ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV2958 check: MH U KOG0093 Intracellular trafficking, secretion, and vesicular transport GTPase Rab3, small G protein superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV2958 1028781 1029995 405
(405 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR022c [U] KOG0093 GTPase Rab3 small G protein superfamily 119 8e-27
YNL098c [R] KOG0395 Ras-related GTPase 72 2e-12
YOR101w [R] KOG0395 Ras-related GTPase 71 3e-12
7302995 [R] KOG0395 Ras-related GTPase 71 3e-12
YGR152c [R] KOG0395 Ras-related GTPase 64 4e-10
CE03037 [R] KOG0395 Ras-related GTPase 62 2e-09
Hs5902050 [R] KOG0395 Ras-related GTPase 60 4e-09
7292172 [R] KOG0395 Ras-related GTPase 60 4e-09
Hs4506405 [R] KOG0395 Ras-related GTPase 60 8e-09
Hs10518344 [R] KOG0395 Ras-related GTPase 60 8e-09
CE24846 [R] KOG0395 Ras-related GTPase 59 1e-08
7291733 [R] KOG0395 Ras-related GTPase 59 1e-08
SPAC9E9.07c [TU] KOG0078 GTP-binding protein SEC4 small G protei... 59 1e-08
Hs10880977 [R] KOG0395 Ras-related GTPase 59 1e-08
CE01868 [R] KOG0395 Ras-related GTPase 59 2e-08
SPAC17H9.09c [R] KOG0395 Ras-related GTPase 58 2e-08
Hs7661678 [R] KOG0395 Ras-related GTPase 58 2e-08
CE08025 [R] KOG0395 Ras-related GTPase 58 2e-08
At1g73640 [U] KOG0087 GTPase Rab11/YPT3 small G protein superfamily 58 2e-08
Hs4885569 [R] KOG0395 Ras-related GTPase 58 3e-08
Hs6912514 [R] KOG0395 Ras-related GTPase 57 4e-08
Hs13643777 [R] KOG0395 Ras-related GTPase 57 5e-08
Hs4506533 [R] KOG0395 Ras-related GTPase 57 6e-08
Hs4505451 [R] KOG0395 Ras-related GTPase 57 6e-08
Hs4506417 [R] KOG0395 Ras-related GTPase 56 8e-08
CE20623 [TU] KOG0078 GTP-binding protein SEC4 small G protein su... 56 8e-08
Hs4506413 [R] KOG0395 Ras-related GTPase 55 1e-07
Hs22045303 [R] KOG0395 Ras-related GTPase 55 1e-07
HsM6912698 [R] KOG0395 Ras-related GTPase 55 2e-07
Hs4885425 [R] KOG0395 Ras-related GTPase 55 2e-07
Hs21361416 [R] KOG0395 Ras-related GTPase 55 2e-07
CE25424 [R] KOG0395 Ras-related GTPase 54 3e-07
CE23555 [U] KOG0093 GTPase Rab3 small G protein superfamily 54 4e-07
CE20518 [U] KOG0093 GTPase Rab3 small G protein superfamily 54 4e-07
Hs19923985 [U] KOG0093 GTPase Rab3 small G protein superfamily 54 5e-07
Hs21553323 [R] KOG0395 Ras-related GTPase 53 7e-07
7290433 [R] KOG0395 Ras-related GTPase 53 9e-07
7290026 [R] KOG0395 Ras-related GTPase 53 9e-07
Hs21703367 [R] KOG0395 Ras-related GTPase 52 1e-06
Hs19923264 [U] KOG0081 GTPase Rab27 small G protein superfamily 52 1e-06
7299191 [R] KOG0395 Ras-related GTPase 52 1e-06
Hs15718761 [R] KOG0395 Ras-related GTPase 52 2e-06
Hs14249704 [R] KOG0395 Ras-related GTPase 52 2e-06
Hs4759000 [U] KOG0093 GTPase Rab3 small G protein superfamily 52 2e-06
Hs4506367 [U] KOG0093 GTPase Rab3 small G protein superfamily 52 2e-06
7303712 [U] KOG0093 GTPase Rab3 small G protein superfamily 51 3e-06
7292441 [R] KOG0395 Ras-related GTPase 51 3e-06
At5g59840 [TU] KOG0078 GTP-binding protein SEC4 small G protein ... 51 4e-06
At3g53610 [TU] KOG0078 GTP-binding protein SEC4 small G protein ... 51 4e-06
Hs7657492 [R] KOG0083 GTPase Rab26/Rab37 small G protein superfa... 50 5e-06
ECU03g1560 [R] KOG0393 Ras-related small GTPase Rho type 50 5e-06
Hs22064989 [R] KOG0395 Ras-related GTPase 50 6e-06
Hs15718763 [R] KOG0395 Ras-related GTPase 50 6e-06
YFL005w [TU] KOG0078 GTP-binding protein SEC4 small G protein su... 50 8e-06
Hs20556496_2 [TU] KOG0078 GTP-binding protein SEC4 small G prote... 50 8e-06
>YHR022c [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 256
Score = 119 bits (298), Expect = 8e-27
Identities = 76/242 (31%), Positives = 128/242 (52%), Gaps = 15/242 (6%)
Query: 16 AKLPRQFDVLTSKVALIGNSTVGKTCMVGRWIKGHSVLHDVDETGEHEEDLFHKIIEYDA 75
A +PR FD+ +SK+ ++G+ GKT +V W+ + D + DL+HK I++D
Sbjct: 12 ASIPRCFDLKSSKITVMGDDHSGKTSLVRSWLGSSFQISDANRY--RVSDLYHKTIQFDT 69
Query: 76 LTKS-ANFQECCKLLKHASLDEIKKVSSNVYQNMA------YSDSQNTKYDATLKLDVQV 128
L K F +L +A K S +Y++ ++ + +DVQV
Sbjct: 70 LVKYYRTFGVKGQLPNYAGFKA--KNSGTIYESCGNFLEERLINANKSTAQRRTSIDVQV 127
Query: 129 VDVTHFDATDYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGD---DVPI 185
D + + S+L LQ+ Q+D ILC+D+TN ++LA + Y II ++ + D+PI
Sbjct: 128 FDTNQMEVSYLSELTTLQIRQSDAIILCFDSTNDSSLASLESYICIIHHVRLECELDIPI 187
Query: 186 IVCGTKIDCISERKVSEDEVIGLCEEMGVD-FDTCYFENSAMENINIDETFYAILHLIEK 244
I+ TK D SER ++ ++V+ +E+G + YFE S+ N+N+++ F A+L IEK
Sbjct: 188 IIACTKCDLDSERTITHEKVLTFIQELGFSPGNLDYFETSSKFNVNVEDLFLAVLLKIEK 247
Query: 245 RK 246
K
Sbjct: 248 SK 249
>YNL098c [R] KOG0395 Ras-related GTPase
Length = 322
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/224 (25%), Positives = 102/224 (45%), Gaps = 20/224 (8%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDD-VPIIVCGTKIDCIS 196
