ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3464 good O KOG0940 Posttranslational modification, protein turnover, chaperones Ubiquitin protein ligase RSP5/NEDD4
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3464 1198133 1200589 819
(819 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 1272 0.0
SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 986 0.0
SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 866 0.0
HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 575 e-163
Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 575 e-163
HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 568 e-161
Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 568 e-161
Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 563 e-160
Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 545 e-155
Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 542 e-154
Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 542 e-154
7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 539 e-153
Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 523 e-148
7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 508 e-143
CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 502 e-142
SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 493 e-139
Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 476 e-134
CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 447 e-125
7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 413 e-115
Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 405 e-112
Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 398 e-110
7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 363 e-100
CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 340 5e-93
SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative up... 339 9e-93
At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 333 8e-91
At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 330 4e-90
YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 325 2e-88
7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 317 5e-86
ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 303 5e-82
Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 286 1e-76
Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 285 2e-76
CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 245 2e-64
Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase 217 7e-56
Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase 217 7e-56
Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase 217 7e-56
7292061 [O] KOG0941 E3 ubiquitin protein ligase 206 1e-52
7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 201 5e-51
At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 198 3e-50
7294742 [O] KOG0941 E3 ubiquitin protein ligase 190 9e-48
Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 189 1e-47
At3g17205 [O] KOG0942 E3 ubiquitin protein ligase 186 1e-46
7291760 [O] KOG0942 E3 ubiquitin protein ligase 181 3e-45
Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase 178 3e-44
Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase 173 8e-43
SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase 173 1e-42
CE19147 [O] KOG4427 E3 ubiquitin protein ligase 173 1e-42
At3g53090 [O] KOG4427 E3 ubiquitin protein ligase 172 1e-42
ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase 172 2e-42
YJR036c [O] KOG0941 E3 ubiquitin protein ligase 171 3e-42
SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase 168 4e-41
7295004 [O] KOG4427 E3 ubiquitin protein ligase 164 5e-40
Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase 164 7e-40
YGL141w [O] KOG0942 E3 ubiquitin protein ligase 160 1e-38
CE29116 [O] KOG0941 E3 ubiquitin protein ligase 159 2e-38
Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase 155 3e-37
CE15744 [O] KOG0942 E3 ubiquitin protein ligase 154 7e-37
Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase 144 7e-34
Hs4557026 [S] KOG1426 FOG: RCC1 domain 142 3e-33
Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase 141 4e-33
Hs4758520 [S] KOG1426 FOG: RCC1 domain 107 7e-23
Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase 105 2e-22
Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperp... 105 4e-22
At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase 104 5e-22
CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplas... 100 7e-21
YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase 97 1e-19
7297647 [R] KOG4276 Predicted hormone receptor interactor 93 2e-18
Hs15300020 [R] KOG4276 Predicted hormone receptor interactor 88 5e-17
SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase 86 2e-16
Hs13375805 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 86 2e-16
At4g38600 [O] KOG0170 E3 ubiquitin protein ligase 84 1e-15
Hs18860882 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 74 7e-13
Hs7706523 [Q] KOG1208 Dehydrogenases with different specificitie... 74 1e-12
Hs18860886 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 74 1e-12
Hs18860884 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 74 1e-12
Hs18860880 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 74 1e-12
Hs13699258 [Q] KOG1208 Dehydrogenases with different specificiti... 74 1e-12
Hs9257195 [R] KOG3209 WW domain-containing protein 73 2e-12
CE17508 [R] KOG4276 Predicted hormone receptor interactor 70 1e-11
7291247 [R] KOG3209 WW domain-containing protein 68 6e-11
Hs6912462 [R] KOG3209 WW domain-containing protein 62 3e-09
Hs13346498 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 60 2e-08
Hs17433806_2 [R] KOG3209 WW domain-containing protein 59 2e-08
Hs11141889_2 [R] KOG1891 Proline binding protein WW45 59 2e-08
Hs7661612 [O] KOG0941 E3 ubiquitin protein ligase 55 4e-07
CE03201 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 54 7e-07
7297326 [Q] KOG1208 Dehydrogenases with different specificities ... 54 1e-06
7291734 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 54 1e-06
At3g59770 [I] KOG1888 Putative phosphoinositide phosphatase 54 1e-06
Hs14043024_1 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 54 1e-06
CE06034 [R] KOG3209 WW domain-containing protein 53 2e-06
>YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 809
Score = 1272 bits (3292), Expect = 0.0
Identities = 630/830 (75%), Positives = 672/830 (80%), Gaps = 36/830 (4%)
Query: 2 SISVKLVAAESLNRRDVFRSPDPFAVLTIDGSQTKSTAAAKKTLNPYWNEVFQFKNVSEN 61
SISVKLVAAESL +RDVFRSPDPFAVLTIDG QTKST+AAKKTLNPYWNE F+F +++EN
Sbjct: 4 SISVKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKTLNPYWNETFKFDDINEN 63
Query: 62 SILTXXXXXXXXXXXXXXGFLGVVNVRIGDILGHLDEDTATSNGRAREETITRDLKRSND 121
SILT GFLGVVNVR+GD+LGHLDEDTATS+GR REETITRDLK+SND
Sbjct: 64 SILTIQVFDQKKFKKKDQGFLGVVNVRVGDVLGHLDEDTATSSGRPREETITRDLKKSND 123
Query: 122 GLSVSGRIILVLTVLPXXX-------XXXXXXXXXXXXXXXXXXXXQSDSMTNASTIDNR 174
G++VSGR+I+VL+ LP S + ++++ +R
