ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3240 check: MH BK KOG1472 Chromatin structure and dynamics Histone acetyltransferase SAGA/ADA, catalytic subunit PCAF/GCN5 and related proteins
r_klactV3240 check: MH BK KOG1472 Transcription Histone acetyltransferase SAGA/ADA, catalytic subunit PCAF/GCN5 and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3240 1118642 1122541 1300
(1300 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR081c [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalyti... 937 0.0
SPBC25H2.11c [BK] KOG1472 Histone acetyltransferase SAGA/ADA cat... 295 4e-79
Hs13899209 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catal... 69 6e-11
Hs7304919 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI lar... 66 3e-10
YGR252w [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalyti... 65 7e-10
At3g19040 [K] KOG0008 Transcription initiation factor TFIID subu... 65 7e-10
Hs20357588_1 [K] KOG0008 Transcription initiation factor TFIID s... 64 2e-09
Hs20357585_1 [K] KOG0008 Transcription initiation factor TFIID s... 64 2e-09
At1g32750 [K] KOG0008 Transcription initiation factor TFIID subu... 62 5e-09
Hs11321642 [R] KOG0955 PHD finger protein BR140/LIN-49 62 6e-09
7298896 [K] KOG0008 Transcription initiation factor TFIID subuni... 62 6e-09
SPAC1952.05 [BK] KOG1472 Histone acetyltransferase SAGA/ADA cata... 61 1e-08
Hs6382076 [BK] KOG1472 Histone acetyltransferase SAGA/ADA cataly... 61 1e-08
YLR399c [K] KOG1474 Transcription initiation factor TFIID subuni... 60 2e-08
Hs14971411 [O] KOG2177 Predicted E3 ubiquitin ligase 60 2e-08
YDL070w [K] KOG1474 Transcription initiation factor TFIID subuni... 60 2e-08
Hs21071050 [BK] KOG0386 Chromatin remodeling complex SWI/SNF com... 60 2e-08
Hs21071048 [BK] KOG0386 Chromatin remodeling complex SWI/SNF com... 60 2e-08
Hs20555413 [R] KOG0955 PHD finger protein BR140/LIN-49 60 2e-08
CE19384 [K] KOG1474 Transcription initiation factor TFIID subuni... 60 2e-08
CE24921 [R] KOG1632 Uncharacterized PHD Zn-finger protein 60 3e-08
CE15910 [R] KOG1632 Uncharacterized PHD Zn-finger protein 60 3e-08
CE15909 [R] KOG1632 Uncharacterized PHD Zn-finger protein 60 3e-08
At2g34900 [K] KOG1474 Transcription initiation factor TFIID subu... 60 3e-08
7294564 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalyti... 59 4e-08
Hs7304923 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI lar... 59 7e-08
7290870 [K] KOG1474 Transcription initiation factor TFIID subuni... 59 7e-08
Hs11426183 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catal... 58 9e-08
Hs10835101 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catal... 58 9e-08
CE05553 [BK] KOG0386 Chromatin remodeling complex SWI/SNF compon... 58 9e-08
ECU10g1430 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catal... 58 1e-07
7302099 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large... 57 1e-07
Hs11067749 [K] KOG1474 Transcription initiation factor TFIID sub... 57 2e-07
YKR008w [BK] KOG1827 Chromatin remodeling complex RSC subunit RS... 57 2e-07
Hs4757866 [R] KOG0955 PHD finger protein BR140/LIN-49 57 2e-07
Hs21071056 [BK] KOG0386 Chromatin remodeling complex SWI/SNF com... 57 2e-07
CE27187 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large... 57 2e-07
7304241 [R] KOG0955 PHD finger protein BR140/LIN-49 57 2e-07
Hs15295343 [R] KOG0955 PHD finger protein BR140/LIN-49 56 3e-07
7294205 [BK] KOG0386 Chromatin remodeling complex SWI/SNF compon... 56 4e-07
Hs7019345 [K] KOG1828 IRF-2-binding protein CELTIX-1 contains BR... 55 6e-07
CE05310 [BK] KOG1827 Chromatin remodeling complex RSC subunit RS... 55 7e-07
At1g20670 [R] KOG0955 PHD finger protein BR140/LIN-49 55 7e-07
Hs7304921 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI lar... 55 9e-07
Hs14971413 [O] KOG2177 Predicted E3 ubiquitin ligase 55 9e-07
At3g01770 [K] KOG1474 Transcription initiation factor TFIID subu... 55 9e-07
Hs4826806 [K] KOG1474 Transcription initiation factor TFIID subu... 54 1e-06
Hs4557557 [K] KOG1778 CREB binding protein/P300 and related TAZ ... 54 1e-06
Hs4502453 [K] KOG1474 Transcription initiation factor TFIID subu... 54 1e-06
Hs14670392 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI la... 54 2e-06
ECU08g1640 [K] KOG1474 Transcription initiation factor TFIID sub... 54 2e-06
At3g52280 [K] KOG1474 Transcription initiation factor TFIID subu... 54 2e-06
SPAC631.02 [K] KOG1474 Transcription initiation factor TFIID sub... 54 2e-06
Hs4758056 [K] KOG1778 CREB binding protein/P300 and related TAZ ... 54 2e-06
At1g76380 [R] KOG0955 PHD finger protein BR140/LIN-49 54 2e-06
7295327 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalyti... 54 2e-06
Hs17449320 [O] KOG2177 Predicted E3 ubiquitin ligase 53 3e-06
Hs14971415 [O] KOG2177 Predicted E3 ubiquitin ligase 53 3e-06
Hs7657218 [K] KOG1474 Transcription initiation factor TFIID subu... 53 4e-06
Hs19718731 [K] KOG1474 Transcription initiation factor TFIID sub... 53 4e-06
Hs14670390 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI la... 53 4e-06
CE18461 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large... 53 4e-06
YIL126w [BK] KOG0386 Chromatin remodeling complex SWI/SNF compon... 52 8e-06
>YBR081c [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 1332
Score = 937 bits (2423), Expect = 0.0
Identities = 564/1375 (41%), Positives = 782/1375 (56%), Gaps = 134/1375 (9%)
Query: 2 ITSYQRSDAAAILRTIQKLFADDVFKKHLNPSQXXXXXXXXXXPDQESKTLIWDAFLSGK 61
I +YQR++A A+L+ +KLF + F +L Q +E K WD FL G
Sbjct: 7 IKNYQRTNAKALLKLTEKLFNKNFFDLYLTSQQLVVLEYLLSISSEEDKLKAWDYFLKGN 66
Query: 62 LELFVELNTTLNATSDKGATNDLVAATRLPSLSTQQQPQASSGLSRTGTPLHXXXXXXXX 121
+ L VE + L + TR +S+Q ++ + T
Sbjct: 67 IALNVEKSFPLTQEEEHHGAVSPAVDTRSDDVSSQTIKDNNNTNTNTSISNENHVENEIE 126
Query: 122 XXXXXXXXX---------------------LEQLKAQLDGLDFIGNLSMKVRYVVWEHGL 160
LE LK Q+ G FIGNLS+K+RYV+W+ +
Sbjct: 127 DKGDNAIANEDNFVNNDESDNVEEDLFKLDLEDLKQQISGTRFIGNLSLKIRYVLWQCAI 186
Query: 161 TLLE-------PETSSEYLLLDTDNDSAVIEDGSNNTLIDQSAVPNSSTLPTNDTAPLTM 213
+ E +EY LLD + E G N P
Sbjct: 187 DYIYCDRNEFGDENDTEYTLLDVEEKEEE-EIGKNEK-------------------PQNK 226
Query: 214 KEVSKNSENKEGSXXXXXXXXXXXXXXXXXXXXXXXXPQKIEKNDTENGKISHPNDLDEK 273
+ +SK +E+++ + E D ++ + + +D+
Sbjct: 227 EGISKFAEDED-------------------------YDDEDENYDEDSTDVKN---VDDP 258
Query: 274 PKVSDETESPIYEQLDNGLIRLHFIISKETLNELPSVNTYDIIGNFHKIYHLFDNDKETT 333
PK D S E D + L+ ISKETL++L + N +I+GN++KIYH F+ DKET
Sbjct: 259 PKNLDSISSSNIEIDDERRLVLNISISKETLSKLKTNNVEEIMGNWNKIYHSFEYDKETM 318
Query: 334 MRRLKLQENDQMLESSRK-RSHEQIE---DEEEDDSGNPSISHHK----------SAADK 379
++RLKL+E+D+M+E +K RS +E DE++ ++ N ++ S
Sbjct: 319 IKRLKLEESDKMIEKGKKKRSRSDLEAATDEQDRENTNDEPDTNQKLPTPEGSTFSDTGN 378
Query: 380 KINTKTKADIQMDLGVVNLSLRHLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASED 439
K ++ D+ ++LG+ NLSL+HLL S+Q+ KS+L ISDYELKHL+MDVR NRSKW S++
Sbjct: 379 KRPKQSNLDLTVNLGIENLSLKHLLSSIQQKKSQLGISDYELKHLIMDVRKNRSKWTSDE 438
Query: 440 KIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTF 499
+IGQEELY+ACEKVVLELRN+TEHST FLNKVSKREAPNY+QIIKK MDLNTVLKKLK+F
Sbjct: 439 RIGQEELYEACEKVVLELRNYTEHSTPFLNKVSKREAPNYHQIIKKSMDLNTVLKKLKSF 498
Query: 500 QYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVE 559
QY SK EFVDDIMLIW+NCLTYNSDP HFLR HAIAMQKKS QL+ +IP+ITIR+RA +E
Sbjct: 499 QYDSKQEFVDDIMLIWKNCLTYNSDPSHFLRGHAIAMQKKSLQLIRMIPNITIRNRADLE 558
