ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3111 check: MH D KOG0600 Cell cycle control, cell division, chromosome partitioning Cdc2-related protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3111 1080245 1081609 455
(455 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL139w [D] KOG0600 Cdc2-related protein kinase 394 e-109
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 305 7e-83
At5g10270 [D] KOG0600 Cdc2-related protein kinase 271 2e-72
At5g64960 [D] KOG0600 Cdc2-related protein kinase 270 4e-72
7296451 [D] KOG0600 Cdc2-related protein kinase 266 6e-71
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 253 4e-67
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 253 4e-67
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 249 8e-66
CE26422 [D] KOG0600 Cdc2-related protein kinase 247 2e-65
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 244 3e-64
At1g09600 [D] KOG0600 Cdc2-related protein kinase 239 5e-63
At1g53050 [D] KOG0600 Cdc2-related protein kinase 238 1e-62
At1g71530 [D] KOG0600 Cdc2-related protein kinase 235 1e-61
At4g10010 [D] KOG0600 Cdc2-related protein kinase 234 2e-61
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 234 3e-61
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 233 3e-61
At5g50860 [D] KOG0600 Cdc2-related protein kinase 231 1e-60
At1g54610 [D] KOG0600 Cdc2-related protein kinase 231 2e-60
At1g33770 [D] KOG0600 Cdc2-related protein kinase 230 3e-60
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 230 4e-60
At3g05050 [D] KOG0600 Cdc2-related protein kinase 225 9e-59
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 223 4e-58
At1g74330 [D] KOG0600 Cdc2-related protein kinase 222 8e-58
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 219 5e-57
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 218 1e-56
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 218 1e-56
At5g44290 [D] KOG0600 Cdc2-related protein kinase 218 1e-56
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 218 1e-56
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 218 1e-56
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 218 2e-56
At1g57700 [D] KOG0600 Cdc2-related protein kinase 218 2e-56
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 4e-56
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 4e-56
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 216 6e-56
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 216 6e-56
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 216 6e-56
At1g03740 [D] KOG0600 Cdc2-related protein kinase 216 6e-56
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 7e-56
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 7e-56
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 7e-56
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 216 7e-56
At1g18670 [D] KOG0600 Cdc2-related protein kinase 216 7e-56
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 1e-55
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 215 1e-55
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 214 2e-55
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 214 2e-55
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 214 3e-55
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 213 5e-55
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 212 8e-55
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 212 1e-54
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 212 1e-54
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 212 1e-54
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 211 2e-54
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 211 2e-54
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 210 3e-54
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 210 4e-54
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 209 7e-54
At4g22940 [D] KOG0600 Cdc2-related protein kinase 208 1e-53
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 207 2e-53
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 207 3e-53
At5g39420 [D] KOG0600 Cdc2-related protein kinase 207 3e-53
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 206 6e-53
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 205 1e-52
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 205 1e-52
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 204 2e-52
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 201 1e-51
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 201 2e-51
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 199 9e-51
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 199 9e-51
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 198 1e-50
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 197 2e-50
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 194 2e-49
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 194 2e-49
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 194 2e-49
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 192 7e-49
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 192 1e-48
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 192 1e-48
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 190 3e-48
YPR161c [D] KOG0600 Cdc2-related protein kinase 190 4e-48
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 190 4e-48
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 190 4e-48
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 189 6e-48
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 187 2e-47
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 187 4e-47
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 186 5e-47
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 183 5e-46
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 183 5e-46
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 179 8e-45
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 176 5e-44
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 176 6e-44
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 171 2e-42
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 170 4e-42
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 169 8e-42
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 168 1e-41
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 168 2e-41
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 167 4e-41
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 167 4e-41
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 166 9e-41
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 164 2e-40
CE06686 [T] KOG0660 Mitogen-activated protein kinase 164 3e-40
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 164 3e-40
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 164 3e-40
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 163 6e-40
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 162 1e-39
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 161 2e-39
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 160 3e-39
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 160 3e-39
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 160 3e-39
YGR040w [T] KOG0660 Mitogen-activated protein kinase 160 4e-39
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 160 4e-39
YBL016w [T] KOG0660 Mitogen-activated protein kinase 160 5e-39
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 160 5e-39
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 159 8e-39
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 159 8e-39
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 158 1e-38
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 158 1e-38
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 158 1e-38
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 158 2e-38
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 157 2e-38
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 157 2e-38
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 157 2e-38
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 157 2e-38
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 157 3e-38
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 157 3e-38
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 157 4e-38
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 156 5e-38
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 156 5e-38
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 155 1e-37
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 154 2e-37
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 154 3e-37
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 152 8e-37
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 152 8e-37
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 152 1e-36
7301110 [T] KOG0660 Mitogen-activated protein kinase 152 1e-36
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 152 1e-36
CE24971 [T] KOG0660 Mitogen-activated protein kinase 152 1e-36
CE01583 [T] KOG0660 Mitogen-activated protein kinase 152 1e-36
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 151 2e-36
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 151 2e-36
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 151 2e-36
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 151 2e-36
YLR113w [T] KOG0660 Mitogen-activated protein kinase 150 3e-36
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 150 3e-36
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 150 4e-36
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 150 4e-36
CE29020 [T] KOG0660 Mitogen-activated protein kinase 150 4e-36
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 150 5e-36
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 149 6e-36
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 149 6e-36
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 149 8e-36
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 149 8e-36
7298087 [T] KOG0660 Mitogen-activated protein kinase 149 1e-35
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 147 3e-35
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 147 3e-35
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 147 3e-35
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 146 5e-35
CE21401 [G] KOG0658 Glycogen synthase kinase-3 146 7e-35
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 145 9e-35
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 145 9e-35
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 144 2e-34
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 144 4e-34
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 144 4e-34
YHR030c [T] KOG0660 Mitogen-activated protein kinase 142 1e-33
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 142 1e-33
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 141 2e-33
7290342 [G] KOG0658 Glycogen synthase kinase-3 141 2e-33
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 141 2e-33
7291043 [T] KOG0660 Mitogen-activated protein kinase 140 4e-33
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 140 5e-33
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 140 5e-33
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 139 7e-33
YPR054w [T] KOG0660 Mitogen-activated protein kinase 139 1e-32
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 139 1e-32
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 139 1e-32
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 139 1e-32
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 138 2e-32
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 137 3e-32
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 137 3e-32
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 137 3e-32
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 137 4e-32
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 135 1e-31
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 135 1e-31
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 135 1e-31
CE17062 [T] KOG0660 Mitogen-activated protein kinase 135 1e-31
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 135 1e-31
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 135 2e-31
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 135 2e-31
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 134 2e-31
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 134 3e-31
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 134 3e-31
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 134 3e-31
CE06762 [T] KOG0660 Mitogen-activated protein kinase 134 4e-31
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 5e-31
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 5e-31
YMR139w [G] KOG0658 Glycogen synthase kinase-3 133 6e-31
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 6e-31
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 133 6e-31
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 133 6e-31
CE08727 [G] KOG0658 Glycogen synthase kinase-3 132 1e-30
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 132 1e-30
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 131 2e-30
CE29318 [T] KOG0660 Mitogen-activated protein kinase 131 2e-30
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 130 3e-30
CE27220 [T] KOG0660 Mitogen-activated protein kinase 130 5e-30
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 129 7e-30
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 129 9e-30
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 128 2e-29
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 128 2e-29
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 127 3e-29
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 127 3e-29
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 127 3e-29
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 8e-29
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 8e-29
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 126 8e-29
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 125 1e-28
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 125 1e-28
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 125 1e-28
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 124 2e-28
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 124 4e-28
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 123 5e-28
YDL079c [G] KOG0658 Glycogen synthase kinase-3 123 6e-28
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 122 1e-27
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 121 2e-27
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 119 9e-27
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 119 1e-26
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 119 1e-26
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 118 2e-26
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 117 4e-26
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 116 8e-26
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 115 1e-25
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 115 1e-25
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 115 1e-25
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 115 2e-25
At3g29160 [T] KOG0583 Serine/threonine protein kinase 115 2e-25
YKL161c [T] KOG0660 Mitogen-activated protein kinase 114 2e-25
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 114 3e-25
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 114 4e-25
At5g39440 [T] KOG0583 Serine/threonine protein kinase 114 4e-25
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 113 7e-25
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 112 9e-25
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 112 1e-24
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 112 1e-24
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 112 1e-24
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 112 1e-24
7302464 [R] KOG0586 Serine/threonine protein kinase 112 1e-24
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 111 2e-24
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 111 2e-24
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 111 2e-24
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 111 3e-24
At4g14580 [T] KOG0583 Serine/threonine protein kinase 110 6e-24
YNL307c [G] KOG0658 Glycogen synthase kinase-3 109 7e-24
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 109 7e-24
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 109 1e-23
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 108 1e-23
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 108 2e-23
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 108 2e-23
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 108 2e-23
CE05866 [G] KOG0658 Glycogen synthase kinase-3 107 3e-23
CE01612 [G] KOG0658 Glycogen synthase kinase-3 107 3e-23
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 107 3e-23
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 107 4e-23
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 106 6e-23
CE27768 [R] KOG0586 Serine/threonine protein kinase 106 6e-23
CE05377 [G] KOG0658 Glycogen synthase kinase-3 106 6e-23
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 106 8e-23
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 106 8e-23
CE23838 [R] KOG0586 Serine/threonine protein kinase 105 1e-22
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 105 1e-22
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 105 1e-22
At4g30960 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
At2g26980 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 104 2e-22
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 104 2e-22
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 104 2e-22
At3g01090 [T] KOG0583 Serine/threonine protein kinase 104 2e-22
YDR477w [T] KOG0583 Serine/threonine protein kinase 103 4e-22
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 103 4e-22
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 103 4e-22
At5g57630 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
At5g45820 [T] KOG0583 Serine/threonine protein kinase 103 4e-22
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 103 4e-22
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 103 4e-22
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 103 4e-22
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 103 5e-22
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 103 7e-22
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 103 7e-22
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 103 7e-22
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 103 7e-22
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 102 9e-22
CE20405 [G] KOG0658 Glycogen synthase kinase-3 102 9e-22
At4g18700 [T] KOG0583 Serine/threonine protein kinase 102 9e-22
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 102 9e-22
CE09532 [G] KOG0658 Glycogen synthase kinase-3 102 1e-21
At2g38490 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
7299438 [R] KOG0586 Serine/threonine protein kinase 102 1e-21
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 102 2e-21
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 102 2e-21
At2g30360 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 101 2e-21
At5g25110 [T] KOG0583 Serine/threonine protein kinase 101 2e-21
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 101 2e-21
7298004 [G] KOG0658 Glycogen synthase kinase-3 101 2e-21
7295638 [T] KOG0603 Ribosomal protein S6 kinase 101 2e-21
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 101 3e-21
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 101 3e-21
YPL209c [D] KOG0580 Serine/threonine protein kinase 100 3e-21
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 3e-21
At3g17510 [T] KOG0583 Serine/threonine protein kinase 100 3e-21
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 100 3e-21
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 100 4e-21
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 100 4e-21
CE27177 [T] KOG4279 Serine/threonine protein kinase 100 4e-21
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 100 4e-21
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 100 6e-21
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 100 6e-21
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 100 8e-21
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 100 8e-21
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 100 8e-21
At5g45810 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
At3g23000 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
At1g29230 [T] KOG0583 Serine/threonine protein kinase 100 8e-21
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 99 1e-20
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 99 1e-20
CE28674 [T] KOG0201 Serine/threonine protein kinase 99 1e-20
CE28643 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
CE07458 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
At5g01810 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 99 1e-20
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 99 1e-20
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 99 1e-20
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 99 1e-20
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 99 1e-20
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 1e-20
At2g34180 [T] KOG0583 Serine/threonine protein kinase 99 1e-20
7300559 [T] KOG4279 Serine/threonine protein kinase 99 1e-20
YHR102w [T] KOG0201 Serine/threonine protein kinase 99 2e-20
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 99 2e-20
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 99 2e-20
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 99 2e-20
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 98 3e-20
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 98 3e-20
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 97 4e-20
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 97 4e-20
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 97 4e-20
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 97 4e-20
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 97 4e-20
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 97 4e-20
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 97 4e-20
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 4e-20
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 97 4e-20
CE07510 [T] KOG0201 Serine/threonine protein kinase 97 4e-20
7299437 [R] KOG0586 Serine/threonine protein kinase 97 4e-20
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 97 5e-20
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 97 5e-20
CE01554 [T] KOG0986 G protein-coupled receptor kinase 97 5e-20
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 97 5e-20
7290150 [T] KOG0583 Serine/threonine protein kinase 97 5e-20
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 97 6e-20
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 97 6e-20
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 96 8e-20
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 96 8e-20
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 96 8e-20
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 96 8e-20
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 96 8e-20
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 96 1e-19
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 96 1e-19
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 96 1e-19
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
CE00847 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
At2g45490 [D] KOG0580 Serine/threonine protein kinase 96 1e-19
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 96 1e-19
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 96 1e-19
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 1e-19
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 96 1e-19
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 96 1e-19
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 96 1e-19
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 96 1e-19
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 96 1e-19
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 96 1e-19
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 96 1e-19
At4g24400 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 96 1e-19
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 96 1e-19
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 96 1e-19
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 95 2e-19
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 95 2e-19
At5g10930 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 95 2e-19
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 95 2e-19
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 95 2e-19
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 95 2e-19
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 94 3e-19
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 94 3e-19
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 94 3e-19
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 94 3e-19
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 94 4e-19
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 94 4e-19
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 94 4e-19
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 94 4e-19
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 94 4e-19
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 94 5e-19
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 94 5e-19
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 94 5e-19
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 94 5e-19
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 94 5e-19
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 94 5e-19
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 94 5e-19
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 93 7e-19
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 93 7e-19
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 93 7e-19
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 93 7e-19
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 93 7e-19
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 93 7e-19
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 93 7e-19
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 93 7e-19
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 93 7e-19
7299793 [T] KOG0583 Serine/threonine protein kinase 93 7e-19
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 93 9e-19
At5g01820 [T] KOG0583 Serine/threonine protein kinase 93 9e-19
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 92 1e-18
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 92 1e-18
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 92 1e-18
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 92 1e-18
CE29092 [T] KOG0694 Serine/threonine protein kinase 92 1e-18
At2g25090 [T] KOG0583 Serine/threonine protein kinase 92 1e-18
At1g54510 [R] KOG0589 Serine/threonine protein kinase 92 1e-18
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 92 1e-18
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 92 2e-18
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 92 2e-18
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 92 2e-18
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 92 2e-18
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 92 2e-18
7290249 [R] KOG0586 Serine/threonine protein kinase 92 2e-18
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 92 2e-18
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 92 2e-18
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 92 2e-18
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 91 3e-18
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 91 3e-18
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 91 3e-18
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 91 3e-18
At1g30270 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 91 3e-18
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 91 3e-18
YOL128c [G] KOG0658 Glycogen synthase kinase-3 91 4e-18
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 91 4e-18
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 91 4e-18
At3g06230 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 91 4e-18
At1g53165 [T] KOG0201 Serine/threonine protein kinase 91 4e-18
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 91 4e-18
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 91 5e-18
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 91 5e-18
CE27410 [T] KOG0583 Serine/threonine protein kinase 91 5e-18
7300106 [T] KOG0690 Serine/threonine protein kinase 91 5e-18
YDR507c [D] KOG0588 Serine/threonine protein kinase 90 6e-18
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 90 6e-18
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 90 6e-18
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 90 6e-18
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 90 6e-18
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 90 6e-18
At1g48260 [T] KOG0583 Serine/threonine protein kinase 90 6e-18
7300224 [T] KOG0201 Serine/threonine protein kinase 90 6e-18
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 90 8e-18
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 90 8e-18
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 89 1e-17
YCL024w [T] KOG0583 Serine/threonine protein kinase 89 1e-17
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 89 1e-17
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 89 1e-17
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 89 1e-17
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 89 1e-17
CE24761 [D] KOG0580 Serine/threonine protein kinase 89 1e-17
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 89 1e-17
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 89 1e-17
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 89 1e-17
At5g35410 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
YPL150w [T] KOG0583 Serine/threonine protein kinase 89 1e-17
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 89 1e-17
Hs5579478 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 89 1e-17
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 89 1e-17
At5g28290 [R] KOG0589 Serine/threonine protein kinase 89 1e-17
At3g15220 [T] KOG0201 Serine/threonine protein kinase 89 1e-17
7301734 [T] KOG0694 Serine/threonine protein kinase 89 1e-17
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 89 2e-17
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 89 2e-17
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 88 2e-17
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 88 2e-17
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 394 bits (1011), Expect = e-109
Identities = 219/442 (49%), Positives = 284/442 (63%), Gaps = 21/442 (4%)
Query: 8 HRPNTGVSMSQPKIFRKKRQESRYHGGS---QSRYQPNRPNNHHNTAGNVNVNRSLGKRN 64
HR N+ K R SRY+ S SRYQ +R NN N N +S+ +
Sbjct: 57 HRVNSNDQPGHTKS-RGNNNLSRYNDTSFQTSSRYQGSRYNN--NNTSYENRPKSIKRDE 113
Query: 65 PRGKF--NRPSNGPETSGSRFEGHGS----IPRGPRAMGSSAESAGDSHSRNIFGKK-PL 117
+ +F + P SR+ + I G A S + R++ KK P+
Sbjct: 114 TKAEFLSHLPKGPKSVEKSRYNNSSNTSNDIKNGYHA--SKYYNHKGQEGRSVIAKKVPV 171
Query: 118 ALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREI 177
++++ Q S + + QVGEGTYGKVYKA+N +T KL+ALK+LRL+ ER+GFPITSIREI
Sbjct: 172 SVLTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREI 231
Query: 178 KLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLF 237
KLLQ +HPN+S I EI+V + T+ M F+Y +NDLSG+L++K +Q S S KHL KQL
Sbjct: 232 KLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLL 291
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRP 297
+G++YLH +I+HRD+KGSN+LIDN+GNLKITDFGLA+K+ +S A TNRVITLWYRP
Sbjct: 292 LGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKM---NSRADYTNRVITLWYRP 348
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
PELLLG T+Y EVD WGCGCLLVELF AIF GSNE++Q + I IMG+PT+ WP +
Sbjct: 349 PELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTL 408
Query: 358 LDMPWWFMLVPQISKTYKNVFFDEFSKV--PQDALDLASKLLRYDQDTRFTTTEALQHHY 415
DMPW+FM++PQ + Y N F ++F V L LA LL YDQ RF+ TEALQ Y
Sbjct: 409 YDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDY 468
Query: 416 FTNEPKPQPLLLGPEFKGSHEY 437
F EPKP+PL+L HEY
Sbjct: 469 FKEEPKPEPLVL-DGLVSCHEY 489
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 305 bits (782), Expect = 7e-83
Identities = 177/444 (39%), Positives = 263/444 (58%), Gaps = 29/444 (6%)
Query: 11 NTGVSMSQPKIFRKK------RQESRYHGGSQSRYQPNRPNN-----HHNTAGNVNVNRS 59
N S Q FR+ + S ++G SR + P H T+ + S
Sbjct: 153 NRNDSKRQASSFRRSPPSSVHMKPSAFNGRKVSRRPSSSPPPIPSIPHETTSSDTQKKSS 212
Query: 60 LGK---RNPRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKP 116
+ N GKF+ + P SRF+ + P + +A +S +
Sbjct: 213 VSSGFPENKHGKFH--FHIPNERRSRFD------QPPSKRMALTSTARESVPAPLPSPPS 264
Query: 117 LALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIRE 176
+ ++ K +++ + Q+GEGTYGKVYKA N TG L+ALKR+RLEQE+DGFPIT++RE
Sbjct: 265 GPIYTYTYPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPITTVRE 324
Query: 177 IKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQL 236
+K+LQ+L H NI + EI+V +K+++ M F+YM++DL+G+L++ + F+ NIKHL KQ+
Sbjct: 325 VKILQRLRHKNIVRLLEIMV-EKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQI 383
Query: 237 FVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYR 296
F L YLH + ++HRDIKGSN+L++N G+LK DFGLA+ T S A+ TNRVITLW+R
Sbjct: 384 FEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTS-SKSANYTNRVITLWFR 442
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PPELLLG T Y VD W GC+++ELF G F G +E+ Q + I +MG+P + WP+
Sbjct: 443 PPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQLEVIYDMMGTPDVHSWPE 502
Query: 357 MLDMPWWFMLVPQISKTYKNVFFDEFSKV-PQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+ ++PW+ +L P K K+ F + F ++ A+DL KLL + R + E L H Y
Sbjct: 503 VKNLPWYELLKPVEEK--KSRFVETFKEILSPAAIDLCQKLLALNPFCRPSAHETLMHEY 560
Query: 416 FTNE-PKPQPLLLGPEFKGS-HEY 437
FT+E P P+P ++ +GS HE+
Sbjct: 561 FTSESPPPEPAVILKNMQGSWHEW 584
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 271 bits (692), Expect = 2e-72
Identities = 141/324 (43%), Positives = 196/324 (59%), Gaps = 18/324 (5%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ L Q+GEGTYG+VY A+ + TG+++ALK++R++ ER+GFPIT+IREIK+L++L+H N+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 189 SLIHEIIVSD---------------KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLM 233
+ EI+ S K I M F+YM++DL+G+ ++F+ IK M
Sbjct: 86 IQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYM 145
Query: 234 KQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITL 293
KQL GL Y H Q++HRDIKGSNLLIDN GNLK+ DFGLA+ + + TNRVITL
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSH-DHTGNLTNRVITL 204
Query: 294 WYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQ 353
WYRPPELLLGAT Y +D W GC+ EL I PG NE +Q +I + GSP +
Sbjct: 205 WYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQLNKIFELCGSPDEKL 264
Query: 354 WPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQH 413
WP + MPW+ P ++ K + F + AL+L K+L D R + +AL
Sbjct: 265 WPGVSKMPWFNNFKP--ARPLKRRVREFFRHFDRHALELLEKMLVLDPAQRISAKDALDA 322
Query: 414 HYFTNEPKPQPLLLGPEFKGSHEY 437
YF +P P P ++ SHE+
Sbjct: 323 EYFWTDPLPCDPKSLPTYESSHEF 346
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 270 bits (689), Expect = 4e-72
Identities = 140/324 (43%), Positives = 195/324 (59%), Gaps = 18/324 (5%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ L Q+GEGTYG+VY A+ + TG+++ALK++R++ ER+GFPIT+IREIK+L++L+H N+
Sbjct: 26 FEKLEQIGEGTYGQVYMAKEIKTGEIVALKKIRMDNEREGFPITAIREIKILKKLHHENV 85
Query: 189 SLIHEIIVSD---------------KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLM 233
+ EI+ S K I M F+YM++DL+G+ ++F+ IK M
Sbjct: 86 IHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLRFTVPQIKCYM 145
Query: 234 KQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITL 293
KQL GL Y H Q++HRDIKGSNLLIDN GNLK+ DFGLA+ + + TNRVITL
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSH-DHTGNLTNRVITL 204
Query: 294 WYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQ 353
WYRPPELLLGAT Y +D W GC+ EL G I PG E +Q +I + GSP
Sbjct: 205 WYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENEQLNKIYELCGSPDESN 264
Query: 354 WPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQH 413
WP + MPW+ + + S+ K + + + AL+L K+L D R +AL
Sbjct: 265 WPGVSKMPWYNQM--KSSRPLKRRVREIYRHFDRHALELLEKMLVLDPSQRICAKDALDA 322
Query: 414 HYFTNEPKPQPLLLGPEFKGSHEY 437
YF +P P P ++ SHE+
Sbjct: 323 EYFWTDPLPCDPKSLPTYESSHEF 346
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 266 bits (679), Expect = 6e-71
Identities = 136/318 (42%), Positives = 195/318 (60%), Gaps = 12/318 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ +AQ+GEGTYG+VYKA + HT ++ALK++RLE E++GFPIT++REIK+L+QLNH NI
Sbjct: 804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNI 863
Query: 189 SLIHEIIVS---------DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
+HEI+ DK + + F+YM++DL G+L + F++ N +MKQL G
Sbjct: 864 VNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDG 923
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L Y H++ +HRDIK SN+L++NRG +K+ DFGLA+ TN+VITLWYRPPE
Sbjct: 924 LNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPE 983
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLLG Y +D W CGC+L ELF +F + E+ Q + I I GSP WP ++
Sbjct: 984 LLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIK 1043
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN- 418
+P + L + KT++ ++F +P ALDL K+L D D R T +AL+ +
Sbjct: 1044 LPLFHTL--KQKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKI 1101
Query: 419 EPKPQPLLLGPEFKGSHE 436
P P P ++ HE
Sbjct: 1102 NPDEMPTPQLPTWQDCHE 1119
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 253 bits (646), Expect = 4e-67
Identities = 134/318 (42%), Positives = 195/318 (61%), Gaps = 13/318 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F + +GEGTYG+VYKA + TG+++ALK++RL+ E++GFPIT+IREIK+L+QL H +I
Sbjct: 705 FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSI 764
Query: 189 SLIHEIIVS---------DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
+ EI+ DK + F+YM++DL G+L + F++++IK M+QL G
Sbjct: 765 INMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEG 824
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L Y H++ +HRDIK SN+L++NRG +K+ DFGLA+ + S TN+VITLWYRPPE
Sbjct: 825 LDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEES-RPYTNKVITLWYRPPE 883
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLLG Y +D W CGC+L ELF IF + E+ Q + I I GSP WP ++
Sbjct: 884 LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIK 943
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN- 418
+P++ + P+ K Y+ +EF +P ALDL +L D R T +ALQ + +
Sbjct: 944 LPYFNTMKPK--KQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDV 1001
Query: 419 EPKPQPLLLGPEFKGSHE 436
EP P P ++ HE
Sbjct: 1002 EPSKMPPPDLPLWQDCHE 1019
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 253 bits (646), Expect = 4e-67
Identities = 134/318 (42%), Positives = 195/318 (61%), Gaps = 13/318 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F + +GEGTYG+VYKA + TG+++ALK++RL+ E++GFPIT+IREIK+L+QL H +I
Sbjct: 705 FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSI 764
Query: 189 SLIHEIIVS---------DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
+ EI+ DK + F+YM++DL G+L + F++++IK M+QL G
Sbjct: 765 INMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEG 824
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L Y H++ +HRDIK SN+L++NRG +K+ DFGLA+ + S TN+VITLWYRPPE
