ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3139 good AR KOG2190 General function prediction only PolyC-binding proteins alphaCP-1 and related KH domain proteins
r_klactV3139 good AR KOG2190 RNA processing and modification PolyC-binding proteins alphaCP-1 and related KH domain proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3139 1088810 1089958 383
(383 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBL032w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 223 5e-58
SPCC757.09c [AR] KOG2190 PolyC-binding proteins alphaCP-1 and re... 106 7e-23
Hs14670369 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 88 2e-17
Hs10092617 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 78 2e-14
Hs14141168 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 77 6e-14
Hs14141166 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 75 1e-13
Hs5453854 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 75 2e-13
YBR233w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 70 5e-12
At5g04430 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and rel... 70 5e-12
7296507 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 70 7e-12
Hs14670371 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 67 6e-11
Hs20539507 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains... 58 3e-08
Hs14165437 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnR... 57 3e-08
Hs14165435 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnR... 57 3e-08
CE27461 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 56 8e-08
At1g14170 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 55 1e-07
HsM5729882 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains... 54 3e-07
Hs5729884 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains ... 53 9e-07
Hs21361352 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains... 52 1e-06
Hs5803195 [T] KOG2279 Kinase anchor protein AKAP149 contains KH ... 49 1e-05
>YBL032w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 381
Score = 223 bits (567), Expect = 5e-58
Identities = 140/331 (42%), Positives = 194/331 (58%), Gaps = 31/331 (9%)
Query: 40 NEVNEINNDTNSQVNNGN---------NITFHVLVSLKEAAKIIGPQGNTIETIRRENDI 90
N N ++D S G I +L+SLKEAAKIIG +G+TI IR N +
Sbjct: 16 NNTNGGSSDAGSAATGGAPVVGTTAQPTINHRLLLSLKEAAKIIGTKGSTISRIRAANAV 75
Query: 91 KIGISPREKSCSDRLLNVSGPPRQVANSLGQVLRVLT---------TDYEPEEHVFKH-L 140
KIGIS + CSDR+L+ +G VAN++G ++ VL + E EEH + H L
Sbjct: 76 KIGISEKVPGCSDRILSCAGNVINVANAIGDIVDVLNKRNPENEDAAEGEAEEHYYFHFL 135
Query: 141 RFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVASKH 200
+LP SK+EI D ++ + IG +RLI N ISS+IG+ GA IK LI H VK+VASK
Sbjct: 136 NHILPAPSKDEIRDLQQLEDIGYVRLIVANSHISSIIGKAGATIKSLINKHGVKIVASKD 195
Query: 201 FLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVPPRTLPRYYPHSKHTKEIQVSQT 260
FLP S +R++EIQGFP S+ N + EI+E+ I DV V T Y+PH K + S +
Sbjct: 196 FLPASDERIIEIQGFPGSITNVLIEISEI-ILSDVDVRFSTERSYFPHLKKSSGEPTSPS 254
Query: 261 --------LAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQDPTENGD---RIFTVWGN 309
L IP+ +VGA++G G NRI NL+ FTKT IV+ + ++ D R F +
Sbjct: 255 TSSNTRIELKIPELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDENFRKFIITSK 314
Query: 310 DQKSVKLAQTMLLKNLEVEKKRREEHEASLK 340
K+VKLA++MLLKNL E ++RE ++ L+
Sbjct: 315 FPKNVKLAESMLLKNLNTEIEKRENYKRKLE 345
>SPCC757.09c [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 398
Score = 106 bits (264), Expect = 7e-23