Sbjct: 124 GMAVSGRLIVVLSKLPSSSPHSQAPSGHTASSSTNTSSTTRTNGHSTSSTRNHSTSHPSR 183
Query: 175 LIAQTVANNLQTTTLDNQDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXF 234
AQ V + LQ+ T F
Sbjct: 184 GTAQAVESTLQSGT-------------------TAATNTATTSHRSTNSTSSATRQYSSF 224
Query: 235 EDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQR-----VNTELERRQH 289
EDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQ+E +R NTELERRQH
Sbjct: 225 EDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQTEAERGNQLNANTELERRQH 284
Query: 290 RGRTLPDGGAQSEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQ 349
RGRTLP G S +S+V V G GS P VN LGELP GWEQ
Sbjct: 285 RGRTLPGGS-----SDNSSVTVQVGGGSNIPPVNGAAAAAFAATGGTTSGLGELPSGWEQ 339
Query: 350 RFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTN 409
RFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGP+ TIQQQPVSQLGPLPSGWEMRLTN
Sbjct: 340 RFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPTNTTIQQQPVSQLGPLPSGWEMRLTN 399
Query: 410 TARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIRV 469
TARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHI+V
Sbjct: 400 TARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIKV 459
Query: 470 RRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLF 529
RRKNIFED+YQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLF
Sbjct: 460 RRKNIFEDAYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLF 519
Query: 530 EYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKV 589
EYSA+DNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKV
Sbjct: 520 EYSAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKV 579
Query: 590 VLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDEN 649
VLQDMEGVD+EVYNSL W+LENSIDG+LDLTF+ DDERFGE+V VDLKP+GR IEVTD N
Sbjct: 580 VLQDMEGVDAEVYNSLNWMLENSIDGVLDLTFSADDERFGEVVTVDLKPDGRNIEVTDGN 639
Query: 650 KKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDW 709
KKEYVELYTQWRI DRVQEQFKAFMDGFNEL+PEDLV VFDERELELLIGGIAEID+EDW
Sbjct: 640 KKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDW 699
Query: 710 KKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRR 769
KKHTDYRGYQESDEVIQWFWKC++EWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRR
Sbjct: 700 KKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRR 759
Query: 770 FTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
FTIEKAGEVQQLPKSHTCFNRVDLP Y DY+S KQKLTLAVEETIGFGQE
Sbjct: 760 FTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIGFGQE 809
>SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 767
Score = 986 bits (2548), Expect = 0.0
Identities = 494/818 (60%), Positives = 579/818 (70%), Gaps = 61/818 (7%)
Query: 3 ISVKLVAAESLNRRDVFRSPDPFAVLTIDGSQTKSTAAAKKTLNPYWNEVFQFKNVSENS 62
I V +VAA+ L +RDVFR PDPFAVLT+DG QT +T A KKTLNPYWNE F+ NV++NS
Sbjct: 10 IRVTIVAADGLYKRDVFRFPDPFAVLTVDGEQTHTTTAIKKTLNPYWNETFEV-NVTDNS 68
Query: 63 ILTXXXXXXXXXXXXXXGFLGVVNVRIGDILGHLDEDTATSNGRAREETITRDLKRSNDG 122
+ GFLGV+N+R+GD+L D A +E +TRDLK+SN+
Sbjct: 69 TIAIQVFDQKKFKKKGQGFLGVINLRVGDVL-----DLAIGG----DEMLTRDLKKSNEN 119
Query: 123 LSVSGRIILVLTVLPXXXXXXXXXXXXXXXXXXXXXXXQSDSMTNASTIDNRLIAQTVAN 182
V G+II+ L S T ST+ A + A
Sbjct: 120 TVVHGKIIINL------------------------------STTAQSTLQVPSSAASGAR 149
Query: 183 NLQTTTLDNQDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFEDQYGRLP 242
Q T++ N FEDQYGRLP
Sbjct: 150 T-QRTSITNDPQSSQSSSVSRNPASSRAGSPTRDNAPAASPASSEPRTFSSFEDQYGRLP 208
Query: 243 PGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQSE 302
PGWERRTDN GRTYYVDHNTR+TTW RP L ++ A
Sbjct: 209 PGWERRTDNLGRTYYVDHNTRSTTWIRPNLS-------------------SVAGAAAAEL 249
Query: 303 GSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFVDH 362
SS+S+ V G + GELPPGWEQR+TPEGR YFVDH
Sbjct: 250 HSSASSANVTEGVQPSSSNAARRTEASVLTSNATTAGSGELPPGWEQRYTPEGRPYFVDH 309
Query: 363 NTRTTTWVDPRRQQYIRTYG-PSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTK 421
NTRTTTWVDPRRQQYIR+YG P+ TIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTK
Sbjct: 310 NTRTTTWVDPRRQQYIRSYGGPNNATIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTK 369
Query: 422 TTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDSYQE 481
TTTWDDPRLPSSLDQNVPQYKRDFRRK+IYF SQPAL LPGQCHI+VRR +IFEDSY E
Sbjct: 370 TTTWDDPRLPSSLDQNVPQYKRDFRRKLIYFLSQPALHPLPGQCHIKVRRNHIFEDSYAE 429
Query: 482 IMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQI 541
IMRQ+ DLKKRLMIKFDGE+GLDYGG+SRE+FFLLSHEMFNPFYCLFEYS+ DNYT+QI
Sbjct: 430 IMRQSATDLKKRLMIKFDGEDGLDYGGLSREYFFLLSHEMFNPFYCLFEYSSVDNYTLQI 489
Query: 542 NPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEV 601
NP+SGINPEHLNYFKFIGRV+GL +FHRRF+DAFFV + YKM+L+KKV LQDME +D+E
Sbjct: 490 NPHSGINPEHLNYFKFIGRVIGLAIFHRRFVDAFFVVSFYKMILQKKVTLQDMESMDAEY 549
Query: 602 YNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWR 661
Y SL WIL+N I G+LDLTF+V+D FGE+V +DLKPNGR IEVT+ENK+EYV+L T WR
Sbjct: 550 YRSLVWILDNDITGVLDLTFSVEDNCFGEVVTIDLKPNGRNIEVTEENKREYVDLVTVWR 609
Query: 662 IADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQES 721
I R++EQF AF +GF+EL+P++L+NVFDERELELLIGGI+EID+EDWKKHTDYR Y E+
Sbjct: 610 IQKRIEEQFNAFHEGFSELIPQELINVFDERELELLIGGISEIDMEDWKKHTDYRSYSEN 669
Query: 722 DEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQL 781
D++I+WFW+ + EW NE+++RLLQFTTGTSRIPVNGFKDLQGSDGPR+FTIEKAGE +L
Sbjct: 670 DQIIKWFWELMDEWSNEKKSRLLQFTTGTSRIPVNGFKDLQGSDGPRKFTIEKAGEPNKL 729
Query: 782 PKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
PK+HTCFNR+DLPPYT + KL++AVEETIGFGQE
Sbjct: 730 PKAHTCFNRLDLPPYTSKKDLDHKLSIAVEETIGFGQE 767
>SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 786
Score = 866 bits (2238), Expect = 0.0
Identities = 444/821 (54%), Positives = 543/821 (66%), Gaps = 54/821 (6%)
Query: 7 LVAAESLNRRDVFRSPDPFAVLTIDGSQTKSTAAAKKTLNPYWNEVFQFKNVSENSILTX 66
+VAA+ L++RD+FR PDPFA+LT+DG QT +T KK++NPYWNE F+ V +S+++
Sbjct: 12 IVAADGLSKRDLFRQPDPFAILTVDGEQTHTTKVIKKSVNPYWNEGFEV-TVKPSSVISI 70
Query: 67 XXXXXXXXXXXXXGFLGVVNVRIGDILGHLDEDTATSNGRAREETITRDLKRSND-GLSV 125
GFLG+V+ R+ ++ + SN RE ++TR LK+S+ LSV
Sbjct: 71 RLFDQKKFKKKDQGFLGLVSFRMREV------GSFRSN---REVSLTRPLKKSSTTNLSV 121
Query: 126 SGRIILVLTVLPXXXXXXXXXXXXXXXXXXXXXXXQSDSMTNASTIDNRLIAQTVANNLQ 185
G LVL V P + + T +T R A T +N
Sbjct: 122 LGN--LVLKVAPSKIRAPAGNHSSTTANRTTSTPTTTTARTTRTT--PRPTATTNTSNQS 177
Query: 186 TTTLDNQDXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXFEDQYGR 240
T+ FEDQYGR
Sbjct: 178 TSNSTRNGTSAATSNGTGTGAGTGASHRSSPVTNRQTNNTSALSNSNAHIMSSFEDQYGR 237
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWERR D+ GRTYYVDHNTRTTTW RP + V +++ +R H+ R LPD
Sbjct: 238 LPPGWERRADSLGRTYYVDHNTRTTTWTRPASSTNPVHNTSSDSQRLNHQNRHLPDDSNP 297
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
S S S +LP GWE R+T GR YFV
Sbjct: 298 SLMQSDSG--------------------------------NDLPFGWEMRYTDTGRPYFV 325
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPST--NTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDH 418
DHNTRTTTWVDPR G ST + +Q Q +S LGPLPSGWEMRLTN+ARVYFVDH
