ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2910 good O KOG2100 Posttranslational modification, protein turnover, chaperones Dipeptidyl aminopeptidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2910 1008460 1010946 829
(829 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR028c [O] KOG2100 Dipeptidyl aminopeptidase 961 0.0
SPACUNK4.08 [O] KOG2100 Dipeptidyl aminopeptidase 503 e-142
YOR219c [O] KOG2100 Dipeptidyl aminopeptidase 422 e-117
7297021 [O] KOG2100 Dipeptidyl aminopeptidase 307 4e-83
Hs18765694 [O] KOG2100 Dipeptidyl aminopeptidase 296 7e-80
Hs16933540 [O] KOG2100 Dipeptidyl aminopeptidase 293 1e-78
7294364 [O] KOG2100 Dipeptidyl aminopeptidase 275 2e-73
Hs22041021 [O] KOG2100 Dipeptidyl aminopeptidase 273 1e-72
Hs18765698 [O] KOG2100 Dipeptidyl aminopeptidase 267 6e-71
Hs18765696 [O] KOG2100 Dipeptidyl aminopeptidase 267 6e-71
CE21195 [O] KOG2100 Dipeptidyl aminopeptidase 219 2e-56
CE21196 [O] KOG2100 Dipeptidyl aminopeptidase 218 2e-56
SPAC14C4.15c [O] KOG2100 Dipeptidyl aminopeptidase 211 3e-54
7301225 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-pep... 211 5e-54
CE05324 [O] KOG2100 Dipeptidyl aminopeptidase 194 6e-49
7293308 [O] KOG2100 Dipeptidyl aminopeptidase 177 5e-44
At5g24260 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-p... 166 2e-40
Hs18450280 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-... 163 9e-40
Hs21040237 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-... 158 3e-38
CE28837 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-pep... 118 3e-26
CE17153 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-pep... 118 3e-26
Hs18450278 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-... 69 3e-11
SPBC1711.12 [O] KOG2100 Dipeptidyl aminopeptidase 58 5e-08
7289544 [O] KOG2100 Dipeptidyl aminopeptidase 55 3e-07
>YHR028c [O] KOG2100 Dipeptidyl aminopeptidase
Length = 818
Score = 961 bits (2485), Expect = 0.0
Identities = 463/774 (59%), Positives = 587/774 (75%), Gaps = 13/774 (1%)
Query: 62 NNGSGPRLPNKQIDYTKDGLLKVSFANVRNRTFQPEVKPLQWISTPDSHKNDKGLYVTFE 121
++ + P +YT DG LKVSF+ VRN TFQP+ LQWIS ND GLYVTF
Sbjct: 50 HHSNTPDYQEPNSNYTNDGKLKVSFSVVRNNTFQPKYHELQWISDNKIESNDLGLYVTFM 109
Query: 122 NDTYSVRSVLDESYSKTLFEGTSFTYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTF 181
ND+Y V+SV D+SY+ L EG +F ++ +N TV+++ ASP+L ++LIR+ + + WRHSTF
Sbjct: 110 NDSYVVKSVYDDSYNSVLLEGKTFIHNGQNLTVESITASPDLKRLLIRTNSVQNWRHSTF 169
Query: 182 GTYFVYE--NDSFHKIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSE 239
G+YFVY+ + SF +I +E+++A WSPNS DI YV+ N+IY+YS+ S +T + +TNDGS
Sbjct: 170 GSYFVYDKSSSSFEEIGNEVALAIWSPNSNDIAYVQDNNIYIYSAISKKTIRAVTNDGSS 229
Query: 240 LVFNGKPDWVYEEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYP 299
+FNGKPDWVYEEEV E D A WWSPTGDYLAF KI+E+ V EF IPY+VQ+ + YP
Sbjct: 230 FLFNGKPDWVYEEEVFEDDKAAWWSPTGDYLAFLKIDESEVGEFIIPYYVQDEK--DIYP 287
Query: 300 ELRKIKYPKSGSSNPINKLNIYDLSADKVS---QIDSTSDDS--LITEVTWVGNHEIIAK 354
E+R IKYPKSG+ NP +L +Y + D S +I D LITEVTWVGN ++ K
Sbjct: 288 EMRSIKYPKSGTPNPHAELWVYSMK-DGTSFHPRISGNKKDGSLLITEVTWVGNGNVLVK 346
Query: 355 VSDRSSDILTVIMVDAADGSRSEVSRIEESDGGWWEITHKTTFVPKDKSRSRSYNGYIDL 414
+DRSSDILTV ++D S V R E S+GGWWEITH T F+P +++ R +NGY+D+
Sbjct: 347 TTDRSSDILTVFLIDTI-AKTSNVVRNESSNGGWWEITHNTLFIPANETFDRPHNGYVDI 405
Query: 415 VPVDGYNHLVYFTTNVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTERHL 474
+P+ GYNHL YF + ++ + LT G+WEVV+GP AFD N +YFI+T+KSSTERH+
Sbjct: 406 LPIGGYNHLAYFENSNSSHYKT--LTEGKWEVVNGPLAFDSMENRLYFISTRKSSTERHV 463
Query: 475 YYVNLERPQKVYAVTDERLNGYYSASFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNI 534
YY++L P ++ VTD +G Y SFS+G RF LL Y GP VPYQKI+D S +K
Sbjct: 464 YYIDLRSPNEIIEVTDTSEDGVYDVSFSSGRRFGLLTYKGPKVPYQKIVDFHSRKAEKCD 523
Query: 535 RGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDP 594
+GN++GK+LY+LEKNE L L+ YA+P + FREL LGKD+ G DI+VNSYEILPNDFD
Sbjct: 524 KGNVLGKSLYHLEKNEVLTKILEDYAVPRKSFRELNLGKDEFGKDILVNSYEILPNDFDE 583
Query: 595 SLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKGKEFRSIV 654
+L +HYPVFFFAYGGPNSQQV +TF +GFN+V+ASQL+AIVVVVDGRGTGFKG++FRS+V
Sbjct: 584 TLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIVVVVDGRGTGFKGQDFRSLV 643
Query: 655 RGNLGDVESTDQILAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSV 714
R LGD E+ DQI AA LYG ++V+ +KISLFGWSYGGYLTLKTLEKD G+HFKYG+SV
Sbjct: 644 RDRLGDYEARDQISAASLYGSLTFVDPQKISLFGWSYGGYLTLKTLEKDGGRHFKYGMSV 703
Query: 715 APVTDWLLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQN 774
APVTDW YDSVYTERYMHTPQ+N +GY + VHN TA A RFLLMHGT DDNVHFQN
Sbjct: 704 APVTDWRFYDSVYTERYMHTPQENFDGYVESSVHNVTALAQANRFLLMHGTGDDNVHFQN 763
Query: 775 SLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNWIRHAYNGDFL 828
SLK+LDLL+LN +ENYDVHVFPDSDHSI+YHNANVIVF+K+L+W + A++G F+
Sbjct: 764 SLKFLDLLDLNGVENYDVHVFPDSDHSIRYHNANVIVFDKLLDWAKRAFDGQFV 817
>SPACUNK4.08 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 793
Score = 503 bits (1294), Expect = e-142
Identities = 295/759 (38%), Positives = 425/759 (55%), Gaps = 56/759 (7%)
Query: 84 VSFANVRNRTFQPEVKPLQWISTPDSHKNDKGLYVTFENDTYSVRSVLDE-SYSKTLFEG 142
+S ++ + ++P K + WI + +GL TF + ++ D + +KTLF
Sbjct: 55 LSLDDIVLQKYKPSYKQVNWIDS-------QGLKDTFLVKYGDLINIQDPYNLNKTLFSV 107
Query: 143 TSFTYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYENDS----FHKIDSE 198
+ Y+ D+ S + VL+ + WRHS+F Y++Y ++ D+E
Sbjct: 108 SDLVYNGIQLDYDSYSISFDAKYVLVSVNKSQRWRHSSFAQYYLYNTETKDVNMLGQDNE 167
Query: 199 ---ISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSELVFNGKPDWVYEEEVL 255
IS+A+WSP + +V ND+Y+ +D + +R+T DG+ VFNG DW+YEEEVL
Sbjct: 168 HWTISLAEWSPTGHQLSFVYNNDLYVRKNDGNV--QRLTYDGTVDVFNGLTDWIYEEEVL 225
Query: 256 EGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRK---IKYPKSGSS 312
+ +WWSP D +AF K+NE+ + + P + E + + K IKYPK G+
Sbjct: 226 SSPSTIWWSPDSDKIAFLKLNESEIPTYHYPLYTAELDPSLPEFDYNKDMAIKYPKPGNP 285
Query: 313 NPINKLNIYDLSADKVSQIDSTSDDSL----ITEVTWVGNHEIIAKVSDRSSDILTVIMV 368
NP L + DL+++ S ++ L + V WV ++ + ++R+S +T ++
Sbjct: 286 NPSVSLFVADLNSNASSNFSLWHNEPLAEPVVQNVLWVNTSSVLVQFTNRNSTCITARLL 345
Query: 369 DAADGSRSEVSRIEESDGGWWEITHKTTFVPKDKSR--SRSYNGYIDLVPVDGYNHLVYF 426
D S V + E + GW+E+ P + S +GY D++ +D YNHL +
Sbjct: 346 DTELKSIHTV-KTECLEEGWYEVQQSAKMFPLNNSLVWENWSDGYFDILALDDYNHLAFI 404
Query: 427 TTNVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVNLERPQKVY 486
N ++ I LTSG W+V DGP D +F NVYF+AT K STERHLYYV+L+ + +Y
Sbjct: 405 PFNGSSPI---YLTSGAWDVTDGPIHIDGDFGNVYFLATLKDSTERHLYYVSLDTLE-IY 460
Query: 487 AVTDERLN-GYYSASFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNIRGNIIGKTLYY 545
+TD + GYYS SFS F +LNY GPDVP+Q++ TKDK+
Sbjct: 461 GITDNGEDEGYYSTSFSPFGDFYVLNYHGPDVPWQEL----RSTKDKDY--------CLS 508
Query: 546 LEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFF 605
LE N +L L +P+ + +LT +D N E P +FD + K YPV FF
Sbjct: 509 LETNSRLKQQLSSITLPSVEYGKLTF------NDTTFNFMERRPRNFDVNKK--YPVLFF 560
Query: 606 AYGGPNSQQVAQTFGIGFNQVIASQLDA--IVVVVDGRGTGFKGKEFRSIVRGNLGDVES 663
AYGGP SQQVA+ F + F +AS D IVV +DGRGTGF G FR V +LG+ ES
Sbjct: 561 AYGGPGSQQVAKLFRVDFQAYLASHPDFEFIVVTLDGRGTGFNGNAFRYSVSRHLGEWES 620
Query: 664 TDQILAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLY 723
DQ A K + +V++ + ++GWSYGGYLTLKTLE F YG++VAPVTDW LY
Sbjct: 621 YDQGQAGKFWADLPFVDENHVGIWGWSYGGYLTLKTLETQ--DVFSYGMAVAPVTDWRLY 678
Query: 724 DSVYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLN 783