Identities = 80/322 (24%), Positives = 144/322 (43%), Gaps = 67/322 (20%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T L+S +EA IIG G + +R ++K G++ + DR+L +SGP V +
Sbjct: 94 LTLRALLSTREAGIIIGKAGKNVAELRSTTNVKAGVTKAVPNVHDRVLTISGPLENVVRA 153
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
++ + + P + + P K LRL+ + + S+IG
Sbjct: 154 YRFIIDIFAKNSTN------------PDGTPSDANTPRK------LRLLIAHSLMGSIIG 195
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQD----- 233
+ G +IK + + + +++ASK LP S +R +EI G ++ I EI + I D
Sbjct: 196 RNGLRIKLIQDKCSCRMIASKDMLPQSTERTVEIHGTVDNLHAAIWEIGKCLIDDWERGA 255
Query: 234 -------------------DVHVPPRTLPRYYPHSKHTKEI------------------- 255
P + P P + + I
Sbjct: 256 GTVFYNPVSRLTQPLPSLASTASPQQVSPPAAPSTTSGEAIPENFVSYGAQVFPATQMPF 315
Query: 256 ----QVSQTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQDP-TENGDRIFTVWGND 310
+V+Q ++IP + VG ++G GG++I+ +R+ + +KI I ++P E G+R+FT+ G
Sbjct: 316 LQQPKVTQNISIPADMVGCIIGRGGSKISEIRRTSGSKISIAKEPHDETGERMFTITGTH 375
Query: 311 QKSVKLAQTMLLKNLEVEKKRR 332
+++ K A +L + LE+EK RR
Sbjct: 376 EENEK-ALFLLYQQLEMEKDRR 396
>Hs14670369 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 403
Score = 87.8 bits (216), Expect = 2e-17
Identities = 77/321 (23%), Positives = 138/321 (42%), Gaps = 75/321 (23%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T +L+ KE IIG +G T++ IR ++ +I IS E SC +R+ ++G V ++
Sbjct: 18 LTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITIS--EGSCPERITTITGSTAAVFHA 75
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
+ + L D PA+ + P LRL+ Q S+IG
Sbjct: 76 VSMIAFKLDED------------LCAAPANGGNVSRPPV-----TLRLVIPASQCGSLIG 118
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVP 238
+ G KIK++ ET ++ + LP+S +R + + G P ++ C+ +I + ++ P
Sbjct: 119 KAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES----P 174
Query: 239 PR--TLPRYYPH-------------------------SKHTKEIQV-------------- 257
P+ T+P Y+P ++ TK Q+
Sbjct: 175 PKGATIP-YHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVP 233
Query: 258 ---------SQTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQDPTENGDRIFTVWG 308
SQ +P + +G ++G G++I+ +R+ + I IG G+R T+ G
Sbjct: 234 GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITG 293
Query: 309 NDQKSVKLAQTMLLKNLEVEK 329
+ S+ LAQ ++ LE K
Sbjct: 294 S-PVSIALAQYLITACLETAK 313
>Hs10092617 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 339
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/210 (27%), Positives = 103/210 (48%), Gaps = 29/210 (13%)
Query: 51 SQVNNGN---NITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLN 107
S+V+ G +T +L+ KE IIG +G T++ +R E+ +I IS E +C +R++
Sbjct: 3 SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS--EGNCPERIVT 60
Query: 108 VSGPPRQVANSLGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLI 167
++GP + + + Y+ EE + + P SK + LRL+
Sbjct: 61 ITGPTDAIFKAFAMIA------YKFEEDIINSMSNS-PATSKPPV----------TLRLV 103
Query: 168 CTNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIA 227
Q S+IG+ G+KIK++ E+ ++ + LP+S +R + I G P ++ C+ +I
Sbjct: 104 VPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQIC 163
Query: 228 ELFIQDDVHVPPR--TLPRYYPHSKHTKEI 255
+ ++ PP+ T+P Y P T I
Sbjct: 164 VVMLES----PPKGATIP-YRPKPASTPVI 188
Score = 53.1 bits (126), Expect = 7e-07
Identities = 39/168 (23%), Positives = 79/168 (46%), Gaps = 12/168 (7%)
Query: 164 LRLICTNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCI 223
+RL+ ++ S+IG++G +KK+ E ++ S+ P+ R++ I G ++
Sbjct: 16 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 72
Query: 224 NEIAELFIQDDVHVPPRTLPRYYPHSKHTKEIQVSQTLAIPKEFVGALLGVGGNRIANLR 283
