ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2730 good R KOG1573 General function prediction only Aldehyde reductase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2730 950184 949231 -318
(318 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
At5g56640 [R] KOG1573 Aldehyde reductase 241 1e-63
At4g26260 [R] KOG1573 Aldehyde reductase 231 1e-60
At2g19800 [R] KOG1573 Aldehyde reductase 216 3e-56
At1g14520 [R] KOG1573 Aldehyde reductase 215 8e-56
7294608 [R] KOG1573 Aldehyde reductase 213 4e-55
Hs20127575 [R] KOG1573 Aldehyde reductase 210 2e-54
CE16947 [R] KOG1573 Aldehyde reductase 144 2e-34
>At5g56640 [R] KOG1573 Aldehyde reductase
Length = 314
Score = 241 bits (615), Expect = 1e-63
Identities = 128/285 (44%), Positives = 178/285 (61%), Gaps = 12/285 (4%)
Query: 42 VPSKKRKMNDSTSVLDGINE--EDFRQY----NQAKDRVREFYKEQHEKQTMAYNLQARI 95
+P K +D + +N FR Y ++ + V FY QH QT+ + + R
Sbjct: 29 IPMSKISSDDEVFLAPEMNAFGRQFRDYTDTNSERQKSVEHFYATQHTNQTLDFVQKMRS 88
Query: 96 NFKTKVRARMTVWDALCQLSK-LIDESDPDTELSQIDHALQTAEAIRND-GKPRWMQLVG 153
+ + M +W+ C+LSK ++DESDPD + QI H LQ+AEAIR D W+ L
Sbjct: 89 EYGKLDKMVMNIWEC-CELSKEVVDESDPDLDEPQIQHLLQSAEAIRKDYPNEDWLHLTA 147
Query: 154 LIHDLGKILYFFESEG--QWDVVGDTFPIGCGFVKENIFPEFFQGNPDNSHPIYSTKLGI 211
LIHDLGK+L + G QW VVGDTFP+GC F + N+ ++F NPD ++P Y+TK GI
Sbjct: 148 LIHDLGKVLTLPQFGGLPQWAVVGDTFPVGCAFDESNVHHKYFMENPDFNNPKYNTKAGI 207
Query: 212 YEENSGLKSVMISWGHDEYMYYIAK-NQSTLNEKALAMIRYHSFYPWHREGAYRYLMSES 270
Y E GL++V++SWGHD+YMY +AK N STL L +IRYHSFYP H+ GAY +LM+E
Sbjct: 208 YSEGCGLENVLMSWGHDDYMYLVAKENGSTLPSPGLFIIRYHSFYPLHKAGAYTHLMNEE 267
Query: 271 DYEILEAVQDFNQYDLYSKGLQKHNRDELKPYYLELIDEFFPQKL 315
D E L+ + FN+YDLYSK N +++KPYY+ LI ++FP+ L
Sbjct: 268 DKENLKWLHVFNKYDLYSKSKVHVNVEKVKPYYMSLIKKYFPENL 312
>At4g26260 [R] KOG1573 Aldehyde reductase
Length = 318
Score = 231 bits (588), Expect = 1e-60
Identities = 119/259 (45%), Positives = 165/259 (62%), Gaps = 7/259 (2%)
Query: 64 FRQYNQAKDR---VREFYKEQHEKQTMAYNLQARINFKTKVRARMTVWDALCQLSKLIDE 120
FR Y+ +R V EFY+ QH QT+ + + R + + M++W+ L++++DE
Sbjct: 58 FRDYDVESERQKGVEEFYRLQHINQTVDFVKKMRAEYGKLDKMVMSIWECCELLNEVVDE 117
Query: 121 SDPDTELSQIDHALQTAEAIRND-GKPRWMQLVGLIHDLGKILYFFESEG--QWDVVGDT 177
SDPD + QI H LQ+AEAIR D W+ L LIHDLGK++ + G QW VVGDT
Sbjct: 118 SDPDLDEPQIQHLLQSAEAIRKDYPNEDWLHLTALIHDLGKVITLPQFGGLPQWAVVGDT 177
Query: 178 FPIGCGFVKENIFPEFFQGNPDNSHPIYSTKLGIYEENSGLKSVMISWGHDEYMYYIAK- 236
FP+GC F + N+ ++F NPD + Y+TK GIY E GL +VM+SWGHD+YMY +AK
Sbjct: 178 FPVGCAFDESNVHHKYFVENPDFHNETYNTKNGIYSEGCGLNNVMMSWGHDDYMYLVAKE 237
Query: 237 NQSTLNEKALAMIRYHSFYPWHREGAYRYLMSESDYEILEAVQDFNQYDLYSKGLQKHNR 296
N STL +IRYHSFYP H G Y +LM+E D E L+ + FN+YDLYSK +
Sbjct: 238 NGSTLPSAGQFIIRYHSFYPLHTAGEYTHLMNEEDKENLKWLHVFNKYDLYSKSKVHVDV 297