Sbjct: 326 DHNTRTTTWVDPRNPLVRPNGGSSTVGSLMQPQSLSHLGPLPSGWEMRLTNSARVYFVDH 385
Query: 419 NTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDS 478
NTKTTTWDDPRLPS+LDQ+VPQYK DFRRK+IYFRSQP +R LPGQC+++VRR +IFEDS
Sbjct: 386 NTKTTTWDDPRLPSALDQDVPQYKCDFRRKLIYFRSQPGMRPLPGQCNVKVRRDHIFEDS 445
Query: 479 YQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYT 538
Y EIMR + DLKKRLMI+FDGE+GLDYGG+SREFFFLLSH+MF+P YCLFEYSA DNYT
Sbjct: 446 YAEIMRYSAHDLKKRLMIRFDGEDGLDYGGLSREFFFLLSHKMFDPIYCLFEYSAVDNYT 505
Query: 539 IQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVD 598
+QINP+S INPEHLNYF+FIGRV+GL +FHRRFLDAFFV +LYK +LRKKV L DME +D
Sbjct: 506 LQINPHSSINPEHLNYFRFIGRVIGLAIFHRRFLDAFFVVSLYKKLLRKKVSLADMESID 565
Query: 599 SEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYT 658
+E Y SLKW+LEN I GILDLTF+V+++ FGE+ V+L NG IEVT+ENKK+YV+L T
Sbjct: 566 AEFYRSLKWVLENDITGILDLTFSVEEDHFGEVRTVELITNGENIEVTEENKKKYVDLVT 625
Query: 659 QWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGY 718
+WR++ RV++QF AF GF ELV DLVNVFDERELELLIGGI+++DVEDWK HT+YR Y
Sbjct: 626 EWRVSKRVEQQFNAFYSGFVELVSPDLVNVFDERELELLIGGISDVDVEDWKSHTEYRTY 685
Query: 719 QESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEV 778
+D VI+WFW+ I W NE R++LLQF TGTSRIPVNGF+DLQGSDGPR+FTIEKAG
Sbjct: 686 IATDPVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNGFRDLQGSDGPRKFTIEKAGTP 745
Query: 779 QQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
QLP +HTCFNR+DLP Y ++ +KL+LAVE T+GFG E
Sbjct: 746 DQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAVENTVGFGNE 786
>HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 854
Score = 575 bits (1482), Expect = e-163
Identities = 301/598 (50%), Positives = 393/598 (65%), Gaps = 35/598 (5%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSE-------VQRVNTELERRQHRGRT 293
LP GWE R D GRTYYV+HN RTTTW RP + +E N +E + R R+
Sbjct: 266 LPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRS 325
Query: 294 LPDG----GAQSEGSSSSNV---AVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPG 346
L A EG+ S V T + Q+P + LPPG
Sbjct: 326 LSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSF----LPPG 381
Query: 347 WEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMR 406
WE R P GR +F+DHNT+TTTW DPR + + ++ + LGPLP GWE R
Sbjct: 382 WEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLN-----PNDLGPLPPGWEER 436
Query: 407 LTNTARVYFVDHNTKTTTWDDPRL--PSSLDQNVPQYKRDFRRKVIYFRSQ---PALRIL 461
+ R +++DHN+K T W+DPRL P+ VP Y R+F++K YFR + PA +
Sbjct: 437 IHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVP-YSREFKQKYDYFRKKLKKPA--DI 493
Query: 462 PGQCHIRVRRKNIFEDSYQEIMR-QTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHE 520
P + +++ R NIFE+SY+ IM + P+ LK RL I+F+ E+GLDYGGV+RE+FFLLS E
Sbjct: 494 PNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKE 553
Query: 521 MFNPFYCLFEYSAHDNYTIQINPNSGI-NPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGA 579
MFNP+Y LFEYSA DNYT+QINPNSG+ N +HL+YF FIGRV GL VFH + LD FF+
Sbjct: 554 MFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRP 613
Query: 580 LYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPN 639
YKMML K++ L DME VDSE YNSLKWILEN LDL F +D+E FG+ VDLKPN
Sbjct: 614 FYKMMLGKQITLNDMESVDSEYYNSLKWILENDPTE-LDLMFCIDEENFGQTYQVDLKPN 672
Query: 640 GREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIG 699
G EI VT+ENK+EY++L QWR +RVQ+Q AF++GF EL+P DL+ +FDE ELELL+
Sbjct: 673 GSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMC 732
Query: 700 GIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGF 758
G+ ++DV DW++H+ Y+ GY + VIQWFWK + D E+R RLLQF TGTSR+P+NGF
Sbjct: 733 GLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGF 792
Query: 759 KDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
+L GS+GP+ FTIE+ G ++LP++HTCFNR+DLPPY +E ++KL +AVE GF
Sbjct: 793 AELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGF 850
Score = 66.6 bits (161), Expect = 1e-10
Identities = 31/75 (41%), Positives = 42/75 (55%), Gaps = 6/75 (8%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTL------DQSEVQRVNTELERRQHRGRTL 294
LPPGWE + DN GRTYYV+HN RTT W RP+L + ++++N E R+ R R
Sbjct: 74 LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRH 133
Query: 295 PDGGAQSEGSSSSNV 309
+ E S +V
Sbjct: 134 ISEDLEPEPSEGGDV 148
>Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 955
Score = 575 bits (1482), Expect = e-163
Identities = 301/598 (50%), Positives = 393/598 (65%), Gaps = 35/598 (5%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSE-------VQRVNTELERRQHRGRT 293
LP GWE R D GRTYYV+HN RTTTW RP + +E N +E + R R+
Sbjct: 367 LPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRS 426
Query: 294 LPDG----GAQSEGSSSSNV---AVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPG 346
L A EG+ S V T + Q+P + LPPG
Sbjct: 427 LSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSF----LPPG 482
Query: 347 WEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMR 406
WE R P GR +F+DHNT+TTTW DPR + + ++ + LGPLP GWE R
Sbjct: 483 WEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLN-----PNDLGPLPPGWEER 537
Query: 407 LTNTARVYFVDHNTKTTTWDDPRL--PSSLDQNVPQYKRDFRRKVIYFRSQ---PALRIL 461
+ R +++DHN+K T W+DPRL P+ VP Y R+F++K YFR + PA +
Sbjct: 538 IHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVP-YSREFKQKYDYFRKKLKKPA--DI 594
Query: 462 PGQCHIRVRRKNIFEDSYQEIMR-QTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHE 520
P + +++ R NIFE+SY+ IM + P+ LK RL I+F+ E+GLDYGGV+RE+FFLLS E
Sbjct: 595 PNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKE 654
Query: 521 MFNPFYCLFEYSAHDNYTIQINPNSGI-NPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGA 579
MFNP+Y LFEYSA DNYT+QINPNSG+ N +HL+YF FIGRV GL VFH + LD FF+
Sbjct: 655 MFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRP 714
Query: 580 LYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPN 639
YKMML K++ L DME VDSE YNSLKWILEN LDL F +D+E FG+ VDLKPN
Sbjct: 715 FYKMMLGKQITLNDMESVDSEYYNSLKWILENDPTE-LDLMFCIDEENFGQTYQVDLKPN 773
Query: 640 GREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIG 699
G EI VT+ENK+EY++L QWR +RVQ+Q AF++GF EL+P DL+ +FDE ELELL+
Sbjct: 774 GSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMC 833
Query: 700 GIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGF 758
G+ ++DV DW++H+ Y+ GY + VIQWFWK + D E+R RLLQF TGTSR+P+NGF
Sbjct: 834 GLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGF 893
Query: 759 KDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
+L GS+GP+ FTIE+ G ++LP++HTCFNR+DLPPY +E ++KL +AVE GF
Sbjct: 894 AELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGF 951
Score = 84.7 bits (208), Expect = 5e-16
Identities = 62/220 (28%), Positives = 90/220 (40%), Gaps = 50/220 (22%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTL------DQSEVQRVNTELERRQHRGRTL 294
LPPGWE + DN GRTYYV+HN RTT W RP+L + ++++N E R+ R R
Sbjct: 195 LPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRH 254
Query: 295 PDGGAQSEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPE 354