IA F +D ++ +S T + V+ L +P G+L+G GG++I +R
Sbjct: 73 AMIAYKFEEDIINS--------MSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIR 124
Query: 284 KFTKTKIVIGQDPTENG-DRIFTVWGNDQKSVKLAQTMLLKNLEVEKK 330
+ T ++ + D N +R T+ G ++ + + + LE K
Sbjct: 125 ESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPK 172
>Hs14141168 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 366
Score = 76.6 bits (187), Expect = 6e-14
Identities = 48/187 (25%), Positives = 90/187 (47%), Gaps = 21/187 (11%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T +L+ KE IIG +G +++ +R E+ +I IS E +C +R++ ++GP + +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKA 71
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
++ L D + PP + LRL+ Q S+IG
Sbjct: 72 FAMIIDKLEEDISSS--MTNSTAASRPPVT---------------LRLVVPASQCGSLIG 114
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVP 238
+ G KIK++ E+ ++ + LP+S +R + I G P S+ C+ +I + ++ P
Sbjct: 115 KGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSP 174
Query: 239 PR--TLP 243
P+ T+P
Sbjct: 175 PKGVTIP 181
>Hs14141166 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 362
Score = 75.5 bits (184), Expect = 1e-13
Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 22/192 (11%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T +L+ KE IIG +G +++ +R E+ +I IS E +C +R++ ++GP + +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKA 71
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
++ L D + PP + LRL+ Q S+IG
Sbjct: 72 FAMIIDKLEEDISSS--MTNSTAASRPPVT---------------LRLVVPASQCGSLIG 114
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQD---DV 235
+ G KIK++ E+ ++ + LP+S +R + I G P S+ C+ +I + ++ V
Sbjct: 115 KGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGV 174
Query: 236 HVPPRTLPRYYP 247
+P R P P
Sbjct: 175 TIPYRPKPSSSP 186
>Hs5453854 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 356
Score = 74.7 bits (182), Expect = 2e-13
Identities = 46/174 (26%), Positives = 84/174 (47%), Gaps = 19/174 (10%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T +L+ KE IIG +G +++ IR E+ +I IS E +C +R++ ++GP + +
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKA 71
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
++ L D + PP + LRL+ Q S+IG
Sbjct: 72 FAMIIDKLEEDINSS--MTNSTAASRPPVT---------------LRLVVPATQCGSLIG 114
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQ 232
+ G KIK++ E+ ++ + LP+S +R + I G P SV C+ +I + ++
Sbjct: 115 KGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLE 168
>YBR233w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 413
Score = 70.1 bits (170), Expect = 5e-12
Identities = 50/203 (24%), Positives = 99/203 (48%), Gaps = 23/203 (11%)
Query: 46 NNDTNSQVNNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRL 105
+ND +S N +++ +L +K A+ I+G +G TI I+ E +I IS + +R+
Sbjct: 54 DNDHDSPDNVPSDVHLRMLCLVKHASLIVGHKGATISRIKSETSARINISNNIRGVPERI 113
Query: 106 LNVSGPPRQVANSLGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLR 165
+ V G VA + G ++R L ++ E+ + E+IE ++
Sbjct: 114 VYVRGTCDDVAKAYGMIVRALLEEHGNED-------------NGEDIEI--------SIN 152
Query: 166 LICTNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINE 225
L+ + + +IG++G++++++ + KL AS + L S DR+L I G P ++
Sbjct: 153 LLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQLLLSNDRILTINGVPDAIHIATFY 212
Query: 226 IAELFIQDDVHVPPRTLPR--YY 246
I++ + + P + + R YY
Sbjct: 213 ISQTLLNFQMESPQKNVKRSIYY 235
>At5g04430 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and related KH
