTPTEQELVELVENRRAREYI--RSLPKHPKINWRRRFPNASAAALDLLDRML 308
IF TLGTPTE E L + +Y+ R+ P P N F A + L+ R+
Sbjct: 223 TRIFSTLGTPTEAEWPHL---SKLHDYLQFRNFPGTPLDN---IFTAAGNDLIHLMQRLF 276
Query: 309 QFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
+P R++ EALS PY + P P+ P+PS+
Sbjct: 277 AMNPLRRVSCREALSMPYFANKPAPTVGPK-LPMPSA 312
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 182 bits (461), Expect = 9e-46
Identities = 123/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 419 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 478
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 479 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 535
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 536 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 568
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 569 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 627
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 628 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 685
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 686 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 731
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 182 bits (461), Expect = 9e-46
Identities = 123/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 422 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 481
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 482 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 538
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 571
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 572 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 630
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 631 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 688
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 689 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 734
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 182 bits (461), Expect = 9e-46
Identities = 123/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 409 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 468
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 469 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 525
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 526 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 558
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 559 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 617
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 618 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 675
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 676 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 721
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 182 bits (461), Expect = 9e-46
Identities = 123/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 418 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 477
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 478 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 534
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 535 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 567
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 568 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 626
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 627 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 684
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 685 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 730
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 182 bits (461), Expect = 9e-46
Identities = 123/356 (34%), Positives = 185/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI + QH N
Sbjct: 39 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN 98
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 99 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 155
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 156 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 188
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 189 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 247
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 248 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSDQGFDLMNKF 305
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 306 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 351
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 181 bits (460), Expect = 1e-45
Identities = 116/323 (35%), Positives = 168/323 (51%), Gaps = 44/323 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG YGVV +HK +G++VA+KKI E+ +REI +LK +H NI+S+ DV
Sbjct: 10 IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVT----QELSEDHVQYFVYQTLRALKVLHGSNV 133
Q + +Y+I E + DL + + + Q + V+ ++YQ L+ + H V
Sbjct: 70 -----LMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRV 124
Query: 134 IHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPA 193
+HRDLKP NLL++ +K+ DFGLAR G P
Sbjct: 125 LHRDLKPQNLLIDDKGTIKLADFGLARAF---------------------------GIP- 156
Query: 194 ISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILI 253
I T V T WYR+PEV+L +A+YS +D+WS G I AEL K+PLF G DQL I
Sbjct: 157 IRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRI 216
Query: 254 FQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPR 313
F+ LGTP + E+ ++Y + PK + N LDLL +ML +DP
Sbjct: 217 FRALGTPNNEVWPEV---ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPA 273
Query: 314 LRITATEALSHPYLVSYHDPDDE 336
RI+ AL+HPY ++D D++
Sbjct: 274 KRISGKMALNHPY---FNDLDNQ 293
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 181 bits (458), Expect = 2e-45
Identities = 114/325 (35%), Positives = 164/325 (50%), Gaps = 40/325 (12%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENI 71
FQ +GEG YGVV A++K +GE+VA+KKI E +REI +LK H NI
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNI 63
Query: 72 ISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSE---DHVQYFVYQTLRALKVL 128
+ + DV N++Y++ E + DL + + L+ ++ +++Q L+ L
Sbjct: 64 VKLLDV-----IHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFC 118
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H V+HRDLKP NLL+N+ +K+ DFGLAR
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-------------------------- 152
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T WYRAPE++L YS ++D+WS GCI AE++ ++ LFPG D
Sbjct: 153 -GVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEID 210
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRML 308
QL IF+TLGTP E V +Y S PK + ++ + P LL +ML
Sbjct: 211 QLFRIFRTLGTPDE---VVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQML 267
Query: 309 QFDPRLRITATEALSHPYLVSYHDP 333
+DP RI+A AL+HP+ P
Sbjct: 268 HYDPNKRISAKAALAHPFFQDVTKP 292
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 180 bits (457), Expect = 3e-45
Identities = 122/356 (34%), Positives = 184/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ E F I +LREI + QH N
Sbjct: 417 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPN 476
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 477 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 533
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 534 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 566
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 567 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 625
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 626 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSEQGFDLMNKF 683
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 684 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 729
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 180 bits (457), Expect = 3e-45
Identities = 122/356 (34%), Positives = 184/356 (51%), Gaps = 47/356 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ E F I +LREI + QH N
Sbjct: 419 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQHPN 478
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT--QELSEDHVQYFVYQTLRALKVL 128
I+++ ++ S+ ++ +YI+ ++ DL ++ T Q V+ + Q LR +K L
Sbjct: 479 IVTVREIVVGSNMDK---IYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL 535
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 536 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---------------------------E 568
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + T V T+WYRAPE++L A +YS ++D+WS GCI ELL ++PLFPG D
Sbjct: 569 YGSP-LKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 627
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRM 307
Q+ +F+ LGTP+E+ E ++ + +HP N R+RF S DL+++
Sbjct: 628 QINKVFKELGTPSEKIWPGYSELPVVKK--MTFSEHPYNNLRKRFGALLSEQGFDLMNKF 685
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
L + P RI+A + L H Y TP+P F W ++ + +KR
Sbjct: 686 LTYFPGRRISAEDGLKHEYF----------RETPLPIDPSMFPTWPAKSEQQRVKR 731
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 179 bits (454), Expect = 6e-45
Identities = 113/321 (35%), Positives = 165/321 (51%), Gaps = 40/321 (12%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+Q LGEG Y V +++ +GEIVA+K I +REI ++K +H NI+
Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIM 62
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ----ELSEDHVQYFVYQTLRALKVL 128
S+ DV + N++ ++ E M+ DL + + T L V+ F Q L+ +
Sbjct: 63 SLSDVLQTE-----NKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFC 117
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + V+HRDLKP NLL+NS +LK+ DFGLAR +
Sbjct: 118 HENRVLHRDLKPQNLLINSRGELKLADFGLARSI-------------------------- 151
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P ++ + V T WYRAP+V+L + YS S+D+WS GCI+AE+ +PLF G + D
Sbjct: 152 -GIP-VNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNED 209
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRML 308
QL+ IF+ LGTPTEQ + EY + P + + FP LDLL RML
Sbjct: 210 QLLKIFRLLGTPTEQSWPGI---SLLPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRML 266
Query: 309 QFDPRLRITATEALSHPYLVS 329
+ P LR T +AL H + ++
Sbjct: 267 RLQPELRTTGQDALQHAWFLT 287
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 179 bits (454), Expect = 6e-45
Identities = 116/330 (35%), Positives = 165/330 (49%), Gaps = 47/330 (14%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN- 70
+Q +GEG YGVV A+HK SG IVA+KKI E +REI +LK EN
Sbjct: 4 YQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENN 63
Query: 71 ---IISIFDVQKPSSFEQFNEVYIIQELMQTDLH----RVIVTQELSEDH--VQYFVYQT 121
+ + D+ S ++Y++ E + DL R+ T S D VQ F YQ
Sbjct: 64 RSNCVRLLDILHAES-----KLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQL 118
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
+ + H +IHRDLKP NLL++ +LK+ DFGLAR
Sbjct: 119 VNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLAR--------------------- 157
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
+ G P + T + T WYRAPEV+L + YS +D+WS GCI AE++ + PLF
Sbjct: 158 ------SFGVP-LRNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLF 210
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PG D++ IFQ LGTP E+ + ++Y + P+ +++ + PN A+
Sbjct: 211 PGDSEIDEIFKIFQVLGTPNEEVWPGVT---LLQDYKSTFPRWKRMDLHKVVPNGEEDAI 267
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYH 331
+LL ML +DP RI+A AL YL +H
Sbjct: 268 ELLSAMLVYDPAHRISAKRALQQNYLRDFH 297
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 178 bits (452), Expect = 1e-44
Identities = 116/330 (35%), Positives = 169/330 (51%), Gaps = 43/330 (13%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE----PFEKPLFSIRTLREIKILKH 65
+ ++ LGEG + V A+ K + +IVAIKKI+ K + LREIK+L+
Sbjct: 9 AKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQE 68
Query: 66 FQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLR 123
H NII + D +F + + ++ + M+TDL +I L + H++ ++ TL+
Sbjct: 69 LSHPNIIGLLD-----AFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
L+ LH ++HRDLKP+NLLL+ N LK+ DFGLA+ SP
Sbjct: 124 GLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAK------------------SFGSP 165
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+ A T V TRWYRAPE++ A Y +D+W+ GCILAELL + P PG
Sbjct: 166 NRA----------YTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPG 215
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
DQL IF+TLGTPTE++ ++ +Y+ + P I F A LDL
Sbjct: 216 DSDLDQLTRIFETLGTPTEEQWPDMCS---LPDYV-TFKSFPGIPLHHIFSAAGDDLLDL 271
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDP 333
+ + F+P RITAT+AL Y + P
Sbjct: 272 IQGLFLFNPCARITATQALKMKYFSNRPGP 301
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 176 bits (447), Expect = 4e-44
Identities = 112/322 (34%), Positives = 170/322 (52%), Gaps = 41/322 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKK-IEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG+YGVV +++ +G+IVAIKK +E + P+ LREI++LK +H N++++ +V
Sbjct: 11 IGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEV 70
Query: 78 QKPSSFEQFNEVYIIQELMQ-TDLHRVIVTQELSEDH-VQYFVYQTLRALKVLHGSNVIH 135
F + ++++ E T LH + Q +H V+ +QTL+A+ H N IH
Sbjct: 71 -----FRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIH 125
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RD+KP N+L+ + +K+CDFG AR+++ PS
Sbjct: 126 RDVKPENILITKHSVIKLCDFGFARLLT------------------GPSDY--------- 158
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
T+YVATRWYR+PE+++ QY +DVW+ GC+ AELL PL+PGK DQL LI +
Sbjct: 159 -YTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRK 217
Query: 256 TLG--TPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPR 313
TLG P Q++ + + P +FPN S AL LL L DP
Sbjct: 218 TLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEP---LELKFPNISYPALGLLKGCLHMDPT 274
Query: 314 LRITATEALSHPYLVSYHDPDD 335
R+T + L HPY + + +D
Sbjct: 275 ERLTCEQLLHHPYFENIREIED 296
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 176 bits (446), Expect = 5e-44
Identities = 102/322 (31%), Positives = 170/322 (52%), Gaps = 34/322 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+G GA+G+VC A S + VAIKK+ P + RTLREI++L++ H NI+ + D+
Sbjct: 88 IGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTLREIRVLRYINHPNIVPLRDI 147
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIH 135
+ +V+++ +LMQ +LH +I E L E ++ F+ Q LR L+ LH + + H
Sbjct: 148 FRTKGPLGI-DVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHAACIAH 206
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RDLKPSNLL+N + L+I DFG+A+ SS +D +
Sbjct: 207 RDLKPSNLLVNQDGTLRIADFGMAKCADN-------------------SSKKHDDEEHCY 247
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
MT++VAT YRAPE++ ++S ++D+W+ GCI E++ + + PG+ + Q+ ++
Sbjct: 248 YMTQHVATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLT 307
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHPKINW----------RRRFPNASAAALDLLD 305
LG P QE++ V R R+ I+ + W + + +D +
Sbjct: 308 MLGQP-PQEVINEVRCDRTRKLIQDFGRKADAEWDDIMFCKARGDDQIVRGNCDTIDFVK 366
Query: 306 RMLQFDPRLRITATEALSHPYL 327
++ Q+D + RI +AL HPY+
Sbjct: 367 QLFQYDAQKRINIQDALLHPYI 388
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 175 bits (444), Expect = 8e-44
Identities = 119/338 (35%), Positives = 167/338 (49%), Gaps = 41/338 (12%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQ 67
++ + Q +LG+G YGVV A + + VAIKKI ++ +I LREIK+LK +
Sbjct: 8 VADRYLKQEVLGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKELK 67
Query: 68 HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRAL 125
H +II + D +F ++++ E M+TDL VI LS ++ ++ T + L
Sbjct: 68 HPHIILLID-----AFPHKENLHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTFKGL 122
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
H V+HRD+KP+NLL+ + LK+ DFGLARI SP+
Sbjct: 123 AYCHDKWVLHRDMKPNNLLIGVDGQLKLADFGLARIFG------------------SPNR 164
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
T V RWYRAPE++ A QY ++DVW+ CI AELL ++P G
Sbjct: 165 K----------FTHQVFARWYRAPELLFGAKQYGAAVDVWAVACIFAELLLRRPFLQGNS 214
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
DQL IF GTP + +L + EY P + R FP S ALDLL
Sbjct: 215 DIDQLSKIFAAFGTPKADQWPDLTKLPDYVEY----QFVPAPSLRSLFPAVSDDALDLLS 270
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIP 343
+M +DP+ RI+ +AL H Y S P D P P P
Sbjct: 271 KMFTYDPKARISIKQALEHRYFTSAPAPTD-PAKLPKP 307
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 174 bits (442), Expect = 1e-43
Identities = 108/338 (31%), Positives = 172/338 (49%), Gaps = 56/338 (16%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHE 69
SS+F+ LG G Y V +K +G VA+K+++ + +REI ++K +HE
Sbjct: 4 SSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHE 63
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSE-------DHVQYFVYQTL 122
NI+ ++DV N++ ++ E M DL + + ++ + + V+YF +Q L
Sbjct: 64 NIVRLYDV-----IHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLL 118
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
+ L H + ++HRDLKP NLL+N LK+ DFGLAR
Sbjct: 119 QGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAF-------------------- 158
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
G P ++ + V T WYRAP+V++ + YS S+D+WSCGCILAE++ +PLFP
Sbjct: 159 -------GIP-VNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFP 210
Query: 243 GKDYRDQLILIFQTLGTPTEQ---ELVEL------VENRRAREYIRSLPKHPKINWRRRF 293
G + +QL LIF +GTP E + +L ++ R R+ + L H K
Sbjct: 211 GTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTK------- 263
Query: 294 PNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYH 331
+D L +LQ +P +R++A +AL HP+ Y+
Sbjct: 264 EPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYY 301
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 174 bits (442), Expect = 1e-43
Identities = 118/344 (34%), Positives = 186/344 (53%), Gaps = 55/344 (15%)
Query: 16 QSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIF 75
+ ++G G++G+V AK + +GE+VAIKK+ ++ RE++I++ H N +++
Sbjct: 86 EHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKR-----YKNRELQIMQMLDHPNAVAL- 139
Query: 76 DVQKPSSFEQFN--EVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALK 126
K S F + + EVY+ + E + ++RV Q + +V+ + YQ RAL
Sbjct: 140 ---KHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICRALA 196
Query: 127 VLHGS-NVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
+H S + HRD+KP NLL+N + LKICDFG A+++ +
Sbjct: 197 YIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-------------------- 236
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
G+P +S Y+ +R+YRAPE++ A++Y+ ++D+WS GC++AELL QPLFPG+
Sbjct: 237 -----GEPNVS----YICSRYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGE 287
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDL 303
DQL+ I + LGTPT +E+ + N ++ + P HP W + F A+DL
Sbjct: 288 SGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKP-HP---WHKVFQKRLPPEAVDL 343
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
L R Q+ P LR TA EA HP DP+ P G P+P F
Sbjct: 344 LCRFFQYSPNLRCTALEACIHPLFDELRDPNTRLPNGRPLPPLF 387
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 174 bits (441), Expect = 2e-43
Identities = 110/315 (34%), Positives = 162/315 (50%), Gaps = 38/315 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LG+G YG V + SGE++AIKK++ LRE+K LK H N++ + +V
Sbjct: 10 LGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVI 69
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ + + +Y I E M+ +L+++I + E ++ +YQ L+ L +H HR
Sbjct: 70 REN-----DHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHR 124
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL +KI DFGLAR + +
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSK-----------------------------PP 155
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
T+YV+TRWYRAPEV+L + YS +DVW+ GCI+AE+ +PLFPG D + I Q
Sbjct: 156 YTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQV 215
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTP + + E + A + P+ N + PNAS+ A+ LL MLQ+DP+ R
Sbjct: 216 LGTPKKTDWPEGYQLSSAMNF--RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRP 273
Query: 317 TATEALSHPYLVSYH 331
TA++AL +PY H
Sbjct: 274 TASQALRYPYFQVGH 288
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 174 bits (440), Expect = 2e-43
Identities = 119/338 (35%), Positives = 175/338 (51%), Gaps = 49/338 (14%)
Query: 2 GKRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREI 60
GKR V +F + ++GEG YG V A+ K +GE+VA+KK+ EK F I +REI
Sbjct: 720 GKRCV----DKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREI 775
Query: 61 KILKHFQHENIIS----IFDVQKPSSFEQFNEV-YIIQELMQTDLHRVIVTQ--ELSEDH 113
KIL+ H ++++ + D Q F++ Y++ E M DL ++ + SEDH
Sbjct: 776 KILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDH 835
Query: 114 VQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXX 173
++ F+ Q + L+ H N +HRD+K SN+LLN++ +K+ DFGLAR+
Sbjct: 836 IKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARL------------ 883
Query: 174 XXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAE 233
NS S T V T WYR PE++L +Y+ ++DVWSCGCIL E
Sbjct: 884 ------YNSEESRP---------YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 928
Query: 234 LLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRR- 292
L K+P+F QL LI + G+P ++++ Y ++ PK +RRR
Sbjct: 929 LFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIK----LPYFNTM--KPKKQYRRRL 982
Query: 293 ---FPNASAAALDLLDRMLQFDPRLRITATEALSHPYL 327
F +AALDLLD ML DP R TA + L +L
Sbjct: 983 REEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL 1020
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 173 bits (439), Expect = 3e-43
Identities = 108/310 (34%), Positives = 161/310 (51%), Gaps = 38/310 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LG+G YG V K SGE+VAIK+++ LRE+K LK H N+I + +V
Sbjct: 10 LGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVI 69
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ + + +Y I E M+ +L++++ + E ++ +YQ L+ L +H HR
Sbjct: 70 REN-----DHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHR 124
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP NLL +KI DFGLAR + +
Sbjct: 125 DMKPENLLCMGPELVKIADFGLARELRSQ-----------------------------PP 155
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
T+YV+TRWYRAPEV+L ++ YS +DVW+ G I+AEL +PLFPG D++ I Q
Sbjct: 156 YTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQV 215
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTP + + E + + + P+ IN + PNAS A+ L+ ML +DP+ R
Sbjct: 216 LGTPKKSDWPEGYQLASSMNF--RFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRP 273
Query: 317 TATEALSHPY 326
TA++AL HPY
Sbjct: 274 TASQALKHPY 283
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 173 bits (438), Expect = 4e-43
Identities = 115/320 (35%), Positives = 162/320 (49%), Gaps = 42/320 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG YG V AK++ + EIVA+K++ + LREI +LK +H+NI+ + DV
Sbjct: 10 IGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDV 69
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIH 135
++ ++ E DL + +L + V+ F++Q L+ L H NV+H
Sbjct: 70 -----LHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLH 124
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RDLKP NLL+N N +LK+ DFGLAR G P
Sbjct: 125 RDLKPQNLLINRNGELKLADFGLARAF---------------------------GIPVRC 157
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGK-QPLFPGKDYRDQLILIF 254
E V T WYR P+V+ A YS S+D+WS GCI AEL +PLFPG D DQL IF
Sbjct: 158 YSAE-VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIF 216
Query: 255 QTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLDRMLQFDPR 313
+ LGTPTE++ + + + Y P +P + P +A DLL +L+ +P
Sbjct: 217 RLLGTPTEEQWPSMTKLPDYKPY----PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPV 272
Query: 314 LRITATEALSHPYLVSYHDP 333
RI+A EAL HPY + P
Sbjct: 273 QRISAEEALQHPYFSDFCPP 292
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 172 bits (437), Expect = 5e-43
Identities = 116/344 (33%), Positives = 186/344 (53%), Gaps = 49/344 (14%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ + ++G G++GVV AK +GE VAIKK+ + + R L+ +++L H N++
Sbjct: 69 YMAERVVGHGSFGVVFQAKCLETGETVAIKKV--LQDRRYKNRELQTMRLL---DHPNVV 123
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKV 127
S+ ++ + + ++ E + +HRVI + Q + +V+ + YQ RAL
Sbjct: 124 SLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALSY 183
Query: 128 LHGS-NVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+H V HRD+KP NLL+N + +K+CDFG A+++ +
Sbjct: 184 IHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVK--------------------- 222
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+P IS Y+ +R+YRAPE++ A +Y+ ++DVWS GC+LAELL QPLFPG+
