ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3352 good TZ KOG1703 Cytoskeleton Adaptor protein Enigma and related PDZ-LIM proteins
r_klactV3352 good TZ KOG1703 Signal transduction mechanisms Adaptor protein Enigma and related PDZ-LIM proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3352 1164599 1162725 -625
(625 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKR090w [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM ... 236 6e-62
Hs7662330 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limat... 71 6e-12
Hs4506345 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LI... 66 1e-10
Hs5453714 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LI... 65 2e-10
CE28335 [K] KOG4577 Transcription factor LIM3 contains LIM and H... 65 2e-10
7290973 [R] KOG0490 Transcription factor contains HOX domain 65 2e-10
Hs4758670 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LI... 62 2e-09
7299033 [TZ] KOG2272 Focal adhesion protein PINCH-1 contains LIM... 62 2e-09
Hs22044051 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Lima... 62 3e-09
HsM5921986 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Lima... 61 4e-09
HsM4504999 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Lima... 61 4e-09
Hs21284385 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Lima... 61 4e-09
Hs21284383 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Lima... 61 4e-09
Hs21361591 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-L... 59 2e-08
CE04392 [TZ] KOG2272 Focal adhesion protein PINCH-1 contains LIM... 59 2e-08
CE01828 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM ... 58 4e-08
Hs14755347 [R] KOG0490 Transcription factor contains HOX domain 58 5e-08
CE15150 [R] KOG0490 Transcription factor contains HOX domain 57 6e-08
Hs7657303 [K] KOG4577 Transcription factor LIM3 contains LIM and... 57 1e-07
Hs22055163 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-L... 57 1e-07
7299231 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin... 56 1e-07
7298500 [R] KOG0490 Transcription factor contains HOX domain 56 1e-07
Hs11641283 [R] KOG0490 Transcription factor contains HOX domain 56 2e-07
7298537 [K] KOG4577 Transcription factor LIM3 contains LIM and H... 55 4e-07
Hs4504737 [R] KOG0490 Transcription factor contains HOX domain 54 5e-07
Hs15375314 [K] KOG4577 Transcription factor LIM3 contains LIM an... 54 5e-07
7291703 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM ... 54 7e-07
HsM4503721 [TZR] KOG1704 FOG: LIM domain 54 9e-07
Hs21361122 [TZR] KOG1704 FOG: LIM domain 54 9e-07
SPBC4F6.12 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-L... 53 1e-06
HsM7706250 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-L... 53 1e-06
CE27107 [R] KOG0490 Transcription factor contains HOX domain 52 2e-06
CE23977 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM ... 52 3e-06
CE17366 [R] KOG0490 Transcription factor contains HOX domain 52 3e-06
CE03650 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM ... 52 3e-06
Hs11496885 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-L... 51 6e-06
Hs20539165 [T] KOG1701 Focal adhesion adaptor protein Paxillin a... 50 8e-06
>YKR090w [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 706
Score = 236 bits (603), Expect = 6e-62
Identities = 170/528 (32%), Positives = 235/528 (44%), Gaps = 116/528 (21%)
Query: 180 QSNSSSTYNTPQMGDSGEQFPPGIDPVEQSFMQLTEN---SSVKRDSQDDGDNLRDS--- 233
