ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3040 good U KOG3771 Intracellular trafficking, secretion, and vesicular transport Amphiphysin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3040 1054430 1055227 266
(266 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCR009c [U] KOG3771 Amphiphysin 424 e-119
SPBC725.09c [U] KOG3771 Amphiphysin 303 2e-82
Hs8923904 [U] KOG3771 Amphiphysin 97 2e-20
SPBC21D10.12 [U] KOG3771 Amphiphysin 91 1e-18
Hs4502081 [U] KOG3771 Amphiphysin 85 9e-17
Hs21536423 [U] KOG3771 Amphiphysin 85 9e-17
YDR388w [U] KOG3771 Amphiphysin 85 1e-16
Hs4757748 [U] KOG3771 Amphiphysin 78 1e-14
Hs21536417 [U] KOG3771 Amphiphysin 78 1e-14
Hs21536415 [U] KOG3771 Amphiphysin 78 1e-14
Hs21536413 [U] KOG3771 Amphiphysin 78 1e-14
Hs21536411 [U] KOG3771 Amphiphysin 78 1e-14
Hs21536409 [U] KOG3771 Amphiphysin 78 1e-14
Hs21536407 [U] KOG3771 Amphiphysin 78 1e-14
CE03428 [U] KOG3771 Amphiphysin 69 9e-12
Hs7706487 [U] KOG3771 Amphiphysin 67 3e-11
7303429 [U] KOG3771 Amphiphysin 64 2e-10
Hs7705296 [U] KOG3771 Amphiphysin 64 3e-10
Hs21536404 [U] KOG3771 Amphiphysin 62 8e-10
Hs21536402 [U] KOG3771 Amphiphysin 62 8e-10
Hs21536400 [U] KOG3771 Amphiphysin 62 8e-10
>YCR009c [U] KOG3771 Amphiphysin
Length = 265
Score = 424 bits (1090), Expect = e-119
Identities = 207/263 (78%), Positives = 237/263 (89%)
Query: 1 MSWEGFKKAINRAGNSVLIKNVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRA 60
MSWEGFKKAINRAG+SV+IKNVDKT DK+Y MEERRY+VL++AG+ LQKEAKG+LDSLRA
Sbjct: 1 MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGEALQKEAKGFLDSLRA 60
Query: 61 VTASQVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPI 120
VTASQ TIAEVIS+LYDDSK + +N+GNYYLQCV+DFD+ETVKQLDGP RETVL+PI
Sbjct: 61 VTASQTTIAEVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSETVKQLDGPLRETVLDPI 120
Query: 121 TKFATYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYD 180
TKF+TYF EIE AIKKR+HKKQD+DAAKAKVRRL+DKPAKDA+KLPRAEKEL+ AKDI++
Sbjct: 121 TKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKDASKLPRAEKELSLAKDIFE 180
Query: 181 NLNDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLAQIQQYLDQQSRDDYAN 240
NLN+QLK ELPQLVSLRVPY+DPSFEAL+KIQLRFCT+GYTRLAQIQQYLDQQSRDDYAN
Sbjct: 181 NLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTRLAQIQQYLDQQSRDDYAN 240
Query: 241 GXXXXXXXXXXXXMSNLNICALG 263
G M++L+ICALG
Sbjct: 241 GLLDTKIEELLGQMTSLDICALG 263
>SPBC725.09c [U] KOG3771 Amphiphysin
Length = 264
Score = 303 bits (776), Expect = 2e-82
Identities = 150/264 (56%), Positives = 191/264 (71%), Gaps = 6/264 (2%)
Query: 1 MSWEGFKKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSL 58
MSW GFKKA+NRAG SV++K +V++T D+++ EERRYR +E A K+LQKEAKGYLD+L
Sbjct: 1 MSWHGFKKAVNRAGTSVMMKTGHVERTVDREFETEERRYRTMESAAKKLQKEAKGYLDAL 60
Query: 59 RAVTASQVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLE 118
RA+TASQ IA I Y D+ S + YY Q V D D +TVK+LDGPFR TVL+
Sbjct: 61 RAMTASQTRIANTIDAFYGDA----GSKDGVSAYYRQVVEDLDADTVKELDGPFRTTVLD 116
Query: 119 PITKFATYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDI 178
PI++F +YF +I AI KR HK D+DA +AKV++L+DKP+ D TKLPR EKE A AK++