Sbjct: 223 ----GEPNIS----YICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGES 274
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRFPNASAAALDL 303
DQL+ I + LGTPT +E+ + N ++ I++ P H KI +R P A+DL
Sbjct: 275 GVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWH-KIFHKRMPPE----AVDL 329
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
+ R+LQ+ P LR A + L HP+ DP+ P G +P F
Sbjct: 330 VSRLLQYSPNLRSAALDTLVHPFFDELRDPNARLPNGRFLPPLF 373
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 172 bits (437), Expect = 5e-43
Identities = 114/344 (33%), Positives = 184/344 (53%), Gaps = 51/344 (14%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ + ++G+G++G+V AK +GE VAIKK+ + + R L+ +++L H N++
Sbjct: 74 YMAERIVGQGSFGIVFQAKCLETGETVAIKKV--LQDKRYKNRELQTMRLL---DHPNVV 128
Query: 73 SI-----FDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKV 127
S+ +K + Y+ + + + H Q + +V+ + YQ RAL
Sbjct: 129 SLKHCFFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAY 188
Query: 128 LHGS-NVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+HG V HRD+KP NLL+N + +K+CDFG A+++ +
Sbjct: 189 IHGGVGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVK--------------------- 227
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+P IS Y+ +R+YRAPE++ A +Y+ ++D+WS GC+LAELL QPLFPG+
Sbjct: 228 ----GEPNIS----YICSRYYRAPELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGES 279
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRFPNASAAALDL 303
DQL+ I + LGTPT +E+ + N ++ I++ P H KI +R P A+DL
Sbjct: 280 GVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWH-KIFHKRTPPE----AVDL 334
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
+ R+LQ+ P LR TA A+ HP+ DP+ P G +P F
Sbjct: 335 VSRLLQYSPNLRSTA--AIVHPFFDELRDPNTRLPNGRALPPLF 376
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 172 bits (437), Expect = 5e-43
Identities = 115/334 (34%), Positives = 170/334 (50%), Gaps = 46/334 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFE-KPLFSIRTLREIKILKHFQHE-N 70
F+ +GEG YG V A+ K +G IVA+KK E + TLREI IL+ + +
Sbjct: 16 FEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLARDPH 75
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-----QELSEDHVQYFVYQTLRAL 125
I+ + DV++ + E +Y++ E + TDL + I + Q + ++ V+ +YQ + +
Sbjct: 76 IVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQNIPQNTVKCLMYQLCKGM 135
Query: 126 KVLHGSNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
HG V+HRDLKP NLL++ LKI D GLAR +
Sbjct: 136 AFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFTL-------------------- 175
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
+ T + T WYRAPEV+L A YS +D+WS GCI AEL+ KQ +F G
Sbjct: 176 --------PMKKYTHEILTLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGD 227
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
QL+ IF+ LGTP E+ + + + EY P+ ++ PN A LDLL
Sbjct: 228 SELQQLLRIFRLLGTPNEEVWPGVSKLKDWHEY----PQWKPLSLSTAVPNLDEAGLDLL 283
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDEPE 338
+ML+++P RI+A +A+ HPY DD P+
Sbjct: 284 SKMLEYEPAKRISAKKAMEHPYF------DDLPD 311
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 172 bits (436), Expect = 7e-43
Identities = 124/363 (34%), Positives = 189/363 (51%), Gaps = 49/363 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ Q ++G G++GVV AK +GE VAIKK+ ++ RE++I++ H N++
Sbjct: 138 YMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKR-----YKNRELQIMRLQDHPNVV 192
Query: 73 ----SIFDV-QKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKV 127
S F K + Y+ + + + H + Q + VQ + YQ RAL
Sbjct: 193 RLRHSFFSTTDKDELYLNLVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQICRALNY 252
Query: 128 LHGS-NVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
LH V HRD+KP NLL+N LKICDFG A+++
Sbjct: 253 LHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVP--------------------- 291
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+P IS Y+ +R+YRAPE++ A +Y+ ++D+WS GC++AELL QPLFPG+
Sbjct: 292 ----GEPNIS----YICSRYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGES 343
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRFPNASAAALDL 303
DQL+ I + LGTPT +E+ + N ++ I++ P H KI +R P A+DL
Sbjct: 344 GIDQLVEIIKILGTPTREEIRCMNPNYTEFKFPQIKAHPWH-KIFHKRMPPE----AVDL 398
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPD-DEPEGTPIPSSFFQFDQWKSRLNTKDLK 362
+ R+LQ+ P LR TA EA +HP+ DP+ P G +P F Q + +T+ +
Sbjct: 399 VSRLLQYSPNLRCTALEACAHPFFDDLRDPNVSLPNGRALPPLFNFTAQELAGASTELRQ 458
Query: 363 RLL 365
RL+
Sbjct: 459 RLI 461
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 172 bits (436), Expect = 7e-43
Identities = 115/344 (33%), Positives = 187/344 (53%), Gaps = 49/344 (14%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ + ++G G++GVV AK +GE VAIKK+ + + R L+ +++L H N++
Sbjct: 73 YMAERVVGHGSFGVVFQAKCLETGETVAIKKV--LQDRRYKNRELQTMRLL---DHPNVV 127
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKV 127
S+ ++ + + ++ E + +HRVI + Q + +V+ + YQ R+L
Sbjct: 128 SLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSY 187
Query: 128 LHGS-NVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+H V HRD+KP NLL+N + +K+CDFG A+++ +
Sbjct: 188 IHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLVK--------------------- 226
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+P IS Y+ +R+YRAPE++ A +Y+ ++DVWS GC+LAELL QPLFPG+
Sbjct: 227 ----GEPNIS----YICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGES 278
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRFPNASAAALDL 303
DQL+ I + LGTPT +E+ + N ++ I++ P H KI +R P A+DL
Sbjct: 279 GVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWH-KIFHKRMPPE----AVDL 333
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
+ R+LQ+ P LR A ++L HP+ DP+ P G +P F
Sbjct: 334 VSRLLQYSPNLRCAALDSLVHPFFDELRDPNARLPNGRFLPPLF 377
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 172 bits (435), Expect = 9e-43
Identities = 120/363 (33%), Positives = 191/363 (52%), Gaps = 55/363 (15%)
Query: 16 QSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIF 75
+ ++G G++G+V AK + +GE+VAIKK+ ++ RE++I++ H N++ +
Sbjct: 85 EHVVGTGSFGMVFQAKCRETGEVVAIKKVLQDKR-----YKNRELQIMQMLDHPNVVCL- 138
Query: 76 DVQKPSSFEQFN--EVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALK 126
K S + + EVY+ + E + ++R + Q + +V+ + YQ R L
Sbjct: 139 ---KHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLA 195
Query: 127 VLHGS-NVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
LH + HRD+KP NLL+N + LKICDFG A+++ +
Sbjct: 196 YLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVK-------------------- 235
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
G+P IS Y+ +R+YRAPE++ A +Y+ ++D+WS GC++AELL QPLFPG+
Sbjct: 236 -----GEPNIS----YICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGE 286
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDL 303
DQL+ I + LGTPT +E+ + N ++ + P HP W + F A+DL
Sbjct: 287 SGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKP-HP---WHKVFQKRLPPEAVDL 342
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSFFQFDQWKSRLNTKDLK 362
L R Q+ P LR TA EA HP+ DP+ P G P+P F Q S + + +
Sbjct: 343 LCRFFQYSPNLRCTAVEACIHPFFDELRDPNARLPNGRPLPPLFNFKPQELSGIPPETVD 402
Query: 363 RLL 365
RL+
Sbjct: 403 RLV 405
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 172 bits (435), Expect = 9e-43
Identities = 117/363 (32%), Positives = 191/363 (52%), Gaps = 50/363 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ + ++G G++G+V AK +GE VAIKK+ + RE+++++ H N+I
Sbjct: 70 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRR-----YKNRELQLMRPMDHPNVI 124
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKV 127
S+ ++ + ++ E + L+RV+ Q + +V+ + YQ R L
Sbjct: 125 SLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLAY 184
Query: 128 LHG-SNVIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+H V HRD+KP NLL++ +K+CDFG A+++ +
Sbjct: 185 IHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVK--------------------- 223
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+P IS Y+ +R+YRAPE++ A +Y+ S+D+WS GC+LAELL QPLFPG++
Sbjct: 224 ----GEPNIS----YICSRYYRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGEN 275
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRFPNASAAALDL 303
DQL+ I + LGTPT +E+ + N + I++ P H K+ +R P A+DL
Sbjct: 276 SVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQIKAHPWH-KVFHKRMPPE----AIDL 330
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSFFQFDQWKSRLNTKDLK 362
R+LQ+ P LR TA EA +HP+ +P+ P G P+P F F Q + + +
Sbjct: 331 ASRLLQYSPSLRCTALEACAHPFFNELREPNARLPNGRPLP-PLFNFKQELGGASMELIN 389
Query: 363 RLL 365
RL+
Sbjct: 390 RLI 392
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 172 bits (435), Expect = 9e-43
Identities = 122/354 (34%), Positives = 174/354 (48%), Gaps = 51/354 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EFQ + + EG YGVV AK K + EIVA+K+++ EK F I +LREI L QH N
Sbjct: 557 EFQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPN 616
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-----QELSEDHVQYFVYQTLRAL 125
I+++ ++ S+ ++ ++I+ + ++ DL ++ T Q V+ Q LRA+
Sbjct: 617 IVTVREIVVGSNMDK---IFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAV 673
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
LH + ++HRDLK SNLLL+ LK+ DFGLAR
Sbjct: 674 AHLHDNWILHRDLKTSNLLLSHKGILKVGDFGLAR------------------------- 708
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G P I T V T WYRAPE++L + YS +DVWS GCI AE L PLFPGK
Sbjct: 709 --EYGSP-IKKYTSLVVTLWYRAPELLLCSPVYSTPIDVWSVGCIFAEFLQMLPLFPGKS 765
Query: 246 YRDQLILIFQTLGTPTEQ---ELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAAL 301
D+L IF+ LGTP E+ EL + ++P R+ F S L
Sbjct: 766 EIDELNRIFKELGTPNEKIWPGYTELPAVKNMLSQNSQFTEYPVSQLRKHFQEKTSEMGL 825
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSR 355
LL +L +DP+ R++A AL H + + P+P F W ++
Sbjct: 826 SLLQGLLTYDPKQRLSADAALKHGFF----------KELPLPIDPSMFPTWPAK 869
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 171 bits (434), Expect = 1e-42
Identities = 109/315 (34%), Positives = 161/315 (50%), Gaps = 38/315 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LG+G YG V + SGE++AIKK++ RE+K LK H N++ + +V
Sbjct: 10 LGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNQREVKSLKKLNHANVVKLKEVI 69
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ + + +Y I E M+ +L+++I + E ++ +YQ L+ L +H HR
Sbjct: 70 REN-----DHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKLGFFHR 124
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL +KI DFGLAR + +
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSK-----------------------------PP 155
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
T+YV+TRWYRAPEV+L + YS +DVW+ GCI+AE+ +PLFPG D + I Q
Sbjct: 156 YTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQV 215
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTP + + E + A + P+ N + PNAS+ A+ LL MLQ+DP+ R
Sbjct: 216 LGTPKKTDWPEGYQLSSAMNF--RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRP 273
Query: 317 TATEALSHPYLVSYH 331
TA++AL +PY H
Sbjct: 274 TASQALRYPYFQVGH 288
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 171 bits (432), Expect = 2e-42
Identities = 118/344 (34%), Positives = 176/344 (50%), Gaps = 50/344 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
+F + ++GEG YG V A+ K +GE+VA+KK+ EK F I +REIKIL+ H++
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763
Query: 71 IIS----IFDVQKPSSFEQFNEV-YIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLR 123
II+ + D + F++ Y++ E M DL ++ + +E+H++ F+ Q +
Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLME 823
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
L H N +HRD+K SN+LLN+ +K+ DFGLAR+ S
Sbjct: 824 GLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYS-------------------- 863
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+ + P T V T WYR PE++L +Y+ ++DVWSCGCIL EL K+P+F
Sbjct: 864 ---SEESRP----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQA 916
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRR----FPNASAA 299
QL LI + G+P ++++ Y ++ PK +RR+ F AA
Sbjct: 917 NQELAQLELISRICGSPCPAVWPDVIK----LPYFNTM--KPKKQYRRKLREEFVFIPAA 970
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIP 343
ALDL D ML DP R TA +AL +L D EP P P
Sbjct: 971 ALDLFDYMLALDPSKRCTAEQALQCEFL-----RDVEPSKMPPP 1009
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 171 bits (432), Expect = 2e-42
Identities = 118/344 (34%), Positives = 176/344 (50%), Gaps = 50/344 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
+F + ++GEG YG V A+ K +GE+VA+KK+ EK F I +REIKIL+ H++
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763
Query: 71 IIS----IFDVQKPSSFEQFNEV-YIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLR 123
II+ + D + F++ Y++ E M DL ++ + +E+H++ F+ Q +
Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLME 823
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
L H N +HRD+K SN+LLN+ +K+ DFGLAR+ S
Sbjct: 824 GLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYS-------------------- 863
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+ + P T V T WYR PE++L +Y+ ++DVWSCGCIL EL K+P+F
Sbjct: 864 ---SEESRP----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQA 916
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRR----FPNASAA 299
QL LI + G+P ++++ Y ++ PK +RR+ F AA
Sbjct: 917 NQELAQLELISRICGSPCPAVWPDVIK----LPYFNTM--KPKKQYRRKLREEFVFIPAA 970
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIP 343
ALDL D ML DP R TA +AL +L D EP P P
Sbjct: 971 ALDLFDYMLALDPSKRCTAEQALQCEFL-----RDVEPSKMPPP 1009
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 171 bits (432), Expect = 2e-42
Identities = 111/320 (34%), Positives = 158/320 (48%), Gaps = 41/320 (12%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
+++ +GEG YGVV A+ K + E +A+KKI E +REI +LK QH N
Sbjct: 3 QYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSN 62
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-VTQELSED--HVQYFVYQTLRALKV 127
I+ DV +Y++ E + DL + + T + S+D ++ ++YQ LR +
Sbjct: 63 IVKYDDVVHSEK-----RLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAY 117
Query: 128 LHGSNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRDLKP NLL++ + LK+ DFGLAR
Sbjct: 118 CHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAF------------------------ 153
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
G P + T V T WYRAPE++L + YS +D+WS GCI AE++ ++PLFPG
Sbjct: 154 ---GIP-VRTFTHEVVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSE 209
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDR 306
DQL IF+ +GTP E + +Y + PK + PN +DLL +
Sbjct: 210 IDQLFKIFRIMGTPYEDTWRGVTS---LPDYKSAFPKWKPTDLETFVPNLDPDGVDLLSK 266
Query: 307 MLQFDPRLRITATEALSHPY 326
ML DP RI A AL H Y
Sbjct: 267 MLLMDPTKRINARAALEHEY 286
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 170 bits (430), Expect = 4e-42
Identities = 116/363 (31%), Positives = 191/363 (51%), Gaps = 50/363 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ + ++G G++G+V AK +GE VAIKK+ + RE+++++ H N++
Sbjct: 72 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRR-----YKNRELQLMRLMDHPNVV 126
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIV-----TQELSEDHVQYFVYQTLRALKV 127
S+ ++ + ++ E + L+RV+ Q + +V+ + YQ R L
Sbjct: 127 SLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAY 186
Query: 128 LHGS-NVIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+H + V HRD+KP NLL++ K+CDFG A+++ +
Sbjct: 187 IHTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLVK--------------------- 225
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+ IS Y+ +R+YRAPE++ A +Y+ S+D+WS GC+LAELL QPLFPG++
Sbjct: 226 ----GEANIS----YICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGEN 277
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRFPNASAAALDL 303
DQL+ I + LGTPT +E+ + N + I++ P H K+ +R P A+DL
Sbjct: 278 SVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQIKAHPWH-KVFHKRMPPE----AIDL 332
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSFFQFDQWKSRLNTKDLK 362
R+LQ+ P LR TA EA +HP+ +P+ P G P+P F F Q S + + +
Sbjct: 333 ASRLLQYSPSLRCTALEACAHPFFNELREPNARLPNGRPLP-PLFNFKQELSGASPELIN 391
Query: 363 RLL 365
RL+
Sbjct: 392 RLI 394
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 169 bits (428), Expect = 6e-42
Identities = 113/323 (34%), Positives = 168/323 (51%), Gaps = 39/323 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG YG V A + +G++VA+K+I EK F I T+RE+KIL+ +H+NI+ + ++
Sbjct: 283 IGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVRLLEI 342
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALKVLHGSNVIH 135
S VY++ E M DL V++ +L + ++++ Q AL LH V+H
Sbjct: 343 MVEKS-----SVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGVLH 397
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RD+K SN+LLN+N DLK DFGLAR N+ S +AN
Sbjct: 398 RDIKGSNILLNNNGDLKFADFGLARF-------------------NTSSKSAN------- 431
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
T V T W+R PE++L Y ++D+WS GCI+ EL +P F G+D QL +I+
Sbjct: 432 -YTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYD 490
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-ASAAALDLLDRMLQFDPRL 314
+GTP E V+N E ++ + + K + F S AA+DL ++L +P
Sbjct: 491 MMGTPDVHSWPE-VKNLPWYELLKPV-EEKKSRFVETFKEILSPAAIDLCQKLLALNPFC 548
Query: 315 RITATEALSHPYLVSYHDPDDEP 337
R +A E L H Y S P EP
Sbjct: 549 RPSAHETLMHEYFTS-ESPPPEP 570
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 169 bits (428), Expect = 6e-42
Identities = 115/339 (33%), Positives = 179/339 (51%), Gaps = 49/339 (14%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
++G G++GVV AK SGE+VAIKK+ + F R E++I++ H NI+ +
Sbjct: 61 VIGNGSFGVVYQAKLCDSGELVAIKKV--LQDKRFKNR---ELQIMRKLDHCNIVRLRYF 115
Query: 78 QKPSSFEQFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKVLHG 130
SS E+ +EVY+ + + + ++RV Q L +V+ ++YQ R+L +H
Sbjct: 116 FY-SSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHS 174
Query: 131 SNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
+ HRD+KP NLLL+ + LK+CDFG A+ +
Sbjct: 175 FGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR------------------------- 209
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
G+P +S Y+ +R+YRAPE++ A Y+ S+DVWS GC+LAELL QP+FPG DQ
Sbjct: 210 GEPNVS----YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ 265
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDRML 308
L+ I + LGTPT +++ E+ N ++ + HP W + F P A+ L R+L
Sbjct: 266 LVEIIKVLGTPTREQIREMNPNYTEFKF-PQIKAHP---WTKVFRPRTPPEAIALCSRLL 321
Query: 309 QFDPRLRITATEALSHPYLVSYHDPD-DEPEGTPIPSSF 346
++ P R+T EA +H + DP+ P G P+ F
Sbjct: 322 EYTPTARLTPLEACAHSFFDELRDPNVKHPNGRDTPALF 360
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 169 bits (427), Expect = 8e-42
Identities = 121/370 (32%), Positives = 177/370 (47%), Gaps = 70/370 (18%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENI 71
F+ +GEG YG V AK +GEIVA+KKI E+ F I +REIKILK HEN+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 72 ISIFDVQ-----------KPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFV 118
I + ++ KP + + +Y++ E M DL + L + ++ ++
Sbjct: 86 IQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYM 145
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXX 178
Q L L H + V+HRD+K SNLL+++ +LK+ DFGLAR S
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHT----------- 194
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
+T V T WYR PE++L A +Y ++D+WS GCI AELL +
Sbjct: 195 ----------------GNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAK 238
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVE-------------NRRAREYIRSLPKHP 285
P+ PGK+ ++QL IF+ G+P E+ + + RR RE+ R +H
Sbjct: 239 PILPGKNEQEQLNKIFELCGSPDEKLWPGVSKMPWFNNFKPARPLKRRVREFFRHFDRH- 297
Query: 286 KINWRRRFPNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
AL+LL++ML DP RI+A +AL Y + P D P+ P S
Sbjct: 298 --------------ALELLEKMLVLDPAQRISAKDALDAEYFWTDPLPCD-PKSLPTYES 342
Query: 346 FFQFDQWKSR 355
+F K R
Sbjct: 343 SHEFQTKKKR 352
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 168 bits (426), Expect = 1e-41
Identities = 119/333 (35%), Positives = 166/333 (49%), Gaps = 37/333 (11%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EF+ + +GEG YG+V A+ + EIVA+KK+ EK I +LREI +L +H N
Sbjct: 38 EFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPN 97
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVL 128
I+ + +V + E ++++ + DL ++ + SE V+ V Q LR L+ L
Sbjct: 98 IVELKEVVVGNHLES---IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 154
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + +IHRDLK SNLL+ +K DFGLAR
Sbjct: 155 HRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAY-------------------------- 188
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + MT V T WYRAPE++L + S+D+W+ GCILAELL +PL PG
Sbjct: 189 -GVP-VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIH 246
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRML 308
Q+ LI Q LGTP+E + +Y SL K P N + +FP S A L LL +
Sbjct: 247 QIDLIVQLLGTPSENIWPGFSKLPLVGQY--SLRKQPYNNLKHKFPWLSEAGLRLLHFLF 304
Query: 309 QFDPRLRITATEALSHPYLVSYHDPDDEPEGTP 341
+DP+ R TA + L Y P EPE P
Sbjct: 305 MYDPKKRATAGDCLESSYFKEKPLP-CEPELMP 336
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 168 bits (425), Expect = 1e-41
Identities = 114/318 (35%), Positives = 161/318 (49%), Gaps = 36/318 (11%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHEN 70
EF+ + +GEG YG+V A+ + EIVA+KK+ EK I +LREI +L +H N
Sbjct: 9 EFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPN 68
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVL 128
I+ + +V + E ++++ + DL ++ + SE V+ V Q LR L+ L
Sbjct: 69 IVELKEVVVGNHLES---IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 125
Query: 129 HGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAN 188
H + +IHRDLK SNLL+ +K DFGLAR
Sbjct: 126 HRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAY-------------------------- 159
Query: 189 DGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRD 248
G P + MT V T WYRAPE++L + S+D+W+ GCILAELL +PL PG
Sbjct: 160 -GVP-VKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIH 217
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRML 308
Q+ LI Q LGTP+E + +Y SL K P N + +FP S A L LL +
Sbjct: 218 QIDLIVQLLGTPSENIWPGFSKLPLVGQY--SLRKQPYNNLKHKFPWLSEAGLRLLHFLF 275
Query: 309 QFDPRLRITATEALSHPY 326
+DP+ R TA + L Y
Sbjct: 276 MYDPKKRATAGDCLESSY 293
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 168 bits (425), Expect = 1e-41
Identities = 108/321 (33%), Positives = 167/321 (51%), Gaps = 43/321 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI--EPFEKPLFSIRTLREIKILKHFQHE 69
+F+ +GEG YGVV +++ +G+IVA+KKI E ++ + S +REI +LK +HE
Sbjct: 3 DFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPST-AIREISLLKELKHE 61
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI----VTQELSEDHVQYFVYQTLRAL 125
NI+ + DV + N +Y+I E + DL + + V + + + V+ ++YQ A+
Sbjct: 62 NIVCLEDV-----LMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAI 116
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
H V+HRDLKP NLL++ + +K+ DFGL R
Sbjct: 117 LFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGR------------------------- 151
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
+ G P + T + T WYRAPEV+L + +YS +D+WS GCI AE+ ++PLF G
Sbjct: 152 --SFGIP-VRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDS 208
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
DQL +F+ L TPTE + +Y + P + N A +DL+
Sbjct: 209 EIDQLFRMFRILKTPTEDIWPGVTS---LPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQ 265
Query: 306 RMLQFDPRLRITATEALSHPY 326
+ML +DP RI+A + L HPY
Sbjct: 266 KMLIYDPVHRISAKDILEHPY 286
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 167 bits (423), Expect = 2e-41
Identities = 114/330 (34%), Positives = 167/330 (50%), Gaps = 52/330 (15%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHE 69
++F +GEG YGVV K++ + +VA+KKI E +REI +LK QH
Sbjct: 20 NDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHP 79
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDH------VQYFVYQTLR 123
N++ + V Q N +++I E + DL R + +L +D ++ + +Q L+
Sbjct: 80 NVVGLEAV-----IMQENRLFLIFEFLSFDLKRYM--DQLGKDEYLPLETLKSYTFQILQ 132
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
A+ H VIHRDLKP NLL+++N +K+ DFGLAR +
Sbjct: 133 AMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAI--------------------- 171
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