Query: 297 DELKPYYLELIDEFFPQKL 315
+++KPYY+ LI ++FP+ L
Sbjct: 298 EKVKPYYMSLIKKYFPENL 316
>At2g19800 [R] KOG1573 Aldehyde reductase
Length = 272
Score = 216 bits (551), Expect = 3e-56
Identities = 110/233 (47%), Positives = 153/233 (65%), Gaps = 4/233 (1%)
Query: 81 QHEKQTMAYNLQARINFKTKVRARMTVWDALCQLSKLIDESDPDTELSQIDHALQTAEAI 140
QH QT + + R + + M++W+ L+ ++DESDPD + QI H LQTAEAI
Sbjct: 2 QHIHQTYDFVKKMRKEYGKLNKMEMSIWECCELLNNVVDESDPDLDEPQIQHLLQTAEAI 61
Query: 141 RNDGKPR-WMQLVGLIHDLGKILYFFESEG--QWDVVGDTFPIGCGFVKENIFPEFFQGN 197
R D W+ L LIHDLGK+L E G QW VVGDTFP+GC F NI ++F+GN
Sbjct: 62 RRDYPDEDWLHLTALIHDLGKVLLLPEFGGLPQWAVVGDTFPVGCTFDSANIHHKYFKGN 121
Query: 198 PDNSHPIYSTKLGIYEENSGLKSVMISWGHDEYMYYIA-KNQSTLNEKALAMIRYHSFYP 256
D ++P Y+TK G+Y E GL +V++SWGHD+YMY +A KN +TL L +IRYHSFYP
Sbjct: 122 HDINNPKYNTKNGVYTEGCGLDNVLMSWGHDDYMYLVAKKNGTTLPHAGLFIIRYHSFYP 181
Query: 257 WHREGAYRYLMSESDYEILEAVQDFNQYDLYSKGLQKHNRDELKPYYLELIDE 309
H+ GAY +LM++ D + L+ + FN+YDLYSK + +++KPYY+ LI++
Sbjct: 182 LHKAGAYTHLMNDEDRDDLKWLHVFNKYDLYSKSKVLVDVEQVKPYYISLINK 234
>At1g14520 [R] KOG1573 Aldehyde reductase
Length = 371
Score = 215 bits (547), Expect = 8e-56
Identities = 106/212 (50%), Positives = 145/212 (68%), Gaps = 4/212 (1%)
Query: 102 RARMTVWDALCQLSKLIDESDPDTELSQIDHALQTAEAIRNDGKPR-WMQLVGLIHDLGK 160
R M++W+ L++ IDESDPD + QI+H LQTAEAIR D W+ L GLIHDLGK
Sbjct: 10 RTEMSIWECCELLNEFIDESDPDLDEPQIEHLLQTAEAIRKDYPDEDWLHLTGLIHDLGK 69
Query: 161 ILYF--FESEGQWDVVGDTFPIGCGFVKENIFPEFFQGNPDNSHPIYSTKLGIYEENSGL 218
+L F QW VVGDTFP+GC F + + ++F+ NPD +P Y++K GIY E GL
Sbjct: 70 VLLHSSFGELPQWAVVGDTFPVGCAFDESIVHHKYFKENPDYDNPSYNSKYGIYTEGCGL 129
Query: 219 KSVMISWGHDEYMYYIAK-NQSTLNEKALAMIRYHSFYPWHREGAYRYLMSESDYEILEA 277
+V++SWGHD+YMY +AK NQ+TL L +IRYHSFY H+ AY++LM+ D E ++
Sbjct: 130 DNVLMSWGHDDYMYLVAKENQTTLPSAGLFIIRYHSFYALHKSEAYKHLMNNEDRENMKW 189
Query: 278 VQDFNQYDLYSKGLQKHNRDELKPYYLELIDE 309
++ FN+YDLYSK + N +E+KPYYL L ++
Sbjct: 190 LKVFNKYDLYSKSKVRVNVEEVKPYYLSLTNK 221
>7294608 [R] KOG1573 Aldehyde reductase
Length = 275
Score = 213 bits (541), Expect = 4e-55
Identities = 114/261 (43%), Positives = 162/261 (61%), Gaps = 9/261 (3%)
Query: 60 NEEDFRQYNQ-----AKDRVREFYKEQHEKQTMAYNLQARINFKTKVRARMTVWDALCQL 114
N FR Y+ K+RVR+ Y++ H QT+ + R ++ +MTV +AL +L
Sbjct: 11 NPSKFRDYSMDTTDPLKERVRQTYRQMHLNQTVDFVKGRREHWLKFNTIKMTVREALEKL 70
Query: 115 SKLIDESDPDTELSQIDHALQTAEAIRNDGKPR-WMQLVGLIHDLGKILYFFESEGQWDV 173
+ L+DESDPD +L I HA Q AE R + W+ L LIHDLGKI+ F+ E QW V
Sbjct: 71 NDLVDESDPDLDLPNIIHAFQAAERARAEFPEHDWLHLTALIHDLGKIMAFY-GEPQWAV 129
Query: 174 VGDTFPIGCGFVKENIF-PEFFQGNPDNSHPIYSTKLGIYEENSGLKSVMISWGHDEYMY 232
VGDTF +GC + ++ E F+GNPD +P Y+T+LGIY+ N G+ ++++SWGHDEYMY
Sbjct: 130 VGDTFAVGCRWGDSIVYRDESFEGNPDGDNPAYNTELGIYQPNCGVDNLLMSWGHDEYMY 189