Sbjct: 825 LDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEES-RPYTNKVITLWYRPPE 883
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLLG Y +D W CGC+L ELF IF + E+ Q + I I GSP WP ++
Sbjct: 884 LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIK 943
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN- 418
+P++ + P+ K Y+ +EF +P ALDL +L D R T +ALQ + +
Sbjct: 944 LPYFNTMKPK--KQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDV 1001
Query: 419 EPKPQPLLLGPEFKGSHE 436
EP P P ++ HE
Sbjct: 1002 EPSKMPPPDLPLWQDCHE 1019
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 249 bits (635), Expect = 8e-66
Identities = 128/296 (43%), Positives = 185/296 (62%), Gaps = 12/296 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F + +GEGTYG+VYKA + TG+L+ALK++RL+ E++GFPIT+IREIK+L+QL H ++
Sbjct: 727 FDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSV 786
Query: 189 SLIHEIIVS---------DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
+ EI+ DK + F+YM++DL G+L + FS+ +IK MKQL G
Sbjct: 787 VNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEG 846
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L+Y H++ +HRDIK SN+L++N G +K+ DFGLA +L + TN+VITLWYRPPE
Sbjct: 847 LEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLA-RLYNSEESRPYTNKVITLWYRPPE 905
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLLG Y +D W CGC+L ELF IF + E+ Q + I + GSP WP ++
Sbjct: 906 LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIK 965
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+P++ + P+ K Y+ +EFS +P ALDL +L D R T + LQ +
Sbjct: 966 LPYFNTMKPK--KQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDF 1019
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 247 bits (631), Expect = 2e-65
Identities = 136/318 (42%), Positives = 196/318 (60%), Gaps = 18/318 (5%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L Q+GEGTYG+VYKA N TG+ +ALKR+RLE E++GFPIT+IREIK+L+QL+H NI +
Sbjct: 314 LDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRL 373
Query: 192 HEIIVSD---------KNTISMGFQYMENDLSGMLMDKS-IQFSDSNIKHLMKQLFVGLQ 241
+I++ D + + F+Y+++DL G+L K + F+ I L KQL GL
Sbjct: 374 MDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLA 433
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
Y+H +HRDIK SN+L++N+G LKI D GLA+ S TNRVITLWYRPPELL
Sbjct: 434 YIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKES--RLYTNRVITLWYRPPELL 491
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
LG Y +D W GC+L ELF +F G+NE Q + I + GSP ++ WP++ ++
Sbjct: 492 LGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELV 551
Query: 362 WWFMLVPQISKTYKNVFFDEFSKV-PQDALDLASKLLRYDQDTRFTTTEALQHHYFTN-- 418
W ++ +TY+ +EF + P++A+DL K+L + + R + EAL H + +
Sbjct: 552 GWNTF--RMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWIRSLE 609
Query: 419 EPKPQPLLLGPEFKGSHE 436
QPL L P+ + HE
Sbjct: 610 HTTVQPLKL-PQHQDCHE 626
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 244 bits (622), Expect = 3e-64
Identities = 127/313 (40%), Positives = 187/313 (59%), Gaps = 8/313 (2%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ L ++ EGTYG VY+A++ TG+++ALK++++E+ER+GFP+TS+REI +L +HP+I
Sbjct: 406 FERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPSI 465
Query: 189 SLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ E++V S ++I M +YME+DL ++ +FS S +K LM QL G++YLH
Sbjct: 466 VDVKEVVVGSSLDSIFMVMEYMEHDLKALMETMKQRFSQSEVKCLMLQLLEGVKYLHDNW 525
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
++HRD+K SNLL++NRG LKI DFGLA++ P T+ V+TLWYR PELLLGA Y
Sbjct: 526 VLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKP--YTHLVVTLWYRAPELLLGAKQY 583
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC++ EL A +F G E DQ +I I+G+P WP +P +
Sbjct: 584 STAIDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVNF 643
Query: 368 PQ-----ISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
+ + K + F + DL +KLL YD + R T EAL+H +F P P
Sbjct: 644 VKHQYNLLRKKFPATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFREVPLP 703
Query: 423 QPLLLGPEFKGSH 435
+ P F H
Sbjct: 704 KSKDFMPTFPAQH 716
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 239 bits (611), Expect = 5e-63
Identities = 128/294 (43%), Positives = 178/294 (60%), Gaps = 5/294 (1%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SF+ L ++G+GTY VYKA ++ T +L+ALK++R REI +L++L+HPN
Sbjct: 162 SFEKLEKIGQGTYSSVYKARDLETNQLVALKKVRFANMDPDSVRFMAREIIILRRLDHPN 221
Query: 188 ISLIHEIIVSD-KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ + +I S ++ + F+YME+DL+G+ I FS++ IK MKQL GL++ H +
Sbjct: 222 VMKLEGLITSRVSGSMYLIFEYMEHDLAGLASTPGINFSEAQIKCYMKQLLHGLEHCHSR 281
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRDIKGSNLL+D+ NLKI DFGLA T+RV+TLWYRPPELLLG+TD
Sbjct: 282 GVLHRDIKGSNLLLDHNNNLKIGDFGLAN-FYQGHQKQPLTSRVVTLWYRPPELLLGSTD 340
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC+L ELF G I PG EV+Q +I + GSP+ E W K+ +P +
Sbjct: 341 YGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKLCGSPSEEYW-KISKLPHATIF 399
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
PQ + YK + F +P AL L LL + D R TT AL+ +FT P
Sbjct: 400 KPQ--QPYKRCVAETFKSLPSSALALVEVLLAVEPDARGTTASALESEFFTTSP 451
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 238 bits (607), Expect = 1e-62
Identities = 130/310 (41%), Positives = 189/310 (60%), Gaps = 5/310 (1%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SF+ L ++G+GTY VY+A ++ K++ALK++R + REI++L++L+HPN
Sbjct: 133 SFEKLDKIGQGTYSNVYRARDLDQKKIVALKKVRFDNLEPESVRFMAREIQILRRLDHPN 192
Query: 188 ISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
I + ++ S + ++ + F+YME+DL+G+ +I+FS+S +K ++QL GL + H +
Sbjct: 193 IIKLEGLVTSRMSCSLYLVFEYMEHDLAGLASHPAIKFSESQVKCYLQQLLHGLDHCHSR 252
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRDIKGSNLLIDN G LKI DFGLA D T+RV+TLWYRPPELLLGAT
Sbjct: 253 GVLHRDIKGSNLLIDNSGVLKIADFGLAS-FFDPRQTQPLTSRVVTLWYRPPELLLGATR 311
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC+L EL+AG I PG EV+Q +I + GSPT + W K +P +
Sbjct: 312 YGAAVDLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDYWVKS-RLPHATIF 370
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPLL 426
P ++ YK + + F + PQ AL L LL + D R T T AL+ +F+ P P
Sbjct: 371 KP--TQPYKRLVGETFKEFPQPALALLETLLSVNPDDRGTATAALKSEFFSTRPLPCDPS 428
Query: 427 LGPEFKGSHE 436
P++ S E
Sbjct: 429 SLPKYPPSKE 438
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 235 bits (599), Expect = 1e-61
Identities = 126/296 (42%), Positives = 181/296 (60%), Gaps = 5/296 (1%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SF+ L ++G+GTY VYKA ++ TGK++A+K++R REI +L++L+HPN
Sbjct: 146 SFEKLDKIGQGTYSSVYKARDLETGKIVAMKKVRFVNMDPESVRFMAREILILRKLDHPN 205
Query: 188 ISLIHEIIVSD-KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ + ++ S ++ + F+YME+DL+G+ I+FS+ IK M+QLF GL++ H++
Sbjct: 206 VMKLEGLVTSRLSGSLYLVFEYMEHDLAGLAATPGIKFSEPQIKCYMQQLFRGLEHCHRR 265
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
I+HRDIKGSNLLI+N G LKI DFGLA T+RV+TLWYR PELLLGAT+
Sbjct: 266 GILHRDIKGSNLLINNEGVLKIGDFGLANFYRG-DGDLQLTSRVVTLWYRAPELLLGATE 324
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y +D W GC+L ELFAG I PG EV+Q +I + GSP+ + W + +P
Sbjct: 325 YGPAIDLWSAGCILTELFAGKPIMPGRTEVEQMHKIFKLCGSPSEDYW-RRATLPLATSF 383
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
P S YK V + F+ P AL L +KLL + + R + L+ +FT EP P
Sbjct: 384 KP--SHPYKPVLAETFNHFPSSALMLINKLLAIEPEKRGSAASTLRSEFFTTEPLP 437
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 234 bits (598), Expect = 2e-61
Identities = 127/310 (40%), Positives = 184/310 (58%), Gaps = 5/310 (1%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SF+ L ++G+GTY VY+A ++ TGK++A+K++R REI +L++L+HPN
Sbjct: 155 SFEKLDKIGQGTYSSVYRARDLETGKMVAMKKVRFVNMDPESVRFMAREINILRKLDHPN 214
Query: 188 ISLIHEIIVSD-KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ + ++ S ++ + F+YME+DLSG+ + ++F++S IK MKQL GL++ H +
Sbjct: 215 VMKLECLVTSKLSGSLYLVFEYMEHDLSGLALRPGVKFTESQIKCYMKQLLSGLEHCHSR 274
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
I+HRDIKG NLL++N G LKI DFGLA + T+RV+TLWYR PELLLGAT+
Sbjct: 275 GILHRDIKGPNLLVNNDGVLKIGDFGLAN-IYHPEQDQPLTSRVVTLWYRAPELLLGATE 333
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y +D W GC+L ELF G I PG EV+Q +I GSP+ + W K +P
Sbjct: 334 YGPGIDLWSVGCILTELFLGKPIMPGRTEVEQMHKIFKFCGSPSDDYWQK-TKLPLATSF 392
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPLL 426
PQ + YK V + F +P AL L KLL + R T + L +FT EP P +
Sbjct: 393 KPQ--QPYKRVLLETFKNLPPSALALVDKLLSLEPAKRGTASSTLSSKFFTMEPLPCNVS 450
Query: 427 LGPEFKGSHE 436
P++ S E
Sbjct: 451 SLPKYPPSKE 460
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 234 bits (596), Expect = 3e-61
Identities = 131/329 (39%), Positives = 195/329 (58%), Gaps = 15/329 (4%)
Query: 122 FQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQ 181
F D S ++ LA++G+GT+G+V+KA + TG+ +ALK++ +E E++GFPIT++REIK+LQ
Sbjct: 12 FCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQ 71
Query: 182 QLNHPNISLIHEIIVSD-------KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMK 234
L H N+ + EI + K +I + F + E+DL+G+L + ++F+ S IK +M+
Sbjct: 72 LLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQ 131
Query: 235 QLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAK--KLTDVSSPASNTNRVIT 292
L GL Y+H+ +I+HRD+K +N+LI G LK+ DFGLA+ L S P TNRV+T
Sbjct: 132 MLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVT 191
Query: 293 LWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLE 352
LWYRPPELLLG DY +D WG GC++ E++ + I G+ E Q I + GS T E
Sbjct: 192 LWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPE 251
Query: 353 QWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQD--ALDLASKLLRYDQDTRFTTTEA 410
WP + + + L ++ K K D +D ALDL KLL D R + +A
Sbjct: 252 VWPNVDNYELYEKL--ELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDA 309
Query: 411 LQHHYFTNEPKPQPL--LLGPEFKGSHEY 437
L H +F ++P P L +L EY
Sbjct: 310 LNHDFFWSDPMPSDLKGMLSTHLTSMFEY 338
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 233 bits (595), Expect = 3e-61
Identities = 131/331 (39%), Positives = 190/331 (56%), Gaps = 24/331 (7%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
+ + + ++GEGT+G+VYK++ GK+ ALKR+ + E++GFPIT+IREIK+L+ + H
Sbjct: 34 TDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKHE 93
Query: 187 NISLIHEIIV--SDKN-----TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
NI + ++ V +DK +I M YM++DLSG+L + S++F++ IK MKQLF G
Sbjct: 94 NIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAG 153
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-----------TN 288
+YLH Q I+HRD+K +NLLIDN G LKI DFGLA+ +T+ S N T
Sbjct: 154 TKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYTG 213
Query: 289 RVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGS 348
V+T WYR PELLLG Y +D W GC++ E++ G I GS+++DQ +I + GS
Sbjct: 214 CVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGS 273
Query: 349 PTLEQWPKMLDMPW--WFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFT 406
PT P +P P +T + FF F K + L +L + D R +
Sbjct: 274 PTQATMPNWEKLPGCEGVRSFPSHPRTLETAFF-TFGK---EMTSLCGAILTLNPDERLS 329
Query: 407 TTEALQHHYFTNEPKPQPLLLGPEFKGSHEY 437
+ AL+H YFT P P + SHEY
Sbjct: 330 ASMALEHEYFTTPPYPANPSELQSYSASHEY 360
>At5g50860 [D] KOG0600 Cdc2-related protein kinase
Length = 580
Score = 231 bits (590), Expect = 1e-60
Identities = 126/311 (40%), Positives = 185/311 (58%), Gaps = 5/311 (1%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
++++ L ++G+GTY VYKA+++ +GK++ALK++R + REI +L++LNHP
Sbjct: 112 TTYEKLEKIGQGTYSNVYKAKDLLSGKIVALKKVRFDNLEAESVKFMAREILVLRRLNHP 171
Query: 187 NISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
N+ + ++ S + ++ + F+YME+DLSG+ + ++F +K MKQL GL++ H
Sbjct: 172 NVIKLQGLVTSRVSCSLYLVFEYMEHDLSGLAATQGLKFDLPQVKCFMKQLLSGLEHCHS 231
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
+ ++HRDIKGSNLLIDN G LKI DFGLA D + T+RV+TLWYRPPELLLGAT
Sbjct: 232 RGVLHRDIKGSNLLIDNDGILKIADFGLAT-FYDPKQKQTMTSRVVTLWYRPPELLLGAT 290
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y VD W GC++ EL AG + PG EV+Q +I + GSP+ W K +P +
Sbjct: 291 SYGTGVDLWSAGCIMAELLAGKPVMPGRTEVEQLHKIFKLCGSPSDSYW-KKYRLPNATL 349
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
PQ YK + F+ ++ L LL D R T+T AL +FT EP P
Sbjct: 350 FKPQ--HPYKRCVAEAFNGFTPSSVHLVETLLTIDPADRGTSTSALNSEFFTTEPLPCDP 407
Query: 426 LLGPEFKGSHE 436
P++ S E
Sbjct: 408 SSLPKYPPSKE 418
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 231 bits (589), Expect = 2e-60
Identities = 120/294 (40%), Positives = 184/294 (61%), Gaps = 5/294 (1%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+F+ + ++G+GTY VYKA+++ TGK++ALK++R + REI +L++L+HPN
Sbjct: 117 TFEKIDKIGQGTYSNVYKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLDHPN 176
Query: 188 ISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ + ++ S + ++ + FQYM++DL+G+ ++FS+S +K LM+QL GL++ H +
Sbjct: 177 VVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVKFSESEVKCLMRQLISGLEHCHSR 236
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRDIKGSNLLID+ G LKI DFGLA + D + T+RV+TLWYR PELLLGATD
Sbjct: 237 GVLHRDIKGSNLLIDDGGVLKIADFGLAT-IFDPNHKRPMTSRVVTLWYRAPELLLGATD 295
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y +D W GC+L EL AG I PG EV+Q +I + GSP+ + W K +
Sbjct: 296 YGVGIDLWSAGCILAELLAGRPIMPGRTEVEQLHKIYKLCGSPSEDYWKK---GKFTHGA 352
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+ + + YK + F P +L L LL + + R T + AL+ +FT+EP
Sbjct: 353 IYKPREPYKRSIRETFKDFPPSSLPLIDALLSIEPEDRQTASAALKSEFFTSEP 406
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 230 bits (587), Expect = 3e-60
Identities = 126/311 (40%), Positives = 183/311 (58%), Gaps = 7/311 (2%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SF+ L ++G+GTY VYKA ++ TGK++A+K++R REI +L++L+HPN
Sbjct: 140 SFEKLDKIGQGTYSIVYKARDLETGKIVAMKKVRFANMDPESVRFMAREINILRKLDHPN 199
Query: 188 ISLIHEIIVSD-KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ + ++ S ++ + F+YME+DLSG+ + ++F++ IK MKQL GL++ H +
Sbjct: 200 VMKLQCLVTSKLSGSLHLVFEYMEHDLSGLALRPGVKFTEPQIKCFMKQLLCGLEHCHSR 259
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I+HRDIKGSNLL++N G LKI DFGLA D P T+RV+TLWYR PELLLG+T
Sbjct: 260 GILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPL--TSRVVTLWYRAPELLLGST 317
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
+Y +D W GC+L ELF I PG EV+Q +I + GSP+ E W P
Sbjct: 318 EYGPAIDLWSVGCILAELFVCKPIMPGRTEVEQMHKIFKLCGSPSEEFW-NTTKFPQATS 376
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
PQ YK V + F + +LDL KLL + + R + + L +FT EP P +
Sbjct: 377 YKPQ--HPYKRVLLETFKNLSSSSLDLLDKLLSVEPEKRCSASSTLLSEFFTTEPLPCHI 434
Query: 426 LLGPEFKGSHE 436
P++ S E
Sbjct: 435 SSLPKYPPSKE 445
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 230 bits (586), Expect = 4e-60
Identities = 123/308 (39%), Positives = 182/308 (58%), Gaps = 13/308 (4%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERD----GFPITSIREIKLLQQ 182
+ FQ L ++ EGTYG VYKA + T +++ALK+++++++R GFP+TS+REI +L
Sbjct: 295 NEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLS 354
Query: 183 LNHPNISLIHEIIVSDKNT--ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGL 240
NHP I + E++V KN + M +++E+DL G++ + FS S +K LM QL GL
Sbjct: 355 CNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLDGL 414
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+YLH I+HRD+K SNLL++N G LKI DFG+A++ P T VIT WYRPPEL
Sbjct: 415 KYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPY--TQMVITQWYRPPEL 472
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC++ EL + +FPG +E+DQ Q+I +++G+P WP
Sbjct: 473 LLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFSSF 532
Query: 361 PWWFMLVP-----QISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
P P + K + + F + + DL + LL D + R T +AL H +
Sbjct: 533 PNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNHGW 592
Query: 416 FTNEPKPQ 423
F P P+
Sbjct: 593 FHEVPLPK 600
>At3g05050 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 225 bits (574), Expect = 9e-59
Identities = 126/299 (42%), Positives = 181/299 (60%), Gaps = 12/299 (4%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLE-QERDGFPITSIREIKLLQQLNHP 186
SF+ + ++G GTY VYKA++ TG ++ALK++R + ER+ + REI +L++L+HP
Sbjct: 137 SFEKIDKIGSGTYSNVYKAKDSLTGNIVALKKVRCDVNERESLKFMA-REILILRRLDHP 195
Query: 187 NISLIHEIIVSD-KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
N+ + ++ S +++ + F+YM++DL+G+ I+F++ +K MKQL GL++ H
Sbjct: 196 NVIKLEGLVTSRMSSSLYLVFRYMDHDLAGLAASPEIKFTEQQVKCYMKQLLSGLEHCHN 255
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
+ ++HRDIKGSNLLID+ G L+I DFGLA D S TNRV+TLWYR PELL G
Sbjct: 256 RGVLHRDIKGSNLLIDDGGVLRIGDFGLAT-FFDASKRQEMTNRVVTLWYRSPELLHGVV 314
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM----LDMP 361
+Y VD W GC+L EL AG AI PG NEV+Q RI + GSP+ E W K+
Sbjct: 315 EYSVGVDLWSAGCILAELLAGRAIMPGRNEVEQLHRIYKLCGSPSEEYWKKIRLPSTHKH 374
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+PQ + + V+ D FS +AL L LL D R T T+ L +FT EP
Sbjct: 375 AHHKPLPQYKRRIREVYKD-FS---PEALSLLDTLLALDPAERQTATDVLMSDFFTTEP 429
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 223 bits (569), Expect = 4e-58
Identities = 125/308 (40%), Positives = 180/308 (57%), Gaps = 15/308 (4%)
Query: 124 DVKSS---FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRL---EQERDGFPITSIREI 177
DVKS ++ L +GEG + VYKA + +T +++A+K+++L + +DG T++REI
Sbjct: 4 DVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREI 63
Query: 178 KLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLF 237
KLLQ+L+HPNI + + K+ IS+ F +ME DL ++ D S+ + S+IK M
Sbjct: 64 KLLQELSHPNIIGLLDAF-GHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTL 122
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRP 297
GL+YLHQ I+HRD+K +NLL+D G LK+ DFGLAK S + T++V+T WYR
Sbjct: 123 QGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFG--SPNRAYTHQVVTRWYRA 180
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
PELL GA Y VD W GC+L EL PG +++DQ RI +G+PT EQWP M
Sbjct: 181 PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM 240
Query: 358 LDMPWWFMLVPQISKTYKNV-FFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+P + K++ + FS D LDL L ++ R T T+AL+ YF
Sbjct: 241 CSLPDYVTF-----KSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
Query: 417 TNEPKPQP 424
+N P P P
Sbjct: 296 SNRPGPTP 303
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 222 bits (566), Expect = 8e-58
Identities = 120/295 (40%), Positives = 170/295 (56%), Gaps = 5/295 (1%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+F+ L ++G+GTY V++A TG+++ALK++R + REI +L++LNHPN
Sbjct: 120 AFEKLEKIGQGTYSNVFRAVETETGRIVALKKVRFDNFEPESVKFMAREILILRRLNHPN 179
Query: 188 ISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
I + +I S + I + F+YME+DL+G+L I+F+ IK MKQL GL + H +
Sbjct: 180 IIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIKFTTPQIKCYMKQLLSGLDHCHSR 239
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLGAT 305
++HRDIKGSNLL+ N G LK+ DFGLA T+RV+TLWYRPPELLLGAT
Sbjct: 240 GVMHRDIKGSNLLLSNEGILKVADFGLANFSNSSGHKKKPLTSRVVTLWYRPPELLLGAT 299
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
DY VD W GC+ EL G I G EV+Q +I + GSP + W K +P +
Sbjct: 300 DYGASVDLWSVGCVFAELLLGKPILRGRTEVEQLHKIFKLCGSPPEDYWKKS-KLPHAML 358
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
PQ +TY + + + + ++L LL D R T + AL YFT +P
Sbjct: 359 FKPQ--QTYDSCLRETLKDLSETEINLIETLLSIDPHKRGTASSALVSQYFTTKP 411
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 219 bits (559), Expect = 5e-57
Identities = 121/306 (39%), Positives = 181/306 (58%), Gaps = 9/306 (2%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ L ++GEGTYG VY+A + T +++ALK++R+++E+DG PI+S+REI LL +L HPNI
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98
Query: 189 SLIHEIIVSDK-NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ E++V + +I + Y E DL+ +L + FS++ +K ++ Q+ GLQYLH+
Sbjct: 99 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNF 158
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
I+HRD+K SNLL+ ++G +K DFGLA+ P T +V+TLWYR PELLLG T
Sbjct: 159 IIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM--TPKVVTLWYRAPELLLGTTTQ 216
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC+L EL A + PG++E+ Q I+ ++G+P+ WP +P LV
Sbjct: 217 TTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLP----LV 272
Query: 368 PQIS--KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
Q S K N +F + + L L L YD R T + L+ YF +P P
Sbjct: 273 GQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEP 332
Query: 426 LLGPEF 431
L P F
Sbjct: 333 ELMPTF 338
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 218 bits (556), Expect = 1e-56
Identities = 116/291 (39%), Positives = 175/291 (59%), Gaps = 18/291 (6%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L ++GEGTY VYK ++ T L+ALK +RLE E +G P T+IRE+ LL+ L H NI +
Sbjct: 168 LDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTL 226
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
H+II ++K+ +++ F+Y++ DL L D + N+K + QL GL Y H+Q+++HR
Sbjct: 227 HDIIHTEKS-LTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHR 285
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEV 311
D+K NLLI+ RG LK+ DFGLA+ + + SN V+TLWYRPP++LLG+TDY ++
Sbjct: 286 DLKPQNLLINERGELKLADFGLARAKSIPTKTYSN--EVVTLWYRPPDILLGSTDYSTQI 343
Query: 312 DCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQIS 371
D WG GC+ E+ G +FPGS +Q I I+G+PT E WP +L +
Sbjct: 344 DMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILS--------NEEF 395
Query: 372 KTYK------NVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
KTY ++ D DL +KLL+++ R + +A++H +F
Sbjct: 396 KTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 218 bits (556), Expect = 1e-56
Identities = 116/291 (39%), Positives = 175/291 (59%), Gaps = 18/291 (6%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L ++GEGTY VYK ++ T L+ALK +RLE E +G P T+IRE+ LL+ L H NI +
Sbjct: 120 LDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTL 178
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
H+II ++K+ +++ F+Y++ DL L D + N+K + QL GL Y H+Q+++HR
Sbjct: 179 HDIIHTEKS-LTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHR 237
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEV 311
D+K NLLI+ RG LK+ DFGLA+ + + SN V+TLWYRPP++LLG+TDY ++
Sbjct: 238 DLKPQNLLINERGELKLADFGLARAKSIPTKTYSN--EVVTLWYRPPDILLGSTDYSTQI 295
Query: 312 DCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQIS 371
D WG GC+ E+ G +FPGS +Q I I+G+PT E WP +L +
Sbjct: 296 DMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILS--------NEEF 347
Query: 372 KTYK------NVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
KTY ++ D DL +KLL+++ R + +A++H +F
Sbjct: 348 KTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 398
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 218 bits (556), Expect = 1e-56
Identities = 129/336 (38%), Positives = 192/336 (56%), Gaps = 11/336 (3%)
Query: 89 IPRGPRAMGSSAESAGD--SHSRNIFGKKPLALISFQDVKSS-FQPLAQVGEGTYGKVYK 145
IP P + AE A + ++ G+ AL+++ ++S F+ L ++G+GTY VYK
Sbjct: 97 IPPSPETVSKEAELAAGWPAWLVSVAGE---ALVNWTPRRASTFEKLEKIGQGTYSSVYK 153
Query: 146 AENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSD-KNTISM 204
A ++ K++ALKR+R + REI ++++L+HPN+ + +I + +++ +
Sbjct: 154 ARDLTNNKIVALKRVRFDLSDLESVKFMAREIIVMRRLDHPNVLKLEGLITASVSSSLYL 213
Query: 205 GFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRG 264
F+YM++DL G+ I+FS+ +K M+QL GL + H + ++HRDIKGSNLLID+ G
Sbjct: 214 VFEYMDHDLVGLASIPGIKFSEPQVKCYMQQLLSGLHHCHSRGVLHRDIKGSNLLIDSNG 273
Query: 265 NLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELF 324
LKI DFGLA D + T+RV+TLWYRPPELLLGA Y VD W GC+L EL+
Sbjct: 274 VLKIADFGLAT-FFDPQNCVPLTSRVVTLWYRPPELLLGACHYGVGVDLWSTGCILGELY 332
Query: 325 AGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSK 384
+G I G EV+Q +I + GSPT + W K L +P P + Y + F
Sbjct: 333 SGKPILAGKTEVEQLHKIFKLCGSPTEDYWRK-LKLPPSAAFRPAL--PYGRRVAEMFKD 389
Query: 385 VPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+P + L L LL D D R + AL+ YF EP
Sbjct: 390 LPTNVLSLLEALLSIDPDRRGSAARALESEYFRTEP 425
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 218 bits (555), Expect = 1e-56
Identities = 125/298 (41%), Positives = 183/298 (60%), Gaps = 13/298 (4%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S++ L ++GEG+Y VYK ++ GKL+ALK +RL QE +G P T+IRE LL+ L H N
Sbjct: 116 SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRL-QEEEGTPFTAIREASLLKGLKHAN 174
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
I L+H+II + K T+++ F+Y+ DL + N+K + QL GL Y+HQ+
Sbjct: 175 IVLLHDIIHT-KETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRY 233
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
I+HRD+K NLLI + G LK+ DFGLA+ + S SN V+TLWYRPP++LLG+T+Y
Sbjct: 234 ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSN--EVVTLWYRPPDVLLGSTEY 291
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEV-DQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
+D WG GC+ VE+ G A FPG ++ DQ +RI ++G+P + WP + +P +
Sbjct: 292 STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHF--- 348
Query: 367 VPQISKTY--KNV--FFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P+ Y KN+ +++ S V A DLASKLL+ R + AL H YF++ P
Sbjct: 349 KPERFTLYSSKNLRQAWNKLSYV-NHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 405
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 218 bits (555), Expect = 1e-56
Identities = 126/359 (35%), Positives = 202/359 (56%), Gaps = 19/359 (5%)
Query: 97 GSSAESAGDSHSRNIFGKKPLALIS-----FQDVKSSFQPLAQVGEGTYGKVYKA-ENVH 150
GS+ + G S SR + + I + D + ++ +A++G+GT+G+V+KA E
Sbjct: 13 GSTPSNVGSSSSRTMSLMEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREKKG 72
Query: 151 TGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSD-------KNTIS 203
K +A+K++ ++ E++GFPIT++REI++LQ L H N+ + EI + ++T
Sbjct: 73 NKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLIEICRTKATATNGYRSTFY 132
Query: 204 MGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNR 263
+ F + E+DL+G+L + +++FS IK +M+QL GL Y+H +I+HRD+K +N+LI
Sbjct: 133 LVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKH 192
Query: 264 GNLKITDFGLAKKLTDVSSPASN--TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLV 321
G LK+ DFGLA+ + + + N TNRV+TLWYRPPELLLG +Y VD WG GC++
Sbjct: 193 GILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMA 252
Query: 322 ELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML-VPQISKTYKNVFFD 380
E++ + I G+ E Q I + GS T + WP + ++ + + +P+ K
Sbjct: 253 EMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKNQKRRVKERLR 312
Query: 381 EFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL--LLGPEFKGSHEY 437
+ K Q DL KLL D R AL H +F +P P L +L + EY
Sbjct: 313 PYVK-DQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLSQHLQSMFEY 370
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 218 bits (554), Expect = 2e-56
Identities = 118/300 (39%), Positives = 179/300 (59%), Gaps = 9/300 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ L ++GEGTYG VY+A + T +++ALK++R+++E+DG PI+S+REI LL +L HPNI
Sbjct: 10 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 69
Query: 189 SLIHEIIVSDK-NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ E++V + +I + Y E DL+ +L + FS++ +K ++ Q+ GLQYLH+
Sbjct: 70 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNF 129
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
I+HRD+K SNLL+ ++G +K DFGLA+ P T +V+TLWYR PELLLG T
Sbjct: 130 IIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM--TPKVVTLWYRAPELLLGTTTQ 187
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC+L EL A + PG++E+ Q I+ ++G+P+ WP +P LV
Sbjct: 188 TTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLP----LV 243
Query: 368 PQIS--KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
Q S K N +F + + L L L YD R T + L+ YF +P P+
Sbjct: 244 GQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLRLPI 303
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 17 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 75
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 76 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 135
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 136 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 195
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 196 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 252
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 253 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 312
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 313 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 371
Query: 421 KP 422
P
Sbjct: 372 LP 373
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 349 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 407
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 408 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 467
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 468 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 527
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 528 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 584
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 585 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 644
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 645 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 703
Query: 421 KP 422
P
Sbjct: 704 LP 705
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 358 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 416
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 593
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 653
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 654 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 712
Query: 421 KP 422
P
Sbjct: 713 LP 714
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 39 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 97
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 98 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 157
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 158 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 217
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 218 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 274
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 275 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 334
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 335 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 393
Query: 421 KP 422
P
Sbjct: 394 LP 395
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 143 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 201
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 202 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 261
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 262 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 321
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 322 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 378
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 379 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 438
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 439 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 497
Query: 421 KP 422
P
Sbjct: 498 LP 499
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 326 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 384
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 385 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 444
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 445 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 504
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 505 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 561
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 562 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 621
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 622 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 680
Query: 421 KP 422
P
Sbjct: 681 LP 682
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 315 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 373
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 374 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 433
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 434 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 493
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 494 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 550
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 551 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 610
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 611 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 669
Query: 421 KP 422
P
Sbjct: 670 LP 671
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 104 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 162
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 163 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 222
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 223 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 282
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 283 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 339
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 340 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 399
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 400 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 458
Query: 421 KP 422
P
Sbjct: 459 LP 460
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 360 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 418
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 419 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 478
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 479 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 538
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 539 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 595
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 596 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 655
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 656 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 714
Query: 421 KP 422
P
Sbjct: 715 LP 716
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 218 bits (554), Expect = 2e-56
Identities = 128/362 (35%), Positives = 196/362 (53%), Gaps = 9/362 (2%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 373 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 431
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 432 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 491
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 492 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 551
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+TLWYR PEL
Sbjct: 552 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTLWYRAPEL 608
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG +E+DQ ++ +G+P+ + WP ++
Sbjct: 609 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 668
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P + Y N+ + + DL +K L Y R + + L+H YF P
Sbjct: 669 P-AVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETP 727
Query: 421 KP 422
P
Sbjct: 728 LP 729
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 218 bits (554), Expect = 2e-56
Identities = 121/311 (38%), Positives = 178/311 (56%), Gaps = 11/311 (3%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SF+ L +G+GTY VY+A ++ T +++ALK++R REI +L++LNHPN
Sbjct: 145 SFEKLEMIGQGTYSSVYRARDLETNQIVALKKVRFANMDPESVRFMAREIIILRRLNHPN 204
Query: 188 ISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ + +I+S + ++ + F+YM++DL+G+ I+FS + +QL +GL++ H
Sbjct: 205 VMKLEGLIISKASGSMYLIFEYMDHDLAGLASTPGIKFSQA------QQLLLGLEHCHSC 258
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRDIK SNLL+D NLKI DFGL+ T+RV+TLWYRPPELLLG+TD
Sbjct: 259 GVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPL-TSRVVTLWYRPPELLLGSTD 317
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC+L ELF G + PG EV+Q +I + GSP+ E W + + +
Sbjct: 318 YGVTVDLWSTGCILAELFTGKPLLPGRTEVEQMHKIFKLCGSPSEEYW-RRSRLRHATIF 376
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPLL 426
PQ YK D F +P AL L LL + D R T + ALQ +FT +P P
Sbjct: 377 KPQ--HPYKRCVADTFKDLPSSALALLEVLLAVEPDARGTASSALQSEFFTTKPFPSEPS 434
Query: 427 LGPEFKGSHEY 437
P ++ E+
Sbjct: 435 SLPRYQPRKEF 445
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 216 bits (551), Expect = 4e-56
Identities = 128/365 (35%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 353 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 411
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E +GFPITS+REI + +
Sbjct: 412 CRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILK 471
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 472 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 531
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PEL
Sbjct: 532 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPEL 588
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++
Sbjct: 589 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 648
Query: 361 PWWFMLVPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
P +V +++ Y N+ + + + DL +K L Y R + + L+H YF
Sbjct: 649 P----VVKKMTFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 704
Query: 418 NEPKP 422
P P
Sbjct: 705 ETPLP 709
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 216 bits (551), Expect = 4e-56
Identities = 128/365 (35%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 355 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQG 413
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E +GFPITS+REI + +
Sbjct: 414 CRSVDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILK 473
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 474 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PEL
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPEL 590
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++
Sbjct: 591 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 650
Query: 361 PWWFMLVPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
P +V +++ Y N+ + + + DL +K L Y R + + L+H YF
Sbjct: 651 P----VVKKMTFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 706
Query: 418 NEPKP 422
P P
Sbjct: 707 ETPLP 711
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 216 bits (550), Expect = 6e-56
Identities = 122/299 (40%), Positives = 181/299 (59%), Gaps = 13/299 (4%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
SS+ L ++GEG+Y VYK + G+L+ALK + + E +G P T+IRE LL+ L H
Sbjct: 50 SSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHA 108
Query: 187 NISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
NI L+H+II + K T++ F+YM DL+ + N++ M QL GL Y+H Q
Sbjct: 109 NIVLLHDIIHT-KETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQ 167
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRD+K NLLI + G LK+ DFGLA+ + S S+ V+TLWYRPP+ LLGAT+
Sbjct: 168 HVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSS--EVVTLWYRPPDALLGATE 225
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPG-SNEVDQFQRILSIMGSPTLEQWPKMLDM----P 361
Y E+D WG GC+ +E+F G +FPG SN ++Q ++I ++G PT + WP + + P
Sbjct: 226 YSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNP 285
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
WF P + +V ++ +VP +A DLAS++L+ R + EAL H YF+ P
Sbjct: 286 EWF---PLPTPRSLHVVWNRLGRVP-EAEDLASQMLKGFPRDRVSAQEALVHDYFSALP 340
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 216 bits (550), Expect = 6e-56
Identities = 111/299 (37%), Positives = 177/299 (59%), Gaps = 18/299 (6%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
+G+GTYG V+KA + G+ +A+K++RL +E++G +T++REIKLL++L HP+I + +
Sbjct: 17 LGQGTYGVVFKATDTKNGETVAIKKIRLGKEKEGVNVTALREIKLLKELKHPHIIELIDA 76
Query: 195 IVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIK 254
+N + + F++ME DL ++ D+++ S ++K ++ + GL+Y H + ++HRD+K
Sbjct: 77 FPHKEN-LHIVFEFMETDLEAVIRDRNLYLSPGDVKSYLQMILKGLEYCHGKWVLHRDMK 135
Query: 255 GSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLGATDYKYEVDC 313