Sbjct: 117 PISRFCSYFPDINAAITKRNHKLLDHDAMRAKVQKLVDKPSNDTTKLPRTEKEAAMAKEV 176
Query: 179 YDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLAQIQQYLDQQSRDDY 238
Y+ LN+QL ELPQL++LRVPY DPSFEALVKIQLRFC EGY ++AQ+QQY D R+DY
Sbjct: 177 YETLNNQLVSELPQLIALRVPYLDPSFEALVKIQLRFCREGYEKMAQVQQYFDNSVREDY 236
Query: 239 ANGXXXXXXXXXXXXMSNLNICAL 262
+NG M +L+I L
Sbjct: 237 SNGLLDDKVEQVLQSMRDLSIAGL 260
>Hs8923904 [U] KOG3771 Amphiphysin
Length = 253
Score = 97.4 bits (241), Expect = 2e-20
Identities = 67/240 (27%), Positives = 125/240 (51%), Gaps = 13/240 (5%)
Query: 1 MSWEGFKKAINRAGNSVLIKNVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRA 60
MSW FK I + ++ K V++ +++YG + + LE+ + LQK+ K D+ A
Sbjct: 1 MSWIPFK--IGQPKKQIVPKTVERDFEREYG----KLQQLEEQTRRLQKDMKKSTDADLA 54
Query: 61 VTASQVTIA-EVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEP 119
++ S V I+ +++S+ + + + ++ + F+ E V Q+ ++TV+EP
Sbjct: 55 MSKSAVKISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQI----QKTVIEP 110
Query: 120 ITKFATYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDAT--KLPRAEKELAFAKD 177
+ KF + F + A+K+RE QDY +AKV + +K KL +A +EL ++
Sbjct: 111 LKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVRE 170
Query: 178 IYDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLAQIQQYLDQQSRDD 237
++ N QL E+P+ R+ Y+ PSFE+L++ Q+ + +E + + LDQ D
Sbjct: 171 DFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSD 230
>SPBC21D10.12 [U] KOG3771 Amphiphysin
Length = 466
Score = 91.3 bits (225), Expect = 1e-18
Identities = 68/248 (27%), Positives = 115/248 (45%), Gaps = 18/248 (7%)
Query: 1 MSWEGFKKAINRAGNSVLIK-NVDK-THDKDYGMEERRYRVLEKAGKELQKEAKGYLDSL 58
MSW+GF KA+ R ++ K NV + T D Y RR++ LE K+L ++AK Y D++
Sbjct: 1 MSWKGFTKALARTPQTLRSKFNVGEITKDPIYEDAGRRFKSLETEAKKLAEDAKKYTDAI 60
Query: 59 RAVTASQVTIAEVISDLYD---------DSKATSASAHNI--GNYYLQCVRDFDTETVKQ 107
+ Q+ A+ ++Y +S +A I Y + V D +
Sbjct: 61 NGLLNHQIGFADACIEIYKPISGRASDPESYEQEGNAEGIEAAEAYKEIVYDLQKNLASE 120
Query: 108 LDGPFRETVLEPITKFATYFDEIETAIKKREHKKQDYDAAKAKVRRLI---DKPAKDATK 164
+D ++ P + +++ + KR+HK+ DYD ++ ++L DK KD K
Sbjct: 121 MD-VINTRIVNPTGELLKIVKDVDKLLLKRDHKQLDYDRHRSSFKKLQEKKDKSLKDEKK 179
Query: 165 LPRAEKELAFAKDIYDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLA 224
L AE + Y+ N+ LK ELP+L +L + P F+ +QL Y +++
Sbjct: 180 LYEAETAFEQSSQEYEYYNEMLKEELPKLFALAQSFIAPLFQGFYYMQLNVYYVLYEKMS 239
Query: 225 QIQ-QYLD 231
+ QY D
Sbjct: 240 HCEIQYFD 247
>Hs4502081 [U] KOG3771 Amphiphysin
Length = 695
Score = 85.1 bits (209), Expect = 9e-17
Identities = 57/214 (26%), Positives = 104/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K +NRA VL K D+T D+ + + ++ E G LQ+E +GYL +++ + +
Sbjct: 14 QKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEA 73
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ + E + ++Y+ +G DF + V DG L + +
Sbjct: 74 SMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLV---DGS-----LLTLDTYL 125
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I+ I KR K DYD+A+ + L KD +++ +AE+E A+ +++ N
Sbjct: 126 GQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNV 185