G P I T V T WYRAPE+++ A +YS +D+WS GCI AE+ K+PLF G
Sbjct: 172 ------GIP-IRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQG 224
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA----- 298
D+L IF+ LGTPTE E + +Y + PK + R +F +
Sbjct: 225 DSEIDELFRIFRVLGTPTELEWNGV---ESLPDYKATFPKWRENFLRDKFYDKKTGKHLL 281
Query: 299 --AALDLLDRMLQFDPRLRITATEALSHPY 326
A LL+ +L +DP LR+ A +AL HPY
Sbjct: 282 DDTAFSLLEGLLIYDPSLRLNAKKALVHPY 311
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 167 bits (422), Expect = 3e-41
Identities = 110/322 (34%), Positives = 161/322 (49%), Gaps = 55/322 (17%)
Query: 19 LGEGAYGVVCSAKHKPSGE---IVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISI 74
+GEG YGVV A G+ +VA+KKI E +REI +LK + +NI+ +
Sbjct: 14 VGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRL 73
Query: 75 FDVQKPSSFEQFNEVYIIQELMQTDLHRVIV----TQELSEDHVQYFVYQTLRALKVLHG 130
+D+ + +++Y++ E + DL R + Q L D V+ F+ Q + + H
Sbjct: 74 YDIVHSDA----HKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHS 129
Query: 131 SNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDG 190
++HRDLKP NLL+N + +LK+ DFGLAR G
Sbjct: 130 HRILHRDLKPQNLLINKDGNLKLGDFGLARAF---------------------------G 162
Query: 191 DPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQL 250
P + T + T WYRAPEV+L QYS +D WS GCI AE+ ++P+F G DQ+
Sbjct: 163 VP-LRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQI 221
Query: 251 ILIFQTLGTPTEQELVELVENRRAREYIRSL-PKHPKINWRRR-----FPNASAAALDLL 304
IF+ LGTP E ++V Y+ P P+ WRR+ P+ +DLL
Sbjct: 222 FKIFRVLGTPNEAIWPDIV-------YLPDFKPSFPQ--WRRKDLSQVVPSLDPRGIDLL 272
Query: 305 DRMLQFDPRLRITATEALSHPY 326
D++L +DP RI+A A HPY
Sbjct: 273 DKLLAYDPINRISARRAAIHPY 294
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 167 bits (422), Expect = 3e-41
Identities = 100/313 (31%), Positives = 157/313 (49%), Gaps = 37/313 (11%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG Y V K K + +VA+K+I + +RE+ +LK +H NI+++ D+
Sbjct: 171 LGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDI- 229
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ ++ E + DL + + ++ +V+ F++Q LR L H V+HR
Sbjct: 230 ----IHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHR 285
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL+N +LK+ DFGLAR S P+ ++
Sbjct: 286 DLKPQNLLINERGELKLADFGLARAKS------------------IPTKTYSNE------ 321
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
V T WYR P+++L + YS +D+W GCI E+ +PLFPG +QL IF+
Sbjct: 322 ----VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRI 377
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTPTE+ ++ N + Y + PK+ P + DLL ++LQF+ R RI
Sbjct: 378 LGTPTEETWPGILSNEEFKTY--NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRI 435
Query: 317 TATEALSHPYLVS 329
+A +A+ HP+ +S
Sbjct: 436 SAEDAMKHPFFLS 448
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 167 bits (422), Expect = 3e-41
Identities = 100/313 (31%), Positives = 157/313 (49%), Gaps = 37/313 (11%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG Y V K K + +VA+K+I + +RE+ +LK +H NI+++ D+
Sbjct: 123 LGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDI- 181
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ ++ E + DL + + ++ +V+ F++Q LR L H V+HR
Sbjct: 182 ----IHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHR 237
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL+N +LK+ DFGLAR S P+ ++
Sbjct: 238 DLKPQNLLINERGELKLADFGLARAKS------------------IPTKTYSNE------ 273
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
V T WYR P+++L + YS +D+W GCI E+ +PLFPG +QL IF+
Sbjct: 274 ----VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRI 329
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTPTE+ ++ N + Y + PK+ P + DLL ++LQF+ R RI
Sbjct: 330 LGTPTEETWPGILSNEEFKTY--NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRI 387
Query: 317 TATEALSHPYLVS 329
+A +A+ HP+ +S
Sbjct: 388 SAEDAMKHPFFLS 400
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 167 bits (422), Expect = 3e-41
Identities = 112/313 (35%), Positives = 158/313 (49%), Gaps = 42/313 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPL-FSIRTLREIKILKHFQHENIISIFDV 77
+GEG YG V +++ + EIVA+K++ E LREI +LK +H+NI+ + DV
Sbjct: 10 IGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDV 69
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIH 135
++ ++ E DL + + E+ + F+ Q LR L H NV+H
Sbjct: 70 -----LHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLH 124
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RDLKP NLL+N N +LK+ DFGLAR G P
Sbjct: 125 RDLKPQNLLINKNGELKLADFGLARAF---------------------------GIPVKC 157
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRDQLILIF 254
E V T WYR P+V+ A Y+ S+D+WS GCILAEL +PLFPG D DQL+ IF
Sbjct: 158 YSAE-VVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIF 216
Query: 255 QTLGTPTEQELVELVENRRAREYIRSLPKHPKI-NWRRRFPNASAAALDLLDRMLQFDPR 313
+ LGTP E + +Y+ +LP P I +W + P ++ DLL ++L P
Sbjct: 217 RVLGTPNEDSWPGV---SHLSDYV-ALPSFPAITSWSQLVPRLNSKGRDLLQKLLICRPN 272
Query: 314 LRITATEALSHPY 326
RI+A A+ HPY
Sbjct: 273 QRISAEAAMQHPY 285
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 166 bits (421), Expect = 4e-41
Identities = 109/318 (34%), Positives = 156/318 (48%), Gaps = 40/318 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG YG V A++K SGEIVA+K++ + LREI IL+ +H N++ ++DV
Sbjct: 10 IGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYDV 69
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIH 135
N++ ++ E DL + + + + + Q LR L H +V+H
Sbjct: 70 VHSE-----NKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLH 124
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RDLKP NLL+N+N LK+ DFGLAR G P
Sbjct: 125 RDLKPQNLLINTNGTLKLADFGLARAF---------------------------GVPVRC 157
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGK-QPLFPGKDYRDQLILIF 254
E V T WYR P+V+ A Y+ S+D+WS GCI AE+ +PLFPG D DQL IF
Sbjct: 158 FSAE-VVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIF 216
Query: 255 QTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRL 314
+ LG+P+E + + +Y HP + W + PN ++ DLL ++L +P
Sbjct: 217 KQLGSPSEDNWPSITQ---LPDYKPYPIYHPTLTWSQIVPNLNSRGRDLLQKLLVCNPAG 273
Query: 315 RITATEALSHPYLVSYHD 332
RI A AL H Y D
Sbjct: 274 RIDADAALRHAYFADTSD 291
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 166 bits (421), Expect = 4e-41
Identities = 108/332 (32%), Positives = 174/332 (51%), Gaps = 46/332 (13%)
Query: 17 SLLGEGAYGVVCSAKHKPSGEIVAIKK-IEPFEKPLFSIRTLREIKILKHFQHENIISIF 75
S LGEG+YGVV K++ +G+IVAIKK +E + P LREI++LK +H+N++ +
Sbjct: 8 SKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNLVGLI 67
Query: 76 DVQKPSSFEQFNEVYIIQELM-QTDLHRVIVTQE-LSEDHVQYFVYQTLRALKVLHGSNV 133
+V F++ +++++ EL +T LH + ++++ ++ +YQ L ALK H
Sbjct: 68 EV-----FKRNRKLHLVFELCDRTVLHELEKNPHGVNDELIKKIIYQLLEALKFCHSHKC 122
Query: 134 IHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPA 193
IHRD+KP N+ L N +K+ DFG ARI++
Sbjct: 123 IHRDVKPENIFLTRNDQVKLGDFGFARIIN-----------------------------T 153
Query: 194 ISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILI 253
T+YVATRWYR+PE+++ QY +D+W+ GC+ AELL + L+PG+ DQL I
Sbjct: 154 TEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHI 213
Query: 254 FQTLGTPTEQELVELVENRRAREYIRSL----PKHPKINWRRRFPNASAAALDLLDRMLQ 309
+TLG + L + R ++ L P+H + + PNAS+A LD L + +
Sbjct: 214 RKTLG----EFLPRHISIFRTNQFFFGLSIPEPEHLE-PLPSKLPNASSAQLDFLQKCFE 268
Query: 310 FDPRLRITATEALSHPYLVSYHDPDDEPEGTP 341
P R + +E + H ++ + E TP
Sbjct: 269 MSPDRRFSCSELMLHGIFSNWILRIRQDESTP 300
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 166 bits (421), Expect = 4e-41
Identities = 111/324 (34%), Positives = 169/324 (51%), Gaps = 40/324 (12%)
Query: 5 IVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILK 64
+VF + +++ LG+G G V A + + E+VA+KK++ LRE+K L+
Sbjct: 5 VVF-VMCRYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALR 63
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTL 122
H +II + ++ + + NE++ I E M +L+ ++ +E SE ++ F+ Q L
Sbjct: 64 KLNHPHIIKLKEIVR-----EHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQML 118
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
+ L +H + HRDLKP NLL+ +N LKI DFGLAR V+
Sbjct: 119 QGLAHMHKNGYFHRDLKPENLLVTNNI-LKIADFGLAREVA------------------- 158
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
++ TEYV+TRWYRAPEV+L ++ Y+ ++D+W+ G ILAEL PLFP
Sbjct: 159 ----------SMPPYTEYVSTRWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTPLFP 208
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
G+ DQL I LG P E R S + P+ PNA+ A+D
Sbjct: 209 GESEIDQLYKICCVLGKPDWTTFPEAKSISRIMSI--SHTEFPQTRIADLLPNAAPEAID 266
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
L++R+ +DP R TA EAL+HP+
Sbjct: 267 LINRLCSWDPLKRPTADEALNHPF 290
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 166 bits (420), Expect = 5e-41
Identities = 112/342 (32%), Positives = 166/342 (47%), Gaps = 46/342 (13%)
Query: 5 IVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFE-KPLFSIRTLREIKIL 63
I + F+ +GEG YG V A+ K +G+IVA+KK E + TLREI IL
Sbjct: 6 IAVSAMDAFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISIL 65
Query: 64 KHFQHE-NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-----QELSEDHVQYF 117
+ + +++ + DV++ S E +Y++ E M TD+ + I + + + ++
Sbjct: 66 RMLARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKNIPTQTIKSL 125
Query: 118 VYQTLRALKVLHGSNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXX 176
+YQ + + HG ++HRDLKP NLL++ LKI D GLAR +
Sbjct: 126 MYQLCKGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFTL------------ 173
Query: 177 XXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLG 236
+ T + T WYRAPEV+L A YS ++D+WS GCI AEL+
Sbjct: 174 ----------------PMKKYTHEILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVT 217
Query: 237 KQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA 296
Q +F G QL+ IF+ GTP E+ + + EY P+ PN
Sbjct: 218 NQAIFQGDSELQQLLHIFKLFGTPNEEMWPGVSTLKNWHEY----PQWKPSTLSSAVPNL 273
Query: 297 SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPE 338
A +DLL +MLQ++P RI+A A+ HPY DD PE
Sbjct: 274 DEAGVDLLSKMLQYEPAKRISAKMAMEHPYF------DDLPE 309
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 166 bits (420), Expect = 5e-41
Identities = 110/321 (34%), Positives = 164/321 (50%), Gaps = 36/321 (11%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHE 69
SEF+ + +GEG+YG+V A+ S EIVA+KK+ EK I LREI ILK HE
Sbjct: 51 SEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHE 110
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKV 127
NI+ + +V S + ++++ + + DL V+ ++Q +E V+ Q L+ALK
Sbjct: 111 NIVRLREVVVGKSLDS---IFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKY 167
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
LH +IHRDLK SNLL+ +K+ DFGLAR+ S N P
Sbjct: 168 LHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFS-----------------NPPKP-- 208
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYR 247
MT + T WYRAPE++L ++ ++D+W+ GCIL ELL +PL PG
Sbjct: 209 ---------MTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEI 259
Query: 248 DQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRM 307
QL +I LG P+E + + + +L + P N +F + +LL+ +
Sbjct: 260 AQLDMIIDLLGAPSESIWPGFADLPAVQNF--TLSQQPYNNLTPKFHMIGQSGRNLLNIL 317
Query: 308 LQFDPRLRITATEALSHPYLV 328
++P+ R TA E L Y V
Sbjct: 318 FIYNPKTRATAEECLKSKYFV 338
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 165 bits (418), Expect = 9e-41
Identities = 110/353 (31%), Positives = 178/353 (50%), Gaps = 28/353 (7%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPF-EKPLFSIRTLREIKILKHFQHE 69
+++ L LGEG +G V ++ + G++ A+K+I EK F I +REIKILK +HE
Sbjct: 34 TDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHE 93
Query: 70 NIISIFD---VQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRA 124
NII + D V+ + +Y++ M DL ++ + +E ++ ++ Q
Sbjct: 94 NIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAG 153
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
K LH ++HRDLK +NLL++++ LKI DFGLAR+++E
Sbjct: 154 TKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANK-------------- 199
Query: 185 SAANDGDPAISGM--TEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
N G P + T V TRWYR+PE++L +Y+ ++D+WS GCI+AE+ +P+
Sbjct: 200 ---NPGLPPPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQ 256
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
G DQL IF+ G+PT+ + E E +RS P HP+ F
Sbjct: 257 GSSDLDQLDKIFRLCGSPTQATMPNW-EKLPGCEGVRSFPSHPR-TLETAFFTFGKEMTS 314
Query: 303 LLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSR 355
L +L +P R++A+ AL H Y + P + P S+ ++D+ + R
Sbjct: 315 LCGAILTLNPDERLSASMALEHEYFTTPPYPAN-PSELQSYSASHEYDKRRKR 366
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 165 bits (418), Expect = 9e-41
Identities = 117/357 (32%), Positives = 173/357 (47%), Gaps = 44/357 (12%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENI 71
F+ +GEG YG V AK +GEIVA+KKI E+ F I +REIKILK HEN+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 72 ISIFDVQ-----------KPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFV 118
I + ++ KP + + +Y++ E M DL + L + ++ ++
Sbjct: 86 IHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYM 145
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXX 178
Q L L H + V+HRD+K SNLL+++ +LK+ DFGLAR S
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHT----------- 194
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQ 238
+T V T WYR PE++L A +Y ++D+WS GCI AELL +
Sbjct: 195 ----------------GNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGK 238
Query: 239 PLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASA 298
P+ PGK +QL I++ G+P E + + + S P ++ R + +
Sbjct: 239 PILPGKTENEQLNKIYELCGSPDESNWPGVSKMPWYNQMKSSRPLKRRV--REIYRHFDR 296
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSR 355
AL+LL++ML DP RI A +AL Y + P D P+ P S +F K R
Sbjct: 297 HALELLEKMLVLDPSQRICAKDALDAEYFWTDPLPCD-PKSLPTYESSHEFQTKKKR 352
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 164 bits (416), Expect = 1e-40
Identities = 108/343 (31%), Positives = 175/343 (50%), Gaps = 47/343 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
+ + ++G G++G+V AK +GE VAIKK+ + RE+++++ H N++
Sbjct: 40 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRR-----YKNRELQLMRVMDHPNVV 94
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKV 127
+ ++ + + ++ E + L+RV+ Q + +V+ ++YQ R L
Sbjct: 95 CLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAY 154
Query: 128 LHG-SNVIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+H + V HRDLKP NLL++ +KICDFG A+ + +
Sbjct: 155 IHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVK--------------------- 193
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
G+ IS Y+ +R+YRAPE++ A +Y+ S+D+WS GC+LAELL QPLFPG++
Sbjct: 194 ----GEANIS----YICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGEN 245
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLL 304
DQL+ I + LGTPT +E + + + HP W + F A+D
Sbjct: 246 AVDQLVEIIKVLGTPTREE-IRCMNPHYTDFRFPQIKAHP---WHKIFHKRMPPEAIDFA 301
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
R+LQ+ P LR TA EA +HP+ +P+ P G P P F
Sbjct: 302 SRLLQYSPSLRCTALEACAHPFFDELREPNARLPNGRPFPPLF 344
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 164 bits (415), Expect = 2e-40
Identities = 103/330 (31%), Positives = 169/330 (51%), Gaps = 37/330 (11%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFE-KPLFSIRTLREIKILKHFQ 67
++ E+ + +GEG Y VV +G +AIK+I+ E K + +RE+K L+ Q
Sbjct: 3 VNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQ 62
Query: 68 HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRAL 125
H N+I + D+ F ++ + ++ E + TDL VI + + + ++ ++ TLR +
Sbjct: 63 HPNVIELIDI-----FMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGV 117
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
H + ++HRDLKP+NLL + + +K+ DFGLAR + +P
Sbjct: 118 YHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIP------------------APHE 159
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
+T V TRWYRAPE++ A Y+ ++D+WS G I AEL+ + P PG++
Sbjct: 160 I----------LTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQN 209
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
DQ+ + F+ LGTPT+++ E V + ++ P + R+RF AS ALD +
Sbjct: 210 DVDQMEVTFRALGTPTDRDWPE-VSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMC 268
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDD 335
ML +P+ R TA + L Y P D
Sbjct: 269 GMLTMNPQKRWTAVQCLESDYFKELPPPSD 298
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 164 bits (415), Expect = 2e-40
Identities = 109/318 (34%), Positives = 163/318 (50%), Gaps = 39/318 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFE-KPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG Y VV + K + VAIKKI+ + K I LREIK L+ +H+N+I + DV
Sbjct: 17 VGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNVIELVDV 76
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALKVLHGSNVIH 135
F + + II E + +DL +I + + H++ ++ LR L +H ++H
Sbjct: 77 -----FSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFILH 131
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RDLKP+NLL++S+ LK+ DFGL+R + G P S
Sbjct: 132 RDLKPNNLLISSDGVLKLADFGLSR---------------------------DFGTP--S 162
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
M+ V TRWYR PE+ + Y +D+WS GCI AEL+ + P PG+ DQL +IF+
Sbjct: 163 HMSHQVITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFR 222
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLR 315
LGTP E E+++ ++ ++ +P P F A +DLL ML ++P R
Sbjct: 223 ALGTP-EPEVIKSMQQLPNYVEMKHIPP-PNGGMEALFSAAGHEEIDLLKMMLDYNPYRR 280
Query: 316 ITATEALSHPYLVSYHDP 333
TA +AL H Y + P
Sbjct: 281 PTAQQALEHHYFSALPKP 298
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 164 bits (415), Expect = 2e-40
Identities = 102/315 (32%), Positives = 163/315 (51%), Gaps = 46/315 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIR--TLREIKILKHFQHENIISIFD 76
+GEG+YG V KHK +G+IVAIK +E+P S+ +REIK LK F HEN++++ +
Sbjct: 10 VGEGSYGTVMKCKHKNTGQIVAIKIF--YERPEQSVNKIAMREIKFLKQFHHENLVNLIE 67
Query: 77 VQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE-----LSEDHVQYFVYQTLRALKVLHGS 131
V F Q +++++ E + H V+ + L ++ +++Q LRA+ LH +
Sbjct: 68 V-----FRQKKKIHLVFEFID---HTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN 119
Query: 132 NVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGD 191
N+IHRD+KP N+L++ + K+CDFG AR + A GD
Sbjct: 120 NIIHRDIKPENILVSQSGITKLCDFGFAR------------------------TLAAPGD 155
Query: 192 PAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLI 251
T+YVATRWYRAPE++L Y K +D+W+ GC++ E+ P P D L
Sbjct: 156 I----YTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLH 211
Query: 252 LIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFD 311
I +G + ++ + +HPK N R+++P + D++ LQ D
Sbjct: 212 KIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPK-NARKKYPKLNGLLADIVHACLQID 270
Query: 312 PRLRITATEALSHPY 326
P RI++++ L H Y
Sbjct: 271 PADRISSSDLLHHEY 285
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 164 bits (415), Expect = 2e-40
Identities = 106/310 (34%), Positives = 155/310 (49%), Gaps = 38/310 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LG+G YG V + K +GE VAIK+++ LRE+K LK H NI+ + +V
Sbjct: 10 LGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKLKEVI 69
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ + + +Y + E M+ +L+++I ++ L E ++ ++Q L L +H HR
Sbjct: 70 REN-----DTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHR 124
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL + +KI DFGLAR + R
Sbjct: 125 DLKPENLLCSGPDLIKIADFGLAREIRSR-----------------------------PP 155
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
T+YV+TRWYRAPEV+L + Y ++D+W+ GCI+AEL +PLFPG DQL I
Sbjct: 156 FTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSV 215
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTP + + + R A P K+ S LDLL+ ML +DP R
Sbjct: 216 LGTPDKDDWPD--GYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRP 273
Query: 317 TATEALSHPY 326
TA ++L +PY
Sbjct: 274 TAQQSLKYPY 283
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 164 bits (414), Expect = 3e-40
Identities = 106/334 (31%), Positives = 176/334 (51%), Gaps = 42/334 (12%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
++G G++GVV S AIK++ + F R L+ ++I+KH ++I+ +
Sbjct: 37 VVGSGSFGVVMQVHLIESDSKAAIKRV--LQDKRFKNRELQIMRIMKHPNIVDLIAYYYT 94
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHR---VIVTQELSED--HVQYFVYQTLRALKVLHGSN 132
+S E + + ++ E M ++R + Q+LS V+ ++YQ LR+L +H S
Sbjct: 95 TGDNSDEVY--LNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHASG 152
Query: 133 VIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGD 191
+ HRD+KP NLLL+ N LK+CDFG A+I+ G+
Sbjct: 153 ICHRDIKPQNLLLDPENGILKLCDFGSAKILVA-------------------------GE 187
Query: 192 PAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLI 251
P +S Y+ +R+YRAPE++ A Y+ ++D+WS GC++AEL+ PLFPG+ DQL+
Sbjct: 188 PNVS----YICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLV 243
Query: 252 LIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFD 311
I + LGTP+ +++ + N + + P+ + R P ALDLL +MLQ+
Sbjct: 244 EIIKILGTPSREQIKTMNPNYMEHRFPQIRPQPLSRVFSRSVP---LDALDLLSKMLQYT 300
Query: 312 PRLRITATEALSHPYLVSYHDPDDEPEGTPIPSS 345
P R+TA EA+ HP+ DP+ + + P +
Sbjct: 301 PTDRLTAAEAMCHPFFDELRDPNTKLHNSRNPDA 334
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 164 bits (414), Expect = 3e-40
Identities = 114/350 (32%), Positives = 183/350 (51%), Gaps = 61/350 (17%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
++ + ++G G++GVV AK + E VAIKK+ ++ RE++I++ H N++
Sbjct: 102 YRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKR-----YKNRELQIMRMLDHPNVV 156
Query: 73 SIFDVQKPSSFE--QFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLR 123
+ K S F + +E+Y+ + E + ++R + Q + ++Q + YQ R
Sbjct: 157 EL----KHSFFSTTEKDELYLNLVLEYVPETIYRASRSYTKMNQHMPLIYIQLYTYQICR 212
Query: 124 ALKVLHGS-NVIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
A+ LH V HRD+KP NLL+N+ ++KICDFG A+++
Sbjct: 213 AMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSAKMLIP----------------- 255
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
G+P IS Y+ +R+YRAPE++ A +Y+ ++D+WS GC++AEL PLF
Sbjct: 256 --------GEPNIS----YICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLF 303
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKIN---WRRRF-PNAS 297
PG+ DQL+ I + LGTP +E+ + N R ++ K P+I W + F S
Sbjct: 304 PGETSVDQLVEIIKILGTPAREEIKNM--NPRYNDF-----KFPQIKAQPWHKIFRRQVS 356
Query: 298 AAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
A+DL R+LQ+ P LR TA EA +HP+ DP P G +P F
Sbjct: 357 PEAMDLASRLLQYSPNLRCTALEACAHPFFDDLRDPRASLPNGRALPPLF 406
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 163 bits (413), Expect = 3e-40
Identities = 103/327 (31%), Positives = 167/327 (50%), Gaps = 55/327 (16%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKK-IEPFEKPLFSIRTLREIKILKHFQHEN 70
+++ L+GEG+YG+V ++K +G IVAIKK +E + + +REIK+LK +HEN
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQY-----FVYQTLRAL 125
++++ +V K Y++ E + H ++ EL + + Y +++Q + +
Sbjct: 63 LVNLLEVCKKKK-----RWYLVFEFVD---HTILDDLELFPNGLDYQVVQKYLFQIINGI 114
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
H N+IHRD+KP N+L++ + +K+CDFG AR ++ +P
Sbjct: 115 GFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLA------------------APGE 156
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
T+YVATRWYRAPE+++ +Y K++DVW+ GC++ E+ +PLFPG
Sbjct: 157 V----------YTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDS 206
Query: 246 YRDQLILIFQTLGT--PTEQELVELVENRRAREYIRSLPKHPKINWR----RRFPNASAA 299
DQL I LG P QEL + + + + P+I R RR+P S
Sbjct: 207 DIDQLYHIMMCLGNLIPRHQELFN-------KNPVFAGVRLPEIKEREPLERRYPKLSEV 259
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPY 326
+DL + L DP R E L H +
Sbjct: 260 VIDLAKKCLHIDPDKRPFCAELLHHDF 286
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 163 bits (413), Expect = 3e-40
Identities = 107/324 (33%), Positives = 159/324 (49%), Gaps = 43/324 (13%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQ 67
++ FQ +GEG YGVV A+ + + +VA+KKI E T+REI +LK+ +
Sbjct: 1 MTESFQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLK 60
Query: 68 HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE-----LSEDHVQYFVYQTL 122
H I+ + DV N++Y++ E ++ DL R + + E V+ Q L
Sbjct: 61 HSTIVELSDV-----IYNNNKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLL 115