+NLLI G LK+ DFGLA+ SP T++V WYR PELL GA Y VD
Sbjct: 136 PNNLLIGPNGQLKLADFGLARIF---GSPGRKFTHQVFARWYRAPELLFGAKQYDGAVDV 192
Query: 314 WGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP----WWFMLVPQ 369
W GC+ EL G++++DQ +I + G+P +QWP M+ +P + F+ P
Sbjct: 193 WAAGCIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDMICLPDYVEYQFVPAPS 252
Query: 370 ISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP-QPLLL 427
+ V +DALDL SK+ YD +R + +AL+H YFT+ P P PL L
Sbjct: 253 LRSL--------LPTVSEDALDLLSKMFTYDPKSRISIQQALKHRYFTSAPSPTDPLKL 303
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 216 bits (550), Expect = 6e-56
Identities = 115/289 (39%), Positives = 165/289 (56%), Gaps = 9/289 (3%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
+GEGTYG VYKA + TGK +A+K++RL +++G T++REIKLL++LNHP+I + +
Sbjct: 19 LGEGTYGVVYKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVELIDA 78
Query: 195 IVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIK 254
D ++ + F+YM+ DL ++ D++I S +IK M GL Y H++ ++HRD+K
Sbjct: 79 FPHD-GSLHLVFEYMQTDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKKWVLHRDMK 137
Query: 255 GSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLGATDYKYEVDC 313
+NLLI G LK+ DFGLA+ SP T++V WYR PELL G+ Y VD
Sbjct: 138 PNNLLIGENGLLKLADFGLARLF---GSPNRRFTHQVFATWYRAPELLFGSRQYGAGVDV 194
Query: 314 WGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKT 373
W GC+ EL PGS E+DQ +I G+P QW M+ +P + + S T
Sbjct: 195 WAAGCIFAELLLRRPFLPGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYM----EFSYT 250
Query: 374 YKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
F DALDL +K+ YD R T +AL H YF++ P P
Sbjct: 251 PAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQALDHRYFSSSPSP 299
>At1g03740 [D] KOG0600 Cdc2-related protein kinase
Length = 542
Score = 216 bits (550), Expect = 6e-56
Identities = 132/392 (33%), Positives = 201/392 (50%), Gaps = 33/392 (8%)
Query: 56 VNRSLGKRNPRGKFNRPSNGPETSGSRFEGHGSIPRGPRA---------------MGSSA 100
V L + N + R + S S F H I +G GSS
Sbjct: 116 VKAKLDRWNSKDSKVRLIESEKLSSSMFSEHHQIEKGVEKPEVEASVRVVHRELKRGSSI 175
Query: 101 ESAGDSHSRNIFGKKPLALISFQDVK---------SSFQPLAQVGEGTYGKVYKAENVHT 151
S D+ + + P L+S ++F+ L ++G+GTY VY+A ++
Sbjct: 176 VSPKDAERKQVAAGWPSWLVSVAGESLVDWAPRRANTFEKLEKIGQGTYSSVYRARDLLH 235
Query: 152 GKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSD-KNTISMGFQYME 210
K++ALK++R + REI ++++L+HPN+ + +I + +++ + F+YM+
Sbjct: 236 NKIVALKKVRFDLNDMESVKFMAREIIVMRRLDHPNVLKLEGLITAPVSSSLYLVFEYMD 295
Query: 211 NDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITD 270
+DL G+ ++F++ +K M+QL GL++ H + ++HRDIKGSNLLID++G LKI D
Sbjct: 296 HDLLGLSSLPGVKFTEPQVKCYMRQLLSGLEHCHSRGVLHRDIKGSNLLIDSKGVLKIAD 355
Query: 271 FGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIF 330
FGLA D + S T+ V+TLWYRPPELLLGA+ Y VD W GC+L EL+AG I
Sbjct: 356 FGLAT-FFDPAKSVSLTSHVVTLWYRPPELLLGASHYGVGVDLWSTGCILGELYAGKPIL 414
Query: 331 PGSNEVDQFQRILSIMGSPTLEQW--PKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQD 388
PG EV+Q +I + GSPT W K+ + +P Y+ + F P
Sbjct: 415 PGKTEVEQLHKIFKLCGSPTENYWRKQKLPSSAGFKTAIP-----YRRKVSEMFKDFPAS 469
Query: 389 ALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
L L LL D D R + AL+ YF +P
Sbjct: 470 VLSLLETLLSIDPDHRSSADRALESEYFKTKP 501
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 216 bits (549), Expect = 7e-56
Identities = 128/365 (35%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 355 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQG 413
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 414 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 473
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 474 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 533
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PEL
Sbjct: 534 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPEL 590
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++
Sbjct: 591 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 650
Query: 361 PWWFMLVPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
P +V +++ Y N+ + + DL +K L Y R + + L+H YF
Sbjct: 651 P----VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 706
Query: 418 NEPKP 422
P P
Sbjct: 707 ETPLP 711
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 216 bits (549), Expect = 7e-56
Identities = 128/365 (35%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 358 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQG 416
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 476
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 477 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 536
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PEL
Sbjct: 537 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPEL 593
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++
Sbjct: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653
Query: 361 PWWFMLVPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
P +V +++ Y N+ + + DL +K L Y R + + L+H YF
Sbjct: 654 P----VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
Query: 418 NEPKP 422
P P
Sbjct: 710 ETPLP 714
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 216 bits (549), Expect = 7e-56
Identities = 128/365 (35%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 345 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQG 403
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 404 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 463
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 464 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 523
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PEL
Sbjct: 524 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPEL 580
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++
Sbjct: 581 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 640
Query: 361 PWWFMLVPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
P +V +++ Y N+ + + DL +K L Y R + + L+H YF
Sbjct: 641 P----VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 696
Query: 418 NEPKP 422
P P
Sbjct: 697 ETPLP 701
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 216 bits (549), Expect = 7e-56
Identities = 128/365 (35%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 65 PRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQD 124
P +F+R S E + G G+ G + + + P L + Q
Sbjct: 354 PESRFDRDSGESEEAEEEV-GEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQG 412
Query: 125 VKS--SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+S FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + +
Sbjct: 413 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK 472
Query: 183 LNHPNISLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
HPNI + EI+V S+ + I + Y+E+DL ++ F +K LM QL G++
Sbjct: 473 AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVK 532
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPEL 300
+LH I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PEL
Sbjct: 533 HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPEL 589
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LLGA +Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++
Sbjct: 590 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 649
Query: 361 PWWFMLVPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
P +V +++ Y N+ + + DL +K L Y R + + L+H YF
Sbjct: 650 P----VVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 705
Query: 418 NEPKP 422
P P
Sbjct: 706 ETPLP 710
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 216 bits (549), Expect = 7e-56
Identities = 122/314 (38%), Positives = 178/314 (55%), Gaps = 8/314 (2%)
Query: 110 NIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGF 169
N+ G+ + F+ +F+ L ++G+GTY V++A TG+++ALK++R +
Sbjct: 114 NVAGEAIHGWVPFRS--DAFEKLEKIGQGTYSSVFRARETETGRIVALKKVRFDNFEPES 171
Query: 170 PITSIREIKLLQQLNHPNISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSN 228
REI +L++LNHPNI + I+ S + +I + F+YME+DL+G+L I F+
Sbjct: 172 VRFMAREILILRKLNHPNIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDIDFTTPQ 231
Query: 229 IKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTN 288
IK MKQL GL + H + ++HRDIKGSNLL++N G LK+ DFGLA + T+
Sbjct: 232 IKCYMKQLLSGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPLTS 291
Query: 289 RVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGS 348
RV+TLWYRPPELLLGAT+Y VD W GC+ EL G + G EV+Q +I + GS
Sbjct: 292 RVVTLWYRPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRTEVEQLHKIFKLCGS 351
Query: 349 PTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFS-KVPQDA-LDLASKLLRYDQDTRFT 406
P + W K +P + PQ + Y + K DA ++L LL R T
Sbjct: 352 PPEDYWKKS-KLPHAMLFKPQ--QHYDGCLRETLKLKGLSDADINLIETLLSIQPHKRGT 408
Query: 407 TTEALQHHYFTNEP 420
+ AL YFT++P
Sbjct: 409 ASTALVSQYFTSKP 422
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 215 bits (548), Expect = 1e-55
Identities = 113/315 (35%), Positives = 191/315 (59%), Gaps = 15/315 (4%)
Query: 109 RNIFGK-KPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERD 167
+N+FG+ +P+ S F+ L +VGEG+YG VY+A + + +++ALK++R++QE+D
Sbjct: 41 QNLFGRCRPV---------SEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKD 91
Query: 168 GFPITSIREIKLLQQLNHPNISLIHEIIVSDK-NTISMGFQYMENDLSGMLMDKSIQFSD 226
G PI+ +REI +L+Q +H NI + E++V ++I + + E DL+ +L + S F++
Sbjct: 92 GLPISGLREIMILKQCHHENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTE 151
Query: 227 SNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN 286
S +K + Q+ L+YLH + ++HRD+K SNLL+ ++G +K+ DFGLA+ ++ P
Sbjct: 152 SEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPM-- 209
Query: 287 TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIM 346
T +++TLWYR PELLLG + VD W GC+L EL G + PG++E+ Q I+ ++
Sbjct: 210 TPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLL 269
Query: 347 GSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFT 406
G+P+ WP D+P + +S+ N +F + Q +L + L Y+ TR T
Sbjct: 270 GAPSESIWPGFADLP--AVQNFTLSQQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRAT 327
Query: 407 TTEALQHHYFTNEPK 421
E L+ YF + P+
Sbjct: 328 AEECLKSKYFVDPPQ 342
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 215 bits (547), Expect = 1e-55
Identities = 116/299 (38%), Positives = 179/299 (59%), Gaps = 12/299 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI + + HPNI
Sbjct: 40 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI 99
Query: 189 SLIHEIIV-SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ EI+V S+ + I + Y+E+DL ++ F +K LM QL G+++LH
Sbjct: 100 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW 159
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSP-ASNTNRVITLWYRPPELLLGATD 306
I+HRD+K SNLL+ + G LK+ DFGLA+ + SP + T V+T WYR PELLLGA +
Sbjct: 160 ILHRDLKTSNLLLSHAGILKVGDFGLAR---EYGSPLKAYTPVVVTQWYRAPELLLGAKE 216
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC+ EL +FPG++E+DQ ++ +G+P+ + WP ++P +
Sbjct: 217 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELP----V 272
Query: 367 VPQIS---KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
V +++ Y N+ + + DL +K L Y R + + L+H YF P P
Sbjct: 273 VKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLP 331
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 214 bits (546), Expect = 2e-55
Identities = 118/301 (39%), Positives = 174/301 (57%), Gaps = 9/301 (2%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+FQ + ++GEGTYG VYKA N TG+++ALK++RL+ E +G P T+IREI LL++LNHPN
Sbjct: 3 NFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN 62
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKS--IQFSDSNIKHLMKQLFVGLQYLHQ 245
I + ++I ++ N + + F+++ DL MD S IK + QL GL + H
Sbjct: 63 IVKLLDVIHTE-NKLYLVFEFLHQDLK-KFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
+++HRD+K NLLI+ G +K+ DFGLA+ + T+ V+TLWYR PE+LLG
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFG--VPVRTYTHEVVTLWYRAPEILLGCK 178
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y VD W GC+ E+ A+FPG +E+DQ RI +G+P WP + MP +
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-- 236
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
P K + F + +D L S++L YD + R + AL H +F + KP P
Sbjct: 237 -KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPH 295
Query: 426 L 426
L
Sbjct: 296 L 296
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 214 bits (546), Expect = 2e-55
Identities = 119/320 (37%), Positives = 190/320 (59%), Gaps = 20/320 (6%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL-NHPN 187
++ + +V EGT+G VY+ ++ T +++ALKRL++E+E++GFPIT++REI +L + NHPN
Sbjct: 356 YECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHPN 415
Query: 188 ISLIHEIIV-SDKNTISMGFQYMENDLSGML---MDKSIQFSDSNIKHLMKQLFVGLQYL 243
I + EI++ S+ + I M +++E+D+ +L ++ +FS K L++QL G++++
Sbjct: 416 IVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHM 475
Query: 244 HQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLG 303
H+ I+HRD+K SNLL+ ++G LKI DFGLA++ D T+ V+TLWYR PELLLG
Sbjct: 476 HKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKF--TSIVVTLWYRSPELLLG 533
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y VD W GC++ E +FPG E++Q ++I MG+PT WP + ++ W
Sbjct: 534 TRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGW 593
Query: 364 FMLVPQISKTYKNVFFDEFSK-------VPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
L T++ +++ K + L + LL D RF+ T+AL H +F
Sbjct: 594 KAL------TFEKYPYNQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWF 647
Query: 417 TNEPKPQPLLLGPEFKGSHE 436
T EP P P P F E
Sbjct: 648 TEEPYPVPPEEFPTFPAKSE 667
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 214 bits (544), Expect = 3e-55
Identities = 135/401 (33%), Positives = 215/401 (52%), Gaps = 38/401 (9%)
Query: 37 SRYQPNRPNNHHNTAGNVNVNRSLGKRNPRGKFNRPSNGPETSGSRFEGHGSIPRG-PRA 95
SR +R NN T V +N+ N PS P S + + R PR+
Sbjct: 35 SRQSRSRSNNPSETMSTVPLNK-----------NSPSMPPPPSSNTVADFTHLRRRRPRS 83
Query: 96 MGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLI 155
+ D ++ + K+ ++ QDV ++ + ++GEG+Y VYK E+ G ++
Sbjct: 84 ------AHYDPNTITLPAKEE---VTPQDVNDLYKRIDKLGEGSYATVYKCESKLDGSIV 134
Query: 156 ALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSG 215
ALK ++L Q ++G P T+IRE LL+ L H NI +H+I + ++ F+YM+ DLS
Sbjct: 135 ALKEIKL-QFQEGLPFTAIREASLLRNLRHANIVSLHDIFYQH-HQLTFVFEYMKMDLSK 192
Query: 216 MLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAK 275
L +IK L+ QL GL + H+++I+HRD+K NLL+D G LK+ DFGLA+
Sbjct: 193 YLEQNVYGLDSIDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLAR 252
Query: 276 KLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNE 335
+ S S+ V+TLWYRPP++L+G+TDY +D WG GC+ E+ GAA+FPGS +
Sbjct: 253 AKSVPSRTYSH--EVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGSKD 310
Query: 336 ------VDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFF----DEFSKV 385
DQ I SI G+P ++WP++ +P + P++ Y+ + F F+K+
Sbjct: 311 SHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLPGY---TPELFPRYRELSFIAVNPMFTKI 367
Query: 386 PQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPLL 426
+ +L LL+ ++R + A+ H YF + P+ LL
Sbjct: 368 LKTGQELLGMLLQLRPESRVSAASAMLHPYFASFPREVHLL 408
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 213 bits (542), Expect = 5e-55
Identities = 116/315 (36%), Positives = 175/315 (54%), Gaps = 24/315 (7%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
+G+GTYG V+KA + T + +A+K++RL ++R+G IT++REIK+L++L HP+I L+ +
Sbjct: 18 LGQGTYGVVFKATDTKTEQTVAIKKIRLGKQREGVNITALREIKMLKELKHPHIILLIDA 77
Query: 195 IVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIK 254
+N + + F++ME DL ++ D +I S ++IK + F GL Y H + ++HRD+K
Sbjct: 78 FPHKEN-LHLVFEFMETDLEAVIRDSNIFLSPADIKSYLLMTFKGLAYCHDKWVLHRDMK 136
Query: 255 GSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCW 314
+NLLI G LK+ DFGLA+ S T++V WYR PELL GA Y VD W
Sbjct: 137 PNNLLIGVDGQLKLADFGLARIFG--SPNRKFTHQVFARWYRAPELLFGAKQYGAAVDVW 194
Query: 315 GCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP----WWFMLVPQI 370
C+ EL G++++DQ +I + G+P +QWP + +P + F+ P +
Sbjct: 195 AVACIFAELLLRRPFLQGNSDIDQLSKIFAAFGTPKADQWPDLTKLPDYVEYQFVPAPSL 254
Query: 371 SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNE---------PK 421
F V DALDL SK+ YD R + +AL+H YFT+ PK
Sbjct: 255 RSL--------FPAVSDDALDLLSKMFTYDPKARISIKQALEHRYFTSAPAPTDPAKLPK 306
Query: 422 PQPLLLGPEFKGSHE 436
P P G G HE
Sbjct: 307 PVPKQDGKSSYGKHE 321
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 212 bits (540), Expect = 8e-55
Identities = 109/304 (35%), Positives = 175/304 (56%), Gaps = 4/304 (1%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L ++ EG+YG VY+ + T L+ALK+++ + GFPITS+REI+ L + H NI
Sbjct: 74 YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNI 133
Query: 189 SLIHEIIVS-DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ +++V D + + ++ME+DL +L + F S +K LM QL ++H
Sbjct: 134 VELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHW 193
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
+HRD+K SNLL++N G +K+ DFGLA+ +++ S S T V+TLWYR PELLLGA Y
Sbjct: 194 YLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKS--SLTRLVVTLWYRAPELLLGAPSY 251
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
E+D W GC+ E+ +F G +E+DQ +I +++G PT E+WP+ +P+ +
Sbjct: 252 GKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYANKIK 311
Query: 368 PQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPLLL 427
T+ + + +A DL ++LL + R + EAL+H YF P+P+
Sbjct: 312 HPTVPTHSKI-RTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYESPRPKDPKF 370
Query: 428 GPEF 431
P F
Sbjct: 371 FPTF 374
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 212 bits (539), Expect = 1e-54
Identities = 109/294 (37%), Positives = 176/294 (59%), Gaps = 24/294 (8%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L ++GEGTY VYK + T L+ALK +RLE E +G P T+IRE+ LL+ L H NI +
Sbjct: 195 LEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTL 253
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
H+I+ +DK+ +++ F+Y++ DL + D S N+K + Q+ GL Y H+++++HR
Sbjct: 254 HDIVHTDKS-LTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHR 312
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEV 311
D+K NLLI+ +G LK+ DFGLA+ + + SN V+TLWYRPP++LLG+++Y ++
Sbjct: 313 DLKPQNLLINEKGELKLADFGLARAKSVPTKTYSN--EVVTLWYRPPDVLLGSSEYLTQI 370
Query: 312 DCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQIS 371
D WG GC+ E+ +G +FPGS D+ I ++G+P+ E WP + +
Sbjct: 371 DMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGI-----------SSN 419
Query: 372 KTYKNVFFDEFSKVP---------QDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ +KN F ++ P + ++L K L+Y+ R + EA++H YF
Sbjct: 420 EEFKNYNFPKYKPEPLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAMKHVYF 473
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 212 bits (539), Expect = 1e-54
Identities = 107/289 (37%), Positives = 177/289 (61%), Gaps = 8/289 (2%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+++ L ++GEGTY V++ ++ T K +ALK +RLEQE +G P T+IRE+ LL+ L H N
Sbjct: 360 TYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQE-EGAPCTAIREVSLLRNLRHAN 418
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ +H+II +D+ +++ F+Y++ DL + + +NI+ + QL GL Y HQ++
Sbjct: 419 VVTLHDIIHTDR-LLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRR 477
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
++HRD+K NLLI +G LK+ DFGLA+ + + SN V+TLWYRPP++LLG+TDY
Sbjct: 478 VLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSN--EVVTLWYRPPDVLLGSTDY 535
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D WG GC+L E+ AG A+FPG +Q I +GSP ++ P + + P ++
Sbjct: 536 STHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFY--- 592
Query: 368 PQISKTYK-NVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
P ++ Y + + ++ +L K L+Y+ R + EA++H +
Sbjct: 593 PYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPF 641
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 212 bits (539), Expect = 1e-54
Identities = 107/289 (37%), Positives = 177/289 (61%), Gaps = 8/289 (2%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+++ L ++GEGTY V++ ++ T K +ALK +RLEQE +G P T+IRE+ LL+ L H N
Sbjct: 237 TYEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQE-EGAPCTAIREVSLLRNLRHAN 295
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ +H+II +D+ +++ F+Y++ DL + + +NI+ + QL GL Y HQ++
Sbjct: 296 VVTLHDIIHTDR-LLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQRR 354
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
++HRD+K NLLI +G LK+ DFGLA+ + + SN V+TLWYRPP++LLG+TDY
Sbjct: 355 VLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSN--EVVTLWYRPPDVLLGSTDY 412
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D WG GC+L E+ AG A+FPG +Q I +GSP ++ P + + P ++
Sbjct: 413 STHIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFY--- 469
Query: 368 PQISKTYK-NVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
P ++ Y + + ++ +L K L+Y+ R + EA++H +
Sbjct: 470 PYANRHYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPF 518
>CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 489
Score = 211 bits (537), Expect = 2e-54
Identities = 145/447 (32%), Positives = 219/447 (48%), Gaps = 77/447 (17%)
Query: 31 YHGG---SQSRYQPNRPNNHHNTAGNVNVNRSLGKRNPRGKFNRPSNGPETSGSRFEGHG 87
YH G S ++ P RPN H + P+ P +SG G
Sbjct: 6 YHAGLHQSSTQRPPKRPNTEH------------AQEPPKRALIGGQTTPSSSGG-----G 48
Query: 88 SIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKV---- 143
P G + S+ + +F + I +DV S+++ L ++G+GT+G+V
Sbjct: 49 QTPNGTNYELEVKQQL--SNYQKLFDQATYPFI--RDV-STYEKLNKIGQGTFGQVLQGR 103
Query: 144 -------YKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIV 196
+KA +TG+++ALK++ +E E++GFPIT++RE+K+L+QL HPNI+ + E+
Sbjct: 104 KSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCS 163
Query: 197 S---------DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ D+ T + +DL+G+L + I+ S +IK +MK L GL LH+ +
Sbjct: 164 AKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSK 223
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN----TNRVITLWYRPPELLLG 303
I+HRD+K +N+LI G LK+ DFGLA+ + A TNRV+TLWYRPPELLLG
Sbjct: 224 ILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLG 283
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y ++D WG GC++ E++ I G E Q Q I + GS + WP ++MP W
Sbjct: 284 DRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLW 343
Query: 364 FML-------VPQ-----ISKTYKNVF--------FDEFSK--------VPQDALDLASK 395
+ +PQ + KN+ D F K DAL L
Sbjct: 344 SAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEI 403
Query: 396 LLRYDQDTRFTTTEALQHHYFTNEPKP 422
LL D D R T+ EA +F +P P
Sbjct: 404 LLAIDPDKRPTSDEAEDDIWFFKDPVP 430
>CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 456
Score = 211 bits (537), Expect = 2e-54
Identities = 145/447 (32%), Positives = 219/447 (48%), Gaps = 77/447 (17%)
Query: 31 YHGG---SQSRYQPNRPNNHHNTAGNVNVNRSLGKRNPRGKFNRPSNGPETSGSRFEGHG 87
YH G S ++ P RPN H + P+ P +SG G
Sbjct: 6 YHAGLHQSSTQRPPKRPNTEH------------AQEPPKRALIGGQTTPSSSGG-----G 48
Query: 88 SIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKV---- 143
P G + S+ + +F + I +DV S+++ L ++G+GT+G+V
Sbjct: 49 QTPNGTNYELEVKQQL--SNYQKLFDQATYPFI--RDV-STYEKLNKIGQGTFGQVLQGR 103
Query: 144 -------YKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIV 196
+KA +TG+++ALK++ +E E++GFPIT++RE+K+L+QL HPNI+ + E+
Sbjct: 104 KSRNSEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCS 163
Query: 197 S---------DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ D+ T + +DL+G+L + I+ S +IK +MK L GL LH+ +
Sbjct: 164 AKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSK 223
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN----TNRVITLWYRPPELLLG 303
I+HRD+K +N+LI G LK+ DFGLA+ + A TNRV+TLWYRPPELLLG
Sbjct: 224 ILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLG 283
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y ++D WG GC++ E++ I G E Q Q I + GS + WP ++MP W
Sbjct: 284 DRQYGTKIDVWGAGCIMAEMWTRQPIMQGDTEQKQLQLISGLCGSINKDVWPNCVNMPLW 343
Query: 364 FML-------VPQ-----ISKTYKNVF--------FDEFSK--------VPQDALDLASK 395
+ +PQ + KN+ D F K DAL L
Sbjct: 344 SAMSSEPNSALPQGKYRILPNKMKNLMKFDAPDSKTDPFGKNVKQHDSATDDDALHLLEI 403
Query: 396 LLRYDQDTRFTTTEALQHHYFTNEPKP 422
LL D D R T+ EA +F +P P
Sbjct: 404 LLAIDPDKRPTSDEAEDDIWFFKDPVP 430
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 210 bits (535), Expect = 3e-54
Identities = 111/294 (37%), Positives = 167/294 (56%), Gaps = 8/294 (2%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
+ +FQ ++GEGTYG VYKA + TG+ +ALK++RLE E +G P T+IREI LL+ L
Sbjct: 4 ILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLK 63
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
HPN+ + ++++S N + M F+Y+ DL ++ K F+ IK M Q+ + + H
Sbjct: 64 HPNVVQLFDVVISG-NNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCH 122
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGA 304
+I+HRD+K NLL+D G +K+ DFGLA+ + T+ V+TLWYR PE+LLG
Sbjct: 123 TNRILHRDLKPQNLLVDTAGKIKLADFGLARAFN--VPMRAYTHEVVTLWYRAPEILLGT 180
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
Y VD W GC+ E+ ++FPG +E+DQ RI + +P WP + +P +
Sbjct: 181 KFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFK 240
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
P+ T E +A +L +L YD + R + +ALQH YF N
Sbjct: 241 TKFPRWEGTNMPQPITE-----HEAHELIMSMLCYDPNLRISAKDALQHAYFRN 289
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 210 bits (534), Expect = 4e-54
Identities = 113/298 (37%), Positives = 178/298 (58%), Gaps = 10/298 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
FQ + ++GEGTYG VYKA+N TG+L+ALK++RL+ E +G P T+IREI LL++L HPNI
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKS--IQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ +++ +++ + + F+++ DL MD + + IK + QL G+ + H
Sbjct: 64 VRLLDVVHNERK-LYLVFEFLSQDLK-KYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
+++HRD+K NLLI+ G +K+ DFGLA+ + T+ V+TLWYR PE+LLG+
Sbjct: 122 RVIHRDLKPQNLLINELGAIKLADFGLARAFG--VPLRTYTHEVVTLWYRAPEILLGSKF 179
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC+ E+ A+FPG +E+DQ RI ++G+P+ + WP + +P +
Sbjct: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQP 424
P K + + + + DL +LL+YD R T AL H YF++ P+P P
Sbjct: 240 FP---KWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSP 293
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 209 bits (532), Expect = 7e-54
Identities = 114/307 (37%), Positives = 177/307 (57%), Gaps = 9/307 (2%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN-H 185
S + L + EGTYG+V++ +N T +++ALKR ++E+E++GFPIT++REI +L + H
Sbjct: 397 SEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALREINMLLKAGAH 456
Query: 186 PNISLIHEIIV-SDKNTISMGFQYMENDLSGML---MDKSIQFSDSNIKHLMKQLFVGLQ 241
NI + EI+V S K + M +Y+E+D+ ++ ++ +F K LM QL G++
Sbjct: 457 ENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQLLSGIE 516
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKL---TDVSSPASNTNRVITLWYRPP 298
++H+ I+HRD+K SNLLI + G LKI DFGLA++ D+ T V+TLWYR P
Sbjct: 517 HMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSP 576
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
ELLL Y VD W GC++ E +F G +E +Q +I +MG+PT + WP +
Sbjct: 577 ELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWPDIK 636
Query: 359 DMPWWFML-VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
++ W M+ P + F V + DL + +L + R T +EALQH +F+
Sbjct: 637 ELKVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFS 696
Query: 418 NEPKPQP 424
PK P
Sbjct: 697 EHPKAVP 703
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 208 bits (530), Expect = 1e-53
Identities = 121/313 (38%), Positives = 172/313 (54%), Gaps = 6/313 (1%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNH 185
+S F+ Q+G GT+ KV+KA ++ K +ALKR+R + REI +L++L+H
Sbjct: 100 ESHFEKQEQIGGGTFSKVFKARDLLRNKTVALKRIRFDINNSESIKCIAREIIILRKLDH 159
Query: 186 PNISLIHEIIV--SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
PN+ + +++ D +T+ + F+YME+DL G+ + FS+ +K M+QL GL +
Sbjct: 160 PNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHFSEPQVKCYMRQLLRGLDHC 219
Query: 244 HQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLG 303
H ++HRD+K SNLLI+ G LKI DFGLA D + T V TLWYRPPELLLG
Sbjct: 220 HTNHVLHRDMKSSNLLINGDGVLKIADFGLAT-FFDPHNSVPLTTHVATLWYRPPELLLG 278
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
A+ Y VD W GC++ EL+AG I PG NE DQ +I + GSP+ + W K L +
Sbjct: 279 ASHYGIGVDLWSTGCVIGELYAGKPILPGKNETDQLHKIFKLCGSPSDDYWTK-LKLQLS 337
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQ 423
L P Y + + F + P + L LL D D R T AL+ YF EP
Sbjct: 338 TPLRP--IYPYGSHIAETFKQFPASVISLLETLLSIDPDFRGTAASALKSKYFKTEPLAC 395
Query: 424 PLLLGPEFKGSHE 436
P++ S E
Sbjct: 396 DPSCLPKYPSSKE 408
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 207 bits (528), Expect = 2e-53
Identities = 111/297 (37%), Positives = 165/297 (55%), Gaps = 12/297 (4%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
SFQ L ++GEGTYG VYKA +T +++ALK++RLE E +G P T+IREI LL+ L H
Sbjct: 4 SFQKLEKIGEGTYGVVYKARERNTNRVVALKKIRLENENEGIPATTIREILLLKNLKHST 63
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGML---MDKSIQFSDSNIKHLMKQLFVGLQYLH 244
I + ++I ++ N + + F+Y+E DL L D+ + ++ + +QL ++Y H
Sbjct: 64 IVELSDVIYNN-NKMYLVFEYVELDLRRYLDRMSDEGRLVEEGFVRKMSQQLLTAMEYCH 122
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLG 303
+ I HRD+K N+L+D + N+K+ DFGL + P T V+TLWYRPPELLLG
Sbjct: 123 SRNIFHRDLKPQNILVDPKENIKLADFGLGRA---AGIPLRTYTTEVVTLWYRPPELLLG 179
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y VD W C++ E+ FPG +E+DQ RI ++G+P +W + + P +
Sbjct: 180 CKYYDASVDVWSAACIMAEVVLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVENFPNY 239
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+ P + V + D +DL SK+L YD R T L H YF P
Sbjct: 240 KVEFP----VWDPVDLKTIFRGDPDFVDLISKMLEYDPKMRMTAKNGLSHKYFEGMP 292
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 207 bits (527), Expect = 3e-53
Identities = 108/292 (36%), Positives = 175/292 (58%), Gaps = 11/292 (3%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
++Q L ++GEGTY VYK +N TG+++ALK +R++ + +G P T+IREI L+++L HPN
Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDAD-EGTPSTAIREISLMKELRHPN 60
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ--FSDSNIKHLMKQLFVGLQYLHQ 245
I + +++ ++ N + + F+YME DL + Q S +K+ +QL G+ + H+
Sbjct: 61 IMSLSDVLQTE-NKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHE 119
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLGA 304
+++HRD+K NLLI++RG LK+ DFGLA+ + P + +N V+TLWYR P++LLG+
Sbjct: 120 NRVLHRDLKPQNLLINSRGELKLADFGLARS---IGIPVNTFSNEVVTLWYRAPDVLLGS 176
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
Y +D W GC++ E+ G +F GSN DQ +I ++G+PT + WP + +P +
Sbjct: 177 RVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYK 236
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
P F F + LDL ++LR + R T +ALQH +F
Sbjct: 237 PTFPIYKAQDLAYLFPTFDPL---GLDLLRRMLRLQPELRTTGQDALQHAWF 285
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 207 bits (526), Expect = 3e-53
Identities = 131/379 (34%), Positives = 197/379 (51%), Gaps = 19/379 (5%)
Query: 34 GSQSRYQPNRPNNHHNTAGNVNVNRSLGKRNPRGKFNRPSNGPETSGSRFEGHGSIPRGP 93
G S Q +R H+ + N RS R G R +S E + P
Sbjct: 24 GLLSTSQQHRVLIDHSLEASHNSKRSRKSRRLGGSDLRIGVSLGSSHRNIEAEQAAAGWP 83
Query: 94 RAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGK 153
+ S+A A + G PL +FQ L ++G+GTY V++A V TGK
Sbjct: 84 AWLCSAAAEA-------VHGWVPLKA-------EAFQKLEKIGQGTYSSVFRAREVETGK 129
Query: 154 LIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSD-KNTISMGFQYMEND 212
++ALK+++ + + REI +L++LNHPNI + I+ S ++I + F+YME+D
Sbjct: 130 MVALKKVKFDNLQPESIRFMAREILILRKLNHPNIMKLEGIVTSRASSSIYLVFEYMEHD 189
Query: 213 LSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFG 272
L+G+ + I+F++ IK MKQL GL++ H + ++HRDIK SN+L++N+G LK+ DFG
Sbjct: 190 LAGLSSNPDIRFTEPQIKCYMKQLLWGLEHCHMRGVIHRDIKASNILVNNKGVLKLGDFG 249
Query: 273 LAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPG 332
LA +T S+ T+RV+TLWYR PELL+G+T Y VD W GC+ E+ G I G
Sbjct: 250 LANVVTP-SNKNQLTSRVVTLWYRAPELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKG 308
Query: 333 SNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDL 392
E++Q +I + GSP W K +P PQ TY+ + + + L
Sbjct: 309 RTEIEQLHKIYKLCGSPQDSFW-KRTKLPHATSFKPQ--HTYEATLRERCKDLSATGVYL 365
Query: 393 ASKLLRYDQDTRFTTTEAL 411
LL + D R T + AL
Sbjct: 366 LETLLSMEPDKRGTASSAL 384
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 206 bits (524), Expect = 6e-53
Identities = 112/295 (37%), Positives = 171/295 (57%), Gaps = 18/295 (6%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
++ L ++GEGTY V+K + T L+ALK +RLE E +G P T+IRE+ LL+ L H N
Sbjct: 141 TYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHAN 199
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
I +H++I +D++ +++ F+Y+++DL L S N+K M QL GL Y H ++
Sbjct: 200 IVTLHDLIHTDRS-LTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRK 258
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
I+HRD+K NLLI+ RG LK+ DFGLA+ + + SN V+TLWYRPP++LLG+T+Y
Sbjct: 259 ILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSN--EVVTLWYRPPDVLLGSTEY 316
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D WG GC+ E+ G +FPGS ++ I ++G+PT E WP + +
Sbjct: 317 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEF---- 372
Query: 368 PQISKTYK------NVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+TY + ++ D + L S LL Y+ +R + AL H YF
Sbjct: 373 ----RTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 423
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 205 bits (521), Expect = 1e-52
Identities = 109/293 (37%), Positives = 172/293 (58%), Gaps = 11/293 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L ++GEGTYG V+KA+N T +++ALKR+RL+ + +G P +++REI LL++L H NI
Sbjct: 4 YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+H+++ SDK +++ F++ + DL + +K + QL GL + H + +
Sbjct: 64 VRLHDVLHSDKK-LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNV 122
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRD+K NLLI+ G LK+ DFGLA+ + V+TLWYRPP++L GA Y
Sbjct: 123 LHRDLKPQNLLINRNGELKLADFGLARAFG--IPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 309 YEVDCWGCGCLLVELF-AGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW--FM 365
+D W GC+ EL AG +FPG++ DQ +RI ++G+PT EQWP M +P + +
Sbjct: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP 240
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+ P + V K+ DL LL+ + R + EALQH YF++
Sbjct: 241 MYPATTSLVNVV-----PKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 205 bits (521), Expect = 1e-52
Identities = 116/305 (38%), Positives = 176/305 (57%), Gaps = 16/305 (5%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
FQ L ++ EGTYG VY+A++ T +++ALKRL++E+E++GFPITS+REI L + HPNI
Sbjct: 558 FQCLNRIEEGTYGVVYRAKDKRTNEIVALKRLKMEKEKEGFPITSLREINTLLKGQHPNI 617
Query: 189 SLIHEIIV-SDKNTISMGFQYMENDLSGM---LMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
+ EI+V S+ + I + Y+E+DL + + ++ F +K L +QL + +LH
Sbjct: 618 VTVREIVVGSNMDKIFIVMDYVEHDLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLH 677
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLG 303
I+HRD+K SNLL+ ++G LK+ DFGLA+ + SP T+ V+TLWYR PELLL
Sbjct: 678 DNWILHRDLKTSNLLLSHKGILKVGDFGLAR---EYGSPIKKYTSLVVTLWYRAPELLLC 734
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
+ Y +D W GC+ E +FPG +E+D+ RI +G+P + WP ++P
Sbjct: 735 SPVYSTPIDVWSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTPNEKIWPGYTELPAV 794
Query: 364 FMLVPQISK------TYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
++ Q S+ + F E K + L L LL YD R + AL+H +F
Sbjct: 795 KNMLSQNSQFTEYPVSQLRKHFQE--KTSEMGLSLLQGLLTYDPKQRLSADAALKHGFFK 852
Query: 418 NEPKP 422
P P
Sbjct: 853 ELPLP 857
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 204 bits (520), Expect = 2e-52
Identities = 115/292 (39%), Positives = 169/292 (57%), Gaps = 12/292 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ + ++GEGTYG VYKA + T + IALK++RLEQE +G P T+IREI LL+++ H NI
Sbjct: 4 YEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNI 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDS--NIKHLMKQLFVGLQYLHQQ 246
+++ S+K + + F+Y++ DL MD + FS IK + Q+ G+ Y H
Sbjct: 64 VKYDDVVHSEKR-LYLVFEYLDLDLKKH-MDSTPDFSKDLHMIKTYLYQILRGIAYCHSH 121
Query: 247 QIVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLGA 304
+++HRD+K NLLID R N LK+ DFGLA+ P T+ V+TLWYR PE+LLG+
Sbjct: 122 RVLHRDLKPQNLLIDRRTNSLKLADFGLARAF---GIPVRTFTHEVVTLWYRAPEILLGS 178
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
Y VD W GC+ E+ + +FPG +E+DQ +I IMG+P + W + +P +
Sbjct: 179 HHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYK 238
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
P+ T F + D +DL SK+L D R AL+H YF
Sbjct: 239 SAFPKWKPTDLETF---VPNLDPDGVDLLSKMLLMDPTKRINARAALEHEYF 287
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 201 bits (512), Expect = 1e-51
Identities = 104/295 (35%), Positives = 169/295 (57%), Gaps = 31/295 (10%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRL---EQERDGFPITSIREIKLLQQLNH 185
+ + +GEG + VY A+++ +G+ +A+K+++L E+ +DG T+IREIKLL++++H
Sbjct: 5 YDTIKHLGEGQFANVYLAQDLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHH 64
Query: 186 PNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
NI + ++I + +I + F +M+ DL ++ DK I ++IK++ Q+ +GL++LH
Sbjct: 65 DNIIGLRDVI-GHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHV 123
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I+HRD+K +NLL++ G RV+T WYR PELL GA
Sbjct: 124 HWILHRDLKPNNLLMNKMG------------------------RVVTRWYRAPELLFGAR 159
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y +D W GC++ EL IFPG +++DQ +I +I+G PT E WP M +M + +
Sbjct: 160 SYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVI 219
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+ PQ N + FS PQD LDL + + +D R T T++LQ YF +P
Sbjct: 220 IKPQTEYMALNYY---FSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQP 271
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 201 bits (511), Expect = 2e-51
Identities = 106/298 (35%), Positives = 173/298 (57%), Gaps = 13/298 (4%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
S F+ L ++G GTY VYK N TG +ALK ++L+ E +G P T+IREI L+++L H
Sbjct: 5 SQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHE 63
Query: 187 NISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSN-----IKHLMKQLFVGLQ 241
NI ++++I ++ N +++ F++M+NDL + +++ + +K+ QL GL
Sbjct: 64 NIVRLYDVIHTE-NKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLA 122
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPEL 300
+ H+ +I+HRD+K NLLI+ RG LK+ DFGLA+ P + ++ V+TLWYR P++
Sbjct: 123 FCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAF---GIPVNTFSSEVVTLWYRAPDV 179
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
L+G+ Y +D W CGC+L E+ G +FPG+N+ +Q + I IMG+P WP + +
Sbjct: 180 LMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKL 239
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDA--LDLASKLLRYDQDTRFTTTEALQHHYF 416
P + + Q +K P D +D LL+ + D R + +AL H +F
Sbjct: 240 PKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 199 bits (505), Expect = 9e-51
Identities = 111/303 (36%), Positives = 174/303 (56%), Gaps = 30/303 (9%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ + ++GEGTYG VYK + TG+++A+K++RLE E +G P T+IREI LL++L HPNI
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI---QFSDSN-IKHLMKQLFVGLQYLH 244
+ ++++ D + + + F+++ DL L SI Q+ DS+ +K + Q+ G+ + H
Sbjct: 64 VSLQDVLMQD-SRLYLIFEFLSMDLKKYL--DSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS-NTNRVITLWYRPPELLLG 303
++++HRD+K NLLID++G +K+ DFGLA+ P T+ V+TLWYR PE+LLG
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAF---GIPIRVYTHEVVTLWYRSPEVLLG 177
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
+ Y VD W G + EL +F G +E+DQ RI +G+P E WP++ +
Sbjct: 178 SARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL--- 234
Query: 364 FMLVPQISKTYKNVF--------FDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+ YKN F + ++ LDL SK+L YD R + AL H Y
Sbjct: 235 --------QDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPY 286