+ E S +V T S+ + L P R +P+
Sbjct: 255 ISEDLEPEPSEGGDVPEPWETISEEVNI---------AGDSLGLALPPPPASPGSRTSPQ 305
Query: 355 GRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGP---------------- 398
+ + + T D +Q+ ++ IQ++P S+L
Sbjct: 306 ELSEELSRRLQITP--DSNGEQF-------SSLIQREPSSRLRSCSVTDAVAEQGHLPPP 356
Query: 399 ----------LPSGWEMRLTNTARVYFVDHNTKTTTWDDP 428
LPSGWE R R Y+V+HN +TTTW P
Sbjct: 357 SVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRP 396
>HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 862
Score = 568 bits (1463), Expect = e-161
Identities = 288/582 (49%), Positives = 367/582 (62%), Gaps = 41/582 (7%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWERR DN GR YYVDH TRTTTW+RPTL+ S +L+R Q +G
Sbjct: 319 LPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLE-SVRNYEQWQLQRSQLQGAMQQFNQRF 377
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
G+ LG LPPGWE+R GR YFV
Sbjct: 378 IYGNQD---------------------LFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFV 416
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
+HNTR T W DPR Q + PLP GWEMR T YFVDHN
Sbjct: 417 NHNTRITQWEDPRSQGQLNEK----------------PLPEGWEMRFTVDGIPYFVDHNR 460
Query: 421 KTTTWDDPRLPSSLDQNVPQ--YKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDS 478
+TTT+ DPR S N PQ Y RDF+ KV YFR +P I V RK +FEDS
Sbjct: 461 RTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDS 520
Query: 479 YQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYT 538
+Q+IM +P+DL++RL + F GEEGLDYGGV+RE+FFLLSHE+ NP YCLFEY+ DNY
Sbjct: 521 FQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYC 580
Query: 539 IQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVD 598
+QINP S INP+HL YF+FIGR + + +FH +F+D F YK +L K V L+D+E +D
Sbjct: 581 LQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESID 640
Query: 599 SEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELY 657
E YNSL W+ EN+I+ L++ F+VD E GE+ DLKPNG I VT+ENK+EY+ +
Sbjct: 641 PEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMV 700
Query: 658 TQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRG 717
+WR++ V+EQ +AF +GFNE++P+ + FD +ELE+L+ G+ EID+ DW++H YR
Sbjct: 701 AEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRH 760
Query: 718 YQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGE 777
Y + + I WFW+ + E DNE+R RLLQF TGT R+PV GF DL GS+GP++F IEK G+
Sbjct: 761 YARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGK 820
Query: 778 VQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
LP+SHTCFNR+DLPPY YE K+KL A+EET GFGQE
Sbjct: 821 ENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE 862
Score = 81.3 bits (199), Expect = 6e-15
Identities = 48/144 (33%), Positives = 63/144 (43%), Gaps = 30/144 (20%)
Query: 295 PDGGAQSEGSSSSNVA-VHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGE-----LPPGWE 348
P ++S+GSS+ ++ +T T + A + L LPPGWE
Sbjct: 233 PSATSESDGSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWE 292
Query: 349 QRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLT 408
QR GR Y+VDH + TTW P PLP GWE R+
Sbjct: 293 QRVDQHGRVYYVDHVEKRTTWDRPE------------------------PLPPGWERRVD 328
Query: 409 NTARVYFVDHNTKTTTWDDPRLPS 432
N R+Y+VDH T+TTTW P L S
Sbjct: 329 NMGRIYYVDHFTRTTTWQRPTLES 352
Score = 56.2 bits (134), Expect = 2e-07
Identities = 22/35 (62%), Positives = 27/35 (76%)
Query: 236 DQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRP 270
D G LPPGWE+RTD+ GR Y+V+HNTR T W+ P
Sbjct: 394 DPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDP 428
>Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 903
Score = 568 bits (1463), Expect = e-161
Identities = 288/582 (49%), Positives = 367/582 (62%), Gaps = 41/582 (7%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWERR DN GR YYVDH TRTTTW+RPTL+ S +L+R Q +G
Sbjct: 360 LPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLE-SVRNYEQWQLQRSQLQGAMQQFNQRF 418
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
G+ LG LPPGWE+R GR YFV
Sbjct: 419 IYGNQD---------------------LFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFV 457
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
+HNTR T W DPR Q + PLP GWEMR T YFVDHN
Sbjct: 458 NHNTRITQWEDPRSQGQLNEK----------------PLPEGWEMRFTVDGIPYFVDHNR 501
Query: 421 KTTTWDDPRLPSSLDQNVPQ--YKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDS 478
+TTT+ DPR S N PQ Y RDF+ KV YFR +P I V RK +FEDS
Sbjct: 502 RTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDS 561
Query: 479 YQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYT 538
+Q+IM +P+DL++RL + F GEEGLDYGGV+RE+FFLLSHE+ NP YCLFEY+ DNY
Sbjct: 562 FQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYC 621
Query: 539 IQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVD 598
+QINP S INP+HL YF+FIGR + + +FH +F+D F YK +L K V L+D+E +D
Sbjct: 622 LQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESID 681
Query: 599 SEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELY 657
E YNSL W+ EN+I+ L++ F+VD E GE+ DLKPNG I VT+ENK+EY+ +
Sbjct: 682 PEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMV 741
Query: 658 TQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRG 717
+WR++ V+EQ +AF +GFNE++P+ + FD +ELE+L+ G+ EID+ DW++H YR
Sbjct: 742 AEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRH 801
Query: 718 YQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGE 777
Y + + I WFW+ + E DNE+R RLLQF TGT R+PV GF DL GS+GP++F IEK G+
Sbjct: 802 YARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGK 861
Query: 778 VQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
LP+SHTCFNR+DLPPY YE K+KL A+EET GFGQE
Sbjct: 862 ENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE 903
Score = 81.3 bits (199), Expect = 6e-15
Identities = 48/144 (33%), Positives = 63/144 (43%), Gaps = 30/144 (20%)
Query: 295 PDGGAQSEGSSSSNVA-VHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGE-----LPPGWE 348
P ++S+GSS+ ++ +T T + A + L LPPGWE
Sbjct: 274 PSATSESDGSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWE 333
Query: 349 QRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLT 408
QR GR Y+VDH + TTW P PLP GWE R+
Sbjct: 334 QRVDQHGRVYYVDHVEKRTTWDRPE------------------------PLPPGWERRVD 369
Query: 409 NTARVYFVDHNTKTTTWDDPRLPS 432
N R+Y+VDH T+TTTW P L S
Sbjct: 370 NMGRIYYVDHFTRTTTWQRPTLES 393
Score = 56.2 bits (134), Expect = 2e-07
Identities = 22/35 (62%), Positives = 27/35 (76%)
Query: 236 DQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRP 270
D G LPPGWE+RTD+ GR Y+V+HNTR T W+ P
Sbjct: 435 DPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDP 469
>Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 900
Score = 563 bits (1451), Expect = e-160
Identities = 286/581 (49%), Positives = 384/581 (65%), Gaps = 39/581 (6%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWE + D GR+YYVDHN+RTTTW +PT+ Q+ V+ ++L Q G Q
Sbjct: 350 LPPGWEEKQDERGRSYYVDHNSRTTTWTKPTV-QATVE--TSQLTSSQS------SAGPQ 400
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