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L S RV +Y +F+ + ++ +F E
Sbjct: 186 DLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKE 219
>Hs21536423 [U] KOG3771 Amphiphysin
Length = 653
Score = 85.1 bits (209), Expect = 9e-17
Identities = 57/214 (26%), Positives = 104/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K +NRA VL K D+T D+ + + ++ E G LQ+E +GYL +++ + +
Sbjct: 14 QKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEA 73
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ + E + ++Y+ +G DF + V DG L + +
Sbjct: 74 SMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLV---DGS-----LLTLDTYL 125
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I+ I KR K DYD+A+ + L KD +++ +AE+E A+ +++ N
Sbjct: 126 GQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNV 185
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L S RV +Y +F+ + ++ +F E
Sbjct: 186 DLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKE 219
>YDR388w [U] KOG3771 Amphiphysin
Length = 482
Score = 84.7 bits (208), Expect = 1e-16
Identities = 72/251 (28%), Positives = 113/251 (44%), Gaps = 18/251 (7%)
Query: 1 MSWEGFKKAINRAGNSVL--IKNVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSL 58
MS++GF KA++RA S K ++T D Y ERR++ LE+ K+L +E+K Y ++
Sbjct: 1 MSFKGFTKAVSRAPQSFRQKFKMGEQTEDPVYEDAERRFQELEQETKKLSEESKRYSTAV 60
Query: 59 RAVTASQVTIAEVISDLY-------DDSKATSASAHNIG----NYYLQCVRDFDTETVKQ 107
+ Q+ A+ + +++ D AT + G Y V + ET+K
Sbjct: 61 NGMLTHQIGFAKSMEEIFKPISGKMSDPNATIPEDNPQGIEASEQYRAIVAELQ-ETLKP 119
Query: 108 LDGPFRETVLEPITKFATYFDEIETAIKKREHKKQDYDA---AKAKVRRLIDKPAKDATK 164
E ++ P + I KR HKK D D K + + AKD +
Sbjct: 120 DLALVEEKIVTPCQELLKIITYIRKMATKRNHKKLDLDRHLNTYNKHEKKKEPTAKDEER 179
Query: 165 LPRAEKELAFAKDIYDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLA 224
L +A+ ++ A+ YD ND LK +LP L SL + P F + +QL Y RL
Sbjct: 180 LYKAQAQVEVAQQEYDYYNDLLKTQLPILFSLEAEFVKPLFVSFYFMQLNIFYTLYNRLQ 239
Query: 225 QIQ-QYLDQQS 234
++ Y D S
Sbjct: 240 DMKIPYFDLNS 250
>Hs4757748 [U] KOG3771 Amphiphysin
Length = 454
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>Hs21536417 [U] KOG3771 Amphiphysin
Length = 409
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>Hs21536415 [U] KOG3771 Amphiphysin
Length = 439
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>Hs21536413 [U] KOG3771 Amphiphysin
Length = 475
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>Hs21536411 [U] KOG3771 Amphiphysin
Length = 482
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>Hs21536409 [U] KOG3771 Amphiphysin
Length = 518
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>Hs21536407 [U] KOG3771 Amphiphysin
Length = 497
Score = 78.2 bits (191), Expect = 1e-14
Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F +I++ I KR K DYD+A+ L KD K+ +AE+EL A+ +++ +N
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNV 190
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
L+ ELP L + RV +Y +F+++ ++ F E
Sbjct: 191 DLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKE 224
>CE03428 [U] KOG3771 Amphiphysin
Length = 461
Score = 68.6 bits (166), Expect = 9e-12