Query: 416 FTN 418
F +
Sbjct: 287 FND 289
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 199 bits (505), Expect = 9e-51
Identities = 110/313 (35%), Positives = 171/313 (54%), Gaps = 24/313 (7%)
Query: 123 QDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
+D++ F L ++GEGTYG V+KA +V ALK +R +++ +G P T +REI ++
Sbjct: 39 RDLQGRFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKD 98
Query: 183 LNHPNISLIHEIIV---------------SDKNTISMGFQYMENDLSG---MLMDKSIQF 224
L H NI + +II S + + M F++++ DL ML +
Sbjct: 99 LQHDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKNLLEMLEPTNSVL 158
Query: 225 SDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPA 284
+ +K M QL L Y H ++IVHRD+K N+L+ + G +KI DFGLA+ S P+
Sbjct: 159 PPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNF---SFPS 215
Query: 285 SN-TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRIL 343
N T+ V+TLWYRPPE+LLG+ Y +D W GC+ E+ + +FPG E+ Q +I
Sbjct: 216 RNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIF 275
Query: 344 SIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDT 403
I+G+P ++ WP + P + + PQ K + +E S + + LD+ ++LRY +
Sbjct: 276 EIVGTPNIKSWPGVDSFPHYKAVFPQWPVNLKKL--EETSCLTGNGLDVLREILRYPPER 333
Query: 404 RFTTTEALQHHYF 416
R T AL H YF
Sbjct: 334 RLTAKGALSHRYF 346
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 198 bits (504), Expect = 1e-50
Identities = 116/302 (38%), Positives = 174/302 (57%), Gaps = 19/302 (6%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL---N 184
++Q L +GEG YG VY+A +V TG ++ALK++R+ +G P++++REI LL+QL N
Sbjct: 25 NYQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASN 84
Query: 185 HPNISLIHEIIV----SDKNTISMGFQYMENDLSGML--MDKSIQFSDSNIKHLMKQLFV 238
H NI ++E+ + I + F+++E DLS ++ + KS S I+ L ++L
Sbjct: 85 HANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKS-GMSPPTIQRLSRELLT 143
Query: 239 GLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
G+ +LH +I+HRD+K NLL+ ++G+LKI DFGLAK S T+ V+TLWYR P
Sbjct: 144 GVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK---TYGSEMKLTSVVVTLWYRAP 200
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
E+LL A Y VD W C++ E+F A+FPG++E +Q RI + G PT +QWP+ +
Sbjct: 201 EVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTI 259
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+ PQ F K A DL +K+L YD R + L+H YF
Sbjct: 260 SVA--LEHFPQRHPKRPKDFCPHLCKY---ADDLLNKMLSYDLHLRPSALACLEHDYFQQ 314
Query: 419 EP 420
EP
Sbjct: 315 EP 316
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 197 bits (502), Expect = 2e-50
Identities = 104/299 (34%), Positives = 171/299 (56%), Gaps = 11/299 (3%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
+ F L ++GEGTYG VYK +N T ++A+K++RLE E +G P T++REI LL++L HP
Sbjct: 20 NDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHP 79
Query: 187 NISLIHEIIVSDKNTISMGFQYMENDLSGML--MDKSIQFSDSNIKHLMKQLFVGLQYLH 244
N+ + E ++ +N + + F+++ DL + + K +K Q+ + + H
Sbjct: 80 NVVGL-EAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCH 138
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS-NTNRVITLWYRPPELLLG 303
Q++++HRD+K NLL+DN G +K+ DFGLA+ + P T+ V+TLWYR PE+L+G
Sbjct: 139 QRRVIHRDLKPQNLLVDNNGAIKLADFGLARA---IGIPIRVYTHEVVTLWYRAPEILMG 195
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
A Y VD W GC+ E+ +F G +E+D+ RI ++G+PT +W + +P +
Sbjct: 196 AQRYSMGVDMWSIGCIFAEMATKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDY 255
Query: 364 FMLVPQISKTY-KNVFFDEFS---KVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
P+ + + ++ F+D+ + + A L LL YD R +AL H YF N
Sbjct: 256 KATFPKWRENFLRDKFYDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDN 314
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 194 bits (494), Expect = 2e-49
Identities = 112/314 (35%), Positives = 174/314 (54%), Gaps = 26/314 (8%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP-- 186
++ L +VGEGTYGKVYKA TGKL+ALK+ RLE + +G P T++REI LLQ L+
Sbjct: 4 YEKLEKVGEGTYGKVYKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQSIY 63
Query: 187 --NISLIHEIIVSDKNTIS--------MGFQYMENDLSGMLMDKSIQFSD------SNIK 230
+ + +I S +T+S + F+Y++ DL + D + S+ S ++
Sbjct: 64 IVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLDTDLKKFI-DSHRKGSNPRPLEASLVQ 122
Query: 231 HLMKQLFVGLQYLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNR 289
M QLF G+ + H ++HRD+K NLL+D ++G LKI D GL++ T + T+
Sbjct: 123 RFMFQLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLK--AYTHE 180
Query: 290 VITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSP 349
++TLWYR PE+LLG+T Y VD W GC+ E+ A+FPG +E Q I ++G+P
Sbjct: 181 IVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTP 240
Query: 350 TLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTE 409
T +QWP ++ + W + K + + +DL +++L+Y+ R +
Sbjct: 241 TEQQWPGVMALRDWHV----YPKWEPQDLSRAVPSLSPEGIDLLTQMLKYNPAERISAKA 296
Query: 410 ALQHHYFTNEPKPQ 423
AL H YF + K Q
Sbjct: 297 ALDHPYFDSLDKSQ 310
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 194 bits (493), Expect = 2e-49
Identities = 111/298 (37%), Positives = 168/298 (56%), Gaps = 16/298 (5%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTG---KLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++++ L +VGEGTYG VYKA ++ G +++ALK++RLE E +G P T+IREI LL++L
Sbjct: 6 ANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKEL 65
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGML--MDKSIQFSDSNIKHLMKQLFVGLQ 241
NI +++I+ SD + + + F++++ DL + + K +K M QL G+
Sbjct: 66 KDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIA 125
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
Y H +I+HRD+K NLLI+ GNLK+ DFGLA+ + T+ ++TLWYR PE+L
Sbjct: 126 YCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFG--VPLRAYTHEIVTLWYRAPEVL 183
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
LG Y VD W GC+ E+ IF G +E+DQ +I ++G+P WP ++ +P
Sbjct: 184 LGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLP 243
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQ---DALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ PQ + D VP +DL KLL YD R + A H YF
Sbjct: 244 DFKPSFPQWRRK------DLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYF 295
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 194 bits (493), Expect = 2e-49
Identities = 110/305 (36%), Positives = 172/305 (56%), Gaps = 21/305 (6%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNH 185
+ ++ L +GEG+Y VYK + T + +ALK +RL QE +G P T+IRE LL++L H
Sbjct: 189 QEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRL-QEEEGAPFTAIREASLLKELKH 247
Query: 186 PNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
NI +H+I V + T++ F+Y+ DLS + N++ + QL GL Y H+
Sbjct: 248 SNIVTLHDI-VHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHK 306
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
++++HRD+K NLLI + G LK+ DFGLA+ + S S + V+TLWYRPP++LLG+T
Sbjct: 307 RRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYS--HEVVTLWYRPPDVLLGST 364
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEV-DQFQRILSIMGSPTLEQWPKMLDMPWWF 364
+Y +D WG GC+ VE+ G FPG + DQ +I ++G+PT + WP + P +
Sbjct: 365 EYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGY- 423
Query: 365 MLVPQISKTYKNVFF------DEFSKVPQ--DALDLASKLLRYDQDTRFTTTEALQHHYF 416
K +K F+ F ++ + +A+ L+ + + R +ALQH YF
Sbjct: 424 -------KPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF 476
Query: 417 TNEPK 421
PK
Sbjct: 477 AQLPK 481
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 192 bits (489), Expect = 7e-49
Identities = 100/293 (34%), Positives = 171/293 (58%), Gaps = 14/293 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
F+ + ++GEGTYG VYK N TG+++A+K++RLE + +G P T+IREI LL++L H NI
Sbjct: 4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENI 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDL----SGMLMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
+ ++++ ++N I + F+++ DL + +DK ++ ++ + Q+ + + H
Sbjct: 64 VCLEDVLM-EENRIYLIFEFLSMDLKKYMDSLPVDKHME--SELVRSYLYQITSAILFCH 120
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS-NTNRVITLWYRPPELLLG 303
+++++HRD+K NLLID G +K+ DFGL + P T+ ++TLWYR PE+LLG
Sbjct: 121 RRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSF---GIPVRIYTHEIVTLWYRAPEVLLG 177
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
+ Y VD W GC+ E+ +F G +E+DQ R+ I+ +PT + WP + +P +
Sbjct: 178 SPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDY 237
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
P S N ++ + + +DL K+L YD R + + L+H YF
Sbjct: 238 KNTFPCWS---TNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 192 bits (487), Expect = 1e-48
Identities = 106/305 (34%), Positives = 174/305 (56%), Gaps = 11/305 (3%)
Query: 134 QVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHE 193
+VGEGTY V+ T + +A+K++++ Q +DG I+++REIK L++ H N+ + +
Sbjct: 16 KVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNVIELVD 75
Query: 194 IIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDI 253
+ S K+ +++ +++++DL ++ DK I F ++IK M L GL ++H + I+HRD+
Sbjct: 76 VF-STKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDL 134
Query: 254 KGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDC 313
K +NLLI + G LK+ DFGL++ D +P+ +++VIT WYRPPEL +G Y VD
Sbjct: 135 KPNNLLISSDGVLKLADFGLSR---DFGTPSHMSHQVITRWYRPPELFMGCRSYGTGVDM 191
Query: 314 WGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML--VPQIS 371
W GC+ EL PG +++DQ I +G+P E M +P + + +P +
Sbjct: 192 WSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKHIPPPN 251
Query: 372 KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPLLLGPEF 431
+ + FS + +DL +L Y+ R T +AL+HHYF+ PKP L P
Sbjct: 252 GGMEAL----FSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPSLLPR- 306
Query: 432 KGSHE 436
KG E
Sbjct: 307 KGGEE 311
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 192 bits (487), Expect = 1e-48
Identities = 108/307 (35%), Positives = 177/307 (57%), Gaps = 36/307 (11%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
++Q + ++GEGTYG VYKA + +G+++A+K++RLE E +G P T+IREI LL+++N N
Sbjct: 3 NYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDEN 62
Query: 188 -----ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFV---- 238
+ L+ I+ ++ + + F++++ DL MD+ + +++ + Q F
Sbjct: 63 NRSNCVRLLD--ILHAESKLYLVFEFLDMDLK-KYMDRISETGATSLDPRLVQKFTYQLV 119
Query: 239 -GLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYR 296
G+ + H ++I+HRD+K NLLID GNLK+ DFGLA+ P N T+ ++TLWYR
Sbjct: 120 NGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSF---GVPLRNYTHEIVTLWYR 176
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PE+LLG+ Y VD W GC+ E+ + +FPG +E+D+ +I ++G+P E WP
Sbjct: 177 APEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIFQVLGTPNEEVWPG 236
Query: 357 MLDMPWWFMLVPQISKTYKNVF-----FDEFSKVP---QDALDLASKLLRYDQDTRFTTT 408
+ + + YK+ F D VP +DA++L S +L YD R +
Sbjct: 237 V-----------TLLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYDPAHRISAK 285
Query: 409 EALQHHY 415
ALQ +Y
Sbjct: 286 RALQQNY 292
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 190 bits (483), Expect = 3e-48
Identities = 109/309 (35%), Positives = 169/309 (54%), Gaps = 19/309 (6%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL-NHP 186
+F+ L +VGEGTYGKVY+A TGK++ALK+ RL ++ +G P T++REI +L+ L P
Sbjct: 13 AFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPSTTLREISILRMLARDP 72
Query: 187 NISLIHEI----IVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNI-----KHLMKQLF 237
++ + ++ K + + F+YM+ D+ + +S + + NI K LM QL
Sbjct: 73 HVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFI--RSFRSTGKNIPTQTIKSLMYQLC 130
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRG-NLKITDFGLAKKLTDVSSPASNTNRVITLWYR 296
G+ + H I+HRD+K NLL+D + LKI D GLA+ T T+ ++TLWYR
Sbjct: 131 KGMAFCHGHGILHRDLKPHNLLMDPKTMRLKIADLGLARAFT--LPMKKYTHEILTLWYR 188
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PE+LLGAT Y VD W GC+ EL AIF G +E+ Q I + G+P E WP
Sbjct: 189 APEVLLGATHYSTAVDMWSVGCIFAELVTNQAIFQGDSELQQLLHIFKLFGTPNEEMWPG 248
Query: 357 MLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ + W + + + + + +DL SK+L+Y+ R + A++H YF
Sbjct: 249 VSTLKNWH----EYPQWKPSTLSSAVPNLDEAGVDLLSKMLQYEPAKRISAKMAMEHPYF 304
Query: 417 TNEPKPQPL 425
+ P+ L
Sbjct: 305 DDLPEKSSL 313
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 190 bits (482), Expect = 4e-48
Identities = 115/326 (35%), Positives = 169/326 (51%), Gaps = 28/326 (8%)
Query: 134 QVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHE 193
++G+GT+G+VYK ++ T + +A+K++ + E+D FPIT+ REI +L++LNH NI + E
Sbjct: 65 KLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIE 124
Query: 194 IIVSDKNTIS------------MGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQ 241
++ I+ M YM DLSG+L + I +IK++M Q+ GL
Sbjct: 125 MVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLN 184
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLA----------KKLTDVSSPASNTNRVI 291
Y+H + +HRDIK +N+LID+ G LK+ DFGLA K S A T+ V+
Sbjct: 185 YIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVV 244
Query: 292 TLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTL 351
T WYR PEL+LG Y VD WG GC+ E F I G ++DQ I ++G+PT
Sbjct: 245 TRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTE 304
Query: 352 EQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSK-VPQDALDLASKLLRYDQDTRFTTTEA 410
E W +P + YK + F K + + LD +LL D R T A
Sbjct: 305 EDWAVARYLPG----AELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSA 360
Query: 411 LQHHYFTNEPKPQPLLLGPEFKGSHE 436
H +F +P P + P + SHE
Sbjct: 361 KHHPWFKEDPLPSEKITLPT-EESHE 385
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 190 bits (482), Expect = 4e-48
Identities = 101/304 (33%), Positives = 166/304 (54%), Gaps = 31/304 (10%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
++ + ++GEGTYG V+KA N ++G+++ALKR+RL+ + +G P +++REI +L++L H N
Sbjct: 3 NYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRN 62
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ +++++ S+ N +++ F+Y + DL + + LM QL GL + H
Sbjct: 63 VVRLYDVVHSE-NKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHH 121
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
++HRD+K NLLI+ G LK+ DFGLA+ + V+TLWYRPP++L GA Y
Sbjct: 122 VLHRDLKPQNLLINTNGTLKLADFGLARAFG--VPVRCFSAEVVTLWYRPPDVLFGAKLY 179
Query: 308 KYEVDCWGCGCLLVELF-AGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP----- 361
+D W GC+ E+ AG +FPG++ DQ +RI +GSP+ + WP + +P
Sbjct: 180 NTSIDMWSAGCIFAEISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPY 239
Query: 362 -------WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHH 414
W +VP ++ + DL KLL + R AL+H
Sbjct: 240 PIYHPTLTWSQIVPNLNSRGR---------------DLLQKLLVCNPAGRIDADAALRHA 284
Query: 415 YFTN 418
YF +
Sbjct: 285 YFAD 288
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 190 bits (482), Expect = 4e-48
Identities = 119/342 (34%), Positives = 181/342 (52%), Gaps = 28/342 (8%)
Query: 102 SAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKL-IALKRL 160
S+ S+S N +KP L + + ++GEGTYG V+ A K IA+K+
Sbjct: 5 SSSRSNSSNSTSEKPEWL-------QQYNLVGKIGEGTYGLVFLARTKTPPKRPIAIKKF 57
Query: 161 RLEQERDGFPITSIREIKLLQQLNHPNI-SLIHEIIVSDKNTISMGFQYMENDLSGMLMD 219
+ ++ DG T+IREI LL++++H N+ L++ I ++ + F Y E DL ++
Sbjct: 58 KQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRH 117
Query: 220 KSIQFSDS----NIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLI----DNRGNLKITDF 271
+ S +K L+ QL GL YLH I+HRD+K SN+L+ + G +KI DF
Sbjct: 118 HRDKVGHSLNTYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADF 177
Query: 272 GLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFP 331
GLA+ P S+ V+T+WYR PELLLG+ Y VD W GC+ EL +F
Sbjct: 178 GLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQ 237
Query: 332 GSN--------EVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQI-SKTYKNVFFDEF 382
G+ ++DQ +I I+G PT+++WP ++++P W V I + Y +V
Sbjct: 238 GAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDSVGLHNV 297
Query: 383 SKVPQ--DALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
+ Q A DL SK+L YD R T ++AL+H YF +P P
Sbjct: 298 VHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYFRMDPLP 339
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 189 bits (481), Expect = 6e-48
Identities = 109/302 (36%), Positives = 162/302 (53%), Gaps = 10/302 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRL---EQERDGFPITSIREIKLL 180
D + L+ +GEG + VYKA + T +++A+K+++ E RDG T++REIK+L
Sbjct: 7 DKTERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKIL 66
Query: 181 QQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGL 240
Q+L H NI + ++ N +S+ F +M+ DL ++ D I + +NIK GL
Sbjct: 67 QELQHENIIGLVDVFGQLSN-VSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGL 125
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+YLH I+HRD+K +NLL+++ G LKI DFGLAK S T+ V+T WYR PEL
Sbjct: 126 EYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFG--SPNRIYTHHVVTRWYRSPEL 183
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
L GA Y VD W GC+L EL PG +++DQ RI S +G+PT +WP + +
Sbjct: 184 LFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKL 243
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+ N+ F+ D + L +L + R + EAL YF N+P
Sbjct: 244 HDYLQFRNFPGTPLDNI----FTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKP 299
Query: 421 KP 422
P
Sbjct: 300 AP 301
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 187 bits (476), Expect = 2e-47
Identities = 104/294 (35%), Positives = 168/294 (56%), Gaps = 13/294 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ + ++GEGTYG V+K N T +++ALKR+RL+++ +G P +++REI LL++L H NI
Sbjct: 4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNI 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ +++ SDK +++ F++ + DL + + + + M QL GL + H +
Sbjct: 64 VRLIDVLHSDKK-LTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNV 122
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS-NTNRVITLWYRPPELLLGATDY 307
+HRD+K NLLI+ G LK+ DFGLA+ P + V+TLWYRPP++L GA Y
Sbjct: 123 LHRDLKPQNLLINKNGELKLADFGLARAF---GIPVKCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 308 KYEVDCWGCGCLLVELF-AGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
+D W GC+L EL AG +FPGS+ +DQ +I ++G+P + WP + + + L
Sbjct: 180 TTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVAL 239
Query: 367 --VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
P I+ + V ++ DL KLL + R + A+QH YFT+
Sbjct: 240 PSFPAITSWSQLV-----PRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 187 bits (474), Expect = 4e-47
Identities = 112/331 (33%), Positives = 185/331 (55%), Gaps = 45/331 (13%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKA--ENVHTGKLIALKRLRLEQ-------ERDGFPITSIR 175
+K ++ + + GTYGKVYKA N + +L A+K+ + E ++ G ++IR
Sbjct: 1 MKDGYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIR 60
Query: 176 EIKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGML----MDKSIQFSDSNIKH 231
E+ L +++ H NI + ++++ D TISM F+Y E+DL ++ ++ Q S +K
Sbjct: 61 EMMLCREIQHENIVSLVQVLLKD-GTISMVFEYAEHDLLQIIHFHSRSRTRQIPPSILKS 119
Query: 232 LMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNR-V 290
++ Q+ G+ YLH+ I+HRD+K +N++I G +KI D GL + + D P +++R V
Sbjct: 120 ILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVV 179
Query: 291 ITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSN-----------EVDQF 339
+T+WYR PELLLGA DY +D W GC+ E+ A + +F G + Q
Sbjct: 180 VTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQM 239
Query: 340 QRILSIMGSPTLEQWPKMLDMP-----------WWFMLVPQISKTYKNVFFDEFSKVPQD 388
RI+ ++G+PT E+WP + + P +W L+PQ +T KN + PQ
Sbjct: 240 LRIMELLGTPTEERWPGLKNYPEYYQLSSFEVRYWNNLLPQWYQTVKN-------RDPQ- 291
Query: 389 ALDLASKLLRYDQDTRFTTTEALQHHYFTNE 419
LDL K+L+YD +R T +AL+H +FT++
Sbjct: 292 GLDLLMKMLQYDPKSRITAKQALEHVFFTSD 322
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 186 bits (473), Expect = 5e-47
Identities = 113/309 (36%), Positives = 169/309 (54%), Gaps = 19/309 (6%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL-NHP 186
+F+ L +VGEGTYGKVY+A TG ++ALK+ RL ++ +G P T++REI +L+ L P
Sbjct: 15 AFEKLEKVGEGTYGKVYRAREKATGMIVALKKTRLHEDEEGVPPTTLREISILRMLARDP 74
Query: 187 NISLIHE----IIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNI-----KHLMKQLF 237
+I + + I K + + F+Y++ DL + +S + + NI K LM QL
Sbjct: 75 HIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFI--RSFRQAGQNIPQNTVKCLMYQLC 132
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRG-NLKITDFGLAKKLTDVSSPASNTNRVITLWYR 296
G+ + H ++HRD+K NLL+D + LKI D GLA+ T T+ ++TLWYR
Sbjct: 133 KGMAFCHGHGVLHRDLKPHNLLMDRKTMTLKIADLGLARAFT--LPMKKYTHEILTLWYR 190
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PE+LLGAT Y VD W GC+ EL AIF G +E+ Q RI ++G+P E WP
Sbjct: 191 APEVLLGATHYSTGVDMWSVGCIFAELVTKQAIFAGDSELQQLLRIFRLLGTPNEEVWPG 250
Query: 357 MLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ + W PQ + + + LDL SK+L Y+ R + +A++H YF
Sbjct: 251 VSKLKDWHE-YPQWKPLSLST---AVPNLDEAGLDLLSKMLEYEPAKRISAKKAMEHPYF 306
Query: 417 TNEPKPQPL 425
+ P L
Sbjct: 307 DDLPDKSSL 315
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 183 bits (464), Expect = 5e-46
Identities = 113/312 (36%), Positives = 169/312 (53%), Gaps = 24/312 (7%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L +VGEGTYGKVYKA TGKL+ALK+ RLE + +G P T++REI LLQ L+ +I
Sbjct: 4 YEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLS-TSI 62
Query: 189 SLIHEIIV-----------SDKNTISMGFQYMENDLSGMLMD-----KSIQFSDSNIKHL 232
++ + V S K+ + + F+Y++ DL + I+ L
Sbjct: 63 YVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKL 122
Query: 233 MKQLFVGLQYLHQQQIVHRDIKGSNLL-IDNRGNLKITDFGLAKKLTDVSSPASNTNRVI 291
M QL G+ + H ++HRD+K NLL + ++ LKI D GL + T S T+ ++
Sbjct: 123 MFQLCKGVAHCHSHGVLHRDLKPQNLLLVKDKELLKIADLGLGRAFTVPLK--SYTHEIV 180
Query: 292 TLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTL 351
TLWYR PE+LLG+T Y VD W GC+ E+ A+FPG +E Q I ++G+PT
Sbjct: 181 TLWYRAPEVLLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTE 240
Query: 352 EQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEAL 411
+QWP + + W + P+ + S PQ +DL +K+L+Y+ R + AL
Sbjct: 241 QQWPGVSTLRDWH-VYPKWEPQDLTLAVPSLS--PQ-GVDLLTKMLKYNPAERISAKTAL 296
Query: 412 QHHYFTNEPKPQ 423
H YF + K Q
Sbjct: 297 DHPYFDSLDKSQ 308
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 183 bits (464), Expect = 5e-46
Identities = 101/289 (34%), Positives = 162/289 (55%), Gaps = 15/289 (5%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L Q+G+GTYG V + TG+ +A+KR++ + ++RE+K L++L+HPNI +
Sbjct: 7 LTQLGDGTYGTVVLGQRKDTGEKVAIKRMK-RKYYSWEEAMNLREVKSLKKLSHPNIVKL 65
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
E+I + +T+ F+YM+ +L M+ D+ + +K ++ Q+ GL ++H+ HR
Sbjct: 66 KEVI-RENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHR 124
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEV 311
D+K NLL +KI DFGLA+ ++ S T+ V T WYR PE+LL +T+Y +
Sbjct: 125 DLKPENLLCSGPDLIKIADFGLAR---EIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTI 181
Query: 312 DCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQIS 371
D W GC++ EL+ +FPGS+EVDQ +I S++G+P + WP + L I
Sbjct: 182 DLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPD------GYRLASMIH 235
Query: 372 KTY----KNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
Y K S+ Q+ LDL +L YD D R T ++L++ YF
Sbjct: 236 FRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 179 bits (454), Expect = 8e-45
Identities = 102/306 (33%), Positives = 170/306 (55%), Gaps = 14/306 (4%)
Query: 117 LALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIRE 176
LA F K ++ + +GEGT+G+V A ALK++ +E++G +T+IRE
Sbjct: 10 LAHRRFTATKMEYEKIRIIGEGTFGQVILARKGRAR--YALKKV--SKEKEGLSVTTIRE 65
Query: 177 IKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQL 236
+++L+ + HP+I + E++V I M F Y DL+ + +S + + S IKH+ Q+
Sbjct: 66 VQVLRAMGHPSIVRLIEVVVEPGGDIYMVFPYFPYDLNRFI--RSNKMTCSEIKHIFYQI 123
Query: 237 FVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYR 296
G+ Y+H + I+HRD+K +N+L+D + N I DFG+A+ T + T ++TLWYR
Sbjct: 124 AQGVCYIHSKGIMHRDLKSANILLDQKLNASIADFGMARYTTKTGA---YTPGMVTLWYR 180
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PE+LLG++ Y Y VD W GC+L E++ G IF GS E+ Q + ++ GS +P
Sbjct: 181 APEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHACGSINENSYPG 240
Query: 357 MLDMPWW-FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+ D+P + +PQ + + + K A++L SK+L D R T + + Y
Sbjct: 241 VQDLPGFRNFRLPQSPRRIEGI----IRKHDASAVELVSKMLCLDPSKRITVEQVVGSKY 296
Query: 416 FTNEPK 421
F +E +
Sbjct: 297 FEHEAR 302
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 176 bits (447), Expect = 5e-44
Identities = 106/299 (35%), Positives = 171/299 (56%), Gaps = 22/299 (7%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTG-KLIALKRLRLEQERDGFPITSIREIKLLQQLN--- 184
++ +A++GEG YGKV+KA ++ G + +ALKR+R++ +G P+++IRE+ +L+ L
Sbjct: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72
Query: 185 HPNISLIHEIIV---SDKNT-ISMGFQYMENDLSGMLMDKSIQ--FSDSNIKHLMKQLFV 238
HPN+ + ++ +D+ T +++ F++++ DL+ L DK + IK +M QL
Sbjct: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYL-DKVPEPGVPTETIKDMMFQLLR 131
Query: 239 GLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
GL +LH ++VHRD+K N+L+ + G +K+ DFGLA+ S + T+ V+TLWYR P
Sbjct: 132 GLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLAR---IYSFQMALTSVVVTLWYRAP 188
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
E+LL + Y VD W GC+ E+F +F GS++VDQ +IL ++G P E WP+ +
Sbjct: 189 EVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDV 247
Query: 359 DMPWWFMLVPQISKTYKNVF-FDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+P K V DE K DL K L ++ R + AL H YF
Sbjct: 248 ALPRQAFHSKSAQPIEKFVTDIDELGK------DLLLKCLTFNPAKRISAYSALSHPYF 300
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 176 bits (446), Expect = 6e-44
Identities = 101/296 (34%), Positives = 160/296 (53%), Gaps = 18/296 (6%)
Query: 134 QVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHE 193
+VGEGTY VY TG+ IA+K ++ + +DG +++IRE+K LQ++ HPN+ + +
Sbjct: 12 KVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELID 71
Query: 194 IIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDI 253
I ++ N +++ +++ DL ++ DKSI F+ ++IK M G+ + H+ I+HRD+
Sbjct: 72 IFMAYDN-LNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDL 130
Query: 254 KGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN---TNRVITLWYRPPELLLGATDYKYE 310
K +NLL G +K+ DFGLA+ + PA + T+ V+T WYR PELL GA Y
Sbjct: 131 KPNNLLFSPDGQIKVADFGLARAI-----PAPHEILTSNVVTRWYRAPELLFGAKHYTSA 185
Query: 311 VDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQI 370
+D W G + EL PG N+VDQ + +G+PT WP++ FM ++
Sbjct: 186 IDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSS----FMTYNKL 241
Query: 371 SKTYKNVFFDEFSK----VPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
+ Y DE K + ALD +L + R+T + L+ YF P P
Sbjct: 242 -QIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP 296
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 171 bits (433), Expect = 2e-42
Identities = 102/283 (36%), Positives = 166/283 (58%), Gaps = 12/283 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ + QVGEG +G+VYK+ G + A+K++ +++E GFP T+IREIKL + + + +I
Sbjct: 4 YENIKQVGEGAFGQVYKSRRTSDGAVFAIKKMPVDRET-GFPFTAIREIKLCKSVINKHI 62
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ EI+ ++ I + +YM DL+G+L + + S I+ + QL + +H +
Sbjct: 63 IGLDEIVF-EEGFIFVVLEYMPYDLTGLLASGA-KLSTDQIRSITSQLIEAVSSMHGMGL 120
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
VHRDIK SN+L+D G LK+TDFGL ++++ + TNRV TLWYR PELLLG T Y
Sbjct: 121 VHRDIKPSNILLDCHGMLKLTDFGLTREISGMM-----TNRVCTLWYRAPELLLGETSYS 175
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLE-QWPKMLDMPWWF--- 364
+VD W GC+++E+ G + GS+EV Q + I +G P + +W +LD+ +
Sbjct: 176 LKVDAWSVGCIMLEMRLGRPPYRGSDEVSQIKLIFEELGIPQDKYKWSDLLDVDIYSKSR 235
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTT 407
I++ Y ++F +E KV L L S+ ++R+ T
Sbjct: 236 STEEIIAERYGHLFDEEELKVLSGFLCLTSRKRLSVANSRYFT 278
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 170 bits (431), Expect = 4e-42
Identities = 112/326 (34%), Positives = 182/326 (55%), Gaps = 40/326 (12%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKL--------IALKRLRLEQERDGFPITSIREIKLLQQL 183
L +VG+GT+G V++A N T ++ +A+KR++ ++ ++RE+K L ++
Sbjct: 7 LKEVGDGTFGNVWRAVNKQTNEVGTEVFYVQVAIKRMK-KKYFSWEECVNLREVKSLSRM 65
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
NHPNI + E+I + + + F+YME +L ++ D+ F++S+I++ Q+F GL Y+
Sbjct: 66 NHPNIVKLKEVI-RENDILYFVFEYMECNLYQLMKDRPKHFAESDIRNWCFQVFQGLSYM 124
Query: 244 HQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLG 303
HQ+ HRD+K NLL+ ++ +KI D GLA+++ D S P T V T WYR PE+LL
Sbjct: 125 HQRGYFHRDLKPENLLV-SKDVIKIADLGLAREI-DSSPPY--TEYVSTRWYRAPEVLLQ 180
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
+ Y +VD W G ++ EL + +FPG++E D+ +I S++GSPT E W + L++
Sbjct: 181 SYVYTSKVDMWAMGAIMAELLSLRPLFPGASEADEIYKICSVIGSPTEETWLEGLNL--- 237
Query: 364 FMLVPQISKTYKNVFFDEFSKV---------PQDALDLASKLLRYDQDTRFTTTEALQHH 414
+ N F +F V DA++L +L +D R TT EALQH
Sbjct: 238 --------ASVINYQFPQFPGVHLSSVMPYASADAVNLIERLCSWDPCNRPTTAEALQHP 289
Query: 415 YFTN----EPKPQPLLLGPEFKGSHE 436
+F + P +P L P +GS E
Sbjct: 290 FFQSCYYIPPSLRPKLSEP--RGSLE 313
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 169 bits (428), Expect = 8e-42
Identities = 87/287 (30%), Positives = 169/287 (58%), Gaps = 15/287 (5%)
Query: 134 QVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHE 193
++G+GT+G+V A+ + TG +A+KR++ ++ S+RE+K L++LNHPNI + E
Sbjct: 50 RLGDGTFGEVMLAKKIDTGDRVAIKRMK-KKFYSWEEAMSLREVKSLKKLNHPNIIKLRE 108
Query: 194 IIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDI 253
+I + + + F++M+ +L ++ D+ F +S I++++ Q+ GL ++H+ HRD+
Sbjct: 109 VI-RENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDM 167
Query: 254 KGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDC 313
K N++ + +KI DFGLA+ ++ S T+ V T WYR PE+LL +T Y +D
Sbjct: 168 KPENIMCNGTELVKIADFGLAR---EIRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDM 224
Query: 314 WGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKT 373
W GC++ EL+ +FPG++E+DQ +I+SI+G+P ++WP+ + L ++
Sbjct: 225 WALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPE------GYQLASAMNFR 278
Query: 374 YKNVFFDEFSKV----PQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
++ V +V ++ + L ++ ++ + R ++L++ YF
Sbjct: 279 FQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYF 325
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 168 bits (426), Expect = 1e-41
Identities = 91/293 (31%), Positives = 164/293 (55%), Gaps = 17/293 (5%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ + Q+G+GTYG V ++ +G+LIA+K+++ + ++RE+K L++LNH N+
Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNHANV 62
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+I + + + F+YM+ +L ++ +++ F +S I+++M Q+ GL ++H+
Sbjct: 63 VKLKEVI-RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGF 121
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
HRD+K NLL +KI DFGLA+ ++ S T+ V T WYR PE+LL +T+Y
Sbjct: 122 FHRDLKPENLLCMGPELVKIADFGLAR---EIRSKPPYTDYVSTRWYRAPEVLLRSTNYS 178
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP-----WW 363
+D W GC++ E++ +FPG++E+D +I ++G+P WP+ + W
Sbjct: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
VP KT +A+ L +L++D R T ++AL++ YF
Sbjct: 239 PQCVPNNLKTL-------IPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 168 bits (425), Expect = 2e-41
Identities = 100/301 (33%), Positives = 167/301 (55%), Gaps = 22/301 (7%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDG---FPITSIREIKLLQQL 183
S ++P+A++G G YG VYKA + H+G +ALK +R+ G PI+++RE+ LL++L
Sbjct: 4 SRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRL 63
Query: 184 N---HPNISLIHEIIVSDKNT----ISMGFQYMENDLSGMLMDKSIQ--FSDSNIKHLMK 234
HPN+ + ++ + + +++ F++++ DL L DK+ IK LM+
Sbjct: 64 EAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYL-DKAPPPGLPAETIKDLMR 122
Query: 235 QLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLW 294
Q GL +LH IVHRD+K N+L+ + G +K+ DFGLA+ S + T V+TLW
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLAR---IYSYQMALTPVVVTLW 179
Query: 295 YRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQW 354
YR PE+LL +T Y VD W GC+ E+F +F G++E DQ +I ++G P + W
Sbjct: 180 YRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDW 238
Query: 355 PKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHH 414
P+ + +P P+ + ++V ++ + L ++L ++ R + ALQH
Sbjct: 239 PRDVSLPRG-AFPPRGPRPVQSV----VPEMEESGAQLLLEMLTFNPHKRISAFRALQHS 293
Query: 415 Y 415
Y
Sbjct: 294 Y 294
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 167 bits (422), Expect = 4e-41
Identities = 102/299 (34%), Positives = 168/299 (56%), Gaps = 20/299 (6%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLE----QERDGFPITSIREIKLL 180
V ++ L ++G+GT G VYKA N+ T +++A+K+++ + +E ++RE+K L
Sbjct: 8 VMCRYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEE-----CVNLREVKAL 62
Query: 181 QQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGL 240
++LNHP+I + EI V + N + F+ M+++L ++ ++ FS+ I+ M Q+ GL
Sbjct: 63 RKLNHPHIIKLKEI-VREHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGL 121
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
++H+ HRD+K NLL+ N LKI DFGLA+ +V+S T V T WYR PE+
Sbjct: 122 AHMHKNGYFHRDLKPENLLVTNN-ILKIADFGLAR---EVASMPPYTEYVSTRWYRAPEV 177
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
LL ++ Y VD W G +L EL+A +FPG +E+DQ +I ++G P +P+ +
Sbjct: 178 LLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPDWTTFPEAKSI 237
Query: 361 PWWFMLVPQISKTY--KNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
+ IS T + D +A+DL ++L +D R T EAL H +F+
Sbjct: 238 ----SRIMSISHTEFPQTRIADLLPNAAPEAIDLINRLCSWDPLKRPTADEALNHPFFS 292
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 167 bits (422), Expect = 4e-41
Identities = 95/294 (32%), Positives = 164/294 (55%), Gaps = 14/294 (4%)
Query: 131 PLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISL 190
P+ +G G G V A + T + +A+K++ + ++REIKLL+ +H NI
Sbjct: 62 PIRPIGRGACGIVCSAVDSETNEKVAIKKITQVFDNTIEAKRTLREIKLLRHFDHENIVA 121
Query: 191 IHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIK----HLMKQLFVGLQYLHQQ 246
I ++I+ + S Y+ N+L + ++++ K + M Q+ GL+Y+H
Sbjct: 122 IRDVILPPQRD-SFEDVYIVNELMEFDLYRTLKSDQELTKDHGMYFMYQILRGLKYIHSA 180
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN--TNRVITLWYRPPELLLGA 304
++HRD+K SNLL+ + +LKI DFGLA+ ++P SN T V+T WYR PELLLG+
Sbjct: 181 NVLHRDLKPSNLLLSTQCDLKICDFGLAR-----ATPESNLMTEYVVTRWYRAPELLLGS 235
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
+DY +D W GC+ +E+ +FPG ++V+Q + +L ++G+P+ E+ + + +
Sbjct: 236 SDYTAAIDVWSVGCIFMEIMNREPLFPGKDQVNQLRLLLELIGTPSEEELGSLSEYAKRY 295
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+ Q+ + F ++F VP A+DL K+L +D R + EAL H Y ++
Sbjct: 296 --IRQLPTLPRQSFTEKFPNVPPLAIDLVEKMLTFDPKQRISVKEALAHPYLSS 347
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 166 bits (419), Expect = 9e-41
Identities = 91/293 (31%), Positives = 163/293 (55%), Gaps = 17/293 (5%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ + Q+G+GTYG V ++ +G+LIA+K+++ + + RE+K L++LNH N+
Sbjct: 4 YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNQREVKSLKKLNHANV 62
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+I + + + F+YM+ +L ++ +++ F +S I+++M Q+ GL ++H+
Sbjct: 63 VKLKEVI-RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKLGF 121
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
HRD+K NLL +KI DFGLA+ ++ S T+ V T WYR PE+LL +T+Y
Sbjct: 122 FHRDLKPENLLCMGPELVKIADFGLAR---EIRSKPPYTDYVSTRWYRAPEVLLRSTNYS 178
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP-----WW 363
+D W GC++ E++ +FPG++E+D +I ++G+P WP+ + W
Sbjct: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
VP KT +A+ L +L++D R T ++AL++ YF
Sbjct: 239 PQCVPNNLKTL-------IPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 164 bits (416), Expect = 2e-40
Identities = 99/300 (33%), Positives = 159/300 (53%), Gaps = 9/300 (3%)
Query: 122 FQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQ 181
F+ + P+ +G G G V A N TG+ +A+K++ + ++REIKLL+
Sbjct: 68 FEVSRKYVPPIRPIGRGACGIVCAAVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLR 127
Query: 182 QLNHPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLF 237
++H N+ I +I+ + N + + ++ M+ DL +L SD + L+ QL
Sbjct: 128 HMDHENVITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQ-CRFLVYQLL 186
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRP 297
GL+Y+H I+HRD++ SN+L++++ LKI DFGLA+ +D T V+T WYR
Sbjct: 187 RGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFM---TEYVVTRWYRA 243
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
PELLL ++Y +D W GC+L E+ G +FPG + V Q + I ++GSP
Sbjct: 244 PELLLNCSEYTAAIDIWSVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSL-GF 302
Query: 358 LDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
L V Q+ + K F F K+P A+DL ++L +D + R + EAL H Y +
Sbjct: 303 LRSDNARRYVRQLPRYPKQQFAARFPKMPTTAIDLLERMLVFDPNRRISVDEALGHAYLS 362
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 164 bits (415), Expect = 3e-40
Identities = 101/312 (32%), Positives = 162/312 (51%), Gaps = 19/312 (6%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L +G G YG V AE +G +A+K+ + + RE++LL+ + H NI +
Sbjct: 38 LTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDL 97
Query: 192 HEIIVSDKNTISMGFQY-----MENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
++ ++N + Y M DLS +L K + +D +I+ L+ Q+ GL+Y+H
Sbjct: 98 LDVFTPNENVNDIEDVYFVSMLMGADLSNIL--KIQRLNDDHIQFLVYQILRGLKYIHSA 155
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
I+HRD+K SN+ ++ LKI DFGLA++ + + T V T WYR PE++L
Sbjct: 156 DIIHRDLKPSNIAVNEDCELKILDFGLARQ-----TDSEMTGYVATRWYRAPEIMLNWMH 210
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC+L EL G +FPGS+ +DQ RI+S+ G+P E++ K +
Sbjct: 211 YTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPD-EEFLKKISSEEARNY 269
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF------TNEP 420
+ + K + F F++ A+DL K+L D D R T EA++H Y T+EP
Sbjct: 270 IRNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAYHDETDEP 329
Query: 421 KPQPLLLGPEFK 432
+ + L + +
Sbjct: 330 IAEEMDLNDDVR 341
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 164 bits (414), Expect = 3e-40
Identities = 95/293 (32%), Positives = 165/293 (55%), Gaps = 17/293 (5%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ + Q+G+GTYG V ++ +G+L+A+KR++ + ++RE+K L++LNH N+
Sbjct: 4 YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMK-RKFYSWDECMNLREVKSLKKLNHANV 62
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+I + + + F+YM+ +L ++ D++ F +S I+++M Q+ GL ++H+
Sbjct: 63 IKLKEVI-RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGF 121
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
HRD+K NLL +KI DFGLA++L S T+ V T WYR PE+LL ++ Y
Sbjct: 122 FHRDMKPENLLCMGPELVKIADFGLARELR---SQPPYTDYVSTRWYRAPEVLLRSSVYS 178
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK----MLDMPWWF 364
+D W G ++ EL+ +FPG++EVD+ +I ++G+P WP+ M + F
Sbjct: 179 SPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRF 238
Query: 365 -MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
VP KT +A+ L +++L +D R T ++AL+H YF
Sbjct: 239 PQCVPINLKTL-------IPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 164 bits (414), Expect = 3e-40
Identities = 98/313 (31%), Positives = 164/313 (52%), Gaps = 16/313 (5%)
Query: 110 NIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGF 169
NIFG F+ P+ +G+G YG V A N T + +A+K++ +
Sbjct: 50 NIFGN------IFEVTAKYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKID 103
Query: 170 PITSIREIKLLQQLNHPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLMDKSIQFS 225
++REIKLL+ ++H NI I +II N + + ++ M+ DL ++ S
Sbjct: 104 AKRTLREIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQA-LS 162
Query: 226 DSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS 285
+ + ++ + Q+ GL+Y+H ++HRD+K SNLL++ +LKI DFGLA+ S
Sbjct: 163 EEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARV---TSESDF 219
Query: 286 NTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSI 345
T V+T WYR PELLL ++DY +D W GC+ +EL +FPG + V Q + ++ +