DSVYTERYM PQ N EGY ++H+ F + RF + HGT DDNVHFQ+S+ +D LN
Sbjct: 679 DSVYTERYMDLPQYNKEGYKNSQIHDYEKFKQLKRFFVAHGTGDDNVHFQHSMHLMDGLN 738
Query: 784 LNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNWIRHA 822
L N NYD+ VFPDS HSI YHNA++ +++++ WI A
Sbjct: 739 LANCYNYDMAVFPDSAHSISYHNASLSIYHRLSEWIGDA 777
>YOR219c [O] KOG2100 Dipeptidyl aminopeptidase
Length = 931
Score = 422 bits (1084), Expect = e-117
Identities = 263/777 (33%), Positives = 400/777 (50%), Gaps = 51/777 (6%)
Query: 80 GLLKVSFANVRNRTFQPEVKPLQWISTPD---SHKNDKGLYVTFE----NDTYSVRSVLD 132
G S NV N F +I P +D GLY T + + + + + D
Sbjct: 161 GKRSFSIENVLNGDFAIPEDTFHFIDPPQRLLGQDSDPGLYFTTKEIDGHTNFIAKQLFD 220
Query: 133 ESYSKTLFEGTSFTYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYE---- 188
E++ L G F Y+ +TV V + +L K++ + E +RHS+ G Y++ +
Sbjct: 221 ETFEVNL-GGNRFLYEGVEFTVSTVQINYKLDKLIFGTNLESEFRHSSKGFYWIKDLNTG 279
Query: 189 -----------NDSFHKIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDG 237
+D++ S++S A +SP I +V N+++L +S +K++T DG
Sbjct: 280 NIEPILPPEKSDDNYELGLSKLSYAHFSPAYNYIYFVYENNLFLQQVNSG-VAKKVTEDG 338
Query: 238 SELVFNGKPDWVYEEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSA 297
S+ +FN KPDW+YEEEVL D A+WW+P F + N+TSV++ + + N+ A
Sbjct: 339 SKDIFNAKPDWIYEEEVLASDQAIWWAPDDSKAVFARFNDTSVDDIRLNRYTNMNE---A 395
Query: 298 YPELRKIKYPKSGSSNPINKLNIYDLSADKVSQIDSTSD-DSLITEVTWVGNHEIIAKVS 356
Y KIKYPK G NP L + +L + I++ DS++ W+ +++
Sbjct: 396 YLSDTKIKYPKPGFQNPQFDLFLVNLQNGIIYSINTGGQKDSILYNGKWISPDTFRFEIT 455
Query: 357 DRSSDILTVIMVDAADGSRSEVSRIEES-DGGWWEITHKTTFVPKDKSRSRSYNGYIDL- 414
DR+S IL V + D V + GW E T +P R GYID+
Sbjct: 456 DRNSKILDVKVYDIPSSQMLTVRNTNSNLFNGWIEKTKDILSIPPKPELKRMDYGYIDIH 515
Query: 415 VPVDGYNHLVYFTTNVTTEIPSVVLTSGEWEVV-DGPAAFDEEFNNVYFIATKKSSTERH 473
G++HL Y+ T E + LT G WEV +G ++ E + ++F A + +H
Sbjct: 516 ADSRGFSHLFYYPTVFAKE--PIQLTKGNWEVTGNGIVGYEYETDTIFFTANEIGVMSQH 573
Query: 474 LYYVNL--ERPQKVYAVTDERLNGY--YSASFSAGARFLLLNYLGPDVPYQKIIDLKSDT 529
LY ++L Q + + Y Y S+ AR+ + LGPD P + L T
Sbjct: 574 LYSISLTDSTTQNTFQSLQNPSDKYDFYDFELSSSARYAISKKLGPDTPIKVAGPL---T 630
Query: 530 KDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILP 589
+ N+ I ++ L K+EK +K Y +P ++ + L + +N EI P
Sbjct: 631 RVLNV-AEIHDDSILQLTKDEKFKEKIKNYDLPITSYKTMVLD-----DGVEINYIEIKP 684
Query: 590 NDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKGKE 649
+ +P K YP+ YGGP SQ + F Q + S LD IV+ ++ RGTG KG
Sbjct: 685 ANLNP--KKKYPILVNIYGGPGSQTFTTKSSLAFEQAVVSGLDVIVLQIEPRGTGGKGWS 742
Query: 650 FRSIVRGNLGDVESTDQILAAKLYGQNS--YVNKEKISLFGWSYGGYLTLKTLEKDAGKH 707
FRS R LG E D K + Q + ++++ KI+++GWSYGG+ +LKT+E D G
Sbjct: 743 FRSWAREKLGYWEPRDITEVTKKFIQRNSQHIDESKIAIWGWSYGGFTSLKTVELDNGDT 802
Query: 708 FKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEGY-DKCKVHNATAFATVPRFLLMHGTA 766
FKY ++VAPVT+W LYDSVYTERYM+ P +N EGY + + N +F ++ R ++HGT
Sbjct: 803 FKYAMAVAPVTNWTLYDSVYTERYMNQPSENHEGYFEVSTIQNFKSFESLKRLFIVHGTF 862
Query: 767 DDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNWIRHAY 823
DDNVH QN+ + +D LNL + NYD+H+FPDSDHSI+YHNA IVF K+ W+R A+
Sbjct: 863 DDNVHIQNTFRLVDQLNLLGLTNYDMHIFPDSDHSIRYHNAQRIVFQKLYYWLRDAF 919
>7297021 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 745
Score = 307 bits (787), Expect = 4e-83
Identities = 219/672 (32%), Positives = 335/672 (49%), Gaps = 54/672 (8%)
Query: 147 YDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYENDS-----FHKIDSEISI 201
++ NY SP+ +K+LIR + +RHS Y V++ ++ HK ++
Sbjct: 84 FELNNYVGATFSLSPDNTKILIRHNLTEKFRHSYIAQYDVFDIETNTTVQIHK-GEKLQY 142
Query: 202 AKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSE-LVFNGKPDWVYEEEVLEGDTA 260
WSP + YV N+++++ S+S E S IT+DG + +V+NG PDWVYEEEVL +A
Sbjct: 143 CGWSPLRDRLAYVYLNNVFIHFSESLEIS--ITDDGVDGVVYNGVPDWVYEEEVLSSGSA 200
Query: 261 LWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPINKLNI 320
+WWS G LA N+T VE F + T YP ++KYPKSGS NP+ L +
Sbjct: 201 IWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLKYPKSGSKNPVVSLRV 260
Query: 321 YDLSADK------VSQIDSTSDDSLITEVTWVGNHEIIAKVSDRSSDILTVIMVDAADGS 374
YD+S + V+ +D DD ++ V W + ++ +R + LT I + +G
Sbjct: 261 YDVSDNDPTMHTIVAPVDIVGDDHILQSVVWSNSTHLLITWMNRRQN-LTSIQSCSYEGD 319
Query: 375 RSEVSRIEESDGGWWEITHKTTFVPKDKSRSRS-YNGYIDLVPVDGYNHLVYFTTNVTTE 433
EV R+EE GW +I+ PK S +S GY +D ++ + + ++ T
Sbjct: 320 CVEVKRLEEPQ-GWVDIS-----TPKCLSTGKSCIFGYF----IDNWHQV--WNLDLETG 367
Query: 434 IPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDERL 493
+ S + G + V+ +DE + +Y+ AT + + N E D
Sbjct: 368 LNS-WQSRGNFTVL-SVYGYDEARDKLYYQATLPGDPSVYHVFSNDECLSCGQIDADGAA 425
Query: 494 NGYYSASFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNIRGNIIGKTLYYLEKNEKLH 553
S +FS + L+ GP+ Y +I + + T + N T Y + EKL
Sbjct: 426 CRSASGTFSKSFSYYTLSCTGPNPSYTRIFEASTKTLQVDWEPN----TAYRKQIEEKLR 481
Query: 554 NSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAYGGPNSQ 613
P+ F +TL G + LP +F + K YP+ Y GPNS
Sbjct: 482 --------PSYRFMNVTLADGSIGYAKLA-----LPPNFVETKK--YPLIVVVYQGPNSV 526
Query: 614 QVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQILAAKLY 673
+V F +G+ + + D I +DGRGTG KGK+ V +LGD E DQ+ +
Sbjct: 527 RVTNGFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWM 586
Query: 674 GQN-SYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLYDSVYTERYM 732
QN ++V+ E+ ++GWSYGGY+T KT+EKD + F+ GVSVAPVT WL YD++YTERYM
Sbjct: 587 QQNLAFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYM 646
Query: 733 HTP--QKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLNLNNIENY 790
P N + Y++ V FLL+HG+ DDNVH+Q+SL LL +I+ +
Sbjct: 647 GLPTDDDNLKKYNESSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQ-F 705
Query: 791 DVHVFPDSDHSI 802
+ + D +H I
Sbjct: 706 EEQTYTDENHGI 717
>Hs18765694 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 766
Score = 296 bits (759), Expect = 7e-80
Identities = 229/782 (29%), Positives = 369/782 (46%), Gaps = 83/782 (10%)
Query: 75 DYTKDGLLKVSFANVRNRTFQPEVKPLQWISTPDSHKNDKGLYVTFENDTYSVRSVLDES 134
D T D + + T++ ++ L+WIS + + + F N Y SV E+
Sbjct: 34 DATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVF-NAEYGNSSVFLEN 92
Query: 135 YSKTLFEGTSFTYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYEND---- 190
T+D ++++ SP+ +L+ K WRHS +Y +Y+ +
Sbjct: 93 S----------TFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQL 142
Query: 191 -SFHKIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSE-LVFNGKPDW 248
+ +I + WSP + YV NDIY+ + + S RIT G E +++NG DW
Sbjct: 143 ITEERIPNNTQWVTWSPVGHKLAYVWNNDIYV-KIEPNLPSYRITWTGKEDIIYNGITDW 201
Query: 249 VYEEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPK 308
VYEEEV +ALWWSP G +LA+ + N+T V ++ E+ YP+ ++ YPK
Sbjct: 202 VYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQ---YPKTVRVPYPK 258
Query: 309 SGSSNPINKLNIYDLSADKVSQIDSTSD------------DSLITEVTWVGNHEIIAKVS 356
+G+ NP K + ++ D +S + + + D + +VTW I +
Sbjct: 259 AGAVNPTVKFFV--VNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWL 316
Query: 357 DRSSDILTVIMVDAADGS---RSEVSR--IEESDGGWWEITHKTTFVPKDKSRSRSYNGY 411
R + + + D + S V+R IE S GW F P + + N +
Sbjct: 317 RRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGW-----VGRFRPSEPHFTLDGNSF 371
Query: 412 IDLVP-VDGYNHLVYFTTNVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSST 470
++ +GY H+ YF + + +T G WEV+ G A ++ +Y+I+ +
Sbjct: 372 YKIISNEEGYRHICYFQID---KKDCTFITKGTWEVI-GIEALTSDY--LYYISNEYKGM 425
Query: 471 E--RHLYYVNLERPQKVYAVTDERLNG----YYSASFSAGARFLLLNYLGPDVPYQKIID 524