+YS +R + +GF+L Y T+ ++L ++ Y++ I R+K D VPI+V G K D +
Sbjct: 70 EYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLEN 129
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIE----KRKLAKTHT 252
E++VS + + + ++M F E SA + IN++E FY + L+ K T
Sbjct: 130 EKQVSYQDGLNMAKQMNAPF----LETSAKQAINVEEAFYTLARLVRDEGGKYNKTLTEN 185
Query: 253 NCCKEPQHHSMANGTVLEKPKFTNYLQSSPASSPLKDSESTAV------SVPPKSPTLGE 306
+ K+ + +G + + S A++ + ST V S+ K+ G
Sbjct: 186 DNSKQTSQDTKGSGANSVPRNSGGHRKMSNAANGKNVNSSTTVVNARNASIESKTGLAGN 245
Query: 307 YST---TSISIPLLDTPTPPS--PAAEQANSIKNFENYREDADE 345
+T T +D T + A+ AN++ N N A +
Sbjct: 246 QATNGKTQTDRTNIDNSTGQAGQANAQSANTVNNRVNNNSKAGQ 289
>YOR101w [R] KOG0395 Ras-related GTPase
Length = 309
Score = 71.2 bits (173), Expect = 3e-12
Identities = 58/276 (21%), Positives = 115/276 (41%), Gaps = 44/276 (15%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDD-VPIIVCGTKIDCIS 196
+YS +R + +GF+L Y T+ + ++ Y++ I R+K D +P++V G K+D +
Sbjct: 70 EYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLEN 129
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTNCCK 256
ER+VS ++ + L +++ F E SA + IN+DE FY+++ L+
Sbjct: 130 ERQVSYEDGLRLAKQLNAPF----LETSAKQAINVDEAFYSLIRLVRD------------ 173
Query: 257 EPQHHSMANGTVLEKPKFTNYLQSSPASSPLKDSESTAVSVPPKSPTLGEYSTTSISIPL 316
+ K+ + + ++ ++DSE T+ S T + S L
Sbjct: 174 -------------DGGKYNSMNRQLDNTNEIRDSELTS------SATADREKKNNGSYVL 214
Query: 317 LDTPTPPSPAAEQANSIKNFENYREDADEKTDMEARFETKRATTIHSMRTMEQXXXXXXX 376
++ T + +++ + + DEK + T +S
Sbjct: 215 DNSLTNAGTGSSSKSAVNHNGETTKRTDEKNYVNQN-NNNEGNTKYSSNGNGNRSDISRG 273
Query: 377 XXXXXXXXKGKRNEKKKRSSSGNT-------CCIIC 405
+ K++ + +++SS N CCIIC
Sbjct: 274 NQNNALNSRSKQSAEPQKNSSANARKESSGGCCIIC 309
>7302995 [R] KOG0395 Ras-related GTPase
Length = 264
Score = 70.9 bits (172), Expect = 3e-12
Identities = 42/164 (25%), Positives = 82/164 (49%), Gaps = 15/164 (9%)
Query: 87 KLLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATDYSDLRHLQ 146
+ + H+ LD + YQ A D++ D ++D +++ +R
Sbjct: 78 QFVSHSFLDYHDPTIEDSYQQQAVIDNEAALLD--------ILDTA--GQVEFTAMRDQY 127
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKVSEDEV 205
+ +GFI+CY T+ + + + Y ++ITR++ +D+P+++ K+D S+R+V+ +E
Sbjct: 128 MRCGEGFIICYSVTDRHSFQEASEYRKLITRVRLSEDIPLVLIANKVDLESQRRVTTEEG 187
Query: 206 IGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAK 249
L + G F FE SA IDE FY ++ I ++++ K
Sbjct: 188 RNLANQFGCPF----FETSAALRHYIDEAFYTLVREIRRKEMHK 227
>YGR152c [R] KOG0395 Ras-related GTPase
Length = 272
Score = 63.9 bits (154), Expect = 4e-10
Identities = 39/142 (27%), Positives = 72/142 (50%), Gaps = 7/142 (4%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y + Y T+++D +V D+ D ++ +R L + GF+L Y T+ +L
Sbjct: 32 YDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLE 91
Query: 167 DMTLYHRIITRIKGDD-VPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSA 225
++ + RIK D VP+++ G K D I+ER +S +E I + + G ++E SA
Sbjct: 92 ELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWG---RVPFYETSA 148
Query: 226 MENINIDETFYAILHLIEKRKL 247
+ N+DE F ++ I + ++
Sbjct: 149 LLRSNVDEVFVDLVRQIIRNEM 170
>CE03037 [R] KOG0395 Ras-related GTPase
Length = 188
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/124 (29%), Positives = 61/124 (48%), Gaps = 11/124 (8%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GF+L Y T +T D+ I R+K D+VP+I+ G K D E
Sbjct: 64 FTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVKDTDEVPMILVGNKCDLEDE 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEK------RKLAKTH 251
R V +D+ L + G + + E SA IN+ E FY ++ I + R+ +++
Sbjct: 124 RVVGKDQGQNLARQFG----SAFLETSAKAKINVSEVFYDLVRQINRRYPESGRRQGQSN 179
Query: 252 TNCC 255
CC
Sbjct: 180 KQCC 183
>Hs5902050 [R] KOG0395 Ras-related GTPase
Length = 219
Score = 60.5 bits (145), Expect = 4e-09
Identities = 33/133 (24%), Positives = 71/133 (52%), Gaps = 8/133 (6%)
Query: 118 YDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRI 174
Y +++D + ++ D +++ +R + +GFI+CY T+ + ++ + ++
Sbjct: 58 YKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQL 117
Query: 175 ITRIKG-DDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDE 233
I R++ DD P+++ G K D R+V+++E + L E F +FE SA ID+
Sbjct: 118 IYRVRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALARE----FSCPFFETSAAYRYYIDD 173
Query: 234 TFYAILHLIEKRK 246
F+A++ I +++
Sbjct: 174 VFHALVREIRRKE 186
>7292172 [R] KOG0395 Ras-related GTPase
Length = 184
Score = 60.5 bits (145), Expect = 4e-09
Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GF+L Y T +T D+ I R+K DDVP+++ G K D E
Sbjct: 64 FTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEE 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAK 249
R V ++ L + + F+ + E SA +N+++ FY ++ I K+ K