Sbjct: 220 MTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMEL 279
Query: 346 MGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRF 405
+G+P+ E+ + + + + Q+ + D+F V A+DL K+L +D R
Sbjct: 280 IGTPSEEELEFLNENAKRY--IRQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRI 337
Query: 406 TTTEALQHHYFTN 418
T +AL H Y +
Sbjct: 338 TVLDALAHPYLNS 350
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 163 bits (412), Expect = 6e-40
Identities = 96/307 (31%), Positives = 158/307 (51%), Gaps = 11/307 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V +Q L+ VG G YG V A + TG +A+K+L + + RE++LL+ +
Sbjct: 19 EVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHM 78
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ---FSDSNIKHLMKQLFVGL 240
H N+ + ++ ++ Y+ L G ++ ++ +D +++ L+ Q+ GL
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+Y+H I+HRD+K SNL ++ LKI DFGLA+ D T V T WYR PE+
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDD-----EMTGYVATRWYRAPEI 193
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
+L Y VD W GC++ EL G +FPG++ +DQ + IL ++G+P E K +
Sbjct: 194 MLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELL-KKISS 252
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--N 418
+ +++ K F + F A+DL K+L D D R T +AL H YF +
Sbjct: 253 ESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYH 312
Query: 419 EPKPQPL 425
+P +P+
Sbjct: 313 DPDDEPV 319
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 162 bits (410), Expect = 1e-39
Identities = 102/335 (30%), Positives = 170/335 (50%), Gaps = 23/335 (6%)
Query: 104 GDSHSRNIFGKKPLALISFQDVKSSFQP-LAQVGEGTYGKVYKAENVHTGKLIALKRLRL 162
G S +IFG S ++ S ++P + +G G YG V + T +L+A+K++
Sbjct: 19 GQFISYDIFG-------SLFEITSKYRPPIIPIGRGAYGIVCSVLDTETNELVAMKKIAN 71
Query: 163 EQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLM 218
+ ++REIKLL+ L+H NI I +++ + + + + M+ DL ++
Sbjct: 72 AFDNHMDAKRTLREIKLLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQIIR 131
Query: 219 DKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLT 278
S+ + ++ + QL GL+Y+H I+HRD+K SNLL++ +LKI DFGLA+
Sbjct: 132 SNQ-SLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLARP-- 188
Query: 279 DVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQ 338
S T V+T WYR PELLL ++DY +D W GC+ +EL +FPG + V Q
Sbjct: 189 -TSENDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQ 247
Query: 339 FQRILSIMGSPTLEQ--WPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKL 396
+ + ++G+PT + D + +P + FS V A+DL ++
Sbjct: 248 MRLLTELLGTPTESDLGFTHNEDAKRYIRQLPNFP---RQPLAKLFSHVNPMAIDLVDRM 304
Query: 397 LRYDQDTRFTTTEALQHHYFT--NEPKPQPLLLGP 429
L +D + R T +AL H Y ++P +P+ P
Sbjct: 305 LTFDPNRRITVEQALNHQYLAKLHDPNDEPICQKP 339
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 161 bits (408), Expect = 2e-39
Identities = 106/317 (33%), Positives = 165/317 (51%), Gaps = 19/317 (5%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
DV + L +GEG YG V A + +A+K++ E + ++REI++L +
Sbjct: 37 DVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRF 95
Query: 184 NHPNISLIHEII----VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H N+ I +I+ + + + ME DL +L KS Q S+ +I + + Q+ G
Sbjct: 96 RHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLL--KSQQLSNDHICYFLYQILRG 153
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-----TNRVITLW 294
L+Y+H ++HRD+K SNLLI+ +LKI DFGLA+ ++ P + T V T W
Sbjct: 154 LKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR----IADPEHDHTGFLTEYVATRW 209
Query: 295 YRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQW 354
YR PE++L + Y +D W GC+L E+ + IFPG + +DQ IL I+GSP+ E
Sbjct: 210 YRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDL 269
Query: 355 PKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHH 414
+++M L SKT K + F K ALDL ++L ++ + R T EAL H
Sbjct: 270 NCIINMKARNYLQSLPSKT-KVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHP 328
Query: 415 YFTN--EPKPQPLLLGP 429
Y +P +P+ P
Sbjct: 329 YLEQYYDPTDEPVAEEP 345
>Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 452
Score = 160 bits (406), Expect = 3e-39
Identities = 94/293 (32%), Positives = 153/293 (52%), Gaps = 28/293 (9%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L ++GEG +G V+KA++V TG++IALK++ L + DGFP ++REIK LQ++ +
Sbjct: 7 LGRIGEGAHGIVFKAKHVETGEIIALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQ 66
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
+ + + F++M +DL+ ++ + + +K ++ L G+ + H IVHR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEV 311
D+K +NLLI G LKI DFGLA+ V SP G+ Y ++V
Sbjct: 127 DLKPANLLISASGQLKIADFGLAR----VFSPD------------------GSRLYTHQV 164
Query: 312 DCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW--FMLVPQ 369
GC++ EL G+ +FPG N+++Q +L I+G+P + WP++ ++P + Q
Sbjct: 165 ATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQ 224
Query: 370 ISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
+ + V D V ALDL + L Y R ++AL H YF P P
Sbjct: 225 VPMPLEEVLPD----VSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLP 273
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 160 bits (406), Expect = 3e-39
Identities = 110/320 (34%), Positives = 161/320 (49%), Gaps = 35/320 (10%)
Query: 134 QVGEGTYGKVYKA--ENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
+VG GTYG VYKA ++ K ALK++ E G +++ REI LL++L HPN+ +
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL 81
Query: 192 HEIIVSDKNT-ISMGFQYMENDLSGMLM--------DKSIQFSDSNIKHLMKQLFVGLQY 242
++ +S + + + F Y E+DL ++ K +Q S +K L+ Q+ G+ Y
Sbjct: 82 QKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHY 141
Query: 243 LHQQQIVHRDIKGSNLLI----DNRGNLKITDFGLAKKLTDVSSPASNTNRVI-TLWYRP 297
LH ++HRD+K +N+L+ RG +KI D G A+ P ++ + V+ T WYR
Sbjct: 142 LHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRA 201
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNE---------VDQFQRILSIMGS 348
PELLLGA Y +D W GC+ EL IF E DQ RI S+MG
Sbjct: 202 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGF 261
Query: 349 PTLEQWPKMLDMPWWFMLVPQISK-TYKN---VFFDEFSKVPQDA--LDLASKLLRYDQD 402
P + W + MP + L + TY N + + E KV D+ L KLL D
Sbjct: 262 PADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPT 321
Query: 403 TRFTTTEALQHHYFTNEPKP 422
R T+ +ALQ YF +P P
Sbjct: 322 KRITSEQALQDPYFQEDPLP 341
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 160 bits (406), Expect = 3e-39
Identities = 88/213 (41%), Positives = 134/213 (62%), Gaps = 14/213 (6%)
Query: 133 AQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIH 192
A +G GTYG+VY+A + T + +ALKR+RL E++G P T++REI +L++L+H NI +
Sbjct: 8 ALIGSGTYGEVYEAIDTETKEKVALKRIRLN-EKEGMPGTALREISILKKLSHRNIISLV 66
Query: 193 EIIVSDKNTISMGFQYMENDLS---GMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIV 249
II +D ++M F +++ +L GM K NI L+ QL G+ YLH+ +V
Sbjct: 67 SIIHTDA-LLTMVFPFIDYELKKYIGMNTGK-------NIMELVNQLICGVHYLHRMNVV 118
Query: 250 HRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKY 309
HRD+K N+L+ + G LKI DFGL++ L P S+ V+TLWYR PELL+G+T Y++
Sbjct: 119 HRDLKPQNILVTSDGVLKIADFGLSRSLEIRVPPYSS--EVVTLWYRSPELLMGSTSYRF 176
Query: 310 EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRI 342
VD W GC++ E+ +FPG ++ +Q I
Sbjct: 177 YVDIWSLGCIIYEMITLEPLFPGESKENQLTLI 209
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 160 bits (405), Expect = 4e-39
Identities = 107/345 (31%), Positives = 175/345 (50%), Gaps = 55/345 (15%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
D+ S ++ + +GEG YG V A + +G +A+K+++ ++ F +IREIKLL+
Sbjct: 8 DIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKL-FVTRTIREIKLLRYF 66
Query: 184 N-HPNI----SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS---DSNIKHLMKQ 235
+ H NI + + + N + + + ME DL ++ +++ FS D ++++ Q
Sbjct: 67 HEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQ 126
Query: 236 LFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-----TNRV 290
+ L+ +H Q++HRDIK SNLL+++ +LK+ DFGLA+ L S T V
Sbjct: 127 ILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYV 186
Query: 291 ITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPT 350
T WYR PE++L +Y +D W CGC+L E+ +G +FPG + Q IL ++G+P+
Sbjct: 187 ATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPS 246
Query: 351 LEQW---------------PKMLDMPW---WFMLVPQISKTYKNVFFDEFSKVPQDALDL 392
E + P +PW W SKT N D +DL
Sbjct: 247 FEDFNQIKSKRAKEYIANLPMRPPLPWETVW-------SKTDLN----------PDMIDL 289
Query: 393 ASKLLRYDQDTRFTTTEALQHHYF------TNEPKPQPLLLGPEF 431
K+L+++ D R + EAL+H Y ++EP+ PL L EF
Sbjct: 290 LDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYPPLNLDDEF 334
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 160 bits (405), Expect = 4e-39
Identities = 95/310 (30%), Positives = 156/310 (49%), Gaps = 17/310 (5%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V +Q L+ VG G YG V A + TG +A+K+L + + RE++LL+ +
Sbjct: 19 EVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHM 78
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ---FSDSNIKHLMKQLFVGL 240
H N+ + ++ ++ Y+ L G ++ ++ +D +++ L+ Q+ GL
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+Y+H I+HRD+K SNL ++ LKI DFGLA+ D T V T WYR PE+
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDD-----EMTGYVATRWYRAPEI 193
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSP---TLEQWPKM 357
+L Y VD W GC++ EL G +FPG++ ++Q Q+I+ + G+P + + P
Sbjct: 194 MLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSH 253
Query: 358 LDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
+ L + NVF A+DL K+L D D R T +AL H YF
Sbjct: 254 EARNYIQSLTQMPKMNFANVFIG----ANPLAVDLLEKMLVLDSDKRITAAQALAHAYFA 309
Query: 418 --NEPKPQPL 425
++P +P+
Sbjct: 310 QYHDPDDEPV 319
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 160 bits (404), Expect = 5e-39
Identities = 100/320 (31%), Positives = 165/320 (51%), Gaps = 21/320 (6%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ S FQ + +GEG YG V A + TG+++A+K++ ++ F + ++REIK+L+
Sbjct: 8 NISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIE-PFDKPLFALRTLREIKILKHF 66
Query: 184 NHPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H NI I I D N + + + M+ DL ++ + + SD +I++ + Q
Sbjct: 67 KHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQML--SDDHIQYFIYQTLRA 124
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKL----TDVSSPASN----TNRVI 291
++ LH ++HRD+K SNLLI++ +LK+ DFGLA+ + D S P T V
Sbjct: 125 VKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVA 184
Query: 292 TLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTL 351
T WYR PE++L + Y +D W CGC+L ELF IFPG + Q I I+G+P
Sbjct: 185 TRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHS 244
Query: 352 EQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEAL 411
+ + ++ P + + F +V +DL ++L +D R T EAL
Sbjct: 245 DNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEAL 304
Query: 412 QHHYF------TNEPKPQPL 425
+H Y +EP+ +P+
Sbjct: 305 EHPYLQTYHDPNDEPEGEPI 324
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 160 bits (404), Expect = 5e-39
Identities = 102/301 (33%), Positives = 153/301 (49%), Gaps = 43/301 (14%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+FQ + ++GEGTYG VYKA N TG+++ALK++RL+ E +G P T+IREI LL++LNHPN
Sbjct: 3 NFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPN 62
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKS--IQFSDSNIKHLMKQLFVGLQYLHQ 245
I + ++I ++ N + + F+++ DL MD S IK + QL GL + H
Sbjct: 63 IVKLLDVIHTE-NKLYLVFEFLHQDLK-KFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
+++HRD+K NLLI+ G +K+ DFGLA+ +
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFG-----------------------VPVR 157
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y +EV A+FPG +E+DQ RI +G+P WP + MP +
Sbjct: 158 TYTHEV-------------TRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-- 202
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
P K + F + +D L S++L YD R + AL H +F + KP P
Sbjct: 203 -KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPYKRISAKAALAHPFFQDVTKPVPH 261
Query: 426 L 426
L
Sbjct: 262 L 262
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 159 bits (402), Expect = 8e-39
Identities = 108/320 (33%), Positives = 159/320 (48%), Gaps = 35/320 (10%)
Query: 134 QVGEGTYGKVYKAENVH--TGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
+VG GTYG VYKA+ K ALK++ E G +++ REI LL++L HPN+ +
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL 81
Query: 192 HEIIVSDKNT-ISMGFQYMENDLSGMLM--------DKSIQFSDSNIKHLMKQLFVGLQY 242
++ +S + + + F Y E+DL ++ K +Q +K L+ Q+ G+ Y
Sbjct: 82 QKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHY 141
Query: 243 LHQQQIVHRDIKGSNLLI----DNRGNLKITDFGLAKKLTDVSSPASNTNRVI-TLWYRP 297
LH ++HRD+K +N+L+ RG +KI D G A+ P ++ + V+ T WYR
Sbjct: 142 LHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRA 201
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNE---------VDQFQRILSIMGS 348
PELLLGA Y +D W GC+ EL IF E DQ RI ++MG
Sbjct: 202 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGF 261
Query: 349 PTLEQWPKMLDMPWWFMLVPQISK-TYKN---VFFDEFSKVPQD--ALDLASKLLRYDQD 402
P + W + MP L+ + TY N + + E KV D A L KLL D
Sbjct: 262 PADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPI 321
Query: 403 TRFTTTEALQHHYFTNEPKP 422
R T+ +A+Q YF +P P
Sbjct: 322 KRITSEQAMQDPYFLEDPLP 341
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 159 bits (402), Expect = 8e-39
Identities = 95/318 (29%), Positives = 159/318 (49%), Gaps = 35/318 (11%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V Q L VG G YG V A + + +A+K+L + + RE++LL+ L
Sbjct: 19 EVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHL 78
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ---FSDSNIKHLMKQLFVGL 240
H N+ + ++ + Y+ L G ++ ++ SD +++ L+ QL GL
Sbjct: 79 KHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGL 138
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+Y+H I+HRD+K SN+ ++ L+I DFGLA++ + T V T WYR PE+
Sbjct: 139 KYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADE-----EMTGYVATRWYRAPEI 193
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
+L Y VD W GC++ EL G A+FPGS+ +DQ +RI+ ++G+P+ E
Sbjct: 194 MLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPE-------- 245
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQD------------ALDLASKLLRYDQDTRFTTT 408
++ +IS + + +PQ A+DL ++L D D R +
Sbjct: 246 -----VLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA 300
Query: 409 EALQHHYFT--NEPKPQP 424
EAL H YF+ ++P+ +P
Sbjct: 301 EALAHAYFSQYHDPEDEP 318
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 158 bits (400), Expect = 1e-38
Identities = 92/304 (30%), Positives = 158/304 (51%), Gaps = 10/304 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ + + L +G G +G V A++ TG +A+K++ + RE+KLL+ L
Sbjct: 15 EITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKHL 74
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
H NI + +I +S I + + DL +L + ++ I++ + Q+ GL+++
Sbjct: 75 RHENIISLSDIFISPFEDIYFVTELLGTDLHRLLTSRPLE--TQFIQYFLYQILRGLKFV 132
Query: 244 HQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLG 303
H ++HRD+K SN+LI+ +LKI DFGLA+ + P T V T +YR PE++L
Sbjct: 133 HSAGVIHRDLKPSNILINENCDLKICDFGLAR----IQDPQM-TGYVSTRYYRAPEIMLT 187
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y EVD W GC+ E+ G +FPG + V+QF I ++G+P +E +
Sbjct: 188 WQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVIETICSKN-T 246
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPK 421
V + + K F ++F DA+DL K+L +D R + +AL H+Y ++P
Sbjct: 247 LRFVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRISAADALAHNYLAPYHDPT 306
Query: 422 PQPL 425
+P+
Sbjct: 307 DEPV 310
>Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 366
Score = 158 bits (400), Expect = 1e-38
Identities = 98/288 (34%), Positives = 153/288 (53%), Gaps = 21/288 (7%)
Query: 132 LAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
L ++GEGTYG V+KA+N T +++ALK +RL+ DG P +++REI LL++L H NI +
Sbjct: 78 LEKIGEGTYGTVFKAKNWETHEIVALKWVRLDDNDDGVPSSALREICLLKELKHKNIVRL 137
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
H+++ SDK +++ F++ L + +K + QL GL + H + ++ R
Sbjct: 138 HDLLHSDKK-LTLVFKFCHQHLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLRR 196
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEV 311
D+K NLLI+ G LK+ DFGL++ I + Y + GA Y +
Sbjct: 197 DLKPQNLLINRNGELKLADFGLSRAFG------------IPICY----VFFGAKLYSTSI 240
Query: 312 DCWGCGCLLVELF-AGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQI 370
D W GC+ EL AG +FPG++ DQ +RI ++G T EQWP M +P + L P
Sbjct: 241 DLWSAGCIFAELANAGWPLFPGNDVDDQLKRIFWLLGMLTKEQWPSMTKLP-DYKLYPLY 299
Query: 371 SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
T V + K+ DL LL+ + + EALQ+ YF++
Sbjct: 300 PATTSLV--NIVPKLSATGRDLLQNLLKCNPCQCISAEEALQYPYFSD 345
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 158 bits (400), Expect = 1e-38
Identities = 95/305 (31%), Positives = 157/305 (51%), Gaps = 23/305 (7%)
Query: 134 QVGEGTYGKVYKAEN--------VHTGKLI-----ALKRLRLEQERDGFPITSIREIKLL 180
++GEGTY +Y V +G I A+K+++ + G I++IREIK L
Sbjct: 9 RLGEGTYAVIYLGYRALPQDKPLVSSGTRIEDVPVAIKKIKPTKYTQGHEISAIREIKSL 68
Query: 181 QQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGL 240
++++ + + + V DK + + +Y+E +L ++ + +IK + + G+
Sbjct: 69 KRIDSKYVVRLIDTFVYDK-CVHIVLEYVETNLENVIRNSDKIIMPGDIKAWILMVLRGV 127
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
H+ I+HRDIK +N+LI + G +K+ DFGL + + + +P + +T WYR PEL
Sbjct: 128 YECHRLFIIHRDIKPNNILITSEGMVKLADFGLTRGIGNRMTP-----QAVTRWYRAPEL 182
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
L+G+ DY VD W GC+ ELF +F G ++ Q I +G+P +WP + +
Sbjct: 183 LMGSRDYGSPVDMWSVGCVFAELFLRVPLFAGDTDIQQLDMIFRALGTPVEREWPGVSTL 242
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
P F+ Q K N FS DALDL KLL + R + +A++H YF + P
Sbjct: 243 P-EFLDFQQYPKASLNGL---FSAASSDALDLLEKLLTLNPCNRISCDDAIKHPYFKSSP 298
Query: 421 KPQPL 425
P P+
Sbjct: 299 PPTPI 303
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 158 bits (399), Expect = 2e-38
Identities = 92/292 (31%), Positives = 153/292 (51%), Gaps = 9/292 (3%)
Query: 131 PLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISL 190
P+ +G G YG V A N T + +A+K++ + ++REIKLL ++H N+
Sbjct: 35 PIEPIGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAKRTLREIKLLSHMDHDNVIK 94
Query: 191 IHEIIVSDKNT----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
I +II + + + ++ M+ DL ++ +D + ++ + Q+ GL+Y+H
Sbjct: 95 IKDIIELPEKERFEDVYIVYELMDTDLHQIIRSTQT-LTDDHCQYFLYQILRGLKYIHSA 153
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRD+K SNL+++ +LKI DFGLA+ + T V+T WYR PELLL +++
Sbjct: 154 NVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETEIM---TEYVVTRWYRAPELLLNSSE 210
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y +D W GC+ +E+ +FPG + V Q + I ++GSP + L
Sbjct: 211 YTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPD-DSDLDFLRSDNARKY 269
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
V Q+ K F ++F + ALDLA K+L +D R T EAL+ Y +
Sbjct: 270 VKQLPHVQKQSFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQPYLAS 321
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 157 bits (398), Expect = 2e-38
Identities = 97/313 (30%), Positives = 164/313 (51%), Gaps = 15/313 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ ++ + +G+G YG V A + +G +A+K++ F + ++REIKLL+
Sbjct: 34 ELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIH-PFNHPVFCLRTLREIKLLRHF 92
Query: 184 NHPNISLIHEII----VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H NI I +I+ + + + + ME DL ++ +S SD + ++ Q+
Sbjct: 93 RHENIISILDILPPPSYQELEDVYIVQELMETDLYRVI--RSQPLSDDHCQYFTYQILRA 150
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLT-DVSSPASNTNRVITLWYRPP 298
L+ +H +VHRD+K SNLL++ +LK+ DFGLA+ T +P T V T WYR P
Sbjct: 151 LKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAP 210
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
E++L +Y +D W GC+L E+ + +FPG + Q IL+I+G+PT++ + + +
Sbjct: 211 EIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSR-I 269
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF-- 416
+ + T K F F + DA+DL KLL ++ D R T EAL+H Y
Sbjct: 270 KSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALKHPYVAA 329
Query: 417 ----TNEPKPQPL 425
++EP P+
Sbjct: 330 YHDASDEPTASPM 342
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 157 bits (398), Expect = 2e-38
Identities = 99/299 (33%), Positives = 156/299 (52%), Gaps = 9/299 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V + F+ L VGEG YG V K + T +++A+K+ + +E + T++RE+K+L+ L
Sbjct: 8 NVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTL 67
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
NI + E + + + F+Y+E ++ +L + +K + QL + +
Sbjct: 68 KQENIVELKEAF-RRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWC 126
Query: 244 HQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLG 303
H+ IVHRDIK NLLI + LK+ DFG A+ L++ + A+ T V T WYR PELLLG
Sbjct: 127 HKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSE-GNNANYTEYVATRWYRSPELLLG 185
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
A Y VD W GC+L EL G +FPG +E+DQ I ++G EQ P +
Sbjct: 186 A-PYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRF 244
Query: 364 FML-VPQIS--KTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNE 419
L P ++ ++ + + + V LDL LL+ D R+ T + L H F +
Sbjct: 245 HGLRFPAVNHPQSLERRYLGILNSV---LLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 157 bits (398), Expect = 2e-38
Identities = 101/315 (32%), Positives = 162/315 (51%), Gaps = 15/315 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
DV + L+ +GEG YG V A + +A+K++ E + ++REIK+L +
Sbjct: 20 DVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRF 78
Query: 184 NHPNISLIHEII----VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H NI I++II + + + ME DL +L K+ S+ +I + + Q+ G
Sbjct: 79 RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRG 136
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLT-DVSSPASNTNRVITLWYRPP 298
L+Y+H ++HRD+K SNLL++ +LKI DFGLA+ D T V T WYR P
Sbjct: 137 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 196
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
E++L + Y +D W GC+L E+ + IFPG + +DQ + IL I+GSP+ E ++
Sbjct: 197 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLKHILGILGSPSQEDLNCII 256
Query: 359 DMPW--WFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
++ + + +P +K N F ALDL K+L ++ R +AL H Y
Sbjct: 257 NLKARNYLLSLPHKNKVPWNRL---FPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 313
Query: 417 TN--EPKPQPLLLGP 429
+P +P+ P
Sbjct: 314 EQYYDPSDEPIAEAP 328
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 157 bits (398), Expect = 2e-38
Identities = 93/315 (29%), Positives = 164/315 (51%), Gaps = 15/315 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ + + P+ +G G YG V + N T + +A+K++ E + ++RE+KLL+ +
Sbjct: 27 EIDTKYVPIKPIGRGAYGVVCSSINRETNERVAIKKIHNVFENRVDALRTLRELKLLRHV 86
Query: 184 NHPNISLIHEIIV----SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H N+ + ++++ S + + ++ M+ DL ++ S SD + K+ + QL G
Sbjct: 87 RHENVIALKDVMLPANRSSFKDVYLVYELMDTDLH-QIIKSSQSLSDDHCKYFLFQLLRG 145
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L+YLH I+HRD+K NLL++ +LKI DFGLA+ T + T V+T WYR PE
Sbjct: 146 LKYLHSANILHRDLKPGNLLVNANCDLKICDFGLAR--TSQGNEQFMTEYVVTRWYRAPE 203
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLL +Y +D W GC+ E+ IFPG+ ++Q + I++++GS E + +D
Sbjct: 204 LLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQ-ESDIRFID 262
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF--- 416
P + + + + + + A+DL ++L +D R + T+AL H Y
Sbjct: 263 NPKARRFIKSLPYSRGTHLSNLYPQANPLAIDLLQRMLVFDPTKRISVTDALLHPYMAGL 322
Query: 417 ----TNEPKPQPLLL 427
+N P P+ L
Sbjct: 323 FDPGSNPPAHVPISL 337
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 157 bits (397), Expect = 3e-38
Identities = 93/295 (31%), Positives = 151/295 (50%), Gaps = 16/295 (5%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G YG V A + +G+ +A+K+L + + F + RE+ LL+ + H N+ + ++
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDV 90
Query: 195 IVSDKNTIS-----MGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIV 249
+ + + +M+ DL ++ ++FS+ I++L+ Q+ GL+Y+H +V
Sbjct: 91 FTPASSLRNFYDFYLVMPFMQTDLQKIM---GMEFSEEKIQYLVYQMLKGLKYIHSAGVV 147
Query: 250 HRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKY 309
HRD+K NL ++ LKI DFGLA+ + A T V+T WYR PE++L Y
Sbjct: 148 HRDLKPGNLAVNEDCELKILDFGLARH-----ADAEMTGYVVTRWYRAPEVILSWMHYNQ 202
Query: 310 EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQ 369
VD W GC++ E+ G +F G + +DQ +IL + G P E K+ D +
Sbjct: 203 TVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKA-AKSYIQS 261
Query: 370 ISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQP 424
+ +T + F F + A DL K+L D D R T +AL H +F EP P
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFF--EPFRDP 314
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 157 bits (397), Expect = 3e-38
Identities = 101/315 (32%), Positives = 161/315 (51%), Gaps = 15/315 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
DV + L+ +GEG YG V A + +A+K++ E + ++REIK+L +
Sbjct: 20 DVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRF 78
Query: 184 NHPNISLIHEII----VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H NI I++II + + + ME DL +L K+ S+ +I + + Q+ G
Sbjct: 79 RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLL--KTQHLSNDHICYFLYQILRG 136
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLT-DVSSPASNTNRVITLWYRPP 298
L+Y+H ++HRD+K SNLL++ +LKI DFGLA+ D T V T WYR P
Sbjct: 137 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAP 196
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
E++L + Y +D W GC+L E+ + IFPG + +DQ IL I+GSP+ E ++
Sbjct: 197 EIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCII 256
Query: 359 DMPW--WFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
++ + + +P +K N F ALDL K+L ++ R +AL H Y
Sbjct: 257 NLKARNYLLSLPHKNKVPWNRL---FPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYL 313
Query: 417 TN--EPKPQPLLLGP 429
+P +P+ P
Sbjct: 314 EQYYDPSDEPIAEAP 328
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 157 bits (396), Expect = 4e-38
Identities = 88/248 (35%), Positives = 147/248 (58%), Gaps = 15/248 (6%)
Query: 173 SIREIKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHL 232
++RE+K L+++NHPNI + E+I + + + F+YME +L ++ D+ F++++IK+
Sbjct: 13 NLREVKSLRRMNHPNIVKLKEVI-RENDILYFVFEYMECNLYQLMKDRQKLFAEADIKNW 71
Query: 233 MKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVIT 292
Q+F GL Y+HQ+ HRD+K NLL+ ++ +KI DFGLA+ +V+S T V T
Sbjct: 72 CFQVFQGLSYMHQRGYFHRDLKPENLLV-SKDIIKIADFGLAR---EVNSSPPFTEYVST 127
Query: 293 LWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLE 352
WYR PE+LL + Y +VD W G ++ EL + IFPG++E D+ +I S++G+PT E
Sbjct: 128 RWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEADEIYKICSVIGTPTEE 187
Query: 353 QWPKMLDMP----WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTT 408
W + L++ + F +P + + +DA++L +L +D +R T
Sbjct: 188 TWLEGLNLANTINYQFPQLPGVPLS------SLMPSASEDAINLIERLCSWDPSSRPTAA 241
Query: 409 EALQHHYF 416
E LQH +F
Sbjct: 242 EVLQHPFF 249
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 156 bits (395), Expect = 5e-38
Identities = 102/345 (29%), Positives = 173/345 (49%), Gaps = 18/345 (5%)
Query: 92 GPRAMGSSAESAGDSHSR-NIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVH 150
G ++ + G S+ + N++G F+ + PL +G G YG V A N
Sbjct: 11 GDQSSSKGVATHGGSYVQYNVYGNL------FEVSRKYVPPLRPIGRGAYGIVCAATNSE 64
Query: 151 TGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSDK----NTISMGF 206
TG+ +A+K++ + ++REIKLL+ ++H N+ + +II + N + + +
Sbjct: 65 TGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVY 124
Query: 207 QYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNL 266
+ M+ DL ++ +D + + + QL GL+Y+H ++HRD+K SNLL++ +L
Sbjct: 125 ELMDTDLHQIIRSNQ-PLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDL 183
Query: 267 KITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAG 326
K+ DFGLA+ ++ T V+T WYR PELLL ++Y +D W GC+L E
Sbjct: 184 KLGDFGLARTKSETDFM---TEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTR 240
Query: 327 AAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVP 386
+FPG + V Q + I ++GSP + L V Q+ + + F F +
Sbjct: 241 EPLFPGKDYVHQLRLITELIGSPD-DSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMS 299
Query: 387 QDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPKPQPLLLGP 429
A+DL K+L +D R T EAL H Y ++ +P+ + P
Sbjct: 300 AGAVDLLEKMLVFDPSRRITVDEALCHPYLAPLHDINEEPVCVRP 344
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 156 bits (395), Expect = 5e-38
Identities = 105/320 (32%), Positives = 154/320 (47%), Gaps = 35/320 (10%)
Query: 134 QVGEGTYGKVYKAENVHT--GKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN-ISL 190
+VG GTYG VYKA+ T GK ALK++ + G +++ REI LL++L H N I+L
Sbjct: 103 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITL 158
Query: 191 IHEIIVSDKNTISMGFQYMENDL--------SGMLMDKSIQFSDSNIKHLMKQLFVGLQY 242
I + + + + Y E+DL + K + +K L+ Q+ G+ Y
Sbjct: 159 IRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHY 218
Query: 243 LHQQQIVHRDIKGSNLLI----DNRGNLKITDFGLAKKLTDVSSPASNTNRVI-TLWYRP 297
LH ++HRD+K +N+L+ + RG +KI D G A+ P ++ + V+ T WYR
Sbjct: 219 LHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRA 278
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNE---------VDQFQRILSIMGS 348
PELLLGA Y +D W GC+ EL IF E DQ RI ++MG
Sbjct: 279 PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGF 338
Query: 349 PTLEQWPKMLDMPWWFMLVPQISK-TYKNVFFDEFS-----KVPQDALDLASKLLRYDQD 402
P + W + MP L + TY ++ K A L KLL D +
Sbjct: 339 PQDKDWEDIKKMPEHHTLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPN 398
Query: 403 TRFTTTEALQHHYFTNEPKP 422
R T+ +A+Q YF EP+P
Sbjct: 399 KRITSEQAMQDQYFQEEPQP 418
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 155 bits (392), Expect = 1e-37
Identities = 89/296 (30%), Positives = 159/296 (53%), Gaps = 8/296 (2%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ + + P+ +G G YG V + N + + +A+K++ E + ++RE+KLL+ L
Sbjct: 27 EIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAIKKIHNVFENRIDALRTLRELKLLRHL 86
Query: 184 NHPNISLIHEIIVSDKNT----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H N+ + ++++++ + + ++ M+ DL ++ + S+ + ++ + QL G
Sbjct: 87 RHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQIIKSSQV-LSNDHCQYFLFQLLRG 145
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L+Y+H I+HRD+K NLL++ +LKI DFGLA+ T + T V+T WYR PE
Sbjct: 146 LKYIHSANILHRDLKPGNLLVNANCDLKICDFGLAR--TSNTKGQFMTEYVVTRWYRAPE 203
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLL +Y +D W GC+ EL +FPG+ ++Q + I++I+GS E+ + +D
Sbjct: 204 LLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQR-EEDLEFID 262
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
P + + + F + A+DL K+L D R + TEALQH Y
Sbjct: 263 NPKAKRYIESLPYSPGISFSRLYPGANVLAIDLLQKMLVLDPSKRISVTEALQHPY 318
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 154 bits (390), Expect = 2e-37
Identities = 80/235 (34%), Positives = 130/235 (55%), Gaps = 1/235 (0%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
S ++ L ++GEG +G V+KA ++ K +A+K++ L+ + + ++REIK LQ
Sbjct: 7 SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSE 66
Query: 187 NISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
I I +I D +S+ +Y + L L + S ++ Q+F G+ YLH+
Sbjct: 67 YILDIIDIY-PDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEA 125
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRDIK +NLLI + LKI DFGLA+ + +V T WYR PE+L G+
Sbjct: 126 GLMHRDIKPANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQK 185
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
Y VD W GC++ E+ G +F G+ +++Q I+ +GSP L QWP++ +P
Sbjct: 186 YGTGVDMWAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLP 240
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 154 bits (389), Expect = 3e-37
Identities = 97/305 (31%), Positives = 165/305 (53%), Gaps = 29/305 (9%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G++G V++A+ + TG+ +A+K++ ++ RE++L++ ++HPN+ +
Sbjct: 46 VGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKN------RELQLMRVMDHPNVVCLKHC 99
Query: 195 IVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYL 243
S D+ +++ +Y+ L +L +S +N +K M Q+F GL Y+
Sbjct: 100 FFSTTSKDELFLNLVMEYVPESLYRVLK----HYSSANQRMPLVYVKLYMYQIFRGLAYI 155
Query: 244 HQQQ-IVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
H + HRD+K NLL+D + +KI DFG AK+L +N + + + +YR PEL+
Sbjct: 156 HNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLV---KGEANISYICSRFYRAPELI 212
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
GAT+Y +D W GC+L EL G +FPG N VDQ I+ ++G+PT E+ + ++
Sbjct: 213 FGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREE-IRCMNPH 271
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPK 421
+ PQI + F + ++P +A+D AS+LL+Y R T EA H +F +
Sbjct: 272 YTDFRFPQIKAHPWHKIFHK--RMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDELRE 329
Query: 422 PQPLL 426
P L
Sbjct: 330 PNARL 334
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 152 bits (385), Expect = 8e-37
Identities = 96/309 (31%), Positives = 159/309 (51%), Gaps = 17/309 (5%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V++ ++ L VG G YG V A + TG +A+K+L + + F + RE++LL+ +
Sbjct: 22 EVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHM 81
Query: 184 NHPNISLIHEIIVSDKNT-----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFV 238
H N+ + ++ D+ + +M DL G LM K + + I+ L+ Q+
Sbjct: 82 RHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDL-GKLM-KHEKLGEDRIQFLVYQMLK 139
Query: 239 GLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
GL+Y+H I+HRD+K NL ++ LKI DFGLA++ + + T V+T WYR P
Sbjct: 140 GLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQ-----ADSEMTGYVVTRWYRAP 194
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
E++L Y VD W GC++ E+ G +F GS+ +DQ + I+ + G+P E + + L
Sbjct: 195 EVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAE-FVQRL 253
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+ + + K F + A++L K+L D + R T EAL H YF +
Sbjct: 254 QSDEAKNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFES 313
Query: 419 ----EPKPQ 423
E +PQ
Sbjct: 314 LHDTEDEPQ 322
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 152 bits (385), Expect = 8e-37
Identities = 100/361 (27%), Positives = 173/361 (47%), Gaps = 46/361 (12%)
Query: 90 PRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENV 149
P GP A +A ++N+ K + DV ++ + +G G YG V A
Sbjct: 17 PPGP-VKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRR 75
Query: 150 HTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEII-----VSDKNTISM 204
TG+ +A+K++ + ++RE+K+L+ H NI I +I+ + ++ +
Sbjct: 76 LTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYV 135
Query: 205 GFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRG 264
ME+DL ++ S + ++++ + QL GL+Y+H Q++HRD+K SNLL++
Sbjct: 136 VLDLMESDLH-QIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENC 194
Query: 265 NLKITDFGLAKKLTDVSSPASN----TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLL 320
LKI DFG+A+ L +SPA + T V T WYR PEL+L +Y +D W GC+
Sbjct: 195 ELKIGDFGMARGLC--TSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIF 252
Query: 321 VELFAGAAIFPGSNEVDQFQRILSIMGSPT---------------LEQWPKMLDMPWWFM 365
E+ A +FPG N V Q Q I+ ++G+P+ ++ P +PW +
Sbjct: 253 GEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETV 312
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPKPQ 423
+ + AL L ++LR++ R + AL+H + ++P +
Sbjct: 313 ----------------YPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDE 356
Query: 424 P 424
P
Sbjct: 357 P 357
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 152 bits (384), Expect = 1e-36
Identities = 100/312 (32%), Positives = 167/312 (53%), Gaps = 14/312 (4%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTG--KLIALKRLRLEQERDGFPITSIREIKLLQQ 182
V+ +F+ + ++G+G YG V A NV + + +A+K++ + ++REIKLL
Sbjct: 17 VEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIH 76
Query: 183 L-NHPNISLIHEIIVSDK---NTISMGFQYMENDLSGMLMDKSIQ-FSDSNIKHLMKQLF 237
NH NI+ I+++ + + N + + + ME DL+ ++ KS Q +D++ + + Q+
Sbjct: 77 FRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAII--KSGQPLTDAHFQSFIYQIL 134
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTD--VSSPASNTNRVITLWY 295
GL+Y+H ++HRD+K NLL++ LKI DFGLA+ ++ +P T V T WY
Sbjct: 135 CGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWY 194
Query: 296 RPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWP 355
R PE++L + Y +D W GC+L EL G +F G + V Q IL +G+P E+
Sbjct: 195 RAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPD-EETL 253
Query: 356 KMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+ V + K F F K ALDL +KLL +D + R + +AL+H Y
Sbjct: 254 SHISSSRAQEYVRSLPKQRPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEHPY 313
Query: 416 FT--NEPKPQPL 425
++P +P+
Sbjct: 314 LAVWHDPSDEPV 325
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 152 bits (384), Expect = 1e-36
Identities = 96/326 (29%), Positives = 160/326 (48%), Gaps = 26/326 (7%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ +Q L VG G YG+V KA T +A+K+L + + RE++LL+ +
Sbjct: 20 EIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHM 79
Query: 184 NHPNISLIHEII--------VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQ 235
+H N+ + +I + + + + M+ DL+ ++ + + SD +++ L+ Q
Sbjct: 80 DHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHL--SDDHVQFLVYQ 137
Query: 236 LFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN--TNRVITL 293
+ GL+Y+H ++HRD+K SN+ ++ L+I DFGLA+ P N T V T
Sbjct: 138 ILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-------PTENEMTGYVATR 190
Query: 294 WYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQ 353
WYR PE++L Y VD W GC++ EL +FPG++ + Q I+ ++G+P E
Sbjct: 191 WYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEF 250
Query: 354 WPKMLD---MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEA 410
K+ + L P +++KNV F A+DL K+L D + R T EA
Sbjct: 251 LKKISSESARSYIQSLPPMKGRSFKNV----FKNANPLAIDLLEKMLELDAEKRITAEEA 306
Query: 411 LQHHYFTNEPKPQPLLLGPEFKGSHE 436
L H Y +P P + S E
Sbjct: 307 LSHPYLEKYAEPSVEQTSPPYDHSFE 332
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 152 bits (383), Expect = 1e-36
Identities = 100/361 (27%), Positives = 174/361 (47%), Gaps = 46/361 (12%)
Query: 90 PRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENV 149
P GP + A +A ++N+ K + DV ++ + +G G YG V A
Sbjct: 17 PPGPVKV-EPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRR 75
Query: 150 HTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEII-----VSDKNTISM 204
TG+ +A+K++ + ++RE+K+L+ H NI I +I+ + ++ +
Sbjct: 76 LTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYV 135
Query: 205 GFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRG 264
ME+DL ++ S + ++++ + QL GL+Y+H Q++HRD+K SNLL++
Sbjct: 136 VLDLMESDLH-QIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENC 194
Query: 265 NLKITDFGLAKKLTDVSSPASN----TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLL 320
LKI DFG+A+ L +SPA + T V T WYR PEL+L +Y +D W GC+
Sbjct: 195 ELKIGDFGMARGLC--TSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIF 252
Query: 321 VELFAGAAIFPGSNEVDQFQRILSIMGSPT---------------LEQWPKMLDMPWWFM 365
E+ A +FPG N V Q Q I+ ++G+P+ ++ P +PW +
Sbjct: 253 GEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETV 312
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPKPQ 423
+ + AL L ++LR++ R + AL+H + ++P +
Sbjct: 313 ----------------YPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDE 356
Query: 424 P 424
P
Sbjct: 357 P 357
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 152 bits (383), Expect = 1e-36
Identities = 101/314 (32%), Positives = 164/314 (52%), Gaps = 13/314 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V + L+ +GEG YG V A + T +A+K++ E F ++REIK+L +
Sbjct: 91 EVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKIS-PFEHQTFCQRTLREIKILNRF 149
Query: 184 NHPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H NI I EII S+ I + ME DL +L K+ + S+ ++ + + Q+ G