R+LY + L KV ++ E LN YYS SFS A++ L GP +P +
Sbjct: 426 PGGRNLYKIQLSDYTKVTCLSCE-LNPERCQYYSVSFSKEAKYYQLRCSGPGLP---LYT 481
Query: 525 LKSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNS 584
L S DK +R LE N L L+ +P++ + L + + +I
Sbjct: 482 LHSSVNDKGLR---------VLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMI--- 529
Query: 585 YEILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTG 644
LP FD S K YP+ Y GP SQ+ F + + +AS + IV DGRG+G
Sbjct: 530 ---LPPHFDKSKK--YPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSG 584
Query: 645 FKGKEFRSIVRGNLGDVESTDQILAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDA 704
++G + + LG E DQI AA+ + + +V+ ++I+++GWSYGGY+T L +
Sbjct: 585 YQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGS 644
Query: 705 GKHFKYGVSVAPVTDWLLYDSVYTERYM--HTPQKNPEGYDKCKVHNATAFATVPRFLLM 762
G FK G++VAPV+ W YDSVYTERYM TP+ N + Y V + +LL+
Sbjct: 645 GV-FKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLI 703
Query: 763 HGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNWIRHA 822
HGTADDNVHFQ S + L ++ + + D DH I A+ ++ + ++I+
Sbjct: 704 HGTADDNVHFQQSAQISKALVDVGVD-FQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQC 762
Query: 823 YN 824
++
Sbjct: 763 FS 764
>Hs16933540 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 760
Score = 293 bits (749), Expect = 1e-78
Identities = 226/766 (29%), Positives = 363/766 (46%), Gaps = 78/766 (10%)
Query: 70 PNKQIDYTKDGLLKVSFANVRNRTFQPEVKPLQWISTPDSHKNDKGLYVTFENDTYSVRS 129
P++ + ++ + ++ ++ N TF + WIS + L+ + +N+
Sbjct: 28 PSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWIS------GQEYLHQSADNNIVLYNI 81
Query: 130 VLDESYSKTLFEGTSFTYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYE- 188
+SY+ L T + ++ NY + SP+ V + S+ K WR+S TY++Y+
Sbjct: 82 ETGQSYT-ILSNRTMKSVNASNYGL-----SPDRQFVYLESDYSKLWRYSYTATYYIYDL 135
Query: 189 -NDSF---HKIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSELVFNG 244
N F +++ I WSP + YV N+IYL + N +FNG
Sbjct: 136 SNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNG 195
Query: 245 KPDWVYEEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKI 304
PDWVYEEE+L ALWWSP G +LA+ + N+T + Y+ E YP I
Sbjct: 196 IPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQ-----YPRTINI 250
Query: 305 KYPKSGSSNPINKLNIYDLSADKVSQIDST-------SDDSLITEVTWVGNHEIIAKVSD 357
YPK+G+ NP+ ++ I D + S D + +TWV + + +
Sbjct: 251 PYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLK 310
Query: 358 RSSDILTVIMVDAADGSRS-----EVSRIEESDGGWWEITHKTTFVPKDKSRSRSYNGYI 412
R ++ + + D + ++ IEES GW +T P + SY Y
Sbjct: 311 RVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVST--PVFSYDAISY--YK 366
Query: 413 DLVPVDGYNHLVYFTTNVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATK--KSST 470
DGY H+ Y V I +TSG+WE ++ F +++++ + + +
Sbjct: 367 IFSDKDGYKHIHYIKDTVENAIQ---ITSGKWEAIN---IFRVTQDSLFYSSNEFEEYPG 420
Query: 471 ERHLYYVNL-ERPQKVYAVT----DERLNGYYSASFSAGARFLLLNYLGPDVPYQKIIDL 525
R++Y +++ P VT ER YY+ASFS A++ L GP +P + D
Sbjct: 421 RRNIYRISIGSYPPSKKCVTCHLRKERCQ-YYTASFSDYAKYYALVCYGPGIPISTLHDG 479
Query: 526 KSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSY 585
++D + K LE+N++L N+LK +P ++L + D I Y
Sbjct: 480 RTDQEIK------------ILEENKELENALKNIQLPKEEIKKLEV-------DEITLWY 520
Query: 586 E-ILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTG 644
+ ILP FD S K YP+ YGGP SQ V F + + +AS+ ++ +VDGRGT
Sbjct: 521 KMILPPQFDRSKK--YPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA 578
Query: 645 FKGKEFRSIVRGNLGDVESTDQILAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDA 704
F+G + V LG E DQI A + + + ++++++I+++GWSYGGY++ L
Sbjct: 579 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT 638
Query: 705 GKHFKYGVSVAPVTDWLLYDSVYTERYMHTPQK--NPEGYDKCKVHNATAFATVPRFLLM 762
G FK G++VAPV+ W Y SVYTER+M P K N E Y V + +LL+
Sbjct: 639 GL-FKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLI 697
Query: 763 HGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNAN 808
HGTADDNVHFQNS + L +N ++ + D +H + + N
Sbjct: 698 HGTADDNVHFQNSAQIAKAL-VNAQVDFQAMWYSDQNHGLSGLSTN 742
>7294364 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 802
Score = 275 bits (703), Expect = 2e-73
Identities = 198/686 (28%), Positives = 327/686 (46%), Gaps = 62/686 (9%)
Query: 148 DSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYENDSFHKIDSEI-------S 200
D+++Y + A E +L+ +K +R+S Y +Y ++ I I S
Sbjct: 119 DAQHYVLYEKSADGEF--LLLAKNYKKNFRYSFLAEYDLYNLNTKEFIQLTIQNEQHYLS 176
Query: 201 IAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSELVFNGKPDWVYEEEVLEGDTA 260
+ +WSP +V ++Y Y + +T+D + NG PDWVYEEEV + A
Sbjct: 177 MVQWSPVGNALVINYDRNLY-YKESALAQEIALTSDEQAGILNGIPDWVYEEEVFSSNVA 235
Query: 261 LWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPINKLNI 320
W++P+G LAF K +++S PY+ YP + I YPK+GSSNP +L +
Sbjct: 236 TWFNPSGTQLAFIKFDDSSTHLINFPYYGDAGDLRYQYPLHQVIAYPKAGSSNPRVELVM 295
Query: 321 YDLS-----ADKVSQID-----STSDDSLITEVTWVGNHEIIAKVSDRSSDILTVIMVDA 370
DL D V+ + +T D ++T V+WV + +++ +R + V+ D
Sbjct: 296 VDLKRAVAGGDFVTVMPVPSALNTETDYIVTVVSWVDDDNVLSIWMNRIQNAAYVVTFD- 354
Query: 371 ADGSRSEVSRIEESDGGWWEITHKTTFVPKDKSRSRSYNGYIDLVPVDGYNHLVYFTTNV 430
G +V ES GW ++ + ++R+ S ++ +P + Y H+ ++ V
Sbjct: 355 --GLNRKVIYSAESKTGWVDL-----YTAPFRNRNGSRLAFV--LPHNNYKHVQLLSSTV 405
Query: 431 TTEIPSVV--LTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTER-HLYYVNLERPQKVYA 487
+ P + LT G++ VVD +D + + +++ A + E+ HLY + Q
Sbjct: 406 ASSEPQALEPLTEGKY-VVDSILHWDGKNDIIFYTANTEDHPEQLHLYAIRALAKQSPKC 464
Query: 488 VTDERLNG------YYSASFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNIRGNIIGK 541
+T + Y+SA+F+ +++ LGP +P I + K + +I K
Sbjct: 465 LTCNLIKSGDVQQTYFSATFNDN-NHIVITSLGPGIPTTHIYEWKYENSQV-----VISK 518
Query: 542 TLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYP 601
L + E NE L LK A+P+ + LT+ D ++ LP + D S YP
Sbjct: 519 VLDW-ETNESLRAKLKGVALPSH--KILTVDIDGGFQAKVLLQ---LPPNLDTSGATKYP 572
Query: 602 VFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDV 661
+ YGGP+S V + + + ++S I +DGRG+G +G+ + LG V
Sbjct: 573 MLVDVYGGPDSYSVTNKWMVDWGTYLSSNQSVIYAKIDGRGSGLRGESLLHAIYLKLGTV 632
Query: 662 ESTDQI-LAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDW 720
E +DQI + KL +Y++ + + ++GWSYGGY L D K FK S+APVTDW
Sbjct: 633 EISDQINVTQKLSTLFNYIDPDHVGIWGWSYGGYAAAMALANDEAKVFKCAASIAPVTDW 692
Query: 721 LLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLD 780
YDS+YTERYM P N GY ++ ++LL+HGT DDNVH+Q +
Sbjct: 693 AYYDSIYTERYMGLPNTNELGYANSRLSTMAVKLRGKKYLLVHGTLDDNVHYQQA----- 747
Query: 781 LLNLNNIENYDVHV----FPDSDHSI 802
++ N+E D+ + D DH +
Sbjct: 748 MILAKNLERQDILFKQISYADEDHGL 773
>Hs22041021 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 746
Score = 273 bits (697), Expect = 1e-72
Identities = 217/771 (28%), Positives = 359/771 (46%), Gaps = 90/771 (11%)
Query: 75 DYTKDGLLKVSFANVRNRTFQPEVKPLQWISTPDS-HKNDKGLYVTFENDTYSVRSVLDE 133
+ T ++S ++ + F +WI+ D +K++ G + ++ ++
Sbjct: 10 ELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENG---------HVIKLNIET 60
Query: 134 SYSKTLFEGTSF-TYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVY----- 187
+ + L E T+F T+ + ++V SP+L VL+ + ++ + +S +Y +Y
Sbjct: 61 NATTLLLENTTFVTFKASRHSV-----SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTR 115
Query: 188 ---ENDSFHKIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSE-LVFN 243
E + DS + A W + ++Y+ N+IY Y D +S R+T+ G E ++FN