S+ S+S + G Q + G LP GWE R P GR +F+
Sbjct: 401 SQASTSDS-------GQQVTQPSEIEQ-------------GFLPKGWEVRHAPNGRPFFI 440
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
DHNT+TTTW DPR + G ++ + LGPLP GWE R R+++++HN
Sbjct: 441 DHNTKTTTWEDPRLKIPAHLRGKTSLDTS----NDLGPLPPGWEERTHTDGRIFYINHNI 496
Query: 421 KTTTWDDPRLPS-SLDQNVPQYKRDFRRKVIYFRSQ-PALRILPGQCHIRVRRKNIFEDS 478
K T W+DPRL + ++ Y RD++RK +FR + +P + +++RR + EDS
Sbjct: 497 KRTQWEDPRLENVAITGPAVPYSRDYKRKYEFFRRKLKKQNDIPNKFEMKLRRATVLEDS 556
Query: 479 YQEIMRQTPED-LKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNY 537
Y+ IM D LK RL I+FDGE+GLDYGGV+RE+FFL+S EMFNP+Y LFEYSA DNY
Sbjct: 557 YRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNY 616
Query: 538 TIQINPNSGI-NPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEG 596
T+QINPNSG+ N +HL+YFKFIGRV G+ V+H + LD FF+ YKMML K + L DME
Sbjct: 617 TLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMES 676
Query: 597 VDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVEL 656
VDSE YNSL+WILEN LDL F +D+E FG+ +LK G EI VT++NKKEY+ L
Sbjct: 677 VDSEYYNSLRWILENDPTE-LDLRFIIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYL 735
Query: 657 YTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYR 716
QWR +R+Q+Q AF +GF EL+P+DL+ +FDE ELELL+ G+ ++DV DW++HT Y+
Sbjct: 736 VIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYK 795
Query: 717 -GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKA 775
GY + +VIQWFWK + D+E+R RLLQF TGTSR+P+NGF +L GS+GP+ FT+E+
Sbjct: 796 NGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQW 855
Query: 776 GEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
G ++LP++HTCFNR+DLPPY +E KL +A+E T GF
Sbjct: 856 GTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAIENTQGF 896
Score = 75.1 bits (183), Expect = 4e-13
Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 25/207 (12%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWE R D GRTYYV+H +R T WKRPT + N ++ + R T
Sbjct: 193 LPPGWEERQDILGRTYYVNHESRRTQWKRPTPQDNLTDAENGNIQLQAQRAFT------- 245
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
+ ++ T + + PP P A
Sbjct: 246 ----TRRQISEETESVDNRESSENWEIIREDEATMYSNQAFPSPPPSSNLDVPTHLA--E 299
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTN-------TIQQQPVSQL-----GPLPSGWEMRLT 408
+ N R T + + Q + S+ T ++QP + LP GWE +
Sbjct: 300 ELNARLTIFGNSAVSQPASSSNHSSRRGSLQAYTFEEQPTLPVLLPTSSGLPPGWEEKQD 359
Query: 409 NTARVYFVDHNTKTTTWDDPRLPSSLD 435
R Y+VDHN++TTTW P + ++++
Sbjct: 360 ERGRSYYVDHNSRTTTWTKPTVQATVE 386
>Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 922
Score = 545 bits (1405), Expect = e-155
Identities = 283/583 (48%), Positives = 372/583 (63%), Gaps = 47/583 (8%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWERR D+ R YYVDHNTRTTTW+RPT++ N E + Q Q
Sbjct: 383 LPPGWERRVDDRRRVYYVDHNTRTTTWQRPTMESVR----NFEQWQSQRN---------Q 429
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
+G+ + + S A N G LPPGWE+R R YFV
Sbjct: 430 LQGAMQQFNQRYLYSASMLAAENDPY--------------GPLPPGWEKRVDSTDRVYFV 475
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
+HNT+TT W DPR T +Q + PLP GWE+R T YFVDHNT
Sbjct: 476 NHNTKTTQWEDPR-----------TQGLQNEE-----PLPEGWEIRYTREGVRYFVDHNT 519
Query: 421 KTTTWDDPRL-PSSLDQNVPQ--YKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFED 477
+TTT+ DPR SS+ + PQ Y+R FR K+ +FR LP I V R+ +FED
Sbjct: 520 RTTTFKDPRNGKSSVTKGGPQIAYERGFRWKLAHFRYLCQSNALPSHVKINVSRQTLFED 579
Query: 478 SYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNY 537
S+Q+IM P DL++RL + F GEEGLDYGG++RE+FFLLSHE+ NP YCLFEY+ +NY
Sbjct: 580 SFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNY 639
Query: 538 TIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGV 597
+QINP S INP+HL+YF FIGR + + +FH +F+D F YK ML KK+ ++D+E +
Sbjct: 640 CLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESI 699
Query: 598 DSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVEL 656
D+E YNSL WI +N+I+ L++ F+VD E G++ DLK G I VT+ENK EY+ L
Sbjct: 700 DTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGL 759
Query: 657 YTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYR 716
T+WR + VQEQ KAF+DGFNE+VP + FDE+ELE+++ G+ E+D+ DW+++T YR
Sbjct: 760 MTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYR 819
Query: 717 GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAG 776
Y + + I WFW+ + E DNE R RLLQF TGT R+P+ GF +L GS+GP++F IEK G
Sbjct: 820 HYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVG 879
Query: 777 EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
+ LP+SHTCFNR+DLPPY YE K+KL A+EET GFGQE
Sbjct: 880 KDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE 922
Score = 56.2 bits (134), Expect = 2e-07
Identities = 21/35 (60%), Positives = 27/35 (77%)
Query: 236 DQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRP 270
D YG LPPGWE+R D+ R Y+V+HNT+TT W+ P
Sbjct: 453 DPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDP 487
Score = 54.3 bits (129), Expect = 7e-07
Identities = 29/64 (45%), Positives = 37/64 (57%), Gaps = 6/64 (9%)
Query: 389 QQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPR-LPSSLDQNVPQYKRDFRR 447
QQ + LPSGWE R R Y+VDHNT+TTTW+ P+ LP ++ V D RR
Sbjct: 341 QQSGNANTETLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRV-----DDRR 395
Query: 448 KVIY 451
+V Y
Sbjct: 396 RVYY 399
>Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 542 bits (1397), Expect = e-154
Identities = 283/583 (48%), Positives = 363/583 (61%), Gaps = 48/583 (8%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWE+RTD GR YYVDHNTRTTTW+RPT + E+ Q + L GA
Sbjct: 332 LPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVR------NYEQWQSQRNQLQ--GAM 383
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
S + + P LG LPPGWE+R GR Y+V
Sbjct: 384 QHFSQRFLYQFWSASTDHDP-------------------LGPLPPGWEKR-QDNGRVYYV 423
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
+HNTRTT W DPR Q I Q+P LP GWEM+ T+ YFVDHNT
Sbjct: 424 NHNTRTTQWEDPRTQGMI-----------QEPA-----LPPGWEMKYTSEGVRYFVDHNT 467
Query: 421 KTTTWDDPR--LPSSLDQNVP-QYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFED 477
+TTT+ DPR S Q P Y R FR K FR LP I V R+ +FED
Sbjct: 468 RTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFED 527
Query: 478 SYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNY 537
S+Q+IM P DL++RL I GEEGLDYGG++RE+FFLLSHE+ NP YCLFEY+ +NY
Sbjct: 528 SFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNY 587
Query: 538 TIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGV 597
+QINP S INP+HL YF+FIGR + + ++H +F+D F YK ML K+ L+D+E +
Sbjct: 588 CLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESI 647
Query: 598 DSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVEL 656
D E YNS+ WI EN+++ L+L F D E G++ +LK G I VT+ENK+EY+ L
Sbjct: 648 DPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIML 707
Query: 657 YTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYR 716
T WR V+EQ KAF+DGFNE+ P + + FDE+ELEL++ G+ EID+ DW+K T YR
