ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3087 good S KOG1851 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3087 1068487 1074930 2148
(2148 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFL007w [S] KOG1851 Uncharacterized conserved protein 1641 0.0
YFL006w [S] KOG1851 Uncharacterized conserved protein 188 7e-47
Hs14724070 [S] KOG1851 Uncharacterized conserved protein 63 5e-09
At3g13330 [S] KOG1851 Uncharacterized conserved protein 55 1e-06
CE05284 [S] KOG1851 Uncharacterized conserved protein 54 2e-06
>YFL007w [S] KOG1851 Uncharacterized conserved protein
Length = 1804
Score = 1641 bits (4250), Expect = 0.0
Identities = 817/1821 (44%), Positives = 1214/1821 (65%), Gaps = 44/1821 (2%)
Query: 7 NSNIKSPLPTRSVRSRLFKGLRMYEDKRSASTAEFDVKKTKLTNGLNIPHIQSPGRARSA 66
+ +IKSP+P + K + S+S E KK++L PH SP RARSA
Sbjct: 6 DDDIKSPIPITNKTLSQLKRFERSPGRPSSSQGEIKRKKSRLYAADGRPH--SPLRARSA 63
Query: 67 TPTL-----VHGFMNEDTMKERLAHYNLDFVEDTEEHRANIHDPTSKWFGRRVKPGVELE 121
TPTL +G + + ERL HY LD+V D +H NI+DP+S+WF R V+P +E
Sbjct: 64 TPTLQDQKLFNGMDSTSLLNERLQHYTLDYVSDRAQHMKNIYDPSSRWFSRSVRPEFPIE 123
Query: 122 DLLPYEIESHLDQAKYLYHIVTNLYVAIKSMDVQGLISITSQDLLALKNEVYDLALNSDM 181
+ LPY+ ESH DQAKYL H++ NLY+AI S+D+QGLISI+S+DL LK EV DLAL +D+
Sbjct: 124 EFLPYKTESHEDQAKYLCHVLVNLYIAISSLDIQGLISISSKDLADLKKEVDDLALKTDL 183
Query: 182 FRLVQDVTDDP---HDVAKFXXXXXXXXXXXXXXNEFLDAANPDFGVSGKLTARSTAVIN 238
FRL + ++ +D+A + +E+ D A PDF +GK+TA+S ++N
Sbjct: 184 FRLSNNTAENDLLGNDIADYDDAEGLEDEL----DEYFDLAGPDFNATGKITAKSATIVN 239
Query: 239 VNHWTNELKNCMHFEFPLTLRKALAVVYYNLCLVRGQKVYRQLHLEMFEKLVACDDEGTD 298
VNHWTNELKNC+HF+FP+ LRK+LA VYY L LV+GQKVYRQ+H++MFE+LV+ DD+ T+
Sbjct: 240 VNHWTNELKNCLHFDFPVALRKSLATVYYYLSLVQGQKVYRQMHVDMFERLVSLDDDRTN 299
Query: 299 FTRELKKIGLALDYKPMKDLLNEFLPTVEPDYKMYNVESRSDLSLFRLLVMLSTIARPFF 358
FT L+K GL LD++ M + L EFLP +PDY Y + S+ DL LFRLL+ + A+PFF
Sbjct: 300 FTELLQKQGLLLDHQIMLNFLCEFLPYPDPDYARYELSSKEDLQLFRLLLKHAHNAKPFF 359
Query: 359 DENDETILTDTMDYFLESLAPTTMSVALPSLTCLVPYHYHKNRNVLDYFSVMFSLWSNAT 418
D++ E++L DTM++ L SLAP+TM +P +T +VPYHYH + ++DYF +S+WS+ +
Sbjct: 360 DKSKESLLVDTMNFLLSSLAPSTMMAVMPIVTSVVPYHYHIHSKIIDYFPFCYSIWSSVS 419
Query: 419 ADNSFDTHLYAFVGHAAMDAYYQNILEENPPIISNSNIEFGEHGIFTESQLNFILNRIKN 478
A+ + DTH+Y FVG + D + + + E+ + +EFGE GIFT+ Q+ F+ NR++
Sbjct: 420 ANVAIDTHMYDFVGSISKDVHNKILSSEHEKDVVG--VEFGEFGIFTDDQMTFMFNRLQG 477
Query: 479 HIKEDYQICSFTRVVRPLVYSINGRSPQAFFKKLNELLSSIETYVHPSNSGYWSDIIARF 538