Sbjct: 124 RVVGKE----LGKNLATQFNCAFMETSAKAKVNVNDIFYDLVRQINKKSPEK 171
>Hs4506405 [R] KOG0395 Ras-related GTPase
Length = 206
Score = 59.7 bits (143), Expect = 8e-09
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 9/145 (6%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y ++ Y + LD + V + D DY+ +R +GF+L + T +
Sbjct: 43 YEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFT 102
Query: 167 DMTLYHRIITRIKG--DDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENS 224
+ I R+K D +P++V G K D R+V +E EE GV Y E S
Sbjct: 103 ATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPVEEARSKAEEWGVQ----YVETS 158
Query: 225 AMENINIDETFYAILHLIEKRKLAK 249
A N+D+ F+ ++ I +K+++
Sbjct: 159 AKTRANVDKVFFDLMREIRTKKMSE 183
>Hs10518344 [R] KOG0395 Ras-related GTPase
Length = 183
Score = 59.7 bits (143), Expect = 8e-09
Identities = 38/118 (32%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GFIL Y N + D+ I R+K + VP+I+ G K+D SE
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLESE 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTNCC 255
R+VS E L EE G F E SA +DE F I+ + CC
Sbjct: 124 REVSSSEGRALAEEWGCPF----METSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCC 177
>CE24846 [R] KOG0395 Ras-related GTPase
Length = 212
Score = 59.3 bits (142), Expect = 1e-08
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCIS 196
++S +R + GF++ + T+ + ++ H +I RIK DD PII+ G K D +
Sbjct: 77 EFSTMREQYLRTGSGFLIVFAVTDRNSFEEVKKLHELICRIKDRDDFPIILVGNKADLEN 136
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEK 244
ER V+ E EE+ Y E SA N+DE F+ I+ L+ K
Sbjct: 137 ERHVARHE----AEELAHRLSIPYLECSAKIRKNVDEAFFDIVRLVRK 180
>7291733 [R] KOG0395 Ras-related GTPase
Length = 182
Score = 59.3 bits (142), Expect = 1e-08
Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 8/120 (6%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDD-VPIIVCGTKIDCISE 197
++ +R L + GFI+ Y TN T D++ +ITR+KG PI++ K D +
Sbjct: 64 FASMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQ 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAI---LHLIEKRKLAKTHTNC 254
R+VS E L + +D + E SA + IN++E F I ++L ++ + K + C
Sbjct: 124 REVSTAEGNALAQL----WDCPFIEASAKDRINVNEVFATIVREMNLTQENRQKKNYCCC 179
>SPAC9E9.07c [TU] KOG0078 GTP-binding protein SEC4 small G protein superfamily
and related Ras family GTP-binding proteins
Length = 200
Score = 58.9 bits (141), Expect = 1e-08
Identities = 36/130 (27%), Positives = 67/130 (50%), Gaps = 7/130 (5%)
Query: 121 TLKLDVQVVDVTHFDATDYSDLRHLQV---NQADGFILCYDTTNPATLADMTLYHRIITR 177
T++LD + + + +D R + A G +L YD T+ + ++ + + +
Sbjct: 50 TIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTDKKSFDNVRTWFSNVEQ 109
Query: 178 IKGDDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYA 237
++V I+ G K DC +R+VS ++ L +E+GV F E SA N+N+DE F+
Sbjct: 110 HASENVYKILIGNKCDCEDQRQVSFEQGQALADELGVKF----LEASAKTNVNVDEAFFT 165
Query: 238 ILHLIEKRKL 247
+ I+K+K+
Sbjct: 166 LAREIKKQKI 175
>Hs10880977 [R] KOG0395 Ras-related GTPase
Length = 183
Score = 58.9 bits (141), Expect = 1e-08
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GFIL Y N + D+ I R+K + VP+I+ G K+D E
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPE 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTNCC 255
R+V E L +E G F E SA +DE F I+ + L + CC
Sbjct: 124 REVMSSEGRALAQEWGCPF----METSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCC 177
>CE01868 [R] KOG0395 Ras-related GTPase
Length = 219
Score = 58.5 bits (140), Expect = 2e-08
Identities = 37/128 (28%), Positives = 69/128 (53%), Gaps = 9/128 (7%)
Query: 126 VQVVDVTHFDATDYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGD---D 182
+Q+ D T + + ++ L +++ + FIL Y TN + A++ ++ +KG+ +
Sbjct: 81 LQITDTT--GSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAE 138
Query: 183 VPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLI 242
PI++ G K D S+R+VS + +++ + + + E SA N NI E F +L L
Sbjct: 139 TPIMLVGNKKDEESKREVSSNS----GQKVATNMECGFIETSAKNNENITELFQQLLALE 194
Query: 243 EKRKLAKT 250
+KR+LA T
Sbjct: 195 KKRQLALT 202
>SPAC17H9.09c [R] KOG0395 Ras-related GTPase
Length = 219
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/108 (27%), Positives = 59/108 (53%), Gaps = 5/108 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDDV-PIIVCGTKIDCIS 196
+YS +R + +GF+L Y+ T+ ++ +++ +++ I R+K D P+++ K D +
Sbjct: 68 EYSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEA 127
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEK 244
ER VS E E++ Y E SA +N++E FY+++ I +
Sbjct: 128 ERVVSRAE----GEQLAKSMHCLYVETSAKLRLNVEEAFYSLVRTIRR 171
>Hs7661678 [R] KOG0395 Ras-related GTPase
Length = 184
Score = 58.2 bits (139), Expect = 2e-08
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 7/140 (5%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y + Y +++D Q + D ++ +R L + GF L Y T +T