Sbjct: 150 KHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLL--KTQKLSNDHVCYFLYQILRG 207
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN--TNRVITLWYRP 297
L+Y+H ++HRD+K SNLL++ +LKI DFGLA+ +TD + + T V T WYR
Sbjct: 208 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VTDPQTDHTGFLTEYVATRWYRA 266
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
PE++L + Y +D W GC+L E+ + +FPG + +DQ IL+++GSP+ +
Sbjct: 267 PEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCI 326
Query: 358 LDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
++ L+ K K + + ALDL K+L ++ R +AL H Y
Sbjct: 327 INDKARSYLISLPHKP-KQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLE 385
Query: 418 N--EPKPQPLLLGP 429
+P +P+ P
Sbjct: 386 QYYDPGDEPVCEEP 399
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 152 bits (383), Expect = 1e-36
Identities = 101/314 (32%), Positives = 164/314 (52%), Gaps = 13/314 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V + L+ +GEG YG V A + T +A+K++ E F ++REIK+L +
Sbjct: 23 EVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKIS-PFEHQTFCQRTLREIKILNRF 81
Query: 184 NHPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H NI I EII S+ I + ME DL +L K+ + S+ ++ + + Q+ G
Sbjct: 82 KHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLL--KTQKLSNDHVCYFLYQILRG 139
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN--TNRVITLWYRP 297
L+Y+H ++HRD+K SNLL++ +LKI DFGLA+ +TD + + T V T WYR
Sbjct: 140 LKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-VTDPQTDHTGFLTEYVATRWYRA 198
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
PE++L + Y +D W GC+L E+ + +FPG + +DQ IL+++GSP+ +
Sbjct: 199 PEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKHYLDQLNLILAVVGSPSNADLQCI 258
Query: 358 LDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
++ L+ K K + + ALDL K+L ++ R +AL H Y
Sbjct: 259 INDKARSYLISLPHKP-KQPWARLYPGADPRALDLLDKMLTFNPHNRIDIEQALAHPYLE 317
Query: 418 N--EPKPQPLLLGP 429
+P +P+ P
Sbjct: 318 QYYDPGDEPVCEEP 331
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 151 bits (382), Expect = 2e-36
Identities = 87/305 (28%), Positives = 159/305 (51%), Gaps = 13/305 (4%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ + + P+ +G G YG V + N T + +A+K++ E + ++RE+KLL+ +
Sbjct: 27 EIDTKYVPIKPIGRGAYGVVCSSINSETNERVAIKKIHNVFENRIDALRTLRELKLLRHV 86
Query: 184 NHPNISLIHEIIVSDKN----TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H N+ + ++++ + + ++ M++DL+ ++ S SD + K+ + QL G
Sbjct: 87 RHENVISLKDVMLPTHRYSFRDVYLVYELMDSDLN-QIIKSSQSLSDDHCKYFLFQLLRG 145
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L+YLH I+HRD+K NLL++ +LKI DFGLA+ T V+T WYR PE
Sbjct: 146 LKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTYEQFM-----TEYVVTRWYRAPE 200
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWP-KML 358
LLL +Y +D W GC+ E+ IFPG+ ++Q + I++++GS + W + +
Sbjct: 201 LLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQ--QDWDLQFI 258
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
D + + + F + A+DL ++L +D R + ++AL H Y
Sbjct: 259 DNQKARRFIKSLPFSKGTHFSHIYPHANPLAIDLLQRMLVFDPTKRISVSDALLHPYMEG 318
Query: 419 EPKPQ 423
+P+
Sbjct: 319 LLEPE 323
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 151 bits (381), Expect = 2e-36
Identities = 95/310 (30%), Positives = 158/310 (50%), Gaps = 26/310 (8%)
Query: 115 KPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSI 174
KPL + FQ ++ +G+G YG VY+ ++H GK ALK++ + + +G P + +
Sbjct: 31 KPLTMKDFQIHQA-------LGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVL 83
Query: 175 REIKLLQQLN---HPNI----SLIHEII-VSDKNTISMGFQYMENDLSGMLMDKSIQFSD 226
REI +++ L HPNI S+ H++ V I+M + + DL L + +
Sbjct: 84 REITVMKHLARKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPE 143
Query: 227 SNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN 286
KH+ Q+ L +LH I+HRD+K N+L++ +K+ DFGL+K + S+ +
Sbjct: 144 QQAKHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSK---EYSNTTAF 200
Query: 287 TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIM 346
T V+TLWYR PE+LL + Y VD W GC++ E++ +F G NE +Q I M
Sbjct: 201 TTLVVTLWYRSPEVLL-QSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKM 259
Query: 347 GSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFS-KVPQDALDLASKLLRYDQDTRF 405
G+P + WP ++ Y+ + S ++ + A++ + LRYD R
Sbjct: 260 GTPVGKDWPSE------SVIARDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRL 313
Query: 406 TTTEALQHHY 415
+ AL H +
Sbjct: 314 SARGALSHPF 323
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 151 bits (381), Expect = 2e-36
Identities = 97/306 (31%), Positives = 164/306 (52%), Gaps = 31/306 (10%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G++G V++A+ + TG+ +A+K++ ++ RE++L++ ++HPN+ +
Sbjct: 78 VGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN------RELQLMRLMDHPNVVSLKHC 131
Query: 195 IVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYL 243
S D+ +++ +Y+ L +L ++ SN +K Q+F GL Y+
Sbjct: 132 FFSTTTRDELFLNLVMEYVPETLYRVLK----HYTSSNQRMPIFYVKLYTYQIFRGLAYI 187
Query: 244 HQQQ-IVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
H + HRD+K NLL+D + K+ DFG AK L +N + + + +YR PEL+
Sbjct: 188 HTAPGVCHRDVKPQNLLVDPLTHQCKLCDFGSAKVLV---KGEANISYICSRYYRAPELI 244
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
GAT+Y +D W GC+L EL G +FPG N VDQ I+ ++G+PT E+ + ++
Sbjct: 245 FGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREE-IRCMNPN 303
Query: 362 WWFMLVPQI-SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+ PQI + + VF ++P +A+DLAS+LL+Y R T EA H +F
Sbjct: 304 YTDFRFPQIKAHPWHKVF---HKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELR 360
Query: 421 KPQPLL 426
+P L
Sbjct: 361 EPNARL 366
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 151 bits (381), Expect = 2e-36
Identities = 97/306 (31%), Positives = 164/306 (52%), Gaps = 31/306 (10%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G++G V++A+ + TG+ +A+K++ ++ RE++L++ ++HPN+ +
Sbjct: 76 VGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKN------RELQLMRPMDHPNVISLKHC 129
Query: 195 IVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYL 243
S D+ +++ +Y+ L +L ++ SN +K Q+F GL Y+
Sbjct: 130 FFSTTSRDELFLNLVMEYVPETLYRVLR----HYTSSNQRMPIFYVKLYTYQIFRGLAYI 185
Query: 244 HQQQ-IVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
H + HRD+K NLL+D + +K+ DFG AK L N + + + +YR PEL+
Sbjct: 186 HTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLV---KGEPNISYICSRYYRAPELI 242
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
GAT+Y +D W GC+L EL G +FPG N VDQ I+ ++G+PT E+ + ++
Sbjct: 243 FGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREE-IRCMNPN 301
Query: 362 WWFMLVPQI-SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEP 420
+ PQI + + VF ++P +A+DLAS+LL+Y R T EA H +F
Sbjct: 302 YTDFRFPQIKAHPWHKVF---HKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELR 358
Query: 421 KPQPLL 426
+P L
Sbjct: 359 EPNARL 364
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 150 bits (380), Expect = 3e-36
Identities = 92/304 (30%), Positives = 151/304 (49%), Gaps = 10/304 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ + + L VG G +G V A + T + +A+K++ + RE+KLL+ L
Sbjct: 18 EITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHL 77
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
H N+ + +I +S I + DL +L + ++ +++ + Q+ GL+Y+
Sbjct: 78 RHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTRPLE--KQFVQYFLYQILRGLKYV 135
Query: 244 HQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLG 303
H ++HRD+K SN+LI+ +LKI DFGLA+ + P T V T +YR PE++L
Sbjct: 136 HSAGVIHRDLKPSNILINENCDLKICDFGLAR----IQDPQM-TGYVSTRYYRAPEIMLT 190
Query: 304 ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y EVD W GC+ E+ G +FPG + V QF I ++GSP + +
Sbjct: 191 WQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSEN-T 249
Query: 364 FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPK 421
V + F + F V DA+DL K+L +D R T +AL H Y ++P
Sbjct: 250 LKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPT 309
Query: 422 PQPL 425
+P+
Sbjct: 310 DEPV 313
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 150 bits (380), Expect = 3e-36
Identities = 116/373 (31%), Positives = 181/373 (48%), Gaps = 36/373 (9%)
Query: 75 GPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQ 134
G +SG G G G G+S G R+ GK + + Q +A
Sbjct: 61 GASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDS-GKVTTVVATLGQGPERSQEVAY 119
Query: 135 -----VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNIS 189
+G G++G VY+A T +L+A+K++ L+ +R RE++++++L+H NI
Sbjct: 120 TDIKVIGNGSFGVVYQARLAETRELVAIKKV-LQDKR-----FKNRELQIMRKLDHCNIV 173
Query: 190 LIHEIIVS-----DKNTISMGFQYMENDLSGM---LMDKSIQFSDSNIKHLMKQLFVGLQ 241
+ S D+ +++ +Y+ + + + +K M QLF L
Sbjct: 174 RLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLA 233
Query: 242 YLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
Y+H Q + HRDIK NLL+D + LK+ DFG AK+L N + + + +YR PEL
Sbjct: 234 YIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLV---RGEPNVSYICSRYYRAPEL 290
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
+ GATDY +D W GC+L EL G IFPG + VDQ I+ ++G+PT EQ +M +
Sbjct: 291 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM-NP 349
Query: 361 PWWFMLVPQI-SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF--- 416
+ PQI + + VF S+ P +A+ L S LL Y +R + EA H +F
Sbjct: 350 NYTEFKFPQIKAHPWTKVF---KSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
Query: 417 ----TNEPKPQPL 425
T P +PL
Sbjct: 407 RCLGTQLPNNRPL 419
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 150 bits (380), Expect = 3e-36
Identities = 116/373 (31%), Positives = 181/373 (48%), Gaps = 36/373 (9%)
Query: 75 GPETSGSRFEGHGSIPRGPRAMGSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQ 134
G +SG G G G G+S G R+ GK + + Q +A
Sbjct: 61 GASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDS-GKVTTVVATLGQGPERSQEVAY 119
Query: 135 -----VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNIS 189
+G G++G VY+A T +L+A+K++ L+ +R RE++++++L+H NI
Sbjct: 120 TDIKVIGNGSFGVVYQARLAETRELVAIKKV-LQDKR-----FKNRELQIMRKLDHCNIV 173
Query: 190 LIHEIIVS-----DKNTISMGFQYMENDLSGM---LMDKSIQFSDSNIKHLMKQLFVGLQ 241
+ S D+ +++ +Y+ + + + +K M QLF L
Sbjct: 174 RLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLA 233
Query: 242 YLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
Y+H Q + HRDIK NLL+D + LK+ DFG AK+L N + + + +YR PEL
Sbjct: 234 YIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLV---RGEPNVSYICSRYYRAPEL 290
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
+ GATDY +D W GC+L EL G IFPG + VDQ I+ ++G+PT EQ +M +
Sbjct: 291 IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM-NP 349
Query: 361 PWWFMLVPQI-SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF--- 416
+ PQI + + VF S+ P +A+ L S LL Y +R + EA H +F
Sbjct: 350 NYTEFKFPQIKAHPWTKVF---KSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDEL 406
Query: 417 ----TNEPKPQPL 425
T P +PL
Sbjct: 407 RCLGTQLPNNRPL 419
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 150 bits (379), Expect = 4e-36
Identities = 91/291 (31%), Positives = 153/291 (52%), Gaps = 10/291 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L VGEG+YG V K N TG+++A+K+ + ++REIKLL+QL H N+
Sbjct: 4 YENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENL 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+ K + F+++++ + L ++ + Q+ G+ + H I
Sbjct: 64 VNLLEVCKKKKRWYLV-FEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNI 122
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS-NTNRVITLWYRPPELLLGATDY 307
+HRDIK N+L+ G +K+ DFG A+ L ++P T+ V T WYR PELL+G Y
Sbjct: 123 IHRDIKPENILVSQSGVVKLCDFGFARTL---AAPGEVYTDYVATRWYRAPELLVGDVKY 179
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF--M 365
VD W GCL+ E+F G +FPG +++DQ I+ +G+ + + ++ + F +
Sbjct: 180 GKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGN-LIPRHQELFNKNPVFAGV 238
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+P+I + + + K+ + +DLA K L D D R E L H +F
Sbjct: 239 RLPEIKE--REPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 150 bits (379), Expect = 4e-36
Identities = 89/287 (31%), Positives = 151/287 (52%), Gaps = 12/287 (4%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQ--ERDGFPITSIREIKLLQQLNH 185
+++ + ++ G++G VY+ ++ ALKR+ + +GF I IRE+ +L+ + H
Sbjct: 25 NYEKVCRISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMILKHIRH 84
Query: 186 PNISLIHEIIVS-DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
NI I E++ + N + + + DL ++ + + L Q+ GL++LH
Sbjct: 85 RNIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVG-KIGMKAARFLTCQMLKGLKFLH 143
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGA 304
IVHRD+K SN+L+ G L+I DFGLA+ + + TN V+TLWYRP E+LLG+
Sbjct: 144 GAGIVHRDLKPSNILLMRDGGLRIADFGLARAIE-----SQMTNLVVTLWYRPIEILLGS 198
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
Y +D W GC++ E+ G I G E+DQ RI ++G PT + + LD+P +
Sbjct: 199 ETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADF-EGLDLPHFK 257
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEAL 411
+ + T++ F +F ++A LL +D R T ++ L
Sbjct: 258 NI--RRPSTFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQGL 302
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 150 bits (379), Expect = 4e-36
Identities = 94/324 (29%), Positives = 160/324 (49%), Gaps = 36/324 (11%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
+ F ++G+G YG V+KA + + + +ALK++ + RE+ LQ+
Sbjct: 9 IHEKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFG 68
Query: 185 -HPNISLIHEIIVSDKNT-ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQY 242
HPN+ ++ I +D + I + F++ME DL ++ SI D + +++M QLF +++
Sbjct: 69 KHPNVIKLYNIFRADNDRDIYLAFEFMEADLHNVIKKGSI-LKDVHKQYIMCQLFRAIRF 127
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN------TNRVITLWYR 296
LH ++HRD+K SN+L+D +K+ DFGLA+ L+ + T V T WYR
Sbjct: 128 LHSGNVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYR 187
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PE+LL A Y VD W GC+L E+ G A+FPGS+ ++Q +RI++ + P+
Sbjct: 188 SPEILLAAKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRAD--- 244
Query: 357 MLDMPWWFMLVPQISKTYKNVFFDEFSKVPQD------------ALDLASKLLRYDQDTR 404
+ I Y ++ + P+ A+D+ +LL + R
Sbjct: 245 ----------IASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAIDMVQRLLIFAPQKR 294
Query: 405 FTTTEALQHHYFT--NEPKPQPLL 426
T + L H Y + P +P+L
Sbjct: 295 LTVEQCLVHPYVVQFHNPSEEPVL 318
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 150 bits (378), Expect = 5e-36
Identities = 95/314 (30%), Positives = 161/314 (51%), Gaps = 24/314 (7%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN-HP 186
+++ + ++GEGT+ +V K +++ G A K+++ E + ++REI+ L++LN HP
Sbjct: 3 NYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIE-QVNNLREIQALRRLNPHP 61
Query: 187 NISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
NI ++HE++ K+ ++++ + M+ ++ ++ + S+ I H M QL L ++H+
Sbjct: 62 NILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHR 121
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I HRD+K N+LI + LK+ DFG + V S T + T WYR PE LL
Sbjct: 122 NGIFHRDVKPENILI-KQDVLKLGDFGSCRS---VYSKQPYTEYISTRWYRAPECLLTDG 177
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM-------L 358
Y Y++D W GC+ E+ + +FPG NE+DQ +I ++G+P + K
Sbjct: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNF 237
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
D P+ K + + PQ L L ++ YD D R +ALQH YF
Sbjct: 238 DFPF---------KKGSGIPLLTTNLSPQ-CLSLLHAMVAYDPDERIAAHQALQHPYFQE 287
Query: 419 EPKPQPLLLGPEFK 432
+ K + LG K
Sbjct: 288 QRKTEKRALGSHRK 301
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 149 bits (377), Expect = 6e-36
Identities = 87/290 (30%), Positives = 144/290 (49%), Gaps = 4/290 (1%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ + ++GEG+YG V+K N TG+++A+K+ ++ ++REI++L+QL HPN+
Sbjct: 5 YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNL 64
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+ K + + F+Y ++ + L + +K + Q + + H+
Sbjct: 65 VNLLEVF-RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 123
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRD+K N+LI +K+ DFG A+ LT S T+ V T WYR PELL+G T Y
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSD--YYTDYVATRWYRSPELLVGDTQYG 181
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVP 368
VD W GC+ EL +G ++PG ++VDQ I +G + + ++ +F V
Sbjct: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGD-LIPRHQQVFSTNQYFSGVK 240
Query: 369 QISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+F + AL L L D R T + L H YF N
Sbjct: 241 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFEN 290
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 149 bits (377), Expect = 6e-36
Identities = 90/290 (31%), Positives = 150/290 (51%), Gaps = 19/290 (6%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN---HPNI--- 188
+G+G YG VY+ ++H GK ALK++ + + +G P + +REI +++ L HPNI
Sbjct: 108 LGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISL 167
Query: 189 -SLIHEII-VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
S+ H++ V I+M + + DL L + + KH+ Q+ L +LH
Sbjct: 168 KSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTH 227
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
I+HRD+K N+L++ +K+ DFGL+K + S+ + T V+TLWYR PE+LL +
Sbjct: 228 SIIHRDLKPQNILLNRDQTVKLADFGLSK---EYSNTTAFTTLVVTLWYRSPEVLL-QSY 283
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y VD W GC++ E++ +F G NE +Q I MG+P + WP ++
Sbjct: 284 YNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSE------SVI 337
Query: 367 VPQISKTYKNVFFDEFS-KVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
Y+ + S ++ + A++ + LRYD R + AL H +
Sbjct: 338 ARDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPF 387
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 149 bits (376), Expect = 8e-36
Identities = 87/296 (29%), Positives = 155/296 (51%), Gaps = 8/296 (2%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ + + P+ +G G YG V + N T + +A+K++ E + ++RE+KLL+ L
Sbjct: 27 EIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLLRHL 86
Query: 184 NHPNISLIHEIIVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
H N+ + ++++ + + ++ M+ DL ++ + S+ + ++ + QL G
Sbjct: 87 RHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQIIKSSQV-LSNDHCQYFLFQLLRG 145
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
L+Y+H I+HRD+K NLL++ +LKI DFGLA+ + T V+T WYR PE
Sbjct: 146 LKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASN--TKGQFMTEYVVTRWYRAPE 203
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
LLL +Y +D W GC+ EL IF G+ ++Q + I++I+GS E+ + +D
Sbjct: 204 LLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQR-EEDLEFID 262
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
P + + + + A+DL K+L +D R + +EALQH Y
Sbjct: 263 NPKAKRYIRSLPYSPGMSLSRLYPGAHVLAIDLLQKMLVFDPSKRISVSEALQHPY 318
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 149 bits (376), Expect = 8e-36
Identities = 95/293 (32%), Positives = 152/293 (51%), Gaps = 12/293 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L+++GEG+YG VYK + TG L+A+KR ++ ++REI+LL+ L HPN+
Sbjct: 4 YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNL 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+ K + + F++ E + L + K + Q +G+ Y H+Q
Sbjct: 64 VSLLEVF-RRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGC 122
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN-TNRVITLWYRPPELLLGATDY 307
+HRDIK N+L+ +G +K+ DFG A+ L SP N T+ V T WYR PELL+G T Y
Sbjct: 123 LHRDIKPENILLTAQGQVKLCDFGFARML----SPGENYTDYVATRWYRAPELLVGDTQY 178
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF--- 364
VD W GCL EL G A++PG ++VDQ I +G L + ++ +F
Sbjct: 179 GTPVDVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGD-LLPRHIQIFGQNEYFKGI 237
Query: 365 -MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ VP + ++ + + P +D K L D R++ + +H YF
Sbjct: 238 TLPVPPTLEPLEDKMPAKSQQNPL-TIDFLKKCLDKDPTKRWSCEKLTKHSYF 289
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 149 bits (375), Expect = 1e-35
Identities = 86/307 (28%), Positives = 153/307 (49%), Gaps = 16/307 (5%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
++ ++Q L VG+G YG+V KA T +A+K+L + + RE++LL+ +
Sbjct: 19 EIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHM 78
Query: 184 NHPNISLIHEII--------VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQ 235
+H N+ + ++ + + M M+ DL+ ++ + + SD +++ L+ Q
Sbjct: 79 DHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKL--SDDHVQFLVYQ 136
Query: 236 LFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWY 295
+ GL+Y+H ++HRD+K SN+ ++ L+I DFGLA+ + + T V T WY
Sbjct: 137 ILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP-----AESEMTGYVATRWY 191
Query: 296 RPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWP 355
R PE++L Y D W GC++ EL G +FPG++ + Q I+ ++G+P +++
Sbjct: 192 RAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPA-DEFM 250
Query: 356 KMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+ + + + F D F A+DL K+L D D R T +AL H Y
Sbjct: 251 SRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPY 310
Query: 416 FTNEPKP 422
P
Sbjct: 311 MEKYHDP 317
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 147 bits (371), Expect = 3e-35
Identities = 94/295 (31%), Positives = 149/295 (49%), Gaps = 14/295 (4%)
Query: 130 QPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNIS 189
QP +G G +G V+ + +GK +ALK++ + REIK+L H N+
Sbjct: 44 QPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVL 103
Query: 190 LIHEIIVSDKNTISMGF----QYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
+ +I+ + + M++DL +++ D ++K + Q+ GL+YLH
Sbjct: 104 SLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPD-HVKVFVYQILRGLKYLHT 162
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I+HRDIK NLL+++ LKI DFGLA+ D + T+ V+T +YR PELL+GA
Sbjct: 163 ANILHRDIKPGNLLVNSNCILKICDFGLARTW-DQRDRLNMTHEVVTQYYRAPELLMGAR 221
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y VD W GC+ EL +F + ++Q Q I+ ++G+P+ E + +
Sbjct: 222 RYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHV 281
Query: 366 L-----VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
L P + YK D+ + +A+DL KLL +D D R + EALQH Y
Sbjct: 282 LRAGLRAPDTQRLYKIASPDDKN---HEAVDLLQKLLHFDPDKRISVEEALQHRY 333
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 147 bits (371), Expect = 3e-35
Identities = 94/295 (31%), Positives = 149/295 (49%), Gaps = 14/295 (4%)
Query: 130 QPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNIS 189
QP +G G +G V+ + +GK +ALK++ + REIK+L H N+
Sbjct: 69 QPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVL 128
Query: 190 LIHEIIVSDKNTISMGF----QYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
+ +I+ + + M++DL +++ D ++K + Q+ GL+YLH
Sbjct: 129 SLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPD-HVKVFVYQILRGLKYLHT 187
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I+HRDIK NLL+++ LKI DFGLA+ D + T+ V+T +YR PELL+GA
Sbjct: 188 ANILHRDIKPGNLLVNSNCILKICDFGLARTW-DQRDRLNMTHEVVTQYYRAPELLMGAR 246
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y VD W GC+ EL +F + ++Q Q I+ ++G+P+ E + +
Sbjct: 247 RYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHV 306
Query: 366 L-----VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
L P + YK D+ + +A+DL KLL +D D R + EALQH Y
Sbjct: 307 LRAGLRAPDTQRLYKIASPDDKN---HEAVDLLQKLLHFDPDKRISVEEALQHRY 358
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 147 bits (371), Expect = 3e-35
Identities = 94/295 (31%), Positives = 149/295 (49%), Gaps = 14/295 (4%)
Query: 130 QPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNIS 189
QP +G G +G V+ + +GK +ALK++ + REIK+L H N+
Sbjct: 241 QPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVL 300
Query: 190 LIHEIIVSDKNTISMGF----QYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
+ +I+ + + M++DL +++ D ++K + Q+ GL+YLH
Sbjct: 301 SLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPD-HVKVFVYQILRGLKYLHT 359
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I+HRDIK NLL+++ LKI DFGLA+ D + T+ V+T +YR PELL+GA
Sbjct: 360 ANILHRDIKPGNLLVNSNCILKICDFGLARTW-DQRDRLNMTHEVVTQYYRAPELLMGAR 418
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y VD W GC+ EL +F + ++Q Q I+ ++G+P+ E + +
Sbjct: 419 RYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHV 478
Query: 366 L-----VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
L P + YK D+ + +A+DL KLL +D D R + EALQH Y
Sbjct: 479 LRAGLRAPDTQRLYKIASPDDKN---HEAVDLLQKLLHFDPDKRISVEEALQHRY 530
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 146 bits (369), Expect = 5e-35
Identities = 99/301 (32%), Positives = 155/301 (50%), Gaps = 21/301 (6%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI-SLIHE 193
VG G++G V + + + A+KR+ L+ +R RE+++++ + HPNI LI
Sbjct: 38 VGSGSFGVVMQVHLIESDSKAAIKRV-LQDKR-----FKNRELQIMRIMKHPNIVDLIAY 91
Query: 194 IIVSDKNT----ISMGFQYMENDL---SGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
+ N+ +++ ++M + S + + + +K + QL L Y+H
Sbjct: 92 YYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHAS 151
Query: 247 QIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I HRDIK NLL+D G LK+ DFG AK L + N + + + +YR PEL+ GAT
Sbjct: 152 GICHRDIKPQNLLLDPENGILKLCDFGSAKILV---AGEPNVSYICSRYYRAPELIFGAT 208
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
DY + +D W GC++ EL G +FPG + +DQ I+ I+G+P+ EQ K ++ +
Sbjct: 209 DYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQ-IKTMNPNYMEH 267
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
PQI + F VP DALDL SK+L+Y R T EA+ H +F P
Sbjct: 268 RFPQIRPQPLSRVFSR--SVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELRDPNTK 325
Query: 426 L 426
L
Sbjct: 326 L 326
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 146 bits (368), Expect = 7e-35
Identities = 104/313 (33%), Positives = 161/313 (51%), Gaps = 21/313 (6%)
Query: 123 QDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
Q V+ S+ +G G++G V+ A+ T +++A+K++ L+ +R RE++++++
Sbjct: 30 QQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKV-LQDKR-----FKNRELQIMRK 83
Query: 183 LNHPNISLIHEIIVS-----DKNTISMGFQYMENDLSGMLMDKSIQFSDSN---IKHLMK 234
LNHPNI + S D+ +++ +Y+ + + S Q +K M
Sbjct: 84 LNHPNIVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMY 143
Query: 235 QLFVGLQYLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITL 293
QL L Y+H I HRDIK NLLID G LK+ DFG AK L + P N + + +
Sbjct: 144 QLLRSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVR-NEP--NVSYICSR 200
Query: 294 WYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQ 353
+YR PEL+ GAT+Y +D W G ++ EL G IFPG + VDQ I+ ++G+PT EQ
Sbjct: 201 YYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQ 260
Query: 354 WPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQH 413
M + + PQI N F + P +A+DL SK++ Y +R T A QH
Sbjct: 261 IQSM-NPNYKEFKFPQIKAHPWNKVFRVHT--PAEAIDLISKIIEYTPTSRPTPQAACQH 317
Query: 414 HYFTNEPKPQPLL 426
+F P L
Sbjct: 318 AFFDELRNPDARL 330
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 145 bits (367), Expect = 9e-35
Identities = 100/299 (33%), Positives = 157/299 (52%), Gaps = 23/299 (7%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S+ +G G++G VY+A+ +G+L+A+K++ L+ +R RE++++++L+H N
Sbjct: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV-LQDKR-----FKNRELQIMRKLDHCN 108
Query: 188 ISLIHEIIVS-----DKNTISMGFQYMENDLSGMLMDKSIQFSDSNI---KHLMKQLFVG 239
I + S D+ +++ Y+ + + S + K M QLF
Sbjct: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
Query: 240 LQYLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
L Y+H I HRDIK NLL+D + LK+ DFG AK+L N + + + +YR P
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLV---RGEPNVSYICSRYYRAP 225
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
EL+ GATDY +D W GC+L EL G IFPG + VDQ I+ ++G+PT EQ +M
Sbjct: 226 ELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM- 284
Query: 359 DMPWWFMLVPQI-SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ + PQI + + VF + P +A+ L S+LL Y R T EA H +F
Sbjct: 285 NPNYTEFKFPQIKAHPWTKVF---RPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 145 bits (367), Expect = 9e-35
Identities = 91/291 (31%), Positives = 151/291 (51%), Gaps = 12/291 (4%)
Query: 131 PLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISL 190
P+ +G G +E T + IA+K++ + ++REIKLL+ L H N+ +
Sbjct: 45 PIRPIGRGASVLSVDSE---THEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVV 101
Query: 191 IHEIIVSDKNT----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
I +II K + + F+ M+ DL ++ +D + ++ + Q+ GL+Y+H
Sbjct: 102 IKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRSNQ-SLNDDHCQYFLYQILRGLKYIHSA 160
Query: 247 QIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATD 306
++HRD+K SNLL+++ +LKITDFGLA+ ++ T V+T WYR PELLL +++
Sbjct: 161 NVLHRDLKPSNLLLNSNCDLKITDFGLARTTSETEYM---TEYVVTRWYRAPELLLNSSE 217
Query: 307 YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFML 366
Y +D W GC+ E+ +FPG + V Q + I ++GSP + L
Sbjct: 218 YTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSPDGASL-EFLRSANARKY 276
Query: 367 VPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
V ++ K + F F + A+DL K+L +D R T EAL + Y +
Sbjct: 277 VKELPKFPRQNFSARFPSMNSTAIDLLEKMLVFDPVKRITVEEALCYPYLS 327
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 144 bits (364), Expect = 2e-34
Identities = 97/329 (29%), Positives = 155/329 (46%), Gaps = 35/329 (10%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQ-ERDGFPITSIREIKLLQQLNHPN 187
F+ ++G GTYG VYKA K L+ E GF +++ REI L ++L HPN
Sbjct: 26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSACREIALFRELRHPN 85
Query: 188 ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKS--------IQFSDSNIKHLMKQLFVG 239
+ + + ++++ + + Y E+DL ++ I + +K+++ Q+ G
Sbjct: 86 LICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMVKNILFQILSG 145
Query: 240 LQYLHQQQIVHRDIKGSNLLI------DNRGNLKITDFGLAKKLTDVSSPASNTNRVI-T 292
+ YLH ++HRD+K +N+L+ D RG +KI D G ++ + P + + V+ T
Sbjct: 146 MHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVT 205
Query: 293 LWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNE---------VDQFQRIL 343
WYR PELLLGA Y +D W GC+ EL +F E DQ +RI
Sbjct: 206 FWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIF 265
Query: 344 SIMGSPTLEQWPKMLDMPWWFMLVPQIS------KTYKNV---FFDEFSKVPQDA-LDLA 393
++G P+ WP M MP L+ +T+ N +FD++ Q + L
Sbjct: 266 HLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFPNSLHRYFDKWKINSQSSPYRLL 325
Query: 394 SKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
KLL D R + EA+ YF +P
Sbjct: 326 VKLLTVDPTKRVSCEEAMNDIYFRKMERP 354
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 144 bits (362), Expect = 4e-34
Identities = 77/237 (32%), Positives = 127/237 (53%), Gaps = 8/237 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V +Q L+ VG G YG V A + TG +A+K+L + + RE++LL+ +
Sbjct: 19 EVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHM 78
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ---FSDSNIKHLMKQLFVGL 240
H N+ + ++ ++ Y+ L G ++ ++ +D +++ L+ Q+ GL
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+Y+H I+HRD+K SNL ++ LKI DFGLA+ D T V T WYR PE+
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDD-----EMTGYVATRWYRAPEI 193
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
+L Y VD W GC++ EL G +FPG++ +DQ + IL ++G+P E K+
Sbjct: 194 MLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 144 bits (362), Expect = 4e-34
Identities = 77/237 (32%), Positives = 127/237 (53%), Gaps = 8/237 (3%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
+V +Q L+ VG G YG V A + TG +A+K+L + + RE++LL+ +
Sbjct: 19 EVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHM 78
Query: 184 NHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ---FSDSNIKHLMKQLFVGL 240
H N+ + ++ ++ Y+ L G ++ ++ +D +++ L+ Q+ GL
Sbjct: 79 KHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 138
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+Y+H I+HRD+K SNL ++ LKI DFGLA+ D T V T WYR PE+
Sbjct: 139 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDD-----EMTGYVATRWYRAPEI 193
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
+L Y VD W GC++ EL G +FPG++ +DQ + IL ++G+P E K+
Sbjct: 194 MLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI 250
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 142 bits (357), Expect = 1e-33
Identities = 92/314 (29%), Positives = 158/314 (50%), Gaps = 16/314 (5%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGK--LIALKRLRLEQERDGFPITSIREIKLLQQ 182
V FQ + ++G G YG V A + +A+K++ + S+RE+KLL+
Sbjct: 19 VDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRH 78
Query: 183 LN-HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ----FSDSNIKHLMKQLF 237
H NI+ ++++ + S+ Y+ +L M + I+ +D++ + Q+
Sbjct: 79 FRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQIL 138
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN----TNRVITL 293
GL+Y+H ++HRD+K NLL++ LKI DFGLA+ ++ +P N T V T
Sbjct: 139 CGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSE--NPVENSQFLTEYVATR 196
Query: 294 WYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQ 353
WYR PE++L Y +D W GC+L E G IF G + V+Q +IL ++G+P ++
Sbjct: 197 WYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPP-DE 255
Query: 354 WPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQH 413
+ + + Q+ K F + + ALDL ++L +D R T EAL+H
Sbjct: 256 TLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEH 315
Query: 414 HYFT--NEPKPQPL 425
Y + ++P +P+
Sbjct: 316 PYLSIWHDPADEPV 329
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 142 bits (357), Expect = 1e-33
Identities = 88/294 (29%), Positives = 156/294 (52%), Gaps = 11/294 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L +VGEG+YG V K ++ +TG+++A+K + E+ ++REIK L+Q +H N+
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIK-IFYERPEQSVNKIAMREIKFLKQFHHENL 62
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+ K I + F+++++ + L ++ + Q+ + YLH I
Sbjct: 63 VNLIEVF-RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPAS-NTNRVITLWYRPPELLLGATDY 307
+HRDIK N+L+ G K+ DFG A+ L ++P T+ V T WYR PEL+L T Y
Sbjct: 122 IHRDIKPENILVSQSGITKLCDFGFARTL---AAPGDIYTDYVATRWYRAPELVLKDTSY 178
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMG--SPTLEQWPKMLDMPWWFM 365
VD W GC+++E+ G P S+++D +I+ +G SP L+ + + +
Sbjct: 179 GKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPI-FAGV 237
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNE 419
++PQ+ KN ++ K+ D+ L+ D R ++++ L H YFT +
Sbjct: 238 VLPQVQHP-KNA-RKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRD 289
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 141 bits (356), Expect = 2e-33
Identities = 81/290 (27%), Positives = 144/290 (48%), Gaps = 5/290 (1%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ L+++GEG+YG VYK +N TG+++A+K+ ++ ++REI++L+QL H N+
Sbjct: 4 YDRLSKLGEGSYGVVYKCKNRDTGQIVAIKKFVETEDDPHIKKIALREIRMLKQLKHQNL 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ E+ ++ + + F+ + + L +D IK ++ QL L++ H +
Sbjct: 64 VGLIEVFKRNRK-LHLVFELCDRTVLHELEKNPHGVNDELIKKIIYQLLEALKFCHSHKC 122
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRD+K N+ + +K+ DFG A+ +++ T+ V T WYR PELL+G Y
Sbjct: 123 IHRDVKPENIFLTRNDQVKLGDFGFARI---INTTEMYTDYVATRWYRSPELLVGDVQYG 179
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVP 368
VD W GC+ EL G A++PG +++DQ I +G L + + +F +
Sbjct: 180 PPVDIWAVGCVYAELLTGEALWPGRSDIDQLYHIRKTLGE-FLPRHISIFRTNQFFFGLS 238
Query: 369 QISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+ + LD K D RF+ +E + H F+N
Sbjct: 239 IPEPEHLEPLPSKLPNASSAQLDFLQKCFEMSPDRRFSCSELMLHGIFSN 288
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 141 bits (356), Expect = 2e-33
Identities = 97/299 (32%), Positives = 158/299 (52%), Gaps = 23/299 (7%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S+ +G G++G V++A+ TG+L+A+K++ ++ RE++++++L H N
Sbjct: 547 SYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKN------RELQIMRKLEHCN 600
Query: 188 ISLIHEIIVS-----DKNTISMGFQYMENDLSGMLMD--KSIQFSDSN-IKHLMKQLFVG 239
I + S D+ +++ +Y+ + + K+ Q N I+ M QLF
Sbjct: 601 IVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRS 660
Query: 240 LQYLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
L Y+H I HRDIK NLL+D LK+ DFG AK+L N + + + +YR P
Sbjct: 661 LAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEP---NVSYICSRYYRAP 717
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
EL+ GA +Y ++D W GC+L EL G IFPG + VDQ ++ ++G+PT EQ +M
Sbjct: 718 ELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREM- 776
Query: 359 DMPWWFMLVPQI-SKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ + PQI S ++ VF + P +A++L S LL Y R T +A H +F
Sbjct: 777 NPNYTEFKFPQIKSHPWQKVF---RIRTPTEAINLVSLLLEYTPSARITPLKACAHPFF 832
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 141 bits (355), Expect = 2e-33
Identities = 100/309 (32%), Positives = 157/309 (50%), Gaps = 30/309 (9%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S+ +G G++G VY+A+ +G+L+A+K++ L+ +R RE++++++L+H N
Sbjct: 55 SYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV-LQDKR-----FKNRELQIMRKLDHCN 108
Query: 188 ISLIHEIIVS-----DKNTISMGFQYMENDLSGMLMDKSIQFSDSNI---KHLMKQLFVG 239
I + S D+ +++ Y+ + + S + K M QLF
Sbjct: 109 IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRS 168
Query: 240 LQYLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
L Y+H I HRDIK NLL+D + LK+ DFG AK+L N + + + +YR P
Sbjct: 169 LAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLV---RGEPNVSYICSRYYRAP 225
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
EL+ GATDY +D W GC+L EL G IFPG + VDQ I+ ++G+PT EQ +M
Sbjct: 226 ELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREM- 284
Query: 359 DMPWWFMLVPQISK---TYKNVFFDEFS--------KVPQDALDLASKLLRYDQDTRFTT 407
+ + PQI T + F+ + P +A+ L S+LL Y R T
Sbjct: 285 NPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTP 344
Query: 408 TEALQHHYF 416
EA H +F
Sbjct: 345 LEACAHSFF 353
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 140 bits (353), Expect = 4e-33
Identities = 87/301 (28%), Positives = 155/301 (50%), Gaps = 9/301 (2%)
Query: 123 QDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
Q V+S F ++G+G YG V+KA + T +ALK++ + + RE+ L+
Sbjct: 19 QTVESIFDVRKRMGKGAYGIVWKATDRRTKNTVALKKVFDAFRDETDAQRTYREVIFLRA 78
Query: 183 LN-HPNISLIHEIIVSDKNT-ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGL 240
HPNI + +I + N + F++ME+DL ++ ++ D + + +M QL +
Sbjct: 79 FRCHPNIVRLVDIFKASNNLDFYLVFEFMESDLHNVIKRGNV-LKDVHKRFVMYQLINAI 137
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLT------DVSSPASNTNRVITLW 294
+++H ++HRD+K SN+LID++ LK+ DFGLA+ L+ D+ T+ V T W
Sbjct: 138 KFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRW 197
Query: 295 YRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQW 354
YR PE+L+ + +Y +D WG GC+L E+ +F G++ V+Q ++I++ + + T
Sbjct: 198 YRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDI 257
Query: 355 PKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHH 414
+ +L I + + + D + L LL + R T EA++H
Sbjct: 258 ASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHP 317
Query: 415 Y 415
Y
Sbjct: 318 Y 318
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 140 bits (352), Expect = 5e-33
Identities = 99/304 (32%), Positives = 149/304 (48%), Gaps = 16/304 (5%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
+G+G+YG V A + HTG+ +A+K++ E +REIKLL+ L HP+I I I
Sbjct: 31 IGKGSYGVVCSAYDTHTGEKVAIKKINDIFEHVSDATRILREIKLLRLLRHPDIVEIKHI 90
Query: 195 IVSDKNT----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVH 250
++ I + F+ ME+DL ++ + + + + QL GL+Y+H + H
Sbjct: 91 LLPPSRREFRDIYVVFELMESDLHQVIKAND-DLTPEHYQFFLYQLLRGLKYIHTANVFH 149
Query: 251 RDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLGATDYKY 309
RD+K N+L + LKI DFGLA+ D + T+ V T WYR PE L G+ KY
Sbjct: 150 RDLKPKNILANADCKLKICDFGLARVAFNDTPTAIFWTDYVATRWYRAPE-LCGSFFSKY 208
Query: 310 --EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC+ EL G +FPG N V Q + ++G+P+ E ++ + L
Sbjct: 209 TPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAIGRVRNEKARRYL- 267
Query: 368 PQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF------TNEPK 421
+ K F +F AL L K+L ++ R T EAL YF EP