Q+ + +N Q + + P+E+SFM LT+N S V +Q D + D
Sbjct: 169 QAADNFPFNFEQEDAGNTEREQDLSPIERSFMMLTQNDTASVVNSMNQTDNRGVLDQKLG 228
Query: 234 -----------YHSSVDDADVSNHISVNFAPNSALSKALLHDEPEPALIPNILVSETSDV 282
Y S D ++ S+NF P+ L L E EP L + ++ +
Sbjct: 229 KEQQKEESSIEYESEGQQEDENDIESLNFEPDPKLQMNL---ENEP-LQDDFPEAKQEEK 284
Query: 283 HDLPPVPVVSIQAXXXXXXXXXXXXXXXXXINPLYPNNDLKQIEQIPSVVVEPEIVSKSA 342
+ P +P +++ + +YP+++ +E P + S S
Sbjct: 285 NTEPKIPEINVTRESNTPSLTMNALD-----SKIYPDDNFSGLESSKEQK-SPGVSSSST 338
Query: 343 EPELNSPDG------KLTA--------------MEKLIAELDTVTLTRNKGLTPDQELSL 382
+ E S DG +T+ +E+LIA+LD V+L+RN L +
Sbjct: 339 KVEDLSLDGLNEKRLSITSSENVETPYTATNLQVEQLIAQLDDVSLSRNAKLDMNGNCLN 398
Query: 383 ELGTKQTHLKKSSAYLSHYEPQMINIPEMQRP----------------------DEEGTL 420
+ K + KKSSAYLS Y P M +IP Q+ DE+
Sbjct: 399 AVDRKASRFKKSSAYLSGY-PSM-DIPVTQQTSIVQNSNTNLSRQTILVDKGDVDEDAPS 456
Query: 421 MSLQSNSTPTFYNFHKESHEPIQTP----PEKIRDSLPRQQELH---------------- 460
S + TP FY F + + E E R LP + L
Sbjct: 457 ESTTNGGTPIFYKFKQSNVEYSNNEGMGSQETFRTKLPTIEALQLQHKRNITDLREEIDN 516
Query: 461 ------------------------EQTPMEV-YPPGHGPCRNCHKEVVGKGIYSKHENEL 495
E P+E YPPG GPCR C EV GK ++SK ENEL
Sbjct: 517 SKSNDSHVLPNGGTTRYSSDADYKETEPIEFKYPPGEGPCRACGLEVTGKRMFSKKENEL 576
Query: 496 SGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVCNGFIEGECLEND 555
SGQWHR CFKCI C F+K VPCYIL D+PYCQ H+HE+N+SICKVC+ FIEGECLEND
Sbjct: 577 SGQWHRECFKCIECGIKFNKHVPCYILGDEPYCQKHYHEENHSICKVCSNFIEGECLEND 636
Query: 556 KNERFHPSCLKCYICAKVIGQDYYVFNHEHTICNRHDINTLKETGVSS 603
K ERFH CL C++C I DYY+FN E +C HD+ L + G+ +
Sbjct: 637 KVERFHVDCLNCFLCKTAITNDYYIFNGEIPLCGNHDMEALLKEGIDN 684
>Hs7662330 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 683
Score = 70.9 bits (172), Expect = 6e-12
Identities = 43/140 (30%), Positives = 69/140 (48%), Gaps = 17/140 (12%)
Query: 457 QELHEQTPMEVYPPGHGPCRNCHKEVV-GKGIYSKHENELSGQWHRGCFKCITCSKPFSK 515
Q + P+++ P H C C +E+ G+ + + L QWH CFKC TCS +
Sbjct: 135 QSMASSKPIKIRGPSH--CAGCKEEIKHGQSLLA-----LDKQWHVSCFKCQTCSVILTG 187
Query: 516 RVPCYI-LDDQPYCQLHFHEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVI 574
YI D PYC+ +H + C+ C+ +I G LE + +HP+C +C C ++
Sbjct: 188 E---YISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAG-GKHYHPTCARCVRCHQMF 243
Query: 575 --GQDYYVFNHE--HTICNR 590
G++ Y+ E H IC +
Sbjct: 244 TEGEEMYLTGSEVWHPICKQ 263
>Hs4506345 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 557
Score = 66.2 bits (160), Expect = 1e-10
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 10/123 (8%)
Query: 466 EVYPPGHGPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQ 525
+++ P G C + I + + L+ WH CF C C PF + D Q
Sbjct: 436 DMFAPKCGGC--------ARAILENYISALNTLWHPECFVCRECFTPFVNG-SFFEHDGQ 486
Query: 526 PYCQLHFHEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEH 585
PYC++H+HE+ S+C C I G C+ ++FHP C C K + + + ++
Sbjct: 487 PYCEVHYHERRGSLCSGCQKPITGRCI-TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDK 545
Query: 586 TIC 588
C
Sbjct: 546 PYC 548
>Hs5453714 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 596
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C ++++G+ I N L WH CF C+ C KP V ++ D +PYC+ ++
Sbjct: 479 CGRCQRKILGEVI-----NALKQTWHVSCFVCVACGKPIRNNV-FHLEDGEPYCETDYYA 532
Query: 535 KNNSICKVCNGFIE-GECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTICNRH 591
+IC C IE G+ +H +C C +C + + + + +C +H
Sbjct: 533 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 590
>CE28335 [K] KOG4577 Transcription factor LIM3 contains LIM and HOX domains