Sbjct: 32 YDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFN 91
Query: 167 DMTLYHRIITRIKG-DDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSA 225
D+ I R+K DDVP+I+ G K D ER V +++ L + + + E+SA
Sbjct: 92 DLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWN---NCAFLESSA 148
Query: 226 MENINIDETFYAILHLIEKR 245
IN++E FY ++ I ++
Sbjct: 149 KSKINVNEIFYDLVRQINRK 168
>CE08025 [R] KOG0395 Ras-related GTPase
Length = 173
Score = 58.2 bits (139), Expect = 2e-08
Identities = 51/207 (24%), Positives = 89/207 (42%), Gaps = 44/207 (21%)
Query: 28 KVALIGNSTVGKTCMVGRWIKGHSVLHDVDETGEHEEDLFHKIIEYDALTKSANFQECCK 87
K+ ++GN VGK+ + ++++G V H D T ED + K+ + DA
Sbjct: 5 KIVVLGNGGVGKSALTLQYVQGIFV-HTYDAT---IEDSYRKLSKVDA------------ 48
Query: 88 LLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATD-YSDLRHLQ 146
++A L+ + T+KL +Q ++ H + ++ +R
Sbjct: 49 --ENARLEILDTAG-------------------TVKLSIQ--EIQHMLIQEQFTGMRETY 85
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVI 206
A GF+L + +T ++ I I+G +VP+I+ G K D R+V E E
Sbjct: 86 YRTAQGFVLVFSLAETSTFENLKQTFTDIIAIRGKEVPMILVGNKSDLAETRQVDESEAH 145
Query: 207 GLCEEMGVDFDTCYFENSAMENINIDE 233
E++ + YFE SA N N+ E
Sbjct: 146 NFAEKLKIP----YFETSARLNQNVSE 168
>At1g73640 [U] KOG0087 GTPase Rab11/YPT3 small G protein superfamily
Length = 233
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/145 (27%), Positives = 66/145 (44%), Gaps = 8/145 (5%)
Query: 152 GFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLCEE 211
G +L YD T T ++ + + + +++ G K D R+V EDE L E
Sbjct: 88 GALLIYDITRRTTFDNIKKWLFELRDFANPETVVVLVGNKSDLRQSREVEEDEGKTLAES 147
Query: 212 MGVDFDTCYFENSAMENINIDETFYAIL----HLIEKRKLAKTHTNCCKEPQHHSMANGT 267
G+ F E SA+EN+N++E F ++ ++ +R ++ +N P + NGT
Sbjct: 148 EGLYF----LETSALENVNVEEAFLVMIGRIHEVVTQRIASENKSNGAATPHINGNGNGT 203
Query: 268 VLEKPKFTNYLQSSPASSPLKDSES 292
VL K + A+ PL S S
Sbjct: 204 VLPVGKEIVNIHEVTATQPLLSSSS 228
>Hs4885569 [R] KOG0395 Ras-related GTPase
Length = 209
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 8/142 (5%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y ++ Y + LD + V + D DY+ +R +GF+ + T + A
Sbjct: 46 YEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFA 105
Query: 167 DMTLYHRIITRIKGDD-VPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSA 225
+ I R+K D+ VP ++ G K D +R+VS +E E+ V+ Y E SA
Sbjct: 106 ATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVN----YVETSA 161
Query: 226 MENINIDETFYAILHLIEKRKL 247
N+D+ F+ ++ I RK+
Sbjct: 162 KTRANVDKVFFDLMREIRARKM 183
>Hs6912514 [R] KOG0395 Ras-related GTPase
Length = 208
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/132 (25%), Positives = 68/132 (51%), Gaps = 6/132 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCIS 196
++S +R + DGF++ Y T+ A+ + +H++I R+K + P+I+ K+D +
Sbjct: 73 EFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMH 132
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAME-NINIDETFYAILHLIEKRKLAKTHTNCC 255
RK++ ++ +EM + Y E SA + +N+D+ F+ ++ +I ++ K+
Sbjct: 133 LRKITREQ----GKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKSQKKKK 188
Query: 256 KEPQHHSMANGT 267
K A GT
Sbjct: 189 KTKWRGDRATGT 200
>Hs13643777 [R] KOG0395 Ras-related GTPase
Length = 133
Score = 57.0 bits (136), Expect = 5e-08
Identities = 33/108 (30%), Positives = 55/108 (50%), Gaps = 4/108 (3%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GF L Y T +T D+ I R+K DDVP+I+ G K D E
Sbjct: 13 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDE 72
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKR 245
R V +++ L + + + E+SA IN++E FY ++ I ++
Sbjct: 73 RVVGKEQGQNLARQWN---NCAFLESSAKSKINVNEIFYDLVRQINRK 117
>Hs4506533 [R] KOG0395 Ras-related GTPase
Length = 217
Score = 56.6 bits (135), Expect = 6e-08
Identities = 28/110 (25%), Positives = 61/110 (55%), Gaps = 5/110 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGD-DVPIIVCGTKIDCIS 196
+++ +R + +GFI+CY T+ + + + +I +++ ++P+++ G KID
Sbjct: 80 EFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLEQ 139
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRK 246
R+VS +E + L +E ++ +FE SA ID+ F+ ++ I K++
Sbjct: 140 FRQVSTEEGLSLAQE----YNCGFFETSAALRFCIDDAFHGLVREIRKKE 185
>Hs4505451 [R] KOG0395 Ras-related GTPase
Length = 189
Score = 56.6 bits (135), Expect = 6e-08
Identities = 39/168 (23%), Positives = 77/168 (45%), Gaps = 16/168 (9%)
Query: 87 KLLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATDYSDLRHLQ 146
+L+++ +DE + Y+ D + D ++D + +YS +R
Sbjct: 22 QLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLD--------ILDTAGQE--EYSAMRDQY 71
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKVSEDEV 205
+ +GF+ + N + AD+ LY I R+K DDVP+++ G K D + R V +