Sbjct: 268 SSMRKKKPIPFSHKFPHTDPLALRLLEKMLSFEPKDRPTAEEALADVYFKGLAKVEREPS 327
Query: 422 PQPL 425
QP+
Sbjct: 328 AQPV 331
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 140 bits (352), Expect = 5e-33
Identities = 98/304 (32%), Positives = 151/304 (49%), Gaps = 16/304 (5%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG+G+YG V A + HTG+ +A+K++ E +REIKLL+ L HP++ I I
Sbjct: 110 VGKGSYGVVASAVDSHTGERVAIKKINDVFEHVSDATRILREIKLLRLLRHPDVVEIKHI 169
Query: 195 IV----SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVH 250
++ + I + F+ ME+DL ++ + + + + + QL GL+Y+H + H
Sbjct: 170 MLPPSRREFRDIYVVFELMESDLH-QVIKANDDLTPEHYQFFLYQLLRGLKYVHAANVFH 228
Query: 251 RDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLGATDYKY 309
RD+K N+L + LKI DFGLA+ D + T+ V T WYR PE L G+ KY
Sbjct: 229 RDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPE-LCGSFFSKY 287
Query: 310 --EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC+ E+ G +FPG N V Q + +G+P E ++ + L
Sbjct: 288 TPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESISRIRNEKARRYL- 346
Query: 368 PQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT------NEPK 421
+ K F +F K AL L +LL +D R + +AL YF+ EP
Sbjct: 347 SSMRKKQPVPFSHKFPKADPLALRLLERLLAFDPKDRASAEDALADPYFSGLSNSEREPT 406
Query: 422 PQPL 425
QP+
Sbjct: 407 TQPI 410
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 139 bits (351), Expect = 7e-33
Identities = 98/311 (31%), Positives = 153/311 (48%), Gaps = 14/311 (4%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
S +Q VG+G+YG V AE HTG +A+K++ E I +REIKLL+ L HP
Sbjct: 14 SQYQIQEVVGKGSYGVVASAECPHTGGKVAIKKMTNVFEHVSDAIRILREIKLLRLLRHP 73
Query: 187 NISLIHEIIV----SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQY 242
+I I I++ + I + F+ ME+DL +L + + + + QL GL++
Sbjct: 74 DIVEIKHIMLPPCRKEFKDIYVVFELMESDLHHVLKVND-DLTPQHHQFFLYQLLRGLKF 132
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELL 301
+H + HRD+K N+L + +KI D GLA+ TD S T+ V T WYR PEL
Sbjct: 133 MHSAHVFHRDLKPKNILANADCKIKICDLGLARVSFTDSPSAVFWTDYVATRWYRAPELC 192
Query: 302 LG-ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
++Y +D W GC+ E+ G +FPG N V Q + + ++G+P+ ++ +
Sbjct: 193 GSFYSNYTPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITLSRIRNE 252
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN-- 418
L + + F +F + AL L +L+ +D R + EAL YF
Sbjct: 253 KARKYL-GNMRRKDPVPFTHKFPNIDPVALKLLQRLIAFDPKDRPSAEEALADPYFQGLA 311
Query: 419 ----EPKPQPL 425
EP QP+
Sbjct: 312 NVDYEPSRQPI 322
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 139 bits (349), Expect = 1e-32
Identities = 101/352 (28%), Positives = 168/352 (47%), Gaps = 22/352 (6%)
Query: 100 AESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKV--YKAENVHTGKLIAL 157
A + G R IF K+ +++ + ++ + +G+G YG V K + IA+
Sbjct: 15 ASNLGAPQQRTIFAKERISIPGYYEI------IQFLGKGAYGTVCSVKFKGRSPAARIAV 68
Query: 158 KRLRLEQERDGFPITSIREIKLLQQLN-HPNI-SLIH-EIIVSDKNTISMGFQYMENDLS 214
K++ ++ +IRE+K + H NI +LI EI+ S +Q + +
Sbjct: 69 KKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDL 128
Query: 215 GMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLA 274
++ S+Q S+ +IK+ + Q+ GL+Y+H ++HRD+K N+L G LKI DFGLA
Sbjct: 129 AKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNGCLKICDFGLA 188
Query: 275 K-------KLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGA 327
+ K P TN V T WYR PELLL Y VD W GC+L E +A
Sbjct: 189 RGIHAGFFKCHSTVQPHI-TNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARK 247
Query: 328 AIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNV-FFDEFSKVP 386
+F G + + Q I+ ++G+P + K + W + + YK + + + F
Sbjct: 248 PVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFAS 307
Query: 387 QDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP--QPLLLGPEFKGSHE 436
+A++L LL +D R +A+ H + KP +P+ L F ++E
Sbjct: 308 HEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYE 359
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 139 bits (349), Expect = 1e-32
Identities = 92/301 (30%), Positives = 153/301 (50%), Gaps = 11/301 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ LA+ GEG+YG V+K N +G+++A+K+ ++ ++REI++L+QL HPN+
Sbjct: 4 YEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNL 63
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGML-MDKSIQFSDSNIKHLMK-----QLFVGLQY 242
+ E+ K + + F+Y ++ L L + + SDS + L +L
Sbjct: 64 VNLIEVF-RRKRKMHLVFEYCDHTLLNELERNPNGMDSDSIVGRLRSVADRSRLAPKNNQ 122
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
+ Q +HRDIK N+LI +G +KI DFG A+ L + T+ V T WYR PELL+
Sbjct: 123 IMILQCIHRDIKPENILITKQGIIKICDFGFAQILIPGDA---YTDYVATRWYRAPELLV 179
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G T Y VD W GC+ EL G ++PG ++VDQ I+ +G + + +
Sbjct: 180 GDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGK-LIPRHQSIFKSNG 238
Query: 363 WFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
+F + ++FS V AL+ L+ + D R T ++ L+ YF + +
Sbjct: 239 FFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEA 298
Query: 423 Q 423
Q
Sbjct: 299 Q 299
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 139 bits (349), Expect = 1e-32
Identities = 98/332 (29%), Positives = 169/332 (50%), Gaps = 25/332 (7%)
Query: 106 SHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQE 165
+ S I K L +D S++ +G G++G V++A+ + T + +A+K++ ++
Sbjct: 79 TESGRIITTKKKGLNDQKDKTISYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKR 138
Query: 166 RDGFPITSIREIKLLQQLNHPNISLIHEIIVS----DKNTISMGFQYMENDLSGMLMDKS 221
RE+++++ L+HPN+ + S D+ +++ +Y+ + +S
Sbjct: 139 YKN------RELQIMRMLDHPNVVELKHSFFSTTEKDELYLNLVLEYVPETI--YRASRS 190
Query: 222 IQFSDSNIKHLMKQLFV-----GLQYLHQQQ-IVHRDIKGSNLLIDN-RGNLKITDFGLA 274
+ ++ + QL+ + YLHQ + HRDIK NLL++N +KI DFG A
Sbjct: 191 YTKMNQHMPLIYIQLYTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFGSA 250
Query: 275 KKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSN 334
K L N + + + +YR PEL+ GAT+Y +D W GC++ ELF G +FPG
Sbjct: 251 KMLIPGEP---NISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLFPGET 307
Query: 335 EVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLAS 394
VDQ I+ I+G+P E+ K ++ + PQI + F +V +A+DLAS
Sbjct: 308 SVDQLVEIIKILGTPAREE-IKNMNPRYNDFKFPQIKAQPWHKIFRR--QVSPEAMDLAS 364
Query: 395 KLLRYDQDTRFTTTEALQHHYFTNEPKPQPLL 426
+LL+Y + R T EA H +F + P+ L
Sbjct: 365 RLLQYSPNLRCTALEACAHPFFDDLRDPRASL 396
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 139 bits (349), Expect = 1e-32
Identities = 90/295 (30%), Positives = 144/295 (48%), Gaps = 6/295 (2%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V QP +G G +G V+ + G+ +ALK+L + RE+K+L
Sbjct: 36 VPQDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFK 95
Query: 185 HPNISLIHEIIVSDK----NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGL 240
H N+ +I+ I + + +++DL +++ S +IK + Q+ GL
Sbjct: 96 HENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQ-HLSADHIKVFLYQILRGL 154
Query: 241 QYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPEL 300
+YLH +I+HRDIK NLL+++ LKI DFGLA+ + + T V+T +YR PE+
Sbjct: 155 KYLHSARILHRDIKPGNLLVNSNCVLKICDFGLAR-VEEPDQAKHMTQEVVTQYYRAPEI 213
Query: 301 LLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
L+GA Y VD W GC+ EL +F N V Q + I ++G+PT+E +
Sbjct: 214 LMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEG 273
Query: 361 PWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
ML +V + S +A+ L ++L +D D R + T+AL H Y
Sbjct: 274 ARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPY 328
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 138 bits (347), Expect = 2e-32
Identities = 93/295 (31%), Positives = 151/295 (50%), Gaps = 10/295 (3%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L +G+G+YG V A + HTG+ +A+K++ E + +RE+KLL+ L HP+I
Sbjct: 13 YRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHPDI 72
Query: 189 SLIHEIIV----SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
I I++ + I + F+ ME+DL ++ + + + + + Q+ L+++H
Sbjct: 73 VEIKSIMLPPSKREFKDIYVVFELMESDLH-QVIKANDDLTREHHQFFLYQMLRALKFMH 131
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLG 303
+ HRD+K N+L + LK+ DFGLA+ D + T+ V T WYR PE L G
Sbjct: 132 TANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPE-LCG 190
Query: 304 ATDYKY--EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
+ KY +D W GC+ E+ G +FPG + V Q + I ++G+P E + +
Sbjct: 191 SFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETISGVRNDK 250
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
L ++ K F +FSK AL L +LL +D R T EAL YF
Sbjct: 251 ARKYLT-EMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPYF 304
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 137 bits (346), Expect = 3e-32
Identities = 98/312 (31%), Positives = 155/312 (49%), Gaps = 16/312 (5%)
Query: 127 SSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHP 186
S +Q +G+G+YG V A + H+G+ +A+K++ E +REIKLL+ L HP
Sbjct: 124 SRYQIQEVIGKGSYGVVASAIDTHSGEKVAIKKINDVFEHVSDATRILREIKLLRLLRHP 183
Query: 187 NISLIHEIIV----SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQY 242
+I I +++ + I + F+ ME+DL ++ + + + + + QL GL++
Sbjct: 184 DIVEIKHVMLPPSRREFRDIYVVFELMESDLH-QVIKANDDLTPEHYQFFLYQLLRGLKF 242
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELL 301
+H + HRD+K N+L ++ LKI DFGLA+ D S T+ V T WYR PE L
Sbjct: 243 IHTANVFHRDLKPKNILANSDCKLKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPE-L 301
Query: 302 LGATDYKY--EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
G+ KY +D W GC+ E+ G +FPG N V Q + ++G+P E ++ +
Sbjct: 302 CGSFFSKYTPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEAIARIRN 361
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF--- 416
L + + F +F V AL L +LL +D R + EAL YF
Sbjct: 362 EKARRYL-GNMRRKPPVPFTHKFPHVDPLALRLLHRLLAFDPKDRPSAEEALADPYFYGL 420
Query: 417 ---TNEPKPQPL 425
EP QP+
Sbjct: 421 ANVDREPSTQPI 432
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 137 bits (345), Expect = 3e-32
Identities = 90/310 (29%), Positives = 161/310 (51%), Gaps = 29/310 (9%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G++G V++A+ + TG+ +A+K++ ++ RE++ ++ L+HPN+ +
Sbjct: 79 VGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN------RELQTMRLLDHPNVVSLKHC 132
Query: 195 IVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYL 243
S D+ +++ +Y+ + ++ ++ N +K Q+F L Y+
Sbjct: 133 FFSTTEKDELYLNLVLEYVPETVHRVIK----HYNKLNQRMPLVYVKLYTYQIFRSLSYI 188
Query: 244 HQQ-QIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
H+ + HRDIK NLL++ + +K+ DFG AK L N + + + +YR PEL+
Sbjct: 189 HRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLV---KGEPNISYICSRYYRAPELI 245
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
GAT+Y +D W GC+L EL G +FPG + VDQ I+ ++G+PT E+ K ++
Sbjct: 246 FGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE-IKCMNPN 304
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPK 421
+ PQI + F + ++P +A+DL S+LL+Y + R ++L H +F
Sbjct: 305 YTEFKFPQIKAHPWHKIFHK--RMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELRD 362
Query: 422 PQPLLLGPEF 431
P L F
Sbjct: 363 PNARLPNGRF 372
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 137 bits (345), Expect = 3e-32
Identities = 97/304 (31%), Positives = 148/304 (47%), Gaps = 16/304 (5%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG+G+YG V A + HTG+ +A+K++ + +REIKLL+ L HP++ I I
Sbjct: 96 VGKGSYGVVGSAIDTHTGERVAIKKINDVFDHISDATRILREIKLLRLLLHPDVVEIKHI 155
Query: 195 IVSDKNT----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVH 250
++ + + F+ ME+DL ++ + + + + QL GL+Y+H + H
Sbjct: 156 MLPPSRREFRDVYVVFELMESDLHQVIKAND-DLTPEHHQFFLYQLLRGLKYVHAANVFH 214
Query: 251 RDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLGATDYKY 309
RD+K N+L + LKI DFGLA+ D + T+ V T WYR PE L G+ KY
Sbjct: 215 RDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPE-LCGSFFSKY 273
Query: 310 --EVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC+ E+ G +FPG N V Q + +G+P E K+ + L
Sbjct: 274 TPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAISKIRNDKARRYL- 332
Query: 368 PQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF------TNEPK 421
+ K F +F K AL L +L+ +D R + EAL YF EP
Sbjct: 333 GNMRKKQPVPFSKKFPKADPSALRLLERLIAFDPKDRPSAEEALADPYFNGLSSKVREPS 392
Query: 422 PQPL 425
QP+
Sbjct: 393 TQPI 396
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 137 bits (344), Expect = 4e-32
Identities = 90/310 (29%), Positives = 160/310 (51%), Gaps = 29/310 (9%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G++G V++A+ + TG+ +A+K++ ++ RE++ ++ L+HPN+ +
Sbjct: 75 VGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKN------RELQTMRLLDHPNVVSLKHC 128
Query: 195 IVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYL 243
S D+ +++ +Y+ + ++ ++ N +K Q+F L Y+
Sbjct: 129 FFSTTEKDELYLNLVLEYVPETVHRVIK----HYNKLNQRMPLIYVKLYTYQIFRALSYI 184
Query: 244 HQQ-QIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
H+ + HRDIK NLL++ + +K+ DFG AK L N + + + +YR PEL+
Sbjct: 185 HRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLV---KGEPNISYICSRYYRAPELI 241
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
GAT+Y +D W GC+L EL G +FPG + VDQ I+ ++G+PT E+ K ++
Sbjct: 242 FGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE-IKCMNPN 300
Query: 362 WWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPK 421
+ PQI + F + ++P +A+DL S+LL+Y + R + L H +F
Sbjct: 301 YTEFKFPQIKAHPWHKIFHK--RMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFFDELRD 358
Query: 422 PQPLLLGPEF 431
P L F
Sbjct: 359 PNARLPNGRF 368
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 135 bits (340), Expect = 1e-31
Identities = 95/308 (30%), Positives = 152/308 (48%), Gaps = 22/308 (7%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + G +A+K+L + + RE+ LL+ +N
Sbjct: 22 VLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI--QFSDSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + I + + +L+ Q+ G+++
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART---ACTNFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ EL G IF G++ +DQ+ +++ +G+P+ E K+ P
Sbjct: 199 GM-GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKL--QPT 255
Query: 363 WFMLVPQISKTYKNVFFDEF-------SKVPQD------ALDLASKLLRYDQDTRFTTTE 409
V K Y + F+E S+ +D A DL SK+L D D R + E
Sbjct: 256 VRNYVENRPK-YPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 410 ALQHHYFT 417
AL+H Y T
Sbjct: 315 ALRHPYIT 322
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 135 bits (340), Expect = 1e-31
Identities = 95/308 (30%), Positives = 152/308 (48%), Gaps = 22/308 (7%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + G +A+K+L + + RE+ LL+ +N
Sbjct: 22 VLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI--QFSDSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + I + + +L+ Q+ G+++
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART---ACTNFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ EL G IF G++ +DQ+ +++ +G+P+ E K+ P
Sbjct: 199 GM-GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKL--QPT 255
Query: 363 WFMLVPQISKTYKNVFFDEF-------SKVPQD------ALDLASKLLRYDQDTRFTTTE 409
V K Y + F+E S+ +D A DL SK+L D D R + E
Sbjct: 256 VRNYVENRPK-YPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 410 ALQHHYFT 417
AL+H Y T
Sbjct: 315 ALRHPYIT 322
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 135 bits (340), Expect = 1e-31
Identities = 95/308 (30%), Positives = 152/308 (48%), Gaps = 22/308 (7%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + G +A+K+L + + RE+ LL+ +N
Sbjct: 22 VLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI--QFSDSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + I + + +L+ Q+ G+++
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART---ACTNFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ EL G IF G++ +DQ+ +++ +G+P+ E K+ P
Sbjct: 199 GM-GYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKL--QPT 255
Query: 363 WFMLVPQISKTYKNVFFDEF-------SKVPQD------ALDLASKLLRYDQDTRFTTTE 409
V K Y + F+E S+ +D A DL SK+L D D R + E
Sbjct: 256 VRNYVENRPK-YPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 410 ALQHHYFT 417
AL+H Y T
Sbjct: 315 ALRHPYIT 322
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 135 bits (340), Expect = 1e-31
Identities = 98/350 (28%), Positives = 154/350 (44%), Gaps = 57/350 (16%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ L +GEG YG V AE TG +A+K+ + + RE+KLL+ L H N+
Sbjct: 49 YNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNV 108
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMD---KSIQFSDSNIKHLMKQLFVGLQYL-- 243
+ ++ D + S+ Y + L G + K + +D I+ L+ Q+ GL+Y+
Sbjct: 109 LEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYMSH 168
Query: 244 ---------------------------HQQQIVHRDIKGSNLLIDNRGNLK--------- 267
H I+HRD+K SN+ ++ R +K
Sbjct: 169 QNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQLS 228
Query: 268 --------ITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCL 319
I DFGLA+ + A T V T WYR PE++L Y VD W GC+
Sbjct: 229 FLILSFFKILDFGLAR-----AQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCI 283
Query: 320 LVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFF 379
L EL +G +FPG + +DQ +I+S++G+P E W K + + S + F
Sbjct: 284 LAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSK-IQSEEARNYIKNRSPIIRQDFV 342
Query: 380 DEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPKPQPLLL 427
F AL+L +L D D R + + AL+H Y + P +P+ +
Sbjct: 343 TLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPVAM 392
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 135 bits (340), Expect = 1e-31
Identities = 90/301 (29%), Positives = 151/301 (49%), Gaps = 21/301 (6%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G++G V++A+ TG+++A+K++ ++ RE++++Q L+HPN+ +
Sbjct: 88 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDHPNVVCLKHS 141
Query: 195 IVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYLHQQ- 246
S + + + + + +S N +K Q+ GL YLH
Sbjct: 142 FYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICRGLAYLHNCC 201
Query: 247 QIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
+ HRDIK NLL++ + LKI DFG AK L N + + + +YR PEL+ GAT
Sbjct: 202 GLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV---KGEPNISYICSRYYRAPELIFGAT 258
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
+Y +D W GC++ EL G +FPG + VDQ I+ ++G+PT E+ K ++ +
Sbjct: 259 EYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE-IKCMNPNYTEF 317
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
PQI + F + ++P +A+DL + +Y + R T EA H +F P
Sbjct: 318 KFPQIKPHPWHKVFQK--RLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELRDPNAR 375
Query: 426 L 426
L
Sbjct: 376 L 376
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 135 bits (339), Expect = 2e-31
Identities = 90/294 (30%), Positives = 148/294 (49%), Gaps = 32/294 (10%)
Query: 156 ALKRLRLEQER------DGFPITSIREIKLLQQLNHPNISLIHEIIVSDKNTISMGFQYM 209
A+K+ + E++ G ++ RE+ L ++L++ +++ + EI + ++ + M ++Y
Sbjct: 181 AIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFL-ERKCVHMVYEYA 239
Query: 210 ENDLSGMLMDKSI----QFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGN 265
E+DL ++ S ++ +M QL G+ YLHQ ++HRD+K +N+++ G
Sbjct: 240 EHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGC 299
Query: 266 LKITDFGLAKKLTDVSSPASNTNRVI-TLWYRPPELLLGATDYKYEVDCWGCGCLLVELF 324
+KI D GLA+K ++ ++V+ T+WYR PELLLGA Y VD W GC+ EL
Sbjct: 300 VKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELI 359
Query: 325 AGAAIFPGSN-----------EVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKT 373
IF G +V+Q QRIL ++G+P + WP + P + QI+K
Sbjct: 360 GLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEY----DQITKF 415
Query: 374 YK-----NVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKP 422
K ++ + AL L LL YD R AL+H YFT P
Sbjct: 416 PKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIP 469
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 135 bits (339), Expect = 2e-31
Identities = 90/306 (29%), Positives = 161/306 (52%), Gaps = 25/306 (8%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S+ VG G++G V++A+ + TG+ +A+K++ ++ RE+++++ +HPN
Sbjct: 137 SYMAQRVVGTGSFGVVFQAKCLETGEQVAIKKVLQDKRYKN------RELQIMRLQDHPN 190
Query: 188 ISLIHEIIVS----DKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFV----- 238
+ + S D+ +++ +Y+ + K + ++ + QL+
Sbjct: 191 VVRLRHSFFSTTDKDELYLNLVLEYVPETV--YRASKHYTKMNQHMPIIFVQLYTYQICR 248
Query: 239 GLQYLHQQQ-IVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTNRVITLWYR 296
L YLH+ + HRDIK NLL++ + + LKI DFG AK L N + + + +YR
Sbjct: 249 ALNYLHRVVGVCHRDIKPQNLLVNPQTHQLKICDFGSAKMLVPGEP---NISYICSRYYR 305
Query: 297 PPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPK 356
PEL+ GAT+Y +D W GC++ EL G +FPG + +DQ I+ I+G+PT E+ +
Sbjct: 306 APELIFGATEYTNAIDMWSGGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREE-IR 364
Query: 357 MLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
++ + PQI + F + ++P +A+DL S+LL+Y + R T EA H +F
Sbjct: 365 CMNPNYTEFKFPQIKAHPWHKIFHK--RMPPEAVDLVSRLLQYSPNLRCTALEACAHPFF 422
Query: 417 TNEPKP 422
+ P
Sbjct: 423 DDLRDP 428
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 134 bits (338), Expect = 2e-31
Identities = 95/298 (31%), Positives = 151/298 (49%), Gaps = 21/298 (7%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S++P +G G++G V +A+ V T IA+KR+ ++ RE+++++ ++HPN
Sbjct: 24 SYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKN------RELQIMRAISHPN 77
Query: 188 I----SLIHEIIVS-DKNTISMGFQYMEN---DLSGMLMDKSIQFSDSNIKHLMKQLFVG 239
I + H S D+ + + +YM D + + +IK QLF
Sbjct: 78 IIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRA 137
Query: 240 LQYLHQQQIVHRDIKGSNLLIDNR-GNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
L YLH + HRDIK NLL+D + G LK+ DFG AK L S P N + + + +YR P
Sbjct: 138 LAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVP-SEP--NVSYICSRYYRAP 194
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
EL+ GAT Y ++D W C++ ELF G +FPG + V+Q I+ ++G+P+ + M
Sbjct: 195 ELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMN 254
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
L T ++V +K +A+DL K+L Y R + E L H +F
Sbjct: 255 PNYVNHSLPNVRPHTLESVMPHNCTK---NAMDLLHKMLTYVPSKRISAIEVLTHPFF 309
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 134 bits (337), Expect = 3e-31
Identities = 93/309 (30%), Positives = 156/309 (50%), Gaps = 26/309 (8%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
FQPL G G G V A + + +A+K++ L R ++REIK++++L+H NI
Sbjct: 23 FQPL---GFGVNGLVLSAVDSRACRKVAVKKIALSDARS--MKHALREIKIIRRLDHDNI 77
Query: 189 SLIHEIIVSDKNTISMGF-----------QYMENDLSGMLMDKSIQFSDSNIKHLMKQLF 237
++E++ K T G +YME DL+ +L ++ ++ + K M QL
Sbjct: 78 VKVYEVL-GPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGTL--AEEHAKLFMYQLL 134
Query: 238 VGLQYLHQQQIVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTD-VSSPASNTNRVITLWY 295
GL+Y+H ++HRD+K +N+ I LKI DFGLA+ + S + ++T WY
Sbjct: 135 RGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWY 194
Query: 296 RPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWP 355
R P LLL +Y +D W GC+L E+ G +F G++E++Q Q IL + E
Sbjct: 195 RSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKD 254
Query: 356 KMLD-MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHH 414
++L MP + ++ + + + +V +A+D K+L ++ R T LQH
Sbjct: 255 ELLRVMPSFVSSTWEVKRPLRKL----LPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHP 310
Query: 415 YFTNEPKPQ 423
Y + P+
Sbjct: 311 YMSPYSCPE 319
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 134 bits (337), Expect = 3e-31
Identities = 96/304 (31%), Positives = 148/304 (48%), Gaps = 16/304 (5%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
+G+G+YG V A + TG+ +A+K++ E +REIKLL+ L HP+I I I
Sbjct: 19 IGKGSYGVVCSAIDTLTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPDIVEIKHI 78
Query: 195 IVSDKNT----ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVH 250
++ I + F+ ME+DL ++ + + + + QL L+Y+H + H
Sbjct: 79 MLPPSRREFKDIYVVFELMESDLHQVIKAND-DLTREHYQFFLYQLLRALKYIHTANVYH 137
Query: 251 RDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLGATDYKY 309
RD+K N+L + LKI DFGLA+ D + T+ V T WYR PEL G+ KY
Sbjct: 138 RDLKPKNILANANCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYRAPELC-GSFYSKY 196
Query: 310 E--VDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+D W GC+ E+ G +FPG N V Q + ++G+P+L+ ++ + L
Sbjct: 197 TPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRNEKARRYLT 256
Query: 368 PQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF------TNEPK 421
+ K F +F +L L +LL +D R T EAL YF EP
Sbjct: 257 -SMRKKPPIPFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPYFKGLAKVEREPS 315
Query: 422 PQPL 425
QP+
Sbjct: 316 CQPI 319
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 134 bits (337), Expect = 3e-31
Identities = 90/331 (27%), Positives = 163/331 (49%), Gaps = 20/331 (6%)
Query: 103 AGDSHSRNIF-----GKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIAL 157
A D +S+N+F G K + F + + +G G +G V +A + K +A+
Sbjct: 13 APDYYSKNVFLEEQSGSKSCSNDLFCLEATQYLAQENLGAGAFGVVCRAIDSKLNKQVAI 72
Query: 158 KRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSDKNT---ISMGFQYMENDLS 214
K++ + ++REI++ ++L+H NI ++++ + + I + ME DL
Sbjct: 73 KKITRVFKNQSTAKCALREIRITRELSHENIINSTDVLMRESGSGQDIYIVMDLMETDLL 132
Query: 215 GMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLA 274
+L ++ + ++ Q+ GL+YLH I+HRD+K +NLL++ +LKI DFG++
Sbjct: 133 SVLKSNQT-LNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMS 191
Query: 275 K-----KLTDVSSPASN-----TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELF 324
+ K T +SP ++ + V TLWYR PE+LL +Y +VD W GC+L E+
Sbjct: 192 RSGPSTKTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEML 251
Query: 325 AGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSK 384
IF G++ Q Q ++ +G+P EQ + + P + F F
Sbjct: 252 LLRPIFTGTDSYSQIQLLIEYLGTPD-EQVIRRIKSPSIRDYISSFGPKTPLPFTAMFPN 310
Query: 385 VPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+A ++ SK+L+ RF+ + L+ +
Sbjct: 311 ASIEARNIVSKMLQISPWKRFSAEQLLEEPF 341
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 134 bits (336), Expect = 4e-31
Identities = 85/291 (29%), Positives = 140/291 (47%), Gaps = 12/291 (4%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG G YG V KA + K +A+K++ S+RE+++L++L H NI + ++
Sbjct: 63 VGAGAYGVVCKAMDTRNKKQVAIKKIPRAFTAHTLAKRSLREVRILRELLHENIIAVLDM 122
Query: 195 IVSDK---NTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHR 251
++ I + ME DL +L + + + ++ QL GL+YLH I+HR
Sbjct: 123 FTAEGAHGKDIYLVMDLMETDLHQILHSRQT-LMEQHFQYFFYQLLRGLKYLHSAGIIHR 181
Query: 252 DIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTN-------RVITLWYRPPELLLGA 304
D+K SNLL++ L+I DFG+A+ S+ + N V T WYR PE+L
Sbjct: 182 DLKPSNLLLNGDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRAPEILFSM 241
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
+Y +VD W GC+ E+ +FPG + V Q + I+ +GSP E+ +
Sbjct: 242 VEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPE-EEVINRITSDLVR 300
Query: 365 MLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
+ + F F K +A ++ S LL+ R++ + LQH +
Sbjct: 301 DSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQILQHPF 351
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 133 bits (335), Expect = 5e-31
Identities = 89/303 (29%), Positives = 150/303 (49%), Gaps = 16/303 (5%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 22 VLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K+ Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART---AGTSFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ G +FPG++ +DQ+ +++ +G+P E K+
Sbjct: 199 GM-GYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 363 WFM------LVPQISKTYKNVFF---DEFSKV-PQDALDLASKLLRYDQDTRFTTTEALQ 412
++ K + +V F E +K+ A DL SK+L D R + EALQ
Sbjct: 258 TYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQ 317
Query: 413 HHY 415
H Y
Sbjct: 318 HPY 320
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 133 bits (335), Expect = 5e-31
Identities = 89/303 (29%), Positives = 150/303 (49%), Gaps = 16/303 (5%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 22 VLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K+ Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLART---AGTSFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ G +FPG++ +DQ+ +++ +G+P E K+
Sbjct: 199 GM-GYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 363 WFM------LVPQISKTYKNVFF---DEFSKV-PQDALDLASKLLRYDQDTRFTTTEALQ 412
++ K + +V F E +K+ A DL SK+L D R + EALQ
Sbjct: 258 TYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQ 317
Query: 413 HHY 415
H Y
Sbjct: 318 HPY 320
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 133 bits (334), Expect = 6e-31
Identities = 97/319 (30%), Positives = 158/319 (49%), Gaps = 23/319 (7%)
Query: 108 SRNIFGKKPLALISFQD-VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQER 166
S+ ++ P I D V+ SF VG G++G V+ T + +A+K++ L+ +R
Sbjct: 17 SKQVYYAHPPPTIDPNDPVQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKV-LQDKR 75
Query: 167 DGFPITSIREIKLLQQLNHPNIS----LIHEIIVSDKNTISMGFQYMENDLSGML---MD 219
RE+++++ L+H NI +E D+ +++ +YM L L +
Sbjct: 76 -----FKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHFVH 130
Query: 220 KSIQFSDSNIKHLMKQLFVGLQYLHQ-QQIVHRDIKGSNLLID-NRGNLKITDFGLAKKL 277
+ S IK+ M QLF L YLH + HRDIK NLL+D +LK+ DFG AK+L
Sbjct: 131 QRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQL 190
Query: 278 TDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVD 337
N + + + +YR PEL+ GAT+Y ++D W GC++ EL G +FPG + +D
Sbjct: 191 KPTEP---NVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGID 247
Query: 338 QFQRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLL 397
Q I+ I+G+P+ ++ M + + PQI F K ++ + +L
Sbjct: 248 QLVEIIKILGTPSKQEICSM-NPNYMEHKFPQIKPI---PLSRVFKKEDDQTVEFLADVL 303
Query: 398 RYDQDTRFTTTEALQHHYF 416
+YD RF + L YF
Sbjct: 304 KYDPLERFNALQCLCSPYF 322
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 133 bits (334), Expect = 6e-31
Identities = 93/308 (30%), Positives = 151/308 (48%), Gaps = 22/308 (7%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + G +A+K+L + + RE+ LL+ +N
Sbjct: 22 VLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI--QFSDSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + I + + +L+ Q+ G+++
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TACTNFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P+ E K+ P
Sbjct: 199 G-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKL--QPT 255
Query: 363 WFMLVPQISKTYKNVFFDEF-------SKVPQD------ALDLASKLLRYDQDTRFTTTE 409
V K Y + F+E S+ +D A DL SK+L D D R + E
Sbjct: 256 VRNYVENRPK-YPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 410 ALQHHYFT 417
AL+H Y T
Sbjct: 315 ALRHPYIT 322
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 133 bits (334), Expect = 6e-31
Identities = 93/308 (30%), Positives = 151/308 (48%), Gaps = 22/308 (7%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + G +A+K+L + + RE+ LL+ +N
Sbjct: 22 VLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI--QFSDSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + I + + +L+ Q+ G+++
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TACTNFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P+ E K+ P
Sbjct: 199 G-MGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKL--QPT 255
Query: 363 WFMLVPQISKTYKNVFFDEF-------SKVPQD------ALDLASKLLRYDQDTRFTTTE 409
V K Y + F+E S+ +D A DL SK+L D D R + E
Sbjct: 256 VRNYVENRPK-YPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDE 314
Query: 410 ALQHHYFT 417
AL+H Y T
Sbjct: 315 ALRHPYIT 322
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 133 bits (334), Expect = 6e-31
Identities = 93/309 (30%), Positives = 150/309 (48%), Gaps = 14/309 (4%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ L +G+G+YG V A + TG+ +A+K++ E + +RE+KLL+ L HP+I
Sbjct: 13 YRILEVIGKGSYGVVCAAIDTQTGEKVAIKKINDVFEHVSDALRILREVKLLRLLRHPDI 72
Query: 189 SLIHEIIV----SDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
I I++ + I + F+ ME+DL ++ + + + + + Q+ L+Y+H
Sbjct: 73 VEIKSIMLPPSKREFKDIYVVFELMESDLH-QVIKANDDLTREHHQFFLYQMLRALKYMH 131
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAK-KLTDVSSPASNTNRVITLWYRPPELLLG 303
+ HRD+K N+L + LK+ DFGLA+ D + T+ V T WYR PEL
Sbjct: 132 TANVYHRDLKPKNILANANCKLKVCDFGLARVSFNDTPTTVFWTDYVATRWYRAPELCGS 191
Query: 304 -ATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
+ Y +D W GC+ E+ G +FPG + V Q I ++G+P E + +
Sbjct: 192 FCSKYTPAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETIAGVRNEKA 251
Query: 363 WFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF------ 416
L ++ K F +F AL L +LL +D R T EAL YF
Sbjct: 252 RKYL-NEMRKKNLVPFSQKFPNADPLALRLLQRLLAFDPKDRPTAAEALADPYFKCLAKV 310
Query: 417 TNEPKPQPL 425
EP QP+
Sbjct: 311 EREPSCQPI 319
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 132 bits (331), Expect = 1e-30
Identities = 95/307 (30%), Positives = 155/307 (49%), Gaps = 21/307 (6%)
Query: 123 QDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQ 182
++V+ F L +G G++G VYKA + IA+K+++++ D F RE+ ++ +
Sbjct: 31 REVEIQFTNLQLIGTGSFGAVYKAVLRENDEPIAIKKIKVD---DRF---KSRELTIMHE 84
Query: 183 LNHPNI-SLIHEIIVSDKNTISMGFQYMENDLSGM---LMDKSIQFSDSNIKHLMKQLFV 238
++HPNI L++ ++ +N ++ ++M DL+ + Q +IK M QL
Sbjct: 85 MDHPNIIRLLYYYVMQQENCLNFVMEFMPKDLAYVHRQFAHNDKQMPAYSIKLYMFQLLR 144
Query: 239 GLQYLHQQQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRP 297
G+ +LH IVHRDIK NLL+D + G LKI DFG AK+L + + P N + + +YR
Sbjct: 145 GIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFGSAKRL-EKNEP--NITYICSRYYRA 201
Query: 298 PELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM 357
PEL+ G+ +Y +D W G ++ EL + IF + VD + G+P+ E K
Sbjct: 202 PELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLADSAVDILALQIKAFGTPSKEDMAK- 260
Query: 358 LDMPWWFMLVPQISKTYKNVFFDEF--SKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
W + V T V +F K+ L+L + L++ D R EAL Y
Sbjct: 261 ----WNYEYVHIPYDTITGVGIQKFIGRKLSLSTLELLNSLMKMDPKLRIKPYEALTLPY 316
Query: 416 FTNEPKP 422
F + P
Sbjct: 317 FDDLRDP 323
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 132 bits (331), Expect = 1e-30
Identities = 89/301 (29%), Positives = 154/301 (50%), Gaps = 23/301 (7%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLIHEI 194
VG+G++G V++A+ + TG+ +A+K++ ++ RE++ ++ L+HPN+ +
Sbjct: 80 VGQGSFGIVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDHPNVVSLKHC 133
Query: 195 IVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSN-------IKHLMKQLFVGLQYLHQQQ 247
S + + + + S +S +N +K Q+ L Y+H
Sbjct: 134 FFSTTEKDELYLNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIHGGV 193
Query: 248 -IVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
+ HRDIK NLL++ + +K+ DFG AK L N + + + +YR PEL+ GAT
Sbjct: 194 GVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVLV---KGEPNISYICSRYYRAPELIFGAT 250
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
+Y +D W GC+L EL G +FPG + VDQ I+ ++G+PT E+ K ++ +
Sbjct: 251 EYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE-IKCMNPNYTEF 309
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPKPQPL 425
PQI + F + + P +A+DL S+LL+Y + R +T A+ H +F P
Sbjct: 310 KFPQIKAHPWHKIFHK--RTPPEAVDLVSRLLQYSPNLR--STAAIVHPFFDELRDPNTR 365
Query: 426 L 426
L
Sbjct: 366 L 366
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 131 bits (330), Expect = 2e-30
Identities = 92/324 (28%), Positives = 167/324 (51%), Gaps = 25/324 (7%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL 183
D+ S + L +G G G V+ A + K +A+K++ L + ++REIK++++L
Sbjct: 15 DLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQS--VKHALREIKIIRRL 72
Query: 184 NHPNISLIHEII-------------VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIK 230
+H NI + EI+ +++ N++ + +YME DL+ +L + + + +
Sbjct: 73 DHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLL--EEHAR 130
Query: 231 HLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTNR 289
M QL GL+Y+H ++HRD+K +NL I+ LKI DFGLA+ + S + +
Sbjct: 131 LFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSE 190
Query: 290 -VITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGS 348
++T WYR P LLL +Y +D W GC+ E+ G +F G++E++Q Q IL +
Sbjct: 191 GLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPV 250
Query: 349 PTLEQWPKMLD-MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTT 407
E ++L +P + + +++ +K + + ++ALD ++L + R T
Sbjct: 251 VHEEDRQELLSVIPVY--IRNDMTEPHKPL-TQLLPGISREALDFLEQILTFSPMDRLTA 307
Query: 408 TEALQHHYFT--NEPKPQPLLLGP 429
EAL H Y + + P +P+ P
Sbjct: 308 EEALSHPYMSIYSFPMDEPISSHP 331
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 131 bits (329), Expect = 2e-30
Identities = 99/306 (32%), Positives = 142/306 (46%), Gaps = 20/306 (6%)
Query: 135 VGEGTYGKVYKAENVHTGKL---IALKRLRLEQERDGFPITSIREIKLLQQLNHPNISLI 191
+G G++G V K V L +A+K++R RE KLLQ + H NI
Sbjct: 124 LGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICA 183
Query: 192 HEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ---------FSDSNIKHLMKQLFVGLQY 242
+I D+ Y+ + +G + + ++ +D +IK ++ Q+ L+Y
Sbjct: 184 LDIYTPDEEN-DFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKY 242
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
+H I+HRD+K NL + + +L I DFGLA+ L S T V T WYR PE++
Sbjct: 243 IHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLE--KKDTSLTQYVQTRWYRSPEVIY 300
Query: 303 GATD-YKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM-LDM 360
D Y D W GC+ EL G +FPG Q+QRI + GSP E K+ D
Sbjct: 301 WKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDN 360
Query: 361 PWWFMLVPQISKTYK-NVFFDEFS--KVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT 417
V Q T+K F D FS +D +DL KLL D + R T EA+QH Y
Sbjct: 361 SSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQHPYLA 420
Query: 418 NEPKPQ 423
P+
Sbjct: 421 EFSLPE 426
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 130 bits (328), Expect = 3e-30
Identities = 92/313 (29%), Positives = 158/313 (50%), Gaps = 40/313 (12%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN-ISLIHE 193
VG G++G V++A+ TG+++A+K++ ++ RE++++Q L+HPN ++L H
Sbjct: 89 VGTGSFGMVFQAKCRETGEVVAIKKVLQDKRYKN------RELQIMQMLDHPNAVALKHS 142
Query: 194 IIVSDKNT---ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFV---------GLQ 241
N +++ +++ ++ + S S LM ++V L
Sbjct: 143 FFSRTDNEEVYLNLVLEFVPETVN------RVARSYSRTNQLMPLIYVKLYTYQICRALA 196
Query: 242 YLHQQ-QIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPE 299
Y+H + HRDIK NLL++ + LKI DFG AK L N + + + +YR PE
Sbjct: 197 YIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLV---KGEPNVSYICSRYYRAPE 253
Query: 300 LLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLD 359
L+ GA++Y +D W GC++ EL G +FPG + VDQ I+ ++G+PT E+ K ++
Sbjct: 254 LIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREE-IKCMN 312
Query: 360 MPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF--- 416
+ PQI + F + ++P +A+DL + +Y + R T EA H F
Sbjct: 313 PNYTEFKFPQIKPHPWHKVFQK--RLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDEL 370
Query: 417 ----TNEPKPQPL 425
T P +PL
Sbjct: 371 RDPNTRLPNGRPL 383
>CE27220 [T] KOG0660 Mitogen-activated protein kinase
Length = 472
Score = 130 bits (326), Expect = 5e-30
Identities = 94/386 (24%), Positives = 166/386 (42%), Gaps = 39/386 (10%)
Query: 63 RNPRGKFNRPSNGPETSGSRFEGHGSIPRGPRAMGS-----SAESAGDSHSRNIFGKKPL 117
R+P+ ++ + + G PR P + S + + +R + G K
Sbjct: 8 RSPKAEYLNNFFNTNPTNGKSRGSQEAPRKPLGQTNLNVQGSMPAKKEGFNRVLDGLKKR 67
Query: 118 AL---ISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSI 174
L + +++P +G G +G V +A + + +A+K++ ++
Sbjct: 68 QLQHDFKLERAAETYEPTQNIGSGAFGIVCEAVETSSNQKVAIKKVAHASATPTLARRTL 127
Query: 175 REIKLLQQLNHPNISLIHEIIVSDKNT---ISMGFQYMENDLSGMLMDKSIQFSDSNIKH 231
REI++L+ +NHPNI + +I + + + M+N+L ++ + I
Sbjct: 128 REIRVLRYINHPNIVPLRDIFRTKGPLGIDVFLVMDLMQNNLHHIIYGNEDPLEEHYINA 187
Query: 232 LMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN----- 286
+ QL GL+YLH I HRD+K SNLL++ G L+I DFG+AK + S +
Sbjct: 188 FLGQLLRGLEYLHAACIAHRDLKPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCY 247
Query: 287 --TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILS 344