Identities = 56/233 (24%), Positives = 104/233 (44%), Gaps = 19/233 (8%)
Query: 7 KKAINRAGNSVL--IKNVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
KKA NR +L I T D+ + K+ ++L K+ K Y +LR + ++
Sbjct: 10 KKATNRTKEKLLEGIGKAKATQDEVFDQHAANLNKQSKSCEKLHKDVKNYSSALRTLLSA 69
Query: 65 QVTIAEVISDLYD----DSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPI 120
+ + + I D Y+ D + +A N+ D +T +L+ + + + +
Sbjct: 70 EKQLRDTIRDAYEPEWPDREHLTAIFDNL-----------DIQT-NELEKTVCDDLPQTV 117
Query: 121 TKFATYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKD-ATKLPRAEKELAFAKDIY 179
T++ F +++ I+KR K DYD+AK + KD KL +A EL A+ +Y
Sbjct: 118 TQYVNQFPDLKKKIEKRGRKLVDYDSAKNSFNSVKASSKKDNDPKLAKATMELQAAEQMY 177
Query: 180 DNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLAQIQQYLDQ 232
+N++L LP + R+ ++ + + L + T+ QI LD+
Sbjct: 178 TEMNNELLEILPAVFDSRITFFVDTLQTLFNANSVYQTDASKFHKQIVMQLDK 230
>Hs7706487 [U] KOG3771 Amphiphysin
Length = 565
Score = 66.6 bits (161), Expect = 3e-11
Identities = 49/214 (22%), Positives = 99/214 (45%), Gaps = 10/214 (4%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K +RA VL K +T D+ + + + G +L K+ K +L +++ + S
Sbjct: 18 QKKFSRAQEKVLQKLGKAVETKDERFEQSANNFYQQQAEGHKLYKDLKNFLSAVKVMHES 77
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
++E + ++Y S+ G+ L+ + + + + + + + +
Sbjct: 78 SKRVSETLQEIY--------SSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYV 129
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F EI+ I KR K DYD+A+ + + + KD K +AE+E A+ ++++LN
Sbjct: 130 AQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQ 189
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
+L ELP L + R+ Y F+ + ++ F E
Sbjct: 190 ELLEELPILYNSRIGCYVTIFQNISNLRDVFYRE 223
>7303429 [U] KOG3771 Amphiphysin
Length = 602
Score = 64.3 bits (155), Expect = 2e-10
Identities = 52/230 (22%), Positives = 97/230 (41%), Gaps = 12/230 (5%)
Query: 7 KKAINRAGNSVL--IKNVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K RA +L + VD+T D+ + + + + LQKE Y+ +RA A+
Sbjct: 14 QKHAGRAKEKILQNLGKVDRTADEIFDDHLNNFNRQQASANRLQKEFNNYIRCVRAAQAA 73
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
T+ + + ++Y+ + G LQ + VL P+ +
Sbjct: 74 SKTLMDSVCEIYEPQWS--------GYDALQAQTGASESLWADFAHKLGDQVLIPLNTYT 125
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRL--IDKPAKDATKLPRAEKELAFAKDIYDNL 182
F E++ ++KR K DYD + + L KD KL + ++L A+ Y+ L
Sbjct: 126 GQFPEMKKKVEKRNRKLIDYDGQRHSFQNLQANANKRKDDVKLTKGREQLEEARRTYEIL 185
Query: 183 NDQLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTEGYTRLAQIQQYLDQ 232
N +L ELP L R+ + + + L + F E ++++ +D+
Sbjct: 186 NTELHDELPALYDSRILFLVTNLQTLFATEQVFHNETAKIYSELEAIVDK 235
>Hs7705296 [U] KOG3771 Amphiphysin
Length = 564
Score = 63.5 bits (153), Expect = 3e-10
Identities = 49/214 (22%), Positives = 98/214 (44%), Gaps = 11/214 (5%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K +RA VL K +T D+ + + + G +L K+ K +L +++ + S
Sbjct: 18 QKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHES 77
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
++E + ++Y S+ G+ L+ + + + + + + + +
Sbjct: 78 SKRVSETLQEIY--------SSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYV 129