Sbjct: 72 MRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCD-LPTRTVDTKQA 130
Query: 206 IGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTN 253
L + G+ F E SA +++ FY ++ I + ++ K +++
Sbjct: 131 HELAKSYGIPF----IETSAKTRQGVEDAFYTLVREIRQYRMKKLNSS 174
>Hs4506417 [R] KOG0395 Ras-related GTPase
Length = 183
Score = 56.2 bits (134), Expect = 8e-08
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GFIL Y N + D+ I R+K + VP+I+ G K+D E
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGE 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTNCC 255
R+VS E L EE F E SA ++DE F I+ + + CC
Sbjct: 124 REVSYGEGKALAEEWSCPF----METSAKNKASVDELFAEIVRQMNYAAQSNGDEGCC 177
>CE20623 [TU] KOG0078 GTP-binding protein SEC4 small G protein superfamily
and related Ras family GTP-binding proteins
Length = 224
Score = 56.2 bits (134), Expect = 8e-08
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Query: 121 TLKLDVQVVDVTHFDATDYSDLRHLQV---NQADGFILCYDTTNPATLADMTLYHRIITR 177
T++LD + + + +D R + A G IL YD TN + ++ + R I
Sbjct: 49 TIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEE 108
Query: 178 IKGDDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYA 237
DV ++ G K D R+VS D E++ +++ T + E SA N+NIDE F+
Sbjct: 109 HAASDVERMIIGNKCDIEERREVSRDR----GEQLAIEYGTKFLETSAKANLNIDEAFFT 164
Query: 238 ILHLIEKR 245
+ I+ +
Sbjct: 165 LARDIKSK 172
>Hs4506413 [R] KOG0395 Ras-related GTPase
Length = 184
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 7/140 (5%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y + Y +++D Q + D ++ +R L + GF L Y T +T
Sbjct: 32 YDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFN 91
Query: 167 DMTLYHRIITRIKG-DDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSA 225
D+ I R+K +DVP+I+ G K D ER V +++ L + + + E+SA
Sbjct: 92 DLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQW---CNCAFLESSA 148
Query: 226 MENINIDETFYAILHLIEKR 245
IN++E FY ++ I ++
Sbjct: 149 KSKINVNEIFYDLVRQINRK 168
>Hs22045303 [R] KOG0395 Ras-related GTPase
Length = 183
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/118 (30%), Positives = 52/118 (43%), Gaps = 5/118 (4%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCISE 197
++ +R L + GFIL Y N + D+ I R+K + VP+I+ G K+D E
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGE 123
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTNCC 255
R+VS E L EE F E SA ++DE F I+ + CC
Sbjct: 124 REVSYGEGKALAEEWSCPF----METSAKNKASVDELFAEIVRQMNYAAQPNGDEGCC 177
>HsM6912698 [R] KOG0395 Ras-related GTPase
Length = 203
Score = 54.7 bits (130), Expect = 2e-07
Identities = 29/108 (26%), Positives = 59/108 (53%), Gaps = 5/108 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCIS 196
++ +R + +GF+L + T+ + ++ + R I R+K D+ P+I+ G K D
Sbjct: 73 EFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDH 132
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEK 244
+R+V+++E L ++ V Y E SA +N+D+ F+ ++ +I K
Sbjct: 133 QRQVTQEEGQQLARQLKV----TYMEASAKIRMNVDQAFHELVRVIRK 176
>Hs4885425 [R] KOG0395 Ras-related GTPase
Length = 189
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/164 (23%), Positives = 72/164 (43%), Gaps = 16/164 (9%)
Query: 87 KLLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATDYSDLRHLQ 146
+L+++ +DE + Y+ D + D ++D + +YS +R
Sbjct: 22 QLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLD--------ILDTAGQE--EYSAMRDQY 71
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKVSEDEV 205
+ +GF+ + N + D+ Y I R+K DDVP+++ G K D ++ R V +
Sbjct: 72 MRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCD-LAARTVESRQA 130
Query: 206 IGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAK 249
L G+ Y E SA +++ FY ++ I + KL K
Sbjct: 131 QDLARSYGIP----YIETSAKTRQGVEDAFYTLVREIRQHKLRK 170
>Hs21361416 [R] KOG0395 Ras-related GTPase
Length = 204
Score = 54.7 bits (130), Expect = 2e-07
Identities = 29/108 (26%), Positives = 59/108 (53%), Gaps = 5/108 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCIS 196
++ +R + +GF+L + T+ + ++ + R I R+K D+ P+I+ G K D
Sbjct: 74 EFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDH 133
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEK 244
+R+V+++E L ++ V Y E SA +N+D+ F+ ++ +I K
Sbjct: 134 QRQVTQEEGQQLARQLKV----TYMEASAKIRMNVDQAFHELVRVIRK 177
>CE25424 [R] KOG0395 Ras-related GTPase
Length = 213
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 9/142 (6%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y ++ Y + LD + + D DYS +R +GFI + + +
Sbjct: 46 YEPTKADSYRKKVVLDGEECSIDILDTAGQEDYSAIRDNYYRSGEGFICVFSILDMESFE 105
Query: 167 DMTLYHRIITRIKGDD--VPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENS 224
+ I R+K D VPI++ G K D +R VS + LC + + Y E S
Sbjct: 106 ATNEFREQILRVKNSDSSVPIVLVGNKGDMRDQRVVSAE----LCRQRAEQWGCHYVETS 161
Query: 225 AMENINIDETFYAILHLIEKRK 246