Query: 560 KELEDIDAESNIKDDEED--AGSGRKGIQRRGVQ------KVIDDXXXXXXXNHPGGKKT 611
KE+ED++ + + + DEE+ AGSGRKG+ KV + +
Sbjct: 559 KEIEDMEKDKDYELDEEEEVAGSGRKGLNMGAHMLAKENGKVSEKDSSKTVKDEAPTNDD 618
Query: 612 RAT----DAERNQQQSTNKTVSSDKTPSTNEAEQTPEVGIVSAEGRGSKVAQSSTNNES- 666
+ T + E+ + ++ + TV+ + + NE ++ + SK SS + ++
Sbjct: 619 KLTSVIPEGEKEKDKTASSTVTVHENVNKNEIKENGKNEEQDMVEESSKTEDSSKDADAA 678
Query: 667 ---TEPAVESKAVSTVEKNQXXXXXXXXXXXXXXXXXXNAAGMMXXXXXXXXXXXXXSTW 723
TE ++ K E + ++ + S W
Sbjct: 679 KKDTEDGLQDKTAENKEAGENNEEEEDDDDEDEDEDMVDSQSYLLEKDDDRDDLEI-SVW 737
Query: 724 KTLTAKARAEICLKRSQLFNEHKINSESDALLKNPSKLKNFDQFFEEYKQQKEAEFARQK 783
KT+TAK RAEICLKR++ F K+NS+S+A LKNP ++K FDQ F EYK+QK E RQK
Sbjct: 738 KTVTAKVRAEICLKRTEYFKNGKLNSDSEAFLKNPQRMKRFDQLFLEYKEQKALESYRQK 797
Query: 784 LQEQSMMKNGFGAIMNQADSSVSNFSDTNVKSQDAESSLTKESNEITLEDSSLLTEYNIT 843
+++ S+MKNGFG ++ Q D F N S + + K+ N+I L+D+ L EY+I+
Sbjct: 798 IEQNSIMKNGFGTVLKQEDDDQLQFH--NDHSLNGNEAFEKQPNDIELDDTRFLQEYDIS 855
Query: 844 NYIPDLAYTGIGKEQLDKAEEAMVQKIMKEGKVMKSSLLNTVDKGLSPKMNTNIQLIHEI 903
N IPD+ Y G+ + LDK E+A V ++++ G +S L D GL+PKMN NI LI +I
Sbjct: 856 NAIPDIVYEGVNTKTLDKMEDASVDRMLQNGINKQSRFLANKDLGLTPKMNQNITLIQQI 915
Query: 904 RHICHKISLIRALQNPNKPKNSQQ-PLRFKEFXXXXXXXXXXX------XQLNSHDYKND 956
RHICHKISLIR LQ+P +NS+ P F QL +HDYKN+
Sbjct: 916 RHICHKISLIRMLQSPLSAQNSRSNPNAFLNNHIYNYTIIDDSLDIDPVSQLPTHDYKNN 975
Query: 957 EKLINRVLHRNVSKITMSNGFESTEPLALSMLTEITTDYLSNLIKTIKLHHETHSSNKRK 1016
+LI + +H+N+SK+ M+NGFE+ P A++MLTEI DYLSNLIKT+KLHHET+S N+
Sbjct: 976 RELIWKFMHKNISKVAMANGFETAHPSAINMLTEIAGDYLSNLIKTLKLHHETNSLNRGT 1035
Query: 1017 PAEALTMALLENGINKPDDLYSYMENEFGKKTRKLEDLKVKLSSFLKDLLRPTLQDISER 1076
E L LLENGIN+PDDL+SY+E+EFGKKT+KL+D+K KL SFL+ LLRPTLQ++SER
Sbjct: 1036 NVEMLQTTLLENGINRPDDLFSYVESEFGKKTKKLQDIKQKLESFLRALLRPTLQELSER 1095
Query: 1077 NFEDESQSFLTGDFSSEVTGEDFFGFRELGLDKEFGELANNVPLQLLTFQFNGKDTDIQV 1136
NFEDESQSF TGDF+SE+TGEDFFGFRELGL+KEFG L+++VPLQLLT QF D + +V
Sbjct: 1096 NFEDESQSFFTGDFASELTGEDFFGFRELGLEKEFGVLSSSVPLQLLTTQFQTVDGETKV 1155
Query: 1137 KAKVIQPEEFEDVIYKKLNKENVQSDSYSKLIQPLLQSAVDRCSAYYTKLARSKNADQVP 1196
+AK IQPEE + ++YKK+ K + + S+ + PLLQ +R AY K ++S D+
Sbjct: 1156 QAKKIQPEESDSIVYKKITKGMLDAGSFWNTLLPLLQKDYERSKAYIAKQSKSSANDKTS 1215
Query: 1197 -KNYESPLFPLLEDEEFPKVKGANRPRLPPTGKISTNYKKKHVSELYTLPXXXXXXXXXX 1255
+ E F LLE+++F K A + RLPPTGKIST YKKK ++ + LP
Sbjct: 1216 MTSTEDNSFALLEEDQFVSKKTATKARLPPTGKISTTYKKKPIASAFILPEEDLENDVKA 1275
Query: 1256 XXXDTAS----KPTDG----IFKSPATVD----DNGFYVEETPL---SSFSLSLP 1295
T + DG ++P +D D+ F ++T + SSFSLSLP
Sbjct: 1276 DPTTTVNAKVGAENDGDSSLFLRTPQPLDPLDMDDAF--DDTNMGSNSSFSLSLP 1328
>SPBC25H2.11c [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 979
Score = 295 bits (754), Expect = 4e-79
Identities = 262/907 (28%), Positives = 396/907 (42%), Gaps = 193/907 (21%)
Query: 346 LESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVVNLSLRHLLK 405
LE+ + +E + E+E+D+ P+ S + N + D+ +L +LL+
Sbjct: 217 LENDSENINEVKKFEDEEDTSTPNTSSFQ-------NNSSSLDLSDNLS-------YLLQ 262
Query: 406 SVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIGQEELYDACEKVVLELRNFTEHST 465
++ N+SK++ +D ++K LL DV+ N+SKWA++ +IGQEELY+A EKVVLELR++TEHS
Sbjct: 263 YLEGNRSKINATDADVKQLLSDVKKNKSKWANDQRIGQEELYEAAEKVVLELRSYTEHSL 322
Query: 466 AFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDP 525
AFL KVSKR+AP+YY +IK+PMDL T+L+ LK Y SK EFV D+MLIW NC YNS P
Sbjct: 323 AFLTKVSKRDAPDYYTVIKEPMDLGTILRNLKNLHYNSKKEFVHDLMLIWSNCFLYNSHP 382
Query: 526 KHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDEEDAGSGRKGI 585
H LR HA M+ KS +L+ LIPDI I+ R K+ +D E+ ++ DEE K
Sbjct: 383 DHPLRVHAQFMKDKSLELINLIPDIVIQSR----KDYDDSLIEAELESDEESTAETSK-- 436
Query: 586 QRRGVQKVIDDXXXXXXXNHPGGKKTRATDAERNQQQSTNKTVSS---DKTPSTNEAEQT 642
H KKT + + Q + +S + TP T + +T
Sbjct: 437 -------------------HVTSKKTSSRGGQTQQAVEVHTDANSPEENNTPVTKKEVET 477
Query: 643 PEVGIVSAEGRGSKVAQSSTNNESTEPAVESKAV---STVEKNQXXXXXXXXXXXXXXXX 699
+ VS ST P E+ + +T+EK
Sbjct: 478 SKPPAVSG---------------STPPVNEAAVIESSNTLEKEP---------------- 506
Query: 700 XXNAAGMMXXXXXXXXXXXXXSTWKTLTAKARAEICLKRSQLFNEHKINSESDALLKNPS 759
WK T R L ++ + +++ P+
Sbjct: 507 ---------------LSDVATEYWKIKTKDIRESHILNNRRILKSLQFIETELPMIRKPT 551
Query: 760 KLKNFDQFFEEYKQQKEAEFARQKLQEQSMMKNGFGAIMNQADSSVSNFSDTNVKSQDAE 819
+ F + E A + M K F IM + + + + A
Sbjct: 552 AMSAF----------IDREVAYGSIDCLPMDKGDFEPIMKLDTTPLLEYDVGSGVPMTAG 601
Query: 820 SSLTKESNE-ITLEDSSLLTEYNITNYIPDLAYTGIGKEQLDKAEEAMVQKIMKEGKVMK 878
S L ES E + D SL T +P L Y I K +Q+I K
Sbjct: 602 SVLETESEEDLYFRDYSLFEINRNTPGVPSLMYKNIAK----------MQEIRK------ 645
Query: 879 SSLLNTVDKGLSPKMNTNIQLIHEIRHICHKISLIRALQNPNKPKNSQQPLRFKEFXXXX 938
+C+KI +R LQ P QP ++
Sbjct: 646 ---------------------------LCNKIQTVRQLQLP-------QPFYYEHHKSHV 671
Query: 939 XXXXXXXXQL----NSHDYKNDEKLINRVLHRNVSKITMSNGFESTEPLALSMLTEITTD 994
L N + + + L + VL + + I GFES + AL LTEI D
Sbjct: 672 PFANNEPILLDIPQNYDNMSSFKPLAHDVLKKLCTIILFHAGFESFQMGALDALTEIAAD 731
Query: 995 YLSNLIKTIKLHHETHSSNKRKPAEALTMALLENGINKPDDLYSYMENEFGKKTRKLEDL 1054
Y++ + + + + +K + E + L E G++ +DL SY+ ++ +++ KL ++
Sbjct: 732 YMAKM-GAVMDQYLIYGKDKSQ-QEIVGQTLGELGVDDVNDLISYVYHDVERQSVKLLEI 789
Query: 1055 KVKLSSFLKDLLRPTLQDISERN-----FEDESQSFLTGDFSSEVTGEDFFGFRELGLDK 1109
+L +LLRP L SERN F +SF+TG+FS E TG+DFFG RELGLD+
Sbjct: 790 HQRLQRHFVELLRPAL---SERNDEEAIFNQNGESFVTGNFSYE-TGDDFFGLRELGLDR 845
Query: 1110 EFGELANNVPLQLLTFQFNGKDTDIQVKAKVIQPEEF-EDVIYKKLNKENVQSDSYSKLI 1168
E G + +VPL LL + + Q +A + +E+ Y + E++ ++ LI
Sbjct: 846 ELGLDSLSVPLHLLQSRLR-SNMSWQPEATIKGDQEYAPPPKYPPITAESISNE--IGLI 902
Query: 1169 QPLLQSAVDRCSAYYTKLARSKNADQVPKNYESPLFPLLEDEEFPKVKGANRPRLPPTGK 1228
Q L+ ++ E L LLEDE+ RPRLPP GK
Sbjct: 903 QGFLKKNLE----------------------EFGLDELLEDEDIRPRSKPPRPRLPPNGK 940
Query: 1229 ISTNYKK 1235
I+T K+
Sbjct: 941 ITTGRKR 947
>Hs13899209 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 1484
Score = 68.6 bits (166), Expect = 6e-11
Identities = 41/111 (36%), Positives = 63/111 (55%), Gaps = 2/111 (1%)
Query: 420 ELKHLLMDVRMNRSKWASEDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNY 479
EL HL + M K ++D ++ + A KV L++ + S FL V + APNY
Sbjct: 414 ELSHLDPNSPMREEK-KTKDLFELDDDFTAMYKV-LDVVKAHKDSWPFLEPVDESYAPNY 471
Query: 480 YQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLR 530
YQIIK PMD++++ KKL Y +K EFV+D+ ++RNC YN + + +
Sbjct: 472 YQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTK 522
>Hs7304919 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1674
Score = 66.2 bits (160), Expect = 3e-10
Identities = 37/81 (45%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Query: 442 GQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQY 501
G EL A E++V+EL + S FL VSK + P+YY IIKKP+ LN + +K+ +Y
Sbjct: 1549 GVHEL-SAFEQLVVELVRHDD-SWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEY 1606
Query: 502 KSKHEFVDDIMLIWRNCLTYN 522
K EF+DDI L++ NC YN
Sbjct: 1607 KLASEFIDDIELMFSNCFEYN 1627
>YGR252w [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 439
Score = 65.1 bits (157), Expect = 7e-10
Identities = 36/103 (34%), Positives = 61/103 (58%), Gaps = 6/103 (5%)
Query: 449 ACEKVVLELRNFTEHSTA--FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHE 506
A + ++ EL+N H+ A FL V+K E P+YY IK+PMDL+T+ KL++ +Y+ +
Sbjct: 335 AIQNILTELQN---HAAAWPFLQPVNKEEVPDYYDFIKEPMDLSTMEIKLESNKYQKMED 391
Query: 507 FVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPD 549
F+ D L++ NC YN + + + +A ++K V IP+