Length = 351
Score = 65.5 bits (158), Expect = 2e-10
Identities = 30/127 (23%), Positives = 62/127 (48%), Gaps = 6/127 (4%)
Query: 485 KGIYSKHENELSGQ-WHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVC 543
K I + ++++G+ +H C +C TC C++ +D YC+ HF++K + C C
Sbjct: 53 KKIRDRFVSKVNGRCYHSSCLRCSTCKDELG--ATCFLREDSMYCRAHFYKKFGTKCSSC 110
Query: 544 N-GFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYVFNHEHTICNRHDINTLKETG 600
N G + + N +H C +C+IC + + G+++Y+ + + + D ++
Sbjct: 111 NEGIVPDHVVRKASNHVYHVECFQCFICKRSLETGEEFYLIADDARLVCKDDYEQARDKH 170
Query: 601 VSSLPAD 607
+ L D
Sbjct: 171 CNELEGD 177
>7290973 [R] KOG0490 Transcription factor contains HOX domain
Length = 505
Score = 65.5 bits (158), Expect = 2e-10
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 10/124 (8%)
Query: 469 PPGHG-PCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPY 527
P G G PC C+K ++ K + N L WH C +C C +P + + C+ + + Y
Sbjct: 20 PVGVGDPCAGCNKPILDKFLL----NVLERAWHASCVRCCECLQPLTDK--CFSRESKLY 73
Query: 528 CQLHFHEKNNSICKVCN-GFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYVFNHE 584
C+ F + + C C G + + +++ FH +C C IC K + G+ YV +
Sbjct: 74 CRNDFFRRYGTKCSGCGQGIAPSDLVRKPRDKVFHLNCFTCCICRKQLSTGEQLYVLDDN 133
Query: 585 HTIC 588
IC
Sbjct: 134 KFIC 137
>Hs4758670 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 386
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 13/117 (11%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQ---WHRGCFKCITCSKPFSKRVPCYILDDQPYCQLH 531
C C++ V+ EN LS WH CF C C FS + LD +P+C+LH
Sbjct: 270 CGGCNRPVL--------ENYLSAMDTVWHPECFVCGDCFTSFSTG-SFFELDGRPFCELH 320
Query: 532 FHEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTIC 588
+H + ++C C I G C+ + +FHP C C + + + ++ T C
Sbjct: 321 YHHRRGTLCHGCGQPITGRCI-SAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYC 376
>7299033 [TZ] KOG2272 Focal adhesion protein PINCH-1 contains LIM domains
Length = 335
Score = 62.4 bits (150), Expect = 2e-09
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 499 WHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVCNGFIEGECLENDKNE 558
WH CF C C +PF + Y + + YC+ FH C C F+ G ++ +
Sbjct: 29 WHTQCFVCAQCFRPFQDGI-FYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKA-MSA 86
Query: 559 RFHPSCLKCYICAKVIGQDYYVFNHEHTICNRHDIN 594
+HP C +C +CAK + ++ N +C H+ N
Sbjct: 87 SWHPQCFRCQLCAKELADCGFIKNQNRALC--HECN 120
>Hs22044051 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 443
Score = 61.6 bits (148), Expect = 3e-09
Identities = 41/118 (34%), Positives = 55/118 (45%), Gaps = 15/118 (12%)
Query: 495 LSGQWHRGCFKCITCSKPFSKRVPCYI-LDDQPYCQLHFHEKNNSICKVCNGFIEGECLE 553
L WH GCFKC +C K + YI D PYC+ +H K C C +I G LE
Sbjct: 40 LDKHWHLGCFKCKSCGKLLNAE---YISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLE 96
Query: 554 NDKNERFHPSCLKCYICAKVI--GQDYYVFNHE--HTICNR----HDINTLKETGVSS 603
+ + +HPSC C C ++ G++ Y+ H C + D N KET SS
Sbjct: 97 AGE-KHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTEDRN--KETRTSS 151
>HsM5921986 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 626
Score = 61.2 bits (147), Expect = 4e-09
Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 13/110 (11%)
Query: 475 CRNCHKEVV-GKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYI-LDDQPYCQLHF 532
C C +++ G+ + + L QWH GCFKC +C K + YI D PYC+ +
Sbjct: 74 CAGCGRDIKNGQALLA-----LDKQWHLGCFKCKSCGKVLTGE---YISKDGAPYCEKDY 125
Query: 533 HEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYV 580
C+ C+ FI G+ LE ++ +HPSC +C C ++ G++ Y+
