ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3450 check: MH T KOG1165 Signal transduction mechanisms Casein kinase (serine/threonine/tyrosine protein kinase)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3450 1193481 1194899 473
(473 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER123w [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 546 e-155
YHR135c [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 407 e-113
YNL154c [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 402 e-112
SPBP35G2.05c [T] KOG1165 Casein kinase (serine/threonine/tyrosin... 388 e-108
SPBC1347.06c [T] KOG1165 Casein kinase (serine/threonine/tyrosin... 369 e-102
SPAC1805.05 [T] KOG1165 Casein kinase (serine/threonine/tyrosine... 353 3e-97
At3g23340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 286 5e-77
HsM5579454 [T] KOG1165 Casein kinase (serine/threonine/tyrosine ... 286 6e-77
Hs21314778 [T] KOG1165 Casein kinase (serine/threonine/tyrosine ... 286 6e-77
Hs4758080 [T] KOG1165 Casein kinase (serine/threonine/tyrosine p... 285 8e-77
Hs11545751 [T] KOG1165 Casein kinase (serine/threonine/tyrosine ... 284 2e-76
7300125 [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 283 5e-76
At5g43320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 281 2e-75
At1g04440 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 276 5e-74
SPBC3H7.15 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 276 6e-74
Hs4503093 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 275 8e-74
Hs20544145 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 275 1e-73
Hs20149530 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 275 1e-73
At1g72710 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 274 2e-73
CE29604 [T] KOG1165 Casein kinase (serine/threonine/tyrosine pro... 273 3e-73
At1g03930 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 273 4e-73
At4g14340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 272 7e-73
At2g19470 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 271 1e-72
Hs19923746 [T] KOG1163 Casein kinase (serine/threonine/tyrosine ... 271 2e-72
At4g26100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 271 2e-72
Hs21624639 [T] KOG1163 Casein kinase (serine/threonine/tyrosine ... 270 3e-72
At4g28540 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 270 3e-72
At4g28880 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 270 5e-72
Hs17475657 [T] KOG1163 Casein kinase (serine/threonine/tyrosine ... 269 6e-72
At5g44100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 268 1e-71
At4g28860 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 268 2e-71
YPL204w [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 265 8e-71
CE05879 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 265 1e-70
CE00872 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 264 2e-70
7302004 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 262 9e-70
SPAC23C4.12 [T] KOG1164 Casein kinase (serine/threonine/tyrosine... 254 3e-67
7292798 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 253 4e-67
7296752 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 224 3e-58
7292762 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 218 2e-56
At4g08800 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 209 7e-54
ECU03g0910 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 205 1e-52
7295933 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 194 2e-49
7298405 [T] KOG1163 Casein kinase (serine/threonine/tyrosine pro... 165 1e-40
At3g13670 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 147 3e-35
At2g25760 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 147 3e-35
At5g18190 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 147 4e-35
At3g03940 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 143 5e-34
Hs20555151 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 120 3e-27
ECU11g1980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine ... 120 3e-27
CE06325 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 115 1e-25
CE01289 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 103 7e-22
CE28799 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 102 1e-21
Hs4507903 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 100 8e-21
CE29490 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 99 1e-20
CE01965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 99 1e-20
CE02142 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 98 2e-20
CE06632 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 98 3e-20
7304307 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 98 3e-20
CE16557 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 97 5e-20
CE14562 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 96 2e-19
CE06942 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 95 2e-19
CE18365 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 94 3e-19
CE02312 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 93 8e-19
CE27672 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 92 1e-18
CE22097 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 92 1e-18
CE05253 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 92 1e-18
CE08640 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 92 2e-18
CE09021 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 90 8e-18
CE03499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 89 1e-17
CE02210 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 89 1e-17
CE06796 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 88 2e-17
CE06688 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 87 5e-17
CE03754 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 87 7e-17
CE01982 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 87 7e-17
CE20743 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 86 1e-16
CE16168 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 86 1e-16
CE13469 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 86 2e-16
CE08953 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 85 3e-16
CE04892 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 84 5e-16
CE05212 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 84 6e-16
CE09980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 83 8e-16
CE07450 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 83 8e-16
CE25045 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 82 1e-15
CE19741 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 82 2e-15
CE12108 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 82 2e-15
CE15314 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 81 4e-15
CE05474 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 81 4e-15
CE15237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 80 5e-15
CE09979 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 80 5e-15
CE07449 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 80 5e-15
CE24572 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 80 7e-15
CE02393 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 80 7e-15
CE22732 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 79 1e-14
CE04522 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 79 1e-14
CE12690 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 78 3e-14
CE04980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 77 6e-14
CE15320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 76 1e-13
CE19439 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 75 2e-13
CE00935 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 75 2e-13
CE24727 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 75 2e-13
CE14744 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 74 4e-13
CE07685 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 73 8e-13
CE24851 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 72 2e-12
CE00873 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 72 2e-12
CE12416 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 71 3e-12
CE02499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 71 4e-12
CE01404 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 5e-12
CE16891 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 7e-12
CE18539 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 9e-12
CE09897 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 70 9e-12
Hs5454164 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 68 3e-11
7303521 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 68 3e-11
CE09428 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 66 1e-10
CE17237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 64 5e-10
CE20236 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 64 6e-10
CE02965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 64 6e-10
CE29038 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 63 8e-10
CE17143 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 62 2e-09
Hs7705993 [T] KOG1164 Casein kinase (serine/threonine/tyrosine p... 59 1e-08
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 59 2e-08
CE07205 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 58 3e-08
CE03487 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 58 4e-08
7300559 [T] KOG4279 Serine/threonine protein kinase 57 8e-08
CE04290 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 55 2e-07
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 55 3e-07
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 55 3e-07
CE02704 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 55 3e-07
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 53 1e-06
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 53 1e-06
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 53 1e-06
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 53 1e-06
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 52 1e-06
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 52 2e-06
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 52 2e-06
CE04444 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 52 2e-06
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 52 3e-06
7299536 [D] KOG0580 Serine/threonine protein kinase 51 3e-06
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 51 4e-06
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 51 4e-06
YPL141c [T] KOG0583 Serine/threonine protein kinase 50 6e-06
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 50 6e-06
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 50 6e-06
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 50 7e-06
CE29300 [T] KOG0694 Serine/threonine protein kinase 50 1e-05
CE29299 [T] KOG0694 Serine/threonine protein kinase 50 1e-05
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 50 1e-05
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 50 1e-05
>YER123w [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 524
Score = 546 bits (1407), Expect = e-155
Identities = 269/366 (73%), Positives = 297/366 (80%), Gaps = 15/366 (4%)
Query: 1 MSKRSSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNG-----GSKN---------PVAIK 46
MS+RSSQH+VGIHYAVGPK L+ GSK PVAIK
Sbjct: 1 MSQRSSQHIVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIK 60
Query: 47 FEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSR 106
FEPR SD+PQLRDEFRAYRILN GIPHAYYF QEG+HNILIIDLLGPSLEDLFEWC R
Sbjct: 61 FEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGR 120
Query: 107 KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGG 166
KFSVKTT M+AKQMIDRVR+IH+HDLIYRDIKPDNFLIS++QR +G V+KSCA+SS
Sbjct: 121 KFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNN 180
Query: 167 DANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLG 226
D NLIY+VDFGMAKQ+RDP TKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLG
Sbjct: 181 DPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLG 240
Query: 227 HVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTD-LLTPEIPKQFAEYLSYCRSL 285
HVFFYFLRGSLPWQGLKA NNK KYEKIG+TKQ+L P D LL IP QFA YL Y RSL
Sbjct: 241 HVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSL 300
Query: 286 RFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQGWNIKVNKRVNLHGYGNPTPR 345
+FD+DPDYDYLISLM ++ N ++DGHYDWMDLNGG+GWNIK+N+R NLHGYGNP PR
Sbjct: 301 KFDEDPDYDYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGNPNPR 360
Query: 346 NTKHSA 351
++A
Sbjct: 361 VNGNTA 366
>YHR135c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 538
Score = 407 bits (1045), Expect = e-113
Identities = 199/347 (57%), Positives = 239/347 (68%), Gaps = 20/347 (5%)
Query: 2 SKRSSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEF 61
S R +VG+HY +G K +NG PVAIKFEPR++++PQLRDE+
Sbjct: 57 SSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGV---PVAIKFEPRKTEAPQLRDEY 113
Query: 62 RAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMI 121
+ Y+ILN IP+AYYF QEG+HNIL+IDLLGPSLEDLF+WC RKFSVKT +A QMI
Sbjct: 114 KTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMI 173
Query: 122 DRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQ 181
+ +H HDLIYRDIKPDNFLI DAN I+++DFGMAKQ
Sbjct: 174 TLIEDLHAHDLIYRDIKPDNFLIGR----------------PGQPDANNIHLIDFGMAKQ 217
Query: 182 FRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
+RDP TKQHIPYRE+KSLSGTARYMSINTH GREQSRRDD+E+LGHVFFYFLRG LPWQG
Sbjct: 218 YRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQG 277
Query: 242 LKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMT 301
LKA NNK KYEKIG K+ D L +P QF YL RSL F++ PDY+ L+
Sbjct: 278 LKAPNNKQKYEKIGEKKRSTNVYD-LAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLL 336
Query: 302 QIMQENGYEEDGHYDWMDLNGGQGWNIKVNKRVNLHGYGNPTPRNTK 348
++ + G DG YDWM LN G+GW++ +NK+ NLHGYG+P P N K
Sbjct: 337 SVLDDLGETADGQYDWMKLNDGRGWDLNINKKPNLHGYGHPNPPNEK 383
>YNL154c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 546
Score = 402 bits (1034), Expect = e-112
Identities = 195/345 (56%), Positives = 238/345 (68%), Gaps = 20/345 (5%)
Query: 4 RSSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRA 63
R +VG+HY +G K +NG PVAIKFEPR++++PQL+DE+R
Sbjct: 66 RDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMING---LPVAIKFEPRKTEAPQLKDEYRT 122
Query: 64 YRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDR 123
Y+IL GIP YYF QEG+HNIL+IDLLGPSLEDLF+WC R+FSVKT +A QMI
Sbjct: 123 YKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITL 182
Query: 124 VRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFR 183
+ +H HDLIYRDIKPDNFLI DAN ++++DFGMAKQ+R
Sbjct: 183 IEDLHAHDLIYRDIKPDNFLIGR----------------PGQPDANKVHLIDFGMAKQYR 226
Query: 184 DPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLK 243
DP TKQHIPYRE+KSLSGTARYMSINTH GREQSRRDD+E++GHVFFYFLRG LPWQGLK
Sbjct: 227 DPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLK 286
Query: 244 ALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQI 303
A NNK KYEKIG K+RL L +P QF YL R+L F++ PDY+ L+ +
Sbjct: 287 APNNKQKYEKIG-EKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSV 345
Query: 304 MQENGYEEDGHYDWMDLNGGQGWNIKVNKRVNLHGYGNPTPRNTK 348
+ + G DG YDWM LNGG+GW++ +NK+ NLHGYG+P P N K
Sbjct: 346 LDDLGETADGQYDWMKLNGGRGWDLSINKKPNLHGYGHPNPPNEK 390
>SPBP35G2.05c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 435
Score = 388 bits (997), Expect = e-108
Identities = 223/481 (46%), Positives = 274/481 (56%), Gaps = 67/481 (13%)
Query: 5 SSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAY 64
S VVG+HY VG K LN +AIKFEP++S++PQLRDE+R Y
Sbjct: 3 SQTSVVGVHYRVGRKIGEGSFGVIFDGMNLLNN---QLIAIKFEPKKSEAPQLRDEYRTY 59
Query: 65 RILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRV 124
++L GIP+ YYF QEG+HNIL+IDLLGPSLEDLFEWC R+FSVKT AM AKQM+ RV
Sbjct: 60 KLLVGNAGIPNVYYFGQEGLHNILVIDLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRV 119
Query: 125 RSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRD 184
++IHE +L+YRDIKPDNFLI S +AN++Y+VDFGMAK +RD
Sbjct: 120 QTIHEKNLVYRDIKPDNFLIGR----------------PSSRNANMVYMVDFGMAKYYRD 163
Query: 185 PNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKA 244
P TKQHIPY ERKSLSGTARYMSINTH GREQSRRDDLESLGHVF YFLRGSLPWQGLKA
Sbjct: 164 PKTKQHIPYSERKSLSGTARYMSINTHLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKA 223
Query: 245 LNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIM 304
NNK KYEKI KQ ++L P +F++Y++Y RSL FD++PDY +L L ++
Sbjct: 224 ANNKHKYEKISEKKQSTSISELCA-GFPNEFSKYMTYVRSLEFDEEPDYAFLQELFDDVL 282
Query: 305 QENGYEEDGHYDWMDLNGGQGWNIKVNKRVNLHGYGNPTPRNTKHSAXXXXXXXXXXXXX 364
+ NG DG YDWM LN G+GW + + + K+
Sbjct: 283 RANGDTNDGVYDWMLLNDGKGWESSSSH------FSVVAMKRRKNYLGLNVVQNDDSRKK 336
Query: 365 XXXXXXXXXXXXXXXSRHDSRNYRSF----SQSTP-----NKSQKKNV--NSSMGNSRVR 413
RNY SF S++ P + KK + +SS G RVR
Sbjct: 337 NSTLQTQNMRFKSSYGVRGPRNYSSFDALPSKNAPLVRQEQSASKKTIYAHSSRGYDRVR 396
Query: 414 ---LSQ-GNGFVGPNVPLKQNLNIQSYDSMGKLHGRRIPNNEEYDDNDSIEEGGFFSKLC 469
+SQ N VG N P D++DS +GGFF +C
Sbjct: 397 PMYVSQPSNNAVGVNHP--------------------------NDNSDSEAKGGFFDMIC 430
Query: 470 C 470
C
Sbjct: 431 C 431
>SPBC1347.06c [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 446
Score = 369 bits (946), Expect = e-102
Identities = 187/319 (58%), Positives = 222/319 (68%), Gaps = 20/319 (6%)
Query: 8 HVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRIL 67
+VVG+HY VG + LN VAIKFEPRRSD+PQLRDE+R Y++L
Sbjct: 6 NVVGVHYKVGRRIGEGSFGVIFEGTNLLNN---QQVAIKFEPRRSDAPQLRDEYRTYKLL 62
Query: 68 NDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSI 127
GIP+ YYF QEG+HNIL+IDLLGPSLEDL + C RKFSVKT AM AKQM+ RV+SI
Sbjct: 63 AGCTGIPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSI 122
Query: 128 HEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNT 187
HE L+YRDIKPDNFLI + +AN+IYVVDFGM K +RDP T
Sbjct: 123 HEKSLVYRDIKPDNFLIGR----------------PNSKNANMIYVVDFGMVKFYRDPVT 166
Query: 188 KQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNN 247
KQHIPYRE+K+LSGTARYMSINTH GREQSRRDDLE+LGHVF YFLRGSLPWQGLKA N
Sbjct: 167 KQHIPYREKKNLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGSLPWQGLKAATN 226
Query: 248 KAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQEN 307
K KYE+IG KQ P L P++F +Y+ Y R+L FD PDYDYL L +++++
Sbjct: 227 KQKYERIGEKKQS-TPLRELCAGFPEEFYKYMHYARNLAFDATPDYDYLQGLFSKVLERL 285
Query: 308 GYEEDGHYDWMDLNGGQGW 326
ED ++DW LN G+GW
Sbjct: 286 NTTEDENFDWNLLNNGKGW 304
>SPAC1805.05 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 439
Score = 353 bits (906), Expect = 3e-97
Identities = 178/329 (54%), Positives = 221/329 (67%), Gaps = 20/329 (6%)
Query: 5 SSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAY 64
S +VVG+HY VG K +N P+A+KFE R+S+ PQLRDE+ Y
Sbjct: 6 SHSNVVGVHYRVGKKIGEGSFGMLFQGVNLINN---QPIALKFESRKSEVPQLRDEYLTY 62
Query: 65 RILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRV 124
++L + GIP YY+ QEG++N+L++DLLGPSLEDLF++C R+FS KT AM+AKQMI R+
Sbjct: 63 KLLMGLPGIPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRI 122
Query: 125 RSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRD 184
+S+HE IYRDIKPDNFLI GS + N+IY VDFGMAKQ+RD
Sbjct: 123 QSVHERHFIYRDIKPDNFLIG------FPGSKTE----------NVIYAVDFGMAKQYRD 166
Query: 185 PNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKA 244
P T H PY E KSLSGTARYMSINTH GREQSRRDDLES+GHVF YFLRGSLPWQGLKA
Sbjct: 167 PKTHVHRPYNEHKSLSGTARYMSINTHLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKA 226
Query: 245 LNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIM 304
NK KYEKIG K+++ P L PK+F +Y+ Y R+L +++ PDYDYL SL ++
Sbjct: 227 ATNKQKYEKIG-EKKQVTPLKELCEGYPKEFLQYMIYARNLGYEEAPDYDYLRSLFDSLL 285
Query: 305 QENGYEEDGHYDWMDLNGGQGWNIKVNKR 333
+DG YDW LN G+GW K+
Sbjct: 286 LRINETDDGKYDWTLLNNGKGWQYSAAKQ 314
>At3g23340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 442
Score = 286 bits (732), Expect = 5e-77
Identities = 154/344 (44%), Positives = 201/344 (57%), Gaps = 25/344 (7%)
Query: 8 HVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRIL 67
HV+G + +G K +N + VA+K EP ++ PQL E + Y +L
Sbjct: 3 HVIGGKFKLGRKIGSGSFGELYIG---INVQTGEEVALKLEPVKTKHPQLHYESKVYMLL 59
Query: 68 NDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSI 127
G+PH +F EG +N + IDLLGPSLEDLF +C+R FS+KT MLA Q+I+RV +
Sbjct: 60 QGGTGVPHIKWFGVEGNYNCMAIDLLGPSLEDLFNYCTRSFSLKTVLMLADQLINRVEYM 119
Query: 128 HEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNT 187
H ++RDIKPDNFL+ G AN +Y++D+G+AK++RD T
Sbjct: 120 HSRGFLHRDIKPDNFLMG------------------LGRKANQVYIIDYGLAKKYRDLQT 161
Query: 188 KQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNN 247
+HIPYRE K+L+GTARY S+NTH G EQSRRDDLESLG+V YF+RGSLPWQGLKA
Sbjct: 162 HKHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMYFIRGSLPWQGLKAGTK 221
Query: 248 KAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQEN 307
K KYEKI K+ L P ++L P +F Y YCRSLRF+ PDY YL L +
Sbjct: 222 KQKYEKIS-EKKMLTPVEVLCKSYPSEFTSYFHYCRSLRFEDKPDYSYLKRLFRDLFIRE 280
Query: 308 GYEEDGHYDWMDLNGGQGWNI---KVNKRVNLHGYGNPTPRNTK 348
GY+ D +DW L Q +I + N + L G RN K
Sbjct: 281 GYQFDYVFDWTILKYPQSGSISKPRPNPKPALDPPGPSAERNEK 324
>HsM5579454 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 415
Score = 286 bits (731), Expect = 6e-77
Identities = 141/275 (51%), Positives = 185/275 (67%), Gaps = 17/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK EP +S +PQL E+R Y+ L+ G+P YYF G +N ++++LLGPSLEDLF+
Sbjct: 72 VAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFD 131
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
C R F++KT M+A Q+I R+ +H LIYRD+KP+NFL+ +
Sbjct: 132 LCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQ---------- 181
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
+ I+++DFG+AK++ DP TK+HIPYRE KSL+GTARYMSINTH G+EQSRRDDL
Sbjct: 182 ------HAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDL 235
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
E+LGH+F YFLRGSLPWQGLKA K +Y+KIG TK R P ++L P++ A YL Y
Sbjct: 236 EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK-RATPIEVLCENFPEEMATYLRYV 294
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
R L F + PDYDYL L T + +G+ D YDW
Sbjct: 295 RRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
>Hs21314778 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 415
Score = 286 bits (731), Expect = 6e-77
Identities = 141/275 (51%), Positives = 185/275 (67%), Gaps = 17/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK EP +S +PQL E+R Y+ L+ G+P YYF G +N ++++LLGPSLEDLF+
Sbjct: 72 VAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGNYNAMVLELLGPSLEDLFD 131
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
C R F++KT M+A Q+I R+ +H LIYRD+KP+NFL+ +
Sbjct: 132 LCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQ---------- 181
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
+ I+++DFG+AK++ DP TK+HIPYRE KSL+GTARYMSINTH G+EQSRRDDL
Sbjct: 182 ------HAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDL 235
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
E+LGH+F YFLRGSLPWQGLKA K +Y+KIG TK R P ++L P++ A YL Y
Sbjct: 236 EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK-RATPIEVLCENFPEEMATYLRYV 294
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
R L F + PDYDYL L T + +G+ D YDW
Sbjct: 295 RRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDW 329
>Hs4758080 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 447
Score = 285 bits (730), Expect = 8e-77
Identities = 144/276 (52%), Positives = 185/276 (66%), Gaps = 18/276 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK EP +S +PQL E+R Y+ L GIP YYF G +N ++++LLGPSLEDLF+
Sbjct: 69 VAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFD 128
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
C R FS+KT M+A Q+I R+ +H +LIYRD+KP+NFLI + +
Sbjct: 129 LCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPRNKTQQ--------- 179
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
+I+++DFG+AK++ DP TK+HIPYRE KSL+GTARYMSINTH G+EQSRRDDL
Sbjct: 180 -------VIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDL 232
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
E+LGH+F YFLRGSLPWQGLKA K +Y+KIG TK R P ++L P + A YL Y
Sbjct: 233 EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK-RATPIEVLCENFP-EMATYLRYV 290
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWM 318
R L F + PDY+YL L T + GY D YDW+
Sbjct: 291 RRLDFFEKPDYEYLRKLFTDLFDRKGYMFDYEYDWI 326
>Hs11545751 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 393
Score = 284 bits (726), Expect = 2e-76
Identities = 141/277 (50%), Positives = 187/277 (66%), Gaps = 18/277 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDV-RGIPHAYYFSQEGIHNILIIDLLGPSLEDLF 101
VAIK EP +S +PQL E+R Y+ L G+P YYF G +N ++++LLGPSLEDLF
Sbjct: 70 VAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLF 129
Query: 102 EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCA 161
+ C R F++KT M+A Q++ R+ +H +LIYRD+KP+NFLI
Sbjct: 130 DLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGR--------------- 174
Query: 162 TSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDD 221
++I+++DFG+AK++ DP TK+HIPYRE KSL+GTARYMSINTH G+EQSRRDD
Sbjct: 175 -QGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDD 233
Query: 222 LESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSY 281
LE+LGH+F YFLRGSLPWQGLKA K +Y+KIG TK R P + L P++ A YL Y
Sbjct: 234 LEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK-RNTPIEALCENFPEEMATYLRY 292
Query: 282 CRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWM 318
R L F + PDY+YL +L T + ++ GY D YDW+
Sbjct: 293 VRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWV 329
>7300125 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 422
Score = 283 bits (723), Expect = 5e-76
Identities = 139/276 (50%), Positives = 187/276 (67%), Gaps = 18/276 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILND-VRGIPHAYYFSQEGIHNILIIDLLGPSLEDLF 101
VAIK EP +S +PQL E+R Y++L G+P YYF G +N L+++LLGPSLEDLF
Sbjct: 47 VAIKMEPMKSKAPQLHLEYRFYKLLGSHAEGVPEVYYFGPCGKYNALVMELLGPSLEDLF 106
Query: 102 EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCA 161
+ C R+F++K+ ++A Q++ R+ +H LIYRD+KP+NFLI
Sbjct: 107 DICGRRFTLKSVLLIAIQLLHRIEYVHSRHLIYRDVKPENFLIGR--------------- 151
Query: 162 TSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDD 221
+S +I+++DFG+AK++ D +T +HIPYRE KSL+GTARYMSINTH GREQSRRDD
Sbjct: 152 -TSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSRRDD 210
Query: 222 LESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSY 281
LE+LGH+F YFLRGSLPWQGLKA K +Y+KIG TK R P ++L P++FA YL Y
Sbjct: 211 LEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK-RATPIEVLCDGHPEEFATYLRY 269
Query: 282 CRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
R L F + PDYD+L L + GY ++G +DW
Sbjct: 270 VRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDW 305
>At5g43320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 480
Score = 281 bits (718), Expect = 2e-75
Identities = 146/309 (47%), Positives = 188/309 (60%), Gaps = 22/309 (7%)
Query: 9 VVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILN 68
VVG Y +G K G VA+K EP R+ PQL E + Y +L
Sbjct: 4 VVGGKYKLGRKLGSGSFGELFLGVNVQTG---EEVAVKLEPARARHPQLHYESKLYMLLQ 60
Query: 69 DVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIH 128
GIPH ++ EG +N ++IDLLGPS+EDLF +CSR+F++KT MLA QMI+RV +H
Sbjct: 61 GGTGIPHLKWYGVEGEYNCMVIDLLGPSMEDLFNYCSRRFNLKTVLMLADQMINRVEYMH 120
Query: 129 EHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTK 188
++RDIKPDNFL+ G AN +Y++D+G+AK++RD T
Sbjct: 121 VRGFLHRDIKPDNFLMG------------------LGRKANQVYIIDYGLAKKYRDLQTH 162
Query: 189 QHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNK 248
+HIPYRE K+L+GTARY S+NTH G EQSRRDDLESLG+V YFLRGSLPWQGL+A K
Sbjct: 163 RHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMYFLRGSLPWQGLRAGTKK 222
Query: 249 AKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENG 308
KY+KI K+RL P ++L P +F Y Y RSLRF+ PDY YL L + G
Sbjct: 223 QKYDKIS-EKKRLTPVEVLCKSFPPEFTSYFLYVRSLRFEDKPDYPYLKRLFRDLFIREG 281
Query: 309 YEEDGHYDW 317
Y+ D +DW
Sbjct: 282 YQFDYVFDW 290
>At1g04440 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 468
Score = 276 bits (706), Expect = 5e-74
Identities = 138/275 (50%), Positives = 177/275 (64%), Gaps = 19/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VA+K EP R+ PQL E + Y +L GIPH +F EG N ++IDLLGPS+E+ F
Sbjct: 35 VAVKLEPLRARHPQLHYESKLYMLLQGGTGIPHLKWFGVEGEFNCMVIDLLGPSMEEFFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+CSR FS+KT MLA QMI+RV +H ++RDIKPDNFL+
Sbjct: 95 YCSRSFSLKTVLMLADQMINRVEYMHVKGFLHRDIKPDNFLMG----------------- 137
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G AN +Y++D+G+AK++RD T +HIPYRE K+L+GTARY S+NTH G EQSRRDDL
Sbjct: 138 -LGRKANQVYIIDYGLAKKYRDLQTHKHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG++ YFLRGSLPWQGL+A K KY+KI K+RL P ++L P +F Y Y
Sbjct: 197 ESLGYLLMYFLRGSLPWQGLRAGTKKQKYDKIS-EKKRLTPVEVLCKNFPPEFTSYFLYV 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
RSLRF+ PDY YL L + GY+ D +DW
Sbjct: 256 RSLRFEDKPDYSYLKRLFRDLFIREGYQFDYVFDW 290
>SPBC3H7.15 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 365
Score = 276 bits (705), Expect = 6e-74
Identities = 147/308 (47%), Positives = 188/308 (60%), Gaps = 22/308 (7%)
Query: 10 VGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILND 69
+G Y +G K ++G VAIK E R+ PQL E+R YRIL+
Sbjct: 7 IGNKYRIGRKIGSGSFGDIYLGTNVVSG---EEVAIKLESTRAKHPQLEYEYRVYRILSG 63
Query: 70 VRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHE 129
GIP +F E +N +++DLLGPSLEDLF +C+RKFS+KT +LA Q+I R+ IH
Sbjct: 64 GVGIPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIHS 123
Query: 130 HDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQ 189
++RDIKPDNFL+ +R N + ++DFG+AK++RD T
Sbjct: 124 KSFLHRDIKPDNFLMGIGKR------------------GNQVNIIDFGLAKKYRDHKTHL 165
Query: 190 HIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKA 249
HIPYRE K+L+GTARY SINTH G EQSRRDDLESLG+V YF RGSLPWQGLKA K
Sbjct: 166 HIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQ 225
Query: 250 KYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGY 309
KYEKI + K+ PT++L P++F+ YL+Y RSLRFD PDY YL L + Y
Sbjct: 226 KYEKI-MEKKISTPTEVLCRGFPQEFSIYLNYTRSLRFDDKPDYAYLRKLFRDLFCRQSY 284
Query: 310 EEDGHYDW 317
E D +DW
Sbjct: 285 EFDYMFDW 292
>Hs4503093 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 416
Score = 275 bits (704), Expect = 8e-74
Identities = 141/292 (48%), Positives = 183/292 (62%), Gaps = 19/292 (6%)
Query: 36 NGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGP 95
N S VAIK E ++ PQL E + Y+++ GIP + EG +N+++++LLGP
Sbjct: 28 NIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGP 87
Query: 96 SLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGS 155
SLEDLF +CSRKFS+KT +LA QMI R+ IH + I+RD+KPDNFL+
Sbjct: 88 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG---------- 137
Query: 156 VVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGRE 215
G NL+Y++DFG+AK++RD T QHIPYRE K+L+GTARY SINTH G E
Sbjct: 138 --------LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIE 189
Query: 216 QSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQF 275
QSRRDDLESLG+V YF GSLPWQGLKA + KYE+I K+ P ++L P +F
Sbjct: 190 QSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERIS-EKKMSTPIEVLCKGYPSEF 248
Query: 276 AEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQGWN 327
+ YL++CRSLRFD PDY YL L + G+ D +DW L G N
Sbjct: 249 STYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN 300
>Hs20544145 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 409
Score = 275 bits (702), Expect = 1e-73
Identities = 139/281 (49%), Positives = 180/281 (63%), Gaps = 19/281 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E ++ PQL E + Y+++ GIP + EG +N+++++LLGPSLEDLF
Sbjct: 35 VAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+CSRKFS+KT +LA QMI R+ IH + I+RD+KPDNFL+
Sbjct: 95 FCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG----------------- 137
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G NL+Y++DFG+AK++RD T QHIPYRE K+L+GTARY SINTH G EQSRRDDL
Sbjct: 138 -LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG+V YF GSLPWQGLKA + KYE+I K+ P ++L P +FA YL++C
Sbjct: 197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERIS-EKKMSTPIEVLCKGYPSEFATYLNFC 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGG 323
RSLRFD PDY YL L + G+ D +DW L G
Sbjct: 256 RSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG 296
>Hs20149530 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 415
Score = 275 bits (702), Expect = 1e-73
Identities = 139/281 (49%), Positives = 180/281 (63%), Gaps = 19/281 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E ++ PQL E + Y+++ GIP + EG +N+++++LLGPSLEDLF
Sbjct: 35 VAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+CSRKFS+KT +LA QMI R+ IH + I+RD+KPDNFL+
Sbjct: 95 FCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG----------------- 137
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G NL+Y++DFG+AK++RD T QHIPYRE K+L+GTARY SINTH G EQSRRDDL
Sbjct: 138 -LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG+V YF GSLPWQGLKA + KYE+I K+ P ++L P +FA YL++C
Sbjct: 197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERIS-EKKMSTPIEVLCKGYPSEFATYLNFC 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGG 323
RSLRFD PDY YL L + G+ D +DW L G
Sbjct: 256 RSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFG 296
>At1g72710 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 465
Score = 274 bits (700), Expect = 2e-73
Identities = 142/275 (51%), Positives = 179/275 (64%), Gaps = 20/275 (7%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E ++ PQL E + Y++L G+P+ ++ EG +N+L+IDLLGPSLEDLF
Sbjct: 35 VAIKLENVKTKHPQLLYESKLYKVLQGGTGVPNVKWYGVEGDYNVLVIDLLGPSLEDLFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+CSRK S+KT MLA QMI+R+ +H+ ++RDIKPDNFL+
Sbjct: 95 FCSRKLSLKTVLMLADQMINRIEFVHQKSFLHRDIKPDNFLM------------------ 136
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G AN +YV+DFG+AK++RD N QHIPYRE K+L+GTARY S+NTH G EQSRRDDL
Sbjct: 137 GLGRRANQVYVIDFGLAKKYRDSN-HQHIPYRENKNLTGTARYASMNTHLGIEQSRRDDL 195
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG V YFL+GSLPWQGLKA N K KYEKI K+ + L P +FA Y YC
Sbjct: 196 ESLGFVLMYFLKGSLPWQGLKAGNKKQKYEKIS-EKKVSTSIEALCRGYPSEFASYFHYC 254
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
RSLRFD PDY YL L + G++ D +DW
Sbjct: 255 RSLRFDDKPDYAYLKRLFRDLFIREGFQFDYVFDW 289
>CE29604 [T] KOG1165 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 407
Score = 273 bits (699), Expect = 3e-73
Identities = 136/275 (49%), Positives = 183/275 (66%), Gaps = 17/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK EP +S +PQL E+R Y++L G+P +YF G +N L+++LLG SLEDLF+
Sbjct: 54 VAIKLEPMKSKAPQLHLEYRFYKLLGQAEGLPQVHYFGPCGKYNALVMELLGHSLEDLFD 113
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
C R FS+KT AM+A Q+I R+ +H LIYRD+KP+NFLI +
Sbjct: 114 LCDRHFSLKTVAMVAMQLIRRIEYVHTKHLIYRDVKPENFLIGRY--------------- 158
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
S ++++++DFG+AK++ D +T +HI YRE KSL+GTARYMSINTH G+EQSRRDDL
Sbjct: 159 -STRKQHVLHIIDFGLAKEYIDCDTGKHIAYREHKSLTGTARYMSINTHLGKEQSRRDDL 217
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
E+LGH+F YFLRGSLPWQGLKA K +Y+KIG TK R ++L P +FA+YL Y
Sbjct: 218 EALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTK-RQTAVEVLCEGFPDEFAQYLRYA 276
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
R L F + PDYD+ +L ++ G D +DW
Sbjct: 277 RRLDFFETPDYDFCYNLFKSVLDRLGATYDYEFDW 311
>At1g03930 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 471
Score = 273 bits (698), Expect = 4e-73
Identities = 141/309 (45%), Positives = 189/309 (60%), Gaps = 20/309 (6%)
Query: 35 LNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLG 94
+N + VA+K E ++ PQL E + Y +L G+P+ ++ EG +N+++IDLLG
Sbjct: 27 INVQTGEEVAVKLESVKTKHPQLHYESKLYMLLQGGTGVPNLKWYGVEGDYNVMVIDLLG 86
Query: 95 PSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
PSLEDLF +C+RK S+KT MLA Q+I+RV +H ++RDIKPDNFL+
Sbjct: 87 PSLEDLFNYCNRKLSLKTVLMLADQLINRVEFMHTRGFLHRDIKPDNFLMG--------- 137
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
G AN +Y++DFG+ K++RD T +HIPYRE K+L+GTARY S+NTH G
Sbjct: 138 ---------LGRKANQVYIIDFGLGKKYRDLQTHRHIPYRENKNLTGTARYASVNTHLGV 188
Query: 215 EQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQ 274
EQSRRDDLE+LG+V YFL+GSLPWQGLKA K KY++I K+ P ++L P +
Sbjct: 189 EQSRRDDLEALGYVLMYFLKGSLPWQGLKAGTKKQKYDRIS-EKKVATPIEVLCKNQPSE 247
Query: 275 FAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQ-GWNIKVNKR 333
F Y YCRSLRFD PDY YL L + GY+ D +DW L Q G + + R
Sbjct: 248 FVSYFRYCRSLRFDDKPDYSYLKRLFRDLFIREGYQFDYVFDWTVLKYPQIGSSSGSSSR 307
Query: 334 VNLHGYGNP 342
H NP
Sbjct: 308 TRNHTTANP 316
>At4g14340 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 457
Score = 272 bits (696), Expect = 7e-73
Identities = 141/310 (45%), Positives = 186/310 (59%), Gaps = 22/310 (7%)
Query: 8 HVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRIL 67
HV+G + +G K G VA+K EP ++ PQL+ E + Y L
Sbjct: 9 HVIGGKFKLGRKLGSGSFGELYLGINIQTG---EEVAVKLEPVKTRHPQLQYESKIYMFL 65
Query: 68 NDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSI 127
G+PH +F EG ++ ++IDLLGPSLEDLF +C R FS+K+ MLA Q+I RV +
Sbjct: 66 QGGTGVPHLKWFGVEGEYSCMVIDLLGPSLEDLFNYCKRIFSLKSVLMLADQLICRVEYM 125
Query: 128 HEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNT 187
H ++RDIKPDNFL+ +R AN +Y++D+G+AK+++D T
Sbjct: 126 HSRGFLHRDIKPDNFLMGLGRR------------------ANQVYIIDYGLAKKYKDLQT 167
Query: 188 KQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNN 247
++HIPYRE K+L+GTARY S+NTH G EQSRRDDLESLG+V YFLRGSLPWQGLKA
Sbjct: 168 QKHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMYFLRGSLPWQGLKAGTK 227
Query: 248 KAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQEN 307
K KY+KI K+ L + L P +F Y YCRSLRF+ PDY YL L +
Sbjct: 228 KQKYDKIS-EKKMLTSVETLCKSYPSEFTSYFHYCRSLRFEDKPDYSYLRRLFRDLFIRE 286
Query: 308 GYEEDGHYDW 317
GY+ D +DW
Sbjct: 287 GYQLDYVFDW 296
>At2g19470 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 433
Score = 271 bits (694), Expect = 1e-72
Identities = 144/303 (47%), Positives = 186/303 (60%), Gaps = 31/303 (10%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E ++ PQL E R YR+L GIP+ ++ EG +N+L++DLLGPSLEDLF
Sbjct: 35 VAIKLESVKTAHPQLSYESRIYRVLQGGTGIPNMKWYGVEGDYNVLVMDLLGPSLEDLFS 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+C R+FS+KT MLA QMI+R+ IH ++RDIKPDNFL+ +R
Sbjct: 95 YCKRQFSLKTVLMLADQMINRLEFIHSKSYLHRDIKPDNFLMGLGRR------------- 141
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
AN +Y++D+G+AK++RD +T +HIPYRE KSL GT RY S+NTH G EQSRRDD+
Sbjct: 142 -----ANQVYIIDYGLAKKYRDSSTHRHIPYRENKSLIGTPRYASLNTHLGIEQSRRDDI 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG++ YFL+GSLPWQGLKA N K KY+KI K+ + L P +FA Y YC
Sbjct: 197 ESLGYILMYFLKGSLPWQGLKAGNKKQKYDKIS-EKKVSTSIETLCRGHPTEFASYFHYC 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQGWNIKVNKRVNLHGYGNP 342
RSLRFD PDY YL L + G++ D +DW Q + GNP
Sbjct: 256 RSLRFDDKPDYAYLKRLFRNLFIREGFQFDFVFDWTVYKYQQSQS------------GNP 303
Query: 343 TPR 345
PR
Sbjct: 304 QPR 306
>Hs19923746 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 271 bits (693), Expect = 2e-72
Identities = 143/316 (45%), Positives = 192/316 (60%), Gaps = 22/316 (6%)
Query: 2 SKRSSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEF 61
S ++ +VG Y + K NG VA+K E +++ PQL E
Sbjct: 5 SGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNG---EEVAVKLESQKARHPQLLYES 61
Query: 62 RAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMI 121
+ Y+IL GIPH ++ QE +N+L++DLLGPSLEDLF +CSR+F++KT MLA QMI
Sbjct: 62 KLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMI 121
Query: 122 DRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQ 181
R+ +H + I+RDIKPDNFL+ G N ++++DFG+AK+
Sbjct: 122 SRIEYVHTKNFIHRDIKPDNFLMG------------------IGRHCNKLFLIDFGLAKK 163
Query: 182 FRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
+RD T+QHIPYRE K+L+GTARY SIN H G EQSRRDD+ESLG+V YF R SLPWQG
Sbjct: 164 YRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQG 223
Query: 242 LKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMT 301
LKA K KYEKI K+ P ++L P +FA YL+YCR LRF++ PDY YL L
Sbjct: 224 LKAATKKKKYEKIS-EKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFR 282
Query: 302 QIMQENGYEEDGHYDW 317
+ + ++ D +DW
Sbjct: 283 ILFRTLNHQYDYTFDW 298
>At4g26100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 450
Score = 271 bits (692), Expect = 2e-72
Identities = 137/275 (49%), Positives = 178/275 (63%), Gaps = 19/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
+AIK E ++ PQL E + YRIL G+P+ +F EG +N+L++DLLGPSLEDLF
Sbjct: 35 LAIKLENVKTKHPQLLYESKLYRILQGGTGVPNVKWFGVEGDYNVLVMDLLGPSLEDLFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+CSRK S+K+ MLA QMI+RV H ++RD+KPDNFL+ +R
Sbjct: 95 FCSRKLSLKSVLMLADQMINRVEFFHSKSFLHRDLKPDNFLMGLGRR------------- 141
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
AN +Y++DFG+AK++RD T QHIPYRE K+L+GTARY S+NTH G EQSRRDDL
Sbjct: 142 -----ANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYASMNTHLGIEQSRRDDL 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG++ YFL+GSLPWQGLKA K KYE+I K+ + L P +FA Y YC
Sbjct: 197 ESLGYILMYFLKGSLPWQGLKAGTKKQKYERIS-EKKVSTSIEALCRGYPSEFASYFHYC 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
RSLRFD PDY YL + + G++ D +DW
Sbjct: 256 RSLRFDDKPDYAYLKRIFRDLFIREGFQFDYVFDW 290
>Hs21624639 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 270 bits (691), Expect = 3e-72