Sbjct: 392 FIYDARLVFNNCRMYNGENTSYYK-YANRLEKFFNNKVKEIPE 433
>At3g19040 [K] KOG0008 Transcription initiation factor TFIID subunit TAF1
Length = 1700
Score = 65.1 bits (157), Expect = 7e-10
Identities = 66/245 (26%), Positives = 107/245 (42%), Gaps = 48/245 (19%)
Query: 340 QENDQMLESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVVNLS 399
+E ++ ES R R + E EEE K+ K K +Q + + N
Sbjct: 1493 EERSEIAESRRYREVIRSEREEE----------------KRRKAKQKKKLQRGI-LENYP 1535
Query: 400 LRH---LLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKI---GQEELYDACEKV 453
R + +N + L +SD+E NR+++A + K GQ L + E +
Sbjct: 1536 PRRNDGISSESGQNINSLCVSDFE---------RNRTEYAPQPKRRKKGQVGLANILESI 1586
Query: 454 VLELR-NFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIM 512
V LR S FL V+K+EAPNY +I+K PMDL+T+ K++ +Y+ + +F D+
Sbjct: 1587 VDTLRVKEVNVSYLFLKPVTKKEAPNYLEIVKCPMDLSTIRDKVRRMEYRDRQQFRHDVW 1646
Query: 513 LIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIR-DRAQVEKELEDIDAESNI 571
I N YN ++ + PL ++ ++ DR E E +AE I
Sbjct: 1647 QIKFNAHLYNDG--------------RNLSIPPLADELLVKCDRLLDEYRDELKEAEKGI 1692
Query: 572 KDDEE 576
D +
Sbjct: 1693 VDSSD 1697
>Hs20357588_1 [K] KOG0008 Transcription initiation factor TFIID subunit TAF1
Length = 1689
Score = 63.9 bits (154), Expect = 2e-09
Identities = 48/168 (28%), Positives = 81/168 (47%), Gaps = 9/168 (5%)
Query: 408 QENKSKLDISDYELKHLLMDV-RMNRSKWASEDKIGQEELYDACEKVVLELRNFTEHSTA 466
Q ++S LD+ D +LK + R+ ++ D Q + +V + S
Sbjct: 1468 QISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP 1527
Query: 467 FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPK 526
F + V+K+ P+YY++I PMDL T+ K + +Y+S+ F+DD+ LI N + YN
Sbjct: 1528 FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPES 1587
Query: 527 HFLR-AHAI------AMQKKSQQLVPLIPDI-TIRDRAQVEKELEDID 566
+ + A I + + + L L DI T ++ A E ELE +D
Sbjct: 1588 QYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLD 1635
>Hs20357585_1 [K] KOG0008 Transcription initiation factor TFIID subunit TAF1
Length = 1710
Score = 63.9 bits (154), Expect = 2e-09
Identities = 48/168 (28%), Positives = 81/168 (47%), Gaps = 9/168 (5%)
Query: 408 QENKSKLDISDYELKHLLMDV-RMNRSKWASEDKIGQEELYDACEKVVLELRNFTEHSTA 466
Q ++S LD+ D +LK + R+ ++ D Q + +V + S
Sbjct: 1489 QISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP 1548
Query: 467 FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPK 526
F + V+K+ P+YY++I PMDL T+ K + +Y+S+ F+DD+ LI N + YN
Sbjct: 1549 FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPES 1608
Query: 527 HFLR-AHAI------AMQKKSQQLVPLIPDI-TIRDRAQVEKELEDID 566
+ + A I + + + L L DI T ++ A E ELE +D
Sbjct: 1609 QYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLD 1656
>At1g32750 [K] KOG0008 Transcription initiation factor TFIID subunit TAF1
Length = 1919
Score = 62.4 bits (150), Expect = 5e-09
Identities = 32/83 (38%), Positives = 50/83 (59%)
Query: 440 KIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTF 499
K G+ L + E++V LR E S FL VSK+EAP+Y I++ PMDL+T+ K++
Sbjct: 1797 KKGEVGLANILERIVDTLRLKEEVSRLFLKPVSKKEAPDYLDIVENPMDLSTIRDKVRKI 1856
Query: 500 QYKSKHEFVDDIMLIWRNCLTYN 522
+Y+++ +F D+ I N YN
Sbjct: 1857 EYRNREQFRHDVWQIKYNAHLYN 1879
>Hs11321642 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 1058
Score = 62.0 bits (149), Expect = 6e-09
Identities = 54/187 (28%), Positives = 85/187 (44%), Gaps = 21/187 (11%)
Query: 418 DYELKHLLMDVRMNRSKWASED-KIGQEELYDACEKVVLELRNFTEH------STAFLNK 470
D E LL+++ R K E K+ Q + + + LR+ + + F
Sbjct: 531 DLERARLLIELLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQP 590
Query: 471 VSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLR 530
VS +E P+Y IK PMD T+ K+L+ YK+ HEF +D LI NC+ YN+ F R
Sbjct: 591 VSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYR 650
Query: 531 AHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAE--SNIKDDEEDAGSGRKGIQRR 588
A A++ + Q V L Q +E++ I E S + E A + R+
Sbjct: 651 A---AVRLRDQGGVVL---------RQARREVDSIGLEEASGMHLPERPAAAPRRPFSWE 698
Query: 589 GVQKVID 595
V +++D
Sbjct: 699 DVDRLLD 705
>7298896 [K] KOG0008 Transcription initiation factor TFIID subunit TAF1
Length = 2065
Score = 62.0 bits (149), Expect = 6e-09
Identities = 31/107 (28%), Positives = 56/107 (51%), Gaps = 4/107 (3%)
Query: 438 EDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLK 497
+D++ ++D + +L S FL V+K++ +YY +IK+PMDL T+ K ++
Sbjct: 1592 DDQVALSFIFDKLHSQIKQL----PESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIE 1647
Query: 498 TFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLV 544
+Y S+ E++ DI LI NC YN + + ++ QL+
Sbjct: 1648 AHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLI 1694
Score = 53.1 bits (126), Expect = 3e-06
Identities = 36/122 (29%), Positives = 63/122 (51%), Gaps = 13/122 (10%)
Query: 456 ELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIW 515
ELR+ + S FL VS ++ P+YY+++ KPMDL T+ + ++ +Y S+ F++D+ I
Sbjct: 1485 ELRSMPDVSP-FLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIV 1543
Query: 516 RNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDE 575
N L YN A+ +A Q+ L+ A+ E +L ++ N D+
Sbjct: 1544 DNSLIYNGPQS----AYTLAAQRMFSSCFELL--------AEREDKLMRLEKAINPLLDD 1591
Query: 576 ED 577
+D
Sbjct: 1592 DD 1593
>SPAC1952.05 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 454
Score = 61.2 bits (147), Expect = 1e-08
Identities = 33/98 (33%), Positives = 54/98 (54%), Gaps = 1/98 (1%)
Query: 425 LMDVRMNRSKWASEDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIK 484
LM+V + K + + E + E++N S F+ VSK + P+YY++I+
Sbjct: 327 LMEVGWCKEMEELSKKPRPKPFFAVLEMLFTEMQNHPS-SWPFMQPVSKEDVPDYYEVIE 385
Query: 485 KPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYN 522
PMDL+T+ +L+ QY+S EF+ D I+ NC +YN
Sbjct: 386 HPMDLSTMEFRLRNNQYESVEEFIRDAKYIFDNCRSYN 423
>Hs6382076 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 832
Score = 60.8 bits (146), Expect = 1e-08
Identities = 28/97 (28%), Positives = 56/97 (56%), Gaps = 1/97 (1%)
Query: 434 KWASEDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVL 493
K S++ ++LY + ++ ++++ + + F+ V + EAP YY++I+ PMDL T+
Sbjct: 716 KEKSKEPRDPDQLYSTLKSILQQVKSH-QSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMS 774
Query: 494 KKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLR 530
++LK Y SK F+ D+ ++ NC YN+ + +
Sbjct: 775 ERLKNRYYVSKKLFMADLQRVFTNCKEYNAAESEYYK 811
>YLR399c [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 686
Score = 60.5 bits (145), Expect = 2e-08
Identities = 28/79 (35%), Positives = 46/79 (57%), Gaps = 4/79 (5%)
Query: 450 CEKVVLEL--RNFTEHSTAFLNKVS--KREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKH 505
C+ V+ EL + ++ FL V P Y+ +K+PMDL T+ KKL +QY++
Sbjct: 321 CQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTME 380
Query: 506 EFVDDIMLIWRNCLTYNSD 524
+F D+ L+++NC T+N D
Sbjct: 381 DFERDVRLVFKNCYTFNPD 399
>Hs14971411 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 1110
Score = 60.5 bits (145), Expect = 2e-08
Identities = 42/128 (32%), Positives = 64/128 (49%), Gaps = 5/128 (3%)
Query: 450 CEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLK---TFQYKSKHE 506
CE+++L L E S F V PNYY+IIKKPMDL+TV KKL+ + Y+ +
Sbjct: 966 CERLLLYLYCH-ELSIEFQEPVPA-SIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDD 1023
Query: 507 FVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDID 566
FV D+ LI++NC +N +A +L + D T + E+E +D +
Sbjct: 1024 FVADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGE 1083