domain proteins
Length = 313
Score = 70.1 bits (170), Expect = 5e-12
Identities = 68/292 (23%), Positives = 124/292 (42%), Gaps = 45/292 (15%)
Query: 64 LVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREK---SCSDRLLNVSGPPRQVANSLG 120
LVS A +IG G+TI + ++ +I +S ++ +DR++ +SG ++V N L
Sbjct: 40 LVSNAAAGSVIGKGGSTITEFQAKSGARIQLSRNQEFFPGTTDRIIMISGSIKEVVNGLE 99
Query: 121 QVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIGQQ 180
+L L ++ E+ E+E + +RL+ N +IG+
Sbjct: 100 LILDKLHSELHAEDG--------------NEVEPRRR------IRLVVPNSSCGGIIGKG 139
Query: 181 GAKIKKLIETHT--VKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDD---- 234
GA IK IE +K+ + DR++ + G I+ I +DD
Sbjct: 140 GATIKSFIEESKAGIKISPLDNTFYGLSDRLVTLSGTFEEQMRAIDLILAKLTEDDHYSQ 199
Query: 235 -VHVPPRTLPRYYP-----------HSKHTKEIQVSQTLAIPKEFVGALLGVGGNRIANL 282
VH P Y + H +E + T+ + E +G +LG GG I +
Sbjct: 200 NVHSPYSYAAGYNSVNYAPNGSGGKYQNHKEEASTTVTIGVADEHIGLVLGRGGRNIMEI 259
Query: 283 RKFTKTKIVI---GQDPTENGDRIFTVWGNDQKSVKLAQTMLLKNLEVEKKR 331
+ T +I I G + DR ++ G Q++++ A+TM+ + ++ +R
Sbjct: 260 TQMTGARIKISDRGDFMSGTTDRKVSITG-PQRAIQQAETMIKQKVDSATER 310
>7296507 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 386
Score = 69.7 bits (169), Expect = 7e-12
Identities = 69/271 (25%), Positives = 115/271 (41%), Gaps = 35/271 (12%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T +++ KE IIG +G + R E+ KI IS + SC +R++ VSG N+
Sbjct: 24 LTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINIS--DGSCPERIVTVSG----TTNA 77
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
+ ++T +E F + K +I +RLI Q S+IG
Sbjct: 78 IFSAFTLITKKFEEWCSQFNDVG----KVGKTQIP----------IRLIVPASQCGSLIG 123
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVP 238
+ G+KIK++ +T + + LP+S +R + + G + CI +I + ++ P
Sbjct: 124 KSGSKIKEIRQTTGCSIQVASEMLPNSTERAVTLSGSAEQITQCIYQICLVMLES----P 179
Query: 239 PR--TLPRYYPHSKHTKEIQVS--QTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQ 294
PR T+P Y P + T + ++ Q I + V N +A+L + G
Sbjct: 180 PRGATIP-YRPKPQVTGPVILANGQAFTIQGNYAVPTQEVAKNPLASLAALG----LAGM 234
Query: 295 DPTENGDRIFTVWGNDQKSVKLAQTMLLKNL 325
+P G T G S QT NL
Sbjct: 235 NPASTGGINHT--GELSASAARCQTDFQSNL 263
>Hs14670371 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 369
Score = 66.6 bits (161), Expect = 6e-11
Identities = 64/286 (22%), Positives = 117/286 (40%), Gaps = 73/286 (25%)
Query: 94 ISPREKSCSDRLLNVSGPPRQVANSLGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIE 153
I+ E SC +R+ ++G V +++ + L D PA+ +
Sbjct: 17 ITISEGSCPERITTITGSTAAVFHAVSMIAFKLDED------------LCAAPANGGNVS 64
Query: 154 DPEKWKQIGNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQ 213
P LRL+ Q S+IG+ G KIK++ ET ++ + LP+S +R + +
Sbjct: 65 RPPV-----TLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVS 119
Query: 214 GFPTSVANCINEIAELFIQDDVHVPPR--TLPRYYPH----------------------- 248
G P ++ C+ +I + ++ PP+ T+P Y+P
Sbjct: 120 GVPDAIILCVRQICAVILES----PPKGATIP-YHPSLSLGTVLLSANQGFSVQGQYGAV 174
Query: 249 --SKHTKEIQV-----------------------SQTLAIPKEFVGALLGVGGNRIANLR 283
++ TK Q+ SQ +P + +G ++G G++I+ +R
Sbjct: 175 TPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIR 234
Query: 284 KFTKTKIVIGQDPTENGDRIFTVWGNDQKSVKLAQTMLLKNLEVEK 329
+ + I IG G+R T+ G+ S+ LAQ ++ LE K
Sbjct: 235 QMSGAHIKIGNQAEGAGERHVTITGS-PVSIALAQYLITACLETAK 279
>Hs20539507 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 579
Score = 57.8 bits (138), Expect = 3e-08
Identities = 63/319 (19%), Positives = 129/319 (39%), Gaps = 42/319 (13%)