Identities = 143/316 (45%), Positives = 191/316 (60%), Gaps = 22/316 (6%)
Query: 2 SKRSSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEF 61
S ++ VVG Y + K NG VA+K E ++ PQL E
Sbjct: 5 SGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNG---EEVAVKLESQKVKHPQLLYES 61
Query: 62 RAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMI 121
+ Y IL GIPH +++ QE +N+L++DLLGPSLEDLF +CSR+F++KT MLA QMI
Sbjct: 62 KLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMI 121
Query: 122 DRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQ 181
R+ +H + ++RDIKPDNFL+ +G N ++++DFG+AK+
Sbjct: 122 SRIEYVHTKNFLHRDIKPDNFLMG------------------TGRHCNKLFLIDFGLAKK 163
Query: 182 FRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
+RD T+QHIPYRE K L GT RY SIN H G EQSRRDD+ESLG+VF YF R SLPWQG
Sbjct: 164 YRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQG 223
Query: 242 LKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMT 301
LKA+ K KYEKI K+ P ++L P +FA YL+YCR LRF++ PDY YL L
Sbjct: 224 LKAMTKKQKYEKIS-EKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFR 282
Query: 302 QIMQENGYEEDGHYDW 317
+ + ++ D +DW
Sbjct: 283 ILFRTLNHQYDYTFDW 298
>At4g28540 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 321
Score = 270 bits (691), Expect = 3e-72
Identities = 138/297 (46%), Positives = 183/297 (61%), Gaps = 22/297 (7%)
Query: 44 AIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEW 103
A+K EP ++ PQL E + Y +L GIP +F +G +N ++IDLLGPSLEDLF +
Sbjct: 36 AVKLEPAKTKHPQLHYESKIYMLLQGGSGIPSLKWFGVQGDYNAMVIDLLGPSLEDLFNY 95
Query: 104 CSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATS 163
C+R+ ++K MLA Q+I RV +H ++RDIKPDNFL+
Sbjct: 96 CNRRLTLKAVLMLADQLISRVEYMHSRGFLHRDIKPDNFLMG------------------ 137
Query: 164 SGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLE 223
G AN +Y++DFG+AK++RD T +HIPYRE K+L+GTARY S+NTH G EQSRRDDLE
Sbjct: 138 LGRKANQVYIIDFGLAKKYRDLQTHRHIPYRENKNLTGTARYASVNTHLGVEQSRRDDLE 197
Query: 224 SLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCR 283
SLG+V YFLRGSLPWQGLKA K KY++I K+ P ++L P +F Y YCR
Sbjct: 198 SLGYVLMYFLRGSLPWQGLKAGTKKQKYDRIS-EKKVSTPIEVLCKSYPPEFVSYFQYCR 256
Query: 284 SLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQG---WNIKVNKRVNLH 337
SLRF+ PDY YL L + GY+ D +DW L Q + ++RV+ H
Sbjct: 257 SLRFEDKPDYSYLKRLFRDLFIREGYQFDYVFDWTALKHPQSSARSHSSTHERVSTH 313
>At4g28880 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 307
Score = 270 bits (689), Expect = 5e-72
Identities = 137/270 (50%), Positives = 172/270 (62%), Gaps = 19/270 (7%)
Query: 48 EPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRK 107
E ++ PQL E + YRIL GIP +F +G N L++DLLGPSLEDLF +C RK
Sbjct: 40 ENSKTKHPQLLYEAKLYRILEGGSGIPRIKWFGVDGTENALVMDLLGPSLEDLFVYCGRK 99
Query: 108 FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGD 167
FS KT MLA QM+ R+ +H ++RDIKPDNFL+ G
Sbjct: 100 FSPKTVLMLADQMLTRIEFVHSKGYLHRDIKPDNFLMG------------------LGRK 141
Query: 168 ANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGH 227
AN +Y++DFG+AK++RD NT +HIPYRE K+L+GTARY S NTH G EQSRRDDLESLG+
Sbjct: 142 ANQVYLIDFGLAKRYRDANTNRHIPYRENKNLTGTARYASCNTHLGIEQSRRDDLESLGY 201
Query: 228 VFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRF 287
V YFLRGSLPWQGLKA++ K KY+KI K+ P ++L P +FA Y YC +L F
Sbjct: 202 VLLYFLRGSLPWQGLKAVDKKQKYDKI-CEKKISTPIEVLCKNHPVEFASYFHYCHTLTF 260
Query: 288 DQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
DQ PDY +L L + GYE D +DW
Sbjct: 261 DQRPDYGFLKRLFRDLFSREGYEFDYIFDW 290
>Hs17475657 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 269 bits (688), Expect = 6e-72
Identities = 142/316 (44%), Positives = 191/316 (59%), Gaps = 22/316 (6%)
Query: 2 SKRSSQHVVGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEF 61
S ++ VVG Y + K NG VA+K E ++ PQL E
Sbjct: 5 SGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNG---EDVAVKLESQKVKHPQLLYES 61
Query: 62 RAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMI 121
+ Y IL GIPH +++ QE +N+L++DLLGPSLEDLF +CSR+F++KT MLA QMI
Sbjct: 62 KLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMI 121
Query: 122 DRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQ 181
R+ +H + ++RDIKPDNFL+ +G N ++++DFG+AK+
Sbjct: 122 SRIEYVHTKNFLHRDIKPDNFLMG------------------TGRHCNKLFLIDFGLAKK 163
Query: 182 FRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
+RD T+QHIPYRE K L GT RY SIN H G EQSRRDD+ESLG+VF YF R SLPWQG
Sbjct: 164 YRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQG 223
Query: 242 LKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMT 301
L+A+ K KYEKI K+ P ++L P +FA YL+YCR LRF++ PDY YL L
Sbjct: 224 LRAMTKKQKYEKIS-EKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFR 282
Query: 302 QIMQENGYEEDGHYDW 317
+ + ++ D +DW
Sbjct: 283 ILFRTLNHQYDYTFDW 298
>At5g44100 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 476
Score = 268 bits (686), Expect = 1e-71
Identities = 133/275 (48%), Positives = 177/275 (64%), Gaps = 19/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VA+K E ++ PQL E + Y +L GIP+ +F EG +++++IDLLGPSLEDLF
Sbjct: 35 VAVKLENVKTKHPQLHYESKLYMLLQGGSGIPNIKWFGVEGDYSVMVIDLLGPSLEDLFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+C+RK ++KT MLA Q+++RV +H ++RDIKPDNFL+
Sbjct: 95 YCNRKLTLKTVLMLADQLLNRVEFMHTRGFLHRDIKPDNFLMG----------------- 137
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G AN +Y++DFG+ K++RD T +HIPYRE K+L+GTARY S+NTH G EQSRRDDL
Sbjct: 138 -LGRKANQVYIIDFGLGKKYRDLQTHKHIPYRENKNLTGTARYASVNTHLGVEQSRRDDL 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG+V YFL+GSLPWQGLKA K KY++I K+ P ++L P +F Y YC
Sbjct: 197 ESLGYVLMYFLKGSLPWQGLKAGTKKQKYDRIS-EKKVSTPIEVLCKNQPSEFVSYFHYC 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
RSLRFD PDY YL L + GY+ D +DW
Sbjct: 256 RSLRFDDKPDYSYLKRLFRDLFIREGYQFDYVFDW 290
>At4g28860 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 307
Score = 268 bits (684), Expect = 2e-71
Identities = 136/270 (50%), Positives = 170/270 (62%), Gaps = 19/270 (7%)
Query: 48 EPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRK 107
E ++ PQL E + YR L GIP +F +G N L++DLLGPSLEDLF +C RK
Sbjct: 40 ENSKTKHPQLLYEAKLYRTLEGGSGIPRIRWFGVDGTENALVMDLLGPSLEDLFVYCGRK 99
Query: 108 FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGD 167
FS KT MLA QM+ R+ +H ++RDIKPDNFL+ G
Sbjct: 100 FSPKTVLMLADQMLTRIEYVHSKGYLHRDIKPDNFLMG------------------LGRK 141
Query: 168 ANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGH 227
AN +Y++DFG+AK++RD NT +HIPYRE K+L+GTARY S NTH G EQ RRDDLESLG+
Sbjct: 142 ANQVYLIDFGLAKRYRDANTNRHIPYRENKNLTGTARYASCNTHLGIEQGRRDDLESLGY 201
Query: 228 VFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRF 287
V YFLRGSLPWQGLKA++ K KY+KI K+ P ++L P +FA Y YC +L F
Sbjct: 202 VLLYFLRGSLPWQGLKAVDKKQKYDKI-CEKKISTPIEVLCKSHPVEFASYFHYCHTLTF 260
Query: 288 DQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
DQ PDY +L L + GYE D YDW
Sbjct: 261 DQRPDYGFLKRLFRDLFSREGYEFDYIYDW 290
>YPL204w [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 494
Score = 265 bits (678), Expect = 8e-71
Identities = 141/308 (45%), Positives = 188/308 (60%), Gaps = 22/308 (7%)
Query: 10 VGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILND 69
VG + +G K ++G VAIK E RS PQL E R YR L+
Sbjct: 5 VGRKFRIGRKIGSGSFGDIYHGTNLISG---EEVAIKLESIRSRHPQLDYESRVYRYLSG 61
Query: 70 VRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHE 129
GIP +F +EG +N ++IDLLGPSLEDLF +C R+FS KT MLA QM R++ IH
Sbjct: 62 GVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHG 121
Query: 130 HDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQ 189
I+RDIKPDNFL+ +R + ++V+DFG++K++RD NT +
Sbjct: 122 RSFIHRDIKPDNFLMGVGRR------------------GSTVHVIDFGLSKKYRDFNTHR 163
Query: 190 HIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKA 249
HIPYRE KSL+GTARY S+NTH G EQSRRDDLESLG+V YF +GSLPWQGLKA K
Sbjct: 164 HIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQ 223
Query: 250 KYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGY 309
KY++I + K+ + L +P +F EY++YC++L+FD+ PDY +L L + + Y
Sbjct: 224 KYDRI-MEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEY 282
Query: 310 EEDGHYDW 317
D +DW
Sbjct: 283 HNDHLFDW 290
>CE05879 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 578
Score = 265 bits (676), Expect = 1e-70
Identities = 141/289 (48%), Positives = 183/289 (62%), Gaps = 20/289 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VA+K E +S PQL E R YRI+ GIP + QEG +N+++++LLGPSLEDLF
Sbjct: 214 VAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFN 273
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+C RKFS+KT +LA QM+ RV IH D I+RDIKPDNFL+
Sbjct: 274 FCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLM------------------ 315
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G NL+Y++DFG+AK++RD + QHI YRE K+L+GTARY SINTH G EQSRRDD+
Sbjct: 316 GLGKRGNLVYIIDFGLAKRYRD-SKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDI 374
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG+VF YF RG+LPWQGLKA+ + KYE I K + DL P+ FA+YL+YC
Sbjct: 375 ESLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCA-GYPEAFAQYLNYC 433
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQGWNIKVN 331
RSL F++ PDY YL +L + + D +DW N N+ +N
Sbjct: 434 RSLGFEEQPDYGYLRNLFRTLFHRQQFCYDYVFDWNTYNKRYQINVDIN 482
>CE00872 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 341
Score = 264 bits (674), Expect = 2e-70
Identities = 137/283 (48%), Positives = 178/283 (62%), Gaps = 19/283 (6%)
Query: 35 LNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLG 94
+N + VAIK E R+ PQL E + YRIL GIPH ++ E +N+L++DLLG
Sbjct: 34 INVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLG 93
Query: 95 PSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
PSLEDLF +CSR+F++KT MLA QMI R+ +H + I+RDIKPDNFL+
Sbjct: 94 PSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMG--------- 144
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
G N ++++DFG+AK++RD T+ HIPYRE K+L+GTARY SIN H G
Sbjct: 145 ---------IGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGI 195
Query: 215 EQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQ 274
EQSRRDD+ESLG+V YF RG+LPWQGLKA K KYEKI K+ + L P +
Sbjct: 196 EQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKIS-EKKMTTSVEHLCKGFPAE 254
Query: 275 FAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
F YLSY R LRFD+ PDY YL L + + ++ D +DW
Sbjct: 255 FPMYLSYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDW 297
>7302004 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 440
Score = 262 bits (669), Expect = 9e-70
Identities = 135/281 (48%), Positives = 176/281 (62%), Gaps = 19/281 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E R+ PQL E + Y+ + GIP + EG +N+++++LLGPSLEDLF
Sbjct: 35 VAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFN 94
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+CSR+FS+KT +LA QMI R+ IH D I+RDIKPDNFL+
Sbjct: 95 FCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMG----------------- 137
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G NL+Y++DFG+AK+FRD + +HIPYRE K+L+GTARY SINTH G EQSRRDDL
Sbjct: 138 -LGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ESLG+V YF G+LPWQGLKA N + KYE+I K+ +L P +F YL++C
Sbjct: 197 ESLGYVLMYFNLGALPWQGLKAANKRQKYERIS-EKKLSTSIVVLCKGFPSEFVNYLNFC 255
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGG 323
R + FDQ PDY +L L + G+ D +DW L G
Sbjct: 256 RQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFG 296
>SPAC23C4.12 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 400
Score = 254 bits (648), Expect = 3e-67
Identities = 134/311 (43%), Positives = 184/311 (59%), Gaps = 24/311 (7%)
Query: 10 VGIHYAVGPKXXXXXXXXXXXXXXXLNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILND 69
+G Y +G K +NG VA+K EP ++ QL EFR Y IL
Sbjct: 8 IGNKYRIGRKIGSGSFGQIYLGLNTVNG---EQVAVKLEPLKARHHQLEYEFRVYNILKG 64
Query: 70 VRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHE 129
GIP +F +N +++DLLGPSLEDLF +C RKF++KT +LA Q+I R+ +H
Sbjct: 65 NIGIPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTVLLLADQLISRIEYVHS 124
Query: 130 HDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQ 189
++RDIKPDNFL+ + +N++ ++DFG+AK++RD T
Sbjct: 125 KSFLHRDIKPDNFLMKKH--------------------SNVVTMIDFGLAKKYRDFKTHV 164
Query: 190 HIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKA 249
HIPYR+ K+L+GTARY SINTH G EQSRRDDLESLG+V YF RGSLPWQGL+A +
Sbjct: 165 HIPYRDNKNLTGTARYASINTHIGIEQSRRDDLESLGYVLLYFCRGSLPWQGLQADTKEQ 224
Query: 250 KYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGY 309
KY++I TK P ++L +P++F Y+ Y R L F + P+Y YL L ++ GY
Sbjct: 225 KYQRIRDTKIG-TPLEVLCKGLPEEFITYMCYTRQLSFTEKPNYAYLRKLFRDLLIRKGY 283
Query: 310 EEDGHYDWMDL 320
+ D +DWM L
Sbjct: 284 QYDYVFDWMIL 294
>7292798 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 337
Score = 253 bits (646), Expect = 4e-67
Identities = 134/279 (48%), Positives = 174/279 (62%), Gaps = 19/279 (6%)
Query: 39 SKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLE 98
S VAIK E + PQL E + YRIL+ G P + +E N L++DLLGPSLE
Sbjct: 42 SGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLE 101
Query: 99 DLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
DLF +C+R F++KT ML QMI R+ IH I+RDIKPDNFL+
Sbjct: 102 DLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMG------------- 148
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
G N ++++DFG+AK+FRDP+T+ HI YRE K+L+GTARY SIN H G EQSR
Sbjct: 149 -----IGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSR 203
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEY 278
RDD+ESLG+V YF RG LPWQG+KA + KYEKI K+ P ++L P +F+ Y
Sbjct: 204 RDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKIS-EKKMSTPIEVLCKGSPAEFSMY 262
Query: 279 LSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
L+YCRSLRF++ PDY YL L + + ++ D YDW
Sbjct: 263 LNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDW 301
>7296752 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 477
Score = 224 bits (570), Expect = 3e-58
Identities = 121/278 (43%), Positives = 162/278 (57%), Gaps = 20/278 (7%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E P L E R Y IL GIPH +++ EG +N++++DLLGP+LEDL
Sbjct: 94 VAIKLESSTVKHPLLPREARIYGILQGGLGIPHVKHYATEGAYNVMVMDLLGPTLEDLLN 153
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
CSR FS+KTT MLA Q++ RV +H I+RDIKPDNFL+ + +
Sbjct: 154 LCSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKPDNFLMGLNRHQTQ---------- 203
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
+Y++DFG+AK+F T++HI Y E + L GTARY S+ H+ EQSRRDDL
Sbjct: 204 --------VYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVRAHYA-EQSRRDDL 254
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ES+G++ YF RG LPWQG++A + KYEKI K + P L +P +F YL YC
Sbjct: 255 ESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANI-PLQQLCSGLPVEFFMYLKYC 313
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDL 320
R L F + PDY YL L + + D +DW+ L
Sbjct: 314 RKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVL 351
>7292762 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 344
Score = 218 bits (554), Expect = 2e-56
Identities = 113/275 (41%), Positives = 159/275 (57%), Gaps = 19/275 (6%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E + PQL E R YR L G+P YF +E + +++DLLGPSLE LF+
Sbjct: 43 VAIKVESSKVRHPQLNYERRIYRALRPAHGLPRIRYFHKEEHYQAMVMDLLGPSLERLFQ 102
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
+C R F++KT +LA+QM+ RV +H ++RDIKPDNFL+
Sbjct: 103 FCERAFTIKTVLLLAEQMLRRVEYVHNRGFLHRDIKPDNFLMG----------------- 145
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
G + +Y++DFG++K++ D T HIPYRE +SL+GTARY SI H G E +RRDD+
Sbjct: 146 -LGTMSKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAHAGVESARRDDM 204
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
++G+V YF RGSLPWQ LKA + KYE+I K + ++L P +F YL+YC
Sbjct: 205 VAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVS-IEVLCEGFPCEFTMYLNYC 263
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
R + F P+YD++ + + YDW
Sbjct: 264 RGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDW 298
>At4g08800 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 285
Score = 209 bits (532), Expect = 7e-54
Identities = 120/279 (43%), Positives = 155/279 (55%), Gaps = 51/279 (18%)
Query: 39 SKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLE 98
S VAIKFE ++ PQL E R YR+L GIP+ ++
Sbjct: 31 SNEDVAIKFESVKTVHPQLAYESRIYRVLQSGNGIPNMKWYG------------------ 72
Query: 99 DLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
KFS+KT MLA QMI+R+ IH ++RDIKPDNFL+ G K
Sbjct: 73 --------KFSLKTVLMLADQMINRLEFIHSKSFLHRDIKPDNFLM---------GKAGK 115
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
S DFG+A+++RD ++ +HIPYRE KSL+GT Y S+NTH G EQSR
Sbjct: 116 S---------------DFGLARKYRDSSSYRHIPYRENKSLTGTPAYASLNTHLGIEQSR 160
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEY 278
RDD+ESLG++ YFL+GSLPW+GLKA N K KY+KI K+ + L P +FA Y
Sbjct: 161 RDDVESLGYILMYFLKGSLPWKGLKAGNKKQKYDKIS-EKKVSTSIETLCEGHPIEFATY 219
Query: 279 LSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ YCRSLRFD PDY YL L + G++ D +DW
Sbjct: 220 IHYCRSLRFDDKPDYAYLKRLFRDLFIREGFQFDFVFDW 258
>ECU03g0910 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 327
Score = 205 bits (522), Expect = 1e-52
Identities = 110/287 (38%), Positives = 169/287 (58%), Gaps = 27/287 (9%)
Query: 36 NGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNI----LIID 91
N + VA+K E +++ QL+ E+ Y+ L R P Y + + N+ L+++
Sbjct: 50 NTVTNQTVAVKLE-KKAHYGQLKHEYGVYKALGGTR-TPRIYEYGKILYENVYVNGLVME 107
Query: 92 LLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQREL 151
L+G SLE LF CSR+FS+KT ML ++M+D V +H + ++RDIKPDNF+
Sbjct: 108 LMGKSLEQLFVTCSRRFSLKTVLMLGERMVDNVEYLHHRNYVHRDIKPDNFVFDV----- 162
Query: 152 SDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTH 211
+ +Y++D+G+AK+FR+P T +H R KSL+GTARY S+ TH
Sbjct: 163 ---------------QGDRLYLIDYGLAKEFRNPMTFKHREMRTDKSLTGTARYASLRTH 207
Query: 212 FGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEI 271
G EQSRRDDLES+G YFL+G LPWQGLKA + KY++I +K+ + +L +
Sbjct: 208 QGYEQSRRDDLESVGFCMVYFLKGRLPWQGLKAKTKQEKYDRIRESKESISLYELCM-GL 266
Query: 272 PKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWM 318
PK+ + Y R+L ++ P+Y YL +L++ +++ G DG +DWM
Sbjct: 267 PKEIHSFCFYVRNLGYEDMPNYAYLRTLLSDALRQRGLRSDGVFDWM 313
>7295933 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 319
Score = 194 bits (494), Expect = 2e-49
Identities = 107/280 (38%), Positives = 152/280 (54%), Gaps = 19/280 (6%)
Query: 38 GSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSL 97
GS VA+K E + + L E Y +L GIP Y F H++L+++LLGPSL
Sbjct: 36 GSGLHVALKVERKNAGQSHLSIESTVYNLLRHGMGIPMTYQFFSNRRHDVLVMELLGPSL 95
Query: 98 EDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVV 157
E LF C+R+FS+KT MLA QM+DR+ +H H ++RDIKP+NFL+
Sbjct: 96 ETLFTMCNRRFSMKTVLMLADQMVDRLEYLHLHHYVHRDIKPENFLM------------- 142
Query: 158 KSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQS 217
G + ++++DFG++K++ D +H+P R +GTARY S+N + QS
Sbjct: 143 -----GVGLTRHRLHLIDFGLSKRYWDMKENRHVPQRRGTKWAGTARYASVNALCCKVQS 197
Query: 218 RRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAE 277
RRDDLES+G+V Y LRGSLPWQGL + K E I K P L P +F
Sbjct: 198 RRDDLESVGYVLIYLLRGSLPWQGLLPNSKLQKAEMILEMKLSTLPNSLCA-GYPNEFYN 256
Query: 278 YLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
Y+ Y R L F+++PDY + ++ + D YDW
Sbjct: 257 YIIYTRQLGFEEEPDYRMIRCTFLSLLFNLKFTNDLIYDW 296
>7298405 [T] KOG1163 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 367
Score = 165 bits (418), Expect = 1e-40
Identities = 96/278 (34%), Positives = 139/278 (49%), Gaps = 42/278 (15%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E + PQL E + Y L G P ++
Sbjct: 53 VAIKVEKNDAKYPQLIYEAKVYEQLARCPGFPTLLHYG---------------------- 90
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCAT 162
C + ++ T ML Q++ R+ +HE I+RDIKPDNFL+ + + C
Sbjct: 91 -CEKNYNAMTVLMLTDQLLMRIECVHERGFIHRDIKPDNFLMG----------LDRHC-- 137
Query: 163 SSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDL 222
N +Y++DFG++K+++D ++ HIPYR ++L+GT RY SIN G EQSRRDD+
Sbjct: 138 ------NKLYLIDFGLSKRYKDIESEIHIPYRTDRNLTGTVRYASINAQIGVEQSRRDDM 191
Query: 223 ESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYC 282
ES+ + YF G LPWQG+ A N K KYEKI L K+ L P +F ++Y
Sbjct: 192 ESMSYCLMYFNLGKLPWQGITAANKKQKYEKI-LEKKTSVTIAQLCKGFPSEFCLLMTYV 250
Query: 283 RSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDL 320
R+L F + PD+ YL + + + + D YDW L
Sbjct: 251 RNLGFKEPPDHTYLRQIFRILFRSLNHHYDYIYDWTAL 288
>At3g13670 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 703
Score = 147 bits (372), Expect = 3e-35
Identities = 84/274 (30%), Positives = 140/274 (50%), Gaps = 23/274 (8%)