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
A++ H N+ HRDLKP N+L++ ++K+ DFGL R
Sbjct: 116 TAMEYCHSRNIFHRDLKPQNILVDPKENIKLADFGLGRAA-------------------- 155
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
G P + TE V T WYR PE++L Y S+DVWS CI+AE++ +P FP
Sbjct: 156 -------GIPLRTYTTE-VVTLWYRPPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFP 207
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
G DQL IF+ LGTP VEN Y P ++ + F +D
Sbjct: 208 GDSEIDQLFRIFKVLGTPNNSRWSN-VEN--FPNYKVEFPVWDPVDLKTIF-RGDPDFVD 263
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
L+ +ML++DP++R+TA LSH Y
Sbjct: 264 LISKMLEYDPKMRMTAKNGLSHKY 287
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 163 bits (413), Expect = 3e-40
Identities = 106/321 (33%), Positives = 163/321 (50%), Gaps = 41/321 (12%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQ 67
I FQ +GEG YG+V A+ +G+ VA+KKI E +REI +LK+ +
Sbjct: 4 ILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLK 63
Query: 68 HENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRAL 125
H N++ +FDV N +Y+I E + DL +++ ++ + ++ +++Q L A+
Sbjct: 64 HPNVVQLFDVVISG-----NNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAV 118
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
H + ++HRDLKP NLL+++ +K+ DFGLAR N P
Sbjct: 119 GFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLAR------------------AFNVPMR 160
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
A T V T WYRAPE++L YS +D+WS GCI +E++ ++ LFPG
Sbjct: 161 A----------YTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDS 210
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
DQL IF+TL TP E + + ++ P+ N + P A +L+
Sbjct: 211 EIDQLYRIFRTLSTPDETNWPGVTQ---LPDFKTKFPRWEGTNMPQ--PITEHEAHELIM 265
Query: 306 RMLQFDPRLRITATEALSHPY 326
ML +DP LRI+A +AL H Y
Sbjct: 266 SMLCYDPNLRISAKDALQHAY 286
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 162 bits (410), Expect = 7e-40
Identities = 108/339 (31%), Positives = 179/339 (51%), Gaps = 49/339 (14%)
Query: 16 QSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIF 75
Q ++G G++GVV AK + E+VAIKK+ + F R E++I++ H NI+ +
Sbjct: 39 QKVIGNGSFGVVFLAKLSTTNEMVAIKKV--LQDKRFKNR---ELQIMRKLNHPNIVKL- 92
Query: 76 DVQKPSSFEQFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKVL 128
SS E+ +E+Y+ I E + ++RV Q++ +V+ ++YQ LR+L +
Sbjct: 93 KYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYI 152
Query: 129 HGSNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
H + HRD+KP NLL++ LK+CDFG A+ +
Sbjct: 153 HSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRN---------------------- 190
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYR 247
+P +S Y+ +R+YRAPE++ A Y+ S+DVWS G ++AELL QP+FPG
Sbjct: 191 ---EPNVS----YICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGV 243
Query: 248 DQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-PNASAAALDLLDR 306
DQL+ I + LGTPT +++ + N + ++ + HP W + F + A A+DL+ +
Sbjct: 244 DQLVEIIKVLGTPTREQIQSMNPNYKEFKF-PQIKAHP---WNKVFRVHTPAEAIDLISK 299
Query: 307 MLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPS 344
++++ P R T A H + +PD P G P+P+
Sbjct: 300 IIEYTPTSRPTPQAACQHAFFDELRNPDARLPSGRPLPT 338
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 162 bits (409), Expect = 1e-39
Identities = 114/348 (32%), Positives = 180/348 (50%), Gaps = 54/348 (15%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
++G G++GVV AK SGE+VAIKK+ + F R E++I++ H NI+ +
Sbjct: 61 VIGNGSFGVVYQAKLCDSGELVAIKKV--LQDKRFKNR---ELQIMRKLDHCNIVRLRYF 115
Query: 78 QKPSSFEQFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKVLHG 130
SS E+ +EVY+ + + + ++RV Q L +V+ ++YQ R+L +H
Sbjct: 116 FY-SSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHS 174
Query: 131 SNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
+ HRD+KP NLLL+ + LK+CDFG A+ +
Sbjct: 175 FGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVR------------------------- 209
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
G+P +S Y+ +R+YRAPE++ A Y+ S+DVWS GC+LAELL QP+FPG DQ
Sbjct: 210 GEPNVS----YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ 265
Query: 250 LILIFQTLGTPTEQELVELVENRRAREY--IRSLPKHPKINWRRRF--------PNASAA 299
L+ I + LGTPT +++ E+ N ++ I++ P + F P
Sbjct: 266 LVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPE 325
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
A+ L R+L++ P R+T EA +H + DP+ + P G P+ F
Sbjct: 326 AIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF 373
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 161 bits (407), Expect = 2e-39
Identities = 100/290 (34%), Positives = 154/290 (52%), Gaps = 48/290 (16%)
Query: 94 ELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKI 153
ELM +L +VI EL + + Y +YQ L +K LH + +IHRDLKPSN+++ S+C LKI
Sbjct: 2 ELMDANLCQVI-QMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKI 60
Query: 154 CDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVML 213
DFGLAR MT YV TR+YRAPEV+L
Sbjct: 61 LDFGLARTAGTSFM-----------------------------MTPYVVTRYYRAPEVIL 91
Query: 214 TAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRR 273
Y +++D+WS GCI+ E++ + LFPG+DY DQ + + LGTP + + +L
Sbjct: 92 GMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL--QPT 148
Query: 274 AREYIRSLPKHPKINWRRRFPNA------------SAAALDLLDRMLQFDPRLRITATEA 321
R Y+ + PK+ + + + FP++ ++ A DLL +ML DP RI+ +A
Sbjct: 149 VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDA 208
Query: 322 LSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKRLLWNEIVS 371
L HPY+ ++DP E E P Q D+ + + ++ K L++ E+++
Sbjct: 209 LQHPYINVWYDP-AEVEAPPPQIYDKQLDEREHTI--EEWKELIYKEVMN 255
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 160 bits (405), Expect = 3e-39
Identities = 95/313 (30%), Positives = 153/313 (48%), Gaps = 37/313 (11%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG Y V + K + +VA+K+I + +RE+ +LK +H NI+++ D+
Sbjct: 198 LGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIV 257
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ ++ E + DL + + +S +V+ F+YQ LR L H V+HR
Sbjct: 258 HTDK-----SLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHR 312
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL+N +LK+ DFGLAR S
Sbjct: 313 DLKPQNLLINEKGELKLADFGLARAKSVPTKTY--------------------------- 345
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
+ V T WYR P+V+L +++Y +D+W GCI E+ +PLFPG D+L LIF+
Sbjct: 346 -SNEVVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRL 404
Query: 257 LGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRI 316
LGTP+++ + N + Y + PK+ P + ++L+ + LQ++ + R+
Sbjct: 405 LGTPSQETWPGISSNEEFKNY--NFPKYKPEPLINHAPRLDSEGIELIRKFLQYESKKRV 462
Query: 317 TATEALSHPYLVS 329
+A EA+ H Y S
Sbjct: 463 SAEEAMKHVYFRS 475
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 160 bits (405), Expect = 3e-39
Identities = 110/333 (33%), Positives = 164/333 (49%), Gaps = 37/333 (11%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENI 71
F++ + +GEG YG V A+ + ++VA+KK+ EK F I +REIKIL+ H NI
Sbjct: 804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNI 863
Query: 72 ISIFDV--QKPSSFE---QFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLRA 124
+++ ++ K + E Y++ E M DL ++ + + +E++ + Q L
Sbjct: 864 VNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDG 923
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
L H N +HRD+K SN+L+N+ +K+ DFGLAR+ +
Sbjct: 924 LNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYN--------------------- 962
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
D T V T WYR PE++L +Y S+DVWSCGCIL EL K+PLF
Sbjct: 963 -----ADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQAN 1017
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
QL I + G+P ++ + + K + R F A ALDLL
Sbjct: 1018 AEMAQLETISKICGSPVPAVWPNVI--KLPLFHTLKQKKTHRRRLREDFEFMPAPALDLL 1075
Query: 305 DRMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
D+ML DP RITA +AL P+L +PD+ P
Sbjct: 1076 DKMLDLDPDKRITAEDALRSPWLRKI-NPDEMP 1107
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 159 bits (403), Expect = 5e-39
Identities = 110/348 (31%), Positives = 175/348 (49%), Gaps = 60/348 (17%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEI--------VAIKKIEPFEKPLFSIR---TLREIK 61
+ L +G+G +G V A +K + E+ VAIK+++ K FS LRE+K
Sbjct: 4 YTLLKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMK---KKYFSWEECVNLREVK 60
Query: 62 ILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVY 119
L H NI+ + +V + + +Y + E M+ +L++++ + +E ++ + +
Sbjct: 61 SLSRMNHPNIVKLKEVIRENDI-----LYFVFEYMECNLYQLMKDRPKHFAESDIRNWCF 115
Query: 120 QTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXX 179
Q + L +H HRDLKP NLL++ + +KI D GLAR +
Sbjct: 116 QVFQGLSYMHQRGYFHRDLKPENLLVSKDV-IKIADLGLAREI----------------- 157
Query: 180 XNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
D P TEYV+TRWYRAPEV+L + Y+ +D+W+ G I+AELL +P
Sbjct: 158 ---------DSSPPY---TEYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRP 205
Query: 240 LFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAA 299
LFPG D++ I +G+PTE+ +E + Y P+ P ++ P ASA
Sbjct: 206 LFPGASEADEIYKICSVIGSPTEETWLEGLNLASVINY--QFPQFPGVHLSSVMPYASAD 263
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVS-YHDPD------DEPEGT 340
A++L++R+ +DP R T EAL HP+ S Y+ P EP G+
Sbjct: 264 AVNLIERLCSWDPCNRPTTAEALQHPFFQSCYYIPPSLRPKLSEPRGS 311
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 159 bits (401), Expect = 8e-39
Identities = 113/347 (32%), Positives = 171/347 (48%), Gaps = 52/347 (14%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHE 69
+ + + +GEG YG V A + +GE VA+K++ EK F I +REIKIL+ H+
Sbjct: 309 THYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHK 368
Query: 70 NIISIFDVQKPS-SFEQFNEV----YIIQELMQTDLHRVIVTQEL---SEDHVQYFVYQT 121
NI+ + D+ S ++ Y++ E + DL ++ ++EL ++D + Q
Sbjct: 369 NIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQL 428
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
L L +H + +HRD+K SN+L+N+ +LKI D GLAR+ +
Sbjct: 429 LEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRL------------- 475
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
T V T WYR PE++L +Y ++DVWS GC+L EL ++PLF
Sbjct: 476 ---------------YTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLF 520
Query: 242 PGKDYRDQLILIFQTLGTPTEQ---ELVELV---ENRRAREYIRSLPKHPKINWRRRFPN 295
G + QL LI + G+P EL ELV R R Y R + R F +
Sbjct: 521 NGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRI--------REEFEH 572
Query: 296 -ASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTP 341
A+DLLD+ML +P RI+A EAL+HP++ S +P P
Sbjct: 573 IMPREAVDLLDKMLTLNPEKRISAKEALNHPWIRSLEHTTVQPLKLP 619
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 159 bits (401), Expect = 8e-39
Identities = 110/330 (33%), Positives = 160/330 (48%), Gaps = 53/330 (16%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQH--------- 68
+GEG YG V A K +G++VA+KK ++ LREI +L+
Sbjct: 10 VGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSIYIVRLLC 69
Query: 69 -ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE-------LSEDHVQYFVYQ 120
E++I D S + +Y++ E + TDL + I + L VQ F++Q
Sbjct: 70 VEHVIQSKD--STVSHSPKSNLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASLVQRFMFQ 127
Query: 121 TLRALKVLHGSNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXX 179
+ + H V+HRDLKP NLLL+ + LKI D GL+R +
Sbjct: 128 LFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTV--------------- 172
Query: 180 XNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
+ T + T WYRAPEV+L + YS ++D+WS GCI AE++ +Q
Sbjct: 173 -------------PLKAYTHEIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQA 219
Query: 240 LFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAA 299
LFPG QL+ IF+ LGTPTEQ+ ++ R Y PK + R P+ S
Sbjct: 220 LFPGDSEFQQLLHIFRLLGTPTEQQWPGVMALRDWHVY----PKWEPQDLSRAVPSLSPE 275
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVS 329
+DLL +ML+++P RI+A AL HPY S
Sbjct: 276 GIDLLTQMLKYNPAERISAKAALDHPYFDS 305
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 157 bits (397), Expect = 2e-38
Identities = 106/340 (31%), Positives = 178/340 (52%), Gaps = 50/340 (14%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
++G G++GVV AK +GE+VAIKK+ + F R E++I++ +H NI+ +
Sbjct: 553 VIGNGSFGVVFQAKLCDTGELVAIKKV--LQDRRFKNR---ELQIMRKLEHCNIVKLLYF 607
Query: 78 QKPSSFEQFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKVLHG 130
SS E+ +EV++ + E + +++V Q + + ++ ++YQ R+L +H
Sbjct: 608 FY-SSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHS 666
Query: 131 SNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
+ HRD+KP NLLL+ LK+CDFG A+ +
Sbjct: 667 LGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLH------------------------- 701
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
G+P +S Y+ +R+YRAPE++ A Y+ +DVWS GC+LAELL QP+FPG DQ
Sbjct: 702 GEPNVS----YICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQ 757
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFP-NASAAALDLLDRML 308
L+ + + LGTPT +++ E+ N ++ + HP W++ F A++L+ +L
Sbjct: 758 LVEVIKVLGTPTREQIREMNPNYTEFKF-PQIKSHP---WQKVFRIRTPTEAINLVSLLL 813
Query: 309 QFDPRLRITATEALSHPYLVSYHDPDDE--PEGTPIPSSF 346
++ P RIT +A +HP+ + P G +P F
Sbjct: 814 EYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLF 853
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 156 bits (394), Expect = 5e-38
Identities = 98/310 (31%), Positives = 156/310 (49%), Gaps = 45/310 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEP---FEKPLFSIRTLREIKILKHFQHENIISIF 75
+ G++G V + K + A+K++ P ++ FSI +RE+ ILKH +H NI+ I
Sbjct: 32 ISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMILKHIRHRNIMEIE 91
Query: 76 DVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ-ELSEDHVQYFVYQTLRALKVLHGSNVI 134
+V + + N+ +I+ E TDL VI + ++ ++ Q L+ LK LHG+ ++
Sbjct: 92 EVVEGC---EINDFFIVMECCDTDLRSVIHSVGKIGMKAARFLTCQMLKGLKFLHGAGIV 148
Query: 135 HRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAI 194
HRDLKPSN+LL + L+I DFGLAR +
Sbjct: 149 HRDLKPSNILLMRDGGLRIADFGLARAIE------------------------------- 177
Query: 195 SGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIF 254
S MT V T WYR E++L + Y +S+D+WS GC++ E+L +P+ G+ DQL IF
Sbjct: 178 SQMTNLVVTLWYRPIEILLGSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIF 237
Query: 255 QTLGTPTEQEL--VELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDP 312
+ LG PT+ + ++L + R P + ++ F A + +L FDP
Sbjct: 238 RLLGYPTDADFEGLDLPHFKNIRR-----PSTFEASFEGDFECYGEEAASFVRNLLSFDP 292
Query: 313 RLRITATEAL 322
R R TA++ L
Sbjct: 293 RKRCTASQGL 302
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 155 bits (393), Expect = 7e-38
Identities = 112/346 (32%), Positives = 163/346 (46%), Gaps = 49/346 (14%)
Query: 3 KRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKI 62
K + F +S + LGEG+Y V + +G++VA+K I + +RE +
Sbjct: 42 KSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASL 101
Query: 63 LKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQ 120
LK +H NI+ + D+ F + E M TDL + + L +V+ F++Q
Sbjct: 102 LKGLKHANIVLLHDIIHTKETLTF-----VFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQ 156
Query: 121 TLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXX 180
LR L +H +V+HRDLKP NLL++ +LK+ DFGLAR S
Sbjct: 157 LLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKS----------------- 199
Query: 181 NSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPL 240
PS + V T WYR P+ +L A +YS +D+W GCI E+ QPL
Sbjct: 200 -IPSQT----------YSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPL 248
Query: 241 FPG-KDYRDQLILIFQTLGTPTEQEL--VELVENRRAREYIRSLPKHPKINWRR--RFPN 295
FPG + +QL I++ LG PTE V + N + P+ + W R R P
Sbjct: 249 FPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPE 308
Query: 296 ASAAALDLLDRMLQFDPRLRITATEALSHPYLVS-----YHDPDDE 336
A DL +ML+ PR R++A EAL H Y + Y PD+E
Sbjct: 309 AE----DLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEE 350
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 154 bits (390), Expect = 2e-37
Identities = 102/327 (31%), Positives = 164/327 (49%), Gaps = 47/327 (14%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKK-IEPFEKPLFSIRTLREIKILKHFQHENI 71
++ S LGEG+YGVV + + +G +VA+K+ +E + P LREI++LK+ +H N+
Sbjct: 4 YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNL 63
Query: 72 ISIFDVQKPSSFEQFNEVYIIQELMQ-TDLHRVIVTQELSEDHV-QYFVYQTLRALKVLH 129
+S+ +V F + ++++ E + T LH + + +H+ + YQTL + H
Sbjct: 64 VSLLEV-----FRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCH 118
Query: 130 GSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
+HRD+KP N+LL + +K+CDFG AR++S
Sbjct: 119 KQGCLHRDIKPENILLTAQGQVKLCDFGFARMLSPG------------------------ 154
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
T+YVATRWYRAPE+++ QY +DVW+ GC+ AEL+ + L+PG+ DQ
Sbjct: 155 -----ENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSDVDQ 209
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIR--SLPKHPKIN-WRRRFPNAS---AAALDL 303
L LI +TLG + + +N EY + +LP P + + P S +D
Sbjct: 210 LYLIRKTLGDLLPRHIQIFGQN----EYFKGITLPVPPTLEPLEDKMPAKSQQNPLTIDF 265
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSY 330
L + L DP R + + H Y Y
Sbjct: 266 LKKCLDKDPTKRWSCEKLTKHSYFDDY 292
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 154 bits (388), Expect = 3e-37
Identities = 108/343 (31%), Positives = 165/343 (47%), Gaps = 51/343 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPF-EKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG YGVV A H A+K I ++ LREI +K QH+NI+++FD+
Sbjct: 51 IGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDI 110
Query: 78 QKPSSFEQFNEV-----------YIIQELMQTDLHRVIVTQE-----LSEDHVQYFVYQT 121
S F +N + Y++ E + DL ++ E L ++V+ F++Q
Sbjct: 111 IYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMWQL 170
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
L AL H ++HRDLKP N+L++ + +KI DFGLAR S
Sbjct: 171 LSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFS------------------ 212
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
PS T V T WYR PE++L + +YS S+D+WS GCI +E+ +PLF
Sbjct: 213 FPSR----------NYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLF 262
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA--SAA 299
PG+ QL IF+ +GTP + + Y P+ P +N ++ + +
Sbjct: 263 PGECEISQLFKIFEIVGTPNIKSWPGV---DSFPHYKAVFPQWP-VNLKKLEETSCLTGN 318
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPI 342
LD+L +L++ P R+TA ALSH Y + + P T +
Sbjct: 319 GLDVLREILRYPPERRLTAKGALSHRYFLQNGFTQNRPSVTDL 361
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 153 bits (387), Expect = 3e-37
Identities = 90/272 (33%), Positives = 146/272 (53%), Gaps = 39/272 (14%)
Query: 57 LREIKILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHV 114
LRE+K L+ H NI+ + +V + + +Y + E M+ +L++++ ++ +E +
Sbjct: 14 LREVKSLRRMNHPNIVKLKEVIRENDI-----LYFVFEYMECNLYQLMKDRQKLFAEADI 68
Query: 115 QYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXX 174
+ + +Q + L +H HRDLKP NLL++ + +KI DFGLAR V+
Sbjct: 69 KNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKDI-IKIADFGLAREVN----------- 116
Query: 175 XXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAEL 234
+SP TEYV+TRWYRAPEV+L + Y+ +D+W+ G I+AEL
Sbjct: 117 ------SSPP------------FTEYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAEL 158
Query: 235 LGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFP 294
L +P+FPG D++ I +GTPTE+ +E + Y P+ P + P
Sbjct: 159 LSLRPIFPGASEADEIYKICSVIGTPTEETWLEGLNLANTINY--QFPQLPGVPLSSLMP 216
Query: 295 NASAAALDLLDRMLQFDPRLRITATEALSHPY 326
+AS A++L++R+ +DP R TA E L HP+
Sbjct: 217 SASEDAINLIERLCSWDPSSRPTAAEVLQHPF 248
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 153 bits (386), Expect = 4e-37
Identities = 103/323 (31%), Positives = 162/323 (49%), Gaps = 43/323 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKH-KPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKH---F 66
+++ + +GEGAYG V A+ K G VA+K++ + + T+RE+ +L+H F
Sbjct: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETF 71
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRV---IVTQELSEDHVQYFVYQTLR 123
+H N++ +FDV S ++ ++ ++ E + DL + + + ++ ++Q LR
Sbjct: 72 EHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLR 131
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
L LH V+HRDLKP N+L+ S+ +K+ DFGLARI S +
Sbjct: 132 GLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQ------------------ 173
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+T V T WYRAPEV+L ++ Y+ +D+WS GCI AE+ ++PLF G
Sbjct: 174 -----------MALTSVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRG 221
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
DQL I +G P E++ V R + +S K + DL
Sbjct: 222 SSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKF-----VTDIDELGKDL 276
Query: 304 LDRMLQFDPRLRITATEALSHPY 326
L + L F+P RI+A ALSHPY
Sbjct: 277 LLKCLTFNPAKRISAYSALSHPY 299
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 153 bits (386), Expect = 4e-37
Identities = 114/342 (33%), Positives = 173/342 (50%), Gaps = 39/342 (11%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIK-ILKHFQH 68
SE+ + +++ EG YG V K+ + E+VA+K+ + EK F I LREI +LK H
Sbjct: 397 SEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAH 456
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIV-----TQELSEDHVQYFVYQTLR 123
ENI+++ ++ S+ EVY+ E ++ D+ +I Q + + Q L
Sbjct: 457 ENIVNVKEILVGSTK---TEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLS 513
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
++ +H ++HRDLK SNLL++ + LKI DFGLAR E
Sbjct: 514 GIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGE------------------- 554
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
A D + + +T V T WYR+PE++L YS +D+WS GCI+AE + +P+F G
Sbjct: 555 ---ARDIEKRMK-LTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQG 610
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN---ASAAA 300
+Q+ IFQ +GTPTEQ ++ E + + P P RR F +
Sbjct: 611 DSEPNQVHQIFQMMGTPTEQIWPDIKE-LKVWNMVEFPPVKPG-QLRRIFKGEKLVNETG 668
Query: 301 LDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPI 342
DLL+ ML +P R+TA+EAL H + S H PE P+
Sbjct: 669 FDLLNGMLCLNPANRLTASEALQHDWF-SEHPKAVPPEDLPV 709
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 153 bits (386), Expect = 4e-37
Identities = 107/326 (32%), Positives = 159/326 (47%), Gaps = 47/326 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHE----NIIS 73
+GEG YG V A K +G++VA+KK ++ LREI +L+ ++
Sbjct: 10 VGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSTSIYVVRLLC 69
Query: 74 IFDVQKPSSFEQFNE--VYIIQELMQTDLHRVIVT-------QELSEDHVQYFVYQTLRA 124
+ V +PS+ Q + +Y++ E + TDL + I + + L +Q ++Q +
Sbjct: 70 VEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKLMFQLCKG 129
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDL-KICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
+ H V+HRDLKP NLLL + +L KI D GL R +
Sbjct: 130 VAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTV------------------- 170
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+ T + T WYRAPEV+L + YS +D+WS GCI AE++ +Q LFPG
Sbjct: 171 ---------PLKSYTHEIVTLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPG 221
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
QL+ IF+ LGTPTEQ+ + R Y PK + P+ S +DL
Sbjct: 222 DSEFQQLLHIFRLLGTPTEQQWPGVSTLRDWHVY----PKWEPQDLTLAVPSLSPQGVDL 277
Query: 304 LDRMLQFDPRLRITATEALSHPYLVS 329
L +ML+++P RI+A AL HPY S
Sbjct: 278 LTKMLKYNPAERISAKTALDHPYFDS 303
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 152 bits (384), Expect = 8e-37
Identities = 106/320 (33%), Positives = 153/320 (47%), Gaps = 32/320 (10%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHENIISIF-- 75
LG+G +G V H + VA+KKI EK LF I REI ILK H+NII +
Sbjct: 66 LGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEM 125
Query: 76 ------DVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSED--HVQYFVYQTLRALKV 127
D+ +S Y+I M DL V+ ++ + ++ + Q L L
Sbjct: 126 VYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNY 185
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
+H + +HRD+K +N+L++ N LK+ DFGLAR+ P+
Sbjct: 186 IHCAKFMHRDIKTANILIDHNGVLKLADFGLARLY----------------YGCPPNLKY 229
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYR 247
G + + T V TRWYRAPE++L QY+ ++D+W GC+ AE K+P+ GK
Sbjct: 230 PGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDI 289
Query: 248 DQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-ASAAALDLLDR 306
DQ +IF+ LGTPTE++ R + K R RF S LD L +