Sbjct: 116 EVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIY-YQPDIKSSSLRLTSSGKEEIIFN 174
Query: 244 GKPDWVYEEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRK 303
G DW+YEEE+L A WWSP G+ LAF IN++ V IP F T + YP+ ++
Sbjct: 175 GIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRF-----TGALYPKGKQ 229
Query: 304 IKYPKSGSSNPINKLNIYDL-----SADKVSQIDSTSDDSLITEVTWVGNHEIIAKVSDR 358
YPK+G NP KL + +L + + + S + IT V WV N + + + +R
Sbjct: 230 YPYPKAGQVNPTIKLYVVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNR 289
Query: 359 SSDILTVIMVDAADGSRSEVSRIEESDGGWWEITHKTTFVPKDKSRSRSYNGYIDLVPV- 417
+ +I + + + G+ S+ + E + W ++ +D S+ + VPV
Sbjct: 290 AQNISILTVCETTTGACSK--KYEMTSDTWLSQQNEEPVFSRDGSK------FFMTVPVK 341
Query: 418 ----DGYNHLVYFTTNVTTEIPSV-VLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTER 472
++H+ F +E +V LTSG WEV+ A+DE +YF++T+ S R
Sbjct: 342 QGGRGEFHHVAMFLIQSKSEQITVRHLTSGNWEVIK-ILAYDETTQKIYFLSTESSPRGR 400
Query: 473 HLYYVNLE---RPQKVYAVTDERLNGYYSASFSAGARFLLLNYLGPDVPYQKIIDLKSDT 529
LY + E Q + + Y+ ASFS + LL GP VP + +
Sbjct: 401 QLYSASTEGLLNRQCISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPA 460
Query: 530 KDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEI-- 587
K + LE N L ++ + I GK + + ++ YE+
Sbjct: 461 K------------YFILESNSMLKEAILKKKI----------GKPEI-KILHIDDYELPL 497
Query: 588 ---LPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTG 644
LP DF +N Y + P Q V F I ++ V+ + IV DGRG+G
Sbjct: 498 QLSLPKDFMD--RNQYALLLIMDEEPGGQLVTDKFHIDWDSVLIDMDNVIVARFDGRGSG 555
Query: 645 FKGKEFRSIVRGNLGDVESTDQILAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDA 704
F+G + + LG VE DQI A K + Y++ +++S+FG YGGY+ L+ D
Sbjct: 556 FQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDE 615
Query: 705 GKHFKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMHG 764
K FK G VAP+TD LY S ++ERY+ P K Y V + L++HG
Sbjct: 616 -KLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASVLHNVHGLKEENILIIHG 674
Query: 765 TADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSI----QYHNANVIV 811
TAD VHFQ+S + + L + NY + V+PD H++ +YH + I+
Sbjct: 675 TADTKVHFQHSAELIKHLIKAGV-NYTMQVYPDEGHNVSEKSKYHLYSTIL 724
>Hs18765698 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 865
Score = 267 bits (682), Expect = 6e-71
Identities = 189/685 (27%), Positives = 327/685 (47%), Gaps = 63/685 (9%)
Query: 160 SPELSKVLIRSETEKGWRHSTFGTYFVYE---NDSFHKIDSEISIAK-----WSPNSRDI 211
SP+ L E ++HS G Y + + D E+S AK W P + +
Sbjct: 195 SPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQL 254
Query: 212 VYVKGNDIYLYSSDSHETSKRITNDGSE-LVFNGKPDWVYEEEVLEGDTALWWSPTGDYL 270
+++ N+IY Y + + + R+ + G E +++NG DW+YEEE+L+ A WWSP G L
Sbjct: 255 IFIFENNIY-YCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRL 313
Query: 271 AFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPINKLNIYDLSA----- 325
A+ IN++ V +P + T S YP ++ YPK+GS NP L++ L+
Sbjct: 314 AYAAINDSRVPIMELPTY-----TGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDL 368
Query: 326 DKVSQIDSTSDDSLITEVTWVGNHEIIAKVSDRSSDILTVIMVDAADGSRSEVSRIEESD 385
+ + D + IT V W + ++ +R+ ++ + + DA G ++ + E+
Sbjct: 369 EMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTK--KHEDES 426
Query: 386 GGWWEITHKTTFVPKDKSRSRSYNGYIDLVPVDGYNHLVYFTTNVTTEIPS----VVLTS 441
W H+ P R + +I +P G + T + + S +TS
Sbjct: 427 EAW---LHRQNEEPVFSKDGRKFF-FIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS 482
Query: 442 GEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDERLNG--YYSA 499
G+W+V A+DE+ N +YF++T+ R LY N ++ + + Y+SA
Sbjct: 483 GDWDVTK-ILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA 541
Query: 500 SFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRY 559
SFS F LL GP VP + +T DK K ++ LE NE + ++
Sbjct: 542 SFSHSMDFFLLKCEGPGVPMVTV----HNTTDK--------KKMFDLETNEHVKKAINDR 589
Query: 560 AIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSL---KNHYPVFFFAYGGPNSQQVA 616
+P +R DI ++ Y + P+ HYP+ G P SQ VA
Sbjct: 590 QMPKVEYR-----------DIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVA 638
Query: 617 QTFGIGFNQVIASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQILAAKLYGQN 676
+ F + + V+ S A+VV DGRG+GF+G + VR LG +E DQ+ A + +
Sbjct: 639 EKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKE 698
Query: 677 SYVNKEKISLFGWSYGGYLT---LKTLEKDAGKHFKYGVSVAPVTDWLLYDSVYTERYMH 733
Y+++ ++++FG YGGYL+ L ++ G+ F G +++P+TD+ LY S ++ERY+
Sbjct: 699 QYIDRTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLG 758
Query: 734 TPQKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVH 793
+ Y+ KV + + +FL++H TAD+ +HFQ++ + + L + NY +
Sbjct: 759 LHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQL-IRGKANYSLQ 817
Query: 794 VFPDSDHSIQYHNANVIVFNKILNW 818
++PD H + ++ I+N+
Sbjct: 818 IYPDESHYFTSSSLKQHLYRSIINF 842
>Hs18765696 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 803
Score = 267 bits (682), Expect = 6e-71
Identities = 189/685 (27%), Positives = 327/685 (47%), Gaps = 63/685 (9%)
Query: 160 SPELSKVLIRSETEKGWRHSTFGTYFVYE---NDSFHKIDSEISIAK-----WSPNSRDI 211
SP+ L E ++HS G Y + + D E+S AK W P + +
Sbjct: 133 SPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQL 192
Query: 212 VYVKGNDIYLYSSDSHETSKRITNDGSE-LVFNGKPDWVYEEEVLEGDTALWWSPTGDYL 270
+++ N+IY Y + + + R+ + G E +++NG DW+YEEE+L+ A WWSP G L
Sbjct: 193 IFIFENNIY-YCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRL 251
Query: 271 AFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPINKLNIYDLSA----- 325
A+ IN++ V +P + T S YP ++ YPK+GS NP L++ L+
Sbjct: 252 AYAAINDSRVPIMELPTY-----TGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDL 306
Query: 326 DKVSQIDSTSDDSLITEVTWVGNHEIIAKVSDRSSDILTVIMVDAADGSRSEVSRIEESD 385
+ + D + IT V W + ++ +R+ ++ + + DA G ++ + E+
Sbjct: 307 EMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTK--KHEDES 364
Query: 386 GGWWEITHKTTFVPKDKSRSRSYNGYIDLVPVDGYNHLVYFTTNVTTEIPS----VVLTS 441
W H+ P R + +I +P G + T + + S +TS
Sbjct: 365 EAW---LHRQNEEPVFSKDGRKFF-FIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS 420
Query: 442 GEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDERLNG--YYSA 499
G+W+V A+DE+ N +YF++T+ R LY N ++ + + Y+SA
Sbjct: 421 GDWDVTK-ILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA 479
Query: 500 SFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRY 559
SFS F LL GP VP + +T DK K ++ LE NE + ++
Sbjct: 480 SFSHSMDFFLLKCEGPGVPMVTV----HNTTDK--------KKMFDLETNEHVKKAINDR 527
Query: 560 AIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSL---KNHYPVFFFAYGGPNSQQVA 616
+P +R DI ++ Y + P+ HYP+ G P SQ VA
Sbjct: 528 QMPKVEYR-----------DIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVA 576
Query: 617 QTFGIGFNQVIASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQILAAKLYGQN 676
+ F + + V+ S A+VV DGRG+GF+G + VR LG +E DQ+ A + +
Sbjct: 577 EKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKE 636
Query: 677 SYVNKEKISLFGWSYGGYLT---LKTLEKDAGKHFKYGVSVAPVTDWLLYDSVYTERYMH 733
Y+++ ++++FG YGGYL+ L ++ G+ F G +++P+TD+ LY S ++ERY+
Sbjct: 637 QYIDRTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLG 696
Query: 734 TPQKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVH 793
+ Y+ KV + + +FL++H TAD+ +HFQ++ + + L + NY +
Sbjct: 697 LHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQL-IRGKANYSLQ 755
Query: 794 VFPDSDHSIQYHNANVIVFNKILNW 818
++PD H + ++ I+N+
Sbjct: 756 IYPDESHYFTSSSLKQHLYRSIINF 780
>CE21195 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 779
Score = 219 bits (557), Expect = 2e-56