Query: 37 GGSKNPVAIKFEPRRSDSPQLRD--EFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLG 94
G S VA+KFE R S E++ Y L G+P ++ ++G + ++++D+LG
Sbjct: 166 GASILEVALKFEHRSSKGCNYGPPHEWQVYNTLGGSHGVPRVHFKGRQGDYYVMVMDMLG 225
Query: 95 PSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
PSL DL+ + S + A +A + + + +H ++ D+KP+NFL+ +
Sbjct: 226 PSLWDLWNTSGQAMSSEMVACIAVESLSILEKMHAKGYVHGDVKPENFLLGQ-------- 277
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSL-SGTARYMSINTHFG 213
S +++VD G+A ++R+ + QH+ Y +R + GT RY S + H G
Sbjct: 278 --------PSTSQEKKLFLVDLGLATKWREGGSGQHVEYDQRPDMFRGTVRYASAHAHLG 329
Query: 214 REQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPK 273
R SRRDDLESL + + RG LPWQG + N K K+ D+L P
Sbjct: 330 RTASRRDDLESLAYTLIFLHRGRLPWQGYQGDNKSFLVCK----KKMATSPDMLCCFCPP 385
Query: 274 QFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQEN 307
F ++L +++FD++P+Y L+SL ++ EN
Sbjct: 386 PFKQFLEIVVNMKFDEEPNYGKLVSLFQDLLGEN 419
>At2g25760 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 304
Score = 147 bits (371), Expect = 3e-35
Identities = 84/268 (31%), Positives = 139/268 (51%), Gaps = 20/268 (7%)
Query: 43 VAIKFEPRRSDSPQLRD--EFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDL 100
VA+KFE R S E++ Y L G+P ++ ++G ++++D+LGPSL D+
Sbjct: 38 VALKFEHRTSKGCNYGPPYEWQVYNALGGSHGVPRVHFKGRQGDFYVMVMDILGPSLWDV 97
Query: 101 FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSC 160
+ ++ S + A +A + I + +H ++ D+KP+NFL+
Sbjct: 98 WNSTTQAMSTEMVACIAIEAISILEKMHSRGYVHGDVKPENFLLGP-------------- 143
Query: 161 ATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSL-SGTARYMSINTHFGREQSRR 219
+ +++VD G+A ++RD T H+ Y +R + GT RY S++ H GR SRR
Sbjct: 144 --PGTPEEKKLFLVDLGLASKWRDTATGLHVEYDQRPDVFRGTVRYASVHAHLGRTCSRR 201
Query: 220 DDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYL 279
DDLESL + + LRG LPWQG + + K K + K P + L P+ F +++
Sbjct: 202 DDLESLAYTLVFLLRGRLPWQGYQVGDTKNKGFLVCKKKMATSP-ETLCCFCPQPFRQFV 260
Query: 280 SYCRSLRFDQDPDYDYLISLMTQIMQEN 307
Y +L+FD++PDY +SL I+ N
Sbjct: 261 EYVVNLKFDEEPDYAKYVSLFDGIVGPN 288
>At5g18190 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 691
Score = 147 bits (370), Expect = 4e-35
Identities = 83/273 (30%), Positives = 140/273 (50%), Gaps = 23/273 (8%)
Query: 37 GGSKNPVAIKFEPRRSDSPQLRD--EFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLG 94
G VA+KFE R S E++ Y LN G+P ++ ++G IL++D+LG
Sbjct: 158 GADAIEVALKFEHRNSKGCNFGPPYEWQVYNTLNGCYGVPAVHHKGRQGDFYILVMDMLG 217
Query: 95 PSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
PSL D++ + S A +A + I + +H ++ D+KP+NFL+ +
Sbjct: 218 PSLWDVWNSSGQSMSPNMVACIAVESISILEKLHMKGFVHGDVKPENFLLGQ-------- 269
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSL-SGTARYMSINTHFG 213
D +Y++D G+A +++D ++ QH+ Y +R + GT RY S++ H G
Sbjct: 270 --------PGTADEKKLYLIDLGLASKWKDSHSGQHVEYDQRPDVFRGTIRYASVHAHLG 321
Query: 214 REQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPK 273
R SRRDDLESL + + L+G LPWQG + N K K+ +L+ P
Sbjct: 322 RTGSRRDDLESLAYTLIFLLKGRLPWQGYQGDNKSFLVCK----KKMSTSPELMCCFCPP 377
Query: 274 QFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQE 306
F +L +++FD++P+Y LIS+ ++++
Sbjct: 378 PFKLFLEAVTNMKFDEEPNYAKLISIFDSLIEQ 410
>At3g03940 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 701
Score = 143 bits (361), Expect = 5e-34
Identities = 83/272 (30%), Positives = 138/272 (50%), Gaps = 23/272 (8%)
Query: 37 GGSKNPVAIKFEPRRSDSPQLRD--EFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLG 94
G VA+K E R S E++ Y LN GIP ++ ++G IL++D+LG
Sbjct: 168 GADAIEVALKLEHRNSKGCNFGPPYEWQVYNTLNSCYGIPAVHHKGRQGDFYILVMDMLG 227
Query: 95 PSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
PSL D++ ++ S A +A + I + +H ++ D+KP+NFL+ +
Sbjct: 228 PSLWDVWNSLAQSMSPNMVACIAVEAISILEKLHMKGFVHGDVKPENFLLGQ-------- 279
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSL-SGTARYMSINTHFG 213
D +Y++D G+A +++D ++ QH+ Y +R + GT RY S + H G
Sbjct: 280 --------PGTADEKKLYLIDLGLASRWKDSHSGQHVEYDQRPDVFRGTIRYASCHAHLG 331
Query: 214 REQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPK 273
R SRRDDLESL + + +RG LPWQG + N K K+ +L+ P
Sbjct: 332 RTGSRRDDLESLAYTLIFLMRGRLPWQGYQGDNKSFLVCK----KKMSTSPELMCCFCPP 387
Query: 274 QFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQ 305
F +L +++FD++P+Y LIS+ +++
Sbjct: 388 PFKLFLEAVTNMKFDEEPNYAKLISIFDTLIE 419
>Hs20555151 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 1270
Score = 120 bits (302), Expect = 3e-27
Identities = 84/283 (29%), Positives = 137/283 (47%), Gaps = 32/283 (11%)
Query: 39 SKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIH---NILIIDLLGP 95
++ VA+K E + L+ E +L ++G H F G + N +++ L G
Sbjct: 5 TRENVALKVESAQQPKQVLKMEVA---VLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGR 61
Query: 96 SLEDLFEWCSR-KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
+L DL R F++ TT L KQ+++ + +IH ++RDIKP NF +
Sbjct: 62 NLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLP------ 115
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
S + C Y++DFG+A+Q+ + T P R GT RY S+N H R
Sbjct: 116 STYRKC-----------YMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYASVNAHKNR 163
Query: 215 EQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQ 274
E R DDL SL ++ F G LPW+ +K E++G+ K++ + +L +P +
Sbjct: 164 EMGRHDDLWSLFYMLVEFAVGQLPWRKIK------DKEQVGMIKEKYEHR-MLLKHMPSE 216
Query: 275 FAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
F +L + SL + PDY ++S+ M+E G E+ +DW
Sbjct: 217 FHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 259
>ECU11g1980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 318
Score = 120 bits (302), Expect = 3e-27
Identities = 86/251 (34%), Positives = 126/251 (49%), Gaps = 25/251 (9%)
Query: 59 DEFRAYRILNDVRGIPHAY-YFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLA 117
+E +AY L IP + S EG+ L++ LL SL+DL E R F+ K+ ++
Sbjct: 52 NEIQAYSELQGCEKIPRLVDHGSYEGL-TFLVLPLLKYSLKDLLERHPRFFTKKSATIVG 110
Query: 118 KQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFG 177
K++++ + IH ++RDIKP+N + G N IY+VDFG
Sbjct: 111 KKLLNAIEFIHGKGRLHRDIKPENVMF---------------------GHNNRIYLVDFG 149
Query: 178 MAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSL 237
M+ + + HIP KS+SGT YMSINTH G EQSRRDDLESL ++ + L
Sbjct: 150 MSAPYLRGDGS-HIPEVGGKSVSGTLWYMSINTHRGIEQSRRDDLESLFYLLILLYKSRL 208
Query: 238 PWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQ-FAEYLSYCRSLRFDQDPDYDYL 296
PW A +K + + K+ L DL K+ ++ + SL F + P+Y YL
Sbjct: 209 PWMEPGASVSKKQEARTKEIKENLSVYDLCDGIHGKEHLIKFFQHISSLEFAEKPNYRYL 268
Query: 297 ISLMTQIMQEN 307
SL+ +I N
Sbjct: 269 NSLLDKIFHSN 279
>CE06325 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 776
Score = 115 bits (289), Expect = 1e-25
Identities = 76/276 (27%), Positives = 132/276 (47%), Gaps = 26/276 (9%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
VAIK E ++ L+ E R L + Y + N L++ L G +L DL
Sbjct: 47 VAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRR 106
Query: 103 WCSRK-FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCA 161
++ F++ T + Q+++ +R IH ++RD+KP NF + + + +
Sbjct: 107 EAPKQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRN-------- 158
Query: 162 TSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDD 221
+Y++DFG+A+Q+ + + P R GT RY ++ H +E R+DD
Sbjct: 159 ---------VYMLDFGLARQYLNAKGEIRSP-RSAAGFRGTVRYAAVTAHKNKEMGRQDD 208
Query: 222 LESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSY 281
L SL ++ FL+G LPW+ +K +++G K+ LL + P + ++++
Sbjct: 209 LWSLFYMLTEFLQGQLPWRKIK------DKDEVGKMKEEADLVVLL-DDCPHEMHLFVAH 261
Query: 282 CRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ L + PDY YL SL+ +I+ EN D YDW
Sbjct: 262 LKVLGYADTPDYVYLESLLNKIVAENEISWDEPYDW 297
>CE01289 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 263
Score = 103 bits (256), Expect = 7e-22
Identities = 70/236 (29%), Positives = 117/236 (48%), Gaps = 31/236 (13%)
Query: 86 NILIIDLLGPSLEDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N LI+ L+G +L +L C +RKFS +T + QMI+ ++ +H I+RDIKP NF I
Sbjct: 30 NFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCI 89
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF-RDPNTKQHIPYRERKSLSGTA 203
+ + + + +VDFGM +++ D T+ P GT
Sbjct: 90 NL-------------------DNPHQLVMVDFGMCRKYLNDGGTQLRHPRWSVHGFRGTV 130
Query: 204 RYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP 263
RY + TH+GR+ R++DLE++ +V L G+LPW ++ ++ + +KQ +
Sbjct: 131 RYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTME------EHIHVEHSKQVART 184
Query: 264 TDL--LTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
T L PKQ L Y +LRF PDY + L++ ++ + +G ++W
Sbjct: 185 TGLREFLSGCPKQLVHILLYIDNLRFYDAPDYALIRGLLSFALE--NCQHNGSFEW 238
>CE28799 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 379
Score = 102 bits (254), Expect = 1e-21
Identities = 77/281 (27%), Positives = 128/281 (45%), Gaps = 27/281 (9%)
Query: 44 AIKFEPRRSDS-PQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
A+K E + +S P L+ + +RG P+ + ++ I+ L+GP L L
Sbjct: 53 AMKCERQEGNSRPVLKLDVMVLMATKGLRGFPNFVAAGRTDVYRYCIMQLVGPDLGRLRR 112
Query: 103 WC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCA 161
RKFS+ T + Q + R+ +H + RD+K NF I + E
Sbjct: 113 TRPERKFSLPTALQILGQTLRRLEDLHNCGWLCRDVKAPNFCIGVGENE----------- 161
Query: 162 TSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDD 221
+ +Y++DFG A++F D K IP R +L GT +Y +++ H ++Q RDD
Sbjct: 162 -------STVYILDFGFARKFVDKEGKI-IPPRTAAALMGTFQYCAVSAHSHKDQCARDD 213
Query: 222 LESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLT---PEIPKQFAEY 278
LES ++ L+G LPW + N +++IG K ++ L + +PKQF E
Sbjct: 214 LESWFYMGIELLKGPLPWANIDGHKN---HKQIGEAKVAIRSEPLRSEFFEGVPKQFNEI 270
Query: 279 LSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMD 319
L+ + P+Y L L++Q E+ DW +
Sbjct: 271 LTILDQTSYFDRPNYKKLGDLLSQAATEHQVTLKEPLDWQN 311
>Hs4507903 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 396
Score = 99.8 bits (247), Expect = 8e-21
Identities = 81/309 (26%), Positives = 140/309 (45%), Gaps = 47/309 (15%)
Query: 38 GSKNPVAIKFEPRRSDSPQLRDEFRAYR-------ILNDVR-------GIPHAYYFSQEG 83
GS P +K EP SD+ L E + Y+ I +R G+P Y+ S G
Sbjct: 63 GSDAPCVVKVEP--SDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPK-YWGS--G 117
Query: 84 IHN-------ILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRD 136
+H+ +I+D G L+ ++E +++FS KT L+ +++D + IHEH+ ++ D
Sbjct: 118 LHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGD 177
Query: 137 IKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRER 196
IK N L++ + + +Y+VD+G+A ++ + +
Sbjct: 178 IKASNLLLNY-------------------KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPK 218
Query: 197 KSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGL 256
+ GT + SI+ H G SRR DLE LG+ +L G LPW+ + KI
Sbjct: 219 RCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
Query: 257 TKQRLKPTDLLTPE--IPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGH 314
+ D PE P + A+Y+ + L + + P Y+ L ++ Q ++ G ++DG
Sbjct: 279 RENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGK 338
Query: 315 YDWMDLNGG 323
D + G
Sbjct: 339 LDLSVVENG 347
>CE29490 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 422
Score = 99.0 bits (245), Expect = 1e-20
Identities = 72/260 (27%), Positives = 120/260 (45%), Gaps = 31/260 (11%)
Query: 66 ILNDVRGIPHAYYF---SQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMID 122
IL + G PH F ++ +I+ LLG SL + + +R+ +V + +A ++
Sbjct: 71 ILKKLSGKPHVCQFLFAARLTDFTYVIMTLLGESLNKIVKRIARQITVSSQVRIAANVLF 130
Query: 123 RVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF 182
++ IH+ I+RD+KP N + ++ + +V+DFG+A+QF
Sbjct: 131 CLKQIHDIGFIHRDLKPANMALGY---------------KTNNDECRFFHVLDFGLARQF 175
Query: 183 -----RDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSL 237
P+ RER GT RY SI H EQ R DDL S+ ++ LRG L
Sbjct: 176 VVSQSDQPSKLMMRRPRERSLFRGTTRYCSIRMHDRAEQGRVDDLWSMVYLLAE-LRGPL 234
Query: 238 PWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLI 297
PW ++++ +G K RL +++ P +F E Y RSL + PDY +
Sbjct: 235 PW------SSQSDKRVVGEMK-RLHSDEVVLQNSPMEFLEIAKYLRSLTYFHRPDYHKIF 287
Query: 298 SLMTQIMQENGYEEDGHYDW 317
L+ +M + + + +DW
Sbjct: 288 MLLISVMSKGKFAWNDPFDW 307
>CE01965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 424
Score = 99.0 bits (245), Expect = 1e-20
Identities = 73/260 (28%), Positives = 120/260 (46%), Gaps = 31/260 (11%)
Query: 66 ILNDVRGIPHAYYF---SQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMID 122
IL + G PH F ++ +I+ LLG SL + + +R+ +V + +A ++
Sbjct: 78 ILKKLSGKPHVCQFLFAARLTDFTYVIMTLLGESLNKIVKRIARQITVSSQVRIAANVLF 137
Query: 123 RVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF 182
++ IH+ I+RD+KP N + ++ + +V+DFG+A+QF
Sbjct: 138 CLKQIHDIGFIHRDLKPANMALGY---------------KTNNDECRFFHVLDFGLARQF 182
Query: 183 -----RDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSL 237
P+ RER GT RY SI H EQ R DDL S+ ++ LRG L
Sbjct: 183 VVSQSDQPSKLMMRRPRERSLFRGTTRYCSIRMHDRAEQGRVDDLWSILYLLAE-LRGPL 241
Query: 238 PWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLI 297
PW + N+K ++ +RL +++ P +F E Y RSL + PDY +
Sbjct: 242 PWS---SQNDKRVVGEM----KRLHSDEVVLQNSPMEFLEIAKYLRSLTYFHRPDYHKIF 294
Query: 298 SLMTQIMQENGYEEDGHYDW 317
L+ IM + + + +DW
Sbjct: 295 MLLISIMSKGKFSWNDPFDW 314
>CE02142 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 471
Score = 98.2 bits (243), Expect = 2e-20
Identities = 71/234 (30%), Positives = 104/234 (44%), Gaps = 29/234 (12%)
Query: 86 NILIIDLLGPSLEDLFEWCSRK-FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N +++ L+GPSL DL + K F++ TTA+ A Q D + I I+RD+KP NF I
Sbjct: 97 NYIVMHLVGPSLSDLRKTVPNKTFTLFTTAVCAIQCFDSLVEIQRIGYIHRDVKPSNFAI 156
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTAR 204
E + L+YV+DFG+ + + + P R + GT
Sbjct: 157 GVLGSE----------------EEKLVYVLDFGLCRNMFNKQKELRKP-RMKAPFRGTIL 199
Query: 205 YMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGL-KALNNKAKYEKIGLTKQRLKP 263
Y S+N H E R DD SL ++ F LPW+ + K KAK K+
Sbjct: 200 YCSLNIHQRMEPGRHDDFWSLLYMMIEFHLSDLPWENMSKEDTKKAKETKL--------- 250
Query: 264 TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
D L P +F Y +L + ++PDY L ++ QIM + D DW
Sbjct: 251 -DGLLARCPPEFRMIRCYLLTLTYSKEPDYVKLREVLCQIMTSKKFTPDMPLDW 303
>CE06632 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 305
Score = 97.8 bits (242), Expect = 3e-20
Identities = 67/235 (28%), Positives = 110/235 (46%), Gaps = 27/235 (11%)
Query: 86 NILIIDLLGPSLEDLFEWCS-RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N +++ L+G SL+DL + KFS+ T +A+Q ++ V +H ++RDIKP N+ I
Sbjct: 94 NYMVMTLVGKSLQDLRKTAPFNKFSMGTAISVARQSLEAVEDLHNIGFLHRDIKPGNYTI 153
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTAR 204
+ + +Y++DFGMA++F + P R R GT +
Sbjct: 154 GRKEMH----------------ELRKVYMLDFGMARKFAREDGTLRNP-RARAGFRGTVK 196
Query: 205 YMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPT 264
Y + H REQ R+DD+ES ++ G LPW+ N + + +G+ K+ K T
Sbjct: 197 YAPLACHIQREQCRKDDIESWLYMVVEMTCGRLPWR------NLTESDDVGVFKKECKTT 250
Query: 265 DL--LTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
L L P++F E +F P+Y + L+ + M N + YDW
Sbjct: 251 RLRCLFGGCPREFTEVFPILDKGKFFDAPEYTTIYELLEKAM-VNTKSNEFPYDW 304
>7304307 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 936
Score = 97.8 bits (242), Expect = 3e-20
Identities = 57/173 (32%), Positives = 86/173 (48%), Gaps = 16/173 (9%)
Query: 171 IYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFF 230
+Y++DFG+A+Q+ + P R GT RY SIN H RE R DDL SL ++
Sbjct: 353 VYMLDFGLARQYTTGTGEVRCP-RAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLV 411
Query: 231 YFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQD 290
F+ G LPW+ +K E++GLTK++ +L +P ++L + +SL +
Sbjct: 412 EFVNGQLPWRKIK------DKEQVGLTKEKYDHR-ILLKHLPSDLKQFLEHIQSLTYGDR 464
Query: 291 PDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQGWNIKVNKRVNLHGYGNPT 343
PDY LI L + M+ G +E YDW ++ NI GNP+
Sbjct: 465 PDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISAT--------GNPS 509
>CE16557 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 318
Score = 97.1 bits (240), Expect = 5e-20
Identities = 80/285 (28%), Positives = 136/285 (47%), Gaps = 36/285 (12%)
Query: 39 SKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLE 98
+K VA+K EP+ +S ++ E L IP +Y + G +N +++ LLG ++
Sbjct: 60 TKLVVAVKVEPKSVESGRIVLELHILVELAHSPHIPKVHYSGEIGGYNFIVMQLLGSNIT 119
Query: 99 DLFEWCS-RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVV 157
DL ++ R FS +TTA + Q ++ ++ IHE I+RDIKP N +
Sbjct: 120 DLRKFQKGRCFSAETTARVGIQCLEGLKQIHELGYIHRDIKPSNICV------------- 166
Query: 158 KSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQS 217
G ++Y+VDFGMA+Q R P+ P R S GT RY+S+ H +EQ
Sbjct: 167 -----GIGEHKRVLYIVDFGMARQIRFPSGAFR-PERPYASFRGTTRYVSLAAHERKEQG 220
Query: 218 RRDDLESLGHVFFYFLR--GSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQF 275
DD+ L FF L LPW+ N +++ KQ L + + ++ + F
Sbjct: 221 FADDIWCL---FFSLLELAEGLPWK------NVVDQDQVYHAKQLLL-RNFQSRKMGQNF 270
Query: 276 AEYLSYCRSLRFDQDPDYD-YLISLMTQIMQENGYEEDGHYDWMD 319
+ ++ + P+Y+ +++ L + + N +EE ++W D
Sbjct: 271 GTFPRALELIKRTETPNYENFIVILKSCSSRVNEWEE---FEWDD 312
>CE14562 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 488
Score = 95.5 bits (236), Expect = 2e-19
Identities = 74/279 (26%), Positives = 127/279 (44%), Gaps = 46/279 (16%)
Query: 53 DSPQLRDEFRAYRILNDVRGIPHAYYFSQEGI---HNILIIDLLGPSLEDLFEWC-SRKF 108
+ P L E + LN+ I H +G + +++ LLGPSL+ + + KF
Sbjct: 56 EDPTLPMEHKIISKLNEKNSI-HCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKF 114
Query: 109 SVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDA 168
S +T ++ Q +D ++ IH+ ++RD+KP NF I
Sbjct: 115 STFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQ---------------- 158
Query: 169 NLIYVVDFGMAKQF----------RDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
L++V+DFG+++Q+ R ++ +P+R GT RY S+ +EQ R
Sbjct: 159 RLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFR------GTLRYCSVAAQERKEQGR 212
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEY 278
DDL SL ++ F++GSLPW G+ + EK+ + K+ + T+L + + A +
Sbjct: 213 HDDLWSLFYMIVEFVKGSLPWTGI------MEEEKVIVMKEDV--TELFN-GLESECAMF 263
Query: 279 LSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ LR+ +PDY L L+ I + DW
Sbjct: 264 AQHLSVLRYQTNPDYALLRDLLMNIFVRRNFNAQMKVDW 302
>CE06942 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 308
Score = 95.1 bits (235), Expect = 2e-19
Identities = 64/244 (26%), Positives = 116/244 (47%), Gaps = 28/244 (11%)
Query: 83 GIHNILIIDLLGPSLEDLFE-WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDN 141
G N +++ L+G SL+DL + S+ + + Q ++ + +H ++RD+KP N
Sbjct: 83 GNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRDVKPGN 142
Query: 142 FLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSG 201
+ I + EL++ +Y++DFGM ++F + P R+ G
Sbjct: 143 YTIG--RPELNE--------------IRKVYILDFGMCRKFTGNDGTIRKP-RQAAGFRG 185
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
T +Y I+ H RE R+DDLE+ ++ G++PWQ + +N ++G KQ +
Sbjct: 186 TVKYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQHISDMN------QVGQAKQAI 239
Query: 262 KPT--DLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMD 319
+ L P P+QF + + ++++ P+Y + +M Q G E+ YDW
Sbjct: 240 RNNLGTLFPPPCPQQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE- 298
Query: 320 LNGG 323
NGG
Sbjct: 299 -NGG 301
>CE18365 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 308
Score = 94.4 bits (233), Expect = 3e-19
Identities = 64/244 (26%), Positives = 115/244 (46%), Gaps = 28/244 (11%)
Query: 83 GIHNILIIDLLGPSLEDLFE-WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDN 141
G N +++ L+G SL+DL + S+ + + Q ++ + +H ++RD+KP N
Sbjct: 83 GNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRDVKPGN 142
Query: 142 FLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSG 201
+ I + EL++ +Y++DFGM ++F + P R+ G
Sbjct: 143 YTIG--RPELNE--------------IRKVYILDFGMCRKFTGNDGTIRKP-RQAAGFRG 185
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
T +Y I+ H RE R+DDLE+ ++ G++PWQ + +N ++G KQ +
Sbjct: 186 TVKYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQYISDMN------QVGQAKQAI 239
Query: 262 KPT--DLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMD 319
+ L P P QF + + ++++ P+Y + +M Q G E+ YDW
Sbjct: 240 RNNLGSLFPPPCPHQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE- 298
Query: 320 LNGG 323
NGG
Sbjct: 299 -NGG 301
>CE02312 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 325
Score = 93.2 bits (230), Expect = 8e-19
Identities = 70/286 (24%), Positives = 130/286 (44%), Gaps = 34/286 (11%)
Query: 36 NGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRG---IPHAYYFSQEGIHNILIIDL 92
N ++ VA+K E ++ Q ++L+D+ G P+ YY +N +++ +
Sbjct: 65 NTETQEEVAVKVERATTNDSQRM--ILESKVLDDMLGSKHFPNVYYIGPYHSYNFIVMQM 122
Query: 93 LGPSLEDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQREL 151