Sbjct: 126 QGLFGVKCEACHQFITGKVLEAG-DKHYHPSCARCSRCNQMFTEGEEMYL 174
>HsM4504999 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 778
Score = 61.2 bits (147), Expect = 4e-09
Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 13/110 (11%)
Query: 475 CRNCHKEVV-GKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYI-LDDQPYCQLHF 532
C C +++ G+ + + L QWH GCFKC +C K + YI D PYC+ +
Sbjct: 226 CAGCGRDIKNGQALLA-----LDKQWHLGCFKCKSCGKVLTGE---YISKDGAPYCEKDY 277
Query: 533 HEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYV 580
C+ C+ FI G+ LE ++ +HPSC +C C ++ G++ Y+
Sbjct: 278 QGLFGVKCEACHQFITGKVLEAG-DKHYHPSCARCSRCNQMFTEGEEMYL 326
>Hs21284385 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 626
Score = 61.2 bits (147), Expect = 4e-09
Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 13/110 (11%)
Query: 475 CRNCHKEVV-GKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYI-LDDQPYCQLHF 532
C C +++ G+ + + L QWH GCFKC +C K + YI D PYC+ +
Sbjct: 74 CAGCGRDIKNGQALLA-----LDKQWHLGCFKCKSCGKVLTGE---YISKDGAPYCEKDY 125
Query: 533 HEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYV 580
C+ C+ FI G+ LE ++ +HPSC +C C ++ G++ Y+
Sbjct: 126 QGLFGVKCEACHQFITGKVLEAG-DKHYHPSCARCSRCNQMFTEGEEMYL 174
>Hs21284383 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 778
Score = 61.2 bits (147), Expect = 4e-09
Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 13/110 (11%)
Query: 475 CRNCHKEVV-GKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDD-QPYCQLHF 532
C C +++ G+ + + L QWH GCFKC +C K + YI D PYC+ +
Sbjct: 226 CAGCGRDIKNGQALLA-----LDKQWHLGCFKCKSCGKVLTGE---YISKDGAPYCEKDY 277
Query: 533 HEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYV 580
C+ C+ FI G+ LE ++ +HPSC +C C ++ G++ Y+
Sbjct: 278 QGLFGVKCEACHQFITGKVLEAG-DKHYHPSCARCSRCNQMFTEGEEMYL 326
>Hs21361591 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 444
Score = 58.9 bits (141), Expect = 2e-08
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C+ C ++ I + LS WH CF C C PFS + + +P C+ HFH
Sbjct: 329 CQGCQGPILDNYI-----SALSALWHPDCFVCRECFAPFSGG-SFFEHEGRPLCENHFHA 382
Query: 535 KNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAK 572
+ S+C C + G C+ + RFHP C C +
Sbjct: 383 RRGSLCATCGLPVTGRCV-SALGRRFHPDHFTCTFCLR 419
>CE04392 [TZ] KOG2272 Focal adhesion protein PINCH-1 contains LIM domains
Length = 348
Score = 58.9 bits (141), Expect = 2e-08
Identities = 31/94 (32%), Positives = 45/94 (46%), Gaps = 3/94 (3%)
Query: 496 SGQ-WHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVCNGFIEGECLEN 554
SGQ WH CF C C +PF + + + + YC+ FH + C CN FI G ++
Sbjct: 38 SGQVWHSECFVCAQCFEPFPDGI-YFEYEGRKYCEHDFHVLFSPCCGKCNEFIVGRVIK- 95
Query: 555 DKNERFHPSCLKCYICAKVIGQDYYVFNHEHTIC 588
N +HP C C IC K + ++ N +C
Sbjct: 96 AMNASWHPGCFCCEICNKQLADVGFLRNAGRALC 129
>CE01828 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 256
Score = 58.2 bits (139), Expect = 4e-08
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 7/96 (7%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C + + I + L WH CF C C F+ + + P C+ H+HE
Sbjct: 137 CNGCSQPITSNFITA-----LGTHWHPDCFVCQHCGVSFNG-ASFFEHNGAPLCERHYHE 190
Query: 535 KNNSICKVCNGFIEGECLENDKNERFHPSCLKCYIC 570
SIC C G I G C+ +FHP +C C
Sbjct: 191 SRGSICSQCRGAINGRCVA-AMGRKFHPEHFRCSYC 225
Score = 55.8 bits (133), Expect = 2e-07
Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 7/118 (5%)
Query: 473 GPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHF 532
G C C K ++G+ + + L WH + C C +R P + + + +C+ +