Identities = 179/687 (26%), Positives = 309/687 (44%), Gaps = 82/687 (11%)
Query: 177 RHSTFGTYFVYEND------SFHKIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETS 230
++ TF V N+ K +S I KW+ D V+V+ N IY SS E
Sbjct: 137 QNETFHLKIVNNNERITYDIGLRKEESVIQAFKWNGKFNDFVFVESNKIYYQSSPEEEGL 196
Query: 231 KRITNDGSELVFNGKPDWVYEEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQ 290
R++N G V +G DW+YEEE+ A+WWS GD LA+ + + + +
Sbjct: 197 TRVSNGGEHTV-DGLFDWIYEEEIFGRKDAMWWSTKGDQLAYASYDNHLTKNVSLKTY-- 253
Query: 291 ENQTNSAYPELRKIKYPKSGSSN-PINKLNIYDLSADKVSQIDSTSDDSL----ITEVTW 345
YP YPK+ + P L+I++ ++ Q+D DSL + V W
Sbjct: 254 --HRLEPYPIDTNFHYPKTFAKVLPTYTLSIWNKKTEQSRQLDVQLKDSLSYHYLLAVKW 311
Query: 346 V---GNHEIIAKVSDRSSDILTVIMVDAADGSRSEVSRIEESDGGWWEITHKTTFVPKDK 402
+ G ++++ ++R + + + + D W + F + K
Sbjct: 312 LEINGTEQLVSVWTNRYQNEVALTICD------------------WDTAICRLEF--EYK 351
Query: 403 SRSRSYNGYIDLVPVDGYNHLVYFTT------NVTTEIPSVVLTSGEWEV---------- 446
S+ + + D + + ++F N ++ S+ L+ G+
Sbjct: 352 YASKRWVTHDDFHSITSFEDTLFFLLPHDKRDNAFQQVASLRLSHGQLRTPKFLNLGEYD 411
Query: 447 VDGPAAFDEEFNNVYFIATKKSSTERHLYYVNL--ERPQKVYAVTDERLNGYYS-ASFSA 503
V ++E ++F A + R L+ +L E Y ++ N ++ A
Sbjct: 412 VTSINGINKETRTIFFHAAAPKPSHRSLFSYSLADESRNSAYCISCSIKNCTWAQAQMDD 471
Query: 504 GARFLLLNYLGPDVPYQKIIDL-KSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIP 562
+ +++ GP P+ I++L + D+ K N++ Y N ++ +P
Sbjct: 472 QMKTAIVSCKGPAAPHTAIVNLTRMDSDKKTEHANLLYDKTY--------QNRVEEAGLP 523
Query: 563 ARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIG 622
I + + D + + +I D ++ P+ YGGPN Q + IG
Sbjct: 524 VIIKETIKISDDFDALIKLSIPKDIYNRDKHQAI----PLIVHVYGGPNDQNTKEATQIG 579
Query: 623 FNQVIASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQILAAK--LYGQNSYVN 680
+V+AS A ++ +DGRG+G +G ++RS + G LG VE DQI A K L ++
Sbjct: 580 IEEVVASASQAAILRIDGRGSGGRGWKYRSAIYGQLGTVEVEDQIKAIKVVLRLYRHLLD 639
Query: 681 KEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLYDSVYTERYM-HTPQKNP 739
++++FGWSYGG++TL + + + FK VSVAPVT++ YD+ YTERYM P ++
Sbjct: 640 ARRVAVFGWSYGGFMTLSMVNEAPEQFFKCAVSVAPVTNFAYYDATYTERYMGDAPLESY 699
Query: 740 EGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSD 799
K K+ N + R LLMHG DDNVHFQNS +D L ++ +D+ V+P+
Sbjct: 700 SDVTK-KLDNFKS----TRLLLMHGLLDDNVHFQNSAILIDELQNRGVD-FDLMVYPNQA 753
Query: 800 HSIQYHNANVIVFNKILNWIRHAYNGD 826
HS+ ++V+ K+ +++R + D
Sbjct: 754 HSLSSRTSHVV--GKMTHFLRQCFYTD 778
>CE21196 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 799
Score = 218 bits (556), Expect = 2e-56
Identities = 175/664 (26%), Positives = 302/664 (45%), Gaps = 76/664 (11%)
Query: 194 KIDSEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSELVFNGKPDWVYEEE 253
K +S I KW+ D V+V+ N IY SS E R++N G V +G DW+YEEE
Sbjct: 180 KEESVIQAFKWNGKFNDFVFVESNKIYYQSSPEEEGLTRVSNGGEHTV-DGLFDWIYEEE 238
Query: 254 VLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSN 313
+ A+WWS GD LA+ + + + + YP YPK+ +
Sbjct: 239 IFGRKDAMWWSTKGDQLAYASYDNHLTKNVSLKTY----HRLEPYPIDTNFHYPKTFAKV 294
Query: 314 -PINKLNIYDLSADKVSQIDSTSDDSL----ITEVTWV---GNHEIIAKVSDRSSDILTV 365
P L+I++ ++ Q+D DSL + V W+ G ++++ ++R + + +
Sbjct: 295 LPTYTLSIWNKKTEQSRQLDVQLKDSLSYHYLLAVKWLEINGTEQLVSVWTNRYQNEVAL 354
Query: 366 IMVDAADGSRSEVSRIEESDGGWWEITHKTTFVPKDKSRSRSYNGYIDLVPVDGYNHLVY 425
+ D W + F + K S+ + + D + + ++
Sbjct: 355 TICD------------------WDTAICRLEF--EYKYASKRWVTHDDFHSITSFEDTLF 394
Query: 426 FTT------NVTTEIPSVVLTSGEWEV----------VDGPAAFDEEFNNVYFIATKKSS 469
F N ++ S+ L+ G+ V ++E ++F A
Sbjct: 395 FLLPHDKRDNAFQQVASLRLSHGQLRTPKFLNLGEYDVTSINGINKETRTIFFHAAAPKP 454
Query: 470 TERHLYYVNL--ERPQKVYAVTDERLNGYYS-ASFSAGARFLLLNYLGPDVPYQKIIDL- 525
+ R L+ +L E Y ++ N ++ A + +++ GP P+ I++L
Sbjct: 455 SHRSLFSYSLADESRNSAYCISCSIKNCTWAQAQMDDQMKTAIVSCKGPAAPHTAIVNLT 514
Query: 526 KSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSY 585
+ D+ K N++ Y N ++ +P I + + D + +
Sbjct: 515 RMDSDKKTEHANLLYDKTY--------QNRVEEAGLPVIIKETIKISDDFDALIKLSIPK 566
Query: 586 EILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGF 645
+I D ++ P+ YGGPN Q + IG +V+AS A ++ +DGRG+G
Sbjct: 567 DIYNRDKHQAI----PLIVHVYGGPNDQNTKEATQIGIEEVVASASQAAILRIDGRGSGG 622
Query: 646 KGKEFRSIVRGNLGDVESTDQILAAK--LYGQNSYVNKEKISLFGWSYGGYLTLKTLEKD 703
+G ++RS + G LG VE DQI A K L ++ ++++FGWSYGG++TL + +
Sbjct: 623 RGWKYRSAIYGQLGTVEVEDQIKAIKVVLRLYRHLLDARRVAVFGWSYGGFMTLSMVNEA 682
Query: 704 AGKHFKYGVSVAPVTDWLLYDSVYTERYM-HTPQKNPEGYDKCKVHNATAFATVPRFLLM 762
+ FK VSVAPVT++ YD+ YTERYM P ++ K K+ N + R LLM
Sbjct: 683 PEQFFKCAVSVAPVTNFAYYDATYTERYMGDAPLESYSDVTK-KLDNFKS----TRLLLM 737
Query: 763 HGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNWIRHA 822
HG DDNVHFQNS +D L ++ +D+ V+P+ HS+ ++V+ K+ +++R
Sbjct: 738 HGLLDDNVHFQNSAILIDELQNRGVD-FDLMVYPNQAHSLSSRTSHVV--GKMTHFLRQC 794
Query: 823 YNGD 826
+ D
Sbjct: 795 FYTD 798
>SPAC14C4.15c [O] KOG2100 Dipeptidyl aminopeptidase
Length = 743
Score = 211 bits (538), Expect = 3e-54
Identities = 196/785 (24%), Positives = 344/785 (42%), Gaps = 111/785 (14%)
Query: 94 FQPEVKPLQWISTPDSHKNDKGLYVTFENDTYSVRSVLDES--YSKTLFEG-TSFTYDSK 150
F P + ++WI++ + G + ++ T+S+ + Y + TSF K
Sbjct: 11 FLPYHQDIEWITSTE------GTVLYYDQSTFSLSLFYPDGKEYGSNVDSLITSFVLTCK 64
Query: 151 NYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYENDSFH------KIDSEISIAKW 204
N + S ++ + ++ WRHS + ++ E + +I +A+W
Sbjct: 65 N--LHRKRYSSDMEYIAFSCSKDRRWRHSYYEDVYLVERATGRIEHLASDQSKKIVVAEW 122
Query: 205 SPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSEL--VFNGKPDWVYEEEVLEGDTALW 262
SP +VY G++++++ S S E IT D S+L +FNG DWVYEEE+L+ A+W
Sbjct: 123 SPIGHKLVYGLGSNLFIWESFS-EPPVCIT-DQSDLDGLFNGNSDWVYEEEILQSSKAVW 180
Query: 263 WSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPINKL--NI 320
WSP G+ L++ I+++ V +P+ +++ Y P KL N
Sbjct: 181 WSPDGNCLSYLSIDDSKVPVHVLPFEQLDSKVEDQNRVNNFFHYSTPKDPIPFVKLFVNC 240
Query: 321 YDLSADKVSQIDST----SDDSLITEVTWVGN------------HEIIAKVSDRSSDILT 364
+ S + + ++DS+ + IT+V W GN +E + + D SS T
Sbjct: 241 FTDSGESI-EVDSSFPLSTQHRYITDVAWAGNEKLMFVEVLRGNYERVTSLFDLSSRKTT 299
Query: 365 VIMVDAADGSRSEVSRIE------ESDGGWWEITHKTTFVPKDKSRSRSYNGYIDLVPVD 418
+ + ++ + S + ES G E + F+ +K R Y + VP+
Sbjct: 300 IENTEVSEHPLALTSSLHLKYLSFESLGNLKERYVRQYFL-SNKKRIAIYE-LDNPVPI- 356
Query: 419 GYNHLVYFTTNVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVN 478
Y T + + + L + N +YF A S +Y +
Sbjct: 357 ------YLTPVNISFLSDLYLIN----------------NTLYFTAISSGSPFSRVYRL- 393
Query: 479 LERPQKVYAVTDERLNGYYSASFSAGARFLLLNYLGPDVPYQKIIDLKSD---TKDKNIR 535
+ + + + +G + S +LL+NYLGP++P Q I + D T + + +
Sbjct: 394 CTKSLILSEINIQIGSGLFGIKVSNDQNYLLVNYLGPEIPKQFIYSIHEDKVSTSNDHSK 453
Query: 536 GNI--------IGKTLYYL----EKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVN 583
N+ +GK L E NE+L + +++A P+ F+ + + +I
Sbjct: 454 NNLPSDSSSTSLGKVKLELCNSLETNEELIITKEKFAFPSVFFKVIKV------KNITAY 507
Query: 584 SYEILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGT 643
EI P +F+P + YP F YG P S V + + N+++AS + +V+ VD
Sbjct: 508 IQEIRPPNFNP--RKRYPTVFHLYGAPQSALVTGKYEMDINELMASVYNFLVIKVDIVDI 565
Query: 644 GFKGKEFRSIVRGNLGDVESTDQILAA-----KLYGQNSYVNKEKISLFGWSYGGYLTLK 698
S V G +S + I+ + + Y Y+++ ++ ++GWS+GGYLTLK
Sbjct: 566 --------SDVSGQHLFSDSHELIIKSWIELLRSYVDTPYIDRHRVGIWGWSFGGYLTLK 617
Query: 699 TLEKDAGKHFKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEG-YDKCKVHNATAFATVP 757
LE K G VAPVTDW YD+ Y+E + K YDK VH + F +
Sbjct: 618 ILEN--ADFIKTGAVVAPVTDWRYYDAYYSENLLGAYSKQTTAIYDKTAVHYSENFRKLC 675