Sbjct: 290 DQGHVIFKLLGTPTEEDWAV----ARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQ 345
Query: 307 MLQFDPRLRITATEALSHPY 326
+L DP R+TA A HP+
Sbjct: 346 LLALDPYKRLTAMSAKHHPW 365
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 152 bits (384), Expect = 8e-37
Identities = 101/332 (30%), Positives = 164/332 (48%), Gaps = 56/332 (16%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEG YG V AK+ + ++VA+KK+ E+ F I ++REIK+L+ F H N+ +I ++
Sbjct: 189 VGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEI 248
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQ--YFVYQTLRALKVLHGSNVIH 135
S VY+I E DL +++ +E+ H Q + Q L ++ LH + ++H
Sbjct: 249 MVESQ----KTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILH 304
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RD+K SN+L+++ +LKI DFGLAR ++ R +
Sbjct: 305 RDVKGSNILIDNQGNLKITDFGLARKMNSR-----------------------------A 335
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
T V T WYR PE++L Y +D+W CGC+L EL K +F G + +Q+ IF+
Sbjct: 336 DYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFK 395
Query: 256 TLGTPT--------EQELVELVENRRAREYIRSLPKHPKINWRRRFPNA--SAAALDLLD 305
+GTPT + ++ ++ +Y+ N+ +F + S+ L L
Sbjct: 396 IMGTPTINSWPTLYDMPWFFMIMPQQTTKYVN--------NFSEKFKSVLPSSKCLQLAI 447
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
+L +D R +ATEAL Y +P EP
Sbjct: 448 NLLCYDQTKRFSATEALQSDYF--KEEPKPEP 477
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 152 bits (384), Expect = 8e-37
Identities = 101/327 (30%), Positives = 157/327 (47%), Gaps = 43/327 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG Y V + K + +VA+K+I + +RE+ +LK+ +H NI+++ D+
Sbjct: 148 LGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDL- 206
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ ++ E + +DL + + +S +V+ F++Q LR L H ++HR
Sbjct: 207 ----IHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHR 262
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLL+N +LK+ DFGLAR S
Sbjct: 263 DLKPQNLLINERGELKLADFGLARAKSVPTKT---------------------------- 294
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
+ V T WYR P+V+L + +YS +D+W GCI E+ +PLFPG +++L LIF+
Sbjct: 295 YSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRL 354
Query: 257 LGTPTEQELVELVENRRAREYIRSLP---KHPKINWRRRFPNASAAALDLLDRMLQFDPR 313
LGTPTE+ + R Y S P P IN P + LL +L ++ +
Sbjct: 355 LGTPTEETWPGVTAFSEFRTY--SFPCYLPQPLIN---HAPRLDTDGIHLLSSLLLYESK 409
Query: 314 LRITATEALSHPYLVSYHDPDDEPEGT 340
R++A ALSH Y S + + E T
Sbjct: 410 SRMSAEAALSHSYFRSLGERVHQLEDT 436
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 151 bits (382), Expect = 1e-36
Identities = 96/314 (30%), Positives = 154/314 (48%), Gaps = 46/314 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LG+G +G V AK +G+ VAIK+++ +LRE+K LK H NII + +V
Sbjct: 51 LGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNHPNIIKLREVI 110
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIHR 136
+ + +Y + E MQ +L+ ++ ++ E ++ +YQ L+ L +H + HR
Sbjct: 111 RENDI-----LYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHR 165
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP N++ N +KI DFGLAR + +
Sbjct: 166 DMKPENIMCNGTELVKIADFGLAREIRSK-----------------------------PP 196
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQT 256
T+YV+TRWYRAPE++L + Y+ +D+W+ GCI+AEL +PLFPG DQL I
Sbjct: 197 YTDYVSTRWYRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISI 256
Query: 257 LGTPTEQELVELVENRRAREY----IRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDP 312
LGTP + E E + A + + + P +N S + L+ M+ ++P
Sbjct: 257 LGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVN------TISKEGMKLMMDMMLWNP 310
Query: 313 RLRITATEALSHPY 326
R A ++L + Y
Sbjct: 311 EKRPNANQSLRYKY 324
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 151 bits (381), Expect = 2e-36
Identities = 103/325 (31%), Positives = 158/325 (47%), Gaps = 40/325 (12%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF 66
F + ++ LGEG+Y V K K +G++VA+K I E+ +RE +LK
Sbjct: 111 FGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGL 170
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRA 124
+H NI+ + D+ + ++ E + TDL + + L D+V+ F++Q LR
Sbjct: 171 KHANIVLLHDI-----IHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRG 225
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
L +H ++HRDLKP NLL++ +LK+ DFGLAR S PS
Sbjct: 226 LSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKS------------------VPS 267
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG- 243
+ V T WYR P+V+L + +YS +D+W GCI E++ FPG
Sbjct: 268 HT----------YSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGM 317
Query: 244 KDYRDQLILIFQTLGTPTEQEL--VELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
KD +DQL IF LGTP E V + + + + K+ + W + + A
Sbjct: 318 KDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKL--SYVNHAE 375
Query: 302 DLLDRMLQFDPRLRITATEALSHPY 326
DL ++LQ P+ R++A ALSH Y
Sbjct: 376 DLASKLLQCSPKNRLSAQAALSHEY 400
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 151 bits (381), Expect = 2e-36
Identities = 103/323 (31%), Positives = 166/323 (50%), Gaps = 42/323 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPL-FSIRTLREIKILKHFQ--- 67
+FQ+ LG+GAYG V + G+ A+K+I K LREI ++KH
Sbjct: 37 DFQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKA 96
Query: 68 HENIISIFDV-QKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRA 124
H NIIS+ V + ++ +I E DLH + + + + E ++ Q +RA
Sbjct: 97 HPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRA 156
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
L LH ++IHRDLKP N+LLN + +K+ DFGL++ S
Sbjct: 157 LDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNT------------------- 197
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
+ T V T WYR+PEV+L + Y+ ++D+W+ GCI++E+ +QPLF G+
Sbjct: 198 ----------TAFTTLVVTLWYRSPEVLLQS-YYNSTVDMWALGCIVSEIYCRQPLFVGQ 246
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLL 304
+ +QL IF+ +GTP ++ E+ AR+ S P++ N + P S A++ +
Sbjct: 247 NEAEQLTDIFKKMGTPVGKDWPS--ESVIARD---SFPQYRPTNLKDLSPQMSKQAIEFV 301
Query: 305 DRMLQFDPRLRITATEALSHPYL 327
+ L++D R++A ALSHP+L
Sbjct: 302 QQCLRYDHSKRLSARGALSHPFL 324
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 151 bits (381), Expect = 2e-36
Identities = 112/356 (31%), Positives = 174/356 (48%), Gaps = 51/356 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIK-ILKHFQHE 69
E++ + + EG +GVV K K + EIVA+K+++ EK F I LREI +LK H
Sbjct: 355 EYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHP 414
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT-----QELSEDHVQYFVYQTLRA 124
NI+++ ++ S+ ++ +Y+ E ++ D+ ++ T + S + + Q L
Sbjct: 415 NIVNVKEILLGSNMDK---IYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSG 471
Query: 125 LKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPS 184
++ +H ++HRDLK SNLL++ LKI DFGLAR
Sbjct: 472 IEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAR------------------------ 507
Query: 185 SAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
GDP + T V T WYR+PE++L YS +D+WS GCI+AE + +PLFPG+
Sbjct: 508 ---EYGDP-LKKFTSIVVTLWYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGR 563
Query: 245 DYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA---SAAAL 301
+Q+ IF +GTPTE + E + + K+P R+RF +
Sbjct: 564 GELEQIKKIFMEMGTPTESIWPGVTELDGWKAL--TFEKYPYNQLRKRFLAGRLLNDTGF 621
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLN 357
LL+ +L DP+ R +AT+AL H + E P+P F KS N
Sbjct: 622 KLLNGLLTLDPKNRFSATQALDHEWFTE--------EPYPVPPEEFPTFPAKSEQN 669
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 151 bits (381), Expect = 2e-36
Identities = 104/321 (32%), Positives = 159/321 (49%), Gaps = 42/321 (13%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIE-PFEKPLFSIRTLREIKILKHFQ---H 68
+Q +++GEGAYG V A+ +G IVA+KK+ + + TLREI +LK H
Sbjct: 26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNH 85
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI---VTQELSEDHVQYFVYQTLRAL 125
NI+ +++V + + + ++ E ++ DL +I +S +Q + L +
Sbjct: 86 ANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGV 145
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
LH +IHRDLKP NLL++S LKI DFGLA+
Sbjct: 146 DFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMK------------------ 187
Query: 186 AANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKD 245
+T V T WYRAPEV+L A Y+ ++D+WS CI+ E+ ++ LFPG
Sbjct: 188 -----------LTSVVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTS 235
Query: 246 YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
++QL IF+ G PTEQ+ + + + + + PK PK P+ A DLL+
Sbjct: 236 EKNQLDRIFELTGRPTEQQWPQTI-SVALEHFPQRHPKRPK----DFCPHLCKYADDLLN 290
Query: 306 RMLQFDPRLRITATEALSHPY 326
+ML +D LR +A L H Y
Sbjct: 291 KMLSYDLHLRPSALACLEHDY 311
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 150 bits (380), Expect = 2e-36
Identities = 108/342 (31%), Positives = 176/342 (50%), Gaps = 60/342 (17%)
Query: 4 RIVFNISSEFQLQSLLGEGAYGVVCSAKHK-PSGEIVAIKKIEPFEKPLFSIRTLREI-K 61
R +I + + +G+G +G V A K PS E+VAIK ++ + LRE+
Sbjct: 27 RKCISIDEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHS 86
Query: 62 ILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE---LSEDHVQYFV 118
+L+ ++ENI++IFD+ +QF ++I+ E + +L+++I T++ L+ + VQ +
Sbjct: 87 LLRLSENENIVNIFDLY----IDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIM 142
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSNCD-----LKICDFGLARIVSERXXXXXXXX 173
Q + L +H + HRD+KP N+L++SN D +KI DFGLAR ++ R
Sbjct: 143 RQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSR-------- 194
Query: 174 XXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAE 233
TEYV+TRWYRAPE++L + YS +D+++ GC+ E
Sbjct: 195 ---------------------PPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFE 233
Query: 234 LLGKQPLFPGKDYRDQLILIFQTLGTPTEQ------------ELVELVENRRAREYIRSL 281
+ QP+FPG D DQL + + LG+P EQ + EL+ N+ SL
Sbjct: 234 IATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIWDRAELLANKLG----ISL 289
Query: 282 PKHPKINWRRRF-PNASAAALDLLDRMLQFDPRLRITATEAL 322
PK +++ F P + A +L ++L++DP R TA L
Sbjct: 290 PKMAPLDFGDLFSPPWNLAFASMLSQLLKWDPAKRPTAEMCL 331
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 150 bits (380), Expect = 2e-36
Identities = 104/334 (31%), Positives = 172/334 (51%), Gaps = 36/334 (10%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKI-EPFEKPLFSIRTLREIKILKHFQHE 69
S+++ + +G+G +G V A+H+ +G+ VA+KK+ EK F I LREIKIL+ +HE
Sbjct: 17 SKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE 76
Query: 70 NIISIFDV--QKPSSFEQFN-EVYIIQELMQTDL----HRVIVTQELSEDHVQYFVYQTL 122
N++++ ++ K S + + +Y++ + + DL V+V LSE ++ + L
Sbjct: 77 NVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSE--IKRVMQMLL 134
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
L +H + ++HRD+K +N+L+ + LK+ DFGLAR S
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS------------------- 175
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
A + P + T V T WYR PE++L Y +D+W GCI+AE+ + P+
Sbjct: 176 ---LAKNSQP--NRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQ 230
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLP-KHPKINWRRRFPNASAAAL 301
G + QL LI Q G+ T E+ V+N E + + + K+ R + AL
Sbjct: 231 GNTEQHQLALISQLCGSIT-PEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYAL 289
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDD 335
DL+D++L DP RI + +AL+H + S P D
Sbjct: 290 DLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSD 323
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 150 bits (379), Expect = 3e-36
Identities = 105/350 (30%), Positives = 171/350 (48%), Gaps = 45/350 (12%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQH 68
+ F ++G G++GVV + + + E VAIKK+ + F R E++I+K H
Sbjct: 35 VQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKV--LQDKRFKNR---ELEIMKMLSH 89
Query: 69 ENIISI--FDVQKPSSFEQFNEV---YIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLR 123
NII + F ++ S E + + Y+ Q L Q H V +S ++Y+++Q +
Sbjct: 90 INIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFK 149
Query: 124 ALKVLHG-SNVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
+L LH +NV HRD+KP NLL++ LK+CDFG A+ +
Sbjct: 150 SLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPT---------------- 193
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
+P +S Y+ +R+YRAPE++ A Y+ +D+WS GC++AELL QP+F
Sbjct: 194 ---------EPNVS----YICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMF 240
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
PG+ DQL+ I + LGTP++QE+ + N ++ P+ I R F +
Sbjct: 241 PGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKF----PQIKPIPLSRVFKKEDDQTV 296
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQ 351
+ L +L++DP R A + L PY D + +FD+
Sbjct: 297 EFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKINQITTDLKLLEFDE 346
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 150 bits (378), Expect = 4e-36
Identities = 103/324 (31%), Positives = 159/324 (48%), Gaps = 48/324 (14%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG+Y V + K G IVA+K+I+ + +RE +L++ +H NI+S+ D+
Sbjct: 114 LGEGSYATVYKCESKLDGSIVALKEIKLQFQEGLPFTAIREASLLRNLRHANIVSLHDI- 172
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHV--QYFVYQTLRALKVLHGSNVIHR 136
F Q +++ + E M+ DL + + D + + ++Q LR L H ++HR
Sbjct: 173 ----FYQHHQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLFQLLRGLDFCHRKKILHR 228
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
DLKP NLLL+ + LK+ DFGLAR S PS
Sbjct: 229 DLKPQNLLLDEDGVLKLADFGLARAKS------------------VPSRT---------- 260
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG-KD-----YRDQL 250
+ V T WYR P+V++ + YS S+D+W GCI AE+ LFPG KD +DQL
Sbjct: 261 YSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQL 320
Query: 251 ILIFQTLGTPTEQELVELVENRRAREYIRSL-PKHPKINW---RRRFPNASAAALDLLDR 306
+IF GTP E++ E+ + Y L P++ ++++ F +LL
Sbjct: 321 DMIFSIRGTPDEKKWPEV---KTLPGYTPELFPRYRELSFIAVNPMFTKILKTGQELLGM 377
Query: 307 MLQFDPRLRITATEALSHPYLVSY 330
+LQ P R++A A+ HPY S+
Sbjct: 378 LLQLRPESRVSAASAMLHPYFASF 401
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 150 bits (378), Expect = 4e-36
Identities = 114/344 (33%), Positives = 177/344 (51%), Gaps = 64/344 (18%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHK-PSGEIVAIKKIEPFEK-PLFSIRTLREIKILKHFQHE 69
++ L +GEG YG+V A+ K P +AIKK + + S +REI +L+ HE
Sbjct: 24 QYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREISHE 83
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVI------VTQELSEDHVQYFVYQTLR 123
N++ + +V +F + +Y+ + + DL+ +I V L+ V+ ++Q L
Sbjct: 84 NVVKLVNVH--INFADMS-LYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSLLWQLLN 140
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCD----LKICDFGLARIVSERXXXXXXXXXXXXXX 179
L LH + +IHRDLKPSN+L+ + + +KI DFGLARI
Sbjct: 141 GLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADFGLARIYQ---------------- 184
Query: 180 XNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
+P +D V T WYRAPE++L + Y+ ++D+W+ GCI AELL +P
Sbjct: 185 --APLKPLSDNG--------VVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKP 234
Query: 240 LFPGKDYR--------DQLILIFQTLGTPTEQE---LVEL------VENRRAREYIRSLP 282
LF G + + DQL IF+ LG PT + LV L V++ +A +Y S+
Sbjct: 235 LFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKY-DSVG 293
Query: 283 KHPKINWRRRFPNASAAALDLLDRMLQFDPRLRITATEALSHPY 326
H ++ ++ P A DLL +ML++DP RITA++AL H Y
Sbjct: 294 LHNVVHLNQKSP-----AYDLLSKMLEYDPLKRITASQALEHEY 332
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 148 bits (374), Expect = 1e-35
Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 35/310 (11%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG Y V + + + VA+K+I ++ +RE+ +L++ +H N++++ D+
Sbjct: 367 LGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDII 426
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSNVIHRDL 138
Y+ ++L Q + + ++++ F+YQ LR L H V+HRDL
Sbjct: 427 HTDRLLTLVFEYVDRDLKQ---YMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDL 483
Query: 139 KPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMT 198
KP NLL+ + +LK+ DFGLAR S +
Sbjct: 484 KPQNLLITAKGELKLADFGLARAKSVPTKTY----------------------------S 515
Query: 199 EYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLG 258
V T WYR P+V+L + YS +D+W GCIL E++ + LFPG +QL LIF+TLG
Sbjct: 516 NEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLG 575
Query: 259 TPTEQELVELVENRRAREYI-RSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRIT 317
+P + E Y R P R+ P A +LL + LQ++ + R++
Sbjct: 576 SPRPDRHPTICEKPTFYPYANRHYNPDPLC---RQIPRIDAHGFELLMKFLQYEGKDRVS 632
Query: 318 ATEALSHPYL 327
A EA+ HP+L
Sbjct: 633 AAEAVKHPFL 642
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 148 bits (374), Expect = 1e-35
Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 35/310 (11%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG Y V + + + VA+K+I ++ +RE+ +L++ +H N++++ D+
Sbjct: 244 LGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDII 303
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSNVIHRDL 138
Y+ ++L Q + + ++++ F+YQ LR L H V+HRDL
Sbjct: 304 HTDRLLTLVFEYVDRDLKQ---YMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDL 360
Query: 139 KPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMT 198
KP NLL+ + +LK+ DFGLAR S +
Sbjct: 361 KPQNLLITAKGELKLADFGLARAKSVPTKTY----------------------------S 392
Query: 199 EYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLG 258
V T WYR P+V+L + YS +D+W GCIL E++ + LFPG +QL LIF+TLG
Sbjct: 393 NEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLG 452
Query: 259 TPTEQELVELVENRRAREYI-RSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRIT 317
+P + E Y R P R+ P A +LL + LQ++ + R++
Sbjct: 453 SPRPDRHPTICEKPTFYPYANRHYNPDPLC---RQIPRIDAHGFELLMKFLQYEGKDRVS 509
Query: 318 ATEALSHPYL 327
A EA+ HP+L
Sbjct: 510 AAEAVKHPFL 519
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 148 bits (373), Expect = 1e-35
Identities = 104/339 (30%), Positives = 159/339 (46%), Gaps = 48/339 (14%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEK-------PLFSIRTLREIKI 62
+S ++ + +G GAYG V A+ SG VA+K + P+ ++R + ++
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 63 LKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE---LSEDHVQYFVY 119
L+ F+H N++ + DV S ++ +V ++ E + DL + L + ++ +
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 120 QTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXX 179
Q LR L LH + ++HRDLKP N+L+ S +K+ DFGLARI S +
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQ-------------- 168
Query: 180 XNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
+T V T WYRAPEV+L + Y+ +D+WS GCI AE+ ++P
Sbjct: 169 ---------------MALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKP 212
Query: 240 LFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAA 299
LF G DQL IF +G P E + V R + P + P +
Sbjct: 213 LFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRG-----AFPPRGPRPVQSVVPEMEES 267
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPE 338
LL ML F+P RI+A AL H YL H + PE
Sbjct: 268 GAQLLLEMLTFNPHKRISAFRALQHSYL---HKDEGNPE 303
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 148 bits (373), Expect = 1e-35
Identities = 106/340 (31%), Positives = 162/340 (47%), Gaps = 62/340 (18%)
Query: 19 LGEGAYGVV-------------CSAKHKPSGEIVAIKKIEPFEKPL-FSIRTLREIKILK 64
LGEG Y V+ S+ + VAIKKI+P + I +REIK LK
Sbjct: 10 LGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIREIKSLK 69
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTL 122
+ ++ + D +F V+I+ E ++T+L VI + + ++ ++ L
Sbjct: 70 RIDSKYVVRLID-----TFVYDKCVHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMVL 124
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
R + H +IHRD+KP+N+L+ S +K+ DFGL R + R
Sbjct: 125 RGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIGNR----------------- 167
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
MT TRWYRAPE+++ + Y +D+WS GC+ AEL + PLF
Sbjct: 168 --------------MTPQAVTRWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFA 213
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALD 302
G QL +IF+ LGTP E+E + E++ ++PK + F AS+ ALD
Sbjct: 214 GDTDIQQLDMIFRALGTPVEREWPGV---STLPEFL-DFQQYPKASLNGLFSAASSDALD 269
Query: 303 LLDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPI 342
LL+++L +P RI+ +A+ HPY S P TPI
Sbjct: 270 LLEKLLTLNPCNRISCDDAIKHPYFKS------SPPPTPI 303
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 148 bits (373), Expect = 1e-35
Identities = 101/317 (31%), Positives = 165/317 (51%), Gaps = 38/317 (11%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ +G+G Y +V A+ +G+IVA+KK+ S+R + REI IL+ H
Sbjct: 138 ADSFEKLDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILRKLDH 197
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLRALK 126
N++ + Q + + ++++ E M+ DL + + + +E ++ F+ Q L L+
Sbjct: 198 PNVMKL---QCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLE 254
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H ++HRD+K SNLL+N++ LKI DFGLA
Sbjct: 255 HCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKP---------------------- 292
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
D D + T V T WYRAPE++L + +Y ++D+WS GCILAEL +P+ PG+
Sbjct: 293 --DQDQPL---TSRVVTLWYRAPELLLGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTE 347
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLD 305
+Q+ IF+ G+P+E E + +A Y P+HP K F N S+++LDLLD
Sbjct: 348 VEQMHKIFKLCGSPSE-EFWNTTKFPQATSY---KPQHPYKRVLLETFKNLSSSSLDLLD 403
Query: 306 RMLQFDPRLRITATEAL 322
++L +P R +A+ L
Sbjct: 404 KLLSVEPEKRCSASSTL 420
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 147 bits (372), Expect = 2e-35
Identities = 105/339 (30%), Positives = 175/339 (50%), Gaps = 49/339 (14%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
++G G++GVV A+ + E+VAIKK+ + F R E++I++ H NI+ +
Sbjct: 124 VIGNGSFGVVYQARLAETRELVAIKKV--LQDKRFKNR---ELQIMRKLDHCNIVRLRYF 178
Query: 78 QKPSSFEQFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKVLHG 130
SS E+ +E+Y+ + E + ++RV + +V+ ++YQ R+L +H
Sbjct: 179 FY-SSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHS 237
Query: 131 SNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
V HRD+KP NLL++ + LK+CDFG A+ +
Sbjct: 238 QGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVR------------------------- 272
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
G+P +S Y+ +R+YRAPE++ A Y+ S+DVWS GC+LAELL QP+FPG DQ
Sbjct: 273 GEPNVS----YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ 328
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNAS-AAALDLLDRML 308
L+ I + LGTPT +++ E+ N ++ + HP W + F + + A+ L +L
Sbjct: 329 LVEIIKVLGTPTREQIREMNPNYTEFKF-PQIKAHP---WTKVFKSRTPPEAIALCSSLL 384
Query: 309 QFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
++ P R++ EA +H + + P P+P F
Sbjct: 385 EYTPSSRLSPLEACAHSFFDELRCLGTQLPNNRPLPPLF 423
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 147 bits (372), Expect = 2e-35
Identities = 105/339 (30%), Positives = 175/339 (50%), Gaps = 49/339 (14%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDV 77
++G G++GVV A+ + E+VAIKK+ + F R E++I++ H NI+ +
Sbjct: 124 VIGNGSFGVVYQARLAETRELVAIKKV--LQDKRFKNR---ELQIMRKLDHCNIVRLRYF 178
Query: 78 QKPSSFEQFNEVYI--IQELMQTDLHRVI-----VTQELSEDHVQYFVYQTLRALKVLHG 130
SS E+ +E+Y+ + E + ++RV + +V+ ++YQ R+L +H
Sbjct: 179 FY-SSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHS 237
Query: 131 SNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
V HRD+KP NLL++ + LK+CDFG A+ +
Sbjct: 238 QGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVR------------------------- 272
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
G+P +S Y+ +R+YRAPE++ A Y+ S+DVWS GC+LAELL QP+FPG DQ
Sbjct: 273 GEPNVS----YICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQ 328
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNAS-AAALDLLDRML 308
L+ I + LGTPT +++ E+ N ++ + HP W + F + + A+ L +L
Sbjct: 329 LVEIIKVLGTPTREQIREMNPNYTEFKF-PQIKAHP---WTKVFKSRTPPEAIALCSSLL 384
Query: 309 QFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
++ P R++ EA +H + + P P+P F
Sbjct: 385 EYTPSSRLSPLEACAHSFFDELRCLGTQLPNNRPLPPLF 423
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 146 bits (369), Expect = 4e-35
Identities = 104/332 (31%), Positives = 164/332 (49%), Gaps = 64/332 (19%)
Query: 20 GEGAYGVVCSAKHKPSGEIVAIKK-IEPFEKPLFSIRTLREIKILKHFQHENIISIFDV- 77
GEG+YGVV ++K SG++VA+KK +E + P+ LREI++LK +H N++++ +V