Sbjct: 17 GDCAACGKPIIGQVVIA-----LGKMWHPEHYTCCECGAELGQR-PFFERNGRAFCEEDY 70
Query: 533 HEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTICNR 590
H + + C+ C+ I C+ + N+ FH C C C + G+D + + T C R
Sbjct: 71 HNQFSPKCQGCHRAITDRCV-SVMNKNFHIECFTCAECNQPFGEDGFHEKNGQTYCKR 127
>Hs14755347 [R] KOG0490 Transcription factor contains HOX domain
Length = 359
Score = 57.8 bits (138), Expect = 5e-08
Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 470 PGHGPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQ 529
PG C C ++ + I + +WH C KC CS+ + C++ D + YC+
Sbjct: 22 PGTAMCVGCGSQIHDQFILRVSPDL---EWHAACLKCAECSQYLDETCTCFVRDGKTYCK 78
Query: 530 LHFHEKNNSICKVCN-GFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYVFNHEHT 586
+ C C GF + + ++ +H C +C +C++ + G ++ + EH
Sbjct: 79 RDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSL--REHE 136
Query: 587 ICNRHDINTLKETGVSSLP 605
+ R D L E + P
Sbjct: 137 LLCRADHGLLLERAAAGSP 155
>CE15150 [R] KOG0490 Transcription factor contains HOX domain
Length = 405
Score = 57.4 bits (137), Expect = 6e-08
Identities = 31/128 (24%), Positives = 59/128 (45%), Gaps = 10/128 (7%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C + ++ + +++ L WH+ C +C C P S + C+ D C+ F
Sbjct: 68 CAACAQPILDRYVFTV----LGKCWHQSCLRCCDCRAPMS--MTCFSRDGLILCKTDFSR 121
Query: 535 KNNSICKVCNGFIEGECL-ENDKNERFHPSCLKCYICAKVI--GQDYYVFNHEHTICNRH 591
+ + C C+G +E E L +++ FH C +C +C +++ G Y+ +C +
Sbjct: 122 RYSQRCAGCDGKLEKEDLVRRARDKVFHIRCFQCSVCQRLLDTGDQLYIMEGNRFVC-QS 180
Query: 592 DINTLKET 599
D T +T
Sbjct: 181 DFQTATKT 188
>Hs7657303 [K] KOG4577 Transcription factor LIM3 contains LIM and HOX domains
Length = 402
Score = 56.6 bits (135), Expect = 1e-07
Identities = 33/149 (22%), Positives = 63/149 (42%), Gaps = 19/149 (12%)
Query: 453 LPRQQELHEQTPMEVYPPGHGPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKP 512
L R+ +L + P+ C C + ++ + I L WH C KC C P
Sbjct: 23 LARRADLRREIPL---------CAGCDQHILDRFILKA----LDRHWHSKCLKCSDCHTP 69
Query: 513 FSKRVPCYILDDQPYCQLHFHEKNNSICKVCN-GFIEGECLENDKNERFHPSCLKCYICA 571
++R C+ + YC+ F ++ + C C G + + ++ +H C C +C
Sbjct: 70 LAER--CFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCK 127
Query: 572 KVI--GQDYYVFNHEHTICNRHDINTLKE 598
+ + G ++Y+ +C + D T K+
Sbjct: 128 RQLATGDEFYLMEDSRLVC-KADYETAKQ 155
>Hs22055163 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 727
Score = 56.6 bits (135), Expect = 1e-07
Identities = 29/119 (24%), Positives = 57/119 (47%), Gaps = 9/119 (7%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C+ +++G+ +++ + WH CF C C KPF + ++ D +PYC+ +
Sbjct: 610 CAKCNTKIMGEVMHALRQT-----WHTTCFVCAACKKPFGNSL-FHMEDGEPYCEKDYIN 663
Query: 535 KNNSICKVCNGFIE-GECLENDKNERFHPSCLKCYIC-AKVIGQDYYVFNHEHTICNRH 591
++ C C+ +E G+ +H +C C +C + GQ +Y + +C +H
Sbjct: 664 LFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFY-SKKDRPLCKKH 721
>7299231 [TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved
in axon guidance
Length = 765
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/82 (32%), Positives = 38/82 (45%), Gaps = 4/82 (4%)
Query: 495 LSGQWHRGCFKCITCSKPFSKRVPCYILDDQ-PYCQLHFHEKNNSICKVCNGFIEGECLE 553
L QWH CF+C C + Y+ D PYC+ + + C C+ FI G+ L+
Sbjct: 208 LDRQWHVSCFRCKACQAVLNGE---YMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQ 264
Query: 554 NDKNERFHPSCLKCYICAKVIG 575
N FHP+C +C C G
Sbjct: 265 AGDNHHFHPTCARCTKCGDPFG 286
>7298500 [R] KOG0490 Transcription factor contains HOX domain
Length = 534
