ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2676 good C KOG2828 Energy production and conversion Acetyl-CoA hydrolase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2676 932415 933983 523
(523 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL015w [C] KOG2828 Acetyl-CoA hydrolase 891 0.0
SPAC1952.09c [C] KOG2828 Acetyl-CoA hydrolase 674 0.0
CE02538_2 [C] KOG2828 Acetyl-CoA hydrolase 73 9e-13
CE01707 [C] KOG2828 Acetyl-CoA hydrolase 71 5e-12
7301882 [C] KOG2828 Acetyl-CoA hydrolase 59 2e-08
>YBL015w [C] KOG2828 Acetyl-CoA hydrolase
Length = 526
Score = 891 bits (2302), Expect = 0.0
Identities = 431/523 (82%), Positives = 470/523 (89%)
Query: 1 MTVSRLLKDRVRYAPYLKKVKPVEELIPLFKDGQYIGWSGFTGVGAPKAVPEALIKHVEE 60
MT+S LLK RVRYAPYLKKVK ELIPLFK+GQY+GWSGFTGVG PKAVPEALI HVE+
Sbjct: 1 MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGVGTPKAVPEALIDHVEK 60
Query: 61 NNLQGKLRFNLFVGASAGPEECKWAEHDMILRRAPHQVGKPIAKAINDGRIQFFDKHLSM 120
NNLQGKLRFNLFVGASAGPEE +WAEHDMI++RAPHQVGKPIAKAIN GRI+FFDKHLSM
Sbjct: 61 NNLQGKLRFNLFVGASAGPEENRWAEHDMIIKRAPHQVGKPIAKAINQGRIEFFDKHLSM 120
Query: 121 FPQDLTYGYYSRNRTDGKILDYTIIEATAIKEDXXXXXXXXXXXXXEFISVSDKIIIEVN 180
FPQDLTYG+Y+R R D KILDYTIIEATAIKED EFI+VSDK+IIEVN
Sbjct: 121 FPQDLTYGFYTRERKDNKILDYTIIEATAIKEDGSIVPGPSVGGSPEFITVSDKVIIEVN 180
Query: 181 TATPSFEGLHDIDMPVNPPFRQPYPYTAVDQKNGLDSIPVDPERVVAVVESTQRDVVGPN 240
TATPSFEG+HDIDMPVNPPFR+PYPY VD K G+DSIPVDPE+VVA+VEST RD V PN
Sbjct: 181 TATPSFEGIHDIDMPVNPPFRKPYPYLKVDDKCGVDSIPVDPEKVVAIVESTMRDQVPPN 240
Query: 241 TPSDATSQSIARHLVEFFENEVRHGRLPENLHPLQSGIGNIANAVIEGLTDSSFKNLTVW 300
TPSD S++IA HLVEFF NEV+HGRLPENL PLQSGIGNIANAVIEGL + FK+LTVW
Sbjct: 241 TPSDDMSRAIAGHLVEFFRNEVKHGRLPENLLPLQSGIGNIANAVIEGLAGAQFKHLTVW 300
Query: 301 TEVLQDSFLDLFENGALDYATATSIRLTEAGFQKFFDNWDDFSKKLCLRSQVVSNNPELI 360
TEVLQDSFLDLFENG+LDYATATS+RLTE GF + F NW++F +LCLRSQVVSNNPE+I
Sbjct: 301 TEVLQDSFLDLFENGSLDYATATSVRLTEKGFDRAFANWENFKHRLCLRSQVVSNNPEMI 360
Query: 361 RRLGVIAMNTPVEVDIYAHANSTNVSGSRMLNGLGGSADFLRNAKLSIMHAPAARPTKTD 420
RRLGVIAMNTPVEVDIYAHANSTNV+GSRMLNGLGGSADFLRNAKLSIMHAP+ARPTK D
Sbjct: 361 RRLGVIAMNTPVEVDIYAHANSTNVNGSRMLNGLGGSADFLRNAKLSIMHAPSARPTKVD 420
Query: 421 PTGISTIVPMASHVDQTEHDLDVLVTDQGLADLRGLSPRERAREIIKNCAHPDYQPILTD 480
PTGISTIVPMASHVDQTEHDLD+LVTDQGLADLRGLSP+ERAREII CAHPDYQ +LTD
Sbjct: 421 PTGISTIVPMASHVDQTEHDLDILVTDQGLADLRGLSPKERAREIINKCAHPDYQALLTD 480
Query: 481 YLDRSEHYAKLHKCMHEPHMLKNAFKFHLNLSEKGTMKVDNWD 523
YLDR+EHYAK H C+HEPHMLKNAFKFH NL+EKGTMKVD+W+
Sbjct: 481 YLDRAEHYAKKHNCLHEPHMLKNAFKFHTNLAEKGTMKVDSWE 523
>SPAC1952.09c [C] KOG2828 Acetyl-CoA hydrolase
Length = 521
Score = 674 bits (1740), Expect = 0.0
Identities = 336/519 (64%), Positives = 398/519 (75%), Gaps = 3/519 (0%)