Query: 233 YIAK-NQSTLNEKALAMIRYHSFYPWHREGAYRYLMSESDYEILEAVQDFNQYDLYSKGL 291
+ K N++ L A +IR+HSFYPWH G Y++L + D E + V FN+YDLY+K
Sbjct: 190 SVLKHNKTKLPHVACNIIRFHSFYPWHNGGDYKHLEAPQDAETKKWVLIFNRYDLYTKSE 249
Query: 292 QKHNRDELKPYYLELIDEFFP 312
+ + L PYY LID++ P
Sbjct: 250 VVPDIEALWPYYQTLIDKYLP 270
>Hs20127575 [R] KOG1573 Aldehyde reductase
Length = 285
Score = 210 bits (534), Expect = 2e-54
Identities = 116/258 (44%), Positives = 155/258 (59%), Gaps = 6/258 (2%)
Query: 60 NEEDFRQYNQAK--DRVREFYKEQHEKQTMAYNLQARINFKTKVRARMTVWDALCQLSKL 117
++ FR Y DRV YK H QT+ + F +MTV +A+ L L
Sbjct: 24 DKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKHAQFGGFSYKKMTVMEAVDLLDGL 83
Query: 118 IDESDPDTELSQIDHALQTAEAIRNDGKPR-WMQLVGLIHDLGKILYFFESEGQWDVVGD 176
+DESDPD + HA QTAE IR + W LVGL+HDLGK+L F E QW VVGD
Sbjct: 84 VDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALF-GEPQWAVVGD 142
Query: 177 TFPIGCGFVKENIFPEF-FQGNPDNSHPIYSTKLGIYEENSGLKSVMISWGHDEYMYYIA 235
TFP+GC +F + FQ NPD P YST+LG+Y+ + GL V++SWGHDEYMY +
Sbjct: 143 TFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRVLMSWGHDEYMYQVM 202
Query: 236 K-NQSTLNEKALAMIRYHSFYPWHREGAYRYLMSESDYEILEAVQDFNQYDLYSKGLQKH 294
K N+ +L +A MIR+HSFYPWH Y+ L S+ D +L V++FN++DLY+K
Sbjct: 203 KFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDLAMLPWVREFNKFDLYTKCPDLP 262
Query: 295 NRDELKPYYLELIDEFFP 312
+ D+L+PYY LID++ P
Sbjct: 263 DVDKLRPYYQGLIDKYCP 280
>CE16947 [R] KOG1573 Aldehyde reductase
Length = 323
Score = 144 bits (363), Expect = 2e-34
Identities = 71/175 (40%), Positives = 109/175 (61%), Gaps = 3/175 (1%)
Query: 63 DFRQYNQAKDRVREFYKEQHEKQTMAYNLQARINFKTKVRARMTVWDALCQLSKLIDESD 122
D + + + RVR Y QH+KQT+ + + + A+M + L L+ +DESD
Sbjct: 150 DVKAEDPIQVRVRTHYFTQHQKQTVDFVKEMHQKWLKFDHAKMPILGCLDMLATFLDESD 209
Query: 123 PDTELSQIDHALQTAEAIRNDGKPR-WMQLVGLIHDLGKILYFFESEGQWDVVGDTFPIG 181
PD + + + HA QTAE IR + + WM L GLIHDLGKI+ + E QW V GDT+P+G
Sbjct: 210 PDVDEANLIHAYQTAEKIRENHPDKPWMHLAGLIHDLGKIMSVWGEE-QWAVTGDTYPVG 268
Query: 182 CGFVKENIFPEF-FQGNPDNSHPIYSTKLGIYEENSGLKSVMISWGHDEYMYYIA 235
C ++ + F GNPD SHP+Y T++G+Y+E G+++++++W HDEYMY ++
Sbjct: 269 CAPAASIVYGKSSFDGNPDISHPVYGTQMGMYQEKCGMENLLMTWSHDEYMYKVS 323
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,960,119
Number of Sequences: 60738
Number of extensions: 886005
Number of successful extensions: 2813
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2783
Number of HSP's gapped (non-prelim): 8
length of query: 318
length of database: 30,389,216
effective HSP length: 106
effective length of query: 212
effective length of database: 23,950,988
effective search space: 5077609456
effective search space used: 5077609456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)