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 2/109 (1%)
Query: 498 QWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVC-NGFIEGECLENDK 556
+WH C KC C + + C++ D + YC+ + + C C N F + + + K
Sbjct: 74 EWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAK 133
Query: 557 NERFHPSCLKCYICAK-VIGQDYYVFNHEHTICNRHDINTLKETGVSSL 604
+ FH C +C CA+ ++ D + + + D + L+++ SSL
Sbjct: 134 TKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSSQSSL 182
>Hs11641283 [R] KOG0490 Transcription factor contains HOX domain
Length = 402
Score = 55.8 bits (133), Expect = 2e-07
Identities = 31/135 (22%), Positives = 63/135 (45%), Gaps = 11/135 (8%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C + ++ + + N L WH C +C C S++ C+ + + YC+ F
Sbjct: 5 CAGCERPILDRFLL----NVLDRAWHIKCVQCCECKTNLSEK--CFSREGKLYCKNDFFR 58
Query: 535 KNNSICKVC-NGFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYVFNHEHTICNRH 591
+ + C C G + + +++ FH +C C +C K + G++ YV + +C
Sbjct: 59 RFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDD 118
Query: 592 DI--NTLKETGVSSL 604
+ ++LKE ++S+
Sbjct: 119 YLSSSSLKEGSLNSV 133
>7298537 [K] KOG4577 Transcription factor LIM3 contains LIM and HOX domains
Length = 440
Score = 54.7 bits (130), Expect = 4e-07
Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C CH+ ++ + I E WH C +C C + + C+ + Q +C+ F +
Sbjct: 42 CGGCHELILDRFILKVLERT----WHAKCLQCSECHGQLNDK--CFARNGQLFCKEDFFK 95
Query: 535 KNNSICKVCN-GFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYVFNHEHTICNRH 591
+ + C C+ G + + ++ +H C C +C++ + G ++Y+ IC R
Sbjct: 96 RYGTKCSACDMGIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKR- 154
Query: 592 DINTLKETGV---SSLPADQ 608
D K G+ SL DQ
Sbjct: 155 DYEEAKAKGLYLDGSLDGDQ 174
>Hs4504737 [R] KOG0490 Transcription factor contains HOX domain
Length = 346
Score = 54.3 bits (129), Expect = 5e-07
Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 498 QWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVCN-GFIEGECLENDK 556
+WH C KC C++ + C++ D + YC+ + C C+ GF + + + +
Sbjct: 34 EWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRAR 93
Query: 557 NERFHPSCLKCYICAK-VIGQDYYVFNHEHTICNR-HDI 593
++ +H C +C C++ +I D + + C HD+
Sbjct: 94 SKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDV 132
>Hs15375314 [K] KOG4577 Transcription factor LIM3 contains LIM and HOX domains
Length = 390
Score = 54.3 bits (129), Expect = 5e-07
Identities = 35/146 (23%), Positives = 59/146 (39%), Gaps = 14/146 (9%)
Query: 464 PMEVYPPGHGPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILD 523
PM+ P C C++ ++ K I L WH C KC C + R C+
Sbjct: 23 PMQQIPQ----CAGCNQHILDKFILKV----LDRHWHSSCLKCADCQMQLADR--CFSRA 72
Query: 524 DQPYCQLHFHEKNNSICKVC-NGFIEGECLENDKNERFHPSCLKCYICAKVI--GQDYYV 580
YC+ F ++ + C C G + + ++ +H C C IC + + G ++Y+
Sbjct: 73 GSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYL 132
Query: 581 FNHEHTICNRHDINTLKETGVSSLPA 606
+C + D T K+ S A
Sbjct: 133 MEDGRLVC-KEDYETAKQNDDSEAGA 157
>7291703 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 287
Score = 53.9 bits (128), Expect = 7e-07
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 7/114 (6%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C ++ +G+ + +WH CF+C++CSK + ++ +C+ HF E
Sbjct: 165 CSACRTPILERGVAAAER-----KWHEKCFRCVSCSKSLVS-ASFFEVNGYLFCKAHFRE 218
Query: 535 KNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTIC 588
+S C C I+ + + ++H C KC+ C K I + + IC
Sbjct: 219 LFSSRCAGCEKPIDRRAVV-ALSTKWHAKCFKCHHCRKRISAREFWIENGQPIC 271
>HsM4503721 [TZR] KOG1704 FOG: LIM domain
