ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3265 good A KOG3013 RNA processing and modification Exosomal 3'-5' exoribonuclease complex, subunit Rrp4
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3265 1131698 1130388 -437
(437 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR069c [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subun... 468 e-132
SPAC2F7.14c [A] KOG3013 Exosomal 3'-5' exoribonuclease complex s... 303 4e-82
Hs19923403 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex su... 218 1e-56
7291605 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subun... 213 3e-55
CE27533 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subun... 181 2e-45
At1g03360 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex sub... 164 2e-40
ECU10g1340 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex su... 136 5e-32
>YHR069c [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 359
Score = 468 bits (1205), Expect = e-132
Identities = 236/360 (65%), Positives = 280/360 (77%), Gaps = 8/360 (2%)
Query: 80 MSDVISVINRNEFWSNGRLXXXXXXXXXXXXXXXXHDIEMSGAHDSNGGIDHQ-DGSIVT 138
MS+VI++ RN + N +D E HD N + D IVT
Sbjct: 1 MSEVITITKRNGAFQNS----SNLSYNNTGISDDENDEEDIYMHDVNSASKSESDSQIVT 56
Query: 139 PGELITDDPIWMKGHGTYFLENKTYSSVVGTVSRVNRLLSVLPLKSRYIPETGDHIVGRI 198
PGEL+TDDPIWM+GHGTYFL+N TYSSV GTVSRVNRLLSV+PLK RY PETGDH+VGRI
Sbjct: 57 PGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETGDHVVGRI 116
Query: 199 TDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRKSETDELQMRNFLKEGDLLNAEVQSL 258
+VGN+RWKVDIG KQ+AVLMLGSVNLPGG+LRRKSE+DELQMR+FLKEGDLLNAEVQSL
Sbjct: 117 AEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLLNAEVQSL 176
Query: 259 FQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSKNHTHNLPGNVTIILGVNGFVWIRKS 318
FQDGSASLHTRSLKYGKLRNG F QVPSSLIVR+KNHTHNLPGN+T++LGVNG++W+RK+
Sbjct: 177 FQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNGYIWLRKT 236
Query: 319 SKMDLXXXXXXXXXXXXDHLPGSNNAMSV--SITRLEEESSWEIYSDKND-TVTVSVRQT 375
S+MDL G A+S+ SITRLEEESSW+IYSD+ND +++ ++RQ
Sbjct: 237 SQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPSISNNIRQA 296
Query: 376 ITRYANVIKALAHCELGITEPRIISAYEASMAYGNLGQLIESETMESLGQDVINSEKMRG 435
I RYANVIKALA CE+GIT+ RI+SAYEASM Y N+G+LIE MES+G D++ +EKMRG
Sbjct: 297 ICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESIGSDILTAEKMRG 356
>SPAC2F7.14c [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 329
Score = 303 bits (775), Expect = 4e-82
Identities = 160/315 (50%), Positives = 210/315 (65%), Gaps = 25/315 (7%)
Query: 118 EMSGAHDSNGGIDHQDGSI----VTPGELITDDPIWMKGHGTYFLENKTYSSVVGTVSRV 173
E G D ++ D SI VTPG+L+TDDP +M+GHGTYF + Y+SV G+V RV
Sbjct: 35 EQMGLVDGEDVLEEFDKSIHQNLVTPGQLVTDDPQFMRGHGTYFEDGGIYASVAGSVQRV 94
Query: 174 NRLLSVLPLKSRYIPETGDHIVGRITDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRK 233
N+L+SV PL+S+Y+PE GD I+G+I +V +RWKVDIGAKQ AVLML S+NLPGG+ RRK
Sbjct: 95 NKLISVKPLRSKYVPEIGDLIIGKIAEVQPKRWKVDIGAKQNAVLMLSSINLPGGIQRRK 154
Query: 234 SETDELQMRNFLKEGDLLNAEVQSLFQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSK 293
ETDELQMR+F +EGDLL AEVQ F DGS S+HTRSLKYGKLRNG F++VP +L+VRSK
Sbjct: 155 LETDELQMRSFFQEGDLLVAEVQQYFSDGSVSIHTRSLKYGKLRNGVFLKVPPALVVRSK 214
Query: 294 NHTHNLPGNVTIILGVNGFVWIRKSSKMDLXXXXXXXXXXXXDHLPGSNNAMSVSITRLE 353