Query: 567 AESNIKDD 574
+ +D
Sbjct: 1084 VTEDSDED 1091
>YDL070w [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 638
Score = 60.1 bits (144), Expect = 2e-08
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 3/100 (3%)
Query: 477 PNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAM 536
PNY+ ++K PMDL T+ L ++YK+ +FVDD+ L++ NC +N + H++
Sbjct: 357 PNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGN---EVHSMGK 413
Query: 537 QKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDEE 576
+ K + + I + + + +LE+ + S+ D+E
Sbjct: 414 KLKELFNFHWLENQDILNEIETDSDLEEDNYSSSYSSDDE 453
>Hs21071050 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1568
Score = 60.1 bits (144), Expect = 2e-08
Identities = 38/167 (22%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 464 STAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNS 523
S F+ S++E P YY++I+KP+D + ++++ +Y+S + D+ML+ N T+N
Sbjct: 1402 SEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNL 1461
Query: 524 DPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELED------------IDAESNI 571
+ + + + D + E+E ED + + N
Sbjct: 1462 EGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNK 1521
Query: 572 KDDE-EDAGSGRKGIQRRGVQKVIDDXXXXXXXNHPGGKKTRATDAE 617
KDD+ D G G+K R + V+ D + + TD E
Sbjct: 1522 KDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1568
>Hs21071048 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1586
Score = 60.1 bits (144), Expect = 2e-08
Identities = 38/167 (22%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 464 STAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNS 523
S F+ S++E P YY++I+KP+D + ++++ +Y+S + D+ML+ N T+N
Sbjct: 1420 SEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNL 1479
Query: 524 DPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELED------------IDAESNI 571
+ + + + D + E+E ED + + N
Sbjct: 1480 EGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNK 1539
Query: 572 KDDE-EDAGSGRKGIQRRGVQKVIDDXXXXXXXNHPGGKKTRATDAE 617
KDD+ D G G+K R + V+ D + + TD E
Sbjct: 1540 KDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1586
>Hs20555413 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 1205
Score = 60.1 bits (144), Expect = 2e-08
Identities = 37/121 (30%), Positives = 61/121 (49%), Gaps = 7/121 (5%)
Query: 418 DYELKHLLMDVRMNRSKWASED-KIGQEEL------YDACEKVVLELRNFTEHSTAFLNK 470
D E LL+++ R K E K+ Q + ++ + L+L + + F
Sbjct: 558 DLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEP 617
Query: 471 VSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLR 530
V+ E P+Y + I KPMD +T+ +KL++ Y++ EF +D LI NC+ YN+ F R
Sbjct: 618 VNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHR 677
Query: 531 A 531
A
Sbjct: 678 A 678
>CE19384 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 374
Score = 60.1 bits (144), Expect = 2e-08
Identities = 36/103 (34%), Positives = 58/103 (55%), Gaps = 7/103 (6%)
Query: 429 RMNRSKWASEDKIGQEELYDACEKVVLELRNF---TEHSTAFLNK----VSKREAPNYYQ 481
R ++K SED+ + L+D +K + L+ F T S F + V +Y++
Sbjct: 98 RKKKAKSESEDEAESDHLHDELKKCLSILKEFEKSTHDSFTFPFRKPVDVVLLGLTDYHE 157
Query: 482 IIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSD 524
+IKKPMD++T+ KKL +Y + EF +D L+ NCLTYN++
Sbjct: 158 VIKKPMDMSTIRKKLIGEEYDTAVEFKEDFKLMINNCLTYNNE 200
>CE24921 [R] KOG1632 Uncharacterized PHD Zn-finger protein
Length = 451
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/119 (29%), Positives = 60/119 (50%)
Query: 454 VLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIML 513
+LEL ST F N V E P+Y + IKKPMDL+T+ KK++ +Y +FV+D+
Sbjct: 299 LLELLLEHRMSTPFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQ 358
Query: 514 IWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIK 572
++ N TYN + + ++L+ + +T R + + + D S+I+
Sbjct: 359 MFENAKTYNPKGNAVFKCAETMQEVFDKKLIDVREQMTARQQMLLLATAQQQDPMSSIR 417
>CE15910 [R] KOG1632 Uncharacterized PHD Zn-finger protein
Length = 510
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/119 (29%), Positives = 60/119 (50%)
Query: 454 VLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIML 513
+LEL ST F N V E P+Y + IKKPMDL+T+ KK++ +Y +FV+D+
Sbjct: 358 LLELLLEHRMSTPFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQ 417
Query: 514 IWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIK 572
++ N TYN + + ++L+ + +T R + + + D S+I+
Sbjct: 418 MFENAKTYNPKGNAVFKCAETMQEVFDKKLIDVREQMTARQQMLLLATAQQQDPMSSIR 476
>CE15909 [R] KOG1632 Uncharacterized PHD Zn-finger protein
Length = 405
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/119 (29%), Positives = 60/119 (50%)
Query: 454 VLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIML 513
+LEL ST F N V E P+Y + IKKPMDL+T+ KK++ +Y +FV+D+
Sbjct: 253 LLELLLEHRMSTPFRNPVDLNEFPDYEKFIKKPMDLSTITKKVERTEYLYLSQFVNDVNQ 312
Query: 514 IWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIK 572
++ N TYN + + ++L+ + +T R + + + D S+I+
Sbjct: 313 MFENAKTYNPKGNAVFKCAETMQEVFDKKLIDVREQMTARQQMLLLATAQQQDPMSSIR 371
>At2g34900 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 400
Score = 59.7 bits (143), Expect = 3e-08
Identities = 24/86 (27%), Positives = 53/86 (60%)
Query: 478 NYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQ 537
+YY++I+KPMDL T+ KK+++ +Y + E D+ L+++N + YN + + ++
Sbjct: 143 DYYKVIEKPMDLGTIKKKMESSEYSNVREIYADVRLVFKNAMRYNEEKEDVYVMAESLLE 202
Query: 538 KKSQQLVPLIPDITIRDRAQVEKELE 563
K ++ + ++P + ++ QV++E E
Sbjct: 203 KFEEKWLLIMPKLVEEEKKQVDEEAE 228
>7294564 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 813
Score = 59.3 bits (142), Expect = 4e-08
Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 5/104 (4%)
Query: 429 RMNRSKWASEDKIGQEELYDACEKVVLELRNFTEHSTA--FLNKVSKREAPNYYQIIKKP 486
R RS E+ E+L + V+ +R +H+TA FL V+ E P+YY IK P
Sbjct: 692 RPARSSRPLEESTDPEKLATSFASVLQSVR---QHTTAWPFLRPVTAAEVPDYYDHIKYP 748
Query: 487 MDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLR 530
MDL T+ ++LK Y+++ F+ D+ I+ NC YNS + R
Sbjct: 749 MDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYR 792
>Hs7304923 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1972
Score = 58.5 bits (140), Expect = 7e-08
Identities = 35/119 (29%), Positives = 61/119 (50%), Gaps = 6/119 (5%)
Query: 418 DYELKHLLMDVRMNRSKWASEDKIGQEELYDA-----CEKVVLELRNFTEHSTAFLNKVS 472
D + + + + +N SK S + + + D+ C ++ E+ E + FL V+
Sbjct: 1836 DLQKRKMEENTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETH-EDAWPFLLPVN 1894
Query: 473 KREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRA 531
+ P Y ++IKKPMD +T+ +KL + QY + F D+ L++ NC T+N D RA
Sbjct: 1895 LKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRA 1953
>7290870 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 1998
Score = 58.5 bits (140), Expect = 7e-08
Identities = 41/121 (33%), Positives = 62/121 (50%), Gaps = 8/121 (6%)
Query: 443 QEELYDA---CEKVVLEL--RNFTEHSTAFLNKVSKREAP--NYYQIIKKPMDLNTVLKK 495
+E+L DA C +++ EL + + ++ F V +Y+ IIKKPMDL TV +K
Sbjct: 474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRK 533
Query: 496 LKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDR 555
+ +YKS EF D+ LI+ NC YN P H + A +Q + IPD + +
Sbjct: 534 MDNREYKSAPEFAADVRLIFTNCYKYN-PPDHDVVAMGRKLQDVFEMRYANIPDEPVANA 592
Query: 556 A 556
A
Sbjct: 593 A 593
Score = 54.3 bits (129), Expect = 1e-06
Identities = 45/169 (26%), Positives = 71/169 (41%), Gaps = 16/169 (9%)
Query: 473 KREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAH 532
K P+Y++IIK+PMD+ T+ K+L+ Y S E + D ++ NC YN P +