Query: 6 LLKDRVRYAPYLKK-VKPVEELIPLFKDGQYIGWSGFTGVGAPKAVPEALIKHVEENNLQ 64
LL R+R A + KK V +L+P FK+G Y+GWSGFTGVG PK +P AL +HVEENNLQ
Sbjct: 4 LLSSRIRNAEFAKKIVTDPAKLVPYFKNGDYVGWSGFTGVGYPKMIPNALARHVEENNLQ 63
Query: 65 GKLRFNLFVGASAGPE-ECKWAEHDMILRRAPHQVGKPIAKAINDGRIQFFDKHLSMFPQ 123
GKLRF LFVGAS G + ECKWAE +MI RR PHQVGKPI+K IN GRIQFFDKHLSMFPQ
Sbjct: 64 GKLRFKLFVGASGGADTECKWAELNMIERRCPHQVGKPISKGINSGRIQFFDKHLSMFPQ 123
Query: 124 DLTYGYYSRNRTDGKILDYTIIEATAIKEDXXXXXXXXXXXXXEFISVSDKIIIEVNTAT 183
DL YGYY+RNR + +D IIEATAI ED E + +++KIIIEVNTA
Sbjct: 124 DLLYGYYTRNR-ESNTIDTAIIEATAITEDGGIVPGASVGASPELMQLAEKIIIEVNTAI 182
Query: 184 PSFEGLHDIDMPVNPPFRQPYPYTAVDQKNGLDSIPVDPERVVAVVESTQRDVVGPNTPS 243
PSFEGLHDI NPP R P VD + G I VDP++V+ +VE+ D+ N+P
Sbjct: 183 PSFEGLHDIVEIPNPPHRTPININRVDDRIGKPYIKVDPKKVIGIVEADYGDITCANSPQ 242
Query: 244 DATSQSIARHLVEFFENEVRHGRLPENLHPLQSGIGNIANAVIEGLTDSSFKNLTVWTEV 303
D TSQ+IA HLV+FF +EV GRLP+NLHPLQSGIGNIANA+I GL S FK+L VWTEV
Sbjct: 243 DETSQAIAGHLVDFFHHEVSVGRLPKNLHPLQSGIGNIANAIIGGLAHSPFKDLEVWTEV 302
Query: 304 LQDSFLDLFENGALDYATATSIRLTEAGFQKFFDNWDDFSKKLCLRSQVVSNNPELIRRL 363
LQD+FL LF++ L +ATATS R + GF+KF+ N+D + +++ LR QV+SN+PE+IRRL
Sbjct: 303 LQDTFLPLFDSEKLRFATATSTRFSPQGFEKFYSNYDYYKERILLRPQVISNHPEIIRRL 362
Query: 364 GVIAMNTPVEVDIYAHANSTNVSGSRMLNGLGGSADFLRNAKLSIMHAPAARPTKTDPTG 423
G IAMNTPVE DIYAHANSTNV GSRMLNGLGGSADFLRNAKLSIMH P+ RP+K DPTG
Sbjct: 363 GCIAMNTPVEADIYAHANSTNVLGSRMLNGLGGSADFLRNAKLSIMHTPSVRPSKKDPTG 422
Query: 424 ISTIVPMASHVDQTEHDLDVLVTDQGLADLRGLSPRERAREIIKNCAHPDYQPILTDYLD 483
I+ IVPMA+HVDQTEHDLD+LVT+QGLADLRGLSP ERARE+I CAHPDY+P+L +Y D
Sbjct: 423 ITCIVPMATHVDQTEHDLDILVTEQGLADLRGLSPTERAREVIDKCAHPDYKPLLREYFD 482
Query: 484 RSEHYAKLHKCMHEPHMLKNAFKFHLNLSEKGTMKVDNW 522
+E+Y HEPH+L NAFK LNL EKGTMK+D+W
Sbjct: 483 IAENYCLARGAGHEPHILANAFKMQLNLLEKGTMKIDHW 521
>CE02538_2 [C] KOG2828 Acetyl-CoA hydrolase
Length = 450
Score = 73.2 bits (178), Expect = 9e-13
Identities = 68/223 (30%), Positives = 106/223 (47%), Gaps = 16/223 (7%)
Query: 267 LPENLHPLQSGIGNIANAVIEGLTDSSFKNLTVWTEVLQDSFLDLFENGALDYATATS-- 324
L +N LQ GIG + +A + L S+ K+L + TE+ D LDL E A+ A
Sbjct: 218 LVDNGATLQMGIGAVPDAALSAL--SNHKDLGIHTEMFSDGVLDLIEKNAITNAKKAIHP 275
Query: 325 ---IRLTEAGFQKFFDNWDDFSKKLCLRSQVVSNNPELIRRLG-VIAMNTPVEVDIYAHA 380
+ G K +D +D + + N+P ++R+ V A+N+ VE+D+
Sbjct: 276 GKLVVSFVYGSTKLYDYLND-NPLIEFGDVNWVNDPAVVRKNPKVTAINSAVEIDLTGQV 334
Query: 381 NSTNVSGSRMLNGLGGSADFLRNAKLSI--MHAPAARPTKTDPTGISTIVPMASH---VD 435
S +V G R L+G GG DF+R A + + P G S IVP + V
Sbjct: 335 VSDSV-GKRFLSGFGGQVDFIRGAAIGNDGLGKPIIALPSISKKGQSKIVPTINEGAGVV 393
Query: 436 QTEHDLDVLVTDQGLADLRGLSPRERAREIIKNCAHPDYQPIL 478
+ + +VT+ G+A L G + R+RA E+IK +HP + L