+H + L G V IIL VNG+VW+ K ++ N SVSITRLE
Sbjct: 215 SHAYALAGGVDIILSVNGYVWVSKHNE---------------------NQHSSVSITRLE 253
Query: 354 EESSWEIYSDKNDTVTVSVRQTITRYANVIKALAHCELGITEPRIISAYEASMAYGNLGQ 413
EE+S IYS++ND + R I+R + IK LA L +T+ I + YE+S+ + NL
Sbjct: 254 EEASESIYSNENDEIDGYTRLNISRVSICIKGLASRSLPLTQASITNFYESSLVFSNLQD 313
Query: 414 LIESETMESLGQDVI 428
L + M+ + + +
Sbjct: 314 LTVPKNMDQIAMEAM 328
>Hs19923403 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 293
Score = 218 bits (556), Expect = 1e-56
Identities = 123/288 (42%), Positives = 175/288 (60%), Gaps = 33/288 (11%)
Query: 136 IVTPGELITDDPIWMKGHGTYFLENKTYSSVVGTVSRVNRLLSVLPLKSRYIPETGDHIV 195
+V PG+ IT D +M+GHGTY E K +SV G+V RVN+L+ V LK+RYI E GD +V
Sbjct: 26 LVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVV 85
Query: 196 GRITDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRKSETDELQMRNFLKEGDLLNAEV 255
GRIT+V +RWKV+ ++ +VL+L S+NLPGG LRR+S DEL MR FL+EGDL++AEV
Sbjct: 86 GRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEV 145
Query: 256 QSLFQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSKNHTHNLPGNVTIILGVNGFVWI 315
Q++F DG+ SLHTRSLKYGKL G VQV SL+ R K H H+LP ++ILG NGF+WI
Sbjct: 146 QAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWI 205
Query: 316 RKSSKMDLXXXXXXXXXXXXDHLPGSNNAMSVSITRLEEESSWEIYSDKNDTVTVSVRQT 375
+ + EEE+ I + + V+++ R+
Sbjct: 206 YPTPE------------------------------HKEEEAGGFIAN--LEPVSLADREV 233
Query: 376 ITRYANVIKALAHCELGITEPRIISAYEASMAYGNLGQLIESETMESL 423
I+R N I +L + + + I+ YEAS+ + + +++ E ME +
Sbjct: 234 ISRLRNCIISLVTQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEI 280
>7291605 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 298
Score = 213 bits (543), Expect = 3e-55
Identities = 119/292 (40%), Positives = 173/292 (58%), Gaps = 35/292 (11%)
Query: 136 IVTPGELITDDPIWMKGHGTYFLENKTYSSVVGTVSRVNRLLSVLPLKSRYIPETGDHIV 195
+ TPGE++ + +M+GHGT+ + SSV G + +VN+L+SV PLKSRY+ E GD +V
Sbjct: 29 VYTPGEVLMPEAGFMRGHGTFVEDENIKSSVAGVIQKVNKLISVRPLKSRYVGEIGDVVV 88
Query: 196 GRITDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRKSETDELQMRNFLKEGDLLNAEV 255
R+++V +RW+VD ++ ++L+L SVNLPGG LRR+S DE MR +L EGDL++AEV
Sbjct: 89 ARVSEVQQKRWRVDTNSRLDSILLLSSVNLPGGELRRRSAEDEQMMRRYLDEGDLISAEV 148
Query: 256 QSLFQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSKNHTHNLPGNVTIILGVNGFVWI 315
Q++F++GS SL+TRSLKYGKL G V+V +L+ R K H HNLP ++ILG NG++WI
Sbjct: 149 QNIFEEGSLSLYTRSLKYGKLSQGILVKVFPALVKRRKMHFHNLPCGASVILGNNGYIWI 208
Query: 316 RKSSKMDLXXXXXXXXXXXXDHLPGSNNAMSVSITRLEEESSWE--IYSDKNDTVTVSVR 373
S T+ +EE E + N+ V + R
Sbjct: 209 --------------------------------SPTKGQEEEGGEGGFAQNLNEHVPRADR 236
Query: 374 QTITRYANVIKALAHCELGITEPRIISAYEASMAYGNLGQLIESETMESLGQ 425
+ I R N I ALA C+L I + I AYE S+ Y +L++ + +GQ
Sbjct: 237 EVIARLRNSILALAKCKLMIYDTSIQYAYEESLRY-EAHELLQQNAIYDIGQ 287
>CE27533 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 303
Score = 181 bits (458), Expect = 2e-45
Identities = 112/295 (37%), Positives = 156/295 (51%), Gaps = 33/295 (11%)
Query: 130 DHQDGSIVTPGELITDDPI-WMKGHGTYFLENKTYSSVVGTVSRVNRLLSVLPLKSRYIP 188
D + IV PG + D P +M+GHGTY + + SS+ G V ++NRLL V +K RY
Sbjct: 25 DIDETKIVIPGHSVCDAPQQFMRGHGTYVRDGEIVSSLSGVVQQLNRLLMVKTIKQRYAG 84
Query: 189 ETGDHIVGRITDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRKSETDELQMRNFLKEG 248
E GD +V R+ +V +RWK D+ ++ +A L LGSV LPGG RRK DE +M FLK G
Sbjct: 85 EVGDVVVARVVEVQAKRWKCDVASRLHANLPLGSVLLPGGDFRRKDVEDEEKMSEFLKNG 144
Query: 249 DLLNAEVQSLFQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSKNHTHNLPGNVTIILG 308
+L+ AEVQ + DG+ LHTR+ KYGKL+ G ++VP LI +SK H H LP + +I+G
Sbjct: 145 ELICAEVQQVQHDGTLMLHTRNNKYGKLQQGILIKVPPHLIKKSKKHFHTLPYGMAVIIG 204
Query: 309 VNGFVWIRKSSKMDLXXXXXXXXXXXXDHLPGSNNAMSVSITRLEEESSWEIYSDKNDTV 368
NG VW+ S LP T LEE+ S + + V
Sbjct: 205 CNGSVWVTPS-------------------LPE---------TTLEEDGS---HVHEFQIV 233
Query: 369 TVSVRQTITRYANVIKALAHCELGITEPRIISAYEASMAYGNLGQLIESETMESL 423
VR T+ R A ++ L + I + + YE S Y + +L E +T L
Sbjct: 234 PPDVRVTMVRIAACVRLLRDYSISIYLNSLTTCYEMSQPY-EIKELAEQDTSSRL 287
>At1g03360 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 322
Score = 164 bits (416), Expect = 2e-40
Identities = 90/260 (34%), Positives = 143/260 (54%), Gaps = 21/260 (8%)
Query: 136 IVTPGELITDDPIWMKGHGTYFLENKTYSSVVGTVSRVNRLLSVLPLKSRYIPETGDHIV 195
IVT + D ++KGHGT ++ + ++V G V RV++L+ V L++RY PE GD +V
Sbjct: 39 IVTDSIPVNHDDAFLKGHGTSEVDGELLATVCGVVERVDKLVYVRTLRARYKPEVGDIVV 98
Query: 196 GRITDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRKSETDELQMRNFLKEGDLLNAEV 255
GR+ +V +RW+V++ Q VLML S+N+P G+ RR++ DEL MRN E D++ AEV
Sbjct: 99 GRVIEVAQKRWRVELNFNQDGVLMLSSMNMPDGIQRRRTSVDELNMRNIFVEHDVVCAEV 158
Query: 256 QSLFQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSKNHTHNLPG-NVTIILGVNGFVW 314
++ DGS L RS KYGKL G ++V L+ RSK+H H + + +I+G NGF+W
Sbjct: 159 RNFQHDGSLQLQARSQKYGKLEKGQLLKVDPYLVKRSKHHFHYVESLGIDLIIGCNGFIW 218
Query: 315 IRKSSKMDLXXXXXXXXXXXXDHLPGSNNAMSVSITRLEEESSWEIYSDKNDTVTVSVRQ 374
+ + ++ + M++ + EE S + + + RQ
Sbjct: 219 VGEHVEV--------------------RDPMAIDDQKDEEMISSSSTGKEQSHIPLETRQ 258
Query: 375 TITRYANVIKALAHCELGIT 394
TI R N I+ L++ +T
Sbjct: 259 TICRIGNAIRVLSNLGFTVT 278
>ECU10g1340 [A] KOG3013 Exosomal 3'-5' exoribonuclease complex subunit Rrp4
Length = 223
Score = 136 bits (343), Expect = 5e-32
Identities = 72/187 (38%), Positives = 117/187 (62%), Gaps = 2/187 (1%)
Query: 135 SIVTPGELITDDPIWMKGHGTYFLENKTYSSVVGTVSRVNRLLSVLPL-KSRYIPETGDH 193
+++ PGE + + +++GHGT + S+ G N+L++V P+ +Y PE GD
Sbjct: 3 TLLLPGEDVLESEGYIRGHGTQLRGSCIASTYFGRPRITNKLVTVDPMFPLKYSPEVGDV 62
Query: 194 IVGRITDVGNRRWKVDIGAKQYAVLMLGSVNLPGGVLRRKSETDELQMRNFLKEGDLLNA 253
+VGR+ + N++WK+++ +K L L ++NLPG V RRK E+DE+ MR+F + DL+ +
Sbjct: 63 VVGRVIGIHNKKWKMELNSKADVYLGLSAINLPGTVQRRKQESDEISMRDFFEIDDLVVS 122
Query: 254 EVQSLFQDGSASLHTRSLKYGKLRNGTFVQVPSSLIVRSKNHTHNLPGNVTIILGVNGFV 313
EVQ + ++G A+LHTRS KYGKL G V VP L+ K + G+V +I+G NG++
Sbjct: 123 EVQKVGRNGVAALHTRSDKYGKLGPGLLVFVPHFLLEPLKTRFLS-NGSVEVIVGCNGYI 181
Query: 314 WIRKSSK 320
W+ + K
Sbjct: 182 WVGRGCK 188
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,773,988
Number of Sequences: 60738
Number of extensions: 924886
Number of successful extensions: 2188
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2173
Number of HSP's gapped (non-prelim): 8
length of query: 437
length of database: 30,389,216
effective HSP length: 109
effective length of query: 328
effective length of database: 23,768,774
effective search space: 7796157872
effective search space used: 7796157872
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)