H++ D QI S++R V+P VY+ING FF+KL L +IET++HPSN+G+W+ A+F
Sbjct: 478 HLRTDGQIHSYSRTVKPFVYAINGSKKDRFFEKLVSLAKAIETFIHPSNNGFWTKPNAKF 537
Query: 539 IHGFIRMYHERYMREKKPEAK-YREELKLDEDCHEMLVNSFIELLLVGSQSKHSDLANYY 597
+H FI+ YH R E+ A+ + L CHE +V F+ ++ +GSQ+K+ D+ANYY
Sbjct: 538 VHAFIKSYHGRVKYEEDICARGVTNGICLTSFCHEEIVEIFLNIISLGSQNKNPDIANYY 597
Query: 598 ISCFGYLLDMKPKNGYKICDRIIVDLYDALTDQYVNSEHRLLTSLKQFTRIVRVLIQHEL 657
ISCF YLL++ P N Y I D+I++DLYD L DQ++NS HR+++SLKQFTR++R ++ +L
Sbjct: 598 ISCFAYLLELDPSNAYLIYDKILIDLYDTLADQFINSRHRIISSLKQFTRVIRFIVMDKL 657
Query: 658 YRVHITNILSILIDKIDFNDISLTSNLMNSIVSISCFIPIEVFVKPEEYLTFESNTIPFI 717
YRVHITN+LS+L+ K+D ND +LTSNL+N IVSI+ FIPI+ ++Y++FES+T+P +
Sbjct: 658 YRVHITNVLSMLVSKLDMNDTNLTSNLINGIVSIAAFIPIQDLTGEDDYISFESDTLPLV 717
Query: 718 EEHLFFIKQGGSSPDFEYESSILSDAFRASTTTFENCLKVYVDKLYQLVDVDIDAGLISK 777
++H + IK G SS F + +L++AF+ASTT F++ LKVYV+K++QLVDVD++ L++K
Sbjct: 718 QQHFYHIKCGESSKTFRVDDELLNNAFKASTTVFQSMLKVYVEKIFQLVDVDLEDSLVTK 777
Query: 778 INQTSMIMIQSMDDKMFYYFFGLLEKSFWDNDSFKVKNPLIELVSIPLSAAVKRDIRLSA 837
INQT+MI+ +SMDDK+F YF LL+++FW NDSFK K+P ELV+IPL+A V+R+ LS
Sbjct: 778 INQTTMILQESMDDKIFNYFASLLQRNFWSNDSFKEKDPNYELVTIPLAALVRRNNGLSK 837
Query: 838 RLFRDLDFNIREQIKGGAGSVRSTTEIQPRDVKLATLLSTLNDVLRQSHESILMFGDELI 897
L R L F+I+EQIK GAGSVRST+EIQ RDVKL L+ LNDVLRQ HES+L + DELI
Sbjct: 838 ELVRTLLFHIKEQIKRGAGSVRSTSEIQQRDVKLVLYLTALNDVLRQCHESLLEYSDELI 897
Query: 898 ALLEFIFDNVTNSPLDVINATLLHNALESLTTTEVTDYRLFLQDADVENSEKWGGFQFDR 957
+++++DNVTN PLDVI + ++H+AL +L TTE+TD RLF +D+ + ++WGG QFD
Sbjct: 898 TFMKYLYDNVTNPPLDVITSIVIHSALATLCTTEITDCRLFPEDSKIPEKDRWGGLQFDP 957
Query: 958 RKYLPEFQQIEWHQPSSDEVDFAIKLIDHFYCYAVGMTEKLMDKPQNDFSYVDNMKKNIL 1017
R++ + +WH PSSDE+ +I +++ Y + E+LM P++D Y D ++K +L
Sbjct: 958 RRFDKQHLSFQWHVPSSDEITLSISILESLSEYCINNVEELMKAPRHDSEYGDMIQKYVL 1017
Query: 1018 ILTNILSGSSILYDADYNQNNKSVSNMDPYKKKLLLLQKIRDESCDNNELLVDIEKVRND 1077
++T+ LSGSS+L+D D+N+ ++ SN+ Y++KL+LL+ IR+ +CD EL +DIE++R+
Sbjct: 1018 VMTHTLSGSSLLFDPDFNK-YRTQSNLS-YREKLILLKNIRENNCDPQELDIDIEQIRSG 1075
Query: 1078 TFDADIEMDDSYVDSDSQGNLDINADPGAAE--------HDQLVDYETEPSEAPSGIATP 1129
D D Y++S +++ + G ++ D+L+ E SE PSG+ TP
Sbjct: 1076 KDDED------YIESK---DIEAGLNAGVSDVVQLRDEFPDELIVDEEVVSEMPSGVNTP 1126
Query: 1130 VPRGEEDSNCSMMNSHTAFRDIDVFSYNYFFGRTAAERALDPRYSKIHHLRHEIGLFLHK 1189
+ G ++ S M+S AFRD+D+++ NY+FG T E+ +P+Y ++H +R IG F HK
Sbjct: 1127 I-AGTHGTDNSAMSSDLAFRDLDIYTCNYYFGNTTEEKLQNPQYLQVHRVRARIGHFFHK 1185