Sbjct: 67 KLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNK-PGEDVVVM 125
Query: 533 AIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDEEDAGSGRKGIQRRGVQK 592
A ++K Q + +P + E ELE + A+ K ++ A + K
Sbjct: 126 AQTLEKVFLQKIESMP--------KEELELEPVTAKGGKK--KQRAPATPKSSSGGAGAS 175
Query: 593 VIDDXXXXXXXNHPGGKKTRATDAERNQQQS-----TNKTVSSDKTPST 636
+ PG T+ + A + QQS T S TP T
Sbjct: 176 TGSGTSSAAVTSGPGSGSTKVSVAASSAQQSGLQGATGAGGGSSSTPGT 224
>Hs11426183 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 837
Score = 58.2 bits (139), Expect = 9e-08
Identities = 30/97 (30%), Positives = 58/97 (58%), Gaps = 6/97 (6%)
Query: 444 EELYDACEKVVLELRNFTEHSTA--FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQY 501
++LY + ++ ++++ H +A F+ V K EAP+YY++I+ P+DL T+ ++L++ Y
Sbjct: 731 DQLYTTLKNLLAQIKS---HPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYY 787
Query: 502 KSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQK 538
++ FV D+ + NC YN + R A A++K
Sbjct: 788 VTRKLFVADLQRVIANCREYNPPDSEYCRC-ASALEK 823
>Hs10835101 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 837
Score = 58.2 bits (139), Expect = 9e-08
Identities = 30/97 (30%), Positives = 58/97 (58%), Gaps = 6/97 (6%)
Query: 444 EELYDACEKVVLELRNFTEHSTA--FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQY 501
++LY + ++ ++++ H +A F+ V K EAP+YY++I+ P+DL T+ ++L++ Y
Sbjct: 731 DQLYTTLKNLLAQIKS---HPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYY 787
Query: 502 KSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQK 538
++ FV D+ + NC YN + R A A++K
Sbjct: 788 VTRKLFVADLQRVIANCREYNPPDSEYCRC-ASALEK 823
>CE05553 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1474
Score = 58.2 bits (139), Expect = 9e-08
Identities = 44/190 (23%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Query: 337 LKLQENDQMLESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVV 396
LKL + + +E +R+ E ++ + + + K +++ +
Sbjct: 1085 LKLSFDYEEMERAREEGREVVDQTPNQRRRRREVDYSSDLLSDEQFMKQVEEVEDEN--- 1141
Query: 397 NLSLRHLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIGQEELYDACEKVVLE 456
N ++ K + + LD +D + +++ + ++ +KI E+ D V+LE
Sbjct: 1142 NQAVAERKKQRKRKMAGLDENDDSMDDVVLQHKKKKTDPELAEKIN--EMLD----VILE 1195
Query: 457 LRNFTEHSTA--FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLI 514
+N A F +++E P+YYQ+I KPMD + + KK++T +Y E DD+ L+
Sbjct: 1196 YKNEDGELIADVFQTLPTRKELPDYYQVISKPMDFDRINKKIETGRYTVMEELNDDMNLL 1255
Query: 515 WRNCLTYNSD 524
N TYN +
Sbjct: 1256 VNNAQTYNEE 1265
>ECU10g1430 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 396
Score = 57.8 bits (138), Expect = 1e-07
Identities = 29/73 (39%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
Query: 463 HSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYN 522
H+ FL V E P+YY+ I KPMDL+T++ KL+ +Y FV D+ L+ NC YN
Sbjct: 299 HAWPFLRPVDPAEVPDYYKCIAKPMDLSTMVLKLRNNEYGCIEAFVADVHLMVNNCFEYN 358
Query: 523 S-DPKHFLRAHAI 534
D +++ A A+
Sbjct: 359 GRDTQYYKCAQAL 371
>7302099 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1476
Score = 57.4 bits (137), Expect = 1e-07
Identities = 32/79 (40%), Positives = 43/79 (53%), Gaps = 9/79 (11%)
Query: 446 LYDACEKVVLELRNFTEHSTA--FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKS 503
LYD E+++ +H A FL V E P+Y+QIIK PMDL + KL Y+
Sbjct: 1365 LYDLLEQIM-------KHKAAWPFLRPVLTSEVPDYHQIIKTPMDLAKIKSKLNMGAYQL 1417
Query: 504 KHEFVDDIMLIWRNCLTYN 522
E + DI L++RNC YN
Sbjct: 1418 NEELLSDIQLVFRNCDLYN 1436
>Hs11067749 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 726
Score = 57.0 bits (136), Expect = 2e-07
Identities = 49/235 (20%), Positives = 96/235 (40%), Gaps = 21/235 (8%)
Query: 450 CEKVVLEL--RNFTEHSTAFLNKVSKR--EAPNYYQIIKKPMDLNTVLKKLKTFQYKSKH 505
C+ ++ E+ + ++ F V E +Y+ IIK PMDL+TV +K+ +Y
Sbjct: 315 CDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQ 374
Query: 506 EFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIR------------ 553
F D+ L++ NC YN P H + A A +Q + +PD +
Sbjct: 375 GFAADVRLMFSNCYKYN-PPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMV 433
Query: 554 -DRAQVEKELEDIDAESNIKDDEEDAGSGRKGIQRRGVQKVIDDXXXXXXXNHPGGKKTR 612
A+ + E+ ++S D EE+ + +Q + K + + P K +
Sbjct: 434 SKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQ--LKAVHE-QLAALSQAPVNKPKK 490
Query: 613 ATDAERNQQQSTNKTVSSDKTPSTNEAEQTPEVGIVSAEGRGSKVAQSSTNNEST 667
+ + +++ +K +K E E+ +V + + + K N+ +T
Sbjct: 491 KKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTT 545
>YKR008w [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 625
Score = 56.6 bits (135), Expect = 2e-07
Identities = 47/184 (25%), Positives = 89/184 (47%), Gaps = 10/184 (5%)
Query: 389 IQMDLGVVNLSLRHLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIGQEELYD 448
++ + VV L +LK+ ++ L S+ + K L +N+ A+E KI Q L
Sbjct: 141 VKNSMQVVMLIEFEVLKAKNLKRNYLINSEVKAKLLHY---LNKLVDATEKKINQALLGA 197
Query: 449 ACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFV 508
+ K L + + S F+ V K E P YY+I+ PM L+ V + L+ QY ++F+
Sbjct: 198 SSPK---NLDDKVKLSEPFMELVDKDELPEYYEIVHSPMALSIVKQNLEIGQYSKIYDFI 254
Query: 509 DDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLV--PLIPDI-TIRDRAQVEKELEDI 565
D++L+++N +N DP + A + L+ P++ + +R ++ E +
Sbjct: 255 IDMLLVFQNAHIFN-DPSALIYKDATTLTNYFNYLIQKEFFPELQDLNERGEINLEFDKF 313
Query: 566 DAES 569
+ E+
Sbjct: 314 EFEN 317
>Hs4757866 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 1214
Score = 56.6 bits (135), Expect = 2e-07
Identities = 56/216 (25%), Positives = 93/216 (42%), Gaps = 20/216 (9%)
Query: 336 RLKLQENDQMLESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGV 395
RL +Q Q ++ R H + + +G P + ++ + N + D
Sbjct: 527 RLTIQRKSQFMQ----RLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCD---QVGRDSED 579
Query: 396 VNLSLRHLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASED-KIGQEELYDACEKVV 454
N +L+ LKS Q + D E LL+++ R K E K+ Q + +
Sbjct: 580 KNWALKEQLKSWQRLRH-----DLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFL 634
Query: 455 LELRNFTEH------STAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFV 508
+ LR E F V E P+Y IKKPMD T+ + L+ ++Y + +F
Sbjct: 635 ILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFE 694
Query: 509 DDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLV 544
+D LI NCL YN+ F RA A+ ++++ +V
Sbjct: 695 EDFNLIVSNCLKYNAKDTIFYRA-AVRLREQGGAVV 729
>Hs21071056 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1647
Score = 56.6 bits (135), Expect = 2e-07
Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 12/117 (10%)
Query: 464 STAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNS 523
S F+ S++E P YY++I+KP+D + ++++ +Y+S ++ D+ML+ +N T+N
Sbjct: 1482 SEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNL 1541
Query: 524 DPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDEEDAGS 580
+ + +I +Q + R ++EKE + ES +++ E+ GS
Sbjct: 1542 EGS-LIYEDSIVLQ-----------SVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS 1586
>CE27187 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1427
Score = 56.6 bits (135), Expect = 2e-07
Identities = 27/61 (44%), Positives = 36/61 (58%)
Query: 462 EHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTY 521
E S FL V +E P+YY +IK+PM+L T++ K+K Y E +D LI NC TY
Sbjct: 1340 ECSWPFLQPVDSKEVPDYYDVIKRPMNLRTMMNKIKQRIYNKPIEVRNDFQLILSNCETY 1399
Query: 522 N 522
N
Sbjct: 1400 N 1400
>7304241 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 1430
Score = 56.6 bits (135), Expect = 2e-07