Length = 280
Score = 53.5 bits (127), Expect = 9e-07
Identities = 33/118 (27%), Positives = 53/118 (43%), Gaps = 10/118 (8%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPY---CQLH 531
C C+K + GI + + WH CF C+TCSK + + ++DQ Y C +
Sbjct: 162 CVKCNKAITSGGITYQDQ-----PWHADCFVCVTCSKKLAGQ-RFTAVEDQYYCVDCYKN 215
Query: 532 FHEKNNSICK-VCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTIC 588
F K + CK GF +G + + + +H C C C+ + +VF+ E C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
>Hs21361122 [TZR] KOG1704 FOG: LIM domain
Length = 280
Score = 53.5 bits (127), Expect = 9e-07
Identities = 33/118 (27%), Positives = 53/118 (43%), Gaps = 10/118 (8%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPY---CQLH 531
C C+K + GI + + WH CF C+TCSK + + ++DQ Y C +
Sbjct: 162 CVKCNKAITSGGITYQDQ-----PWHADCFVCVTCSKKLAGQ-RFTAVEDQYYCVDCYKN 215
Query: 532 FHEKNNSICK-VCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTIC 588
F K + CK GF +G + + + +H C C C+ + +VF+ E C
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
>SPBC4F6.12 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 438
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/165 (27%), Positives = 69/165 (41%), Gaps = 22/165 (13%)
Query: 425 SNSTPTFYNFHK---ESHEPIQTPPEKIRDSL------------PRQQELHEQTPMEVYP 469
SN P ++FH S P+ TP ++ +L P H T +Y
Sbjct: 192 SNRRPALHSFHSAPANSLYPLPTPTSQLPSNLSSNNLFQSDSLKPSMVSSHTSTKPVLYR 251
Query: 470 PG-HGPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYC 528
C +C + I S +L H CFKC TCS+ + V Y + + YC
Sbjct: 252 GNSEKSCHSCGGSLRAGRIISASGKKL----HPQCFKCDTCSQNL-EHVGFYYREGKFYC 306
Query: 529 QLHFHEKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKV 573
L +HE+ + CK C IE + + + N+ FH + C C++V
Sbjct: 307 HLDYHEQFSPRCKHCKTPIEDQAV-HINNDWFHENHHFCAGCSEV 350
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 8/115 (6%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQW-HRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFH 533
C++C + + ++ ++ W H C CS+ F+ +PC DD +CQ +
Sbjct: 318 CKHCKTPIEDQAVH------INNDWFHENHHFCAGCSEVFNVNIPCIYRDDLYWCQTCYD 371
Query: 534 EKNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTIC 588
K CK C I G ++ E +H C C C ++G + Y IC
Sbjct: 372 NKYAVKCKKCRKPILGISVKGSDGE-YHSQCWTCGACNALLGDEGYFMIENTPIC 425
>HsM7706250 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 444
Score = 53.1 bits (126), Expect = 1e-06
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C+ C ++ I + LS WH CF C C PFS + + +P C+ HFH
Sbjct: 329 CQGCQGPILDNYI-----SALSLLWHPDCFVCRECFAPFSGG-SFFEHEGRPLCENHFHA 382
Query: 535 KNNSICKVCNGFIEGECLENDKNERFHPSCLKCYICAK 572
+ S+ C + G C+ + RFHP C C +
Sbjct: 383 RRGSLWPTCGLPVTGRCV-SALGRRFHPDHFACTFCLR 419
>CE27107 [R] KOG0490 Transcription factor contains HOX domain
Length = 409
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/116 (26%), Positives = 50/116 (42%), Gaps = 8/116 (6%)
Query: 499 WHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVCNGFIEGECLENDKNE 558
+H C +C C PF CY+ D C+ ++ C+ C + E + E
Sbjct: 130 YHNNCLRCQMCDIPFEYSDKCYVRDGVFLCRADHAKRYQKCCRKCEIPLNREDMVMKAKE 189
Query: 559 R-FHPSCLKCYICA-KVIGQDYYVFNHE-HTICNRH-----DINTLKETGVSSLPA 606
FH +C C+IC K+ DYY + + H C+ H +E V+++PA
Sbjct: 190 MIFHHACFVCFICGIKLNPGDYYTMSPQGHLYCHAHYNAVRSTVLCEEAAVATVPA 245
>CE23977 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 1353
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/118 (25%), Positives = 45/118 (37%), Gaps = 7/118 (5%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C K ++ + N L +WH CF C C KPF Y+ PYC+ ++