Query: 1190 LFKFLNQNYENSTSVFQTLLHGLKVWFTDVGQETIFIDDPKASISVEFLENIQDIAHWEE 1249
L+ FL+ N+EN+T++FQ LLHGLKVWFTD+GQET+F +DP A I V+FLEN+Q ++H E
Sbjct: 1186 LYVFLSTNFENNTNMFQILLHGLKVWFTDLGQETVFNEDPNAFIDVDFLENVQSLSHVNE 1245
Query: 1250 PFLPFTRTYLAADCQELHQSRLTLYSTNRKPSKLELKLLNDVISLSLSVYPNIHRPAQQC 1309
PFTRT A LHQSR+ L+STNRK SKLE LL D+I L+ S+YP+I++PAQ
Sbjct: 1246 ---PFTRTNFAIRANSLHQSRVLLHSTNRKASKLENLLLVDIIQLATSLYPDIYKPAQGT 1302
Query: 1310 MIHVMKQLIGSYSIIVRKVFKAFEAALDSTDAEASKKLEVLIQVLSMKKIQRKMMSDYKN 1369
++H MKQL+GSY +++ K+ + E A+ D K++V++ VL +KKI RK+M+DYK+
Sbjct: 1303 LVHCMKQLVGSYGVVINKIIPSLEKAIKDHD---YMKIQVILNVLLIKKIHRKLMTDYKD 1359
Query: 1370 LEKMLTLLLRASRLDSYFLVSLCDQVMESVSGLIKIPSAVCLFDESAIDCLKPNDETIDK 1429
+ +++ LL+ R++ + D+++ + IKIPS+VC+ + A L P D TI+
Sbjct: 1360 IGRLIFLLIECCRVNELEIGMYADKILTDIVIGIKIPSSVCVISDQAFLPLAPPDGTINL 1419
Query: 1430 QVAVVKTAKDRKRKEYFSQLETLHINLVDFQRKDPQLRWMSICHILRIVQVIQMNLEIKP 1489
QV VK AK +KR+ Y S L L L+D + + W ILR V IQ NLE KP
Sbjct: 1420 QVEAVKLAKKKKREYYLSLLVDLQDKLLDKLDNEKDMGWKIRMFILRFVTQIQSNLESKP 1479
Query: 1490 NQEVLIQSFELTKTKHPSLISNCMVTMLNVCNKMISLGNYNYDIDSTYRTDYVRQYVEYL 1549
++ + TKHP +I + ++L+ CNK+ISL +Y YDI Y+ ++ +VE L
Sbjct: 1480 DKRAVFSIISQISTKHPEIIHLVVKSLLSTCNKIISLSDYEYDITRAYKNEFNPSFVEIL 1539
Query: 1550 DTSKPNFEEEYFKEINNVENPNFFVDSKAFVGWLCRGRPMGVVKAENQIPFNLKPEDMEI 1609
DTS +F + + +E+NN +NP +F+D +A+VGWLC GR M V + + NL+ ++E+
Sbjct: 1540 DTSTTSFPKTFTEEMNNFDNPKYFIDLRAYVGWLCWGRLM-YVMSPKALKLNLRENELEV 1598
Query: 1610 MNNFGKLITKEWLLDMCNIFIRSNEEQSSFSTNRLSLFGIFVHLISNNCCSMKYEDILDI 1669
+ G L+T+E+L D+ ++ NE + FS+ +S F + + LIS+ C + D+ ++
Sbjct: 1599 LKTAGHLLTREFLRDVTMNLVQDNETRGVFSSGNVSFFSLVILLISSGFCELNMSDLFEL 1658
Query: 1670 CEEIYEKDDKSSMIACSEIISGLLFSLKYTDEKNLQKFEKFLERFLGKWLDNNYNATTTD 1729
CE Y KDDK+SMI EI++GL+ K+ +L K + F+E FL K LD N +
Sbjct: 1659 CESYYNKDDKASMIMSVEIVAGLVCGSKFMSVSDLDKRDTFIENFLAKCLDYELNHDAFE 1718
Query: 1730 IWSIVAWWVPSFIDLRRSAQIYKRFLTVDGLFDVKXXXXXXXXGKLIIVTQAISDVGFKM 1789
IWS +AWW+P+ +DLRRS + F+ DG+FD + K+ ++ + + F+
Sbjct: 1719 IWSTLAWWLPAVVDLRRSKTFFCHFINADGMFDRESDAATHQTSKIYMLRSILMSMEFRA 1778
Query: 1790 GSVENLLDQLVFDHPSDVVRR 1810
V L D+LVFDHP D VR+
Sbjct: 1779 PDVGKLFDELVFDHPYDQVRQ 1799
>YFL006w [S] KOG1851 Uncharacterized conserved protein
Length = 254
Score = 188 bits (478), Expect = 7e-47
Identities = 102/249 (40%), Positives = 145/249 (57%), Gaps = 4/249 (1%)
Query: 1903 RVCLGPFAKCYLAPFLMKLDRMRDVCKMVNIKVYSIYVELAYIPISRXXXXXXXXXX-XX 1961