Sbjct: 11 GEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVF 70
Query: 78 ---QKPSSFEQFNEVYIIQEL------MQTD-----LHRVIVTQELSEDHVQYFVYQTLR 123
+K ++ + ++ EL M +D L V L+ + Q + Q
Sbjct: 71 RRKRKMHLVFEYCDHTLLNELERNPNGMDSDSIVGRLRSVADRSRLAPKNNQIMILQC-- 128
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
IHRD+KP N+L+ +KICDFG A+I+
Sbjct: 129 ----------IHRDIKPENILITKQGIIKICDFGFAQILI-------------------- 158
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
GD T+YVATRWYRAPE+++ QY S+D+W+ GC+ AELL QPL+PG
Sbjct: 159 -----PGD----AYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPG 209
Query: 244 KDYRDQLILIFQTLG--TPTEQELVELVENRRAREYIRSLPKHPKI-NWRRRFPNASAAA 300
K DQL LI +TLG P Q + + + S+P+ + +F + A
Sbjct: 210 KSDVDQLYLIIRTLGKLIPRHQSIFK----SNGFFHGISIPEPEDMETLEEKFSDVHPVA 265
Query: 301 LDLLDRMLQFDPRLRITATEALSHPYLVSYHD 332
L+ + L+ +P R+T ++ L Y S+ +
Sbjct: 266 LNFMKGCLKMNPDDRLTCSQLLESSYFDSFQE 297
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 145 bits (367), Expect = 7e-35
Identities = 101/316 (31%), Positives = 162/316 (50%), Gaps = 42/316 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPL-FSIRTLREIKILKHFQ---HENIISI 74
LG+GAYG V + G+ A+K+I K LREI ++KH H NIIS+
Sbjct: 108 LGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISL 167
Query: 75 FDV-QKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGS 131
V + ++ +I E DLH + + + + E ++ Q +RAL LH
Sbjct: 168 KSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTH 227
Query: 132 NVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGD 191
++IHRDLKP N+LLN + +K+ DFGL++ S
Sbjct: 228 SIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNT-------------------------- 261
Query: 192 PAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLI 251
+ T V T WYR+PEV+L + Y+ ++D+W+ GCI++E+ +QPLF G++ +QL
Sbjct: 262 ---TAFTTLVVTLWYRSPEVLLQS-YYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLT 317
Query: 252 LIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFD 311
IF+ +GTP ++ E+ AR+ S P++ N + P S A++ + + L++D
Sbjct: 318 DIFKKMGTPVGKDWPS--ESVIARD---SFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYD 372
Query: 312 PRLRITATEALSHPYL 327
R++A ALSHP+L
Sbjct: 373 HSKRLSARGALSHPFL 388
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 145 bits (367), Expect = 7e-35
Identities = 104/314 (33%), Positives = 144/314 (45%), Gaps = 64/314 (20%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIE----PFEKPLFSIRTLREIKILKHFQHENIISI 74
LGEG + V A+ SGE VAIKKI+ K + +REIK+LK H+NII +
Sbjct: 11 LGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGL 70
Query: 75 FDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSN 132
DV + ++ + M TDL VI +E L H++ Q L L+ LH
Sbjct: 71 RDV-----IGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHW 125
Query: 133 VIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDP 192
++HRDLKP+NLL+N + R+V
Sbjct: 126 ILHRDLKPNNLLMNK----------MGRVV------------------------------ 145
Query: 193 AISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLIL 252
TRWYRAPE++ A Y +D+WS GCI+AELL + P+FPG+ DQL+
Sbjct: 146 ----------TRWYRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVK 195
Query: 253 IFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDP 312
IF LG PT + + E Y+ P+ + F A LDL+ M FDP
Sbjct: 196 IFNILGCPTPETWPNMTE---MNSYVIIKPQTEYMALNYYFSAAPQDLLDLMAGMWTFDP 252
Query: 313 RLRITATEALSHPY 326
R+T T++L Y
Sbjct: 253 IKRLTCTQSLQMEY 266
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 145 bits (365), Expect = 1e-34
Identities = 96/311 (30%), Positives = 152/311 (48%), Gaps = 39/311 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ-HENIISIFDV 77
+GEG + V + G A K+++ + + + LREI+ L+ H NI+ + +V
Sbjct: 10 IGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEV 69
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVTQE--LSEDHVQYFVYQTLRALKVLHGSNVIH 135
+ + +I ELM +++ +I + LSE + +++YQ ++L +H + + H
Sbjct: 70 VFD---RKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFH 126
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RD+KP N+L+ + LK+ DFG R V +
Sbjct: 127 RDVKPENILIKQDV-LKLGDFGSCRSVYSK-----------------------------Q 156
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
TEY++TRWYRAPE +LT Y+ MD+WS GC+ E+ QPLFPG + DQ+ I
Sbjct: 157 PYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHD 216
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLR 315
+GTP ++ L + ++ RA + K I N S L LL M+ +DP R
Sbjct: 217 VIGTPAQKILTKFKQS-RAMNFDFPFKKGSGIPLLT--TNLSPQCLSLLHAMVAYDPDER 273
Query: 316 ITATEALSHPY 326
I A +AL HPY
Sbjct: 274 IAAHQALQHPY 284
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 144 bits (362), Expect = 3e-34
Identities = 104/328 (31%), Positives = 153/328 (45%), Gaps = 45/328 (13%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
LGEG+Y V K + + VA+K+I E+ +RE +LK +H NI+++ D+
Sbjct: 198 LGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIV 257
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDH--VQYFVYQTLRALKVLHGSNVIHR 136
F + E + TDL + + DH V+ F++Q LR L H V+HR
Sbjct: 258 HTRETLTF-----VFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHR 312
Query: 137 DLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISG 196
D+KP NLL++ +LK+ DFGLAR S PS
Sbjct: 313 DVKPQNLLISDCGELKLADFGLARAKS------------------VPSHT---------- 344
Query: 197 MTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG-KDYRDQLILIFQ 255
+ V T WYR P+V+L + +YS S+D+W GCI E++ P FPG +D DQL IF+
Sbjct: 345 YSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFK 404
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHPKI--NWRRRFPNASAAALDLLDRMLQFDPR 313
LGTPTE + + + + K+ N+ R + + + LQ +P
Sbjct: 405 LLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGET--IANGFLQLNPE 462
Query: 314 LRITATEALSHPYLVS-----YHDPDDE 336
R+ A +AL HPY Y PD E
Sbjct: 463 QRLGADDALQHPYFAQLPKKLYELPDGE 490
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 143 bits (361), Expect = 4e-34
Identities = 107/349 (30%), Positives = 166/349 (46%), Gaps = 42/349 (12%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQHENIISIFDV 77
+G+G Y V AK SG+IVA+KK+ S++ + REI +L+ H N+I +
Sbjct: 120 IGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHPNVIKL--- 176
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSED--HVQYFVYQTLRALKVLHGSNVIH 135
Q + +Y++ E M+ DL + TQ L D V+ F+ Q L L+ H V+H
Sbjct: 177 QGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHSRGVLH 236
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RD+K SNLL++++ LKI DFGLA +
Sbjct: 237 RDIKGSNLLIDNDGILKIADFGLATFYDPKQKQT-------------------------- 270
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
MT V T WYR PE++L A Y +D+WS GCI+AELL +P+ PG+ +QL IF+
Sbjct: 271 -MTSRVVTLWYRPPELLLGATSYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFK 329
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLDRMLQFDPRL 314
G+P++ + R P+HP K F + +++ L++ +L DP
Sbjct: 330 LCGSPSD----SYWKKYRLPNATLFKPQHPYKRCVAEAFNGFTPSSVHLVETLLTIDPAD 385
Query: 315 RITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
R T+T AL+ + + P D P S + +L ++L+R
Sbjct: 386 RGTSTSALNSEFFTTEPLPCDPSSLPKYPPS----KELNVKLRDEELRR 430
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 143 bits (360), Expect = 5e-34
Identities = 103/327 (31%), Positives = 167/327 (50%), Gaps = 50/327 (15%)
Query: 18 LLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISI--- 74
+LG G++GVV AK + +A+K++ ++ RE++I++ H NII +
Sbjct: 30 VLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKR-----YKNRELQIMRAISHPNIIKLIAF 84
Query: 75 FDVQKPSSFEQFNEVYIIQELMQT--DLHRVIVTQELSEDH--VQYFVYQTLRALKVLHG 130
F PS ++ + +++ + +T D R + S + ++ + +Q RAL LH
Sbjct: 85 FHTHNPSK-DETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHS 143
Query: 131 SNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
+ V HRD+KP NLL++ LK+CDFG A+++ PS
Sbjct: 144 TGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLV-------------------PS----- 179
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
+P +S Y+ +R+YRAPE++ A Y+ +DVWS C++AEL +PLFPG +Q
Sbjct: 180 -EPNVS----YICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQ 234
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYI-RSLPKHPKINWRRRFP-NASAAALDLLDRM 307
L+ I + LGTP+ E+ + N Y+ SLP P N + A+DLL +M
Sbjct: 235 LVEIIRVLGTPSYHEISVMNPN-----YVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKM 289
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPD 334
L + P RI+A E L+HP+ DP+
Sbjct: 290 LTYVPSKRISAIEVLTHPFFDELRDPN 316
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 142 bits (357), Expect = 1e-33
Identities = 109/336 (32%), Positives = 158/336 (46%), Gaps = 74/336 (22%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFE-KPLFSIRTLREIKILKHFQHENIISIFDV 77
+GEGA+G+V AKH +GEI+A+KK+ + F + LREIK L+ + + V
Sbjct: 10 IGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYV----V 65
Query: 78 QKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVIH 135
Q + F + E M +DL V+ + L++ V+ ++ L+ + H +N++H
Sbjct: 66 QLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVH 125
Query: 136 RDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAIS 195
RDLKP+NLL++++ LKI DFGLAR+ S DG
Sbjct: 126 RDLKPANLLISASGQLKIADFGLARVFSP------------------------DGSRL-- 159
Query: 196 GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQ 255
T VATR S GCI+ ELL PLFPGK+ +QL + +
Sbjct: 160 -YTHQVATR---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLR 197
Query: 256 TLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRR--------FPNASAAALDLLDRM 307
LGTP Q EL E LP + KI+++ + P+ S ALDLL +
Sbjct: 198 ILGTPNPQVWPELTE----------LPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQF 247
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIP 343
L + P RI A++AL H Y + P P PIP
Sbjct: 248 LLYPPHQRIAASKALLHQYFFTAPLP-AHPSELPIP 282
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 140 bits (354), Expect = 2e-33
Identities = 101/339 (29%), Positives = 163/339 (47%), Gaps = 38/339 (11%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ +G G Y V AK +G IVA+KK+ S++ + REI IL+ H
Sbjct: 135 ADSFEKIDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMAREILILRRLDH 194
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALK 126
N+I + + + + +Y++ M DL + + E+ +E V+ ++ Q L L+
Sbjct: 195 PNVIKLEGLV---TSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSGLE 251
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRD+K SNLL++ L+I DFGLA
Sbjct: 252 HCHNRGVLHRDIKGSNLLIDDGGVLRIGDFGLATFFDASKRQE----------------- 294
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
MT V T WYR+PE++ +YS +D+WS GCILAELL + + PG++
Sbjct: 295 ----------MTNRVVTLWYRSPELLHGVVEYSVGVDLWSAGCILAELLAGRAIMPGRNE 344
Query: 247 RDQLILIFQTLGTPTEQELVEL-VENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLD 305
+QL I++ G+P+E+ ++ + + + + LP++ K R + + S AL LLD
Sbjct: 345 VEQLHRIYKLCGSPSEEYWKKIRLPSTHKHAHHKPLPQY-KRRIREVYKDFSPEALSLLD 403
Query: 306 RMLQFDPRLRITATEALSHPYLVSYH---DPDDEPEGTP 341
+L DP R TAT+ L + + P D P+ P
Sbjct: 404 TLLALDPAERQTATDVLMSDFFTTEPLACQPSDLPKYPP 442
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 140 bits (354), Expect = 2e-33
Identities = 94/315 (29%), Positives = 159/315 (49%), Gaps = 39/315 (12%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEK-PLFSIRTLREIKILKHFQHE 69
S +++ +GEG +G V A + VAIKK+ K ++ TLREIK L+ + E
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSE 66
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLRALKV 127
I+ I D+ + + ++ E L+ + ++ LS V+ F +Q + +
Sbjct: 67 YILDIIDI-----YPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAY 121
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
LH + ++HRD+KP+NLL++ LKI DFGLAR+ P +
Sbjct: 122 LHEAGLMHRDIKPANLLISDTDMLKIADFGLARLY-------------------FPEDES 162
Query: 188 NDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYR 247
P +S TRWYRAPE++ + +Y +D+W+ GC++AE+L PLF G
Sbjct: 163 RLYSPQVS-------TRWYRAPEILFGSQKYGTGVDMWAAGCVVAEMLRGVPLFAGTTDI 215
Query: 248 DQLILIFQTLGTPTEQELVELVENRRAREYIR-SLPKHPKINWRRRFPNAS-AAALDLLD 305
+QL +I +TLG+P + EL +Y + P I+W FP+ + A ++L+
Sbjct: 216 EQLAIIIRTLGSPRLNQWPELTS---LPDYSKIRFPNSVGIHWDNLFPSCTHAVEINLVS 272
Query: 306 RMLQFDPRLRITATE 320
++ ++P+ R+ A+E
Sbjct: 273 NLVVYNPKNRLKASE 287
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 140 bits (352), Expect = 4e-33
Identities = 99/326 (30%), Positives = 160/326 (48%), Gaps = 42/326 (12%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ +G+G Y V A+ +G+IVA+KK+ S+R + REI IL+ H
Sbjct: 144 AESFEKLDKIGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMAREILILRKLDH 203
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLRALK 126
N++ + + + +Y++ E M+ DL + T + SE ++ ++ Q R L+
Sbjct: 204 PNVMKLEGLV---TSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGLE 260
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H ++HRD+K SNLL+N+ LKI DFGLA
Sbjct: 261 HCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYR----------------------- 297
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
DGD + T V T WYRAPE++L A +Y ++D+WS GCIL EL +P+ PG+
Sbjct: 298 -GDGDLQL---TSRVVTLWYRAPELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGRTE 353
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRS--LPKHP-KINWRRRFPNASAAALDL 303
+Q+ IF+ G+P+E RRA + + P HP K F + ++AL L
Sbjct: 354 VEQMHKIFKLCGSPSEDYW------RRATLPLATSFKPSHPYKPVLAETFNHFPSSALML 407
Query: 304 LDRMLQFDPRLRITATEALSHPYLVS 329
++++L +P R +A L + +
Sbjct: 408 INKLLAIEPEKRGSAASTLRSEFFTT 433
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 139 bits (351), Expect = 5e-33
Identities = 106/345 (30%), Positives = 166/345 (47%), Gaps = 53/345 (15%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
++ F+ +G+G Y V A+ +IVA+KK+ + S++ + REI +++ H
Sbjct: 210 ANTFEKLEKIGQGTYSSVYRARDLLHNKIVALKKVRFDLNDMESVKFMAREIIVMRRLDH 269
Query: 69 ENIISIFD-VQKPSSFEQFNEVYIIQELMQTDLHRV--IVTQELSEDHVQYFVYQTLRAL 125
N++ + + P S + +Y++ E M DL + + + +E V+ ++ Q L L
Sbjct: 270 PNVLKLEGLITAPVS----SSLYLVFEYMDHDLLGLSSLPGVKFTEPQVKCYMRQLLSGL 325
Query: 126 KVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSS 185
+ H V+HRD+K SNLL++S LKI DFGLA
Sbjct: 326 EHCHSRGVLHRDIKGSNLLIDSKGVLKIADFGLATFF----------------------- 362
Query: 186 AANDGDPAIS-GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGK 244
DPA S +T +V T WYR PE++L A+ Y +D+WS GCIL EL +P+ PGK
Sbjct: 363 -----DPAKSVSLTSHVVTLWYRPPELLLGASHYGVGVDLWSTGCILGELYAGKPILPGK 417
Query: 245 DYRDQLILIFQTLGTPTE-----QELVELVENRRAREYIRSLPKHPKINWRRRFPNASAA 299
+QL IF+ G+PTE Q+L + A Y R + + F + A+
Sbjct: 418 TEVEQLHKIFKLCGSPTENYWRKQKLPSSAGFKTAIPYRRKVSE--------MFKDFPAS 469
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYH---DPDDEPEGTP 341
L LL+ +L DP R +A AL Y + DP + P+ P
Sbjct: 470 VLSLLETLLSIDPDHRSSADRALESEYFKTKPFACDPSNLPKYPP 514
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 139 bits (350), Expect = 7e-33
Identities = 103/324 (31%), Positives = 155/324 (47%), Gaps = 45/324 (13%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQHE 69
S F+ Q +G G + V A+ + VA+K+I SI+ + REI IL+ H
Sbjct: 101 SHFEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDHP 160
Query: 70 NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRV--IVTQELSEDHVQYFVYQTLRALKV 127
N+I + + + +Y+I E M+ DL + ++ SE V+ ++ Q LR L
Sbjct: 161 NVIKLEGLMLVD--HDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQLLRGLDH 218
Query: 128 LHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAA 187
H ++V+HRD+K SNLL+N + LKI DFGLA
Sbjct: 219 CHTNHVLHRDMKSSNLLINGDGVLKIADFGLATFF------------------------- 253
Query: 188 NDGDPAIS-GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
DP S +T +VAT WYR PE++L A+ Y +D+WS GC++ EL +P+ PGK+
Sbjct: 254 ---DPHNSVPLTTHVATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKNE 310
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINW----RRRFPNASAAALD 302
DQL IF+ G+P++ +L + S P P + F A+ +
Sbjct: 311 TDQLHKIFKLCGSPSDDYWTKL-------KLQLSTPLRPIYPYGSHIAETFKQFPASVIS 363
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
LL+ +L DP R TA AL Y
Sbjct: 364 LLETLLSIDPDFRGTAASALKSKY 387
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 139 bits (349), Expect = 9e-33
Identities = 104/354 (29%), Positives = 170/354 (47%), Gaps = 51/354 (14%)
Query: 2 GKRIVFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIK 61
G ++ + +F L+G G++G V A + + E +AIKKI+ ++ RE+
Sbjct: 26 GSKLDREVEIQFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDR-----FKSRELT 80
Query: 62 ILKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDL---HRVIV--TQELSEDHVQY 116
I+ H NII + +Q N + + E M DL HR +++ ++
Sbjct: 81 IMHEMDHPNIIRLLYYYV---MQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKL 137
Query: 117 FVYQTLRALKVLHGSNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXX 175
+++Q LR + LH N++HRD+KP NLL++ SN LKICDFG A+ + +
Sbjct: 138 YMFQLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRLEK----------- 186
Query: 176 XXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL 235
N P+ Y+ +R+YRAPE++ + Y S+D WS G ++ ELL
Sbjct: 187 -----NEPN-------------ITYICSRYYRAPELIFGSKNYDTSIDTWSVGTVVGELL 228
Query: 236 GKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF-- 293
P+F D L L + GTP+++++ + EY+ ++F
Sbjct: 229 HNSPIFLADSAVDILALQIKAFGTPSKEDMA-----KWNYEYVHIPYDTITGVGIQKFIG 283
Query: 294 PNASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDDE-PEGTPIPSSF 346
S + L+LL+ +++ DP+LRI EAL+ PY DP + P G PIP F
Sbjct: 284 RKLSLSTLELLNSLMKMDPKLRIKPYEALTLPYFDDLRDPHYKLPSGAPIPPLF 337
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 138 bits (348), Expect = 1e-32
Identities = 103/336 (30%), Positives = 162/336 (47%), Gaps = 41/336 (12%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQHENI 71
F+ +G+G Y V AK +G+IVA+KK+ S++ + REI +L+ H N+
Sbjct: 118 FEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPNV 177
Query: 72 ISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLRALKVLH 129
+ + + + +Y++ + M DL + + + SE V+ + Q + L+ H
Sbjct: 178 VKLEGLV---TSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCH 234
Query: 130 GSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
V+HRD+K SNLL++ LKI DFGLA I N
Sbjct: 235 SRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDP-----------------------NH 271
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
P MT V T WYRAPE++L A Y +D+WS GCILAELL +P+ PG+ +Q
Sbjct: 272 KRP----MTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTEVEQ 327
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLDRML 308
L I++ G+P+E + + + P+ P K + R F + ++L L+D +L
Sbjct: 328 LHKIYKLCGSPSE----DYWKKGKFTHGAIYKPREPYKRSIRETFKDFPPSSLPLIDALL 383
Query: 309 QFDPRLRITATEALSHPYLVSYH---DPDDEPEGTP 341
+P R TA+ AL + S +P D P+ P
Sbjct: 384 SIEPEDRQTASAALKSEFFTSEPYACEPADLPKYPP 419
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 138 bits (347), Expect = 1e-32
Identities = 109/358 (30%), Positives = 167/358 (46%), Gaps = 48/358 (13%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ ++G+G Y V A+ + +IVA+KK+ S+R + REI IL+ H
Sbjct: 143 ADSFEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILRRLNH 202
Query: 69 ENIISI--FDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALK 126
N++ + + K S +Y+I E M DL + T + Q Q L L+
Sbjct: 203 PNVMKLEGLIISKASG-----SMYLIFEYMDHDLAGLASTPGIKFSQAQ----QLLLGLE 253
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRD+K SNLLL+ N +LKI DFGL+ +
Sbjct: 254 HCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRK------------------- 294
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+T V T WYR PE++L + Y ++D+WS GCILAEL +PL PG+
Sbjct: 295 --------QPLTSRVVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGRTE 346
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLD 305
+Q+ IF+ G+P+E E R R P+HP K F + ++AL LL+
Sbjct: 347 VEQMHKIFKLCGSPSE----EYWRRSRLRHATIFKPQHPYKRCVADTFKDLPSSALALLE 402
Query: 306 RMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKDLKR 363
+L +P R TA+ AL + + P EP P +FD ++L ++ +R
Sbjct: 403 VLLAVEPDARGTASSALQSEFFTTKPFP-SEPSSLPRYQPRKEFD---AKLREEEARR 456
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 137 bits (346), Expect = 2e-32
Identities = 100/337 (29%), Positives = 168/337 (49%), Gaps = 39/337 (11%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGE-IVAIKKI-EPFEKPLFSIRTLREIKILKHFQ 67
S++++ + +G+G +G V A+ K + VA+KK+ EK F I LREI+IL+ +
Sbjct: 47 SNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLK 106
Query: 68 HENIISIFDV--QKPSSFEQFNEV-YIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTL 122
HEN++++ ++ K ++ + Y++ + + DL ++ + + S ++ + Q L
Sbjct: 107 HENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLL 166
Query: 123 RALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
L +H + ++HRD+K +N+L+ + LK+ DFGLAR S
Sbjct: 167 NGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFS------------------I 208
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
P + + + T V T WYR PE++L Y +D+W GCI+AE+ + P+
Sbjct: 209 PKNESKNR------YTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQ 262
Query: 243 GKDYRDQLILIFQTLG--TPTEQELVELVENRRAREYIRSLPKHPK--INWRRRFPNASA 298
G + QL I Q G TP VE +E ++ E LPK+ K + R R
Sbjct: 263 GNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIE----LPKNQKRRVKERLRPYVKDQ 318
Query: 299 AALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPDD 335
DLLD++L DP+ RI A AL+H + + P D
Sbjct: 319 TGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSD 355
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 136 bits (342), Expect = 6e-32
Identities = 98/349 (28%), Positives = 158/349 (45%), Gaps = 64/349 (18%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGE--IVAIKKIEPFEKPL--------FSIRTLREIKI 62
+++ + G YG V A S + + AIKK + K + S +RE+ +
Sbjct: 5 YKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMML 64
Query: 63 LKHFQHENIISIFDVQKPSSFEQFNEVYIIQELMQT-DLHRVIVTQELSEDHVQYFVYQT 121
+ QHENI+S+ V Y +L+Q H T+++ ++ ++Q
Sbjct: 65 CREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKSILWQI 124
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
+ + LH + ++HRDLKP+N+++ + +KI D GL R++
Sbjct: 125 INGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIR------------------ 166
Query: 182 SPSSAANDGDPAIS--GMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQP 239
DP + V T WYRAPE++L A Y+ ++DVW+ GCI E+L P
Sbjct: 167 ---------DPILPFYSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSP 217
Query: 240 LFPGKDYR-----------DQLILIFQTLGTPTEQELVEL--------VENRRAREYIRS 280
LF G + + Q++ I + LGTPTE+ L + + R +
Sbjct: 218 LFKGDEIKMEDKKVVPFQSTQMLRIMELLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNL 277
Query: 281 LPKHPKINWRRRFPNASAAALDLLDRMLQFDPRLRITATEALSHPYLVS 329
LP+ W + N LDLL +MLQ+DP+ RITA +AL H + S
Sbjct: 278 LPQ-----WYQTVKNRDPQGLDLLMKMLQYDPKSRITAKQALEHVFFTS 321
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 136 bits (342), Expect = 6e-32
Identities = 107/338 (31%), Positives = 157/338 (45%), Gaps = 43/338 (12%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ +G+G Y V A+ +IVA+KK+ S+R + REI+IL+ H
Sbjct: 131 ADSFEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRLDH 190
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDL-----HRVIVTQELSEDHVQYFVYQTLR 123
NII + + + +Y++ E M+ DL H I + SE V+ ++ Q L
Sbjct: 191 PNIIKLEGLV---TSRMSCSLYLVFEYMEHDLAGLASHPAI---KFSESQVKCYLQQLLH 244
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
L H V+HRD+K SNLL++++ LKI DFGLA R
Sbjct: 245 GLDHCHSRGVLHRDIKGSNLLIDNSGVLKIADFGLASFFDPRQT---------------- 288
Query: 184 SSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPG 243
+T V T WYR PE++L A +Y ++D+WS GCILAEL +P+ PG
Sbjct: 289 -----------QPLTSRVVTLWYRPPELLLGATRYGAAVDLWSAGCILAELYAGKPIMPG 337
Query: 244 KDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDL 303
+ +QL IF+ G+PTE V++R I + K F AL L
Sbjct: 338 RTEVEQLHKIFKLCGSPTED---YWVKSRLPHATIFKPTQPYKRLVGETFKEFPQPALAL 394
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDEPEGTP 341
L+ +L +P R TAT AL + + P D P P
Sbjct: 395 LETLLSVNPDDRGTATAALKSEFFSTRPLPCD-PSSLP 431
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 134 bits (336), Expect = 3e-31
Identities = 105/348 (30%), Positives = 156/348 (44%), Gaps = 59/348 (16%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+S F+ +G+G Y V A+ + +IVA+K++ L S++ + REI +++ H
Sbjct: 134 ASTFEKLEKIGQGTYSSVYKARDLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRLDH 193
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRV--IVTQELSEDHVQYFVYQTLRALK 126