Identities = 38/97 (39%), Positives = 48/97 (49%), Gaps = 12/97 (12%)
Query: 467 FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPK 526
F V E P+Y I+K+PMDL T+ KLK QY S + D L+ +NCL YN+
Sbjct: 636 FREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDT 695
Query: 527 HFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELE 563
F RA I M+ Q PL QV KEL+
Sbjct: 696 VFYRA-GIRMR---DQAAPLF--------VQVRKELQ 720
>Hs15295343 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 1214
Score = 56.2 bits (134), Expect = 3e-07
Identities = 54/203 (26%), Positives = 85/203 (41%), Gaps = 19/203 (9%)
Query: 336 RLKLQENDQMLESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGV 395
RL +Q Q ++ R H + + +G P + ++ + N + D
Sbjct: 527 RLTIQRKSQFMQ----RLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCD---QVGRDSED 579
Query: 396 VNLSLRHLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASED-KIGQEELYDACEKVV 454
N +L+ LKS Q + D E LL+++ R K E K+ Q + +
Sbjct: 580 KNWALKEQLKSWQRLRH-----DLERARLLVELIRKREKLKRETIKVQQIAMEMQLTPFL 634
Query: 455 LELRNFTEH------STAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFV 508
+ LR E F V E P+Y IKKPMD T+ + L+ ++Y + +F
Sbjct: 635 ILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFE 694
Query: 509 DDIMLIWRNCLTYNSDPKHFLRA 531
+D LI NCL YN+ F RA
Sbjct: 695 EDFNLIVSNCLKYNAKDTIFYRA 717
>7294205 [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1638
Score = 55.8 bits (133), Expect = 4e-07
Identities = 34/153 (22%), Positives = 72/153 (46%), Gaps = 4/153 (2%)
Query: 430 MNRSKWASEDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDL 489
+ R + + DK +++++ V+ ++ S F+ S++ P+YY+IIK+P+D+
Sbjct: 1414 LKRRRRQNLDKRSKKQMHKIMSAVIKHNQDGRTLSEPFMKLPSRQRLPDYYEIIKRPVDI 1473
Query: 490 NTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQK---KSQQLVPL 546
+L++++ +Y +E D M + +N YN + + +IA+QK ++Q +
Sbjct: 1474 KKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEAS-LIYLDSIALQKVFVGARQRITA 1532
Query: 547 IPDITIRDRAQVEKELEDIDAESNIKDDEEDAG 579
D E N +D++D G
Sbjct: 1533 AADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGG 1565
>Hs7019345 [K] KOG1828 IRF-2-binding protein CELTIX-1 contains BROMO domain
Length = 652
Score = 55.5 bits (132), Expect = 6e-07
Identities = 77/364 (21%), Positives = 149/364 (40%), Gaps = 41/364 (11%)
Query: 316 IGNFHKIY----HLFDNDKETTMRR-LKLQENDQMLESSRKRSHEQIEDEEEDDSGNPSI 370
+G HK + HL++ E ++ LK+ N+ S+ H+ E+++D
Sbjct: 1 MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKND------ 54
Query: 371 SHHKSAADKKINTKTKADIQMDLGVVNLSLRHLLKSVQENKSKLDISDYELKHLLMD--V 428
H D+K K + Q+ G R +K ++ + + + + K L V
Sbjct: 55 --HDKHKDRKRKKGKKGEKQIP-GEEKGRKRTRVKEDKKKRDRDQVENEAEKDLQCHAPV 111
Query: 429 RMN-------RSKWASEDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQ 481
R++ S A ++++ Q L +A +++ +L+ + S F V+ AP Y
Sbjct: 112 RLDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQR-KDPSAFFSFPVTDFIAPGYSM 170
Query: 482 IIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQ 541
IIK PMD +T+ +K+K Y+S E D+ L+ N + YN + + A +K
Sbjct: 171 IIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYK----AAKKLLH 226
Query: 542 QLVPLIPDITIRDRAQVEKELEDIDAESNIKDDEEDAGSGRKGIQRRGVQKVIDDXXXXX 601
+ ++ I+ Q + D+ KD + + SG G Q+ +D
Sbjct: 227 SGMKILSQERIQSLKQSIDFMADLQKTRKQKDGTDTSQSGEDG---GCWQREREDS---- 279
Query: 602 XXNHPGGKKTRATDAERNQQQSTNKTVSSDKTPSTNEAEQTPEVGIVSAEGRGSKVAQSS 661
G + A + + + +K + DK S N + ++ + E G K+ +
Sbjct: 280 -----GDAEAHAFKSPSKENKKKDKDMLEDKFKSNNLEREQEQLDRIVKES-GGKLTRRL 333
Query: 662 TNNE 665
N++
Sbjct: 334 VNSQ 337
>CE05310 [BK] KOG1827 Chromatin remodeling complex RSC subunit
RSC1/Polybromo and related proteins
Length = 1879
Score = 55.1 bits (131), Expect = 7e-07
Identities = 35/121 (28%), Positives = 57/121 (46%), Gaps = 13/121 (10%)
Query: 466 AFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDP 525
+FL +R P YY+ +K+P+D+ T+ KLK +Y + +F DD M+ +N LTY D
Sbjct: 68 SFLRLPPRRFEPEYYEQVKEPIDVTTIQHKLKIPEYLTYDQFNDDFMMFIKNNLTYYKDE 127
Query: 526 KHFLRAHAIAMQKKSQQLVPLIPDITIRDRA-----QVEKELEDIDAESNIKDDEEDAGS 580
K ++ L T + ++ E E D D E ++++EE S
Sbjct: 128 SE--------EHKDMMKIQELFEAATAKVKSGEYLDDAEDEEGDEDVEETVQEEEEPEES 179
Query: 581 G 581
G
Sbjct: 180 G 180
Score = 52.8 bits (125), Expect = 4e-06
Identities = 64/258 (24%), Positives = 107/258 (40%), Gaps = 23/258 (8%)
Query: 325 LFDNDKETTMRRLKLQENDQMLESSRKRSHEQIEDEEEDDSGNPSISHHKSA-ADKKINT 383
+F N ++ R + + LE + R++E + + S PS H S+ K +
Sbjct: 607 MFSNARDFNEPRSMIHMDAIQLEKAVLRAYEGMRNTSLGSS-IPSTPHSSSSNLMKAMKL 665
Query: 384 KTKADIQMDLGVVNLSLRHLLKSVQENKSKLDISDYE--LKHLLMDVRMNRSK-WASEDK 440
KT G N S S E ++++I ++ ++ +M + + K W
Sbjct: 666 KTPKSEVRGRGKKNFS-----GSDDEESARINIQQHQRSMEDAIMQLPIEEQKMW----- 715
Query: 441 IGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQ 500
L+ + + V E N + F+ SK E P YY +IKKPMD+ + KL+ Q
Sbjct: 716 ----RLFKSMKDVREEGTN-RPLAVNFMRLPSKEEFPAYYDVIKKPMDMMRIKHKLENRQ 770
Query: 501 YKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEK 560
Y + + V D ML+ N +N + A+++QK ++ + R QVE
Sbjct: 771 YVTLLDVVSDFMLMLSNACKFNETDSDIYK-EAVSLQKALLEMKRELDTGDDAPRVQVEL 829
Query: 561 E--LEDIDAESNIKDDEE 576
I A K DEE
Sbjct: 830 RTIFTSIFASLFSKKDEE 847
>At1g20670 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 652
Score = 55.1 bits (131), Expect = 7e-07
Identities = 55/266 (20%), Positives = 103/266 (38%), Gaps = 53/266 (19%)
Query: 467 FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNS-DP 525
+ + V E P+Y++IIK PMD +T+ KL + Y + +F D+ LI N + YNS D
Sbjct: 196 YSDPVDPEELPDYFEIIKNPMDFSTLRNKLDSGAYSTLEQFERDVFLICTNAMEYNSADT 255
Query: 526 KHFLRAHAIA----------------MQKKSQQLVPLIPDITIRDR--------AQVEKE 561
++ +A AI + +SQQ P + R R + +++
Sbjct: 256 VYYRQARAIQELAKKDFENLRQDSDDEEPQSQQQQQQQPKVARRGRPPKKHPEPSSIDRT 315
Query: 562 LEDIDAESNIKDDEEDAGSGRKGIQRRGVQKVIDDXXXXXXXNHPGGKKT---------- 611
+I A++ I D + SG +++ NH ++
Sbjct: 316 ASEISADALIPGDSSNKFSGAYNLRKAPPSYKFRQAESSVRINHNSETQSGWSVDWESEF 375
Query: 612 -------------RATDAERNQQQSTNKTVSSDKTPST-----NEAEQTPEVGIVSAEGR 653
+ + + N++ + N +S + PS +E +Q VG+ G
Sbjct: 376 PSSVVKAVNKYGMKHFNVDDNRRDTYNHLSTSTQEPSVLTTLEDELKQLIPVGLNMEYGY 435
Query: 654 GSKVAQSSTNNESTEPAVESKAVSTV 679
+A+ + N + S+ + TV
Sbjct: 436 AKSLARYAANLGPVAWKIASRRIETV 461
>Hs7304921 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1878
Score = 54.7 bits (130), Expect = 9e-07
Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 450 CEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVD 509
CE +++E+ + + + FL V+ R Y +IIK PMD +T+ ++L Y S EF
Sbjct: 1775 CEIILMEMESH-DAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA 1833
Query: 510 DIMLIWRNCLTYNSD 524
D +L++ NC T+N D
Sbjct: 1834 DALLVFDNCQTFNED 1848
>Hs14971413 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 1127
Score = 54.7 bits (130), Expect = 9e-07
Identities = 34/76 (44%), Positives = 47/76 (61%), Gaps = 5/76 (6%)
Query: 450 CEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLK---TFQYKSKHE 506
CE+++L L E S F V PNYY+IIKKPMDL+TV KKL+ + Y+ +
Sbjct: 966 CERLLLYLYCH-ELSIEFQEPVPA-SIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDD 1023
Query: 507 FVDDIMLIWRNCLTYN 522
FV D+ LI++NC +N
Sbjct: 1024 FVADVRLIFKNCERFN 1039
>At3g01770 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 601
Score = 54.7 bits (130), Expect = 9e-07
Identities = 32/83 (38%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 450 CEKVVLELRNFTEHSTAFLNKVS--KREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEF 507