Query: 44 EINNDTNSQVNNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSC-- 101
EI + + I +L ++IG +G ++ I ++ D KI ISP ++
Sbjct: 262 EIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLY 321
Query: 102 -SDRLLNVSGPPRQVANSLGQVLRVLTTDYEP-------EEHVFKHLRF----------- 142
+R + V G A + ++++ + YE + H+ L
Sbjct: 322 NPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSG 381
Query: 143 MLPPASKEEIEDPEKWKQI-----GNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVA 197
M PP S + Q + L + ++IG+QG IK+L +
Sbjct: 382 MPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKI 441
Query: 198 SKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVPPRTLPRYYPHSKHTKEIQV 257
+ PD+K R++ I G P + I I+++ V P+ +E+++
Sbjct: 442 APAEAPDAKVRMVIITGPPEAQFKAQGRIYGK-IKEENFVSPK------------EEVKL 488
Query: 258 SQTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQD--PTENGDRIFTVWGNDQKSVK 315
+ +P G ++G GG + L+ + ++V+ +D P EN + + G+ + +
Sbjct: 489 EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFY-ACQ 547
Query: 316 LAQTMLLKNLEVEKKRREE 334
+AQ + + L K+ +++
Sbjct: 548 VAQRKIQEILTQVKQHQQQ 566
>Hs14165437 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP contains KH
domain
Length = 464
Score = 57.4 bits (137), Expect = 3e-08
Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 11/187 (5%)
Query: 54 NNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPR 113
N + +L+ K A +IG G I+ +R D +S + S +R+L++S
Sbjct: 38 NTDEMVELRILLQSKNAGAVIGKGGKNIKALR--TDYNASVSVPDSSGPERILSISAD-- 93
Query: 114 QVANSLGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGN-----LRLIC 168
++G++L+ + E + P + +E G+ LRL+
Sbjct: 94 --IETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLI 151
Query: 169 TNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAE 228
+IG +GAKIK+L E + + P S DRV+ I G P V CI I +
Sbjct: 152 HQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILD 211
Query: 229 LFIQDDV 235
L + +
Sbjct: 212 LISESPI 218
>Hs14165435 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP contains KH
domain
Length = 463
Score = 57.4 bits (137), Expect = 3e-08
Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 11/187 (5%)
Query: 54 NNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPR 113
N + +L+ K A +IG G I+ +R D +S + S +R+L++S
Sbjct: 38 NTDEMVELRILLQSKNAGAVIGKGGKNIKALR--TDYNASVSVPDSSGPERILSISAD-- 93
Query: 114 QVANSLGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGN-----LRLIC 168
++G++L+ + E + P + +E G+ LRL+
Sbjct: 94 --IETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLI 151
Query: 169 TNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAE 228
+IG +GAKIK+L E + + P S DRV+ I G P V CI I +
Sbjct: 152 HQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILD 211
Query: 229 LFIQDDV 235
L + +
Sbjct: 212 LISESPI 218
>CE27461 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 451
Score = 56.2 bits (134), Expect = 8e-08
Identities = 42/156 (26%), Positives = 73/156 (45%), Gaps = 22/156 (14%)
Query: 59 ITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSCSDRLLNVSGPPRQVANS 118
+T +L+ KE IIG +G+ I+ IR E+ KI IS + SC +R++ ++G
Sbjct: 72 LTIRLLMQGKEVGSIIGKKGDQIKKIREESGAKINIS--DGSCPERIVTITG----TLGV 125
Query: 119 LGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIG 178
+G+ ++ +E + +L P S K +R+I Q S+IG
Sbjct: 126 IGKAFNMVCNKFEED--------MLLLPNSVP--------KPPITMRVIVPATQCGSLIG 169
Query: 179 QQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQG 214
+ G+KIK + E + + LP S +R + + G
Sbjct: 170 KGGSKIKDIREATGASIQVASEMLPHSTERAVTLSG 205
Score = 50.4 bits (119), Expect = 4e-06