LG ++ D+ + ++K S+ ++ + Q+I+ + +H ++RD+KP N
Sbjct: 123 LGKNIGDIRKMMPNKKISILSSVRIGIQIIEALSLLHSKGWLHRDLKPTN---------- 172
Query: 152 SDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTH 211
C +Y+VDFGM+++FR+ N R GT RY S H
Sbjct: 173 --------CCLGLDEKRKTVYLVDFGMSRKFRNDNGSLR-ESRTYCGFRGTTRYCSYRMH 223
Query: 212 FGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEI 271
REQ DDL L + + G LPW+ +++ + A +KI LK D+ +
Sbjct: 224 DRREQGPVDDLWCLYYSLGELIEGCLPWRDIESADEMAHVKKI------LKHEDIF-HSM 276
Query: 272 PKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
P +FA + R LR PDY +++ ++ +++ ++W
Sbjct: 277 PSKFASFGRNLRRLRPANTPDYTKFQNILAYCVK--FVDDNAEFEW 320
>CE27672 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 406
Score = 92.4 bits (228), Expect = 1e-18
Identities = 65/234 (27%), Positives = 108/234 (45%), Gaps = 22/234 (9%)
Query: 85 HNILIIDLLGPSLEDL-FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFL 143
+N +II +LG L L E +R F++ TT +A + I+ + +H + RD+KP NF
Sbjct: 155 YNYMIISILGKDLYRLRAEQPTRSFTLNTTTKIALETIEAIEELHNIGYLSRDVKPSNF- 213
Query: 144 ISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTA 203
+ QR+ G I++ DFG+AK+F D + K+ + R GT
Sbjct: 214 -APGQRD--------------NGQHKTIFMFDFGLAKKFIDRDNKK-LKSRGEVGWRGTV 257
Query: 204 RYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP 263
RY S+ H + RRDD+E ++ L G LPW+ + K+ + + +
Sbjct: 258 RYGSLQAHKRMDLGRRDDVECWFYMLIEMLVGELPWRHMSD-RTLVGQSKLSIRNESRR- 315
Query: 264 TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
L P+QF + F+ P+Y +L +L+ +I EN + +DW
Sbjct: 316 --LFFNRTPRQFETIMDMIDGYSFEIRPEYRHLKALINEIRMENMIPDRCKWDW 367
>CE22097 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 468
Score = 92.4 bits (228), Expect = 1e-18
Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 27/256 (10%)
Query: 67 LNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRS 126
L D R + + + ++ ++ L G L L R F+ T +A + ++
Sbjct: 77 LTDSRDVLKLIDYGKRKLYRYMVTTLCGKDLMALRMKIQRGFNDATAMRVAVFTLYGLKQ 136
Query: 127 IHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF---R 183
+HE ++RD+KP N + A + G DA ++ ++DFGMA+ F
Sbjct: 137 LHEAGYVHRDVKPGNIMT----------------AANKGRDARVMLLIDFGMARTFVMAG 180
Query: 184 DPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLK 243
D K+ P R R L GT RY S+N H +EQ R DDL ++ + Y G LPW LK
Sbjct: 181 DDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQGRCDDLVAMIYSIVYLTLG-LPWSNLK 239
Query: 244 ALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQI 303
EK ++ ++ L ++P + Y R+L + P+Y+ + +L+
Sbjct: 240 D-------EKEIMSMKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKIYNLLMAA 292
Query: 304 MQENGYEEDGHYDWMD 319
+ Y+W D
Sbjct: 293 ITRLKINFLDPYEWED 308
>CE05253 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 380
Score = 92.4 bits (228), Expect = 1e-18
Identities = 60/237 (25%), Positives = 115/237 (48%), Gaps = 29/237 (12%)
Query: 86 NILIIDLLGPSLEDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N +++ +G SL DL ++KFS+ T +A+Q ++ + +H ++RD+KP N+ I
Sbjct: 86 NYVVMTFVGLSLADLRAISPTKKFSMGTAISIARQSLEALEDMHNIGYLHRDVKPGNYTI 145
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTAR 204
+ + +YV+DFGMA++F + P R GT +
Sbjct: 146 GR----------------AEVNELRKVYVLDFGMARKFAHEDGTIKKP-RNVAGFRGTVK 188
Query: 205 YMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPT 264
Y ++ H GRE R+DD E+ ++ +GSLPW+ N + + +G K+ ++
Sbjct: 189 YAPVSCHAGRELCRQDDCETWLYMVVELTKGSLPWR------NMTEIQDVGNEKRAIRRD 242
Query: 265 DLLTPEI----PKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
++ ++ P+++ + L +F +P+Y+ + L+ + M+ G E YDW
Sbjct: 243 PIVKKKMFGGCPREYLDILEAIDKGQFFDEPNYERIYYLLREAMKNTGSTE-YPYDW 298
>CE08640 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 307
Score = 92.0 bits (227), Expect = 2e-18
Identities = 59/233 (25%), Positives = 113/233 (48%), Gaps = 37/233 (15%)
Query: 88 LIIDLLGPSLEDL-FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
+I+ LLG +L +L F + +FS+ T LA I ++S+H+ ++RDIK NF I++
Sbjct: 110 IIMPLLGENLMNLRFLFEDGRFSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIAD 169
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
Q + +K C ++D+G+ + F+D + + P + K GT RY
Sbjct: 170 PQMLHQNPEALKLC------------LIDYGICRSFKDKSGELKTPRTDIK-FRGTNRYA 216
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL 266
S+ H+G EQS +DD+ES ++ + G+LPW + ++ +++++
Sbjct: 217 SLAAHYGDEQSAKDDMESWFYMMIELISGNLPW----SFMHRDQHKEV------------ 260
Query: 267 LTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMD 319
+F +Y L++ DY ++ ++ M+ NG + +DW +
Sbjct: 261 -------EFHRIQAYLMGLKYQNTVDYTFISEMVQLAMRNNGVRMNEKFDWQE 306
>CE09021 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 278
Score = 89.7 bits (221), Expect = 8e-18
Identities = 62/217 (28%), Positives = 98/217 (44%), Gaps = 22/217 (10%)
Query: 88 LIIDLLGPSLEDL-FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
++I LLG L L E RKFS+ T + Q + +H + RD+KP NF
Sbjct: 82 MMITLLGKDLHKLRCELPGRKFSINTALRIGIQTLKACEELHRIGFVSRDVKPGNF---- 137
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
+ S + I++ DFG+A+++ D N Q IP R+ GT RY
Sbjct: 138 ------------APGVKSNRQSRTIFMYDFGLARKYIDKNN-QVIPTRKEVGWRGTTRYG 184
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL 266
S+N H + RRDDLES + RG+LPW+ + +++ ++ T
Sbjct: 185 SLNAHKRLDLGRRDDLESWFYGLVEMTRGTLPWRNVV---DRSSVQRAKEASHNTGRTQF 241
Query: 267 LTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQI 303
L E P Q+ + + S F+ PDY + L+ ++
Sbjct: 242 LF-ETPSQYDKIFTIVDSYAFESAPDYKQINKLLVEV 277
>CE03499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 361
Score = 89.0 bits (219), Expect = 1e-17
Identities = 77/302 (25%), Positives = 131/302 (42%), Gaps = 41/302 (13%)
Query: 40 KNPVAIKFEP--RRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSL 97
K A+K EP + + L+ E + L + R + + + +++ +LG +
Sbjct: 43 KGSAAMKVEPLMKNKEDEILKMEVYVLKKLQNSRHVCRLLGSGKTETYTYMVMSVLGKEI 102
Query: 98 EDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSV 156
D+ RK S +T + Q++ ++ +HE ++RD+KP N +
Sbjct: 103 GDVRRRLPQRKMSAPSTVRVFIQLVKALQDMHEAGFVHRDVKPSNMALG----------- 151
Query: 157 VKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLS---GTARYMSINTHFG 213
VK+ ++Y+ DFG+++Q P+ + RE ++ S GT RY S+N H
Sbjct: 152 VKN--------EQVVYIFDFGLSRQIMLPDASGKLKLREPRNKSMFRGTVRYCSLNVHLH 203
Query: 214 REQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL-LTPEIP 272
+EQ R DDL + +LPW+G K K E L + K TD+ L P
Sbjct: 204 KEQGRHDDLYGALYAMIETATSTLPWKG------KPKKETSALKE---KTTDVQLCKGCP 254
Query: 273 KQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQE--NGYEEDGHYDWMDLNGGQGWNIKV 330
K F E + R L + + P Y S M ++ + G + ++W +L G N
Sbjct: 255 KSFLEIATTLRKLTYKETPPYG---SFMEKLKADLPKGVKMTDPFEW-NLKGALDENNNG 310
Query: 331 NK 332
NK
Sbjct: 311 NK 312
>CE02210 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 361
Score = 89.0 bits (219), Expect = 1e-17
Identities = 77/302 (25%), Positives = 131/302 (42%), Gaps = 41/302 (13%)
Query: 40 KNPVAIKFEP--RRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSL 97
K A+K EP + + L+ E + L + R + + + +++ +LG +
Sbjct: 43 KGSAAMKVEPLMKNKEDEILKMEVYVLKKLQNSRHVCRLLGSGKTETYTYMVMSVLGKEI 102
Query: 98 EDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSV 156
D+ RK S +T + Q++ ++ +HE ++RD+KP N +
Sbjct: 103 GDVRRRLPQRKMSAPSTVRVFIQLVKALQDMHEAGFVHRDVKPSNMALG----------- 151
Query: 157 VKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLS---GTARYMSINTHFG 213
VK+ ++Y+ DFG+++Q P+ + RE ++ S GT RY S+N H
Sbjct: 152 VKN--------EQVVYIFDFGLSRQIMLPDASGKLKLREPRNKSMFRGTVRYCSLNVHLH 203
Query: 214 REQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL-LTPEIP 272
+EQ R DDL + +LPW+G K K E L + K TD+ L P
Sbjct: 204 KEQGRHDDLYGALYAMIETATSTLPWKG------KPKKETSALKE---KTTDVQLCKGCP 254
Query: 273 KQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQE--NGYEEDGHYDWMDLNGGQGWNIKV 330
K F E + R L + + P Y S M ++ + G + ++W +L G N
Sbjct: 255 KSFLEIATTLRKLTYKETPPYG---SFMEKLKADLPKGVKMTDPFEW-NLKGALDENNNG 310
Query: 331 NK 332
NK
Sbjct: 311 NK 312
>CE06796 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 359
Score = 88.2 bits (217), Expect = 2e-17
Identities = 66/278 (23%), Positives = 123/278 (43%), Gaps = 21/278 (7%)
Query: 42 PVAIKFEPR-RSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDL 100
P A+K E + + P L+ + R L G P + +++ L+GP L L
Sbjct: 52 PYAMKVESQSKCLRPVLKLDHAVLRALGHQSGFPSLTSAGRTENFKYVVMQLVGPDLSML 111
Query: 101 FEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKS 159
E+ ++F+ T +A Q +DR+R +HE + RD+K NF
Sbjct: 112 LEFAPQQRFTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNF----------------- 154
Query: 160 CATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRR 219
A G +++++Y++DFG+ +++ + N + + R GT Y + + +QS
Sbjct: 155 -AVGLGEESSIVYMLDFGLTRKYLEHNGSRSL-LRPHGPSVGTFPYAPLASLGFCDQSPI 212
Query: 220 DDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYL 279
DD+E ++ + L+G LPW K N K + + +R L IPK +A+
Sbjct: 213 DDIEGWLYMIVHLLKGGLPWHNSKRALNLPKVREWKMYCRRPGGKHYLFAGIPKGWADIF 272
Query: 280 SYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ + PDY+ + +++ I + + +DW
Sbjct: 273 DVIVNTAPHETPDYNKIANMVLSIARNELIDLTAPFDW 310
>CE06688 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 367
Score = 87.0 bits (214), Expect = 5e-17
Identities = 58/235 (24%), Positives = 103/235 (43%), Gaps = 20/235 (8%)
Query: 86 NILIIDLLGPSLEDL-FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N +++ L+G +L DL + +F+ T+ A Q + + +H ++RDIKP NF +
Sbjct: 96 NFIVMKLIGKNLWDLRMDTAECRFTKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAV 155
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTAR 204
+ + I+++DFG+ ++F + R + GT R
Sbjct: 156 GR----------------KESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTR 199
Query: 205 YMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNK--AKYEKIGLTKQRLK 262
Y IN+ + R+DD+ES ++ + G LPW+ KA + KY+K T + +
Sbjct: 200 YAPINSMLEIDTGRKDDIESWLYMVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIM 259
Query: 263 PTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
DL K+F L Y L F +PDY ++ + + ++ DW
Sbjct: 260 -ADLFYNCPLKEFERILKYVDELDFYSEPDYKFVYCCLQHAAAASKIKDTDPLDW 313
>CE03754 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 366
Score = 86.7 bits (213), Expect = 7e-17
Identities = 65/253 (25%), Positives = 116/253 (45%), Gaps = 30/253 (11%)
Query: 73 IPHAYYFSQEGIHNILIIDLLGPSLEDLFEW---CSRKFSVKTTAMLAKQMIDRVRSIHE 129
IP + ++ ++ +++ LLG +L L + FS T + + Q + ++ +H+
Sbjct: 85 IPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGFSRGTWSRIGIQCLYALKYVHD 144
Query: 130 HDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQ 189
+ I+RD+KP NFL+ + A +++++DFG+A+ F + ++
Sbjct: 145 NGFIHRDVKPQNFLLGN---------------ETDSERARIVHILDFGLARPFAVFHARE 189
Query: 190 H--IPYRER--KSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRG-SLPWQGLKA 244
+ I R R GT RY S N H +EQ R DD+ SL +V G +LPWQ
Sbjct: 190 NKWIARRARGTAEFRGTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKALPWQ---- 245
Query: 245 LNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIM 304
++ E++ K L P ++ +P + + + SL + Q PDY + Q+M
Sbjct: 246 --TDSQRERVEQMKLNL-PAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMIFKCFWQVM 302
Query: 305 QENGYEEDGHYDW 317
+ YDW
Sbjct: 303 ENEKITPSSKYDW 315
>CE01982 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 752
Score = 86.7 bits (213), Expect = 7e-17
Identities = 65/244 (26%), Positives = 117/244 (47%), Gaps = 46/244 (18%)
Query: 88 LIIDLLGPSLEDLF-EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
+++ L+GPSLED+ ++ FS T+ +A Q + ++ +H ++RDIKP N+ +
Sbjct: 517 VVMGLVGPSLEDIRRKYLLGSFSKHTSFNVAIQTVTALQDLHSIGYLHRDIKPANYAVGL 576
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
RE + +Y++DFG+AK + D N + + ++ K L GT RY
Sbjct: 577 EDRE------------------DTVYMLDFGIAKLYVDENGEHKVKRKKVKFL-GTLRYA 617
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFLRGS--LPWQGL----KALNNKAKY------EKI 254
+EQ R+DDLE+ ++ F + S +PW+ L + L +K ++ +
Sbjct: 618 CRACMMQQEQGRKDDLETWIYLVFDLMDESHGMPWRSLCSPKEILKSKNEFFTNFDSSSV 677
Query: 255 GLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGH 314
T +RLK +SY +++++ PDYDY+I+ + E G +
Sbjct: 678 SATLKRLKGL--------------VSYVDNMQYETTPDYDYIINFLKTTATEAGAKISKK 723
Query: 315 YDWM 318
DW+
Sbjct: 724 LDWI 727
Score = 59.3 bits (142), Expect = 1e-08
Identities = 52/235 (22%), Positives = 98/235 (41%), Gaps = 31/235 (13%)
Query: 88 LIIDLLGPSLEDLFE-WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
L++ G +L+++ + + S+ + ++ QM+ ++++H ++R+I P F
Sbjct: 181 LVVSSYGSTLQEILKKTINGPLSMDCSFVVGLQMLRAIQNLHSLGYVHRNINPSAF---- 236
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
+C G D +Y+ DF ++F + K+H+ R + G R+
Sbjct: 237 ------------NCGL--GMDETSLYLQDFRQVRKFEE--NKKHVTARSTVKMFGCGRFA 280
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFL-RGSLPWQGLKALNNKAKYEKIGLTKQRLKPTD 265
+ ++Q R+DDLES + FY + GSL W+ N+A + + K D
Sbjct: 281 NRACQNSKDQGRKDDLESWIYTLFYLIDHGSLSWK------NEADSQIVVQQKDLFMTGD 334
Query: 266 --LLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWM 318
P+ A LS F P+YD +L+ I + DW+
Sbjct: 335 GKEQFSRAPRGLAPLLSKVNGYEFTSAPEYDSFKNLINGIQTSQKLNKKS-CDWL 388
>CE20743 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 540
Score = 85.9 bits (211), Expect = 1e-16
Identities = 66/242 (27%), Positives = 109/242 (44%), Gaps = 26/242 (10%)
Query: 44 AIKFEPRRSDSPQLRDEFRAYRIL---NDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDL 100
A+K E R + + E R+L N++ IP +FS++ N ++ LLG +L DL
Sbjct: 134 AVKIEVRLTSMDFIDHEVTVMRLLSYPNELPHIPKCVFFSKQKDLNFFVMTLLGENLRDL 193
Query: 101 FEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKS 159
C R+F T + L Q++ ++ +HE I+RDIKP+N L+
Sbjct: 194 KLKCPDRRFLRGTWSRLGIQILYALKLMHEKGFIHRDIKPENLLMG-------------- 239
Query: 160 CATSSGGDANLIYVVDFGMAKQFRDPNTKQHI--PYRERKSLSGTARYMSINTHFGREQS 217
A + +++V+DFG+ +Q+ K P R + G+ + S N H G +
Sbjct: 240 -AADDRKRSRIVHVIDFGLTRQWAWSKEKAFYARPLRTKVQFRGSLNFTSSNAHLGYKLG 298
Query: 218 RRDDLESLGHVFFYFLRGSLPWQGLK----ALNNKAKYEKIGLTKQRLKPTDLLTPEIPK 273
R+DDL SL L LPW G+K K E +K + +L ++ +
Sbjct: 299 RKDDLWSLLFT-LVDLNDRLPWHGVKDHMILARQKMNMEDTPTSKYTFEEVELSEDDLEE 357
Query: 274 QF 275
+F
Sbjct: 358 RF 359
>CE16168 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 794
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 35/229 (15%)
Query: 88 LIIDLLGPSLEDLFEWCSRKFSVK-----TTAMLAKQMIDRVRSIHEHDLIYRDIKPDNF 142
+++ L+GPSL+D C RKF V T ++A Q ++ +R +H ++RDIKP NF
Sbjct: 549 IVMSLVGPSLDD----CRRKFGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANF 604
Query: 143 LISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGT 202
A G + ++++DFG+ + + DP TKQH R++ GT
Sbjct: 605 ------------------AVGVGAKESTVFMLDFGIGRSYLDPKTKQHRAPRKKVKFLGT 646
Query: 203 ARYMSINTHFGREQSRRDDLESLGHVFF--YFLRGSLPWQGLKALNNKAKYEKIGLTKQR 260
RY S +Q R+DDLE ++ F + + + W+ + KI KQ
Sbjct: 647 LRYASRACMLEVDQGRKDDLECWIYMVFDIFDPKNGVSWK------KQRDRVKIREAKQL 700
Query: 261 LKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGY 309
P + Y SL+F P+Y L+ + +GY
Sbjct: 701 FFDGKAQYDYAPISLRPIIIYINSLQFQTTPEYANLVKTLYTSSSASGY 749
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/197 (23%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 116 LAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVD 175
+A Q +D ++ +H+ + R+IKP +F + + E IY+ D
Sbjct: 225 VALQTLDAIQYLHQAGFLNRNIKPASFSVGLNEEETK------------------IYMTD 266
Query: 176 FGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFL-- 233
+ + + DP+TK+ P R GTARY SI ++Q R+DD+E+ ++ + +
Sbjct: 267 YRLVRTHIDPSTKKVRPARTGLKYGGTARYASIAGLKKKDQGRKDDVEAWIYMIYDLIDP 326
Query: 234 RGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDY 293
L W+ N K EK L T ++P++F + + +D PDY
Sbjct: 327 ENGLSWRKSPRCNMMIK-EKENFKYHVLPHT---YDKVPEEFKKLVDLVHGYSYDSLPDY 382
Query: 294 DYLISLMTQIMQENGYE 310
++ + + G++
Sbjct: 383 AAFKEIVQNVGKSKGHD 399
>CE13469 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 342
Score = 85.5 bits (210), Expect = 2e-16
Identities = 54/193 (27%), Positives = 88/193 (44%), Gaps = 21/193 (10%)
Query: 127 IHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPN 186
+H + RD+KP NF + S + I++ DFG+A+++ D N
Sbjct: 126 LHRIGFVSRDVKPGNF----------------APGVKSNRQSRTIFMYDFGLARKYIDKN 169
Query: 187 TKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALN 246
Q IP R+ GT RY S+N H + RRDDLES + RG+LPW+ +
Sbjct: 170 N-QVIPTRKEVGWRGTTRYGSLNAHKRLDLGRRDDLESWFYGLVEMTRGTLPWRNVV--- 225
Query: 247 NKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQE 306
+++ ++ + T L E P Q+ + + S F+ PDY + L+ + +E
Sbjct: 226 DRSSVQRAKEASRNTGRTQFLF-ETPSQYDKIFTIVDSYAFESAPDYKQINKLLVEAREE 284
Query: 307 NGYEEDGHYDWMD 319
+ H+DW D
Sbjct: 285 RQLRDREHWDWED 297
>CE08953 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 346
Score = 84.7 bits (208), Expect = 3e-16
Identities = 66/236 (27%), Positives = 110/236 (45%), Gaps = 28/236 (11%)
Query: 85 HNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
++ +++ LLG SLE L + F+V T + ++ ++ IH+ I+RD+KP N +
Sbjct: 91 YSYVVMTLLGESLESLMKKHGPFFNVSTQMRIGICLLFGIKQIHDIGFIHRDLKPANVAL 150
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF---RDPNTKQHIPYRERKSLSG 201
D V+DFG+A+Q+ ++ K P RE+ G
Sbjct: 151 ----------------GNKGSPDERYFIVLDFGLARQYITDKEDGKKMRRP-REKALFRG 193
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
T+RY S+ H EQ R DDL +L ++ LR L W L++K +IG K+ +
Sbjct: 194 TSRYCSVAMHDRFEQGRVDDLWALIYMLAE-LRCQLAWSD---LDDKV---EIGEMKRHV 246
Query: 262 KPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+L + P Q E++ R+ +F PDY+ L +L+ M+ Y+ Y W
Sbjct: 247 ADQNLFA-KSPIQMLEFVKIVRATQFYHRPDYEKLFNLLNDAMKSAKYKWSDPYHW 301
>CE04892 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 758
Score = 84.0 bits (206), Expect = 5e-16
Identities = 63/236 (26%), Positives = 111/236 (46%), Gaps = 30/236 (12%)
Query: 88 LIIDLLGPSLEDLF-EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
+++ L+GPSLED+ ++ FS T+ +A Q + +R +H ++RDIKP N+ +
Sbjct: 523 VVMGLVGPSLEDIRRKYLLASFSKHTSFNVAIQTVTALRDLHSLGYLHRDIKPANYAVGL 582
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
+RE + +Y++DFG+AK + D N I ++ K L GT RY
Sbjct: 583 DERE------------------DTVYMLDFGIAKLYVDENGVHKIKRKKVKFL-GTLRYA 623
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFL--RGSLPWQGLKALNNKAKYEKIGLTKQRLKPT 264
+EQ R+DDLE+ ++ F + +PW+ L +I +K T
Sbjct: 624 CRACMMQQEQGRKDDLETWIYLVFDLMDEAHGMPWRAL------CDPREILKSKNTFFAT 677
Query: 265 --DLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWM 318
+ I K+ + + Y +++D PDY Y+++ + + G + DWM
Sbjct: 678 FDNFQFSNILKRLKDLVVYVDDMQYDTTPDYSYILNFLKTTANDVGAKITKKLDWM 733
Score = 57.8 bits (138), Expect = 4e-08
Identities = 54/237 (22%), Positives = 96/237 (39%), Gaps = 27/237 (11%)
Query: 88 LIIDLLGPSLEDLFEWCSR-KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
LI+ G +L ++ + + + S+ + ++ QM+ ++++H I+R+I P +F
Sbjct: 177 LIVSPYGATLNEIMKKATMGQLSMDCSFVVGLQMLRAIQNLHSIGYIHRNISPASF---- 232
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
C G D +++ DF A++F + K+H+ R + G R+
Sbjct: 233 ------------HCGL--GMDEPTLFLQDFRQARKFEE--NKKHVTARTNVKMYGCGRFA 276
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFL-RGSLPWQGLKALNNKAKYEKIGLTKQRLKPTD 265
+ ++Q R+DDLES + FY + GSL W K NN + D
Sbjct: 277 NRACQGSKDQGRKDDLESWVYTLFYLMDNGSLSW---KRENNSLVVIQQKDAFMAGNGKD 333
Query: 266 LLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNG 322
T P+ LS F PDY+ + + I + DW+ G
Sbjct: 334 QFT-HAPRDLVPLLSVINGYEFSSAPDYEVFRNCLEGIQTVQNLNKKS-CDWLGKAG 388
>CE05212 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 373
Score = 83.6 bits (205), Expect = 6e-16
Identities = 71/262 (27%), Positives = 119/262 (45%), Gaps = 33/262 (12%)
Query: 65 RILNDVRGIPHAYYFSQEGIHN---ILIIDLLGPSLEDLFEWCSR-KFSVKTTAMLAKQM 120
R LND + H G +++ LLG +L+ L + +F+ T + + Q
Sbjct: 75 RKLNDGESVIHVPKLLLSGKRKKYCYMVMTLLGKNLKCLKNKRPKERFTRGTWSRIGIQC 134
Query: 121 IDRVRSIHEHDLIYRDIKPDNFLI-SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMA 179
+ ++ +H+ ++RDIKP NF++ +E +E A +++++DFG+A
Sbjct: 135 LYGLKYMHDCGFVHRDIKPQNFMMGNEDDKER----------------ARIVHILDFGLA 178
Query: 180 KQFR--DPNTKQHIPYRERKSLS--GTARYMSINTHFGREQSRRDDLESLGHVFFYFLRG 235
+ F ++K R R + GT RY S N HF +EQ R DD+ SL V L G
Sbjct: 179 RSFAKFSESSKTWSARRARGTAEFRGTLRYTSPNVHFRKEQGRVDDIWSLLFVLIE-LNG 237
Query: 236 SLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDY 295
LPWQ N K E++ K + D++ +P + + + R+L PDY
Sbjct: 238 GLPWQ------NVQKREEVEAMKMIMTDQDVML-NMPPCMCDIIPHFRTLDCYMRPDYLL 290
Query: 296 LISLMTQIMQENGYEEDGHYDW 317
+ + Q+M G +DW
Sbjct: 291 VFKALWQVMLNEGQTTSSRFDW 312
>CE09980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 380
Score = 83.2 bits (204), Expect = 8e-16
Identities = 63/239 (26%), Positives = 109/239 (45%), Gaps = 27/239 (11%)