+V L P+ Y+ PFL+ L + +DVC + ++ +Y L Y+PI +
Sbjct: 7 KVLLVPYLVDYVLPFLIGLVKHKDVCALASLDPVRLYAGLGYMPIRKNHVAAIVDYVCSS 66
Query: 1962 XXXXXXHELRVNLTLAEKLFSTQSLVMDHAGKVKILEFVLDKLFCKSFVEVRLKASYVLA 2021
++ ++ L + S + L + K KILEFV+ L+ + FVEVR++A+ +L+
Sbjct: 67 NVALSSNQTKLQLAFIQHFLSAELLQLTEEEKNKILEFVVSNLYNEQFVEVRVRAASILS 126
Query: 2022 GIVHNISYDTDTLHTLLENFKRQL--GSYTFEEKAALSKSNTDIHXXXXXXXXXXEAFPY 2079
IVHN + L +L+E F + L YT +E+ LSK++ IH AFPY
Sbjct: 127 DIVHNWKEEQPLL-SLIERFAKGLDVNKYTSKERQKLSKTDIKIHGNVLGLGAIISAFPY 185
Query: 2080 VSPLPNWIPENMALLASWARTSGMCGADAKNIISRYKKVRADTWHLDRYQFTSEQLEDME 2139
V PLP WIP+ ++ L+SWARTSGM G AKN IS +KKVRADTW DR F +E+LED+E
Sbjct: 186 VFPLPPWIPKQLSNLSSWARTSGMTGQAAKNTISEFKKVRADTWKFDRASFNTEELEDLE 245
Query: 2140 GVLWRSYYA 2148
GVLWRSYYA
Sbjct: 246 GVLWRSYYA 254
>Hs14724070 [S] KOG1851 Uncharacterized conserved protein
Length = 1729
Score = 63.2 bits (152), Expect = 5e-09
Identities = 120/505 (23%), Positives = 201/505 (39%), Gaps = 72/505 (14%)
Query: 510 KKLNELLSSIETYVHPSNSGYWSD----IIARFIHGFIRMYH-ERYMREKKPE--AKYRE 562
K L L +SI ++ HPSN+G W + ++ R + +R H ERY KKP +
Sbjct: 214 KHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERY---KKPSWLTPVPD 270
Query: 563 ELKLDEDCHEMLVNSFIELLLVGSQSKHSDLANYYISCFGYLLDMKPKNGYKICDRIIVD 622
KL + V I+ +L+ SK L L M+P+ + ++
Sbjct: 271 SHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEA--AQALQNLALMRPE---LVIPPVLER 325
Query: 623 LYDALTDQYVNSEHRLLTSLKQFTRIVRVLIQHELY----RVHITNILSILIDKIDFNDI 678
Y AL + + H+L +L + R L+ + H+ +L + +D ND
Sbjct: 326 TYPAL--ETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTHMLPLLMRALPGVDPNDF 383
Query: 679 SLTSNLMNSIVSISCFIPIEVFVKPEEYLTFESNTIPFIEEHLFFIKQGGSSPDFEYESS 738
S I + S +P+ V L E N + +E L S E+E
Sbjct: 384 SKCMITFQFIATFSTLVPL---VDCSSVLQ-ERNDLTEVEREL-------CSATAEFEDF 432
Query: 739 ILSDAFRA-----STTTFENCLKVYVDKLYQLVDVDIDAGLISKINQTSMIMIQSMDDKM 793
+L R S+T + + +K+ L + ++ GL S S I+ Q +
Sbjct: 433 VLQFMDRCFGLIESSTLEQTREETETEKMTHLESL-VELGLSSTF---STILTQCSKE-- 486
Query: 794 FYYFFGLLEKSFWDNDSFKVKNPLI-ELVSIPLSAAVKRDIRLSARLFRDLDFNIREQIK 852
F L+K F + S + + +V+ AAVK S +LF ++ Q+
Sbjct: 487 --IFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCCSVITQLT 544
Query: 853 GGAGSVRSTTEIQPRDVKLATLLSTLNDVLRQSHESILMFGDELIALLEFIFDNVTNSPL 912
V + E+ D +L L L+++ R +L++ ++L+ +L+ ++T
Sbjct: 545 MN-DDVLNDEEL---DKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTL-HLTCKQG 599
Query: 913 DVINATLLHNALESLTTTEVTDYRLFLQDADVENSEKWGGFQFDRRKYLPEFQQ------ 966