Identities = 40/179 (22%), Positives = 86/179 (47%), Gaps = 18/179 (10%)
Query: 155 PEKWKQIGNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQG 214
P + +RL+ ++ S+IG++G +IKK+ E K+ S P +R++ I G
Sbjct: 65 PSTTSLVLTIRLLMQGKEVGSIIGKKGDQIKKIREESGAKINISDGSCP---ERIVTITG 121
Query: 215 FPTSVANCINEIAELFIQDDVHVPPRTLPRYYPHSKHTKEIQVSQTLAIPKEFVGALLGV 274
+ N + F ++D+ + P ++P+ ++ + +P G+L+G
Sbjct: 122 TLGVIGKAFNMVCNKF-EEDMLLLPNSVPK----------PPITMRVIVPATQCGSLIGK 170
Query: 275 GGNRIANLRKFTKTKIVIGQDPTENG-DRIFTVWGN-DQKSVKLA--QTMLLKNLEVEK 329
GG++I ++R+ T I + + + +R T+ G D ++++ L KN +++K
Sbjct: 171 GGSKIKDIREATGASIQVASEMLPHSTERAVTLSGTADAINLRITPQPLELQKNFQLQK 229
>At1g14170 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 479
Score = 55.5 bits (132), Expect = 1e-07
Identities = 65/302 (21%), Positives = 120/302 (39%), Gaps = 37/302 (12%)
Query: 37 NSYNEVNEINNDTNSQVNNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISP 96
N ++ ++++T+ V + + L +K+ IIG G + IR E + I+
Sbjct: 22 NGGSKRRNLHDETDQNVIASEDTVYRYLCPVKKTGSIIGKGGEIAKQIRSETKSNMRINE 81
Query: 97 REKSCSDRLLNVSGPPRQVANSLGQVLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPE 156
C +R++ + ++ N G ++ + +FK ++ A +++ D +
Sbjct: 82 ALPGCEERVVTMYSTNEEL-NHFGDDGELVCPALDA---LFKVHDMVVADADQDDGTDDD 137
Query: 157 K---WKQIGNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVASKHFLPD-----SKDR 208
KQ +R++ + QI VIG+ G I+ L ++ K LP S D
Sbjct: 138 NDLGEKQTVTVRMLVPSDQIGCVIGKGGQVIQNLRNDTNAQIRVIKDHLPACALTLSHDE 197
Query: 209 VLEIQGFPTSVANCINEIAELF--------------IQDDVHVPPRTLPRYYPHSKHTKE 254
+L I G P V + ++A L +H P L S H +
Sbjct: 198 LLLIIGEPLVVREALYQVASLLHDNPSRFQHLLLSSSSSSMHQPGAMLMSAALTSSH-RN 256
Query: 255 IQVSQTLAIPKEF----------VGALLGVGGNRIANLRKFTKTKIVIGQDPTENGDRIF 304
V + +A +EF VG ++G GG I +R+ T I + T++ D I
Sbjct: 257 YAVRRDIADAREFCVCFICPAENVGGVIGKGGGFINQIRQETGATIRVNTSETDDDDCII 316
Query: 305 TV 306
+
Sbjct: 317 FI 318
>HsM5729882 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 577
Score = 54.3 bits (129), Expect = 3e-07
Identities = 56/323 (17%), Positives = 128/323 (39%), Gaps = 42/323 (13%)
Query: 44 EINNDTNSQVNNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSC-- 101
EI + + + +L ++IG +G ++ + ++ + KI IS +
Sbjct: 262 EIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLY 321
Query: 102 -SDRLLNVSGPPRQVANSLGQVLRVLTTDYEPEEHVFKHLRFMLP----------PASKE 150
+R + V G + ++++ + YE + ++P PAS
Sbjct: 322 NPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSS 381
Query: 151 EIEDPE-------------KWKQIGNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVA 197
+ P + + +++ + ++IG++G IK+L + +
Sbjct: 382 AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKI 441
Query: 198 SKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVPPRTLPRYYPHSKHTKEIQV 257
+ PDSK R++ I G P + I +++ P +E+++
Sbjct: 442 APPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGP-------------KEEVKL 488
Query: 258 SQTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQD--PTENGDRIFTVWGNDQKSVK 315
+ +P G ++G GG + L+ T ++V+ +D P EN I + G+ S +
Sbjct: 489 ETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYAS-Q 547
Query: 316 LAQTMLLKNLEVEKKRREEHEAS 338
+AQ + L K++ ++ +++
Sbjct: 548 MAQRKIRDILAQVKQQHQKGQSN 570
>Hs5729884 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 556
Score = 52.8 bits (125), Expect = 9e-07
Identities = 65/297 (21%), Positives = 127/297 (41%), Gaps = 45/297 (15%)
Query: 63 VLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKS-CSDRLLNVSGPPRQVANSLGQ 121