Query: 86 NILIIDLLGPSLEDLFE-WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N +++ L+G +L DL + KF++ T+ A Q + + +H ++RDIKP NF
Sbjct: 96 NFIVMKLIGKNLWDLRQDRGDGKFTMGTSLKAASQCLVSIEHLHSFGYLHRDIKPGNF-- 153
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF-RDPNTKQHIPYRERKSLSGTA 203
+ + ++I+++DFG+ +++ + K R GT
Sbjct: 154 --------------AAGRKESNEHHVIFMLDFGLCREYVKRAEGKDLRAARTTAPFRGTT 199
Query: 204 RYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQ--RL 261
RY + + ++QSR+DD+ES ++ + G LPW+ LKA + EK+ KQ R
Sbjct: 200 RYAPLASMLQQDQSRKDDIESWLYMVVEWTSGGLPWRKLKAHDR----EKVLQYKQDLRT 255
Query: 262 KP---TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
KP D L K+F L Y +L + PDY ++ + N ++ DW
Sbjct: 256 KPDILDDFLFLCPKKEFTRILKYLDTLGYYAVPDYKFIYFCVQHAANANKIKDADPLDW 314
>CE07450 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 380
Score = 83.2 bits (204), Expect = 8e-16
Identities = 63/239 (26%), Positives = 109/239 (45%), Gaps = 27/239 (11%)
Query: 86 NILIIDLLGPSLEDLFE-WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
N +++ L+G +L DL + KF++ T+ A Q + + +H ++RDIKP NF
Sbjct: 96 NFIVMKLIGKNLWDLRQDRGDGKFTMGTSLKAASQCLVSIEHLHSFGYLHRDIKPGNF-- 153
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF-RDPNTKQHIPYRERKSLSGTA 203
+ + ++I+++DFG+ +++ + K R GT
Sbjct: 154 --------------AAGRKESNEHHVIFMLDFGLCREYVKRAEGKDLRAARTTAPFRGTT 199
Query: 204 RYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQ--RL 261
RY + + ++QSR+DD+ES ++ + G LPW+ LKA + EK+ KQ R
Sbjct: 200 RYAPLASMLQQDQSRKDDIESWLYMVVEWTSGGLPWRKLKAHDR----EKVLQYKQDLRT 255
Query: 262 KP---TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
KP D L K+F L Y +L + PDY ++ + N ++ DW
Sbjct: 256 KPDILDDFLFLCPKKEFTRILKYLDTLGYYAVPDYKFIYFCVQHAANANKIKDADPLDW 314
>CE25045 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 346
Score = 82.4 bits (202), Expect = 1e-15
Identities = 65/236 (27%), Positives = 111/236 (46%), Gaps = 28/236 (11%)
Query: 85 HNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
++ +++ LLG SL+ L + +V T + ++ ++ +H+ ++RD+KP N
Sbjct: 90 YSYMVMTLLGESLDSLLKKHGPFLNVSTQVRIGICILFGIKQVHDIGYLHRDLKPAN--- 146
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF---RDPNTKQHIPYRERKSLSG 201
V C S+ D V+DFG+A+Q+ D K P RE+ G
Sbjct: 147 -----------VAMGCKGSA--DERYFLVLDFGLARQYIADEDDGLKMRRP-REKTYFRG 192
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
TARY S+ H EQ R DDL +L ++ +R L W +++K +IG K+++
Sbjct: 193 TARYCSVAMHDRYEQGRVDDLWALVYILAE-MRCRLAWHD---VDDKV---EIGEMKRKI 245
Query: 262 KPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
++L + P Q ++ RS F PDY+ L L+ +M+ Y+ Y W
Sbjct: 246 H-DEVLFAKSPVQMLSFVKTVRSTLFYHRPDYEKLFKLLEDVMKCANYKWSDPYHW 300
>CE19741 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 330
Score = 82.0 bits (201), Expect = 2e-15
Identities = 62/265 (23%), Positives = 119/265 (44%), Gaps = 22/265 (8%)
Query: 42 PVAIKFEPRRSD-SPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDL 100
P A+K E +S P L+ + L + G P + +++ L+GP L L
Sbjct: 49 PYAMKVEAEKSCVRPVLKLDHAVLTALGNQTGFPSLMDSGRTDSFKYIVMQLVGPDLSTL 108
Query: 101 FEWCSR-KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKS 159
E+ + +FS T +A Q +DR+R +H + RD+K NF
Sbjct: 109 LEFAPQNRFSQSTIYKIALQTLDRLRVLHHAGWLNRDVKAQNF----------------- 151
Query: 160 CATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRR 219
A G ++N++Y++DFG+ ++F + + +H+ R GT Y +++ +Q+
Sbjct: 152 -AVGFGEESNIVYMLDFGLTRRFLELDGSRHL-LRPWGPSVGTFPYAPLSSLGFLDQTPA 209
Query: 220 DDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYL 279
DD+E ++ + L G LPW K + AK + + +R L +IP +++
Sbjct: 210 DDVEGWLYMIIHLLNG-LPWHNSKRSLSLAKVREWKMYCRRAGGRTQLFRDIPDGWSDVF 268
Query: 280 SYCRSLRFDQDPDYDYLISLMTQIM 304
+ + PDY +++ + ++
Sbjct: 269 DIILKTSYQEYPDYTKILNKVMSML 293
>CE12108 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 308
Score = 82.0 bits (201), Expect = 2e-15
Identities = 70/280 (25%), Positives = 123/280 (43%), Gaps = 29/280 (10%)
Query: 44 AIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIH---NILIIDLLGPSLEDL 100
A+K E P L+ E + L+ ++G H +G H N +++ LG SL+D
Sbjct: 45 ALKAELATEKIPLLKLELYVMQKLS-MKGPKHMATLIDKGRHENFNYIVMKFLGKSLQDA 103
Query: 101 FEWCSRKFSVKTTAMLAK-QMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKS 159
+ +A+ A Q ++ + +H ++RD+KP NF + +
Sbjct: 104 KKTGPDGHLTLGSAIGASIQCLEALEELHWCGFLHRDVKPGNFCLGRAEL---------- 153
Query: 160 CATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRR 219
G+ I+V+DFG+ ++F D P R + GT RY I +H E R+
Sbjct: 154 ------GELRKIFVLDFGLCRKFVDDRNVMLQP-RRKAPYRGTPRYAPIASHNRAEHGRK 206
Query: 220 DDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP--TDLLTPEIPKQFAE 277
DD+ES ++ F +LPW+ + + + +K R P T LL ++
Sbjct: 207 DDVESWFYMLVDFTNAALPWKVVNEIPQVGEMKK----NSRFDPLVTQLLAGCPVDEYRL 262
Query: 278 YLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+++ L F +P+Y + S + ++MQ +E YDW
Sbjct: 263 IMNHIDGLSFFMEPNYGLIYSTLKRLMQTRNIQE-FPYDW 301
>CE15314 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 390
Score = 80.9 bits (198), Expect = 4e-15
Identities = 64/241 (26%), Positives = 112/241 (45%), Gaps = 31/241 (12%)
Query: 88 LIIDLLGPSLEDLFEWCS--RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLIS 145
+++ L G +L DL + RKFS+ T LA+Q + +R +H + I+RDIKP +F I
Sbjct: 94 IVMPLYGENLFDLMMNTNKDRKFSMATGLHLAEQTLTAIRDLHRNGFIHRDIKPSHFCIG 153
Query: 146 EFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKS---LSGT 202
RE+ G + +Y++DFG+ K+ R + RK+ G
Sbjct: 154 ---REVD-------------GQHHQVYLLDFGLCKRPRFAKKNDEAEEQMRKNAIHYRGV 197
Query: 203 ARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLK 262
+Y S++ H G+ +DD+ES ++ F G+LPW AL NK + + K+R+
Sbjct: 198 VKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPW----ALLNKESEQDVLHLKRRIT 253
Query: 263 PTDL-----LTPEIPKQFAEYLSYCRSLR-FDQDPDYDYLISLMTQIMQENGYEEDGHYD 316
+ TPE F + L+ R + + +YD + + ++ +++ D
Sbjct: 254 APMVAAVWRTTPETTAGFFDLLTVIREPKDVAEFVEYDRIADGIQKLFEKSKSNTQEPPD 313
Query: 317 W 317
W
Sbjct: 314 W 314
>CE05474 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 332
Score = 80.9 bits (198), Expect = 4e-15
Identities = 60/237 (25%), Positives = 107/237 (44%), Gaps = 21/237 (8%)
Query: 82 EGIHNILIIDLLGPSLEDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPD 140
+GIH I ++ ++G +L D + S SV + Q+I+ + +H I+RD+KP
Sbjct: 105 QGIHYI-VMHMIGRALVDYMKTSMSGAISVNCALSVGIQLIEALEDLHNCGFIHRDLKPS 163
Query: 141 NFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLS 200
N R + +Y++ FG+++++ D + P R+
Sbjct: 164 NICFGRKDRN----------------ELGKLYLLSFGISRRYLDSKNQMRKP-RDNVEFR 206
Query: 201 GTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQR 260
GT RY S+N H +E +R+DDLES +V + G LPW+GL A+ ++
Sbjct: 207 GTVRYASLNCHQLQELNRKDDLESAFYVIVEMITGQLPWKGLPDGAAVARVKQQSRHPSA 266
Query: 261 LKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ L P ++ E + S + PDY + +++ + M+ + E YDW
Sbjct: 267 I-ALFLRAPCPMEELREVMILIDSYNYFTAPDYVNICNILRRAMRRSPQPEH-PYDW 321
>CE15237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 350
Score = 80.5 bits (197), Expect = 5e-15
Identities = 72/285 (25%), Positives = 121/285 (42%), Gaps = 42/285 (14%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIH---NILIIDLLGPSLED 99
V IK EP R ++L ++G PH G N +++ LLGP++ D
Sbjct: 74 VVIKIEPVVLKGRPRRRMILEQKVLYRLQGRPHVPIMCASGHTEQLNFIVMQLLGPNIGD 133
Query: 100 LFEWCS-RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
L + ++ S T A + Q I +R +H I+RD+KP N
Sbjct: 134 LKKRSPVKRLSQTTVARIMIQGIAALRDVHSLGYIHRDVKPANM---------------- 177
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
C + +++ +VD+GM ++F++ + + R + GT RY S+ H G+EQ+
Sbjct: 178 -CFGVTQSTRHVLKLVDYGMVRRFKNVDGTRR-KQRYKPGFRGTLRYSSVRVHDGKEQTP 235
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIP------ 272
DD S+ + L +LPW+ + + I TK D TP P
Sbjct: 236 VDDFVSMAYSGAELLLVNLPWKLVST-------DDIRQTK-----VDFNTPNSPYLLLTG 283
Query: 273 KQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
F+ + +LR + +PD+ L +L+ + + E YDW
Sbjct: 284 PYFSVFCGAIFNLRSEDEPDHSSLQNLLCDMTRGKSLRE--AYDW 326
>CE09979 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 311
Score = 80.5 bits (197), Expect = 5e-15
Identities = 62/239 (25%), Positives = 110/239 (45%), Gaps = 28/239 (11%)
Query: 83 GIHNILIIDLLGPSLEDLFEWCSRK-FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDN 141
G N +++ L+G SL+DL + +++ S+ + + Q ++ + +H ++RD+KP N
Sbjct: 86 GSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGN 145
Query: 142 FLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSG 201
+ I + EL++ +Y++DFGMA++F D N P R G
Sbjct: 146 YTIG--RAELNE--------------LRKVYILDFGMARKFTDNNGVIRKP-RAAAGFRG 188
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
T RY I H +E R+DD+E ++ G +PW+ + +N +G KQ +
Sbjct: 189 TVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMN------AVGQAKQAI 242
Query: 262 KPTD---LLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ T + P + E + S + DP+Y LM Q + G + + YDW
Sbjct: 243 RNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQTLANCG-KPEYPYDW 300
>CE07449 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 311
Score = 80.5 bits (197), Expect = 5e-15
Identities = 62/239 (25%), Positives = 110/239 (45%), Gaps = 28/239 (11%)
Query: 83 GIHNILIIDLLGPSLEDLFEWCSRK-FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDN 141
G N +++ L+G SL+DL + +++ S+ + + Q ++ + +H ++RD+KP N
Sbjct: 86 GSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGN 145
Query: 142 FLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSG 201
+ I + EL++ +Y++DFGMA++F D N P R G
Sbjct: 146 YTIG--RAELNE--------------LRKVYILDFGMARKFTDNNGVIRKP-RAAAGFRG 188
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
T RY I H +E R+DD+E ++ G +PW+ + +N +G KQ +
Sbjct: 189 TVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMN------AVGQAKQTI 242
Query: 262 KPTD---LLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ T + P + E + S + DP+Y LM Q + G + + YDW
Sbjct: 243 RNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQALANCG-KPEYPYDW 300
>CE24572 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 382
Score = 80.1 bits (196), Expect = 7e-15
Identities = 70/288 (24%), Positives = 122/288 (42%), Gaps = 32/288 (11%)
Query: 40 KNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHN----ILIIDLLGP 95
K A+K E L E LN ++ PH GI N +++ L+G
Sbjct: 93 KRHFAMKCESVNMKRAILPHEAGVLLALNHLKS-PHFLEMVDHGIVNNRFLFVVLKLVGM 151
Query: 96 SLEDLFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
+L D+ +K+++ TT +A+Q + +R +H ++RDIKP NF I RE D
Sbjct: 152 NLWDMRAHLPDKKYTLTTTLRIAEQTLAGLRDLHRVGFLHRDIKPPNFAIG---REEDD- 207
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
+ ++++DFG+ ++ P R+ + GT RY ++ H +
Sbjct: 208 ------------TYHTVFLLDFGLCRKIAMKGKDLRTP-RKECAFRGTTRYAALAAHDNK 254
Query: 215 EQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTD-----LLTP 269
EQSR+DD+ES ++ + +PW+ + + + + K RL+ + L
Sbjct: 255 EQSRKDDIESWWYMIAEMIVFDIPWKQFRGTDR----DNVRGMKWRLRADETYFKFLFRK 310
Query: 270 EIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+Q + L Y L + PDYD++ + N DW
Sbjct: 311 CCYEQMSAILLYLDQLSYSSIPDYDFVYHHLQAAAIVNNCSAKSPPDW 358
>CE02393 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 366
Score = 80.1 bits (196), Expect = 7e-15
Identities = 55/205 (26%), Positives = 94/205 (45%), Gaps = 22/205 (10%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGI---HNILIIDLLGPSLED 99
VAIK EP R +L ++G PH + G N +++ LL +L D
Sbjct: 94 VAIKAEPLVRKGKIARRMILEQAVLVKLQGKPHVPWIFGSGHTENFNFIVLQLLSANLGD 153
Query: 100 LFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
+ +RK S + +A Q I +R +H+ ++RDIKP N
Sbjct: 154 IRRMSPTRKLSKSSVGRIAVQAIAALRDLHDVGYLHRDIKPGNM---------------- 197
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
C + +++ ++DFG+ ++++DP+ + +R + GT RY+S H EQ+
Sbjct: 198 -CFGITSKTRHVLMLLDFGLVRRYKDPDGEWRT-HRVKAGFRGTQRYVSTRVHRRLEQTP 255
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLK 243
DD+ SL + L G LPW+ ++
Sbjct: 256 TDDMVSLLYTLIELLAGELPWRNIE 280
>CE22732 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 421
Score = 79.3 bits (194), Expect = 1e-14
Identities = 63/241 (26%), Positives = 112/241 (46%), Gaps = 31/241 (12%)
Query: 88 LIIDLLGPSLEDLFEWCS--RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLIS 145
+++ L G +L +L + RKFS+ T LA+Q + +R +H + I+RDIKP +F I
Sbjct: 94 IVMPLYGENLYELMMNTNKDRKFSMATGLHLAEQTLAAIRDLHRNGFIHRDIKPSHFCIG 153
Query: 146 EFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKS---LSGT 202
RE+ G + +Y++DFG+ K+ R + RK+ G
Sbjct: 154 ---REID-------------GQHHQVYLLDFGLCKRPRFVKKNDEAEEQMRKNAIHYRGV 197
Query: 203 ARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLK 262
+Y S++ H G+ +DD+ES ++ F G+LPW AL NK + + K+R+
Sbjct: 198 VKYASVHAHQGKNLGYKDDMESWWYMVLEFFLGALPW----ALLNKESEQDVLHLKRRIT 253
Query: 263 PTDL-----LTPEIPKQFAEYLSYCRSLR-FDQDPDYDYLISLMTQIMQENGYEEDGHYD 316
+ TPE F + L+ R + + +YD + + ++ +++ D
Sbjct: 254 APMVASVWRTTPETTAGFFDLLTIIREPKDVAEFVEYDRIADGIQKLFEKSKSNTQEPPD 313
Query: 317 W 317
W
Sbjct: 314 W 314
>CE04522 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 310
Score = 79.3 bits (194), Expect = 1e-14
Identities = 68/288 (23%), Positives = 119/288 (40%), Gaps = 38/288 (13%)
Query: 41 NPVAIKFEPRRSDSP-QLRDEFRAYRILNDVRGIPHAYYFSQEGIHN-----ILIIDLLG 94
N A+K E ++ P +L+ E +++ + R H G + L+++L G
Sbjct: 49 NFYAMKVEKKQEKKPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAG 108
Query: 95 PSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
SL DL + F+ T +++Q ++ +H+H I+RD+KP NF
Sbjct: 109 SSLADLKRNRGKAFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANF------------ 156
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
A + + IY++DFG++++ + K P R GT ++ S++ H G
Sbjct: 157 ------ACGADDKQHTIYILDFGISRRIINNQNKLKTP-RVTIRFKGTLKFASLSCHKGI 209
Query: 215 EQSRRDDLESLGHVFFYFLRG-----SLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTP 269
E +DD ES +FY L L W+G + K ++ K+ +
Sbjct: 210 EMGWKDDCES----WFYMLLDLIVPFGLVWRGANDKDTVCKLKEEARGKKEMFQGIKCGV 265
Query: 270 EIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
E+ K + Y L++ DY Y+ + G D YDW
Sbjct: 266 ELNK----IIVYIDKLQYQDHVDYQYIYKTLVDACDTCGGNMDAPYDW 309
>CE12690 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 425
Score = 77.8 bits (190), Expect = 3e-14
Identities = 71/279 (25%), Positives = 119/279 (42%), Gaps = 33/279 (11%)
Query: 35 LNGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQE---GIHNILIID 91
++ K A+K E DS + E +L +R PH+ + ++ G + ++
Sbjct: 45 IDSEGKIEAAMKVEKLSKDSKKRSIE---KDVLEALRDSPHSAHIIEQLLIGDYRFTVMT 101
Query: 92 LLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQREL 151
L GP+L + KFS T L+ + + ++ +HEH I+RD++P N +S ++
Sbjct: 102 LSGPTLGIIKHIMDNKFSDSTILRLSMRTLMAIKDLHEHGFIHRDLEPFNIALSPYK--- 158
Query: 152 SDGSVVKSCATSSGGDANLIYVVDFGMAKQF-RDPNTKQHI-PYRERKSLSGTARYMSIN 209
+ I ++DFG A+QF R+ N K + R++ G+ +Y S
Sbjct: 159 ---------------SSRNILLLDFGEARQFARNDNGKWMLRKPRDKAPFRGSDQYCSPR 203
Query: 210 THFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTP 269
H EQ R DDL S +VF LR LPW + K G K+ L L +
Sbjct: 204 MHNHEEQGRVDDLWSWLYVFVE-LRAFLPW------TDSTSRFKYGPLKRELLDDLLASD 256
Query: 270 EIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENG 308
F ++ R ++ PDY + ++ M G
Sbjct: 257 PFITTFCPIVTLLREGKYADRPDYGKIYEILAAKMTSMG 295
>CE04980 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 361
Score = 77.0 bits (188), Expect = 6e-14
Identities = 64/286 (22%), Positives = 125/286 (43%), Gaps = 27/286 (9%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHA---YYFSQEGIHNILIIDLLGPSLED 99
VAIK EP++ + +L ++G PH Y +N +I+ +L ++ D
Sbjct: 88 VAIKVEPKKRRGKLAKRMILEQHVLAKMQGKPHVPMIYGSGHAEKYNFIIMQILSINVGD 147
Query: 100 LFEWC-SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
+ + ++K S + + Q+I ++ +HE ++RD+KP N F
Sbjct: 148 IKKSSPNKKLSQCSVGRIIHQVIAALQDLHETGYVHRDVKPANMCFGIFPHS-------- 199
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
+ + ++DFG+ ++++ + + P R R GT RY+SI H EQS
Sbjct: 200 ---------RHTLILLDFGLVRRYKMESGEWREP-RLRAGFRGTTRYVSIRVHRRCEQSP 249
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEY 278
DDL S+ + + L G LPW+ L+ + +++ +T+ + P L ++
Sbjct: 250 YDDLVSVMYTAYELLAGELPWKHLEKSEEVVQLKEV-MTENGINPE--LFQGDKSVLIDF 306
Query: 279 LSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQ 324
+ ++P Y+ LI + + + Y+W + + GQ
Sbjct: 307 FKQVSEMDPMKEPCYEKLIECIKVLYAPKVLTDP--YEWEESSKGQ 350
>CE15320 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 368
Score = 76.3 bits (186), Expect = 1e-13
Identities = 68/283 (24%), Positives = 118/283 (41%), Gaps = 34/283 (12%)
Query: 40 KNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAY----YFSQEGIHNILIIDLLGP 95
K AIK E D +++ E L GIP + ++ + +++ L+G
Sbjct: 92 KEDCAIKVEHESQDIRRMKLEITVLLALRGSMGIPEILAQGKWQHEDNKSHYIVMQLVGR 151
Query: 96 SLEDLFEWCSRKFSVKTTAMLAK-QMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
+L D+ K + T A Q++ + +H ++RD+KP N I
Sbjct: 152 NLSDVRRALPHKRITERTLYRAMIQVLKALSLVHGAGFLHRDLKPSNCCIGAI------- 204
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
D IY++D+G+ +Q+ D P R L GT RYMS++ H +
Sbjct: 205 ------------DCTRIYLIDYGLTRQYLDKGGIVRKP-RAGVGLRGTVRYMSLDAHARQ 251
Query: 215 EQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQ 274
+ ++DL + + G LPW K N K ++ + + ++T +
Sbjct: 252 DLGPKNDLVAFLYTTIECGDGYLPWSHEKTHENIIKLKQAHIGDKLCTKQPVMT-----K 306
Query: 275 FAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
AEY+ SL + PDY+ L++LM + + +E YDW
Sbjct: 307 AAEYI---ESLNYHSIPDYEKLLALMEECNPPD-LKESEPYDW 345
>CE19439 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 330
Score = 75.5 bits (184), Expect = 2e-13
Identities = 59/236 (25%), Positives = 105/236 (44%), Gaps = 29/236 (12%)
Query: 88 LIIDLLGPSLEDLF-EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
+++ L+G SL L E ++ F+ T + Q ++ V +H+ I+RD+KP N+
Sbjct: 99 IVMQLVGKSLSGLKKERPNQIFTFGTGMGVGSQCLEAVEELHKQGFIHRDLKPQNY---- 154
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSL--SGTAR 204
A+ + +LIY++DFG+A+++ + + P RE + SGT R
Sbjct: 155 --------------ASGQDDERHLIYILDFGIARKYLNDKKEMKTP-RESVAFKASGTIR 199
Query: 205 YMSINTHFGREQSRRDDLESLGHVFF-YFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP 263
+ ++ H E +DD ES ++ L G LPW+ K N K ++ R
Sbjct: 200 FAPLSCHRYTEMGPKDDCESWFYLLIDLILEGGLPWRHCKVKNEVLKIKE----NTRKDN 255
Query: 264 TDLLTPEIPK--QFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
L IP+ + + L Y S + DY ++ + + G + + YDW
Sbjct: 256 RAALYKGIPQTSELNKILDYIDSRAYQDRIDYKFIYKALGEACSNAGCDINAPYDW 311
>CE00935 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 351
Score = 75.5 bits (184), Expect = 2e-13
Identities = 58/192 (30%), Positives = 81/192 (41%), Gaps = 31/192 (16%)
Query: 107 KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATS-SG 165
+F +TT LA + ++ IHE +RDIKP N C T G
Sbjct: 109 RFCEQTTLRLAMATLFAIKQIHEVGFTHRDIKPGN------------------CVTGVHG 150
Query: 166 GDANLIYVVDFGMAKQFRDPNTKQHIPYRERKS----LSGTARYMSINTHFGREQSRRDD 221
DA +Y++D+GM +QF R +S GT RY S+N H +EQ R DD
Sbjct: 151 SDAKNVYLIDYGMVRQFTAKRENGETALRRARSGEQLFRGTPRYCSMNVHNRKEQGRVDD 210
Query: 222 LESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSY 281
L S ++ L LPW+ L EK + + + L PK+FA Y
Sbjct: 211 LWSWLYMLIE-LHCGLPWRRLTD-------EKEIMDAKIACSMETLLKGCPKEFANIHKY 262
Query: 282 CRSLRFDQDPDY 293
+L + PDY
Sbjct: 263 LETLEYKSRPDY 274
>CE24727 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 331
Score = 75.1 bits (183), Expect = 2e-13
Identities = 62/225 (27%), Positives = 99/225 (43%), Gaps = 29/225 (12%)
Query: 79 FSQEGIHNILIIDLLGPSLEDL-FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDI 137
F Q + +++ ++GPSLE+L ++ T Q + + H+ ++RDI
Sbjct: 58 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 117
Query: 138 KPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERK 197
KP N+ I G + IYV+DFG+A+++R PN Q P R +
Sbjct: 118 KPANYCIGY------------------GSKSETIYVLDFGLARKYRLPN-GQVRPPRPKT 158
Query: 198 SLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSL-PWQGLKALNNKAKYEKIGL 256
+ GT RY S +H E RRDD ES +F + +L W+GL + AK +++
Sbjct: 159 KMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTLIDWKGLTRPDAYAKKQELF- 217
Query: 257 TKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMT 301
T L T E F Y +L +D + + L +T
Sbjct: 218 -------TKLKTYEKHPMFKVISIYLDNLVYDSEVKFGVLREAIT 255
>CE14744 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 429
Score = 74.3 bits (181), Expect = 4e-13
Identities = 70/281 (24%), Positives = 120/281 (41%), Gaps = 44/281 (15%)
Query: 36 NGGSKNPVAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHN---ILIIDL 92
N +K A+K E + L+ E I+ ++ P A + +GI+ +++ L
Sbjct: 42 NKSTKQEAALKIEKMTAGDNLLKFE---REIMVAMQHEPTAIHIYDDGIYKDYRYIVMTL 98
Query: 93 LGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELS 152
GP L+ + E + F+ T + + + ++++HE+ I+RD+KP NF + L
Sbjct: 99 CGPDLQKIAELMNNNFNQDTIIRVCIRTLLAIKTMHEYTYIHRDLKPCNFAVDFNPNSLH 158