A N+D+ FY ++ +++RK
Sbjct: 162 AKRRENVDKVFYDLMREMKRRK 183
>CE23555 [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 233
Score = 53.9 bits (128), Expect = 4e-07
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A GFIL YD TN + + + I ++ +++ G K D SER VS D L
Sbjct: 109 AMGFILMYDITNEESFNSVQDWCTQIKTYSWENAQVVLVGNKCDMDSERVVSMDRGRQLA 168
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLI 242
+++G++F FE SA ENIN+ F ++ +I
Sbjct: 169 DQLGLEF----FETSAKENINVKAVFEKLVEII 197
>CE20518 [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 219
Score = 53.9 bits (128), Expect = 4e-07
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A GFIL YD TN + + + I ++ +++ G K D SER VS D L
Sbjct: 95 AMGFILMYDITNEESFNSVQDWCTQIKTYSWENAQVVLVGNKCDMDSERVVSMDRGRQLA 154
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLI 242
+++G++F FE SA ENIN+ F ++ +I
Sbjct: 155 DQLGLEF----FETSAKENINVKAVFEKLVEII 183
>Hs19923985 [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 227
Score = 53.5 bits (127), Expect = 5e-07
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A GFIL YD TN + + + I D+ +I+ G K D ER +S + L
Sbjct: 103 AMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLG 162
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLI 242
E++G +F FE SA +NIN+ +TF ++ +I
Sbjct: 163 EQLGFEF----FETSAKDNINVKQTFERLVDII 191
>Hs21553323 [R] KOG0395 Ras-related GTPase
Length = 198
Score = 53.1 bits (126), Expect = 7e-07
Identities = 32/125 (25%), Positives = 67/125 (53%), Gaps = 9/125 (7%)
Query: 126 VQVVDVTHFDATDYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG--DDV 183
+Q+ D T + + ++ L +++ FIL + T+ +L ++ +++I +IKG +D+
Sbjct: 57 LQITDTT--GSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDI 114
Query: 184 PIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIE 243
P+++ G K D ++R+V E + +E + + E SA N N+ E F +L L
Sbjct: 115 PVMLVGNKCD-ETQREVDTREAQAVAQE----WKCAFMETSAKMNYNVKELFQELLTLET 169
Query: 244 KRKLA 248
+R ++
Sbjct: 170 RRNMS 174
>7290433 [R] KOG0395 Ras-related GTPase
Length = 201
Score = 52.8 bits (125), Expect = 9e-07
Identities = 35/141 (24%), Positives = 61/141 (42%), Gaps = 8/141 (5%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDAT---DYSDLRHLQVNQADGFILCYDTTNPATLA 166
Y ++ Y + LD + V + D DY+ +R +GF+ + T+ +
Sbjct: 40 YEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITDDESFQ 99
Query: 167 DMTLYHRIITRIKGDD-VPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSA 225
+ I R+K D+ +P ++ G K D +RKV E C+ + Y E SA
Sbjct: 100 ATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSE----CQLRAQQWAVPYVETSA 155
Query: 226 MENINIDETFYAILHLIEKRK 246
N+D+ F+ ++ I RK
Sbjct: 156 KTRENVDKVFFDLMREIRSRK 176
>7290026 [R] KOG0395 Ras-related GTPase
Length = 319
Score = 52.8 bits (125), Expect = 9e-07
Identities = 33/107 (30%), Positives = 52/107 (47%), Gaps = 2/107 (1%)
Query: 135 DATDYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDD-VPIIVCGTKID 193
D ++R L ++ AD FIL YD T+ T ++ I K VPI+V G KID
Sbjct: 117 DTAGSYEMRALSISSADAFILVYDVTDATTFEEVRTIRDQIHETKATTAVPIVVVGNKID 176
Query: 194 CISERKVSEDEVIGLCEE-MGVDFDTCYFENSAMENINIDETFYAIL 239
+++ + + E + VD++ + E SA N NI + F +L
Sbjct: 177 LLADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELL 223
>Hs21703367 [R] KOG0395 Ras-related GTPase
Length = 199
Score = 52.4 bits (124), Expect = 1e-06
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 126 VQVVDVTHFDATDYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGD--DV 183
+Q+ D T + + ++ L +++ FIL Y T+ +L ++ + I IKGD +
Sbjct: 57 LQITDTT--GSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESI 114
Query: 184 PIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIE 243
PI++ G K D R+V E E + + + E SA N N+ E F +L+L +
Sbjct: 115 PIMLVGNKCDESPSREVQSSE----AEALARTWKCAFMETSAKLNHNVKELFQELLNLEK 170
Query: 244 KRKLA 248
+R ++
Sbjct: 171 RRTVS 175
>Hs19923264 [U] KOG0081 GTPase Rab27 small G protein superfamily
Length = 221
Score = 52.4 bits (124), Expect = 1e-06
Identities = 32/97 (32%), Positives = 50/97 (50%), Gaps = 5/97 (5%)
Query: 150 ADGFILCYDTTNPATLADMTLY-HRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGL 208
A GF+L +D TN + ++ + ++ ++ I++CG K D +R V E+E I L
Sbjct: 92 AMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIAL 151
Query: 209 CEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKR 245
E+ G+ YFE SA NI + +L LI KR
Sbjct: 152 AEKYGIP----YFETSAANGTNISQAIEMLLDLIMKR 184
>7299191 [R] KOG0395 Ras-related GTPase
Length = 189
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/161 (21%), Positives = 75/161 (45%), Gaps = 16/161 (9%)
Query: 87 KLLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATDYSDLRHLQ 146
+L+++ +DE + Y+ D + D ++D + +YS +R