+LV + IIG +G TI+ I ++ ++ I +E S +++ + + P + +
Sbjct: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
Query: 122 VLRVLTTDYEPEEHVFKHLRFMLPPASKEEIEDPEKWKQIGNLRLICTNPQISSVIGQQG 181
+L ++ ++E ++ + ++I L+++ N + +IG++G
Sbjct: 258 ILEIM----------------------QKEADETKLAEEI-PLKILAHNGLVGRLIGKEG 294
Query: 182 AKIKKL-IETHTVKLVASKHFLP-DSKDRVLEIQGFPTSVANC----INEIAELFIQDDV 235
+KK+ ET T ++S L + +R + ++G + A+ + ++ E F D +
Sbjct: 295 RNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDML 354
Query: 236 HVPPRT--LPRYYPHSK-------HTKEIQVSQTLAIPKEFVGALLGVGGNRIANLRKFT 286
V + YPH + H+ Q L IP + VGA++G G I L +F
Sbjct: 355 AVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFA 414
Query: 287 KTKIVIGQDPTENGD---RIFTVWGNDQKSVKLAQTMLLKNLEVEKKRREEHEASLK 340
I I P E D R+ + G + K AQ + L+ E + E L+
Sbjct: 415 GASIKIA--PAEGPDVSERMVIITGPPEAQFK-AQGRIFGKLKEENFFNPKEEVKLE 468
>Hs21361352 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 577
Score = 52.0 bits (123), Expect = 1e-06
Identities = 56/323 (17%), Positives = 126/323 (38%), Gaps = 42/323 (13%)
Query: 44 EINNDTNSQVNNGNNITFHVLVSLKEAAKIIGPQGNTIETIRRENDIKIGISPREKSC-- 101
EI + + + L ++IG +G ++ + ++ + KI IS +
Sbjct: 262 EIMHKEAKDTKTADEVPLKTLAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLY 321
Query: 102 -SDRLLNVSGPPRQVANSLGQVLRVLTTDYEPEEHVFKHLRFMLP----------PASKE 150
+R + V G + ++++ + YE + + P PAS
Sbjct: 322 NPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLTPGLNLAAVGLFPASSS 381
Query: 151 EIEDPE-------------KWKQIGNLRLICTNPQISSVIGQQGAKIKKLIETHTVKLVA 197
+ P + + +++ + ++IG++G IK+L + +
Sbjct: 382 AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKI 441
Query: 198 SKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQDDVHVPPRTLPRYYPHSKHTKEIQV 257
+ PDSK R++ I G P + I +++ P +E+++
Sbjct: 442 APPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGP-------------KEEVKL 488
Query: 258 SQTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVIGQD--PTENGDRIFTVWGNDQKSVK 315
+ +P G ++G GG + L+ T ++V+ +D P EN I + G+ S +
Sbjct: 489 ETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYAS-Q 547
Query: 316 LAQTMLLKNLEVEKKRREEHEAS 338
+AQ + L K++ ++ +++
Sbjct: 548 MAQRKIRDILAQVKQQHQKGQSN 570
>Hs5803195 [T] KOG2279 Kinase anchor protein AKAP149 contains KH and Tudor
RNA-binding domains
Length = 606
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/172 (25%), Positives = 78/172 (44%), Gaps = 28/172 (16%)
Query: 173 ISSVIGQQGAKIKKLIETHTVKLVASKHFLPDSKDRVLEIQGFPTSVANCINEIAELFIQ 232
+ +IG+QGA IK+L + ++ + D +RVL I GFP V I ++
Sbjct: 64 VKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAKAAIHQIL-- 119
Query: 233 DDVHVPPRTLPRYYPHSKHTKEIQVSQTLAIPKEFVGALLGVGGNRIANLRKFTKTKIVI 292
T+ VS+ L++P+ VG ++G GG I ++ K + KI
Sbjct: 120 -------------------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC 160
Query: 293 GQDP--TENGDRIFTVWGNDQKSVKLAQTMLLKNL--EVEKKRREEHEASLK 340
++ T R+ + G QK V A+ ++L+ + + E ++R H A +
Sbjct: 161 DKESEGTLLLSRLIKISGT-QKEVAAAKHLILEKVSEDEELRKRIAHSAETR 211
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,057,991
Number of Sequences: 60738
Number of extensions: 849681
Number of successful extensions: 2425
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2335
Number of HSP's gapped (non-prelim): 62
length of query: 383
length of database: 30,389,216
effective HSP length: 108
effective length of query: 275
effective length of database: 23,829,512
effective search space: 6553115800
effective search space used: 6553115800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)