N++ + + S + +Y++ E M DL + I + SE V+ ++ Q L L
Sbjct: 194 PNVLKLEGLITASVS---SSLYLVFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGLH 250
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRD+K SNLL++SN LKI DFGLA P +
Sbjct: 251 HCHSRGVLHRDIKGSNLLIDSNGVLKIADFGLATFFD-------------------PQNC 291
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+T V T WYR PE++L A Y +D+WS GCIL EL +P+ GK
Sbjct: 292 VP--------LTSRVVTLWYRPPELLLGACHYGVGVDLWSTGCILGELYSGKPILAGKTE 343
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAA------ 300
+QL IF+ G+PTE +Y R L P +R P A
Sbjct: 344 VEQLHKIFKLCGSPTE-------------DYWRKLKLPPSAAFRPALPYGRRVAEMFKDL 390
Query: 301 ----LDLLDRMLQFDPRLRITATEALSHPYLVSYH---DPDDEPEGTP 341
L LL+ +L DP R +A AL Y + DP P+ P
Sbjct: 391 PTNVLSLLEALLSIDPDRRGSAARALESEYFRTEPFACDPSSLPKYPP 438
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 133 bits (335), Expect = 4e-31
Identities = 94/290 (32%), Positives = 148/290 (50%), Gaps = 45/290 (15%)
Query: 55 RTLREIKILKHFQHENIISI---FDVQKPSSFEQFNEVYIIQELMQT--DLHRVIVTQEL 109
R RE++I++ H NII + F PS ++ + +++ + +T D R +
Sbjct: 31 RVNRELQIMRAISHPNIIKLIAFFHTHNPSK-DETHLCLLLEYMPETVFDDMRWYTRRRK 89
Query: 110 SEDH--VQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERX 166
S + ++ + +Q RAL LH + V HRD+KP NLL++ LK+CDFG A+++
Sbjct: 90 SIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLV--- 146
Query: 167 XXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWS 226
PS +P +S Y+ +R+YRAPE++ A Y+ +DVWS
Sbjct: 147 ----------------PS------EPNVS----YICSRYYRAPELVFGATHYTTKIDVWS 180
Query: 227 CGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYI-RSLPKHP 285
C++AEL +PLFPG +QL+ I + LGTP+ E+ + N Y+ SLP
Sbjct: 181 AACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNPN-----YVNHSLPNVR 235
Query: 286 KINWRRRFP-NASAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPD 334
P N + A+DLL +ML + P RI+A E L+HP+ DP+
Sbjct: 236 PHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRDPN 285
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 133 bits (335), Expect = 4e-31
Identities = 92/323 (28%), Positives = 161/323 (49%), Gaps = 45/323 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQH-EN 70
++QL LG G Y V A + + E V +K ++P +K + REIKIL++ + N
Sbjct: 38 DYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK----KIKREIKILENLRGGPN 93
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
II++ D+ K + + + TD ++ Q L++ +++++Y+ L+AL H
Sbjct: 94 IITLADIVKDPVSR--TPALVFEHVNNTDFKQLY--QTLTDYDIRFYMYEILKALDYCHS 149
Query: 131 SNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N++++ + L++ D+GLA P N
Sbjct: 150 MGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYH-------------------PGQEYN- 189
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+LA ++ K+P F G D D
Sbjct: 190 ---------VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD 240
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-----ASAAALDL 303
QL+ I + LGT + ++ + L +H + W R + S ALD
Sbjct: 241 QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF 300
Query: 304 LDRMLQFDPRLRITATEALSHPY 326
LD++L++D + R+TA EA+ HPY
Sbjct: 301 LDKLLRYDHQSRLTAREAMEHPY 323
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 133 bits (335), Expect = 4e-31
Identities = 94/315 (29%), Positives = 160/315 (49%), Gaps = 38/315 (12%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQHENI 71
FQ +G+G Y V A+ +G++VA+KK++ SIR + REI IL+ H NI
Sbjct: 105 FQKLEKIGQGTYSSVFRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLNHPNI 164
Query: 72 ISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALKVLH 129
+ + + + + +Y++ E M+ DL + ++ +E ++ ++ Q L L+ H
Sbjct: 165 MKLEGIVTSRAS---SSIYLVFEYMEHDLAGLSSNPDIRFTEPQIKCYMKQLLWGLEHCH 221
Query: 130 GSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
VIHRD+K SN+L+N+ LK+ DFGLA +V+ PS+
Sbjct: 222 MRGVIHRDIKASNILVNNKGVLKLGDFGLANVVT-------------------PSNK--- 259
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
+ +T V T WYRAPE+++ + Y S+D+WS GC+ AE+L +P+ G+ +Q
Sbjct: 260 -----NQLTSRVVTLWYRAPELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKGRTEIEQ 314
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLDRML 308
L I++ G+P + + + P+H + R R + SA + LL+ +L
Sbjct: 315 LHKIYKLCGSPQD----SFWKRTKLPHATSFKPQHTYEATLRERCKDLSATGVYLLETLL 370
Query: 309 QFDPRLRITATEALS 323
+P R TA+ AL+
Sbjct: 371 SMEPDKRGTASSALN 385
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 133 bits (334), Expect = 5e-31
Identities = 92/321 (28%), Positives = 156/321 (47%), Gaps = 38/321 (11%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ +G+G Y V A+ +G++VA+KK+ S+R + REI IL+ H
Sbjct: 153 AESFEKLDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREINILRKLDH 212
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQ--ELSEDHVQYFVYQTLRALK 126
N++ + + + + +Y++ E M+ DL + + + +E ++ ++ Q L L+
Sbjct: 213 PNVMKL---ECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLE 269
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H ++HRD+K NLL+N++ LKI DFGLA I
Sbjct: 270 HCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQD------------------- 310
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+T V T WYRAPE++L A +Y +D+WS GCIL EL +P+ PG+
Sbjct: 311 --------QPLTSRVVTLWYRAPELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGRTE 362
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLD 305
+Q+ IF+ G+P++ + + + P+ P K F N +AL L+D
Sbjct: 363 VEQMHKIFKFCGSPSD----DYWQKTKLPLATSFKPQQPYKRVLLETFKNLPPSALALVD 418
Query: 306 RMLQFDPRLRITATEALSHPY 326
++L +P R TA+ LS +
Sbjct: 419 KLLSLEPAKRGTASSTLSSKF 439
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 131 bits (330), Expect = 1e-30
Identities = 101/343 (29%), Positives = 164/343 (47%), Gaps = 46/343 (13%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
S F+ +G+G Y V A+ +G IVA+KK+ S+R + REI IL+ H
Sbjct: 128 SDAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPESVRFMAREILILRKLNH 187
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALK 126
NII + + + + ++++ E M+ DL ++ + ++ + ++ ++ Q L L
Sbjct: 188 PNIIKLEGIV---TSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQIKCYMKQLLSGLD 244
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRD+K SNLL+N+ LK+ DFGLA + A
Sbjct: 245 HCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCN----------------------A 282
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+ + P +T V T WYR PE++L A +Y S+D+WS GC+ AELL +P+ G+
Sbjct: 283 SGNKQP----LTSRVVTLWYRPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTE 338
Query: 247 RDQLILIFQTLGTPTE-----QELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
+QL IF+ G+P E +L + + + Y L + K+ S A +
Sbjct: 339 VEQLHKIFKLCGSPPEDYWKKSKLPHAMLFKPQQHYDGCLRETLKLK------GLSDADI 392
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVSYH---DPDDEPEGTP 341
+L++ +L P R TA+ AL Y S DP P +P
Sbjct: 393 NLIETLLSIQPHKRGTASTALVSQYFTSKPFACDPSSLPVYSP 435
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 131 bits (330), Expect = 1e-30
Identities = 101/339 (29%), Positives = 163/339 (47%), Gaps = 41/339 (12%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
+ F+ +G+G Y V A+ + ++VA+KK+ S+R + REI IL+ H
Sbjct: 160 ADSFEKLEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMAREIIILRRLDH 219
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALK 126
N++ + + + +Y+I E M+ DL + T + SE ++ ++ Q L L+
Sbjct: 220 PNVMKLEGL---ITSRVSGSMYLIFEYMEHDLAGLASTPGINFSEAQIKCYMKQLLHGLE 276
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRD+K SNLLL+ N +LKI DFGLA
Sbjct: 277 HCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQ----------------------- 313
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+ P +T V T WYR PE++L + Y ++D+WS GCILAEL +P+ PG+
Sbjct: 314 GHQKQP----LTSRVVTLWYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTE 369
Query: 247 RDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLD 305
+QL IF+ G+P+E E ++ + A + P+ P K F + ++AL L++
Sbjct: 370 VEQLHKIFKLCGSPSE-EYWKISKLPHATIF---KPQQPYKRCVAETFKSLPSSALALVE 425
Query: 306 RMLQFDPRLRITATEALSHPYLVS---YHDPDDEPEGTP 341
+L +P R T AL + + DP P+ P
Sbjct: 426 VLLAVEPDARGTTASALESEFFTTSPLASDPSSLPKYQP 464
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 131 bits (329), Expect = 2e-30
Identities = 78/246 (31%), Positives = 125/246 (50%), Gaps = 37/246 (15%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFDVQ 78
+GEGA+G V ++ G + AIKK+ + F +REIK+ K +++II + ++
Sbjct: 10 VGEGAFGQVYKSRRTSDGAVFAIKKMPVDRETGFPFTAIREIKLCKSVINKHIIGLDEIV 69
Query: 79 KPSSFEQFNEVYIIQELMQTDLHRVIVT-QELSEDHVQYFVYQTLRALKVLHGSNVIHRD 137
F ++++ E M DL ++ + +LS D ++ Q + A+ +HG ++HRD
Sbjct: 70 FEEGF-----IFVVLEYMPYDLTGLLASGAKLSTDQIRSITSQLIEAVSSMHGMGLVHRD 124
Query: 138 LKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGM 197
+KPSN+LL+ + LK+ DFGL R +S M
Sbjct: 125 IKPSNILLDCHGMLKLTDFGLTREIS-------------------------------GMM 153
Query: 198 TEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTL 257
T V T WYRAPE++L YS +D WS GCI+ E+ +P + G D Q+ LIF+ L
Sbjct: 154 TNRVCTLWYRAPELLLGETSYSLKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEEL 213
Query: 258 GTPTEQ 263
G P ++
Sbjct: 214 GIPQDK 219
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 129 bits (325), Expect = 5e-30
Identities = 105/351 (29%), Positives = 163/351 (45%), Gaps = 82/351 (23%)
Query: 19 LGEGAYGVVCSAKHKPSGEI--VAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFD 76
+G G YG V AK K + A+K+IE S+ REI +L+ +H N+IS+
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIEGTG---ISMSACREIALLRELKHPNVISL-- 81
Query: 77 VQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDH----------VQYFVYQTLRALK 126
QK +V+++ + + DL +I S+ + V+ +YQ L +
Sbjct: 82 -QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIH 140
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCD----LKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
LH + V+HRDLKP+N+L+ +KI D G AR+ NS
Sbjct: 141 YLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF------------------NS 182
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
P D DP V T WYRAPE++L A Y+K++D+W+ GCI AELL +P+F
Sbjct: 183 PLKPLADLDPV-------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFH 235
Query: 243 GKD---------YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKI--NWRR 291
+ + DQL IF +G P +++ E I+ +P+H + ++RR
Sbjct: 236 CRQEDIKTSNPYHHDQLDRIFNVMGFPADKDW----------EDIKKMPEHSTLMKDFRR 285
Query: 292 R-FPNAS-------------AAALDLLDRMLQFDPRLRITATEALSHPYLV 328
+ N S + A LL ++L DP RIT+ +A+ PY +
Sbjct: 286 NTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFL 336
>CE17321 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 360
Score = 129 bits (325), Expect = 5e-30
Identities = 94/324 (29%), Positives = 158/324 (48%), Gaps = 47/324 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQH-EN 70
++QL LG G Y V + E V +K ++P +K + REIKIL++ + N
Sbjct: 37 DYQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKK----KIKREIKILENLRGGTN 92
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
II++ DV K I + + +D ++ Q LS+ ++Y++Y+ L+AL H
Sbjct: 93 IITLLDVVKDPISR--TPALIFEHVNNSDFKQLY--QTLSDYDIRYYLYELLKALDFCHS 148
Query: 131 SNVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N+++++ +L++ D+GLA R
Sbjct: 149 QGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVR------------------ 190
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+LA ++ K+P F G D D
Sbjct: 191 -----------VASRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD 239
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA------SAAALD 302
QL+ I + LGT E + + L +H + W RF +A + ALD
Sbjct: 240 QLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRW-ERFIHAENQHLVTPEALD 298
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
LD++L++D R+TA EA+ H Y
Sbjct: 299 FLDKLLRYDHAERLTAQEAMGHEY 322
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 129 bits (325), Expect = 5e-30
Identities = 103/353 (29%), Positives = 161/353 (45%), Gaps = 69/353 (19%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENII 72
++ + G GA+G+V A+ + + VAIK+I + + REI L++ H NI+
Sbjct: 8 YETIQVAGRGAFGLVVIARDTLTSKRVAIKRI--MVPNVSKVSLAREISCLRNLHHRNIL 65
Query: 73 SIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGSN 132
+ D PS+ +LM IVT+E+ ++ Q L + LH
Sbjct: 66 KLLDCF-PSA-----------DLMS------IVTEEVP---YTWYYTQILSGIAYLHSKE 104
Query: 133 VIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDP 192
++HRD+KP N+L+ S +KI DFG A + DP
Sbjct: 105 IMHRDIKPENILVTSRNVVKIADFGQACFYMPK-------------------------DP 139
Query: 193 AISGMTEY---VATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQ 249
EY VATRWYRAPE++ + +Y +D+W+ GCILAEL+ +P+FPG+ +Q
Sbjct: 140 N----QEYDVNVATRWYRAPELLFGSKKYKPDVDIWAIGCILAELVRGKPIFPGRSELEQ 195
Query: 250 LILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRF--PNASAAALDLLDRM 307
+ +IF LGTP E A + + PK P+ NW S + L
Sbjct: 196 ISIIFGVLGTPNEDNWPNWRTMPDANKLLFE-PKEPRNNWTEILLCKEISNNFTEFLGSH 254
Query: 308 LQFDPRLRITATEALSHPYLVSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKD 360
LQF RL+ A+E L P++ +G P+ ++ + +R N +D
Sbjct: 255 LQFFKRLK--ASELLKEPWI---------KQGLPLVEPNYRISKKSTRRNQRD 296
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 129 bits (324), Expect = 7e-30
Identities = 108/369 (29%), Positives = 167/369 (44%), Gaps = 87/369 (23%)
Query: 19 LGEGAYGVVCSAKHKPS--GEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFD 76
+G G YG V AK K + G+ A+K+I+ S+ REI +L+ +H+N+I++
Sbjct: 104 VGRGTYGHVYKAKWKETSDGKEYALKQIDGTG---LSMSACREIALLRELKHQNVITLIR 160
Query: 77 VQKPSSFEQFNE--VYIIQELMQTDLHRVIVTQELSE----------DHVQYFVYQTLRA 124
V F N+ V+++ + + DL +I ++ V+ +YQ L
Sbjct: 161 V-----FLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDG 215
Query: 125 LKVLHGSNVIHRDLKPSNLLL----NSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXX 180
+ LH + V+HRDLKP+N+L+ N +KI D G AR+
Sbjct: 216 IHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLF------------------ 257
Query: 181 NSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPL 240
N+P D DP V T WYRAPE++L A Y+K++D+W+ GCI AELL +P+
Sbjct: 258 NAPLKPLADLDPV-------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPI 310
Query: 241 FPGKD---------YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKIN--- 288
F + + DQL IF +G P +++ E I+ +P+H +
Sbjct: 311 FHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDW----------EDIKKMPEHHTLTKDF 360
Query: 289 WRRRFPNASAA-------------ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDP-D 334
R + S A A LL ++L DP RIT+ +A+ Y P
Sbjct: 361 KRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPTQ 420
Query: 335 DEPEGTPIP 343
D G PIP
Sbjct: 421 DVFAGCPIP 429
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 128 bits (322), Expect = 1e-29
Identities = 103/349 (29%), Positives = 159/349 (45%), Gaps = 82/349 (23%)
Query: 19 LGEGAYGVVCSAKHKPSGEI--VAIKKIEPFEKPLFSIRTLREIKILKHFQHENIISIFD 76
+G G YG V A+ K + A+K+IE S+ REI +L+ +H N+I++
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVIAL-- 81
Query: 77 VQKPSSFEQFNEVYIIQELMQTDLHRVIV----------TQELSEDHVQYFVYQTLRALK 126
QK +V+++ + + DL +I +L V+ +YQ L +
Sbjct: 82 -QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIH 140
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCD----LKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
LH + V+HRDLKP+N+L+ +KI D G AR+ NS
Sbjct: 141 YLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF------------------NS 182
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
P D DP V T WYRAPE++L A Y+K++D+W+ GCI AELL +P+F
Sbjct: 183 PLKPLADLDPV-------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFH 235
Query: 243 GKD---------YRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKIN---WR 290
+ + DQL IF +G P +++ E IR +P++P + R
Sbjct: 236 CRQEDIKTSNPFHHDQLDRIFSVMGFPADKDW----------EDIRKMPEYPTLQKDFRR 285
Query: 291 RRFPNAS-------------AAALDLLDRMLQFDPRLRITATEALSHPY 326
+ N+S + LL ++L DP RIT+ +AL PY
Sbjct: 286 TTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPY 334
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 128 bits (321), Expect = 2e-29
Identities = 91/334 (27%), Positives = 162/334 (48%), Gaps = 45/334 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQH-EN 70
++QL LG G Y V A + + E V +K ++P +K + RE+KIL++ + N
Sbjct: 39 DYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK----KIKREVKILENLRGGTN 94
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
II + D K + + + + TD ++ Q L++ +++++Y+ L+AL H
Sbjct: 95 IIKLIDTVKDPVSK--TPALVFEYINNTDFKQLY--QILTDFDIRFYMYELLKALDYCHS 150
Query: 131 SNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N++++ L++ D+GLA P+ N
Sbjct: 151 KGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYH-------------------PAQEYN- 190
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+LA ++ ++P F G+D D
Sbjct: 191 ---------VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYD 241
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-----ASAAALDL 303
QL+ I + LGT ++ + L +H + W + S ALDL
Sbjct: 242 QLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDL 301
Query: 304 LDRMLQFDPRLRITATEALSHPYLVSYHDPDDEP 337
LD++L++D + R+TA EA+ HPY +P
Sbjct: 302 LDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQP 335
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 127 bits (320), Expect = 2e-29
Identities = 93/325 (28%), Positives = 159/325 (48%), Gaps = 45/325 (13%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQH-EN 70
++QL LG G Y V A + + E +K ++P +K + REIKIL++ + N
Sbjct: 36 DYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKK----KIKREIKILENLRGGTN 91
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
II++ V K I + + TD ++ Q L++ ++Y++++ L+AL H
Sbjct: 92 IITLLAVVKDPVSR--TPALIFEHVNNTDFKQLY--QTLTDYEIRYYLFELLKALDYCHS 147
Query: 131 SNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N++++ N L++ D+GLA P N
Sbjct: 148 MGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYH-------------------PGQEYN- 187
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+LA ++ K+P F G D D
Sbjct: 188 ---------VRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD 238
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPN-----ASAAALDL 303
QL+ I + LGT ++ + L +H + W R + S ALD
Sbjct: 239 QLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDF 298
Query: 304 LDRMLQFDPRLRITATEALSHPYLV 328
LD++L++D R+TA EA++HPY +
Sbjct: 299 LDKLLRYDHVDRLTAREAMAHPYFL 323
>CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 127 bits (319), Expect = 3e-29
Identities = 95/329 (28%), Positives = 149/329 (44%), Gaps = 53/329 (16%)
Query: 55 RTLREIKILKHFQHENIISIFDVQKPSSFE-QFNEVYIIQELMQTDLHRVIVTQELSEDH 113
R RE+ + + + +N++ ++ P+ + E YI++E M + + + H
Sbjct: 65 RAQRELNCMLNIEDDNVVKMYSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGH 124
Query: 114 --VQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXX 171
V+ + R ++ LH + HRDLKP N+L+N D+K+CDFG
Sbjct: 125 RTVKSIFFDICRGVQYLHAMRISHRDLKPENILMNQEGDVKLCDFG-------------- 170
Query: 172 XXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKS-MDVWSCGCI 230
+N DP + T Y+ R+YRAPE++ +K+ +D+WS GCI
Sbjct: 171 --------------HSNKEDPTSN--TPYIVQRFYRAPEIICETTDNNKTNVDIWSLGCI 214
Query: 231 LAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKH-PKINW 289
LAELL LF GKD+ DQ IL+ Q LG ++ E+ R +L ++ IN+
Sbjct: 215 LAELLTGHVLFRGKDHIDQFILMVQFLGNAGPSFYSQMNEHARNFLLRYNLDQYQAPINF 274
Query: 290 RRRFPNASAAAL------------DLLDRMLQFDPRLRITATEALSHPYL------VSYH 331
RFP+ + DLL RML +P R+ LSHPYL +
Sbjct: 275 YSRFPDTVFQGVLQFEPKECDMSRDLLFRMLVINPDDRLNIQMVLSHPYLREIWGEIVAE 334
Query: 332 DPDDEPEGTPIPSSFFQFDQWKSRLNTKD 360
D EP+ FF F + S L+ ++
Sbjct: 335 DVIPEPQPPNELLRFFDFQPYSSPLDMRE 363
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 127 bits (318), Expect = 3e-29
Identities = 96/328 (29%), Positives = 156/328 (47%), Gaps = 44/328 (13%)
Query: 10 SSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTL-REIKILKHFQH 68
S F+ +G+G Y V A +G IVA+KK+ S++ + REI IL+ H
Sbjct: 118 SDAFEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNH 177
Query: 69 ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQEL--SEDHVQYFVYQTLRALK 126
NII + + + + + ++ E M+ DL ++ + ++ + ++ ++ Q L L
Sbjct: 178 PNIIKLEGL---ITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCYMKQLLSGLD 234
Query: 127 VLHGSNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSA 186
H V+HRD+K SNLLL++ LK+ DFGLA N +S+
Sbjct: 235 HCHSRGVMHRDIKGSNLLLSNEGILKVADFGLA---------------------NFSNSS 273
Query: 187 ANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDY 246
+ P +T V T WYR PE++L A Y S+D+WS GC+ AELL +P+ G+
Sbjct: 274 GHKKKP----LTSRVVTLWYRPPELLLGATDYGASVDLWSVGCVFAELLLGKPILRGRTE 329
Query: 247 RDQLILIFQTLGTPTE-----QELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
+QL IF+ G+P E +L + + + Y L R + S +
Sbjct: 330 VEQLHKIFKLCGSPPEDYWKKSKLPHAMLFKPQQTYDSCL--------RETLKDLSETEI 381
Query: 302 DLLDRMLQFDPRLRITATEALSHPYLVS 329
+L++ +L DP R TA+ AL Y +
Sbjct: 382 NLIETLLSIDPHKRGTASSALVSQYFTT 409
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 126 bits (317), Expect = 4e-29
Identities = 82/315 (26%), Positives = 151/315 (47%), Gaps = 39/315 (12%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENI 71
E++ ++GEG +G V A+ + A+KK+ EK S+ T+RE+++L+ H +I
Sbjct: 21 EYEKIRIIGEGTFGQVILARKGRAR--YALKKVSK-EKEGLSVTTIREVQVLRAMGHPSI 77
Query: 72 ISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHGS 131
+ + +V E ++Y++ DL+R I + +++ +++ YQ + + +H
Sbjct: 78 VRLIEVV----VEPGGDIYMVFPYFPYDLNRFIRSNKMTCSEIKHIFYQIAQGVCYIHSK 133
Query: 132 NVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGD 191
++HRDLK +N+LL+ + I DFG+AR ++
Sbjct: 134 GIMHRDLKSANILLDQKLNASIADFGMARYTTK--------------------------- 166
Query: 192 PAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQLI 251
T + T WYRAPE++L ++ Y+ ++D+WS GCIL E+ +F G QL
Sbjct: 167 --TGAYTPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLE 224
Query: 252 LIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQFD 311
++ G+ E + + R + LP+ P+ A+A++L+ +ML D
Sbjct: 225 MVIHACGSINENSYPGVQDLPGFRNF--RLPQSPR-RIEGIIRKHDASAVELVSKMLCLD 281
Query: 312 PRLRITATEALSHPY 326
P RIT + + Y
Sbjct: 282 PSKRITVEQVVGSKY 296
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 126 bits (316), Expect = 6e-29
Identities = 92/325 (28%), Positives = 149/325 (45%), Gaps = 45/325 (13%)
Query: 9 ISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQH 68
I + ++G G++GVV + + + VAIKK+ + RE++ +K H
Sbjct: 160 IDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRR-----YKNRELETMKMLCH 214
Query: 69 ENIISI--FDVQKPSSFEQFNEV---YIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLR 123
N + + + +K E + + Y+ Q L Q H V + ++ ++++ YQ +
Sbjct: 215 PNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFK 274
Query: 124 ALKVLHG-SNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
AL LH + HRD+KP NLL++ + KICDFG A+ +
Sbjct: 275 ALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKP----------------- 317
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
P +S Y+ +R+YRAPE+M A YS +DVWS C++AELL +PLF
Sbjct: 318 --------DQPNVS----YICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLF 365
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAAL 301
G+ DQL+ I + +G PT+ E+ + N + P I F L
Sbjct: 366 SGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVF----PNIKPITLAEIFKAEDPDTL 421
Query: 302 DLLDRMLQFDPRLRITATEALSHPY 326
DLL + L++ P R+ + L Y
Sbjct: 422 DLLTKTLKYHPCERLVPLQCLLSSY 446
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 125 bits (313), Expect = 1e-28
Identities = 94/312 (30%), Positives = 145/312 (46%), Gaps = 58/312 (18%)
Query: 11 SEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHEN 70
+ + L +L+G G YG V A + E VA+K+I EK LREI ILK H N
Sbjct: 2 TRYILGALIGSGTYGEVYEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRN 61
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
IIS+ + + + ++ + +L + I + ++ V Q + + LH
Sbjct: 62 IISLVSIIHTDAL-----LTMVFPFIDYELKKYIGMN--TGKNIMELVNQLICGVHYLHR 114
Query: 131 SNVIHRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDG 190
NV+HRDLKP N+L+ S+ LKI DFGL+R + R
Sbjct: 115 MNVVHRDLKPQNILVTSDGVLKIADFGLSRSLEIR------------------------- 149
Query: 191 DPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFPGKDYRDQL 250
+ + V T WYR+PE+++ + Y +D+WS GCI+ E++ +PLFPG+ +QL
Sbjct: 150 ---VPPYSSEVVTLWYRSPELLMGSTSYRFYVDIWSLGCIIYEMITLEPLFPGESKENQL 206