Sbjct: 22 QLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLD--------ILDTAGQE--EYSAMRDQY 71
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKVSEDEV 205
+ +GF+L + + + D+ Y I R+K ++VP+++ G K D ++ V+ ++
Sbjct: 72 MRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCD-LASWNVNNEQA 130
Query: 206 IGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRK 246
+ ++ G+ Y E SA + +D+ FY ++ I K K
Sbjct: 131 REVAKQYGIP----YIETSAKTRMGVDDAFYTLVREIRKDK 167
>Hs15718761 [R] KOG0395 Ras-related GTPase
Length = 188
Score = 52.0 bits (123), Expect = 2e-06
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 16/161 (9%)
Query: 87 KLLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATDYSDLRHLQ 146
+L+++ +DE + Y+ D + D ++D + +YS +R
Sbjct: 22 QLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLD--------ILDTAGQE--EYSAMRDQY 71
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKVSEDEV 205
+ +GF+ + N + D+ Y I R+K +DVP+++ G K D + R V +
Sbjct: 72 MRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCD-LPSRTVDTKQA 130
Query: 206 IGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRK 246
L G+ F E SA +D+ FY ++ I K K
Sbjct: 131 QDLARSYGIPF----IETSAKTRQGVDDAFYTLVREIRKHK 167
>Hs14249704 [R] KOG0395 Ras-related GTPase
Length = 199
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/165 (24%), Positives = 69/165 (40%), Gaps = 6/165 (3%)
Query: 110 YSDSQNTKYDATLKLDVQVVDVTHFDATDYSDL--RHLQVNQADGFILCYDTTNPATLAD 167
Y + + Y +D +VV + D D R + +GF+L YD T+ + +
Sbjct: 35 YDPTLESTYRHQATIDDEVVSMEILDTAGQEDTIQREGHMRWGEGFVLVYDITDRGSFEE 94
Query: 168 MTLYHRIITRI-KGDDVPIIVCGTKIDCISERKVSEDEVIGLCEEMGVDFDTCYFENSAM 226
+ I+ I K +V +I+ G K D R+VS +E L E+ F C ++
Sbjct: 95 VLPLKNILDEIKKPKNVTLILVGNKADLDHSRQVSTEEGEKLATELACAFYEC---SACT 151
Query: 227 ENINIDETFYAILHLIEKRKLAKTHTNCCKEPQHHSMANGTVLEK 271
NI E FY + + +R++ + T H A +L K
Sbjct: 152 GEGNITEIFYELCREVRRRRMVQGKTRRRSSTTHVKQAINKMLTK 196
>Hs4759000 [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 219
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/117 (30%), Positives = 57/117 (47%), Gaps = 10/117 (8%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A GF+L YD N + A + + I D+ +I+ G K D ER V ++ L
Sbjct: 95 AMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLA 154
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHTNCCKEPQHHSMANG 266
+++G +F FE SA ENIN+ + F ++ +I ++ N EP S +NG
Sbjct: 155 DDLGFEF----FEASAKENINVKQVFERLVDVICEK------MNESLEPSSSSGSNG 201
>Hs4506367 [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 220
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A GFIL YD TN + + + I D+ +++ G K D ER VS + L
Sbjct: 95 AMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLA 154
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLI 242
+ +G +F FE SA +NIN+ +TF ++ +I
Sbjct: 155 DHLGFEF----FEASAKDNINVKQTFERLVDVI 183
>7303712 [U] KOG0093 GTPase Rab3 small G protein superfamily
Length = 220
Score = 51.2 bits (121), Expect = 3e-06
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 4/93 (4%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A GFIL YD TN + + + I D+ +I+ G K D +R +S + L
Sbjct: 94 AMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLA 153
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLI 242
+++GV+F FE SA EN+N+ F ++ +I
Sbjct: 154 DQLGVEF----FETSAKENVNVKAVFERLVDII 182
>7292441 [R] KOG0395 Ras-related GTPase
Length = 195
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/113 (23%), Positives = 61/113 (53%), Gaps = 5/113 (4%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKG-DDVPIIVCGTKIDCIS 196
++S +R + +GF+L + + ++ ++ + R I R+K D+ P+++ G K D
Sbjct: 68 EFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKH 127
Query: 197 ERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAK 249
+++VS +E + + Y E SA +N+D+ F+ ++ ++ K ++A+
Sbjct: 128 QQQVSLEEAQNTSRNLMIP----YIECSAKLRVNVDQAFHELVRIVRKFQIAE 176
>At5g59840 [TU] KOG0078 GTP-binding protein SEC4 small G protein superfamily
and related Ras family GTP-binding proteins
Length = 216
Score = 50.8 bits (120), Expect = 4e-06
Identities = 40/134 (29%), Positives = 69/134 (50%), Gaps = 9/134 (6%)
Query: 121 TLKLDVQVVDVTHFDATDYSDLRHLQV---NQADGFILCYDTTNPATLADMTLYHRIITR 177
T++LD + + + +D R + A G +L YD T+ ++ ++ + R I +
Sbjct: 56 TIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWIRNIEQ 115
Query: 178 IKGDDVPIIVCGTKIDCI-SERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFY 236
D+V I+ G K D S+R V + + L +E G+ F FE SA N+N++E F+
Sbjct: 116 HASDNVNKILVGNKADMDESKRAVPKSKGQALADEYGIKF----FETSAKTNLNVEEVFF 171
Query: 237 AILHLIEKRKLAKT 250
+I I K++LA T
Sbjct: 172 SIAKDI-KQRLADT 184
>At3g53610 [TU] KOG0078 GTP-binding protein SEC4 small G protein superfamily
and related Ras family GTP-binding proteins
Length = 216