Query: 758 RFLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILN 817
L++HGT+DDNVH +N+++ + + NY + P+++H + K+
Sbjct: 676 GLLVLHGTSDDNVHIENTMQLTKAMVEKGVYNYYPFIVPNANHEFSDPTDYTFLREKLSG 735
Query: 818 WIRHA 822
HA
Sbjct: 736 HFHHA 740
>7301225 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 1102
Score = 211 bits (536), Expect = 5e-54
Identities = 189/697 (27%), Positives = 309/697 (44%), Gaps = 109/697 (15%)
Query: 207 NSRDIVYVKGNDIYL-YSSDSHETSKRITNDG-----SELVFNGKPDWVYEEEVLEGDTA 260
NS I Y+ D+++ ++ HE T+ G + + G P +V +EE
Sbjct: 432 NSDMIAYISDCDLFVTHTLSGHEKRLTYTSTGRHSYVDDALSAGVPSYVMQEEFSRYQ-G 490
Query: 261 LWWSP---TGDY-LAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPIN 316
WW P G Y + + +++E+ V + P + + + + + ++P++GS N +
Sbjct: 491 FWWQPHSNDGIYRIVYEEVDESEVSVYTFP------SSTAMHGRVDEYRFPRTGSPNAKS 544
Query: 317 KLNIYDLSADKVSQIDSTSDDSL-------------ITEVTWVGNHEII-AKVSDRSSDI 362
KL + ++ Q+ + L I V W + + + + DR
Sbjct: 545 KLKLVQFVLNEALQVSEIAIKDLPYSLLAVFSWLEYIVRVGWTPDAKYVWVQGLDRKQQR 604
Query: 363 LTVIMV---DAADGSRSEVSRIEESDGGW-WEITHKTTFVPKD---KSRSRSYNG----- 410
L VI++ + + S+VS +S G W + T P RS S+
Sbjct: 605 LDVILIPLDNFCESYSSQVSTPTDSIGDHSWRSLYSRTITPLQVIYTERSDSWINVHDML 664
Query: 411 -YIDLVPVD----------GYNHLVYFTTNVTTE-------------------------- 433
++DL G+ HL T ++
Sbjct: 665 HFLDLTETSVTFLWASEETGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFVDLSALQPR 724
Query: 434 -IPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDER 492
+ V LTSGEWEV+ D+ VYF+ + + E+HLY V+LERP+ + +T+
Sbjct: 725 ILNKVALTSGEWEVLARNLWVDKANKLVYFVGLRDTPLEKHLYVVSLERPEHIRLLTEP- 783
Query: 493 LNGY-YSASFSAGARFLLLNYLG-PDVPYQKIIDLKSDTKDKNIRGNIIGKTLYYLEKNE 550
GY Y F + +LL Y +P K++ + + + G I Y E +
Sbjct: 784 --GYSYLVEFDDQCKLMLLVYCNIQRLPSCKVMRVNQTCSNGGVNGIQISLVGYLHEGGK 841
Query: 551 KLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAYGGP 610
+ P Q S IV + P++F+ +K YP YGGP
Sbjct: 842 PEPQYCPQIFSP------------QLPSGDIVYAMVFKPHNFELGVK--YPTVLNVYGGP 887
Query: 611 NSQQVAQTFGIGFNQVIASQLDA---IVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQI 667
Q V TF G +Q+ L A V+ +D RG+ +GK F S +RG +G VE TDQ+
Sbjct: 888 EVQTVNNTFK-GKHQLRMHMLAAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQV 946
Query: 668 LAAK-LYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLYDSV 726
A + L Q Y++ +++++ GWSYGGYL+L L + K FK ++ APVT+W YD+
Sbjct: 947 DALRSLSDQLGYIDMDRVAIHGWSYGGYLSLMGLVQ-YPKIFKVAIAGAPVTNWEYYDTG 1005
Query: 727 YTERYMHTPQKNPEGYDKCKV-HNATAFATV-PRFLLMHGTADDNVHFQNSLKYLDLLNL 784
YTERYM PQ N GY V +F R LL+HG D+NVHF ++ + + LN
Sbjct: 1006 YTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALNK 1065
Query: 785 NNIENYDVHVFPDSDHSIQYHNANVIVFNKILNWIRH 821
N + Y+VH+FP+ HS++ +N K+L+++++
Sbjct: 1066 AN-KPYEVHLFPEERHSLRNLESNKNYETKLLSFLQN 1101
>CE05324 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 829
Score = 194 bits (492), Expect = 6e-49
Identities = 201/821 (24%), Positives = 352/821 (42%), Gaps = 85/821 (10%)
Query: 30 FLVTACLSLSTVLFSAYLFISIISSLKGSGTLNNGSGPRLPNKQIDYTKDGLLKVSFANV 89
F + C+ ++ ++F I + ++ LN+ +G + + LK F+++
Sbjct: 23 FARSCCVVFILIICVIFVFSVIFTFMQNPINLNSDNGFNQTSGNTSSLEATTLKPKFSSL 82
Query: 90 ----RNRTFQPEVKPLQW-ISTPDSHKNDKGLYVTFENDTYSVRSVLDESYSKTLFEGTS 144
R TF+ Q+ + D G +V ND +++R + K + G+S
Sbjct: 83 MTTTRRFTFEQLFSGKQFLVDYYDYIWLPDGSFVQM-NDDFTIRKQM-----KKIPLGSS 136
Query: 145 FTYDSKNYTVDAVVASPELSKVLIRSETEKGWRHSTFGTYFVYE-------NDSFHKIDS 197
N S + + + WRHS Y + + + +H
Sbjct: 137 VAEPFFNNGEYVKALSSNMKYAYGSKKVNELWRHSAEYLYHIVKINNKTVSTEQWHVGPE 196
Query: 198 EISIAK---WSPN--SRDIVYVKGNDIYLYSSDSHETSKRI--TNDGSELVFNGKPDWVY 250
E S+ + W+PN S D VYV ++Y Y D + I T GS G +W+Y
Sbjct: 197 ENSLIQAFYWNPNASSNDFVYVHNYNLY-YQKDPEKPDGAIQLTVGGSTFNRFGLANWLY 255
Query: 251 EEEVLEGDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSG 310
EEE+LE +A+WWSP+G Y+++ + ++ V +P + ++ +Y E ++ YPK+G
Sbjct: 256 EEEILEASSAVWWSPSGRYVSYLRFDDREVNRIFLPKYTDDD----SYVEYFELPYPKAG 311
Query: 311 -SSNPINKLNIYDLSADKV------SQIDSTSDDSLITEVTWVGNHEIIAKVSDRSSDIL 363
+N + I+D K+ +++ + + D + W+ + SD + L
Sbjct: 312 VQNNTLVTQYIWDSENHKIVETAPPNELSAANGDYYVLTNKWI---TMPRNGSDLGEERL 368
Query: 364 TVIMVDAADGSRSEVSRIEESD-----GGWWEITHKTTFV-PKD-KSRSRSYNGYIDLVP 416
+ + D + S E D + I ++ +V PKD + + G++ ++P
Sbjct: 369 VTVWANR-DQNHVYFSLCNEQDCVMALSFQFSIDNRQLWVSPKDVRGVFPTETGFLTVLP 427
Query: 417 V---DG--YNHLVYFTTNVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTE 471
DG YNH+ + + T + GE V + + + + F A E
Sbjct: 428 HKHDDGNIYNHVAHVELD-GTGTGKITKWIGENFDVILVLGYSSKIDALTFSAYGDGVGE 486
Query: 472 RHLYYVN----LERPQKVYAVTDERLNGYYSASFSA---GARFLLLNYLGPDVPYQKIID 524
Y V + + VTD+ + S SA G R ++ D ++D
Sbjct: 487 FSTYIVREAMYSNKKTTLQKVTDQFEDCKTLGSQSADPTGQRIVVQCEKPFDNTRLYLVD 546
Query: 525 LKSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNS 584
+ TK + G ++ + +P F +L L +G +++
Sbjct: 547 VVDTTKKIMLEGGT---------------KAVIPFDVPNMKFGKLKLPSGIDGHYMMLTP 591
Query: 585 YEILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTG 644
+L P+ YGGP+S+QV Q I SQ D +D RGTG
Sbjct: 592 ANLLDGA-------KIPLLLDIYGGPDSKQVFQKTPTAHAIQIVSQYDIAYARIDVRGTG 644
Query: 645 FKGKEFRSIVRGNLGDVESTDQILAAKLYGQN-SYVNKEKISLFGWSYGGYLTLKTLEKD 703
+G + + V LGD E D + + + ++++++I++ GWSYGG+LT K KD
Sbjct: 645 GRGWDVKEAVYRKLGDAEVVDTLDMIRAFINTFGFIDEDRIAVMGWSYGGFLTSKIAIKD 704
Query: 704 AGKHFKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMH 763
G+ K +S+APVTD+ YDS YTERY+ P +N +GY V T ++LL H
Sbjct: 705 QGELVKCAISIAPVTDFKYYDSAYTERYLGQPAENLQGYINTNVIPHARNVTNVKYLLAH 764
Query: 764 GTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQY 804
G DDNVH+QNS ++ + L N I ++ V+ + HS+ +
Sbjct: 765 GERDDNVHYQNSARWSEALQQNGI-HFTQLVYANEAHSLSH 804
>7293308 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 1048
Score = 177 bits (450), Expect = 5e-44
Identities = 177/712 (24%), Positives = 296/712 (40%), Gaps = 134/712 (18%)
Query: 211 IVYVKGNDIYLYSSDSHETSKRITNDGSE--------LVFNGKPDWVYEE--EVLEGDTA 260
I +V NDIY E RIT GS +VFNG PDW+YE E+ ++
Sbjct: 251 IAFVHHNDIYYKPKVQGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELESRRSS 310
Query: 261 LWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPINKLNI 320
+ +SP G +LAF N++ V E+ + + + YP + +YPK+GS NP +N+
Sbjct: 311 MEFSPDGLFLAFLSYNDSEVNEYKYTWMGDDIK----YPAVMSQRYPKTGSRNPNVTVNV 366
Query: 321 YDLSADKV---SQI---DSTSDDSLITEVTWVGNHEIIAKVSDRSSDILTVIMVDAADGS 374
+LS K +QI S+ S + +TW + ++ V++R T ++ A
Sbjct: 367 VNLSVIKYIFPTQIKLPSELSNGSYVGGLTWASSTDLSVTVTNREQTKATTVLCRAPHFH 426
Query: 375 RSEVSRIEESDGGWWEITHKTTFVPKDKSRSR---------------------------- 406
V + GW + + F +++ +R
Sbjct: 427 CQAVHTEVTINDGWVLPSERPIFSVRNQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTT 486
Query: 407 ---SYNGYI-DLVPV-DG----YNHLVYFTTNVTTEIPSVVLTSGEWEVVDGPAAFDEEF 457
S GY+ +PV DG Y H+V+ ++ +P LT G +EV + +DE
Sbjct: 487 HEISNGGYLLKRLPVRDGEHGHYRHVVFISSLDRRPVP---LTMGRFEVTE-IVGWDEPH 542
Query: 458 NNVYFIAT-KKSSTERHLYYVNL----------------------ERPQKVYAVTDERLN 494
VYF+A +K ERHLY ++L + + Y + R++
Sbjct: 543 EIVYFMAAPEKRPGERHLYKISLKLNVTESNRTYITSTSPTCLTCDNTESTYRLHRARIS 602
Query: 495 G--------------------------YYSASFSAGARFLLLNYLGPDVPYQKIIDLKSD 528
+ FS + + LGP+ P +++ S+
Sbjct: 603 QRGDRWEDIVARLEPDDCLYDIPKNCLFNRVQFSQDYSYYVQECLGPEAPSVYLVETASN 662
Query: 529 TKDKNIRGNIIGKTLYYLEKNEKLHNSLKRYAIP-ARIFRELTLGKDQNGSDIIVNSYEI 587
K +Y L + L + L + AIP +R F + ++G V +
Sbjct: 663 DK------------IYVLNAGDVLRHRLSQLAIPQSRTFSV----EIRHGFHAQVRLF-- 704