CE ++ L + +H F V K P+Y+ IIK PMDL TV KL + Y S EF
Sbjct: 133 CESLLKRLMS-QQHCWLFNTPVDVVKLNIPDYFTIIKHPMDLGTVKSKLTSGTYSSPSEF 191
Query: 508 VDDIMLIWRNCLTYNSDPKHFLR 530
D+ L +RN +TYN + R
Sbjct: 192 SADVRLTFRNAMTYNPSDNNVYR 214
>Hs4826806 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 801
Score = 54.3 bits (129), Expect = 1e-06
Identities = 33/114 (28%), Positives = 57/114 (49%), Gaps = 15/114 (13%)
Query: 478 NYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQ 537
+Y+ IIK PMDL+TV +K++ Y+ EF D+ L++ NC YN P H + A A +Q
Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYN-PPDHDVVAMARKLQ 443
Query: 538 KKSQQLVPLIPDITIRD--------------RAQVEKELEDIDAESNIKDDEED 577
+ +PD + ++ E E+ +ES+ +++EE+
Sbjct: 444 DVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEE 497
>Hs4557557 [K] KOG1778 CREB binding protein/P300 and related TAZ Zn-finger
proteins
Length = 2414
Score = 54.3 bits (129), Expect = 1e-06
Identities = 47/212 (22%), Positives = 90/212 (42%), Gaps = 17/212 (8%)
Query: 342 NDQMLESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVVNLSLR 401
N Q + + ++E + E D P+ + + ++ K+ D +M+
Sbjct: 963 NSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVE-----DCKMESTETEERST 1017
Query: 402 HLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIGQ-EELYDACEKVVLELRNF 460
L ++E + + S + + + S+ KI + EEL A + L
Sbjct: 1018 ELKTEIKEEEDQPSTSA---------TQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQ 1068
Query: 461 TEHSTAFLNKVSKR--EAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNC 518
S F V + P+Y+ I+K PMDL+T+ +KL T QY+ ++VDDI L++ N
Sbjct: 1069 DPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNA 1128
Query: 519 LTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDI 550
YN + + + Q++ P++ +
Sbjct: 1129 WLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSL 1160
>Hs4502453 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 947
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 51/114 (43%), Gaps = 18/114 (15%)
Query: 478 NYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQ 537
NYY ++K PMDL T+ +K+ +YK + F D+ L++ NC YN P H + A +Q
Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYSFAADVRLMFMNCYKYN-PPDHEVVTMARMLQ 366
Query: 538 K--------------KSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDEED 577
+S L + DIT + + +E N DD ED
Sbjct: 367 DVFETHFSKIPIEPVESMPLCYIKTDIT---ETTGRENTNEASSEGNSSDDSED 417
Score = 53.5 bits (127), Expect = 2e-06
Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 5/174 (2%)
Query: 473 KREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAH 532
K + P+YY IIK PMDLNT+ K+L+ Y E ++D ++ NC YN P +
Sbjct: 60 KLKLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNK-PGDDIVLM 118
Query: 533 AIAMQKKSQQLVPLIP--DITIRDRAQVEKELEDIDAESNIKDDEEDAGSGRKGIQRRGV 590
A A++K Q + +P + + + +++K + A S+ K E+ + S + + ++
Sbjct: 119 AQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAK--EKSSPSATEKVFKQQE 176
Query: 591 QKVIDDXXXXXXXNHPGGKKTRATDAERNQQQSTNKTVSSDKTPSTNEAEQTPE 644
+ N G ++ Q K + TP+T+ + + E
Sbjct: 177 IPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSE 230
>Hs14670392 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1483
Score = 53.9 bits (128), Expect = 2e-06
Identities = 50/210 (23%), Positives = 87/210 (40%), Gaps = 26/210 (12%)
Query: 347 ESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVVNLSLR----- 401
ES+ + S + DEEE++ A ++ + + I+ V+ + R
Sbjct: 1248 ESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRL--RPRKTIRGKHSVIPPAARSGRRP 1305
Query: 402 ----HLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIGQEELYDACEKVVLEL 457
H + Q +D D E+ L++ + + + + E CE+++ ++
Sbjct: 1306 GKKPHSTRRSQPKAPPVD--DAEVDELVLQTKRSSRRQSLE--------LQKCEEILHKI 1355
Query: 458 RNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRN 517
+ S F V++ EA +YY +I PMD TV K Y+S EF+ D+ ++ N
Sbjct: 1356 VKY-RFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTN 1414
Query: 518 CLTYNSDPKHFLRAHAIAMQKKSQQLVPLI 547
YN H L M K Q LV L+
Sbjct: 1415 AEVYNCRGSHVLS----CMVKTEQCLVALL 1440
>ECU08g1640 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 370
Score = 53.9 bits (128), Expect = 2e-06
Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 9/105 (8%)
Query: 445 ELYDACEKVVLEL--RNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYK 502
E Y+ C + + +L ++ FL V P YY +IK+PMDL T+ KL+ +Y+
Sbjct: 152 EDYEFCSETLSDLVKPKHKAYNWPFLEPVDGDLVPGYYSVIKEPMDLQTMRSKLEQRRYQ 211
Query: 503 SKHEFVDDIMLIWRNCLTYNSD-------PKHFLRAHAIAMQKKS 540
S EF D+ LI NC +N+ + F +A + MQK S
Sbjct: 212 SVEEFGRDLELIVENCKKFNAPGTEVYVCGQEFEKAVKMHMQKVS 256
>At3g52280 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 369
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/177 (21%), Positives = 80/177 (44%), Gaps = 14/177 (7%)
Query: 399 SLRHLLKSVQENKSKLDIS-------DYELKHLLMDVRMNRSKWASEDKIGQEELYDACE 451
SL H LK V+E S + +S D E ++ +R + + A + + + + D
Sbjct: 37 SLEHKLKEVEEFYSSIGVSNSGSIGKDTEKGRHVVGIRKIQQEAARREAVAAKRMQDLMR 96
Query: 452 KVVLELRNFTEHSTA--FLNKVSKREAP--NYYQIIKKPMDLNTVLKKLKTFQ---YKSK 504
+ R T+H A F++ V+ +Y+++I KPMD +T+ +++ YK
Sbjct: 97 QFGTIFRQITQHKCAWPFMHPVNVEGLGLHDYFEVIDKPMDFSTIKNQMEAKDGTGYKHV 156
Query: 505 HEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKE 561
+ D+ L++ N + YN + ++K ++ +P + ++ + E+E
Sbjct: 157 MQIYADMRLVFENAMNYNEETSDVYSMAKKLLEKFEEKWAHFLPKVQEEEKIREEEE 213
>SPAC631.02 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 727
Score = 53.5 bits (127), Expect = 2e-06
Identities = 46/176 (26%), Positives = 80/176 (45%), Gaps = 16/176 (9%)
Query: 421 LKHLLMDVRMNRSKWASEDKIGQEELYDACEKVVLEL--RNFTEHSTAFLNKVSKREA-- 476
++ + D++ +R K A+E K C+ V+ EL + ++ F V+
Sbjct: 376 IRETMYDLKPHRRKDAAEMKF--------CQSVLKELLKKQHEAYAYPFYKPVNPTACGC 427
Query: 477 PNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNS--DPKHFLRAHAI 534
P+Y+++IK PMDL T+ KL +Y S F D++L+++NC +NS P H +
Sbjct: 428 PDYFKVIKHPMDLGTMQNKLNHNEYASMKAFEADMVLMFKNCYKFNSAGTPVHLMGKKLE 487
Query: 535 AMQKKSQQLVPLIPDITIRDRAQVEKELEDIDAESNIKDDE--EDAGSGRKGIQRR 588
++ +K P T + V + D E DE ED G + + R+
Sbjct: 488 SIFQKLWANKPDFDSETYMGMSSVNTDYYYGDNEVFDSGDEFLEDDGEEFEAVNRQ 543
>Hs4758056 [K] KOG1778 CREB binding protein/P300 and related TAZ Zn-finger
proteins
Length = 2442
Score = 53.5 bits (127), Expect = 2e-06
Identities = 23/74 (31%), Positives = 43/74 (58%)
Query: 477 PNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAM 536
P+Y+ I+K PMDL+T+ +KL T QY+ ++VDD+ L++ N YN + +
Sbjct: 1123 PDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLA 1182
Query: 537 QKKSQQLVPLIPDI 550
+ Q++ P++ +
Sbjct: 1183 EVFEQEIDPVMQSL 1196
>At1g76380 [R] KOG0955 PHD finger protein BR140/LIN-49
Length = 556
Score = 53.5 bits (127), Expect = 2e-06
Identities = 51/225 (22%), Positives = 97/225 (42%), Gaps = 39/225 (17%)
Query: 330 KETTMRRLKLQENDQMLESS-----------RKRSHEQIEDEEEDDSGNPSISHHKSAAD 378
++ RR +EN++ L SS R+R+ +D++E + H ++ +
Sbjct: 32 QQLLQRRNPNEENEEELRSSSRNPNFSNRSNRRRNSNSEDDDDERRDKKHRLLHGLNSHE 91
Query: 379 KKINTKTKA---DIQMDLGVVNLSLRHLLKSVQENKSKLDISDY--ELKHLLMDVRMNRS 433
+ ++ +K+ D+ D N+ K+D SD E D+ + R
Sbjct: 92 GRDSSNSKSGGGDLDSDA---------------RNRRKIDGSDNTGEKASKATDILLQRG 136
Query: 434 KWASEDKIGQEELYDACEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVL 493
+ ++L +L+ + + + E P+YY+IIK PMD T+
Sbjct: 137 SLVESTPLPDKKLLF----FILDRVQKKDTYGVYSDPADPEELPDYYEIIKNPMDFTTLR 192
Query: 494 KKLKTFQYKSKHEF---VDDIMLIWRNCLTYNS-DPKHFLRAHAI 534