Sbjct: 708 LTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYR 767
Query: 717 GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAG 776
Y ++ + IQWFW+ + E DNE+R RLLQF TGT R+PV GF +L GS+GP++F I+K G
Sbjct: 768 HYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVG 827
Query: 777 EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
+ LP+SHTCFNR+DLPPY YE ++KL A+EET GFGQE
Sbjct: 828 KETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEGFGQE 870
Score = 80.1 bits (196), Expect = 1e-14
Identities = 39/86 (45%), Positives = 43/86 (49%), Gaps = 26/86 (30%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LP GWEQR P GR Y+VDHNT+TTTW P LP G
Sbjct: 302 LPAGWEQRELPNGRVYYVDHNTKTTTWERP--------------------------LPPG 335
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDP 428
WE R R Y+VDHNT+TTTW P
Sbjct: 336 WEKRTDPRGRFYYVDHNTRTTTWQRP 361
Score = 59.3 bits (142), Expect = 2e-08
Identities = 28/51 (54%), Positives = 33/51 (63%), Gaps = 2/51 (3%)
Query: 383 PSTNTIQQQPVSQLGP--LPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLP 431
PST+ QQ P + P LP+GWE R RVY+VDHNTKTTTW+ P P
Sbjct: 284 PSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPP 334
Score = 56.2 bits (134), Expect = 2e-07
Identities = 24/35 (68%), Positives = 27/35 (76%), Gaps = 1/35 (2%)
Query: 236 DQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRP 270
D G LPPGWE+R DN GR YYV+HNTRTT W+ P
Sbjct: 402 DPLGPLPPGWEKRQDN-GRVYYVNHNTRTTQWEDP 435
>Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 542 bits (1397), Expect = e-154
Identities = 283/583 (48%), Positives = 363/583 (61%), Gaps = 48/583 (8%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWE+RTD GR YYVDHNTRTTTW+RPT + E+ Q + L GA
Sbjct: 332 LPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVR------NYEQWQSQRNQLQ--GAM 383
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
S + + P LG LPPGWE+R GR Y+V
Sbjct: 384 QHFSQRFLYQSSSASTDHDP-------------------LGPLPPGWEKR-QDNGRVYYV 423
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
+HNTRTT W DPR Q I Q+P LP GWEM+ T+ YFVDHNT
Sbjct: 424 NHNTRTTQWEDPRTQGMI-----------QEPA-----LPPGWEMKYTSEGVRYFVDHNT 467
Query: 421 KTTTWDDPR--LPSSLDQNVP-QYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFED 477
+TTT+ DPR S Q P Y R FR K FR LP I V R+ +FED
Sbjct: 468 RTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFED 527
Query: 478 SYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNY 537
S+Q+IM P DL++RL I GEEGLDYGG++RE+FFLLSHE+ NP YCLFEY+ +NY
Sbjct: 528 SFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNY 587
Query: 538 TIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGV 597
+QINP S INP+HL YF+FIGR + + ++H +F+D F YK ML K+ L+D+E +
Sbjct: 588 CLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESI 647
Query: 598 DSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVEL 656
D E YNS+ WI EN+++ L+L F D E G++ +LK G I VT+ENK+EY+ L
Sbjct: 648 DPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIML 707
Query: 657 YTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYR 716
T WR V+EQ KAF+DGFNE+ P + + FDE+ELEL++ G+ EID+ DW+K T YR
Sbjct: 708 LTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYR 767
Query: 717 GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAG 776
Y ++ + IQWFW+ + E DNE+R RLLQF TGT R+PV GF +L GS+GP++F I+K G
Sbjct: 768 HYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVG 827
Query: 777 EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
+ LP+SHTCFNR+DLPPY YE ++KL A+EET GFGQE
Sbjct: 828 KETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEGFGQE 870
Score = 80.1 bits (196), Expect = 1e-14
Identities = 39/86 (45%), Positives = 43/86 (49%), Gaps = 26/86 (30%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LP GWEQR P GR Y+VDHNT+TTTW P LP G
Sbjct: 302 LPAGWEQRELPNGRVYYVDHNTKTTTWERP--------------------------LPPG 335
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDP 428
WE R R Y+VDHNT+TTTW P
Sbjct: 336 WEKRTDPRGRFYYVDHNTRTTTWQRP 361
Score = 59.3 bits (142), Expect = 2e-08
Identities = 28/51 (54%), Positives = 33/51 (63%), Gaps = 2/51 (3%)
Query: 383 PSTNTIQQQPVSQLGP--LPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLP 431
PST+ QQ P + P LP+GWE R RVY+VDHNTKTTTW+ P P
Sbjct: 284 PSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPP 334
Score = 56.2 bits (134), Expect = 2e-07
Identities = 24/35 (68%), Positives = 27/35 (76%), Gaps = 1/35 (2%)
Query: 236 DQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRP 270
D G LPPGWE+R DN GR YYV+HNTRTT W+ P
Sbjct: 402 DPLGPLPPGWEKRQDN-GRVYYVNHNTRTTQWEDP 435
>7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 949
Score = 539 bits (1388), Expect = e-153
Identities = 277/585 (47%), Positives = 368/585 (62%), Gaps = 38/585 (6%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LPPGWE R D GR YYVDHNTR TTW+RP ++ L QH G +
Sbjct: 397 LPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSER---------LMHFQHWQ------GQR 441
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
+ S N Q P LG LP GWE++ + R YFV
Sbjct: 442 AHVVSQGNQRYLYSQQQQQPTA-----VTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFV 496
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
+H RTT W DPR Q G + I + GPLP GWE+R T +FVDHNT
Sbjct: 497 NHKNRTTQWEDPRTQ------GQEVSLINE------GPLPPGWEIRYTAAGERFFVDHNT 544
Query: 421 KTTTWDDPR--LPSSLD--QNVPQ-YKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIF 475
+ TT++DPR P VP+ Y+R FR K+ FR LP I V R+ +F
Sbjct: 545 RRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLF 604
Query: 476 EDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHD 535
EDSY +IMR +L++RL I F GEEGLDYGGVSRE+FFLLSHE+ NP YCLFEY+ +
Sbjct: 605 EDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKN 664
Query: 536 NYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDME 595
NY++QINP S +NP+HL YFKFIGR + + ++H RF+ + F YK ML KK+ ++D+E
Sbjct: 665 NYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIE 724
Query: 596 GVDSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYV 654
+D E YNSL W+ +N+ID L+L F+VD E G+++ +LK NG + VT+ENK+EY+
Sbjct: 725 TIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYI 784
Query: 655 ELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTD 714
L T+WR+ +++Q K F++GFNE+VP + + FDERELEL++ G+ ++DVEDW+++T
Sbjct: 785 TLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTI 844
Query: 715 YRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEK 774
YR Y + + + WFW+ + E DNE+RARLLQF TGT R+PV GF +L GS+GP+RF IEK
Sbjct: 845 YRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEK 904
Query: 775 AGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
G+ LP+SHTCFNR+DLPPY Y+ +KLT A+EET GF QE
Sbjct: 905 VGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE 949
Score = 75.1 bits (183), Expect = 4e-13
Identities = 37/86 (43%), Positives = 42/86 (48%), Gaps = 24/86 (27%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LP GWE R GR Y+VDHNTR+T W P PLP G
Sbjct: 365 LPAGWEIRLDQYGRRYYVDHNTRSTYWEKPT------------------------PLPPG 400