++ LLH+ L S T T+Y GGF +Y P
Sbjct: 600 YTLSCNLLHHLLRSTTLIYPTEY-----------CSVPGGFDKPPSEYFPIKDWGKPGDL 648
Query: 967 ----IEWHQPSSDEVDFAIKLIDHF 987
I+WH PSS+EV FA L+D F
Sbjct: 649 WNLGIQWHVPSSEEVSFAFYLLDSF 673
>At3g13330 [S] KOG1851 Uncharacterized conserved protein
Length = 1709
Score = 55.1 bits (131), Expect = 1e-06
Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 14/168 (8%)
Query: 1974 LTLAEKLFSTQSLVMDHAGKVKILEFVLDKLFCKSFVEVRLKASYVLAGIVHNISYD--- 2030
LT + ++ H K KI + V +KL S +VR A+ VLAG++ D
Sbjct: 1538 LTYLRTFMYRHTFILTHEDKQKIWKTV-EKLLVDS--QVREHAAAVLAGLMKGGDEDFAA 1594
Query: 2031 --TDTLHTLLENFKRQLGSYTFEEKAALSKSNTDIHXXXXXXXXXXEAFPYVSPLPNWIP 2088
D + + +++ K++ ++S +H + PY +P+W+P
Sbjct: 1595 DFRDRSYAEANSIQKRRN----RRKSSSTQSIAGVHGAVLGLVASVLSVPY--DMPSWLP 1648
Query: 2089 ENMALLASWARTSGMCGADAKNIISRYKKVRADTWHLDRYQFTSEQLE 2136
E++ LLA +A + ++ +++ ADTW++ + FT +QLE
Sbjct: 1649 EHVTLLARFAGEPTPIKSTVTKAVAEFRRTHADTWNIQKDSFTEDQLE 1696
>CE05284 [S] KOG1851 Uncharacterized conserved protein
Length = 1908
Score = 54.3 bits (129), Expect = 2e-06
Identities = 55/221 (24%), Positives = 99/221 (43%), Gaps = 31/221 (14%)
Query: 496 LVYSINGRSPQAFFKKLNELLSSIETYVHPSNSGYWSDIIARFIHGFIRMYHERYMREKK 555
LV+ + +S + L +L + +E+++HPSN+G + I + + R RE+
Sbjct: 353 LVFMMGTQSHEKLMSHLRDLFNQVESFMHPSNNGLHTQHIMVLLSKLLSNTILRLKRERS 412
Query: 556 PEAKYR--------EELKLDEDCHEMLVNSFIELLLVGSQSKHSDLANYYISCFGYLLDM 607
+ ++R E ++L + + LVN + L + + +K SC L+
Sbjct: 413 EKTQHRTRTLTPIPEHMRLTQAHLDELVNLMLPCLKLMAFTK---------SC-KELVSP 462
Query: 608 KPKNGYKICDRIIVDL-----YDALTDQYVNSEHRLLTSLKQFTRIVRVLIQHE------ 656
++ +C +II+ + Y AL + + HRLL +L ++ L++ E
Sbjct: 463 AFRSACLLCPKIILPIVLDMVYPAL--ETLVEPHRLLQTLGTLLGVLIPLVKDEPDADGK 520
Query: 657 LYRVHITNILSILIDKIDFNDISLTSNLMNSIVSISCFIPI 697
YR H+ IL+ L+ +D NDIS I I IPI
Sbjct: 521 TYRTHVITILNSLLPGLDCNDISKCMVTYQIIGVIVNMIPI 561
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 124,282,816
Number of Sequences: 60738
Number of extensions: 5435440
Number of successful extensions: 14143
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 14119
Number of HSP's gapped (non-prelim): 12
length of query: 2148
length of database: 30,389,216
effective HSP length: 122
effective length of query: 2026
effective length of database: 22,979,180
effective search space: 46555818680
effective search space used: 46555818680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)