KKL++ Y + +F + D+ LI N + YNS D ++ +A A+
Sbjct: 193 KKLESGAYTTLEQFEASLQDVFLICTNAMEYNSADTVYYRQARAM 237
>7295327 [BK] KOG1472 Histone acetyltransferase SAGA/ADA catalytic subunit
PCAF/GCN5 and related proteins
Length = 3080
Score = 53.5 bits (127), Expect = 2e-06
Identities = 50/185 (27%), Positives = 80/185 (43%), Gaps = 14/185 (7%)
Query: 349 SRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLG-----VVNLSLRHL 403
S +Q + +E S + S S + A + K KA + + + + R+L
Sbjct: 644 SGSAQQQQQQSQEPPSSSSSSQSGTTTTASTVRSKKQKAVLNSSGSSSTSKMADKADRNL 703
Query: 404 LKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIG------QEELYDACEKVVLEL 457
K+ KSK + + R A DK G +E L KV++ +
Sbjct: 704 SKTETTGKSKKSAAGSSASS--SSSKAERISGAYSDKSGDDFTETEEVLQIGMHKVLVYV 761
Query: 458 RNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRN 517
+N + + F++ V + AP YY II++PMDL + KL + +Y EF +D LI N
Sbjct: 762 KNHRD-AWPFVDPVEEDIAPRYYSIIRRPMDLLKMEDKLDSGEYHKFSEFRNDFRLIVNN 820
Query: 518 CLTYN 522
C YN
Sbjct: 821 CRLYN 825
>Hs17449320 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 1050
Score = 53.1 bits (126), Expect = 3e-06
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 9/130 (6%)
Query: 450 CEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKT--FQYKSKHEF 507
CE+++L L E S AF + V P+YY+IIK PMDL+T+ K+L+ Y +F
Sbjct: 908 CERLLLFLYCH-EMSLAFQDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDF 965
Query: 508 VDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDA 567
V D LI++NC +N +P + I ++ ++L+ + + + E ED
Sbjct: 966 VADFRLIFQNCAEFN-EPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESED--- 1021
Query: 568 ESNIKDDEED 577
+ DD +D
Sbjct: 1022 -NKFSDDSDD 1030
>Hs14971415 [O] KOG2177 Predicted E3 ubiquitin ligase
Length = 1015
Score = 53.1 bits (126), Expect = 3e-06
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 9/130 (6%)
Query: 450 CEKVVLELRNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKT--FQYKSKHEF 507
CE+++L L E S AF + V P+YY+IIK PMDL+T+ K+L+ Y +F
Sbjct: 873 CERLLLFLYCH-EMSLAFQDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDF 930
Query: 508 VDDIMLIWRNCLTYNSDPKHFLRAHAIAMQKKSQQLVPLIPDITIRDRAQVEKELEDIDA 567
V D LI++NC +N +P + I ++ ++L+ + + + E ED
Sbjct: 931 VADFRLIFQNCAEFN-EPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESED--- 986
Query: 568 ESNIKDDEED 577
+ DD +D
Sbjct: 987 -NKFSDDSDD 995
>Hs7657218 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 722
Score = 52.8 bits (125), Expect = 4e-06
Identities = 48/216 (22%), Positives = 88/216 (40%), Gaps = 11/216 (5%)
Query: 478 NYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQ 537
+Y IIK PMD++T+ KL+ +Y+ EF D+ L++ NC YN P H + A A +Q
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYN-PPDHEVVAMARKLQ 447
Query: 538 KKSQQLVPLIPD------ITIRDRA--QVEKELEDIDAESNIKDDEEDAGSGRKGIQRRG 589
+ +PD + + A K + + + D D+ S +
Sbjct: 448 DVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEER 507
Query: 590 VQKVIDDXXXXXXXNHPGGKKTRATDAERNQQQSTNKTVSSDKTPSTNEAEQTPEVGIVS 649
Q++ + + ++ + +++ K +K E E+ +
Sbjct: 508 AQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE 567
Query: 650 AEGRGSKVAQSSTNNES-TEPA-VESKAVSTVEKNQ 683
+ +K SS +N S EPA ++SK T E +
Sbjct: 568 PPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEE 603
>Hs19718731 [K] KOG1474 Transcription initiation factor TFIID subunit BDF1 and
related bromodomain proteins
Length = 1362
Score = 52.8 bits (125), Expect = 4e-06
Identities = 48/216 (22%), Positives = 88/216 (40%), Gaps = 11/216 (5%)
Query: 478 NYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPKHFLRAHAIAMQ 537
+Y IIK PMD++T+ KL+ +Y+ EF D+ L++ NC YN P H + A A +Q
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYN-PPDHEVVAMARKLQ 447
Query: 538 KKSQQLVPLIPD------ITIRDRA--QVEKELEDIDAESNIKDDEEDAGSGRKGIQRRG 589
+ +PD + + A K + + + D D+ S +
Sbjct: 448 DVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEER 507
Query: 590 VQKVIDDXXXXXXXNHPGGKKTRATDAERNQQQSTNKTVSSDKTPSTNEAEQTPEVGIVS 649
Q++ + + ++ + +++ K +K E E+ +
Sbjct: 508 AQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE 567
Query: 650 AEGRGSKVAQSSTNNES-TEPA-VESKAVSTVEKNQ 683
+ +K SS +N S EPA ++SK T E +
Sbjct: 568 PPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEE 603
>Hs14670390 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1483
Score = 52.8 bits (125), Expect = 4e-06
Identities = 50/210 (23%), Positives = 86/210 (40%), Gaps = 26/210 (12%)
Query: 347 ESSRKRSHEQIEDEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVVNLSLR----- 401
ES+ + S + DEEE++ A ++ + + I+ V+ + R
Sbjct: 1248 ESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRL--RPRKTIRGKHSVIPPAARSGRRP 1305
Query: 402 ----HLLKSVQENKSKLDISDYELKHLLMDVRMNRSKWASEDKIGQEELYDACEKVVLEL 457
H + Q +D D E+ L++ + + + + E CE+++ +
Sbjct: 1306 GKKPHSTRRSQPKAPPVD--DAEVDELVLQTKRSSRRQSLE--------LQKCEEILHMI 1355
Query: 458 RNFTEHSTAFLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRN 517
+ S F V++ EA +YY +I PMD TV K Y+S EF+ D+ ++ N
Sbjct: 1356 VKY-RFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTN 1414
Query: 518 CLTYNSDPKHFLRAHAIAMQKKSQQLVPLI 547
YN H L M K Q LV L+
Sbjct: 1415 AEVYNCRGSHVLS----CMVKTEQCLVALL 1440
>CE18461 [B] KOG1245 Chromatin remodeling complex WSTF-ISWI large subunit
(contains heterochromatin localization PHD and BROMO
domains)
Length = 1430
Score = 52.8 bits (125), Expect = 4e-06
Identities = 28/76 (36%), Positives = 43/76 (55%), Gaps = 1/76 (1%)
Query: 467 FLNKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSDPK 526
FL V+ + P Y II KPMDL T+ +K + Y++ +F +DI L++ NC +N D
Sbjct: 1284 FLEPVNPKLVPGYKMIISKPMDLKTIRQKNEKLIYETPEDFAEDIELMFANCRQFNIDHS 1343
Query: 527 HFLRAHAIAMQKKSQQ 542
RA I++ K Q+
Sbjct: 1344 EIGRA-GISLHKFFQK 1358
>YIL126w [BK] KOG0386 Chromatin remodeling complex SWI/SNF component SWI2 and
related ATPases (DNA/RNA helicase superfamily)
Length = 1359
Score = 51.6 bits (122), Expect = 8e-06
Identities = 52/236 (22%), Positives = 103/236 (43%), Gaps = 19/236 (8%)
Query: 302 ETLNELPSVNTYDIIGNFH---KIYHLFDNDKETTMRRLKLQENDQMLESSRKRSHEQIE 358
ETL P + +I N + + DKETT R K + S +KR+ +
Sbjct: 1106 ETLENTPEASETSLIENNSFTAAVDEETNADKETTASRSKRRS------SRKKRTISIVT 1159
Query: 359 DEEEDDSGNPSISHHKSAADKKINTKTKADIQMDLGVVNLSLRHLLKSVQENKSK-LDIS 417
E+++++ S S A + K+ + ++ L ++ NK+ L+ +
Sbjct: 1160 AEDKENTQEESTSQENGGAKVEEEVKSSSVEIINGSESKKKKPKLTVKIKLNKTTVLENN 1219
Query: 418 DYELKHLLMDVRMNRSKWASEDKIGQEE---LYDACEKVVLELRNFTEH------STAFL 468
D + + + K A++ + + ++ EK+V E+R + ++ F
Sbjct: 1220 DGKRAEEKPESKSPAKKTAAKKTKTKSKSLGIFPTVEKLVEEMREQLDEVDSHPRTSIFE 1279
Query: 469 NKVSKREAPNYYQIIKKPMDLNTVLKKLKTFQYKSKHEFVDDIMLIWRNCLTYNSD 524
SKR+ P+Y+++I+KPM ++ +LK K YK+ E + ++ N YN +
Sbjct: 1280 KLPSKRDYPDYFKVIEKPMAIDIILKNCKNGTYKTLEEVRQALQTMFENARFYNEE 1335
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.310 0.128 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,843,219
Number of Sequences: 60738
Number of extensions: 3017394
Number of successful extensions: 11526
Number of sequences better than 1.0e-05: 63
Number of HSP's better than 0.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 11369
Number of HSP's gapped (non-prelim): 157
length of query: 1300
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1182
effective length of database: 23,222,132
effective search space: 27448560024
effective search space used: 27448560024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)