Query: 588 LPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKG 647
LP +P+ P SQ V + F + +N +ASQ IV +DGRG+GF+G
Sbjct: 705 LPPGMREEEDVAFPLVLHVDASPGSQLVTERFHVDWNWYLASQRSFIVAQIDGRGSGFQG 764
Query: 648 KEFRSIVRGNLGDVESTDQI-LAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGK 706
+ R+ V G LG VE DQ+ + L +++ +I FGW YGGY + L D+ +
Sbjct: 765 ELLRTQVHGKLGTVEVEDQLGVLTYLRDNLKFIDPLRICAFGWGYGGYASSMMLIDDSQQ 824
Query: 707 HFKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMHGTA 766
+ V++ P+ ++ + S +TERY+ + + +LMHGTA
Sbjct: 825 VLQCAVAINPIVNFGFHYSFFTERYIPLKGDYLRALQEADLTMKAGNIKGRNLMLMHGTA 884
Query: 767 DDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNW 818
D VH +++L + L ++ + V+PD DH+I ++V K + W
Sbjct: 885 DTLVHQEHTLMLVRALVEQQVK-FRHQVYPDEDHAIARSLSHVY---KTMEW 932
>At5g24260 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 746
Score = 166 bits (419), Expect = 2e-40
Identities = 153/634 (24%), Positives = 279/634 (43%), Gaps = 40/634 (6%)
Query: 197 SEISIAKWSPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSELVFNGKPDWVYEEEVLE 256
S I + SPN + YV+ +++++ + ++T + + + +G +++ +EE ++
Sbjct: 138 SPIIDPRLSPNGLFLAYVRESELHVLNLLKNQTQQLTSGANGSTLSHGLAEYIAQEE-MD 196
Query: 257 GDTALWWSPTGDYLAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPIN 316
WWS ++A+ +++ + + F I + + + + A + YP +G+ N
Sbjct: 197 RRNGYWWSLDSKFIAYTEVDSSQIPLFRIMHQGKRSVGSEAQEDHA---YPFAGALNSTL 253
Query: 317 KLNIYDLSAD-KVSQID------STSDDSLITEVTWVGNHEIIAKVSDRSSDILTVIMVD 369
+L + + K + ++ ++D + V W+ + +I +V +RS L +I D
Sbjct: 254 RLGVVSSAGGGKTTWMNLVCGGRGNTEDEYLGRVNWLPGNVLIVQVLNRSQSKLKIISFD 313
Query: 370 AADGSRSEVSRIEESDGGWWEITHKTTFVPKDK-SRSRSYNGYIDLVPVDGYNHLVYFTT 428
G + V EESD W H F P +K SR G+I G+ HL + +
Sbjct: 314 INTG-QGNVLLTEESDT--WVTLHDC-FTPLEKVPSSRGSGGFIWASERTGFRHLYLYES 369
Query: 429 NVTTEIPSVVLTSGEWEVVDGPAAFDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAV 488
+ T +TSGEW +V+ A +E + VYF T E +LY LE
Sbjct: 370 DGTC---LGAITSGEW-MVEQIAGVNEPMSLVYFTGTLDGPLETNLYCAKLEAGNTSRCQ 425
Query: 489 TDERLNGYYSASFSAGARFLLLNYLGPD-VPYQKIIDLKSDTKDKNIRGNIIGKTLYYLE 547
+G G ++L++ + V +D ++ + K LY
Sbjct: 426 PMRLTHG-------KGKHIVVLDHQMKNFVDIHDSVDSPPRVSLCSLSDGTVLKILYEQT 478
Query: 548 KNEKLHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAY 607
++ SLK P + + GK + + Y+ + F P Y Y
Sbjct: 479 SPIQILKSLKLEP-PEFVQIQANDGK----TTLYGAVYKPDSSKFGPP---PYKTMINVY 530
Query: 608 GGPNSQQVAQTF--GIGFNQVIASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTD 665
GGP+ Q V ++ + +V +D RGT +G +F S ++ N G V++ D
Sbjct: 531 GGPSVQLVYDSWINTVDMRTQYLRSRGILVWKLDNRGTARRGLKFESWMKHNCGYVDAED 590
Query: 666 QILAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLYDS 725
Q+ AK + + I ++GWSYGGYL+ L + + F VS APVT W YDS
Sbjct: 591 QVTGAKWLIEQGLAKPDHIGVYGWSYGGYLSATLLTRYP-EIFNCAVSGAPVTSWDGYDS 649
Query: 726 VYTERYMHTPQKNPEGYDKCKVHNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLNLN 785
YTE+YM P + +H+ + +L+HG D+NVHF+++ + ++ L +
Sbjct: 650 FYTEKYMGLPTEEERYLKSSVMHHVGNLTDKQKLMLVHGMIDENVHFRHTARLVNAL-VE 708
Query: 786 NIENYDVHVFPDSDHSIQYHNANVIVFNKILNWI 819
+ Y++ +FPD H + + + +I +I
Sbjct: 709 AGKRYELLIFPDERHMPRKKKDRIYMEQRIWEFI 742
>Hs18450280 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 882
Score = 163 bits (413), Expect = 9e-40
Identities = 178/677 (26%), Positives = 288/677 (42%), Gaps = 120/677 (17%)
Query: 211 IVYVKGNDIYLYSSDSHETSKRITNDGSELV-------FNGKPDWVYEEEVLEGDTALWW 263
I ++ NDI++ + + E +R+T +EL G +V +EE + + WW
Sbjct: 212 IAFIHSNDIWISNIVTRE-ERRLTYVHNELANMEEDARSAGVATFVLQEE-FDRYSGYWW 269
Query: 264 SPTGDY---------LAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNP 314
P + + + + +E+ VE + + E + ++ +YPK+G++NP
Sbjct: 270 CPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSF------RYPKTGTANP 323
Query: 315 INKLNIYDLSADKVSQIDSTSDDSLIT--EVTWVGNHEIIAKVS-------------DRS 359
+ ++ D +I D LI E+ + G E IA+ DRS
Sbjct: 324 KVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGV-EYIARAGWTPEGKYAWSILLDRS 382
Query: 360 SDILTVIMV-------------------DAADGSRSEVSRIEESDGGWWEITHKTTFVPK 400
L ++++ ++ S + + EE+ W I P+
Sbjct: 383 QTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQ 442
Query: 401 DKSRSRSYNGYIDLVPVD----GYNHLVYFTTNVTTE-----------IPS--------- 436
S+ I+ + G+ HL Y T++ E PS
Sbjct: 443 ------SHEEEIEFIFASECKTGFRHL-YKITSILKESKYKRSSGGLPAPSDFKCPIKEE 495
Query: 437 VVLTSGEWEVVDGPAA---FDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDERL 493
+ +TSGEWEV+ + DE VYF TK S E HLY V+ P +V +TD
Sbjct: 496 IAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDR-- 553
Query: 494 NGY-YSASFSAGARFLLLNYLGPDVPY-QKIIDLKSDTKDKNIRGNIIGKTLYYLEKNEK 551
GY +S S F + Y P+ + L S D + T+
Sbjct: 554 -GYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATIL------D 606
Query: 552 LHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAYGGPN 611
L Y P E T G G Y+ P+D P K YP F YGGP
Sbjct: 607 SAGPLPDYTPPEIFSFESTTGFTLYGM-----LYK--PHDLQPGKK--YPTVLFIYGGPQ 657
Query: 612 SQQVAQTF-GIGFNQV-IASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQILA 669
Q V F G+ + ++ + L +VVV+D RG+ +G +F + +G +E DQ+
Sbjct: 658 VQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEG 717
Query: 670 AK-LYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLYDSVYT 728
+ L + +++ +++ + GWSYGGYL+L L + + F+ ++ APVT W+ YD+ YT
Sbjct: 718 LQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDI-FRVAIAGAPVTLWIFYDTGYT 776
Query: 729 ERYMHTPQKNPEGYDKCKV-HNATAFATVP-RFLLMHGTADDNVHFQNSLKYLDLLNLNN 786
ERYM P +N +GY V A F + P R LL+HG D+NVHF ++ L L +
Sbjct: 777 ERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFL-VRA 835
Query: 787 IENYDVHVFPDSDHSIQ 803
+ YD+ ++P HSI+
Sbjct: 836 GKPYDLQIYPQERHSIR 852
>Hs21040237 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 863
Score = 158 bits (400), Expect = 3e-38
Identities = 169/678 (24%), Positives = 281/678 (40%), Gaps = 124/678 (18%)
Query: 213 YVKGNDIYLYSSDSHETSKRIT--NDGSELVFN-----GKPDWVYEEEVLEGDTALWWSP 265
++ +D+++ + ++ E +R+T + G V + G +V +EE + T WW P
Sbjct: 203 FINNSDLWVANIETGE-ERRLTFCHQGLSNVLDDPKSAGVATFVIQEE-FDRFTGYWWCP 260
Query: 266 TGDY----------LAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNPI 315
T + + + +++E+ VE +P E + +Y +YP++GS NP
Sbjct: 261 TASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSY------RYPRTGSKNPK 314
Query: 316 NKLNIYDLSADKVSQIDSTSDDSL-------------ITEVTWVGNHEII-AKVSDRSSD 361
L + + D +I ST + L I W + + A DR
Sbjct: 315 IALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQ 374
Query: 362 ILTVIMVDAA---DGSRSEVSRI----------------EESDGGWWEITHKTTFVPKDK 402
L ++++ A + +E R+ EE W I F P +
Sbjct: 375 WLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVW--INVHDIFYPFPQ 432
Query: 403 SRSRSYNGYIDLVPVD-GYNHLVYFTTNVTTE-------------------IPSVVLTSG 442
S ++ G+ HL T + ++ + LTSG
Sbjct: 433 SEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSG 492
Query: 443 EWEVVDGPAA---FDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDERLNGYYSA 499
EWEV+ + +EE VYF TK + E HLY V+ E ++ +T + +S
Sbjct: 493 EWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFS--HSC 550
Query: 500 SFSAGARFLLLNYLGPDVPYQKIIDLKSDTKDKNIRGNIIGKTLYYLEKNEKLHNSLKRY 559
S S + +Y P + S D L K + S+
Sbjct: 551 SMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDP------------LHKQPRFWASMMEA 598
Query: 560 A------IPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAYGGPNSQ 613
A +P IF T SD+ + P+ P K +P F YGGP Q