Query: 251 ILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNASAAALDLLDRMLQF 310
LI + G T + L +VE R A +PK +++ R L F
Sbjct: 207 TLIRRKAG--TRRSLRGMVEQRLA------VPKF---------------VTEIIVRCLDF 243
Query: 311 DPRLRITATEAL 322
+ RITA E +
Sbjct: 244 NYNQRITADEIM 255
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 124 bits (310), Expect = 3e-28
Identities = 97/356 (27%), Positives = 167/356 (46%), Gaps = 73/356 (20%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ 67
+++ +++ ++G+G++G V + VA+K + ++ F + EI+IL+H +
Sbjct: 169 HLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMVRNEKR--FHRQAAEEIRILEHLK 226
Query: 68 HENIISIFDV-QKPSSFEQFNEVYIIQELMQTDLHRVIVT---QELSEDHVQYFVYQTLR 123
++ +V SF N V + EL+ DL+ +I Q S V+ F L+
Sbjct: 227 KQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQ 286
Query: 124 ALKVLHGSNVIHRDLKPSNLLL--NSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
+L LH + +IH DLKP N+LL + K+ DFG + ++
Sbjct: 287 SLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSCFEYQK---------------- 330
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
+ Y+ +R+YRAPE++L ++YS +D+WS CILAELL QPLF
Sbjct: 331 ---------------LYTYIQSRFYRAPEIIL-GSRYSTPIDIWSFRCILAELLTGQPLF 374
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRS--LPKHPKI------------ 287
PG+D DQL + + LG P + L +++RA+ +I S +P++ +
Sbjct: 375 PGEDEGDQLACMMELLGMPPPK---LLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVG 431
Query: 288 ----NWRRRFPNASA------------AALDLLDRMLQFDPRLRITATEALSHPYL 327
++R P S ++ L R L +DP R+T +AL HP++
Sbjct: 432 GRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWI 487
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 123 bits (309), Expect = 4e-28
Identities = 100/321 (31%), Positives = 148/321 (45%), Gaps = 58/321 (18%)
Query: 19 LGEGAYGVVCSAKHKPSGEIVAIK--KIEPFEKPLFSIRTLREIKILKHFQHENIISIFD 76
+GEG YG V AK+ + EIVA+K +++ + + S LREI +LK +H+NI+ + D
Sbjct: 81 IGEGTYGTVFKAKNWETHEIVALKWVRLDDNDDGVPS-SALREICLLKELKHKNIVRLHD 139
Query: 77 VQKPSSFEQFNEVYIIQELMQTDLHRVI--VTQELSEDHVQYFVYQTLRALKVLHGSNVI 134
+ ++ ++ + L + +L + V+ F++Q L+ L H NV+
Sbjct: 140 L-----LHSDKKLTLVFKFCHQHLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVL 194
Query: 135 HRDLKPSNLLLNSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAI 194
RDLKP NLL+N N +LK+ DFGL+R G P
Sbjct: 195 RRDLKPQNLLINRNGELKLADFGLSRAF---------------------------GIPIC 227
Query: 195 SGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGK-QPLFPGKDYRDQLILI 253
V A YS S+D+WS GCI AEL PLFPG D DQL I
Sbjct: 228 ---------------YVFFGAKLYSTSIDLWSAGCIFAELANAGWPLFPGNDVDDQLKRI 272
Query: 254 FQTLGTPTEQELVELVENRRAREYIRSLPKHP-KINWRRRFPNASAAALDLLDRMLQFDP 312
F LG T+++ + + + Y P +P + P SA DLL +L+ +P
Sbjct: 273 FWLLGMLTKEQWPSMTKLPDYKLY----PLYPATTSLVNIVPKLSATGRDLLQNLLKCNP 328
Query: 313 RLRITATEALSHPYLVSYHDP 333
I+A EAL +PY + P
Sbjct: 329 CQCISAEEALQYPYFSDFCPP 349
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 121 bits (303), Expect = 2e-27
Identities = 88/324 (27%), Positives = 158/324 (48%), Gaps = 47/324 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF-QHEN 70
++++ +G G Y V K+ + E IK ++P +K + REIKIL++ N
Sbjct: 33 DYEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKK----KIKREIKILQNLCGGPN 88
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
I+ ++D+ + E ++ E + + +V+ L++ ++Y++Y+ L+AL H
Sbjct: 89 IVKLYDIVRD---EHSKTPSLVFEFVNSVDFKVLYPT-LTDYDIRYYIYELLKALDFCHS 144
Query: 131 SNVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N++++ L++ D+GLA P N
Sbjct: 145 QGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYH-------------------PGKEYN- 184
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+ A ++ K+P F G D D
Sbjct: 185 ---------VRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHD 235
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA------SAAALD 302
QL+ I + LGT + + + + +H W +F NA S A+D
Sbjct: 236 QLVKIAKVLGTNELDHYLNKYQLDLDPQLEALVGRHVPKPW-SKFINADNQHLVSPEAID 294
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
LD++LQ+D + R+TA EA+ HPY
Sbjct: 295 FLDKLLQYDHQDRLTAREAMDHPY 318
>SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 332
Score = 120 bits (300), Expect = 4e-27
Identities = 94/332 (28%), Positives = 160/332 (47%), Gaps = 51/332 (15%)
Query: 6 VFNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKH 65
VF +++ +G G Y V + + IK ++P + + REIKIL++
Sbjct: 36 VFGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYK----KIKREIKILQN 91
Query: 66 FQH-ENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRA 124
NIIS+ D+ + E I + + D + T LS+ ++Y+ Y+ L+A
Sbjct: 92 LAGGPNIISLLDIVRDP--ESKTPSLIFEFVDNIDFRTLYPT--LSDYDIRYYSYELLKA 147
Query: 125 LKVLHGSNVIHRDLKPSNLLLN-SNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXNSP 183
L H ++HRD+KP N++++ L++ D+GLA
Sbjct: 148 LDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYH-------------------- 187
Query: 184 SSAANDGDPAISGMTEY---VATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQP 239
+GM EY VA+R+++ PE+++ +Y S+D+WS G + A L+ K
Sbjct: 188 -----------AGM-EYNVRVASRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDT 235
Query: 240 LFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINW-----RRRFP 294
F G+D DQL+ I + LGT V+ + R+Y L ++PK +W R
Sbjct: 236 FFRGRDNYDQLVKIAKVLGTDELFAYVQKYQIVLDRQYDNILGQYPKRDWYSFVNRDNRS 295
Query: 295 NASAAALDLLDRMLQFDPRLRITATEALSHPY 326
A+ A+DLL+R+L++D + R+T EA++HPY
Sbjct: 296 LANDEAIDLLNRLLRYDHQERLTCQEAMAHPY 327
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 120 bits (300), Expect = 4e-27
Identities = 88/324 (27%), Positives = 158/324 (48%), Gaps = 47/324 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF-QHEN 70
++++ +G G Y V + + E IK ++P +K + REIKIL++ N
Sbjct: 33 DYEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKK----KIRREIKILQNLCGGPN 88
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
I+ + DV + + I + + TD + T L++ ++Y++Y+ L+AL H
Sbjct: 89 IVKLLDVVRDQHSK--TPSLIFEYVNSTDFKVLYPT--LTDYDIRYYIYELLKALDFCHS 144
Query: 131 SNVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N++++ L++ D+GLA P N
Sbjct: 145 QGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYH-------------------PGKEYN- 184
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+ A ++ K+P F G D +D
Sbjct: 185 ---------VRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQD 235
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA------SAAALD 302
QL+ I + LGT + + + + +H + W +F NA S A+D
Sbjct: 236 QLVKIAKVLGTDELNAYLNKYQLELDTQLEALVGRHSRKPW-SKFINADNRHLVSPEAID 294
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
LD++L++D + R+TA EA++HPY
Sbjct: 295 YLDKLLRYDHQDRLTAKEAMAHPY 318
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 119 bits (298), Expect = 7e-27
Identities = 101/333 (30%), Positives = 152/333 (45%), Gaps = 76/333 (22%)
Query: 8 NISSEFQL--QSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLR-EIKILK 64
+IS+ +Q+ +LG G +G+V KH+ +G VAIK I+ P LR E+ IL+
Sbjct: 569 DISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQ 628
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE---LSEDHVQYFVYQT 121
+ H I+++ FE V+++ E + D+ +I++ E L E ++ V Q
Sbjct: 629 NLHHPGIVNL-----ECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQI 683
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSN---CDLKICDFGLARIVSERXXXXXXXXXXXXX 178
L AL+ LH N++H DLKP N+LL S +K+CDFG ARI+ E+
Sbjct: 684 LVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEK------------- 730
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCIL-AELLGK 237
S V T Y APEV L + Y++S+D+WS G I+ L G
Sbjct: 731 ----------------SFRRSVVGTPAYLAPEV-LRSKGYNRSLDMWSVGVIIYVSLSGT 773
Query: 238 QPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNAS 297
P +D DQ+ A Y P +P WR S
Sbjct: 774 FPFNEDEDINDQI--------------------QNAAFMY----PPNP---WR----EIS 802
Query: 298 AAALDLLDRMLQFDPRLRITATEALSHPYLVSY 330
A+DL++ +LQ R R + ++LSHP+L Y
Sbjct: 803 GEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDY 835
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 119 bits (298), Expect = 7e-27
Identities = 97/333 (29%), Positives = 154/333 (46%), Gaps = 76/333 (22%)
Query: 8 NISSEFQL--QSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLR-EIKILK 64
+I++ +Q+ +LG G +GVV KH+ +G VA+K I+ P LR E+ IL+
Sbjct: 544 DIATVYQIFPDEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRNEVAILQ 603
Query: 65 HFQHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE---LSEDHVQYFVYQT 121
+H I+++ FE +V+++ E + D+ +I++ E L E ++ + Q
Sbjct: 604 SLRHPGIVNL-----ECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQI 658
Query: 122 LRALKVLHGSNVIHRDLKPSNLLLNSN---CDLKICDFGLARIVSERXXXXXXXXXXXXX 178
L AL+ LH N++H DLKP N+LL S +K+CDFG ARI+ E+
Sbjct: 659 LVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEK------------- 705
Query: 179 XXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCIL-AELLGK 237
S V T Y APEV+L Y++S+D+WS G I+ L G
Sbjct: 706 ----------------SFRRSVVGTPAYLAPEVLLNQG-YNRSLDMWSVGVIMYVSLSGT 748
Query: 238 QPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNAS 297
P +D DQ ++N + +P W + S
Sbjct: 749 FPFNEDEDINDQ-------------------IQN--------AAFMYPASPW----SHIS 777
Query: 298 AAALDLLDRMLQFDPRLRITATEALSHPYLVSY 330
A A+DL++ +LQ R R + ++LSHP+L Y
Sbjct: 778 AGAIDLINNLLQVKMRKRYSVDKSLSHPWLQEY 810
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 119 bits (298), Expect = 7e-27
Identities = 95/337 (28%), Positives = 157/337 (46%), Gaps = 52/337 (15%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ 67
+I+ +++ ++G+G++G V A + VAIK I K F + + E+ IL +
Sbjct: 193 HIAFRYEILEVIGKGSFGQVIRALDHKTNTHVAIKIIR--NKKRFLNQAVVELNILDELR 250
Query: 68 HENIISIFDVQKPSSFEQFNE-VYIIQELMQTDLHRVIVTQE---LSEDHVQYFVYQTLR 123
++ +V + F + + I ELM +L+ +I S ++ F ++
Sbjct: 251 EKDADGSHNVIHMLDYTYFRKHLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIVK 310
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNS--NCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
L++L+ N+IH DLKP N+LL + +K+ DFG + V +
Sbjct: 311 CLRLLYKENIIHCDLKPENILLKQRGSSSIKVIDFGSSCYVDRKIYT------------- 357
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
Y+ +R+YR+PEV+L QY ++D+WS GCILAEL PLF
Sbjct: 358 ------------------YIQSRFYRSPEVIL-GLQYGTAIDMWSLGCILAELYTGFPLF 398
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPK-HPKINWRRRFPNASAAA 300
PG++ +QL I + LG P + L+ + RR R P+ R+R P + + A
Sbjct: 399 PGENEVEQLACIMEVLGLP-PKVLISVARRRRLFFDSRDAPRCITNTKGRKRSPGSKSLA 457
Query: 301 ----------LDLLDRMLQFDPRLRITATEALSHPYL 327
+D L R L++DP R+T EA H +L
Sbjct: 458 HILHCQDRYFIDFLQRCLEWDPAERMTPDEAAHHEFL 494
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 119 bits (297), Expect = 9e-27
Identities = 97/368 (26%), Positives = 170/368 (45%), Gaps = 54/368 (14%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ 67
+I+ +++ +G+G++G V + E+VA+K I K F + L E+KIL+ +
Sbjct: 99 HIAYRYEVLETIGKGSFGQVAKCLDHKNNELVALKIIR--NKKRFHQQALMELKILEALR 156
Query: 68 HENIISIFDVQKPSSFEQF-NEVYIIQELMQTDLHRVIVT---QELSEDHVQYFVYQTLR 123
++ + ++V F F N I EL+ +L+ ++ Q S V+ F L+
Sbjct: 157 KKDKDNTYNVVHMKDFFYFRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLK 216
Query: 124 ALKVLHGSNVIHRDLKPSNLLL--NSNCDLKICDFGLARIVSERXXXXXXXXXXXXXXXN 181
L++L +IH DLKP N++L +K+ DFG + ++
Sbjct: 217 CLQMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFGSSCYEHQKVYT------------- 263
Query: 182 SPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLF 241
Y+ +R+YR+PEV+L Y ++D+WS GCI AEL PLF
Sbjct: 264 ------------------YIQSRFYRSPEVIL-GHPYDVAIDMWSLGCITAELYTGYPLF 304
Query: 242 PGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKIN-WRRRFPNA---- 296
PG++ +QL I + LG P ++ R+ + PK+ N ++R+P++
Sbjct: 305 PGENEVEQLACIMEVLGLP-PAGFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSKDLT 363
Query: 297 ------SAAALDLLDRMLQFDPRLRITATEALSHPYLVSYHD--PDDEPEGTPIPSSFFQ 348
+ LD L R L ++P LR+T +AL H ++ + P P+ +SFF
Sbjct: 364 MVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQPRPQTLRKSNSFFP 423
Query: 349 FDQWKSRL 356
+ K ++
Sbjct: 424 SETRKDKV 431
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 117 bits (294), Expect = 2e-26
Identities = 89/328 (27%), Positives = 162/328 (49%), Gaps = 55/328 (16%)
Query: 13 FQLQSLLGEGAYGVVCSAKHKPSG---EIVAIKKIEPFEKPL--FSIRTLRE-IKILKHF 66
+ ++ LG+G++G V A+ K E VA+KK++ KP + LRE + + K
Sbjct: 21 YLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKIS 80
Query: 67 QHENIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQE---LSEDHVQYFVYQTLR 123
+H +I + + + + + ++++ E M +L ++ ++ +++ + Q +
Sbjct: 81 KHPCLIDLLE----TFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIIS 136
Query: 124 ALKVLHGSNVIHRDLKPSNLL--------LNSNCDLKICDFGLARIVSERXXXXXXXXXX 175
++ +H +HRD+KP N+L ++S +K+ DFGLAR
Sbjct: 137 GIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLAR--------------- 181
Query: 176 XXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL 235
PS ++ DP +TEYV+TRWYRAPE++L + Y+ S+D+++ GCI+ E+
Sbjct: 182 -------PSVSS---DP----LTEYVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIY 227
Query: 236 GKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSL-----PKHPKINWR 290
+PLFPG++ DQL + + LG P EL L +A+E + L P P +
Sbjct: 228 SLKPLFPGRNETDQLNRVCEILGNPGIDELDTLHYWSQAKELAKRLGFMLPPTKPYPIQK 287
Query: 291 RRFPNASAAALDLLDRMLQFDPRLRITA 318
N ++ +L ++P +R TA
Sbjct: 288 LLPQNCPEGHAKMIPCLLAWNPDVRPTA 315
>CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 398
Score = 117 bits (294), Expect = 2e-26
Identities = 95/343 (27%), Positives = 149/343 (42%), Gaps = 67/343 (19%)
Query: 55 RTLREIKILKHFQHENIISIFDVQKPSSFE-QFNEVYIIQELMQTDLHRVIVTQELSEDH 113
R RE+ + + + +N++ ++ P+ + E YI++E M + + + H
Sbjct: 65 RAQRELNCMLNIEDDNVVKMYSTFTPAENPLKMTEFYIVREYMHGTMKNLSASTFNEGGH 124
Query: 114 --VQYFVYQTLRALKVLHGSNVIHR--------------DLKPSNLLLNSNCDLKICDFG 157
V+ + R ++ LH + HR DLKP N+L+N D+K+CDFG
Sbjct: 125 RTVKSIFFDICRGVQYLHAMRISHRYFISKLVYFVTERQDLKPENILMNQEGDVKLCDFG 184
Query: 158 LARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQ 217
+N DP + T Y+ R+YRAPE++
Sbjct: 185 ----------------------------HSNKEDPTSN--TPYIVQRFYRAPEIICETTD 214
Query: 218 YSKS-MDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRARE 276
+K+ +D+WS GCILAELL LF GKD+ DQ IL+ Q LG ++ E+ R
Sbjct: 215 NNKTNVDIWSLGCILAELLTGHVLFRGKDHIDQFILMVQFLGNAGPSFYSQMNEHARNFL 274
Query: 277 YIRSLPKH-PKINWRRRFPNASAAAL------------DLLDRMLQFDPRLRITATEALS 323
+L ++ IN+ RFP+ + DLL RML +P R+ LS
Sbjct: 275 LRYNLDQYQAPINFYSRFPDTVFQGVLQFEPKECDMSRDLLFRMLVINPDDRLNIQMVLS 334
Query: 324 HPYL------VSYHDPDDEPEGTPIPSSFFQFDQWKSRLNTKD 360
HPYL + D EP+ FF F + S L+ ++
Sbjct: 335 HPYLREIWGEIVAEDVIPEPQPPNELLRFFDFQPYSSPLDMRE 377
>CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 381
Score = 117 bits (293), Expect = 3e-26
Identities = 103/350 (29%), Positives = 151/350 (42%), Gaps = 60/350 (17%)
Query: 39 VAIKKI---EPFEKPLFSIRTLREIKILKHFQHENIISIFDVQK-PSSFEQFNEVYIIQE 94
V IKK+ E F+ R RE+ H Q EN + ++ + + E+ E Y ++E
Sbjct: 43 VVIKKVVLPENFDNWQHWRRAQRELFCTLHIQEENFVKMYSIYTWVETVEEMREFYTVRE 102
Query: 95 LMQTDLHRVIVTQELSEDH--VQYFVYQTLRALKVLHGSNVIHRDLKPSNLLLNSNCDLK 152
M +L I++ DH ++ + A++ +H V HRDLKP N+L+N K
Sbjct: 103 YMDWNLRNFILSTPEKLDHKVIKSIFFDVCLAVQYMHSIRVGHRDLKPENVLINYEAIAK 162
Query: 153 ICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVM 212
I F + AN DP ++ T Y+ R+YRAPE++
Sbjct: 163 ISGF----------------------------AHANREDPFVN--TPYIVQRFYRAPEIL 192
Query: 213 LTAAQYSK-SMDVWSCGCILAELLGKQPLFPGKDYRDQLILIFQTLGTPTEQELVELVEN 271
+K S+D+WS GCILAELL + LF G+ DQ I + LG P +++ ++
Sbjct: 193 CETMDNNKPSVDIWSLGCILAELLTGKILFTGQTQIDQFFQIVRFLGNPDLSFYMQMPDS 252
Query: 272 RRAREYIRSLPKH---PKINWRRRFPNA------------SAAALDLLDRMLQFDPRLRI 316
AR + LP + N FPN+ A DLL RML +P RI
Sbjct: 253 --ARTFFLGLPMNQYQKPTNIHEHFPNSLFLDTMISEPIDCDLARDLLFRMLVINPDDRI 310
Query: 317 TATEALSHPYLVSYH-----DPDDEPEGTPIP-SSFFQFDQWKSRLNTKD 360
+ L HPYL D E + PI FF+F + KD
Sbjct: 311 DIQKILVHPYLEEVWSNIVIDNKIEEKYPPIALRRFFEFQAFSPPRQMKD 360
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 117 bits (292), Expect = 4e-26
Identities = 88/324 (27%), Positives = 157/324 (48%), Gaps = 47/324 (14%)
Query: 12 EFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF-QHEN 70
++++ +G G Y V + S E IK ++P +K + REIKIL++ N
Sbjct: 33 DYEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKKK----KIRREIKILQNLCGGPN 88
Query: 71 IISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYFVYQTLRALKVLHG 130
I+ + DV + + I + + TD + T L++ ++Y++Y+ L+AL H
Sbjct: 89 IVKLLDVVRDQHSK--TPSLIFEYVNSTDFKVLYPT--LTDYDIRYYIYELLKALDFCHS 144
Query: 131 SNVIHRDLKPSNLLLNSNC-DLKICDFGLARIVSERXXXXXXXXXXXXXXXNSPSSAAND 189
++HRD+KP N++++ L++ D+GLA P N
Sbjct: 145 QGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYH-------------------PGKEYN- 184
Query: 190 GDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELL-GKQPLFPGKDYRD 248
VA+R+++ PE+++ Y S+D+WS GC+ A ++ K+P F G D +D
Sbjct: 185 ---------VRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQD 235
Query: 249 QLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA------SAAALD 302
QL+ I + LGT + + + + +H + W +F NA S A+D
Sbjct: 236 QLVKIAKVLGTDELNAYLNKYQLELDPQLEALVGRHSRKPW-SKFINADNQHLVSPEAID 294
Query: 303 LLDRMLQFDPRLRITATEALSHPY 326
LD++L++D + R+TA EA++H Y
Sbjct: 295 FLDKLLRYDHQDRLTAKEAMAHAY 318
>Hs18581346 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 116 bits (291), Expect = 5e-26
Identities = 73/205 (35%), Positives = 106/205 (51%), Gaps = 11/205 (5%)
Query: 7 FNISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHF 66
F++ S + LG G + SA + VAIKKI P L EIKI++
Sbjct: 44 FDLDSTYMDLKPLGCGGNYLFFSAVDNDCDKRVAIKKIV-LTNPQSVKHALCEIKIIRRL 102
Query: 67 QHENIISIFDVQKPS---------SFEQFNEVYIIQELMQTDLHRVIVTQELSEDHVQYF 117
H+NI+ +F++ PS S + N VYI+QE M+TDL +V+ L E+H + F
Sbjct: 103 DHDNIVKVFEIPGPSGSQLTDDVGSLTELNSVYIVQEYMKTDLSKVLEQGPLLEEHARLF 162
Query: 118 VYQTLRALKVLHGSNVIHRDLKPSNLLLNS-NCDLKICDFGLARIVSERXXXXXXXXXXX 176
+YQ LR LK +H +NV+HRDLKP+NL +N+ + LKI DFGLARI+
Sbjct: 163 MYQLLRGLKYIHSANVLHRDLKPTNLFINTEDLVLKIGDFGLARIMDPHYSRAHELEQMQ 222
Query: 177 XXXXNSPSSAANDGDPAISGMTEYV 201
+ P + D +S + Y+
Sbjct: 223 LTLESIPVAHEEDRQELLSVIPVYI 247
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 116 bits (291), Expect = 5e-26
Identities = 103/362 (28%), Positives = 156/362 (42%), Gaps = 85/362 (23%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ 67
+I+ +++ ++G+G++G V A + VA+K + ++ F + EI+IL H +
Sbjct: 456 HIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKR--FHRQADEEIRILDHLR 513
Query: 68 HE------NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT---QELSEDHVQYFV 118
+ NII + D F N I EL+ +L+ +I Q S V+ F
Sbjct: 514 RQDSDGTHNIIHMLDY-----FNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFA 568
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSN--CDLKICDFGLARIVSERXXXXXXXXXXX 176
Y L L +L + +IH DLKP N+LL +K+ DFG + +R
Sbjct: 569 YSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYT-------- 620
Query: 177 XXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLG 236
Y+ +R+YRAPEV+L +Y +D+WS GCILAELL
Sbjct: 621 -----------------------YIQSRFYRAPEVIL-GTKYGMPIDMWSLGCILAELLT 656
Query: 237 KQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA 296
PL PG+D DQL LI + LG P + L +RAR +I S +P+ P+
Sbjct: 657 GYPLLPGEDENDQLALIIELLGMPPPKSLETA---KRARTFITS-KGYPRYCTATSMPDG 712
Query: 297 SAAA-------------------------------LDLLDRMLQFDPRLRITATEALSHP 325
S +D L R L +DP R+T +AL H
Sbjct: 713 SVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHK 772
Query: 326 YL 327
+L
Sbjct: 773 WL 774
>CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 817
Score = 116 bits (291), Expect = 5e-26
Identities = 103/362 (28%), Positives = 156/362 (42%), Gaps = 85/362 (23%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ 67
+I+ +++ ++G+G++G V A + VA+K + ++ F + EI+IL H +
Sbjct: 456 HIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKR--FHRQADEEIRILDHLR 513
Query: 68 HE------NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT---QELSEDHVQYFV 118
+ NII + D F N I EL+ +L+ +I Q S V+ F
Sbjct: 514 RQDSDGTHNIIHMLDY-----FNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFA 568
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSN--CDLKICDFGLARIVSERXXXXXXXXXXX 176
Y L L +L + +IH DLKP N+LL +K+ DFG + +R
Sbjct: 569 YSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYT-------- 620
Query: 177 XXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLG 236
Y+ +R+YRAPEV+L +Y +D+WS GCILAELL
Sbjct: 621 -----------------------YIQSRFYRAPEVIL-GTKYGMPIDMWSLGCILAELLT 656
Query: 237 KQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA 296
PL PG+D DQL LI + LG P + L +RAR +I S +P+ P+
Sbjct: 657 GYPLLPGEDENDQLALIIELLGMPPPKSLETA---KRARTFITS-KGYPRYCTATSMPDG 712
Query: 297 SAAA-------------------------------LDLLDRMLQFDPRLRITATEALSHP 325
S +D L R L +DP R+T +AL H
Sbjct: 713 SVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHK 772
Query: 326 YL 327
+L
Sbjct: 773 WL 774
>CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 508
Score = 116 bits (291), Expect = 5e-26
Identities = 103/362 (28%), Positives = 156/362 (42%), Gaps = 85/362 (23%)
Query: 8 NISSEFQLQSLLGEGAYGVVCSAKHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQ 67
+I+ +++ ++G+G++G V A + VA+K + ++ F + EI+IL H +
Sbjct: 162 HIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKR--FHRQADEEIRILDHLR 219
Query: 68 HE------NIISIFDVQKPSSFEQFNEVYIIQELMQTDLHRVIVT---QELSEDHVQYFV 118
+ NII + D F N I EL+ +L+ +I Q S V+ F
Sbjct: 220 RQDSDGTHNIIHMLDY-----FNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFA 274
Query: 119 YQTLRALKVLHGSNVIHRDLKPSNLLLNSN--CDLKICDFGLARIVSERXXXXXXXXXXX 176
Y L L +L + +IH DLKP N+LL +K+ DFG + +R
Sbjct: 275 YSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYT-------- 326
Query: 177 XXXXNSPSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLG 236
Y+ +R+YRAPEV+L +Y +D+WS GCILAELL
Sbjct: 327 -----------------------YIQSRFYRAPEVIL-GTKYGMPIDMWSLGCILAELLT 362
Query: 237 KQPLFPGKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLPKHPKINWRRRFPNA 296
PL PG+D DQL LI + LG P + L +RAR +I S +P+ P+
Sbjct: 363 GYPLLPGEDENDQLALIIELLGMPPPKSLETA---KRARTFITS-KGYPRYCTATSMPDG 418
Query: 297 SAAA-------------------------------LDLLDRMLQFDPRLRITATEALSHP 325
S +D L R L +DP R+T +AL H
Sbjct: 419 SVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHK 478
Query: 326 YL 327
+L
Sbjct: 479 WL 480
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 116 bits (290), Expect = 6e-26
Identities = 93/335 (27%), Positives = 159/335 (46%), Gaps = 60/335 (17%)
Query: 19 LGEGAYGVVCSA-----KHKPSGEIVAIKKIEPFEKPLFSIRTLREIKILKHFQHENIIS 73
+G GA+G V A K G AIKK+ P + RE++IL+ H NI+
Sbjct: 41 IGRGAFGTVVQAYLTQDKKNWLGPF-AIKKV-----PAHTEYKSRELQILRIADHPNIVK 94
Query: 74 I---FDVQKPSSFEQFNEVY------IIQELMQTDLHRVIVTQ-ELSEDHVQYFVYQTLR 123
+ F P Q N+VY + E +Q +++R + + E+ H++ + YQ R
Sbjct: 95 LQYFFTHLSP----QDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIAR 150
Query: 124 ALKVLHGSNVIHRDLKPSNLLLNSNCD-LKICDFGLARIVSERXXXXXXXXXXXXXXXNS 182
+ LHG V HRD+KPSN+L++ LKICDFG A+ +
Sbjct: 151 GMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHN----------------- 193
Query: 183 PSSAANDGDPAISGMTEYVATRWYRAPEVMLTAAQYSKSMDVWSCGCILAELLGKQPLFP 242
P+IS Y+ +R+YRAPE+++ QY+ +D+W GC++ E+L + +F
Sbjct: 194 --------QPSIS----YICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQ 241
Query: 243 GKDYRDQLILIFQTLGTPTEQELVELVENRRAREYIRSLP---KHPKINWRRRFPNASAA 299
G++ QL I + LG P ++ + N + S P + + + F ++
Sbjct: 242 GQEPLLQLREIAKLLGPPDKRFI--FFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPD 299
Query: 300 ALDLLDRMLQFDPRLRITATEALSHPYLVSYHDPD 334
+DLL ++L ++P+ R++ L+H + + D
Sbjct: 300 GIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDD 334
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,979,016
Number of Sequences: 60738
Number of extensions: 906449
Number of successful extensions: 7848
Number of sequences better than 1.0e-05: 1386
Number of HSP's better than 0.0 without gapping: 416
Number of HSP's successfully gapped in prelim test: 970
Number of HSP's that attempted gapping in prelim test: 4226
Number of HSP's gapped (non-prelim): 2353
length of query: 371
length of database: 30,389,216
effective HSP length: 108
effective length of query: 263
effective length of database: 23,829,512
effective search space: 6267161656
effective search space used: 6267161656
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)