Query: 153 DGSVVKSCATSSGGDANLIYVVDFGMAKQF--RDPNTKQHIPY-RERKSLSGTARYMSIN 209
+Y+ D+GMA+++ +D K + R GT RY S+N
Sbjct: 159 ------------------VYLFDYGMARKYATKDSGNKWQLRRPRNPAQFRGTVRYCSLN 200
Query: 210 THFGREQSRRDDLESLGHVFFYFLR---GSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL 266
H +E SR DDL S +F+ L LPW + E+I K+ L
Sbjct: 201 MHKRKELSRVDDLWS----WFFMLMEMYAPLPW------TSSNIPERIEALKEDHLNEYL 250
Query: 267 LTPEIPKQFAEYLSYCRSLRFDQDPD----YDYLISLMTQI 303
F + Y S+++ PD YD L + +T+I
Sbjct: 251 SKDSFLSSFLPLVEYLNSVQYADRPDYMKIYDILYAKLTEI 291
>CE07685 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 373
Score = 73.2 bits (178), Expect = 8e-13
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 28/214 (13%)
Query: 106 RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSG 165
+ FS T A L+ Q+++ +R +H +I+RD+K N C +
Sbjct: 114 KHFSKSTAARLSVQLLEALRDMHASGIIHRDVKGSN------------------CGWHAS 155
Query: 166 GDANLIYVVDFGMAKQFRDP--NTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLE 223
L++ + F DP NT +H R+ GT+ Y S H +Q RRDDL
Sbjct: 156 SRRILLFDLGFSRKYLELDPSTNTMRHRAARKTPGFMGTSNYCSTYAHDECDQGRRDDLW 215
Query: 224 SLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCR 283
+ + GSLPW NN+ K I ++K + K L + P++ A + R
Sbjct: 216 AWLYSTVEMFLGSLPW------NNEDK--TILVSKMKKKIGKKLFFKCPREIALMYEHIR 267
Query: 284 SLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
L+FD PDY +++ Q+ +E D+
Sbjct: 268 QLKFDSTPDYQMMLNHFQQMYARLEIDESEPMDF 301
>CE24851 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 290
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/254 (23%), Positives = 114/254 (44%), Gaps = 32/254 (12%)
Query: 73 IPHAYYFSQEGIHNILIIDLLGPSLEDLFEW---CSRKFSVKTTAMLAKQMIDRVRSIHE 129
IP+ + ++ + +++ LLG +L+DL ++ FS T + + Q + ++ +H
Sbjct: 18 IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHY 77
Query: 130 HDLIYRDIKPDN-FLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTK 188
+ I+R++ N FL +E E A +I+++DFG+ + F + +
Sbjct: 78 NGFIHRNVNTQNLFLGNEKDSER----------------AKIIHILDFGLGRPFARYHAR 121
Query: 189 QHIPY----RERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRG-SLPWQGLK 243
++ R G+ RY S N H +EQ R DD+ SL +V G +LPWQ
Sbjct: 122 ENKWIVRIARHSAEFRGSFRYASPNVHLRKEQGRVDDVWSLPYVIIELNGGKALPWQ--- 178
Query: 244 ALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQI 303
+ ++ K L P D+++ ++P + + + SL + Q PD + Q+
Sbjct: 179 ---TDYRRGRVEQMKLNLTPKDVMS-DMPACMDKLMPHLASLNYYQRPDDHMIFKCFWQV 234
Query: 304 MQENGYEEDGHYDW 317
M+ +DW
Sbjct: 235 MENEKITPSSKFDW 248
>CE00873 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 363
Score = 71.6 bits (174), Expect = 2e-12
Identities = 67/284 (23%), Positives = 122/284 (42%), Gaps = 35/284 (12%)
Query: 44 AIKFEPRRSDSPQLRDEFRAYRILNDVRG---IPHAYYFSQEGIHNILIIDLLGPSLEDL 100
A+K EP+ + ++L ++G IP Y N +I+ LL ++ D
Sbjct: 99 AMKIEPKLRAEVITKRMIMEQQVLMKMQGKTHIPTMYASGFNDQFNFIIMQLLSMNVGDF 158
Query: 101 FEWCSR-KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKS 159
+ + S +T +A Q ++ ++ IH+ ++RD+KP N
Sbjct: 159 RKRSPLGRLSKETVGRIAYQTLNALKDIHDMGYVHRDVKPANI----------------- 201
Query: 160 CATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRR 219
C + +++Y++DFG+ ++F+ + IP+R GT RY+S+ H EQ+
Sbjct: 202 CFGVHAQNRHILYLLDFGLVRRFKT-ESGVCIPWRINAGFKGTERYVSVRVHEKLEQTPW 260
Query: 220 DDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYL 279
DD S+ + + + G LPW+ L+ + +E G+ K + T E+ K A L
Sbjct: 261 DDAFSVLYTAYELVVGELPWRYLEDI-----HEIHGVKKLMNEVTK--NGEMFKDIASIL 313
Query: 280 SYCRSLRFDQDP----DYDYLISLMTQIMQENGYEEDGHYDWMD 319
+ + DP Y+ L+ + + E YDW D
Sbjct: 314 VDFHKMILECDPVVELPYEKLLECLKCLYSPKSLLEP--YDWED 355
>CE12416 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 555
Score = 71.2 bits (173), Expect = 3e-12
Identities = 62/243 (25%), Positives = 105/243 (42%), Gaps = 41/243 (16%)
Query: 74 PHAYYFSQEGIHN---ILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEH 130
P A + +GI+ +++ L GP L+ + E + F+ T + + + ++++HE+
Sbjct: 22 PTAIHIYDDGIYKDYRYIVMTLCGPDLQKIAELMNNNFNQDTIIRVCIRTLLAIKTMHEY 81
Query: 131 DLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF--RDPNTK 188
I+RD+KP NF + L +Y+ D+GMA+++ +D K
Sbjct: 82 TYIHRDLKPCNFAVDFNPNSLH------------------VYLFDYGMARKYATKDSGNK 123
Query: 189 QHIPY-RERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLR---GSLPWQGLKA 244
+ R GT RY S+N H +E SR DDL S +F+ L LPW
Sbjct: 124 WQLRRPRNPAQFRGTVRYCSLNMHKRKELSRVDDLWS----WFFMLMEMYAPLPW----- 174
Query: 245 LNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPD----YDYLISLM 300
+ E+I K+ L F + Y S+++ PD YD L + +
Sbjct: 175 -TSSNIPERIEALKEDHLNEYLSKDSFLSSFLPLVEYLNSVQYADRPDYMKIYDILYAKL 233
Query: 301 TQI 303
T+I
Sbjct: 234 TEI 236
>CE02499 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 211
Score = 70.9 bits (172), Expect = 4e-12
Identities = 52/204 (25%), Positives = 94/204 (45%), Gaps = 31/204 (15%)
Query: 35 LNGGSKNPVAIKFEPRRSDSPQLRDEFRAYR---ILNDVRGIPHAYYFSQE--------G 83
L GGS V E + D ++ E+ + + +LN+++ + Y FS + G
Sbjct: 25 LGGGSYGCVHEVIELKTGDRYAMKSEYSSMKKPILLNELKVMKAIYTFSSQHVLKVRDMG 84
Query: 84 IHN---ILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPD 140
+H +I+ +L +++++FE ++ T + Q ++ + +H ++RDIKP+
Sbjct: 85 VHGSTKFIIMQMLEKNMDEVFELLGGSMTLNTAVATSYQCLEGLEFMHWAGFLHRDIKPN 144
Query: 141 NFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLS 200
N+ + +SG IY++D+G+ K+F D N P R+
Sbjct: 145 NYCLD----------------ANSGQGLRTIYIIDYGICKRFVDNNNVIRQP-RKITKFR 187
Query: 201 GTARYMSINTHFGREQSRRDDLES 224
GT + I +H RE SR DLES
Sbjct: 188 GTLDFAPIVSHELREHSRGSDLES 211
>CE01404 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 370
Score = 70.5 bits (171), Expect = 5e-12
Identities = 55/210 (26%), Positives = 93/210 (44%), Gaps = 48/210 (22%)
Query: 88 LIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEF 147
+++ L+GPSLE + R+++ +A Q++D V +HE I+RD+KP N
Sbjct: 78 IVMTLIGPSLESVRRMLKRQYTKSCVINMALQILDAVEVMHEVGFIHRDLKPANI----- 132
Query: 148 QRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQ-FRDPNTKQHIPYRERKSLSGTARYM 206
C + D +++YV+DFG++++ F+ + RER GT ++
Sbjct: 133 ------------CTGTPPQDDHVLYVLDFGISRRVFKSSKCHELRNKRERVPFFGTRKFS 180
Query: 207 SINTHFGREQSRRDDLESLGHV---FFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP 263
S H ++Q R+DD+E+ + F+ RG L W K +KI
Sbjct: 181 SRACHQEKDQGRKDDMETYLYTILDLFHNERG-LSW----------KLDKI--------- 220
Query: 264 TDLLTPEIPKQFAEYLSYCRSLRFDQDPDY 293
IP + Y R L+F+ DY
Sbjct: 221 -------IPSGIDNIIVYLRGLKFEDPVDY 243
>CE16891 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 357
Score = 70.1 bits (170), Expect = 7e-12
Identities = 58/234 (24%), Positives = 102/234 (42%), Gaps = 18/234 (7%)
Query: 85 HNILIIDLLGPSLEDLFE-WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFL 143
+N + I L G SL L + + K +V +A+Q + + +H I+R++ P F
Sbjct: 121 YNWIAITLCGKSLRALRKNQPTGKLTVACGLSVAQQCLKGLEELHRMGFIHRNVAPSVFA 180
Query: 144 ISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTA 203
I + + + D IY++DFG A Q+ + P G+
Sbjct: 181 IGRYTGD-------------NQSDLRNIYILDFGFAHQYMIKDGTLKPPSAHPWKYVGSL 227
Query: 204 RYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP 263
R+M + E SR +DLE ++ ++G LPW LK Y+K L + L+
Sbjct: 228 RHMPRAAYSKVEFSRMEDLEMWFYMSVELVKGCLPWAHLKKPKEVHDYQK--LCRNGLQM 285
Query: 264 TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
++L +P +F + + L F P+Y + L+T + +G + + YDW
Sbjct: 286 REML-GGLPPEFVDIMQIVDKLSFTDTPNYTEIYGLLTNAILFSG-KNEFPYDW 337
>CE18539 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 327
Score = 69.7 bits (169), Expect = 9e-12
Identities = 62/243 (25%), Positives = 102/243 (41%), Gaps = 45/243 (18%)
Query: 88 LIIDLLGPSLEDL-FEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
L+++L+G SL DL + + FS T ++ Q ++ V +H+ I+RD+KP N+
Sbjct: 99 LVMELVGKSLADLKADRPDKVFSFATGLGVSCQCLEAVEELHKTGFIHRDLKPQNY---- 154
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
A + IY++DFG+A+++ + + P RE GT R+
Sbjct: 155 --------------ACGLDEKRHNIYILDFGIARKYLNTKNELKTP-RETVGFKGTVRFA 199
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFL-----RGSLPWQGLKALNNKAKYEKIGLTKQR- 260
I H E +DD ES +FY L LPW+ L + K EK K +
Sbjct: 200 PIACHRNTEMGPKDDCES----WFYLLLDLIVPSGLPWRKLSDKHEVLK-EKEECRKDKR 254
Query: 261 ------LKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGH 314
L+ TD L ++ L Y + DY ++ + + + + D
Sbjct: 255 SSLFAGLRQTDYL--------SKVLDYIDGRAYQDRVDYQFIYKNLAEACKVCNLDIDSP 306
Query: 315 YDW 317
YDW
Sbjct: 307 YDW 309
>CE09897 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 347
Score = 69.7 bits (169), Expect = 9e-12
Identities = 58/234 (24%), Positives = 102/234 (42%), Gaps = 18/234 (7%)
Query: 85 HNILIIDLLGPSLEDLFEWCSR-KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFL 143
+N + I L G SL L + + K +V +A+Q + + +H I+R++ P F
Sbjct: 114 YNWIAITLCGKSLRALRKNQPKGKLTVACGLSVAQQCLKGLEELHRMGFIHRNVAPSVFA 173
Query: 144 ISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTA 203
I + + + D IY++DFG A Q+ + + P G+
Sbjct: 174 IGRYTGD-------------NQSDMRNIYILDFGFAHQYMNKDGTLKPPSAHPWKYVGSL 220
Query: 204 RYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKP 263
R+M E SR +DLE ++ ++G LPW LK Y+K L + L+
Sbjct: 221 RHMPRAAFSKVEFSRMEDLEMWFYMSVELVKGCLPWAHLKKPKEVHDYQK--LCRNGLQM 278
Query: 264 TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
++L +P +F + + L F P+Y + L+T + +G + + YDW
Sbjct: 279 REML-GGLPPEFFDIMQMVDKLSFTDTPNYKEIYGLLTNAILFSG-KNEFPYDW 330
>Hs5454164 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 508
Score = 68.2 bits (165), Expect = 3e-11
Identities = 51/226 (22%), Positives = 98/226 (42%), Gaps = 38/226 (16%)
Query: 85 HNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLI 144
+ ++++ LG L+ + + F T L +M+D + IHE++ ++ D+K N L+
Sbjct: 116 YRFMVMERLGIDLQKI-SGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDVKAANLLL 174
Query: 145 SEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTAR 204
+ + +Y+ D+G++ ++ + RK +GT
Sbjct: 175 GY-------------------KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIE 215
Query: 205 YMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPW-QGLKALNNKAKYEKIGLTKQRLKP 263
+ S++ H G SRR D+E LG+ +L G LPW Q LK + + + +
Sbjct: 216 FTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLK--------DPVAVQTAKTNL 267
Query: 264 TDLLTPEIPK---------QFAEYLSYCRSLRFDQDPDYDYLISLM 300
D L + K + A++L SL +D+ P+Y L ++
Sbjct: 268 LDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKIL 313
>7303521 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 1004
Score = 67.8 bits (164), Expect = 3e-11
Identities = 42/147 (28%), Positives = 73/147 (49%), Gaps = 12/147 (8%)
Query: 171 IYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFF 230
++++DFG+A +F+D + +R++ GT + S + H G SRR DLE LG+
Sbjct: 521 VFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTLEFTSRDAHLG-AHSRRSDLECLGYNLL 579
Query: 231 YFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL-------LTPEIPKQFAEYLSYCR 283
Y+ G LPW K + + + EK+ K+ L TD+ ++PK E+L
Sbjct: 580 YWSEGYLPW---KDVAQQQQQEKVHRAKE-LFMTDVPEMLRQFYGKQVPKYLGEFLLQIG 635
Query: 284 SLRFDQDPDYDYLISLMTQIMQENGYE 310
L + + P+Y+ + + Q GY+
Sbjct: 636 QLAYQERPNYERYRKIFKREYQRLGYD 662
>CE09428 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 394
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 67/254 (26%)
Query: 87 ILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
IL +DLLG +L + E K V LA+QMID + +IH+ +++ DIKP NF
Sbjct: 122 ILQLDLLGLNLLEYAELYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGL 181
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
+++ N + ++DFG+A+ F D + H R GT YM
Sbjct: 182 NEKK------------------NQLNLIDFGLAESFLD-DRGNHREVHNRHYRKGTYVYM 222
Query: 207 SINTH----FGRE------------------------------------------QSRRD 220
S N H FG+ +RRD
Sbjct: 223 SANQHHEQCFGKSFLFAFVSALLIENSAFSKKILLTIPRRKVKPNIFCSNYLITGNTRRD 282
Query: 221 DLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLS 280
D+ESL + L ++ W+ +++NN + KQ + + L P + L
Sbjct: 283 DMESLVYSLRKILDLTMCWKEGRSVNNDDTHRNYFNLKQGNQKSCSLCGIQP--INDMLQ 340
Query: 281 YCRSLRFDQDPDYD 294
CR L F +P+Y+
Sbjct: 341 SCRMLEFKDEPNYE 354
>CE17237 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 550
Score = 63.9 bits (154), Expect = 5e-10
Identities = 65/294 (22%), Positives = 121/294 (41%), Gaps = 46/294 (15%)
Query: 44 AIKFEP-RRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFE 102
A+K E + + L+ E R L+ + E + +++ L G L+ ++
Sbjct: 49 AMKMEKYQEGNESVLKGEVEVLRALSGQKNAIQLLDSGLEPDYRFIVMTLCGMDLQKVYN 108
Query: 103 WCSRKFSVKTTAMLAKQMIDRVRSI---------------HEHDLIYRDIKPDNFLISEF 147
+FS T +A + + V+++ HE I+RD+KP N +
Sbjct: 109 LLKGQFSDSTVLRVAIRSLHAVKAVWEYYFIGTELFRTKLHEACYIHRDLKPCNVTLD-- 166
Query: 148 QRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKS--LSGTARY 205
E S LI+++DFGM +++ + +++ R R + GT RY
Sbjct: 167 YNEYSP----------------LIFLIDFGMGRKYAKIDEGEYVIRRPRDACRFRGTIRY 210
Query: 206 MSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTD 265
S H REQ R DDL + ++ L+ LPW + ++I K
Sbjct: 211 CSPRMHLRREQGRVDDLYAWLYMIVE-LKVELPW------SEVVHPDRIEFLKLEKFDAA 263
Query: 266 LLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMD 319
+ + + K F + + ++LR+ P+Y + L+ ++M + + H D MD
Sbjct: 264 MASNPLTKSFEPIMDHLKTLRYPDRPNYLMIYELLAKMMSDLNAK---HTDPMD 314
>CE20236 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 276
Score = 63.5 bits (153), Expect = 6e-10
Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 24/168 (14%)
Query: 88 LIIDLLGPSLEDLF-EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
L+++L+G SL DL E R FS T +A Q ++ V +H I+RD+KP N+
Sbjct: 99 LVMELVGKSLGDLKNERAERVFSFGTGLGVASQCLEAVEDLHRTGFIHRDLKPQNY---- 154
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYM 206
A + IY++DFG+A+++ + + P RE GT R+
Sbjct: 155 --------------ACGLDEKRHNIYILDFGIARKYLNTKNELKTP-REAVGFKGTVRFA 199
Query: 207 SINTHFGREQSRRDDLESLGHVFF-YFLRGSLPWQGLKALNNKAKYEK 253
+ H E RDD ES ++ L LPW + +N K + K
Sbjct: 200 PLACHRFTELGPRDDCESWFYLLLDLILPRGLPW---RKMNEKGEVLK 244
>CE02965 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 405
Score = 63.5 bits (153), Expect = 6e-10
Identities = 73/311 (23%), Positives = 132/311 (41%), Gaps = 50/311 (16%)
Query: 44 AIKFEPRRSDS--PQLRDEFRAYRILNDVRGIPHAYYFSQEGIH---NILIIDLLGPSLE 98
A+K EP R D + E LN+ RG F G +++++ LLG +L+
Sbjct: 50 AMKVEPNRLDGGPASITKEIEVMMELNN-RGAKFFPIFETGGREPKFHMVVMTLLGENLQ 108
Query: 99 DL-FEWCSRKFSVKTT-AMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSV 156
L + C+ K T + + Q + V+ +H+ +++ D+KP NF+ + L+
Sbjct: 109 VLRMKGCNPKACTPGTWSRIGIQCLFVVKQMHDCGILHHDLKPTNFVWGQSDEALT---- 164
Query: 157 VKSCATSSGGDANLIYVVDFGMAKQF------RDPNTKQHIPYRERK----SLSGTARYM 206
+ Y++DFG++++F N + +R K SL GT +Y
Sbjct: 165 -----------CRVFYLIDFGISRKFIRHVKGTPINQQNGFEFRTEKKKVHSLVGTPKYT 213
Query: 207 SINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDL 266
S H + R DDL SL ++ ++ LPW+ L+A + + TK + K D
Sbjct: 214 SPKAHAMADLGRGDDLWSLMYMIAELVK-PLPWEILEA-------KMLENTKLKSKLKDH 265
Query: 267 LTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMDLNGGQGW 326
+ F + + + F+ P+Y+ + ++ ++G YDW +G
Sbjct: 266 FGMD---GFGKIETMLHACTFNSFPNYEMIYLAFKEVFNKSGVSWLDPYDW------EGK 316
Query: 327 NIKVNKRVNLH 337
N+ KR H
Sbjct: 317 NMPSYKRWRQH 327
>CE29038 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 310
Score = 63.2 bits (152), Expect = 8e-10
Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 29/212 (13%)
Query: 106 RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSG 165
++ + +T Q++ + +H + ++RDIKP N I
Sbjct: 94 KRITDRTLYRAMAQVLKALALVHRAEFLHRDIKPPNCCIG-------------------A 134
Query: 166 GDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESL 225
D IY++D+ + +Q+ D P R L GT RYMS++ H ++ ++DL S
Sbjct: 135 TDCTRIYLIDYVLTRQYLDKCGTVRNP-RPGLGLRGTMRYMSLDAHARQDLGPKNDLVSF 193
Query: 226 GHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRSL 285
+ G LPW K+ N K ++ + ++ L+T + AEY+ SL
Sbjct: 194 LYTTIECGDGCLPWSYEKSEENCIKLKQAHIGEKLCIKKPLMT-----KAAEYI---ESL 245
Query: 286 RFDQDPDYDYLISLMTQIMQENGYEEDGHYDW 317
+ PDY+ L++L+ + + +E Y+W
Sbjct: 246 NYHSIPDYEKLLALIEECNPAD-LKESEPYEW 276
>CE17143 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 338
Score = 61.6 bits (148), Expect = 2e-09
Identities = 47/163 (28%), Positives = 72/163 (43%), Gaps = 29/163 (17%)
Query: 80 SQEGIHN---ILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRD 136
+ +G+ N LI+ L G SLED+ +TA+ R +H ++RD
Sbjct: 81 TDKGVFNGTKFLIMPLFGKSLEDIIGALPGNKCSLSTAI-------GHRVVHWSHYLHRD 133
Query: 137 IKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRER 196
+KP NF + SG D I++VDFGM++++ + + P R R
Sbjct: 134 LKPGNFCVG------------------SGKDIRRIFLVDFGMSRRYCGQDNVIYQP-RTR 174
Query: 197 KSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPW 239
GT Y +H E +R+ DLES G++ G LPW
Sbjct: 175 CQFRGTPVYAPRASHNRAEHNRKSDLESWGYMMIEMTTGKLPW 217
>Hs7705993 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 474
Score = 59.3 bits (142), Expect = 1e-08
Identities = 52/232 (22%), Positives = 101/232 (43%), Gaps = 36/232 (15%)
Query: 85 HNILIIDLLGPSLEDLFEWCSRK-FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFL 143
+ L++ LG SL+ + + S ++ +A +++D + +HE++ ++ ++ +N
Sbjct: 254 YRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENIF 313
Query: 144 ISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRE--RKSLSG 201
+ D + + + +G A FR + +H+ Y E R G
Sbjct: 314 VDP-------------------EDQSQVTLAGYGFA--FRYCPSGKHVAYVEGSRSPHEG 352
Query: 202 TARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL 261
++S++ H G SRR DL+SLG+ +L G LPW N E I KQ+
Sbjct: 353 DLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPW-----TNCLPNTEDIMKQKQKF 407
Query: 262 --KPTDLLTP-----EIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQE 306
KP + P + +YL +L +++ P Y L + + ++Q+
Sbjct: 408 VDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALLQD 459
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 58.9 bits (141), Expect = 2e-08
Identities = 63/256 (24%), Positives = 108/256 (41%), Gaps = 43/256 (16%)
Query: 43 VAIKFEPRRSD--SPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDL 100
+AIK P R S L +E ++ L + + FS+ G I + + G SL L
Sbjct: 706 IAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSAL 765
Query: 101 F--EWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
+W K + +T KQ+++ ++ +H++ +++RDIK DN LI+ +
Sbjct: 766 LRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTY----------- 814
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMS--INTHFGREQ 216
+ ++ + DFG +K+ N P E + +GT +YM+ I R
Sbjct: 815 ---------SGVLKISDFGTSKRLAGIN-----PCTE--TFTGTLQYMAPEIIDKGPRGY 858
Query: 217 SRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFA 276
+ D+ SLG G P+ L +A K+G+ K + PEIP+ +
Sbjct: 859 GKAADIWSLGCTIIEMATGKPPFYELG--EPQAAMFKVGMFK--------VHPEIPESMS 908
Query: 277 EYLSYCRSLRFDQDPD 292
F+ DPD
Sbjct: 909 AEAKAFILKCFEPDPD 924
>CE07205 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 298
Score = 58.2 bits (139), Expect = 3e-08
Identities = 58/255 (22%), Positives = 104/255 (40%), Gaps = 38/255 (14%)
Query: 60 EFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWC---SRKFSVKTTAML 116
E A + V G+P + HN +++DLL LE + C ++KF+ T +
Sbjct: 56 ETLALNAVAGVNGVPRMFATGSTDYHNWIVMDLLSDDLEVII--CRNENKKFAKATGYQI 113
Query: 117 AKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDF 176
Q++ ++ IH +++ DIKP+N ++S + +VDF
Sbjct: 114 LWQVVKILKDIHSKGIVHGDIKPNNLMVSHSSNMFQ------------------LVLVDF 155
Query: 177 GMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTH--FGREQSRRDDLESLGHVFFYFLR 234
G A++F+D N + P S + + I H G +D+ + ++ LR
Sbjct: 156 GCARRFKDVNGNRTPP---APYPSNCIKGLHIPPHSALGMPHMEAEDIMQVAYL-SCLLR 211
Query: 235 GSLPWQGLKALNNKAKYEKIGLTKQR-LKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDY 293
PW+ K + L ++ L+ L P I K A Y +PDY
Sbjct: 212 QYAPWKDDDEFKMTRKKMSLALNPEKFLEEHQDLLPVI-KLLAAQKHYA-------EPDY 263
Query: 294 DYLISLMTQIMQENG 308
++ L+ Q++ +G
Sbjct: 264 IAILDLLQQMLHSSG 278
>CE03487 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 364
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/223 (24%), Positives = 100/223 (44%), Gaps = 32/223 (14%)
Query: 88 LIIDLLGPSLEDLFEWCSR-KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISE 146
L ++ G +L DL + +FSV T+ + + I+ ++ +H ++RD+KP N +
Sbjct: 101 LAMERCGENLSDLRKDTPLGRFSVTTSLFIFYKFIEALQMMHSIGWLHRDVKPANVCVDL 160
Query: 147 FQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQF--RDPNTKQHIPYRERKSLSGTAR 204
R +Y++DFGM+K + +D K R GT R
Sbjct: 161 KSRRH-------------------LYLLDFGMSKIYVEKDGTLKAR---RTSAPFRGTLR 198
Query: 205 YMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRL-KP 263
Y+S+N H ++ SR DD+ S ++ + G LPW+ + K + +K+ RL
Sbjct: 199 YVSVNIHRRQDASRWDDIWSAFYIATENMVGHLPWRRMGDA-MKVEEKKVSSDLSRLIYG 257
Query: 264 TDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQE 306