T V TL YR PELL ++ VD W GC+ E+ I PG + Q + +L+
Sbjct: 248 YMTQHVATLPYRAPELLFVLPEHSTAVDMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLT 307
Query: 345 IMGSPT---------------LEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDA 389
++G P ++ + + D W ++ + D+ + D
Sbjct: 308 MLGQPPQEVINEVRCDRTRKLIQDFGRKADAEWDDIMFCKARGD------DQIVRGNCDT 361
Query: 390 LDLASKLLRYDQDTRFTTTEALQHHY 415
+D +L +YD R +AL H Y
Sbjct: 362 IDFVKQLFQYDAQKRINIQDALLHPY 387
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 129 bits (325), Expect = 7e-30
Identities = 82/290 (28%), Positives = 143/290 (49%), Gaps = 6/290 (2%)
Query: 130 QPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNIS 189
+P +G G +G V+ + GK +ALK++ + RE+K+L H N+
Sbjct: 127 EPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVL 186
Query: 190 LIHEII----VSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQ 245
+I+ + I + + M++DL +++ SD ++K + Q+ GL+YLH
Sbjct: 187 SALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSD-HVKVFLYQILRGLKYLHS 245
Query: 246 QQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGAT 305
I+HRDIK NLL+++ LKI DFGLA+ + ++ T V+T +YR PE+L+G+
Sbjct: 246 AGILHRDIKPGNLLVNSNCVLKICDFGLAR-VEELDESRHMTQEVVTQYYRAPEILMGSR 304
Query: 306 DYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFM 365
Y +D W GC+ EL +F + + Q I ++G+P+LE + +
Sbjct: 305 HYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKAHI 364
Query: 366 LVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
L + V + S+ +A+ L ++L +D R + +AL H Y
Sbjct: 365 LRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAHPY 414
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 129 bits (324), Expect = 9e-30
Identities = 91/312 (29%), Positives = 145/312 (46%), Gaps = 34/312 (10%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+KL+ +N
Sbjct: 115 VLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVN 174
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI I K Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 175 HKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMDLDHERLSYLLYQMLCGIRH 234
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 235 LHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMM---TPYVVTRYYRAPEVIL 291
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC+ EL G +FPG + +DQ+ RI+ +G+P D +
Sbjct: 292 GM-GYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTP---------DRSF 341
Query: 363 WFMLVPQISKTYKN-----------VFFDEFSKVPQD--------ALDLASKLLRYDQDT 403
L P + +N +F D + D A DL S++L D +
Sbjct: 342 LERLQPTVRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPER 401
Query: 404 RFTTTEALQHHY 415
R + +AL+H Y
Sbjct: 402 RISVDDALRHPY 413
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 128 bits (321), Expect = 2e-29
Identities = 88/303 (29%), Positives = 148/303 (48%), Gaps = 16/303 (5%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 22 VLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K+ Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P E K+
Sbjct: 199 G-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 363 WFM------LVPQISKTYKNVFF---DEFSKV-PQDALDLASKLLRYDQDTRFTTTEALQ 412
++ K + +V F E +K+ A DL SK+L D R + EALQ
Sbjct: 258 TYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQ 317
Query: 413 HHY 415
H Y
Sbjct: 318 HPY 320
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 128 bits (321), Expect = 2e-29
Identities = 88/303 (29%), Positives = 148/303 (48%), Gaps = 16/303 (5%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 22 VLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K+ Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 82 HKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P E K+
Sbjct: 199 G-MGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVR 257
Query: 363 WFM------LVPQISKTYKNVFF---DEFSKV-PQDALDLASKLLRYDQDTRFTTTEALQ 412
++ K + +V F E +K+ A DL SK+L D R + EALQ
Sbjct: 258 TYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQ 317
Query: 413 HHY 415
H Y
Sbjct: 318 HPY 320
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 127 bits (320), Expect = 3e-29
Identities = 77/233 (33%), Positives = 112/233 (48%), Gaps = 22/233 (9%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
++ + G G +G V A + T K +A+KR+ + ++ REI L+ L+H NI
Sbjct: 8 YETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVSK---VSLAREISCLRNLHHRNI 64
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ + S DL SI + Q+ G+ YLH ++I
Sbjct: 65 LKLLDCFPSA-------------DLM------SIVTEEVPYTWYYTQILSGIAYLHSKEI 105
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRDIK N+L+ +R +KI DFG A V T WYR PELL G+ YK
Sbjct: 106 MHRDIKPENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLFGSKKYK 165
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMP 361
+VD W GC+L EL G IFPG +E++Q I ++G+P + WP MP
Sbjct: 166 PDVDIWAIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPNWRTMP 218
>Hs20502986 [T] KOG0660 Mitogen-activated protein kinase
Length = 277
Score = 127 bits (319), Expect = 3e-29
Identities = 81/242 (33%), Positives = 130/242 (53%), Gaps = 25/242 (10%)
Query: 134 QVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPIT-SIREIKLLQQL-NHPNI-SL 190
Q+G+G YG V+KA + TG+++A+K++ + RD + REI LLQ+ +HPNI SL
Sbjct: 18 QLGQGAYGIVWKAVDRRTGEVVAIKKI-FDAFRDKTDAQRTFREITLLQEFGDHPNIISL 76
Query: 191 IHEIIVSDKNTISMGFQYM-----------------ENDLSGMLMDKSIQFSDSNIKHLM 233
+ I + I + F++M + DL+ ++ + D +++ +
Sbjct: 77 LDVIRAENDRDIYLVFEFMGCPPSPPPPTAVRTLSADTDLNAVIRKGGL-LQDVHVRSIF 135
Query: 234 KQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN---TNRV 290
QL ++LH +VHRD K SN+L+D +K+ DFGLA+ L D+ + T V
Sbjct: 136 YQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYV 195
Query: 291 ITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPT 350
T WYR PE+LL + Y VD W GC+L E+ G +FPG++ + Q + IL + P+
Sbjct: 196 ATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPS 255
Query: 351 LE 352
E
Sbjct: 256 EE 257
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 127 bits (319), Expect = 3e-29
Identities = 88/324 (27%), Positives = 151/324 (46%), Gaps = 31/324 (9%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
+ S + L +G G G V A + T + +A+K+L + + RE KL++ +N
Sbjct: 20 IHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVN 79
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + +N Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 80 HKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIKH 139
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 140 LHSAGIIHRDLKPSNIVVKADCTLKILDFGLAR---TAGTTFMMTPYVVTRYYRAPEVIL 196
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPT------------ 350
G Y VD W GC++ E+ G +FPG++ +DQ+ +I+ +G+P+
Sbjct: 197 G-MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVR 255
Query: 351 --LEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTT 408
+E P+ + + + N + DA +L SK+L D + R +
Sbjct: 256 NYVENRPRYTGYSFDRLFPDGLFPNDNN---QNSRRKASDARNLLSKMLVIDPEQRISVD 312
Query: 409 EALQHHYF--------TNEPKPQP 424
EAL+H Y + P P+P
Sbjct: 313 EALKHEYINVWYDAEEVDAPAPEP 336
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 126 bits (316), Expect = 8e-29
Identities = 90/305 (29%), Positives = 148/305 (48%), Gaps = 20/305 (6%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 60 VLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 119
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 120 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 179
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 180 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TAGTSFMMTPYVVTRYYRAPEVIL 236
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P E K+ P
Sbjct: 237 G-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL--QPT 293
Query: 363 WFMLVPQISK----TYKNVFFD-------EFSKV-PQDALDLASKLLRYDQDTRFTTTEA 410
V K T+ +F D E +K+ A DL SK+L D R + +A
Sbjct: 294 VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDA 353
Query: 411 LQHHY 415
LQH Y
Sbjct: 354 LQHPY 358
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 126 bits (316), Expect = 8e-29
Identities = 90/305 (29%), Positives = 148/305 (48%), Gaps = 20/305 (6%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 60 VLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 119
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 120 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 179
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 180 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TAGTSFMMTPYVVTRYYRAPEVIL 236
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P E K+ P
Sbjct: 237 G-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL--QPT 293
Query: 363 WFMLVPQISK----TYKNVFFD-------EFSKV-PQDALDLASKLLRYDQDTRFTTTEA 410
V K T+ +F D E +K+ A DL SK+L D R + +A
Sbjct: 294 VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDA 353
Query: 411 LQHHY 415
LQH Y
Sbjct: 354 LQHPY 358
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 126 bits (316), Expect = 8e-29
Identities = 90/305 (29%), Positives = 148/305 (48%), Gaps = 20/305 (6%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
V +Q L +G G G V A + + +A+K+L + + RE+ L++ +N
Sbjct: 22 VLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN 81
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFS--DSNIKHLMKQLFVGLQY 242
H NI + + K Y+ +L + + IQ + +L+ Q+ G+++
Sbjct: 82 HKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKH 141
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLL 302
LH I+HRD+K SN+++ + LKI DFGLA+ + T V+T +YR PE++L
Sbjct: 142 LHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---TAGTSFMMTPYVVTRYYRAPEVIL 198
Query: 303 GATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPW 362
G YK VD W GC++ E+ +FPG + +DQ+ +++ +G+P E K+ P
Sbjct: 199 G-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL--QPT 255
Query: 363 WFMLVPQISK----TYKNVFFD-------EFSKV-PQDALDLASKLLRYDQDTRFTTTEA 410
V K T+ +F D E +K+ A DL SK+L D R + +A
Sbjct: 256 VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDA 315
Query: 411 LQHHY 415
LQH Y
Sbjct: 316 LQHPY 320
>At1g09000 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 666
Score = 125 bits (315), Expect = 1e-28
Identities = 81/293 (27%), Positives = 152/293 (51%), Gaps = 37/293 (12%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRL-----EQERDGFPITSIRE-IKLLQQLNHPNI 188
+G G +G VY N+ +G+L+A+K++ + +E+ I + E +KLL+ L+HPNI
Sbjct: 75 IGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNI 134
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ + V + +T+++ +++ L++K F +S ++ +QL +GL+YLH I
Sbjct: 135 -VRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAI 193
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRDIKG+N+L+DN+G +K+ DFG +K++ ++++ + T ++ PE++L T +
Sbjct: 194 MHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVIL-QTGHS 252
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVP 368
+ D W GC ++E+ G A P S Q++ + +I T + P + D
Sbjct: 253 FSADIWSVGCTVIEMVTGKA--PWS---QQYKEVAAIFFIGTTKSHPPIPD--------- 298
Query: 369 QISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTNEPK 421
+ DA D K L+ + R T +E L+H + + K
Sbjct: 299 ---------------TLSSDAKDFLLKCLQEVPNLRPTASELLKHPFVMGKHK 336
>Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 350
Score = 125 bits (314), Expect = 1e-28
Identities = 94/308 (30%), Positives = 153/308 (49%), Gaps = 22/308 (7%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNH 185
+ +Q + ++G G Y +V++A N+ + + +K L+ +++ RE+K+L+ L
Sbjct: 37 QDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKK-----IKREVKILENLRG 91
Query: 186 PN--ISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
I LI + T ++ F+Y+ N L +D +I+ M +L L Y
Sbjct: 92 GTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQI---LTDFDIRFYMYELLKALDYC 148
Query: 244 HQQQIVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELL 301
H + I+HRD+K N++ID++ L++ D+GLA + PA N RV + +++ PELL
Sbjct: 149 HSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA----EFYHPAQEYNVRVASRYFKGPELL 204
Query: 302 LGATDYKYEVDCWGCGCLLVEL-FAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM--- 357
+ Y Y +D W GC+L + F F G + DQ RI ++G+ L + K
Sbjct: 205 VDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHI 264
Query: 358 -LDMPWWFMLVPQISKTYKNVFFDEFSK-VPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
LD + +L K ++N E V +ALDL KLLRYD R T EA++H Y
Sbjct: 265 DLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPY 324
Query: 416 FTNEPKPQ 423
F K Q
Sbjct: 325 FYPVVKEQ 332
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 125 bits (314), Expect = 1e-28
Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 40/297 (13%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRL------EQERDGFPITSIREIKLLQQLNHPNI 188
+G G +G+VY N+ +G+L+A+K++ + +++ G E++LL+ L+HPNI
Sbjct: 74 IGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNI 133
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ + V + +++++ +++ L++K F + I KQL +GL+YLH I
Sbjct: 134 -VRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGI 192
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRDIKG+N+L+DN+G +++ DFG +KK+ ++++ + T ++ PE++L T +
Sbjct: 193 MHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVIL-QTGHS 251
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVP 368
+ D W GC ++E+ G P S + QF +L I + P+ L
Sbjct: 252 FSADIWSVGCTVIEMATGKP--PWSEQYQQFAAVLHIGRTKAHPPIPEDLS--------- 300
Query: 369 QISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT---NEPKP 422
+A D K L + R + TE LQH + T EP P
Sbjct: 301 ------------------PEAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQEPYP 339
>At1g54960 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 585
Score = 124 bits (312), Expect = 2e-28
Identities = 81/290 (27%), Positives = 150/290 (50%), Gaps = 37/290 (12%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRL-----EQERDGFPITSIRE-IKLLQQLNHPNI 188
+G G +G VY N+ +G+L+A+K++ + +E+ I + E +KLL+ L+HPNI
Sbjct: 74 IGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNI 133
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
+ D+ T+++ +++ L++K F +S ++ QL +GL+YLH I
Sbjct: 134 VRYLGTVREDE-TLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAI 192
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDYK 308
+HRDIKG+N+L+DN+G +K+ DFG +K++ ++++ + + T ++ PE++L T +
Sbjct: 193 MHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVIL-QTGHS 251
Query: 309 YEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLVP 368
+ D W GC ++E+ G A P S Q++ I +I T + P + D
Sbjct: 252 FSADIWSVGCTVIEMVTGKA--PWS---QQYKEIAAIFHIGTTKSHPPIPD--------- 297
Query: 369 QISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
+ DA D K L+ + + R T +E L+ + T+
Sbjct: 298 ---------------NISSDANDFLLKCLQQEPNLRPTASELLKVKWSTD 332
>At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 124 bits (310), Expect = 4e-28
Identities = 87/301 (28%), Positives = 160/301 (52%), Gaps = 22/301 (7%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL-N 184
+ ++ + +VG G Y +V++ +NV+T + +K L+ +++ REIK+LQ L
Sbjct: 31 QDDYEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKKK-----IKREIKILQNLCG 85
Query: 185 HPNISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
PNI +++I+ + + T S+ F+++ N + ++ ++ +D +I++ + +L L +
Sbjct: 86 GPNIVKLYDIVRDEHSKTPSLVFEFV-NSVDFKVLYPTL--TDYDIRYYIYELLKALDFC 142
Query: 244 HQQQIVHRDIKGSNLLIDNR-GNLKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELL 301
H Q I+HRD+K N++ID++ L++ D+GLA + P N RV + +++ PELL
Sbjct: 143 HSQGIMHRDVKPHNVMIDHQLRKLRLIDWGLA----EFYHPGKEYNVRVASRYFKGPELL 198
Query: 302 LGATDYKYEVDCWGCGCLLV-ELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKM--- 357
+ DY Y +D W GC+ +F F G + DQ +I ++G+ L+ +
Sbjct: 199 VDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTNELDHYLNKYQL 258
Query: 358 -LDMPWWFMLVPQISKTY-KNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
LD ++ + K + K + D V +A+D KLL+YD R T EA+ H Y
Sbjct: 259 DLDPQLEALVGRHVPKPWSKFINADNQHLVSPEAIDFLDKLLQYDHQDRLTAREAMDHPY 318
Query: 416 F 416
F
Sbjct: 319 F 319
>Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 240
Score = 123 bits (309), Expect = 5e-28
Identities = 90/302 (29%), Positives = 132/302 (42%), Gaps = 85/302 (28%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPNI 188
+ + ++GEGTYG VYK + TG+++A+K++RLE E +G P T+IREI LL++L
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR---- 59
Query: 189 SLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQI 248
H IVS L +LM S +L++ ++L
Sbjct: 60 ---HPNIVS---------------LQDVLMQDS-------------RLYLIFEFLSMD-- 86
Query: 249 VHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPA----SNTNRVITLWYRPPELLLGA 304
KK D P S+ +V+TLWYR PE+LLG+
Sbjct: 87 -------------------------LKKYLDSIPPGQYMDSSLVKVVTLWYRSPEVLLGS 121
Query: 305 TDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWF 364
Y VD W G + EL +F G +E+DQ RI +G+P E WP++ +
Sbjct: 122 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL---- 177
Query: 365 MLVPQISKTYKNVF--------FDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ YKN F + ++ LDL SK+L YD R + AL H YF
Sbjct: 178 -------QDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 230
Query: 417 TN 418
+
Sbjct: 231 ND 232
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 123 bits (308), Expect = 6e-28
Identities = 91/298 (30%), Positives = 139/298 (46%), Gaps = 22/298 (7%)
Query: 128 SFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
S+ VG G++G V + T + +A+K++ ++ RE++ ++ L HPN
Sbjct: 163 SYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKN------RELETMKMLCHPN 216
Query: 188 IS----LIHEIIVSDKNTISMGFQYMENDLSGML---MDKSIQFSDSNIKHLMKQLFVGL 240
+E D+ +++ YM L L ++ +Q IK QLF L
Sbjct: 217 TVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKAL 276
Query: 241 QYLHQ-QQIVHRDIKGSNLLID-NRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPP 298
YLH +I HRDIK NLL+D + KI DFG AK L N + + + +YR P
Sbjct: 277 NYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCL---KPDQPNVSYICSRYYRAP 333
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
EL+ GAT+Y +VD W C++ EL G +F G + +DQ I+ IMG PT ++ M
Sbjct: 334 ELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGM- 392
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
+ + + P I + F D LDL +K L+Y R + L YF
Sbjct: 393 NPNYEDHVFPNIKPI---TLAEIFKAEDPDTLDLLTKTLKYHPCERLVPLQCLLSSYF 447
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 122 bits (306), Expect = 1e-27
Identities = 72/237 (30%), Positives = 119/237 (49%), Gaps = 40/237 (16%)
Query: 209 MENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKI 268
ME+DL ++ S + ++++ + QL GL+Y+H Q++HRD+K SNLL++ LKI
Sbjct: 1 MESDLH-QIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKI 59
Query: 269 TDFGLAKKLTDVSSPASN----TNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELF 324
DFG+A+ L +SPA + T V T WYR PEL+L +Y +D W GC+ E+
Sbjct: 60 GDFGMARGLC--TSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 117
Query: 325 AGAAIFPGSNEVDQFQRILSIMGSPT---------------LEQWPKMLDMPWWFMLVPQ 369
A +FPG N V Q Q I+ ++G+P+ ++ P +PW +
Sbjct: 118 ARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETV---- 173
Query: 370 ISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFT--NEPKPQP 424
+ + AL L ++LR++ R + AL+H + ++P +P
Sbjct: 174 ------------YPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEP 218
>Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 391
Score = 121 bits (303), Expect = 2e-27
Identities = 90/308 (29%), Positives = 153/308 (49%), Gaps = 22/308 (7%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNH 185
+ +Q + ++G G Y +V++A N+ + + +K L+ +++ REIK+L+ L
Sbjct: 36 QDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKK-----IKREIKILENLRG 90
Query: 186 -PNISLIHEIIVSD-KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
PNI + +I+ T ++ F+++ N L +D +I+ M ++ L Y
Sbjct: 91 GPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQT---LTDYDIRFYMYEILKALDYC 147
Query: 244 HQQQIVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELL 301
H I+HRD+K N++ID+ L++ D+GLA + P N RV + +++ PELL
Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA----EFYHPGQEYNVRVASRYFKGPELL 203
Query: 302 LGATDYKYEVDCWGCGCLLVEL-FAGAAIFPGSNEVDQFQRILSIMGSPTL----EQWPK 356
+ Y Y +D W GC+L + F F G + DQ RI ++G+ L +++
Sbjct: 204 VDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNI 263
Query: 357 MLDMPWWFMLVPQISKTYKNVFFDEFSK-VPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
LD + +L K ++ E V +ALD KLLRYD +R T EA++H Y
Sbjct: 264 ELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPY 323
Query: 416 FTNEPKPQ 423
F K Q
Sbjct: 324 FYTVVKDQ 331
>YJL095w [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1478
Score = 119 bits (298), Expect = 9e-27
Identities = 70/199 (35%), Positives = 115/199 (57%), Gaps = 10/199 (5%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRL-----EQERDGFPITSIR-EIKLLQQLNHPNI 188
+G+G++G VY NV TG+++A+K++ + + E + ++R E+ L+ L+H NI
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNI 1240
Query: 189 SLIHEIIVSDKNTI-SMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQ 247
+ + +KN I S+ +Y+ G L+ +F + IKHL Q+ GL YLH +
Sbjct: 1241 --VQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKG 1298
Query: 248 IVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELLLGATDY 307
I+HRD+K NLL+D G KI+DFG+++K D+ S + T R W PE++ Y
Sbjct: 1299 ILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFW-MAPEMVDTKQGY 1357
Query: 308 KYEVDCWGCGCLLVELFAG 326
+VD W GC+++E+FAG
Sbjct: 1358 SAKVDIWSLGCIVLEMFAG 1376
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 119 bits (297), Expect = 1e-26
Identities = 82/251 (32%), Positives = 127/251 (49%), Gaps = 15/251 (5%)
Query: 175 REIKLLQQLNHPNI----SLIHEIIVS-DKNTISMGFQYMEN---DLSGMLMDKSIQFSD 226
RE+++++ ++HPNI + H S D+ + + +YM D + +
Sbjct: 34 RELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPN 93
Query: 227 SNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNR-GNLKITDFGLAKKLTDVSSPAS 285
+IK QLF L YLH + HRDIK NLL+D + G LK+ DFG AK L S P
Sbjct: 94 LSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVP-SEP-- 150
Query: 286 NTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSI 345
N + + + +YR PEL+ GAT Y ++D W C++ ELF G +FPG + V+Q I+ +
Sbjct: 151 NVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRV 210
Query: 346 MGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRF 405
+G+P+ + M L T ++V +K +A+DL K+L Y R
Sbjct: 211 LGTPSYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTK---NAMDLLHKMLTYVPSKRI 267
Query: 406 TTTEALQHHYF 416
+ E L H +F
Sbjct: 268 SAIEVLTHPFF 278
>At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 119 bits (297), Expect = 1e-26
Identities = 88/301 (29%), Positives = 152/301 (50%), Gaps = 22/301 (7%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL-N 184
+ ++ + +VG G Y +V++ NV++ + +K L+ +++ REIK+LQ L
Sbjct: 31 QDDYEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKKKK-----IRREIKILQNLCG 85
Query: 185 HPNISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
PNI + +++ + T S+ F+Y+ + +L +D +I++ + +L L +
Sbjct: 86 GPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPT---LTDYDIRYYIYELLKALDFC 142
Query: 244 HQQQIVHRDIKGSNLLIDNR-GNLKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELL 301
H Q I+HRD+K N++ID+ L++ D+GLA + P N RV + +++ PELL
Sbjct: 143 HSQGIMHRDVKPHNVMIDHELRKLRLIDWGLA----EFYHPGKEYNVRVASRYFKGPELL 198
Query: 302 LGATDYKYEVDCWGCGCLLVEL-FAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
+ DY Y +D W GC+ + F F G + DQ +I ++G+ L + +
Sbjct: 199 VDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQL 258
Query: 361 ---PWWFMLVPQISKTYKNVFF--DEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
P LV + S+ + F D V +A+D KLLRYD R T EA+ H Y
Sbjct: 259 ELDPQLEALVGRHSRKPWSKFINADNQHLVSPEAIDFLDKLLRYDHQDRLTAKEAMAHAY 318
Query: 416 F 416
F
Sbjct: 319 F 319
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 118 bits (296), Expect = 2e-26
Identities = 85/297 (28%), Positives = 151/297 (50%), Gaps = 51/297 (17%)
Query: 133 AQVGEGTYGKVYKAENVHTGKLIALKRLRLE-----QERDGFPITSIR-EIKLLQQLNHP 186
A +G G++G+VY N +G+L+A+K++ L+ ++R + ++ EI LLQ+L+H
Sbjct: 101 ALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHE 160
Query: 187 NISLIHEIIVSDKNT--ISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLH 244
+I + + S+ N+ +++ +Y+ L+ F ++ +K+ +KQ GL+YLH
Sbjct: 161 HIV---QYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLH 217
Query: 245 QQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTN------RVITLWYRPP 298
+ IVHRDIKG+N+L+DN+G +KI+DFG++KKL +++S ++ T + + W P
Sbjct: 218 SRGIVHRDIKGANILVDNKGKIKISDFGISKKL-ELNSTSTKTGGARPSFQGSSFWMAPE 276
Query: 299 ELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKML 358
++ T + + D W GCL++E+ +P DQ Q I I G L ++P
Sbjct: 277 --VVKQTMHTEKTDIWSLGCLVIEMLTSKHPYP---NCDQMQAIFRI-GENILPEFP--- 327
Query: 359 DMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
S + A+D K D + R T +E L H +
Sbjct: 328 ------------------------SNISSSAIDFLEKTFAIDCNLRPTASELLSHPF 360
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 117 bits (293), Expect = 4e-26
Identities = 74/246 (30%), Positives = 134/246 (54%), Gaps = 15/246 (6%)
Query: 112 FGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGK-LIALKRLRLEQERDGFP 170
+ K+ IS +V + + +VG+GT+G VY A K ++A+K ++ + +
Sbjct: 22 YTKEVRKCISIDEV---YNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVS-D 77
Query: 171 ITSIREIKLLQQLN-HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMD-KSIQFSDSN 228
T +RE+ L +L+ + NI I ++ + + + ++++ +L ++ K+ +
Sbjct: 78 ATRLREVHSLLRLSENENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQ 137
Query: 229 IKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRG-----NLKITDFGLAKKLTDVSSP 283
++ +M+Q+F GL ++H HRD+K N+LI + N+KI DFGLA+ +++S
Sbjct: 138 VQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAR---EINSR 194
Query: 284 ASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRIL 343
T V T WYR PELLL + Y + VD + GC+ E+ IFPG+++ DQ ++
Sbjct: 195 PPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMC 254
Query: 344 SIMGSP 349
I+GSP
Sbjct: 255 EILGSP 260
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 116 bits (290), Expect = 8e-26
Identities = 77/307 (25%), Positives = 149/307 (48%), Gaps = 19/307 (6%)
Query: 125 VKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLN 184
+ + + L+ + G G V A+++ T + +A+K+++ + RE LL +
Sbjct: 34 IPTRYVNLSFLNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLTTIK 93
Query: 185 HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI---QFSDSNIKHLMKQLFVGLQ 241
HPNI + D + + Y+ +L + + I + + + Q ++
Sbjct: 94 HPNIIRLLNAFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDHKTLSFFVYQSLCAIK 153
Query: 242 YLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVITLWYRPPELL 301
+LH ++HRD+K SN+++++R LK+ DFGLA+K +V + ++ V+T +YR PE++
Sbjct: 154 HLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLARK-KNVDTSMRMSDYVVTRYYRAPEVI 212
Query: 302 LGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPT---LEQWPKML 358
LG Y +VD W GC+ E+ +FPG + +DQ+ +I S++G+P + Q +
Sbjct: 213 LG-LPYSEKVDIWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSA 271
Query: 359 DMPWWFMLVPQISKTYKNVFFD----------EFSKVPQDALDLASKLLRYDQDTRFTTT 408
M + L ++ + + D P A DL +L+ + + R++
Sbjct: 272 AM-YVRSLPRHQARAFSEIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVE 330
Query: 409 EALQHHY 415
+AL H Y
Sbjct: 331 DALNHPY 337
>At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 333
Score = 115 bits (289), Expect = 1e-25
Identities = 84/301 (27%), Positives = 148/301 (48%), Gaps = 22/301 (7%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQL-N 184
+ ++ + +VG G Y +V++ N++ + +K L+ +++ REIK+LQ L
Sbjct: 31 QDDYEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKKK-----IRREIKILQNLCG 85
Query: 185 HPNISLIHEIIVSDKN-TISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
PNI + +++ + T S+ F+Y+ + +L +D +I++ + +L L +
Sbjct: 86 GPNIVKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPT---LTDYDIRYYIYELLKALDFC 142
Query: 244 HQQQIVHRDIKGSNLLIDNR-GNLKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELL 301
H Q I+HRD+K N++ID+ L++ D+GLA + P N RV + +++ PELL
Sbjct: 143 HSQGIMHRDVKPHNVMIDHELRKLRLIDWGLA----EFYHPGKEYNVRVASRYFKGPELL 198
Query: 302 LGATDYKYEVDCWGCGCLLV-ELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDM 360
+ DY Y +D W GC+ +F F G + DQ +I ++G+ L + +
Sbjct: 199 VDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNQDQLVKIAKVLGTDELNAYLNKYQL 258
Query: 361 PWWFMLVPQISK-----TYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
L + + K + D V +A+D KLLRYD R T EA+ H Y
Sbjct: 259 ELDTQLEALVGRHSRKPWSKFINADNRHLVSPEAIDYLDKLLRYDHQDRLTAKEAMAHPY 318
Query: 416 F 416
F
Sbjct: 319 F 319
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 115 bits (289), Expect = 1e-25
Identities = 94/314 (29%), Positives = 149/314 (46%), Gaps = 46/314 (14%)
Query: 40 QPNRPNNHHNTAGNVNVNRSLGKRNPRGKFN---RPSNGPETSGSRFEGHGSIPRGPRAM 96
+P P H +G V++ S G RN G+ + P P TS P P A+
Sbjct: 148 RPTSPR-HQRLSGVVSLESSTG-RNDDGRSSSECHPLPRPPTS----------PTSPSAV 195
Query: 97 GSSAESAGDSHSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIA 156
S G S + F S+++ +G GT+G+VY N GK+ A
Sbjct: 196 HGSRIGGGYETSPSGF--------------STWKKGKFLGSGTFGQVYLGFNSEKGKMCA 241
Query: 157 LKRLRL---EQERDGFPITSIREIKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDL 213
+K +++ +Q +EI LL QL HPNI + +S++ T+S+ +Y+
Sbjct: 242 IKEVKVISDDQTSKECLKQLNQEINLLNQLCHPNIVQYYGSELSEE-TLSVYLEYVSGGS 300
Query: 214 SGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGL 273
L+ F++ I++ +Q+ GL YLH + VHRDIKG+N+L+D G +K+ DFG+
Sbjct: 301 IHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPNGEIKLADFGM 360
Query: 274 AKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVEL---------F 324
AK +T S+ S + ++ PE+++ Y + VD W GC ++E+ F
Sbjct: 361 AKHVTAFSTMLSFKG---SPYWMAPEVVMSQNGYTHAVDIWSLGCTILEMATSKPPWSQF 417
Query: 325 AG-AAIFPGSNEVD 337
G AAIF N D
Sbjct: 418 EGVAAIFKIGNSKD 431
>7289745 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 336
Score = 115 bits (288), Expect = 1e-25
Identities = 88/301 (29%), Positives = 147/301 (48%), Gaps = 22/301 (7%)
Query: 126 KSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIREIKLLQQLNH 185
+ +Q + ++G G Y +V++A N+ T + +K L+ +++ REIK+L+ L
Sbjct: 34 QDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKK-----IKREIKILENLRG 88
Query: 186 PNISLIHEIIVSD--KNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYL 243
+ +V D T ++ F+++ N L +D I++ + +L L Y
Sbjct: 89 GTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQT---LTDYEIRYYLFELLKALDYC 145
Query: 244 HQQQIVHRDIKGSNLLIDNRGN-LKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELL 301
H I+HRD+K N++ID+ L++ D+GLA + P N RV + +++ PELL
Sbjct: 146 HSMGIMHRDVKPHNVMIDHENRKLRLIDWGLA----EFYHPGQEYNVRVASRYFKGPELL 201
Query: 302 LGATDYKYEVDCWGCGCLLVEL-FAGAAIFPGSNEVDQFQRILSIMGSPTL----EQWPK 356
+ Y Y +D W GC+L + F F G + DQ RI ++G+ L +++
Sbjct: 202 VDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNI 261
Query: 357 MLDMPWWFMLVPQISKTYKN-VFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHY 415
LD + +L K ++ V D V +ALD KLLRYD R T EA+ H Y
Sbjct: 262 DLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPY 321
Query: 416 F 416
F
Sbjct: 322 F 322
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 115 bits (287), Expect = 2e-25
Identities = 79/266 (29%), Positives = 131/266 (48%), Gaps = 28/266 (10%)
Query: 124 DVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQERDGFPITSIR-EIKLLQQ 182
+++ ++ L +G+GTYGKV KA +G+L+A+K +R ++ +D + IR EI+++
Sbjct: 48 NLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSS 106
Query: 183 LNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQY 242
LNHP+I IHE+ + + + DL + ++ Q S+ +H +Q+ + Y
Sbjct: 107 LNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQ-QLSEREARHFFRQIVSAVHY 165
Query: 243 LHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKL-------TDVSSPASNTNRVITLWY 295
HQ ++VHRD+K N+L+D GN+KI DFGL+ T SP Y
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPL----------Y 215
Query: 296 RPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWP 355
PE++ G EVD W G LL L G F G + + ++ + + + P
Sbjct: 216 ASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDH----KILVKQISNGAYREPP 271
Query: 356 KMLD----MPWWFMLVPQISKTYKNV 377
K D + W M+ P T ++V
Sbjct: 272 KPSDACGLIRWLLMVNPTRRATLEDV 297
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 115 bits (287), Expect = 2e-25
Identities = 92/330 (27%), Positives = 147/330 (43%), Gaps = 55/330 (16%)
Query: 107 HSRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKLIALKRLRLEQER 166
HS N FG + + + +++ +G G++GKV AE+V TG +A+K L + +
Sbjct: 3 HSSNRFGNNGV-----ESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIK 57
Query: 167 DGFPITSIR-EIKLLQQLNHPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSIQ-- 223
+ +R EIK+L+ HP+I +E+I T S + ME SG L D ++
Sbjct: 58 NMEMEEKVRREIKILRLFMHPHIIRQYEVI----ETTSDIYVVMEYVKSGELFDYIVEKG 113
Query: 224 -FSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTD--- 279
+ ++ +Q+ G++Y H+ +VHRD+K NLL+D+R N+KI DFGL+ + D
Sbjct: 114 RLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHF 173
Query: 280 VSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQF 339
+ + + N Y PE++ G EVD W CG +L L G F N
Sbjct: 174 LKTSCGSPN------YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEN----- 222
Query: 340 QRILSIMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRY 399
+P + K K + S + +A DL ++L
Sbjct: 223 ---------------------------IPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIV 255
Query: 400 DQDTRFTTTEALQHHYFTNEPKPQPLLLGP 429
D R T E QH +F P+ L + P
Sbjct: 256 DPVKRITIPEIRQHRWFQTH-LPRYLAVSP 284
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 114 bits (286), Expect = 2e-25
Identities = 74/265 (27%), Positives = 129/265 (47%), Gaps = 34/265 (12%)
Query: 173 SIREIKLLQQLN-HPNISLIHEIIV-----SDKNTISMGFQYMENDLSGMLMDKSIQFSD 226
++RE+KLL+ L HPNI + + + N + + + ME DLS ++ + + D
Sbjct: 69 TLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQ-RLED 127
Query: 227 SNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASN 286
++ + + Q+ L+Y+H ++H D+K NLL+++ LKI +FGL+ ++
Sbjct: 128 AHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDG 187
Query: 287 TNR--VITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILS 344
+ + ++WY+ PE+LL + VD W GC+L EL +F G + VD IL
Sbjct: 188 FIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQ 247
Query: 345 IMGSPTLEQWPKMLDMPWWFMLVPQISKTYKNVFFDEFSKVP------------QDALDL 392
I+G+P E ++ K Y +F +F +P +AL+L
Sbjct: 248 ILGTPPEETLQEIAS-----------QKVYNYIF--QFGNIPGRSFESILPGANPEALEL 294
Query: 393 ASKLLRYDQDTRFTTTEALQHHYFT 417
K+L +D R T +AL+H Y +
Sbjct: 295 LKKMLEFDPKKRITVEDALEHPYLS 319
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 114 bits (285), Expect = 3e-25
Identities = 89/298 (29%), Positives = 146/298 (48%), Gaps = 28/298 (9%)
Query: 129 FQPLAQVGEGTYGKVYKAENVHTGKLI-ALKRLRLEQERDGFPITSIREIKLLQQLNHPN 187
+Q ++G G Y +V++ +I ALK +R + RE+ +L+ L+H N
Sbjct: 37 YQIYQRMGRGKYSEVFEGRKDREKIVIKALKPVRKAK--------ICREVLILRNLSHKN 88
Query: 188 ISLIHEIIVSDKNTI-SMGFQYMENDLSGMLMDKSIQFSDSNIKHLMKQLFVGLQYLHQQ 246
I + +++V ++ I S+ F+Y+E++ + +K +I +Q+ L Y H
Sbjct: 89 IIKLMDVVVDPESQIYSLIFEYIEHEDYAKIFEKLCY---KDIVEYSRQILSALSYCHSM 145
Query: 247 QIVHRDIKGSNLLIDN-RGNLKITDFGLAKKLTDVSSPASNTN-RVITLWYRPPELLLGA 304
I+HRDIK N++I+ R LKI D+GLA + P + RV + +Y+ PELL+
Sbjct: 146 GIIHRDIKPQNMVINQARRELKIIDWGLA----EFYHPKKEYSVRVASRYYKGPELLVDY 201
Query: 305 TDYKYEVDCWGCGCLLVEL-FAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWW 363
Y Y +D W GC+L EL F F G + DQ +I I+G L+++ + M
Sbjct: 202 PYYDYSLDIWSFGCVLAELVFKKRPFFHGESNSDQLVKIARILGYTHLKKYVRKYKMA-- 259
Query: 364 FMLVPQISKTYKNVFFDEFSK-----VPQDALDLASKLLRYDQDTRFTTTEALQHHYF 416
L P+ + V F+ + +A+DL K+L YD R T E L+H F
Sbjct: 260 -PLNPKYEGVGERVLLSSFTPPGKTGLYTNAIDLLEKILIYDHQDRPTADECLRHPLF 316
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 114 bits (284), Expect = 4e-25
Identities = 81/283 (28%), Positives = 145/283 (50%), Gaps = 28/283 (9%)
Query: 108 SRNIFGKKPLALISFQDVKSSFQPLAQVGEGTYGKVYKAENVHTGKL---IALKRLRLEQ 164
+ +I+ L + F+D + ++G+G++G VY A+ L +A+K+L+
Sbjct: 3 NESIYSVLDLTQVIFED---RYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSS 59
Query: 165 E-RDGFPITSIREIKLLQQLN-HPNISLIHEIIVSDKNTISMGFQYMENDLSGMLMDKSI 222
+ + + +RE L++++ HP + + E + I + ++M+ +L + +
Sbjct: 60 KPKPKHELLKLRESLALRKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQG 119
Query: 223 Q-FSDSNIKHLMKQLFVGLQYLHQQQIVHRDIKGSNLL--------IDNRGNLKITDFGL 273
+ F+ +++ Q+ G++++H+ +HRDIK N+L I +R ++K+ DFGL
Sbjct: 120 RLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGL 179
Query: 274 AKKLTDVSSPASNTNRVITLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGS 333
A+ S P T V T WYR PELLL + Y + VD + GC++ E+++ +FPG
Sbjct: 180 ARPSVS-SDPL--TEYVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLKPLFPGR 236
Query: 334 NEVDQFQRILSIMGSP------TLEQW--PKMLDMPWWFMLVP 368
NE DQ R+ I+G+P TL W K L FML P
Sbjct: 237 NETDQLNRVCEILGNPGIDELDTLHYWSQAKELAKRLGFMLPP 279
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 114 bits (284), Expect = 4e-25
Identities = 84/291 (28%), Positives = 137/291 (46%), Gaps = 50/291 (17%)
Query: 135 VGEGTYGKVYKAENVHTGKLIALKRLRLEQERD-GFPITSIREIKLLQQLNHPNISLIHE 193
+G G++ KV A +V TG +A+K L + ++ G I REIK+L+ L HP+I +E
Sbjct: 25 LGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYE 84
Query: 194 IIVSDKNTISMGFQYMENDLSGMLMDKSIQ---FSDSNIKHLMKQLFVGLQYLHQQQIVH 250
+I + N I + +Y++ SG L D ++ + +HL +Q+ G++Y H+ IVH
Sbjct: 85 VIETP-NDIYVVMEYVK---SGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVH 140
Query: 251 RDIKGSNLLIDNRGNLKITDFGLAKKLTD---VSSPASNTNRVITLWYRPPELLLGATDY 307
RD+K N+L+D++ N+KI DFGL+ + D + + + N Y PE++ G Y
Sbjct: 141 RDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPN------YAAPEVISG-KPY 193
Query: 308 KYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTLEQWPKMLDMPWWFMLV 367
+VD W CG +L L G F N +
Sbjct: 194 GPDVDIWSCGVILYALLCGTLPFDDEN--------------------------------I 221
Query: 368 PQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTEALQHHYFTN 418
P + + K + + + A DL ++L D R + TE QH +F N
Sbjct: 222 PNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNN 272
>CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 301
Score = 113 bits (282), Expect = 7e-25
Identities = 81/254 (31%), Positives = 122/254 (47%), Gaps = 18/254 (7%)
Query: 176 EIKLLQQL-NHPNISLIHEIIVSDKNT---ISMGFQYMENDLSGMLMDKSIQFSDSNIKH 231
EIK L L NH I E++ S + + M F+ E DL G+L D+ + S I+
Sbjct: 58 EIKYLDVLTNHEQRRNIVEMLKSFETPEIRLGMVFKRYETDLFGILGDRQ-RLQPSTIQK 116
Query: 232 LMKQLFVGLQYLHQQQIVHRDIKGSNLLIDNRGNLKITDFGLAKKLTDVSSPASNTNRVI 291
MK L GLQ++H+ +HRDIK NLLID + I DFG V S + +
Sbjct: 117 YMKGLMEGLQFIHRMDYIHRDIKPENLLIDGE-TICIADFG-----ETVLSTSDKVVKPG 170
Query: 292 TLWYRPPELLLGATDYKYEVDCWGCGCLLVELFAGAAIFPGSNEVDQFQRILSIMGSPTL 351
TL Y E +LG + +D W C+L +F G+ +F ++ + I ++G+ T
Sbjct: 171 TLPYLTIEHILGYKENTKSMDIWAAACVLGAMFQGSHLFSQNSNLQTIHAIRLLLGNHTK 230
Query: 352 EQWPKMLDMPWW--FMLVPQISKTYKNVFFDEFSKVPQDALDLASKLLRYDQDTRFTTTE 409
E WP+M +P L P KT F + + ++A DL ++++YD R ++
Sbjct: 231 ETWPEMDKLPLMQSIELPPVGEKT-----FSKIENITKEAADLMEQMMKYDPTKRLMASQ 285
Query: 410 ALQHHYFTNEPKPQ 423
L H YF E Q
Sbjct: 286 VLNHEYFKKEASAQ 299
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,899,716
Number of Sequences: 60738
Number of extensions: 1263872
Number of successful extensions: 8488
Number of sequences better than 1.0e-05: 1661
Number of HSP's better than 0.0 without gapping: 567
Number of HSP's successfully gapped in prelim test: 1094
Number of HSP's that attempted gapping in prelim test: 4835
Number of HSP's gapped (non-prelim): 2022
length of query: 455
length of database: 30,389,216
effective HSP length: 110
effective length of query: 345
effective length of database: 23,708,036
effective search space: 8179272420
effective search space used: 8179272420
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)