Sbjct: 394 TSRAHVHYVVTEYGIAQLWGKNMRQRAYELIK-ISHPSQRESL 435
>CE01707 [C] KOG2828 Acetyl-CoA hydrolase
Length = 472
Score = 70.9 bits (172), Expect = 5e-12
Identities = 84/308 (27%), Positives = 137/308 (44%), Gaps = 40/308 (12%)
Query: 196 VNPPFRQPYPYTAVDQKNGLDSIPVDPERVVAVVESTQRDVVGPNTPSDA-------TSQ 248
V+PP + VD L + ++++A+V ST G T + T +
Sbjct: 156 VSPPDELGFCTLGVDIDTTL-AAATSAKKIIALVNSTMPRTRGHTTVHSSHFAAMVQTDR 214
Query: 249 SIARHLV---EFFENEVRHGR-----LPENLHPLQSGIGNIANAVIEGLTDSSFKNLTVW 300
IA E E E R G+ L +N LQ GIG I ++ + + K+L V
Sbjct: 215 PIAFRQSGGEEMSETEQRIGKIIAENLVDNGATLQLGIGAIPDSALAAM--KQHKDLGVH 272
Query: 301 TEVLQDSFLDLFENGALDYA--------TATSIRLTEAGFQKFFDNWDDFSKKLCLRSQV 352
TE+ D +DL + G ++ T +S F K DN +F C
Sbjct: 273 TEMFSDGVIDLIDRGIINNQKKAFMPGKTVSSFAFGTKEFYKKIDNNPEFYFAPC----D 328
Query: 353 VSNNPELIRRLG-VIAMNTPVEVDIYAHANSTNVSGSRMLNGLGGSADFLRNAKLS---I 408
+N+ +++RR + ++N+ +E+D+ S ++ G +G GG DF+ + +
Sbjct: 329 FTNHIDIVRRNSKMTSINSAIEIDLTGQIVSDSI-GRNFFSGFGGQVDFMAASPHGFDGL 387
Query: 409 MHAPAARPTKTDPTGISTIVPM---ASHVDQTEHDLDVLVTDQGLADLRGLSPRERAREI 465
A A P++T G + IVP S V T +VT+ G+A+L G S R+RA E+
Sbjct: 388 GKAIIALPSRTTK-GQTKIVPFLTQGSGVVTTRAHARYIVTEHGIANLWGKSIRQRAYEL 446
Query: 466 IKNCAHPD 473
I+ +HPD
Sbjct: 447 IQ-ISHPD 453
>7301882 [C] KOG2828 Acetyl-CoA hydrolase
Length = 477
Score = 58.9 bits (141), Expect = 2e-08
Identities = 58/218 (26%), Positives = 102/218 (46%), Gaps = 20/218 (9%)
Query: 274 LQSGIGNIANAVIEGLTDSSFKNLTVWTEVLQDSFLDLFENGALDYATAT--------SI 325
LQ GIG+I +AV+ L + K+L + +E+ + ++L G + + S
Sbjct: 252 LQMGIGSIPDAVLAAL--HNHKDLGIHSEMFANGVVELVRKGCVTNSKKKMHQGRIVGSF 309
Query: 326 RLTEAGFQKFFDNWDDFSKKLCLRSQVVSNNPELIRRLGVIAMNTPVEVDIYAHANSTNV 385
+ + F DN + F + + V+N + ++ + A+N+ +EVD+ S ++
Sbjct: 310 LIGDKALYDFVDN-NPFIEMYAI--DYVNNTSIVKQQPRMTAINSCIEVDLTGQVCSDSI 366
Query: 386 SGSRMLNGLGGSADFLRNAK--LSIMHAPAARPTKTDPTGISTIVPM---ASHVDQTEHD 440
G R +G GG DF+R A L + P T G S IVP + V +
Sbjct: 367 -GPRFYSGFGGQVDFIRGAAEGLDGLGVPIIAMPSTTNKGESKIVPTLKEGAGVVTSRAH 425
Query: 441 LDVLVTDQGLADLRGLSPRERAREIIKNCAHPDYQPIL 478
+ +VT+ G+A L G + R+R E+I+ A P ++ L
Sbjct: 426 VHYVVTEHGIASLFGKNVRQRMYELIQ-IADPKHRETL 462
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,864,511
Number of Sequences: 60738
Number of extensions: 1404412
Number of successful extensions: 3254
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3245
Number of HSP's gapped (non-prelim): 6
length of query: 523
length of database: 30,389,216
effective HSP length: 111
effective length of query: 412
effective length of database: 23,647,298
effective search space: 9742686776
effective search space used: 9742686776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)