Sbjct: 599 ASCPPDYVPPEIFHFHTR------SDVRLYGMIYKPHALQPGKK--HPTVLFVYGGPQVQ 650
Query: 614 QVAQTF-GIGFNQV-IASQLDAIVVVVDGRGTGFKGKEFRSIVRGNLGDVESTDQI---- 667
V +F GI + ++ + L VVV+DGRG+ +G F ++ +G VE DQ+
Sbjct: 651 LVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQ 710
Query: 668 LAAKLYGQNSYVNKEKISLFGWSYGGYLTLKTLEKDAGKHFKYGVSVAPVTDWLLYDSVY 727
A+ YG +++ ++++ GWSYGG+L+L L + FK ++ APVT W+ YD+ Y
Sbjct: 711 FVAEKYG---FIDLSRVAIHGWSYGGFLSLMGLIHKP-QVFKVAIAGAPVTVWMAYDTGY 766
Query: 728 TERYMHTPQKNPEGYDKCKV--HNATAFATVPRFLLMHGTADDNVHFQNSLKYLDLLNLN 785
TERYM P+ N GY+ V H R L++HG D+NVHF ++ +L +
Sbjct: 767 TERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHT-NFLVSQLIR 825
Query: 786 NIENYDVHVFPDSDHSIQ 803
+ Y + ++P+ HSI+
Sbjct: 826 AGKPYQLQIYPNERHSIR 843
>CE28837 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 927
Score = 118 bits (296), Expect = 3e-26
Identities = 70/247 (28%), Positives = 130/247 (52%), Gaps = 22/247 (8%)
Query: 589 PNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKGK 648
P++FDP K YPVF + YGGP Q V F + +L +VV +D RG+ +G
Sbjct: 680 PSNFDPYKK--YPVFHYVYGGPGIQIVHNDFS-WIQYIRFCRLGYVVVFIDNRGSAHRGI 736
Query: 649 EFRSIVRGNLGDVESTDQILAAKLYGQNS--YVNKEKISLFGWSYGGYLTLKTLEKDAGK 706
EF + +G VE DQ+ ++ + + +++ ++ + GWSYGGY+ L+ + K
Sbjct: 737 EFERHIHKKMGTVEVEDQVEGLQMLAERTGGFMDMSRVVVHGWSYGGYMALQMIAKHPNI 796
Query: 707 HFKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATV--------PR 758
++ ++ V+DW LYD+ YTERYM P + V+ A++ + R
Sbjct: 797 -YRAAIAGGAVSDWRLYDTAYTERYMGYPLEE-------HVYGASSITGLVEKLPDEPNR 848
Query: 759 FLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNW 818
+L+HG D+NVHF + +D + + +++ +FP+ H ++ ++A++ + +++ +
Sbjct: 849 LMLVHGLMDENVHFAHLTHLVDEC-IKKGKWHELVIFPNERHGVRNNDASIYLDARMMYF 907
Query: 819 IRHAYNG 825
+ A G
Sbjct: 908 AQQAIQG 914
>CE17153 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 931
Score = 118 bits (296), Expect = 3e-26
Identities = 70/247 (28%), Positives = 130/247 (52%), Gaps = 22/247 (8%)
Query: 589 PNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGRGTGFKGK 648
P++FDP K YPVF + YGGP Q V F + +L +VV +D RG+ +G
Sbjct: 684 PSNFDPYKK--YPVFHYVYGGPGIQIVHNDFS-WIQYIRFCRLGYVVVFIDNRGSAHRGI 740
Query: 649 EFRSIVRGNLGDVESTDQILAAKLYGQNS--YVNKEKISLFGWSYGGYLTLKTLEKDAGK 706
EF + +G VE DQ+ ++ + + +++ ++ + GWSYGGY+ L+ + K
Sbjct: 741 EFERHIHKKMGTVEVEDQVEGLQMLAERTGGFMDMSRVVVHGWSYGGYMALQMIAKHPNI 800
Query: 707 HFKYGVSVAPVTDWLLYDSVYTERYMHTPQKNPEGYDKCKVHNATAFATV--------PR 758
++ ++ V+DW LYD+ YTERYM P + V+ A++ + R
Sbjct: 801 -YRAAIAGGAVSDWRLYDTAYTERYMGYPLEE-------HVYGASSITGLVEKLPDEPNR 852
Query: 759 FLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVFNKILNW 818
+L+HG D+NVHF + +D + + +++ +FP+ H ++ ++A++ + +++ +
Sbjct: 853 LMLVHGLMDENVHFAHLTHLVDEC-IKKGKWHELVIFPNERHGVRNNDASIYLDARMMYF 911
Query: 819 IRHAYNG 825
+ A G
Sbjct: 912 AQQAIQG 918
>Hs18450278 [O] KOG2281 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
Length = 782
Score = 68.9 bits (167), Expect = 3e-11
Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 3/94 (3%)
Query: 712 VSVAPVTDWLLYDSVYTERYMHTPQKNPEGYDKCKV-HNATAFATVP-RFLLMHGTADDN 769
++ APVT W+ YD+ YTERYM P +N +GY V A F + P R LL+HG D+N
Sbjct: 660 IAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDEN 719
Query: 770 VHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQ 803
VHF ++ L L + + YD+ ++P HSI+
Sbjct: 720 VHFAHTSILLSFL-VRAGKPYDLQIYPQERHSIR 752
Score = 57.4 bits (137), Expect = 9e-08
Identities = 110/479 (22%), Positives = 176/479 (35%), Gaps = 113/479 (23%)
Query: 211 IVYVKGNDIYLYSSDSHETSKRITNDGSELV-------FNGKPDWVYEEEVLEGDTALWW 263
I ++ NDI++ + + E +R+T +EL G +V +EE + + WW
Sbjct: 212 IAFIHSNDIWISNIVTRE-ERRLTYVHNELANMEEDARSAGVATFVLQEE-FDRYSGYWW 269
Query: 264 SPTGDY---------LAFFKINETSVEEFPIPYFVQENQTNSAYPELRKIKYPKSGSSNP 314
P + + + + +E+ VE + + E + ++ +YPK+G++NP
Sbjct: 270 CPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSF------RYPKTGTANP 323
Query: 315 INKLNIYDLSADKVSQIDSTSDDSLIT--EVTWVGNHEIIAKVS-------------DRS 359
+ ++ D +I D LI E+ + G E IA+ DRS
Sbjct: 324 KVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGV-EYIARAGWTPEGKYAWSILLDRS 382
Query: 360 SDILTVIMV-------------------DAADGSRSEVSRIEESDGGWWEITHKTTFVPK 400
L ++++ ++ S + + EE+ W I P+
Sbjct: 383 QTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQ 442
Query: 401 DKSRSRSYNGYIDLVPVD----GYNHLVYFTTNVTTE-----------IPS--------- 436
S+ I+ + G+ HL Y T++ E PS
Sbjct: 443 ------SHEEEIEFIFASECKTGFRHL-YKITSILKESKYKRSSGGLPAPSDFKCPIKEE 495
Query: 437 VVLTSGEWEVVDGPAA---FDEEFNNVYFIATKKSSTERHLYYVNLERPQKVYAVTDERL 493
+ +TSGEWEV+ + DE VYF TK S E HLY V+ P +V +TD
Sbjct: 496 IAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTD--- 552
Query: 494 NGY-YSASFSAGARFLLLNYLGPDVPY-QKIIDLKSDTKDKNIRGNIIGKTLYYLEKNEK 551
GY +S S F + Y P+ + L S D + T+
Sbjct: 553 RGYSHSCCISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATIL------D 606
Query: 552 LHNSLKRYAIPARIFRELTLGKDQNGSDIIVNSYEILPNDFDPSLKNHYPVFFFAYGGP 610
L Y P E T G G Y+ P+D P K YP F YGGP
Sbjct: 607 SAGPLPDYTPPEIFSFESTTGFTLYGM-----LYK--PHDLQPGKK--YPTVLFIYGGP 656
>SPBC1711.12 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 683
Score = 58.2 bits (139), Expect = 5e-08
Identities = 58/249 (23%), Positives = 106/249 (42%), Gaps = 16/249 (6%)
Query: 582 VNSYEILPNDFDPSLKNHYPVFFFAYGGPNSQQVAQTFGIGFNQVIASQLDAIVVVVDGR 641
++++ + P FD S K YPV +GGP ++ +N + + IV +D
Sbjct: 429 IHAWIVKPESFDKSKK--YPVAVLIHGGPQGSWT-DSWSTRWNPAVFANAGFIVFALDPT 485
Query: 642 GTGFKGKEFRSIVRGNLGDVESTDQILAAKLYGQN-SYVNKEKISLFGWSYGGYLTLKTL 700
G+ G+ F + + G D L + + SY + EK+ G SYGGY+
Sbjct: 486 GSTGYGQRFTDSIALDWGGKPYKDIELGVEYIKNHLSYADSEKMVALGASYGGYMINWIQ 545
Query: 701 EKDAGKHFKYGVSVAPVTDWL--------LYDSVYTERYMHTPQKNPEGYDKCKVHNATA 752
G+ F+ V V + L LY S++ + TP +N Y++ N
Sbjct: 546 GHPLGRQFRALVCHDGVFNTLNTFYNTEELYFSIHD--FGGTPWENRVIYERWNPSNFVN 603
Query: 753 FATVPRFLLMHGTADDNVHFQNSLKYLDLLNLNNIENYDVHVFPDSDHSIQYHNANVIVF 812
+ P L++H + D + + ++L I + + VF D +H + + ++
Sbjct: 604 YWATPE-LVIHSSKDYRLTESEGIAAFNVLQYKGIPS-RLLVFEDENHWVIKPDNSLRWH 661
Query: 813 NKILNWIRH 821
++L+WI H
Sbjct: 662 KEVLSWILH 670
>7289544 [O] KOG2100 Dipeptidyl aminopeptidase
Length = 184
Score = 55.5 bits (132), Expect = 3e-07
Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 24/172 (13%)
Query: 96 PEVKPLQWISTPDSHKNDKGLYVTFENDTYSVRSVLDESYSKTLFEGTSFTYDSKNYTVD 155
P P W++T YV F++D S+ +VLD + + T+ T N V
Sbjct: 13 PRRLPSSWVTTQK--------YV-FQSDDGSL-AVLDTTTNLVKVLVTNHTLRQLN--VR 60
Query: 156 AVVASPELSKVLIRSETEKGWRHSTFGTYFVYENDSFHKID-----------SEISIAKW 204
+ S +L VL +K ++ S Y +Y+ + H + + A W
Sbjct: 61 RYLCSSDLKYVLFTHNVKKNFQKSFTAFYTIYDVTNDHHTPVKLKDTLKVQRTRLQYASW 120
Query: 205 SPNSRDIVYVKGNDIYLYSSDSHETSKRITNDGSE-LVFNGKPDWVYEEEVL 255
N+ I++V NDI++ S E RIT+ G E ++NG PDW+Y+ V+
Sbjct: 121 LGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENHIYNGVPDWLYQGRVI 172
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,758,790
Number of Sequences: 60738
Number of extensions: 2447122
Number of successful extensions: 5952
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 5786
Number of HSP's gapped (non-prelim): 38
length of query: 829
length of database: 30,389,216
effective HSP length: 115
effective length of query: 714
effective length of database: 23,404,346
effective search space: 16710703044
effective search space used: 16710703044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)