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDP 428
WE+R RVY+VDHNT+ TTW P
Sbjct: 401 WEIRKDGRGRVYYVDHNTRKTTWQRP 426
Score = 50.8 bits (120), Expect = 8e-06
Identities = 27/65 (41%), Positives = 38/65 (57%), Gaps = 7/65 (10%)
Query: 388 IQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPR-LPSSLDQNVPQYKRDFR 446
+Q QP PLP+GWE+RL R Y+VDHNT++T W+ P LP + ++D R
Sbjct: 355 LQTQPADD-EPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGW-----EIRKDGR 408
Query: 447 RKVIY 451
+V Y
Sbjct: 409 GRVYY 413
>Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 748
Score = 523 bits (1346), Expect = e-148
Identities = 272/608 (44%), Positives = 360/608 (58%), Gaps = 47/608 (7%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LP GWE R GR Y++H TRTT W+RPT SE L +
Sbjct: 159 LPDGWEERRTASGRIQYLNHITRTTQWERPTRPASEYSSPGRPLSCFVDENTPISGTNGA 218
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFV 360
+ G SS SQ +LP G+EQR T +G+ YF+
Sbjct: 219 TCGQSSDPRLAERRVRSQR--------HRNYMSRTHLHTPPDLPEGYEQRTTQQGQVYFL 270
Query: 361 DHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNT 420
T +TW DPR + + +LGPLP GWE+R T T RVYFVDHN
Sbjct: 271 HTQTGVSTWHDPRVPRDLSNIN----------CEELGPLPPGWEIRNTATGRVYFVDHNN 320
Query: 421 KTTTWDDPRLPSSL-----------DQN----------------VPQYKRDFRRKVIYFR 453
+TT + DPRL ++L DQ VP+YKRD +K+ R
Sbjct: 321 RTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVSLCPDDTECLTVPRYKRDLVQKLKILR 380
Query: 454 SQPALRI-LPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSRE 512
+ + + G C I V R+ IFE+SY+++M+ P+DL KRLMIKF GEEGLDYGGV+RE
Sbjct: 381 QELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVARE 440
Query: 513 FFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFL 572
+ +LLSHEM NP+Y LF+YS D YT+QINP+S +NPEHL+YF F+GR++G+ VFH ++
Sbjct: 441 WLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYI 500
Query: 573 DAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELV 632
D F YK +L K + L DME VD +++NSL WILEN I G+LD TF V+ +GE++
Sbjct: 501 DGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGEII 560
Query: 633 VVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDER 692
+LKPNG+ I V +ENKKEYV LY WR ++ QF A GFNE++P+ L+ FDE+
Sbjct: 561 QHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEK 620
Query: 693 ELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSR 752
ELEL+I G+ +IDV DWK +T + +++WFWK + +D E+RARLLQF TG+SR
Sbjct: 621 ELELIICGLGKIDVNDWKVNTRLKHCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSR 680
Query: 753 IPVNGFKDLQGSDGPRRFTIEKAGE-VQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVE 811
+P+ GFK LQG+ GPR FTI + LPK+HTCFNR+D+PPY YE +KL A+E
Sbjct: 681 VPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIE 740
Query: 812 ETIGFGQE 819
ET GF E
Sbjct: 741 ETCGFAVE 748
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/88 (31%), Positives = 45/88 (50%), Gaps = 1/88 (1%)
Query: 1 MSISVKLVAAESLNRRDVFRSPDPFAVLTIDGS-QTKSTAAAKKTLNPYWNEVFQFKNVS 59
+ + + ++ A++L ++D FR PDPFA + +DGS Q ST K TL+P WN+ +
Sbjct: 12 VKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPKWNQHYDLYIGK 71
Query: 60 ENSILTXXXXXXXXXXXXXXGFLGVVNV 87
+S+ GFLG V +
Sbjct: 72 SDSVTISVWNHKKIHKKQGAGFLGCVRL 99
>7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1082
Score = 508 bits (1307), Expect = e-143
Identities = 250/480 (52%), Positives = 336/480 (69%), Gaps = 13/480 (2%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LPP W + P GR +F+DH +R TTW+DPR + P N ++ LGPLP G
Sbjct: 606 LPPRWSMQVAPNGRTFFIDHASRRTTWIDPRNGRA----SPMPNQTRRVE-DDLGPLPEG 660
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDPRL--PSSLDQNVPQYKRDFRRKVIYFRSQPALRI 460
WE R+ RV+++DHNT+TT W+DPRL P+ Q VP Y RD+++K YF+S
Sbjct: 661 WEERVHTDGRVFYIDHNTRTTQWEDPRLSNPNIAGQAVP-YSRDYKQKYEYFKSHIRKPT 719
Query: 461 -LPGQCHIRVRRKNIFEDSYQEIMRQTPEDL-KKRLMIKFDGEEGLDYGGVSREFFFLLS 518
+P + IR+RR +I EDSY+ I T DL K +L ++F+GE GLDYGG++RE+F+LLS
Sbjct: 720 NVPNKFEIRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGETGLDYGGLAREWFYLLS 779
Query: 519 HEMFNPFYCLFEYSAHDNYTIQINPNSGI-NPEHLNYFKFIGRVVGLGVFHRRFLDAFFV 577
EMFNP+Y LFEYSA DNYT+QIN SG+ N EHL+YFKFIGR+ G+ V+H + LDAFF+
Sbjct: 780 KEMFNPYYGLFEYSAMDNYTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDAFFI 839
Query: 578 GALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLK 637
YKMML+K + L+DME VD+E YNSL WI EN IL+LTF +D++ FG+ +LK
Sbjct: 840 RPFYKMMLQKPIDLKDMESVDTEYYNSLMWIKEND-PRILELTFCLDEDVFGQKSQHELK 898
Query: 638 PNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELL 697
P G I+VT+ENK EY++L +WR RV+EQ +F+DGF ++P +L+ +FDE ELELL
Sbjct: 899 PGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELL 958
Query: 698 IGGIAEIDVEDWKKHTDYRG-YQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVN 756
+ GI IDV+DW+++T Y+G Y + +IQWFW+ + + NE R+RLLQF TGTSR+P+N
Sbjct: 959 MCGIQNIDVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMN 1018
Query: 757 GFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
GFK+L GS+GP+ FTIEK G P++HTCFNR+DLPPY Y K KL A+E + GF
Sbjct: 1019 GFKELYGSNGPQMFTIEKWGTPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKAIEGSQGF 1078
Score = 55.5 bits (132), Expect = 3e-07
Identities = 22/43 (51%), Positives = 26/43 (60%)
Query: 235 EDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEV 277
ED G LP GWE R GR +Y+DHNTRTT W+ P L +
Sbjct: 651 EDDLGPLPEGWEERVHTDGRVFYIDHNTRTTQWEDPRLSNPNI 693
Score = 55.1 bits (131), Expect = 4e-07
Identities = 26/54 (48%), Positives = 33/54 (60%), Gaps = 5/54 (9%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTL-----DQSEVQRVNTELERRQH 289
LP GWE R D GRTYYV+H RTT W RPT+ QS ++ ++ +RR H
Sbjct: 248 LPAGWEERQDANGRTYYVNHTARTTQWDRPTVLNSHSSQSTDDQLASDFQRRFH 301
>CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 817
Score = 502 bits (1293), Expect = e-142
Identities = 270/609 (44%), Positives = 354/609 (57%), Gaps = 76/609 (12%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQ 300
LP GWE R D GR YYVDHNTRTTTW+RPT D E E+ Q G Q
Sbjct: 255 LPQGWEMRRDPRGRVYYVDHNTRTTTWQRPTADMLEAH------EQWQ-------SGRDQ 301
Query: 301 SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPE-GRAYF 359
+ + S LG LP GWE+R P R YF
Sbjct: 302 AMLQWEQRFLLQQNNFSADDP------------------LGPLPEGWEKRQDPNTSRMYF 343
Query: 360 VDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHN 419
V+H RTT W DPR Q + + P LP GWEMR T +F+DH
Sbjct: 344 VNHVNRTTQWEDPRTQGFRGSDQP---------------LPDGWEMRFTEQGVPFFIDHQ 388
Query: 420 TKTTTWDDPRL-----PSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNI 474
+KTTT++DPR P + ++ FR K+ FR +P I V R N+
Sbjct: 389 SKTTTYNDPRTGKPVGPLGVVGVQMAMEKSFRWKIAQFRYLCLSNSVPNHVKITVSRNNV 448
Query: 475 FEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAH 534
FEDS+QEIMR+ DL++RL I+F GEEGLDYGGV+RE+FFLLSHE+ NP YCLF Y+ +
Sbjct: 449 FEDSFQEIMRKNAVDLRRRLYIQFRGEEGLDYGGVAREWFFLLSHEVLNPMYCLFMYAGN 508
Query: 535 DNYTIQINPNSGINPEHLNYFKFIGRVVGL-----------------------GVFHRRF 571
+NY++QINP S +NP+HL YF++IGR + + +FH +F