+D P+ + L+ +S DP Y Y+ +++Q+
Sbjct: 258 SDRSRPKCMEYIENELNNSQS-----DPSYFYVPPAYDKMLQQ 295
>7300559 [T] KOG4279 Serine/threonine protein kinase
Length = 1310
Score = 56.6 bits (135), Expect = 8e-08
Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 31/169 (18%)
Query: 43 VAIKFEPRRS--DSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDL 100
+AIK P ++ D L +E + + L + + S+ G I + + G SL DL
Sbjct: 605 IAIKEVPEKNSQDVQPLHEEIKLHSQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSLSDL 664
Query: 101 FE--WCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
E W K + T A +KQ+++ ++ +HE D+++RDIK DN L++ +
Sbjct: 665 LETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTY----------- 713
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMS 207
+ ++ + DFG +K+ N P E + +GT +YM+
Sbjct: 714 ---------SGVVKISDFGTSKRLARIN-----PMTE--TFTGTLQYMA 746
>CE04290 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 359
Score = 55.1 bits (131), Expect = 2e-07
Identities = 75/327 (22%), Positives = 131/327 (39%), Gaps = 70/327 (21%)
Query: 44 AIKFEPRRSDS--PQLRDEFRAYRILNDVRGIPHAYYFSQEGIH---NILIIDLLGPSLE 98
A+K EP R D + E LN+ RG F G +++++ LLG +L+
Sbjct: 50 AMKVEPNRLDGGPASITKEIEVMMELNN-RGAKFFPIFETGGREPKFHMVVMTLLGENLQ 108
Query: 99 DL-FEWCSRKFSVKTT-AMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSV 156
L + C+ K T + + Q + V+ +H+ ++ D+KP NF+ + L+
Sbjct: 109 VLRMKGCNPKACTPGTWSRIGIQCLFVVKQMHDCGFLHHDLKPANFVWGQSDEVLT---- 164
Query: 157 VKSCATSSGGDANLIYVVDFGMAK-----------------QFRDPNTKQHIPYRERKSL 199
+ + Y++DFG++ +FR N K H SL
Sbjct: 165 -----------SRVFYLIDFGISSKFIRHIKGTPINQQNGFEFRTENKKVH-------SL 206
Query: 200 SGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQ 259
GT +Y S H + R DD SL ++ ++ LPW+ L+A + + TK
Sbjct: 207 VGTPKYTSPKAHAMADLGRGDDFWSLMYMIAELVK-PLPWEILEA-------KMLEKTKL 258
Query: 260 RLKPTDLLTPEIPKQFAEYLSYCRSLRFDQDPDYDYLISLMTQIMQENGYEEDGHYDWMD 319
+ K DL + F + + ++ F P+Y+ + + ++G W D
Sbjct: 259 KSKLKDLYGID---AFGKIETMLQACTFHSFPNYEMIYHAFKDVFTKSG------ASWYD 309
Query: 320 LNGGQGWNIKVNKRVNLHGYGNPTPRN 346
+ G+ K L G+ PRN
Sbjct: 310 HSIGR------EKICRLTNDGDRMPRN 330
>Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 50/199 (25%)
Query: 99 DLFEWCSRKFSVKTTAMLA--KQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSV 156
DL W +K S+ + K M++ V +IH+H +++ D+KP NFLI +
Sbjct: 592 DLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVD---------- 641
Query: 157 VKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARY--------MSI 208
++ ++DFG+A Q + P+T + + S GT Y MS
Sbjct: 642 ------------GMLKLIDFGIANQMQ-PDTTSVV----KDSQVGTVNYMPPEAIKDMSS 684
Query: 209 NTHFGREQSR---RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPT- 264
+ G+ +S+ + D+ SLG + +Y G P+Q + +N +K I + P
Sbjct: 685 SRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQ--QIINQISKLHAI------IDPNH 736
Query: 265 DLLTPEIP-KQFAEYLSYC 282
++ P+IP K + L C
Sbjct: 737 EIEFPDIPEKDLQDVLKCC 755
>Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 54.7 bits (130), Expect = 3e-07
Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 50/199 (25%)
Query: 99 DLFEWCSRKFSVKTTAMLA--KQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSV 156
DL W +K S+ + K M++ V +IH+H +++ D+KP NFLI +
Sbjct: 592 DLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVD---------- 641
Query: 157 VKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARY--------MSI 208
++ ++DFG+A Q + P+T + + S GT Y MS
Sbjct: 642 ------------GMLKLIDFGIANQMQ-PDTTSVV----KDSQVGTVNYMPPEAIKDMSS 684
Query: 209 NTHFGREQSR---RDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPT- 264
+ G+ +S+ + D+ SLG + +Y G P+Q + +N +K I + P
Sbjct: 685 SRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQ--QIINQISKLHAI------IDPNH 736
Query: 265 DLLTPEIP-KQFAEYLSYC 282
++ P+IP K + L C
Sbjct: 737 EIEFPDIPEKDLQDVLKCC 755
>CE02704 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 610
Score = 54.7 bits (130), Expect = 3e-07
Identities = 41/176 (23%), Positives = 76/176 (42%), Gaps = 22/176 (12%)
Query: 73 IPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDL 132
I + Y+ + +II SLE + E ++K + +A ++D + +HE D
Sbjct: 104 IANGYFTYESEKMRYMIIPKYATSLEAVRETNGGTLAMKDSLTVASCILDALEYLHESDY 163
Query: 133 IYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIP 192
+ D+K N L+ + G + +VDFG+A + + K
Sbjct: 164 AHADVKAANILLEK------------------QGVYSTAVLVDFGLAHRTTNNVDKPD-- 203
Query: 193 YRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNK 248
++++ +GT + S + H G S R D+E L + + G+LPW L++ K
Sbjct: 204 --KKRAHNGTCIFTSTDAHRGNNPSFRGDIEILAYNLMMWATGTLPWMALESSPEK 257
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/166 (26%), Positives = 75/166 (44%), Gaps = 34/166 (20%)
Query: 105 SRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSS 164
+++FS + + QM + + +H+ +I+RDIKP+N L+ DG + S
Sbjct: 210 AKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLG------IDGEIKLS----- 258
Query: 165 GGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLES 224
DFG + H P R +L GT Y+ G+E + + DL S
Sbjct: 259 ----------DFGWSV---------HAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWS 299
Query: 225 LGHVFFYFLRGSLPWQGLKALNNKAKYEKIGLTKQRLKPTDLLTPE 270
LG + + FL G+ P++ + + A Y++I K LK + P+
Sbjct: 300 LGVLTYEFLVGAPPFEDMS--GHSATYKRI--AKVDLKIPSFVPPD 341
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 52.8 bits (125), Expect = 1e-06
Identities = 51/214 (23%), Positives = 84/214 (38%), Gaps = 39/214 (18%)
Query: 67 LNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRS 126
L DV+ +P++ + E + G L D + S T + Q+ +R
Sbjct: 71 LYDVQELPNSVFLVMEYCN--------GGDLADYLQ-AKGTLSEDTIRVFLHQIAAAMRI 121
Query: 127 IHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPN 186
+H +I+RD+KP N L+S R S S ++ I + DFG A+
Sbjct: 122 LHSKGIIHRDLKPQNILLSYANRRKSSVSGIR------------IKIADFGFARYLHS-- 167
Query: 187 TKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALN 246
+L G+ YM+ + + DL S+G V + L G P+Q +
Sbjct: 168 ------NMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQD 221
Query: 247 NKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLS 280
+ YEK L P IP++ + YL+
Sbjct: 222 LRMFYEK----------NRSLMPSIPRETSPYLA 245
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/167 (29%), Positives = 70/167 (41%), Gaps = 33/167 (19%)
Query: 77 YYFSQEGIHNILIIDLLGPSLEDLFEWCSRK--FSVKTTAMLAKQMIDRVRSIHEHDLIY 134
Y F EG LI+D L DLF S++ F+ ++ + +H ++Y
Sbjct: 171 YAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVY 227
Query: 135 RDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYR 194
RD+KP+N L+ +DG I V DFG++K+ D K +
Sbjct: 228 RDLKPENILLD------ADGH---------------IKVTDFGLSKEAIDSEKKTY---- 262
Query: 195 ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
S GT YM+ R S D SLG + F L G LP+QG
Sbjct: 263 ---SFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQG 306
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/167 (29%), Positives = 70/167 (41%), Gaps = 33/167 (19%)
Query: 77 YYFSQEGIHNILIIDLLGPSLEDLFEWCSRK--FSVKTTAMLAKQMIDRVRSIHEHDLIY 134
Y F EG LI+D L DLF S++ F+ ++ + +H ++Y
Sbjct: 114 YAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVY 170
Query: 135 RDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYR 194
RD+KP+N L+ +DG I V DFG++K+ D K +
Sbjct: 171 RDLKPENILLD------ADGH---------------IKVTDFGLSKEAIDSEKKTY---- 205
Query: 195 ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
S GT YM+ R S D SLG + F L G LP+QG
Sbjct: 206 ---SFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQG 249
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/206 (26%), Positives = 84/206 (40%), Gaps = 46/206 (22%)
Query: 63 AYRILNDVRGIPHAYYFSQEGIHNILII------DLLG--PSLEDLFEWCSRKFSVKTTA 114
A + LN +GI ++ Q+ ++ D LG L E C+R +
Sbjct: 176 ALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYY------ 229
Query: 115 MLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVV 174
A Q+ID V S+H +I+RDIKP+N L+ + + + +
Sbjct: 230 --ASQIIDAVDSLHNIGIIHRDIKPENILLDKNMK---------------------VKLT 266
Query: 175 DFGMAKQFRD--PNTKQHIP----YRERKSLSGTARYMSINTHFGREQSRRDDLESLGHV 228
DFG AK + NT P Y + KS GTA Y+S R D+ + G +
Sbjct: 267 DFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCI 326
Query: 229 FFYFLRGSLPWQGLKALNNKAKYEKI 254
+ L G P+ KA N ++K+
Sbjct: 327 LYQMLAGKPPF---KAANEYLTFQKV 349
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 12/135 (8%)
Query: 108 FSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATS---S 164
FS + Q+ ++ +H +++RD+KP+N L DG + K +
Sbjct: 231 FSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGDMQKEDEFTLGVG 290
Query: 165 GGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLES 224
GG L+ ++DFG+AK+ R+ NT K+ GT Y++ + S + D+ S
Sbjct: 291 GGGIGLVKLMDFGLAKKLRN-NT--------AKTPCGTIEYVASEVFTSKRYSMKVDMWS 341
Query: 225 LGHVFFYFLRGSLPW 239
+G V F L G P+
Sbjct: 342 IGCVLFTLLCGYPPF 356
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 30/210 (14%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQ--EGIHNILII--DLLGPSLE 98
VA+K + P D RA + + P +F Q E I ++ L G LE
Sbjct: 796 VAVKLIDKLKFPPNKEDLLRAEVQILEKVDHPGVVHFMQMLETTDRIFVVMEKLKGDMLE 855
Query: 99 DLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVK 158
+ + S +TT L Q+++ +R +H ++++ D+KP+N L++ SD VK
Sbjct: 856 MILSSEKGRLSERTTQFLVAQILEALRYLHHLNIVHCDLKPENILLN----SNSDFPQVK 911
Query: 159 SCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSR 218
C DFG A+ + + R+S+ GT Y++ + +R
Sbjct: 912 LC--------------DFGFARIIGEKSF--------RRSVVGTPAYLAPEVLRNKGFNR 949
Query: 219 RDDLESLGHVFFYFLRGSLPWQGLKALNNK 248
D+ S+G + + L G+ P+ + +N++
Sbjct: 950 SLDMWSVGVIVYVSLSGTFPFNEDEDINDQ 979
>CE04444 [T] KOG1164 Casein kinase (serine/threonine/tyrosine protein
kinase)
Length = 299
Score = 52.0 bits (123), Expect = 2e-06
Identities = 60/264 (22%), Positives = 105/264 (39%), Gaps = 52/264 (19%)
Query: 58 RDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRK----FSVKTT 113
R E A L +VRGI Y + IHN ++++ P L+DL R FS T
Sbjct: 55 RRETFALTALAEVRGISRMYDYGATDIHNYIVME---PLLDDLTNIARRNGIKGFSKSTG 111
Query: 114 AMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYV 173
+ Q++ ++ +H + + DIK DN +IS + ++ +
Sbjct: 112 FHILWQLVKILQDVHSFGIAHGDIKADNLMISGSNKTF------------------MLSL 153
Query: 174 VDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFL 233
VDFG+++ F+D N + P + T G+ +DL + ++
Sbjct: 154 VDFGLSRSFKDHNGNRTPPIPFPSGCINLI-HTPARTANGKPHMEAEDLMQVAYL-ACIC 211
Query: 234 RGSLPWQGL---------KALNNKAKYEKIGLTKQRLKPTDLLTPEIPKQFAEYLSYCRS 284
R PW+ + KA K K K Q LKP + I KQ
Sbjct: 212 RKLAPWEDIDGHKMTKLKKAFAEKPK--KFLGEHQDLKP---IIKIIAKQ---------- 256
Query: 285 LRFDQDPDYDYLISLMTQIMQENG 308
+ ++P+Y ++ L+ +++ +G
Sbjct: 257 -KHGKEPNYKEIMDLLQEMLTSSG 279
>At3g53570 [T] KOG0671 LAMMER dual specificity kinases
Length = 467
Score = 51.6 bits (122), Expect = 3e-06
Identities = 48/182 (26%), Positives = 79/182 (43%), Gaps = 27/182 (14%)
Query: 85 HNILIIDLLGPSLEDLFEWCS-RKFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFL 143
H ++ + LGPSL D S R F + L +Q+++ V +H+ LI+ D+KP+N L
Sbjct: 188 HICIVFEKLGPSLYDFLRKNSYRSFPIDLVRELGRQLLESVAYMHDLRLIHTDLKPENIL 247
Query: 144 I--SEF---------QRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIP 192
+ SE+ R DGS K+ SS I ++DFG T +H
Sbjct: 248 LVSSEYIKIPDYKFLSRPTKDGSYFKNLPKSSA-----IKLIDFG-------STTFEH-- 293
Query: 193 YRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYE 252
++ + T Y + G + DL S+G + G +Q + L + A E
Sbjct: 294 -QDHNYIVSTRHYRAPEVILGVGWNYPCDLWSIGCILVELCSGEALFQTHENLEHLAMME 352
Query: 253 KI 254
++
Sbjct: 353 RV 354
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 51.2 bits (121), Expect = 3e-06
Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 33/180 (18%)
Query: 75 HAYYFSQEGIHNILIIDLLGPSLEDLFEWCSRKFSVKTTAMLAKQMIDRVRSIHEHDLIY 134
+AY+ I+ IL G L ++F + +A + + + +HE D+I+
Sbjct: 218 YAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIH 277
Query: 135 RDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYR 194
RDIKP+N L+ G ++ + DFG + H P
Sbjct: 278 RDIKPENLLL---------------------GHKGVLKIADFGWS---------VHEPNS 307
Query: 195 ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKI 254
R +L GT Y+ G+ ++ DL SLG + F L G P+ + N Y+KI
Sbjct: 308 MRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFY---SKNYDETYKKI 364
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 50.8 bits (120), Expect = 4e-06
Identities = 45/167 (26%), Positives = 71/167 (41%), Gaps = 33/167 (19%)
Query: 77 YYFSQEGIHNILIIDLLGPSLEDLFEWCSRK--FSVKTTAMLAKQMIDRVRSIHEHDLIY 134
Y F EG LI+D L D+F S++ F+ + ++ + +H+ ++Y
Sbjct: 140 YAFQTEG-KLYLILDFLRGG--DVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVY 196
Query: 135 RDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYR 194
RD+KP+N L+ E I + DFG++K+ D K +
Sbjct: 197 RDLKPENILLDEIGH---------------------IKLTDFGLSKESVDQEKKAY---- 231
Query: 195 ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
S GT YM+ R S+ D S G + F L G+LP+QG
Sbjct: 232 ---SFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQG 275
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 50.8 bits (120), Expect = 4e-06
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 30/139 (21%)
Query: 119 QMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGM 178
+++ V +HE +++RD+KP+N L+ +DG V+ + DFG+
Sbjct: 240 EIVSAVSHLHEKGIMHRDLKPENILMD------TDGHVM---------------LTDFGL 278
Query: 179 AKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLP 238
AK+F + NT+ + S+ GT YM+ G+ + D S+G + + L G P
Sbjct: 279 AKEFEE-NTRSN-------SMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPP 330
Query: 239 WQGLKA-LNNKAKYEKIGL 256
+ G K + K +KI L
Sbjct: 331 FLGSKGKIQQKIVKDKIKL 349
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 50.4 bits (119), Expect = 6e-06
Identities = 52/207 (25%), Positives = 87/207 (41%), Gaps = 41/207 (19%)
Query: 43 VAIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFS-QEGIHNILIIDLLGPSLE--- 98
VAIK R S S R E + YR +N ++ + H +E + N I ++ LE
Sbjct: 77 VAIKLIKRDSISNDYRKEVKIYREINALKHLSHPNIVKLEEVLQNSRYIGIV---LEYAC 133
Query: 99 --DLFEWCSRKFSVK--TTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDG 154
+ +++ +K +K L Q+I V IH L++RD+K +N L+ +
Sbjct: 134 GGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLENLLLDK-------- 185
Query: 155 SVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGR 214
+ NL+ + DFG +F N K+ G+ Y +
Sbjct: 186 ------------NENLV-ITDFGFVNEFCSRNELM-------KTSCGSPCYAAPELVISA 225
Query: 215 E--QSRRDDLESLGHVFFYFLRGSLPW 239
E ++R+ D+ S G + + L G LPW
Sbjct: 226 EPYEARKADIWSCGVILYAILAGYLPW 252
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 50.4 bits (119), Expect = 6e-06
Identities = 52/196 (26%), Positives = 79/196 (39%), Gaps = 38/196 (19%)
Query: 77 YYFSQEGIHNILIIDLLGPSLEDLFEWCSRK--FSVKTTAMLAKQMIDRVRSIHEHDLIY 134
Y F EG LI+D L DLF S++ F+ + ++ + +H +IY
Sbjct: 135 YAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 191
Query: 135 RDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYR 194
RD+KP+N L+ E I + DFG++K+ D K +
Sbjct: 192 RDLKPENILLDE---------------------EGHIKLTDFGLSKESIDHEKKAY---- 226
Query: 195 ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKI 254
S GT YM+ R ++ D S G + F L G+LP+QG K
Sbjct: 227 ---SFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQG-----KDRKETMT 278
Query: 255 GLTKQRLKPTDLLTPE 270
+ K +L L+PE
Sbjct: 279 MILKAKLGMPQFLSPE 294
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 50.4 bits (119), Expect = 6e-06
Identities = 46/167 (27%), Positives = 71/167 (41%), Gaps = 33/167 (19%)
Query: 77 YYFSQEGIHNILIIDLLGPSLEDLFEWCSRK--FSVKTTAMLAKQMIDRVRSIHEHDLIY 134
Y F EG LI+D L DLF S++ F+ + ++ + +H +IY
Sbjct: 126 YAFQTEG-KLYLILDFLRGG--DLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 182
Query: 135 RDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYR 194
RD+KP+N L+ E I + DFG++K+ D + + +
Sbjct: 183 RDLKPENILLDE---------------------EGHIKITDFGLSKEAIDHDKRAY---- 217
Query: 195 ERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQG 241
S GT YM+ R ++ D S G + F L GSLP+QG
Sbjct: 218 ---SFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQG 261
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 50.1 bits (118), Expect = 7e-06
Identities = 49/215 (22%), Positives = 94/215 (42%), Gaps = 32/215 (14%)
Query: 44 AIKFEPRRSDSPQLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLL--GPSLEDLF 101
A+K RR ++ R E A R+ + + + + +H L+++LL G LE +
Sbjct: 438 AVKILSRRLEANTQR-EVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIR 496
Query: 102 EWCSRKFSVKTTAMLAKQMIDRVRSIHEH-DLIYRDIKPDNFLISEFQRELSDGSVVKSC 160
+ R FS + + + ++ V +HE +++RD+KP+N L ++ + G+ VK
Sbjct: 497 K--KRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADD----TPGAPVK-- 548
Query: 161 ATSSGGDANLIYVVDFGMAK-QFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRR 219
++DFG A+ + + P P T +Y + +
Sbjct: 549 ------------IIDFGFARLRPQSPGVPMQTP-------CFTLQYAAPELLAQQGYDES 589
Query: 220 DDLESLGHVFFYFLRGSLPWQGLKALNNKAKYEKI 254
DL SLG + + L G +P+QG +++ +I
Sbjct: 590 CDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEI 624
>CE29300 [T] KOG0694 Serine/threonine protein kinase
Length = 431
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/216 (22%), Positives = 90/216 (41%), Gaps = 36/216 (16%)
Query: 39 SKNPVAIKFEPRRSDSP-----QLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLL 93
S+ AIK + +R Q++ E R+L I Y Q H ++
Sbjct: 144 SERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYP 203
Query: 94 GPSLEDLFEWCSRKFSVKTTA--MLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQREL 151
S DLF ++ S+ A ++ ++ + +H++D+IYRD+K +N ++ ++ L
Sbjct: 204 TGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHAL 263
Query: 152 SDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTH 211
++DFG+AK+ + ++ ++ GT +YMS +
Sbjct: 264 ---------------------LIDFGLAKKLKQGSS--------TGTICGTLQYMSPDVA 294
Query: 212 FGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNN 247
G S D SLG + L G P+ +A ++
Sbjct: 295 SGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHH 330
>CE29299 [T] KOG0694 Serine/threonine protein kinase
Length = 436
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/216 (22%), Positives = 90/216 (41%), Gaps = 36/216 (16%)
Query: 39 SKNPVAIKFEPRRSDSP-----QLRDEFRAYRILNDVRGIPHAYYFSQEGIHNILIIDLL 93
S+ AIK + +R Q++ E R+L I Y Q H ++
Sbjct: 144 SERKFAIKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYP 203
Query: 94 GPSLEDLFEWCSRKFSVKTTA--MLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQREL 151
S DLF ++ S+ A ++ ++ + +H++D+IYRD+K +N ++ ++ L
Sbjct: 204 TGSTGDLFSVWRQRGSLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHAL 263
Query: 152 SDGSVVKSCATSSGGDANLIYVVDFGMAKQFRDPNTKQHIPYRERKSLSGTARYMSINTH 211
++DFG+AK+ + ++ ++ GT +YMS +
Sbjct: 264 ---------------------LIDFGLAKKLKQGSS--------TGTICGTLQYMSPDVA 294
Query: 212 FGREQSRRDDLESLGHVFFYFLRGSLPWQGLKALNN 247
G S D SLG + L G P+ +A ++
Sbjct: 295 SGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHH 330
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/142 (26%), Positives = 59/142 (40%), Gaps = 27/142 (19%)
Query: 107 KFSVKTTAMLAKQMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGG 166
KF+V + A ++ + IH+ +I+RD+K DN L+ SDG ++
Sbjct: 131 KFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVK------SDGRIM--------- 175
Query: 167 DANLIYVVDFGMAKQFRDPNTKQHIPYRE------RKSLSGTARYMSINTHFGREQSRRD 220
+ DFG +K D Q P E R S GTA +++ G E S
Sbjct: 176 ------LTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFFVTPELLTGSEMSPSS 229
Query: 221 DLESLGHVFFYFLRGSLPWQGL 242
DL + + FL G P+ +
Sbjct: 230 DLWAFSVTLYLFLTGIYPFNDM 251
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 30/139 (21%)
Query: 119 QMIDRVRSIHEHDLIYRDIKPDNFLISEFQRELSDGSVVKSCATSSGGDANLIYVVDFGM 178
+++ V +HE +++RD+KP+N L+ DG V+ + DFG+
Sbjct: 246 EIVSAVSHLHEKGIMHRDLKPENILMD------VDGHVM---------------LTDFGL 284
Query: 179 AKQFRDPNTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLP 238
AK+F + NT+ + S+ GT YM+ G+ + D S+G + + L G P
Sbjct: 285 AKEFEE-NTRSN-------SMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPP 336
Query: 239 WQGLKA-LNNKAKYEKIGL 256
+ G K + K +KI L
Sbjct: 337 FLGSKGKIQQKIVKDKIKL 355
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,968,119
Number of Sequences: 60738
Number of extensions: 1189094
Number of successful extensions: 4706
Number of sequences better than 1.0e-05: 147
Number of HSP's better than 0.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 4314
Number of HSP's gapped (non-prelim): 166
length of query: 473
length of database: 30,389,216
effective HSP length: 110
effective length of query: 363
effective length of database: 23,708,036
effective search space: 8606017068
effective search space used: 8606017068
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)