Sbjct: 1241 CNKCSKPIISDCL-----NALQKKWHPTCFTCAHCQKPFGNSA-FYLEQGLPYCEQDWNA 1294
Query: 535 KNNSICKVCNGFIE-GECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTICNRH 591
+ C C IE G+ FH +C C C + + + + C H
Sbjct: 1295 LFTTKCVSCRYPIEAGDRWVEALGNAFHSNCFTCARCNHNLEGESFFAKNGQPFCRLH 1352
>CE17366 [R] KOG0490 Transcription factor contains HOX domain
Length = 452
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/134 (23%), Positives = 57/134 (41%), Gaps = 15/134 (11%)
Query: 454 PRQQELHEQTPMEVYPPGHGPCRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPF 513
P +Q H Q PM V C C E+ + + N ++H C KC+ CS+P
Sbjct: 43 PVEQRQH-QPPMAV-------CAGCRLEISDRYFLRVNPNL---EFHAQCLKCVQCSRPL 91
Query: 514 SKRVPCYILDDQPYCQLHFHEKNNSICKVCNGFIEGE--CLENDKNERFHPSCLKCYICA 571
+ ++ + Q YC+ + + C C+G + + FH +C C C
Sbjct: 92 DENQTAFVKNGQTYCRDDYRRLFTTRCSRCHGDFDKTDLVMRAGPQNVFHLNCFACVACE 151
Query: 572 KVI--GQDYYVFNH 583
K + G+++ + N+
Sbjct: 152 KRLQTGEEFQIKNN 165
>CE03650 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 1424
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/118 (25%), Positives = 45/118 (37%), Gaps = 7/118 (5%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C K ++ + N L +WH CF C C KPF Y+ PYC+ ++
Sbjct: 1312 CNKCSKPIISDCL-----NALQKKWHPTCFTCAHCQKPFGNSA-FYLEQGLPYCEQDWNA 1365
Query: 535 KNNSICKVCNGFIE-GECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTICNRH 591
+ C C IE G+ FH +C C C + + + + C H
Sbjct: 1366 LFTTKCVSCRYPIEAGDRWVEALGNAFHSNCFTCARCNHNLEGESFFAKNGQPFCRLH 1423
>Hs11496885 [TZ] KOG1703 Adaptor protein Enigma and related PDZ-LIM proteins
Length = 457
Score = 50.8 bits (120), Expect = 6e-06
Identities = 28/118 (23%), Positives = 49/118 (40%), Gaps = 7/118 (5%)
Query: 475 CRNCHKEVVGKGIYSKHENELSGQWHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHE 534
C C K++ G+ +++ L WH CF C C P R Y+ + PYC+ + +
Sbjct: 341 CAKCKKKITGEIMHA-----LKMTWHVHCFTCAACKTPIRNRA-FYMEEGVPYCERDYEK 394
Query: 535 KNNSICKVCNGFIE-GECLENDKNERFHPSCLKCYICAKVIGQDYYVFNHEHTICNRH 591
+ C C+ I+ G+ +H +C C IC + + + +C H
Sbjct: 395 MFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
>Hs20539165 [T] KOG1701 Focal adhesion adaptor protein Paxillin and related LIM
proteins
Length = 373
Score = 50.4 bits (119), Expect = 8e-06
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 9/149 (6%)
Query: 441 PIQTPPEKIRDSLPRQQELHEQTPMEVYPPGHGP--CRNCHKEVVGKGIYSKHENELSGQ 498
P + P + P ++EL P E G C CHK V + + + + Q
Sbjct: 148 PAEGPSVQPGPLRPMEEEL-PPPPAEPVEKGASTDICAFCHKTVSPRELAVE---AMKRQ 203
Query: 499 WHRGCFKCITCSKPFSKRVPCYILDDQPYCQLHFHEKNNSICKVCNGFIEGECLENDKNE 558
+H CF C TC + + + Y D +P C+ + + C C + + +
Sbjct: 204 YHAQCFTCRTCRRQLAGQ-SFYQKDGRPLCEPCYQDTLER-CGKCGEVVRDHIIRA-LGQ 260
Query: 559 RFHPSCLKCYICAKVIGQDYYVFNHEHTI 587
FHPSC C CA+ IG + + ++ +
Sbjct: 261 AFHPSCFTCVTCARCIGDESFALGSQNEV 289
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,386,356
Number of Sequences: 60738
Number of extensions: 1601436
Number of successful extensions: 4648
Number of sequences better than 1.0e-05: 37
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 4522
Number of HSP's gapped (non-prelim): 91
length of query: 625
length of database: 30,389,216
effective HSP length: 112
effective length of query: 513
effective length of database: 23,586,560
effective search space: 12099905280
effective search space used: 12099905280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)