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPRAEKELAFAKDIYDNLND 184
F EI+ I KR K DYD+A+ + + KD K +AE+E A+ ++++LN
Sbjct: 130 AQFSEIKERIAKRGRKLVDYDSARHHLEA-VQNAKKDEAKTAKAEEEFNKAQTVFEDLNQ 188
Query: 185 QLKLELPQLVSLRVPYYDPSFEALVKIQLRFCTE 218
+L ELP L + R+ Y F+ + ++ F E
Sbjct: 189 ELLEELPILYNSRIGCYVTIFQNISNLRDVFYRE 222
>Hs21536404 [U] KOG3771 Amphiphysin
Length = 506
Score = 62.0 bits (149), Expect = 8e-10
Identities = 56/245 (22%), Positives = 101/245 (40%), Gaps = 41/245 (16%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPR----------------- 167
F +I++ I KR K DYD+A+ L KD K+ +
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKL 190
Query: 168 --------------AEKELAFAKDIYDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQL 213
AE+EL A+ +++ +N L+ ELP L + RV +Y +F+++ ++
Sbjct: 191 QAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEE 250
Query: 214 RFCTE 218
F E
Sbjct: 251 NFHKE 255
>Hs21536402 [U] KOG3771 Amphiphysin
Length = 550
Score = 62.0 bits (149), Expect = 8e-10
Identities = 56/245 (22%), Positives = 101/245 (40%), Gaps = 41/245 (16%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPR----------------- 167
F +I++ I KR K DYD+A+ L KD K+ +
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKL 190
Query: 168 --------------AEKELAFAKDIYDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQL 213
AE+EL A+ +++ +N L+ ELP L + RV +Y +F+++ ++
Sbjct: 191 QAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEE 250
Query: 214 RFCTE 218
F E
Sbjct: 251 NFHKE 255
>Hs21536400 [U] KOG3771 Amphiphysin
Length = 593
Score = 62.0 bits (149), Expect = 8e-10
Identities = 56/245 (22%), Positives = 101/245 (40%), Gaps = 41/245 (16%)
Query: 7 KKAINRAGNSVLIK--NVDKTHDKDYGMEERRYRVLEKAGKELQKEAKGYLDSLRAVTAS 64
+K + RA VL K D+T D+ + + + G LQK+ + YL S++A+ +
Sbjct: 19 QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEA 78
Query: 65 QVTIAEVISDLYDDSKATSASAHNIGNYYLQCVRDFDTETVKQLDGPFRETVLEPITKFA 124
+ E + ++Y+ A+ I D+ + V Q L + +
Sbjct: 79 SKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQ--------ALLTMDTYL 130
Query: 125 TYFDEIETAIKKREHKKQDYDAAKAKVRRLIDKPAKDATKLPR----------------- 167
F +I++ I KR K DYD+A+ L KD K+ +
Sbjct: 131 GQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKL 190
Query: 168 --------------AEKELAFAKDIYDNLNDQLKLELPQLVSLRVPYYDPSFEALVKIQL 213
AE+EL A+ +++ +N L+ ELP L + RV +Y +F+++ ++
Sbjct: 191 QAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEE 250
Query: 214 RFCTE 218
F E
Sbjct: 251 NFHKE 255
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,555,403
Number of Sequences: 60738
Number of extensions: 570059
Number of successful extensions: 2307
Number of sequences better than 1.0e-05: 21
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2267
Number of HSP's gapped (non-prelim): 21
length of query: 266
length of database: 30,389,216
effective HSP length: 104
effective length of query: 162
effective length of database: 24,072,464
effective search space: 3899739168
effective search space used: 3899739168
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)