Score = 50.8 bits (120), Expect = 4e-06
Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 11/143 (7%)
Query: 121 TLKLDVQVVDVTHFDATDYSDLRHLQV---NQADGFILCYDTTNPATLADMTLYHRIITR 177
T++LD + + + +D R + A G +L YD T+ ++ ++ + R I +
Sbjct: 56 TIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWIRNIEQ 115
Query: 178 IKGDDVPIIVCGTKIDCI-SERKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFY 236
D V I+ G K D S+R V + + L +E G+ F FE SA N+N++E F+
Sbjct: 116 HASDSVNKILVGNKADMDESKRAVPKSKGQALADEYGMKF----FETSAKTNLNVEEVFF 171
Query: 237 AILHLIEKRKLAKTHTNCCKEPQ 259
+I I K++LA T EPQ
Sbjct: 172 SIAKDI-KQRLADTDARA--EPQ 191
>Hs7657492 [R] KOG0083 GTPase Rab26/Rab37 small G protein superfamily
Length = 190
Score = 50.4 bits (119), Expect = 5e-06
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISER 198
+ + H A +L YD TN A+ ++ + I DV +++ G K+D ER
Sbjct: 60 FRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSAHER 119
Query: 199 KVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKL 247
V ++ L +E G+ F E SA +N+D F AI +++R +
Sbjct: 120 VVKREDGEKLAKEYGLPF----METSAKTGLNVDLAFTAIAKELKQRSM 164
>ECU03g1560 [R] KOG0393 Ras-related small GTPase Rho type
Length = 179
Score = 50.4 bits (119), Expect = 5e-06
Identities = 35/121 (28%), Positives = 60/121 (48%), Gaps = 8/121 (6%)
Query: 138 DYSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISE 197
+Y+ LR+L + D F++CY N + + R + + +VP+I+CGTK D I
Sbjct: 63 EYNKLRNLSFQETDVFLVCYAVNNILSFHNT---RRWVEELARYNVPMILCGTKCDIIDG 119
Query: 198 RKVSEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAKTHT--NCC 255
V ++ + L +E G+ E S++E IN+ + F L K + +K + CC
Sbjct: 120 NIVDKELPVQLSKEYGLYGS---MECSSVELINVKKVFDIALEAALKPRKSKFRSIWFCC 176
Query: 256 K 256
K
Sbjct: 177 K 177
>Hs22064989 [R] KOG0395 Ras-related GTPase
Length = 123
Score = 50.1 bits (118), Expect = 6e-06
Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 6/109 (5%)
Query: 142 LRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKV 200
+R + +GF+ + N + D+ Y I R+K DDVP+++ G K D ++ R V
Sbjct: 1 MRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCD-LAARTV 59
Query: 201 SEDEVIGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAK 249
+ L G+ Y E SA +++ FY ++ I + KL K
Sbjct: 60 ESRQAQDLARSYGIP----YIETSAKTRQGVEDAFYTLVREIRQHKLRK 104
>Hs15718763 [R] KOG0395 Ras-related GTPase
Length = 189
Score = 50.1 bits (118), Expect = 6e-06
Identities = 37/164 (22%), Positives = 71/164 (42%), Gaps = 16/164 (9%)
Query: 87 KLLKHASLDEIKKVSSNVYQNMAYSDSQNTKYDATLKLDVQVVDVTHFDATDYSDLRHLQ 146
+L+++ +DE + Y+ D + D ++D + +YS +R
Sbjct: 22 QLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLD--------ILDTAGQE--EYSAMRDQY 71
Query: 147 VNQADGFILCYDTTNPATLADMTLYHRIITRIK-GDDVPIIVCGTKIDCISERKVSEDEV 205
+ +GF+ + N + D+ Y I R+K +DVP+++ G K D + R V +
Sbjct: 72 MRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCD-LPSRTVDTKQA 130
Query: 206 IGLCEEMGVDFDTCYFENSAMENINIDETFYAILHLIEKRKLAK 249
L G+ F E SA +++ FY ++ I + +L K
Sbjct: 131 QDLARSYGIPF----IETSAKTRQRVEDAFYTLVREIRQYRLKK 170
>YFL005w [TU] KOG0078 GTP-binding protein SEC4 small G protein superfamily
and related Ras family GTP-binding proteins
Length = 215
Score = 49.7 bits (117), Expect = 8e-06
Identities = 27/96 (28%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Query: 150 ADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISERKVSEDEVIGLC 209
A G IL YD T+ T ++ + + + D+ +++ G K D + R V+ D+ L
Sbjct: 93 AMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSD-METRVVTADQGEALA 151
Query: 210 EEMGVDFDTCYFENSAMENINIDETFYAILHLIEKR 245
+E+G+ F E+SA + N++E F+ + LI+++
Sbjct: 152 KELGIPF----IESSAKNDDNVNEIFFTLAKLIQEK 183
>Hs20556496_2 [TU] KOG0078 GTP-binding protein SEC4 small G protein superfamily
and related Ras family GTP-binding proteins
Length = 514
Score = 49.7 bits (117), Expect = 8e-06
Identities = 26/81 (32%), Positives = 42/81 (51%)
Query: 139 YSDLRHLQVNQADGFILCYDTTNPATLADMTLYHRIITRIKGDDVPIIVCGTKIDCISER 198
Y + + +ADG +L YD T+ + A + + + D V I++ G K+DC ER
Sbjct: 90 YHSMTRQLLRKADGVVLMYDITSQESFAHVRYWLDCLQDAGSDGVVILLLGNKMDCEEER 149
Query: 199 KVSEDEVIGLCEEMGVDFDTC 219
+VS + L +E+GV F C
Sbjct: 150 QVSVEAGQQLAQELGVYFGEC 170
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,419,260
Number of Sequences: 60738
Number of extensions: 1069887
Number of successful extensions: 5075
Number of sequences better than 1.0e-05: 55
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 4978
Number of HSP's gapped (non-prelim): 78
length of query: 405
length of database: 30,389,216
effective HSP length: 109
effective length of query: 296
effective length of database: 23,768,774
effective search space: 7035557104
effective search space used: 7035557104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)