Sbjct: 509 NNYSLQINPASFVNPDHLKYFEYIGRFIAMLKKPGNFDDLKFSDQYISFSPKNALFHGKF 568
Query: 572 LDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGI-LDLTFNVDDERFGE 630
+ + F YK ML KK+VL+D+E VDSE+YNSL WI +N+ID ++L F D E GE
Sbjct: 569 IYSGFTMPFYKKMLNKKIVLKDIEQVDSEIYNSLMWIKDNNIDECDMELYFVADYELLGE 628
Query: 631 LVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFD 690
L +LK G EI VT+ENK EY+EL +WR V++Q KAF GFN + P + + FD
Sbjct: 629 LKTYELKEGGTEIAVTEENKLEYIELLVEWRFNRGVEQQTKAFFTGFNSVFPLEWMQYFD 688
Query: 691 ERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGT 750
ERELELL+ G+ ++DV+DW+++T YR Y + + WFW+ + D E+RARLLQF TGT
Sbjct: 689 ERELELLLCGMQDVDVDDWQRNTVYRHYAPQSKQVTWFWQWVRSLDQEKRARLLQFVTGT 748
Query: 751 SRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAV 810
R+PV GF +L GS GP+ F IE+ G+ LP+SHTCFNR+DLPPY Y+ +KL++A+
Sbjct: 749 CRVPVGGFSELMGSTGPQLFCIERVGKENWLPRSHTCFNRLDLPPYRSYDQLVEKLSMAI 808
Query: 811 EETIGFGQE 819
E T GFG E
Sbjct: 809 EMTEGFGNE 817
Score = 89.7 bits (221), Expect = 2e-17
Identities = 64/201 (31%), Positives = 84/201 (40%), Gaps = 45/201 (22%)
Query: 283 ELERRQHRGRTLPDGGAQSEGSSSSNVAVHTGTGSQTPAV---NXXXXXXXXXXXXXXXX 339
E +RR R A SE S+S+ VA T + ++ PA +
Sbjct: 151 ERKRRSAGVRAETAASASSEASTSNGVA--TSSSARRPATAKRDTLAAPTSTAAAAAAAT 208
Query: 340 LG---------ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQ 390
G +LP GWE RF GR Y+VDH T++TTW P Q
Sbjct: 209 AGGTPAAGAEEQLPDGWEMRFDQYGRKYYVDHTTKSTTWERPSTQ--------------- 253
Query: 391 QPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDP---------RLPSSLDQNVPQY 441
PLP GWEMR RVY+VDHNT+TTTW P + S DQ + Q+
Sbjct: 254 -------PLPQGWEMRRDPRGRVYYVDHNTRTTTWQRPTADMLEAHEQWQSGRDQAMLQW 306
Query: 442 KRDFRRKVIYFRSQPALRILP 462
++ F + F + L LP
Sbjct: 307 EQRFLLQQNNFSADDPLGPLP 327
>SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 671
Score = 493 bits (1270), Expect = e-139
Identities = 222/451 (49%), Positives = 320/451 (70%), Gaps = 7/451 (1%)
Query: 376 QYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPR----LP 431
+++ + P +++QQ + GPLP+GWEMRL+ VYFVDH+TKTTTW DPR
Sbjct: 221 KHLLEHYPLALSVRQQVAVEKGPLPAGWEMRLSEDYHVYFVDHSTKTTTWSDPRDNVVAS 280
Query: 432 SSLDQN---VPQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDSYQEIMRQTPE 488
S+ +N + Q +++RK+ Y +P + + Q ++V R FED+Y I + +
Sbjct: 281 DSVSENTDSIQQINDEYQRKIAYMYDRPEMAVNDAQLQLKVSRATTFEDAYDIISKLSVS 340
Query: 489 DLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGIN 548
D+KK+L+I+F E+GLDYGGVSREFF++LSH +FNP Y LFEY+ DNY +QI+P S +N
Sbjct: 341 DMKKKLLIRFRNEDGLDYGGVSREFFYILSHAIFNPGYSLFEYATDDNYGLQISPLSSVN 400
Query: 549 PEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWI 608
P+ +YF+F+GRV+GL ++HRR+LD FV YK +L+K + L+D++ VD Y SLKWI
Sbjct: 401 PDFRSYFRFVGRVMGLAIYHRRYLDVQFVLPFYKRILQKPLCLEDVKDVDEVYYESLKWI 460
Query: 609 LENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQE 668
N +D L L F+V++ RFGE V VDL PNGR I V ++NK Y++ T+ ++ +E
Sbjct: 461 KNNDVDESLCLNFSVEENRFGESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEE 520
Query: 669 QFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWF 728
QF A G NEL+P+ ++ +F+E EL+ L+ G +IDV+DWK+ TDYR Y E+D+++ WF
Sbjct: 521 QFNALKGGLNELIPDSVLQIFNENELDTLLNGKRDIDVQDWKRFTDYRSYTETDDIVIWF 580
Query: 729 WKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCF 788
W+ ++EW E++A+LLQF TGTSR+P++GFKD+ GSDGPR+FTIEK G + QLPK+HTCF
Sbjct: 581 WELLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEKVGHISQLPKAHTCF 640
Query: 789 NRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
NR+D+PPY E +QKLT+A++ET GFG E
Sbjct: 641 NRLDIPPYNSKEELEQKLTIAIQETAGFGTE 671
>Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 757
Score = 476 bits (1226), Expect = e-134
Identities = 239/523 (45%), Positives = 328/523 (62%), Gaps = 45/523 (8%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPR----------------RQQYIRTYGPST 385
ELP G+EQR T +G+ YF+ T +TW DPR + ++ +
Sbjct: 235 ELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPSPSGTIPGGDAAFLYEFLLQGHTSEP 294
Query: 386 NTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSL----------- 434
+ +LGPLP GWE+R T + R+YFVDHN +TT + DPRL +
Sbjct: 295 RDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQ 354
Query: 435 -----------DQNVP--QYKRDFRRKVIYFRSQPALRI-LPGQCHIRVRRKNIFEDSYQ 480
D+ +P +Y+RD +K+ R + +L+ G C I V R+ IFE+SY+
Sbjct: 355 PLPLPSEGSLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYR 414
Query: 481 EIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQ 540
+IM+ P+DLKKRLM+KF GEEGLDYGGV+RE+ +LL HEM NP+Y LF+YS + Y +Q
Sbjct: 415 QIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQ 474
Query: 541 INPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSE 600
INP+S INP+HL+YF F+GR++GL VFH +++ F YK +L K + L D+E VD E
Sbjct: 475 INPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPE 534
Query: 601 VYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQW 660
++ SL WILEN I +LD TF V+ FG ++ +LKPNGR + VT+ENKKEYV LY W
Sbjct: 535 LHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNW 594
Query: 661 RIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQE 720
R ++ QF A GFNEL+P+ L+ FD++ELEL+IGG+ +ID+ DWK +T +
Sbjct: 595 RFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVA 654
Query: 721 SDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSD---GPRRFTIEKA-G 776
+++WFW+ + +D E+RARLLQF TG++R+P+ GFK LQGS GPR FTI
Sbjct: 655 DSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDA 714
Query: 777 EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
LPK+HTCFNR+D+PPY YE +KL AVEET GF E
Sbjct: 715 NTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE 757
Score = 54.3 bits (129), Expect = 7e-07
Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 1 MSISVKLVAAESLNRRDVFRSPDPFAVLTIDGS-QTKSTAAAKKTLNPYWNEVFQFKNVS 59
+ I + ++ A++L ++D FR PDPFA + +DGS Q ST K TL+P WN+ +
Sbjct: 13 IKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDPKWNQHYDLYVGK 72
Query: 60 ENSILTXXXXXXXXXXXXXXGFLGVVNV 87
+SI GFLG V +
Sbjct: 73 TDSITISVWNHKKIHKKQGAGFLGCVRL 100
>CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 810
Score = 447 bits (1151), Expect = e-125
Identities = 229/515 (44%), Positives = 319/515 (61%), Gaps = 73/515 (14%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LP GW+ + P GR +F+DH T+TTTW DPR R ++ + ++G LP+G
Sbjct: 318 LPDGWDMQVAPNGRTFFIDHRTKTTTWTDPRPGAATRV-----PLLRGKTDDEIGALPAG 372
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDPRLPS-SLDQNVPQYKRDFRRKVIYFRSQ-PALRI 460
WE R+ RV+F+DHN + T W+DPR + ++ Y RD++RKV Y RS+ P
Sbjct: 373 WEQRVHADGRVFFIDHNRRRTQWEDPRFENENIAGPAVPYSRDYKRKVEYLRSRLPKPNS 432
Query: 461 LPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHE 520
G+C + V R +FEDSY+ IM + DL+ +L I+F GE GLDYGGV+RE+FFLLSH+
Sbjct: 433 NSGKCDMVVHRDTLFEDSYRHIMDKKDYDLRNKLWIEFFGETGLDYGGVTREWFFLLSHQ 492
Query: 521 MFNPFYCLFEYSA----------------------------------------HDNYTIQ 540
+FNP+Y LFEYSA DNYT+Q
Sbjct: 493 IFNPYYGLFEYSATPFFWAIKCFLKLYKPTKKWRNFQILVINSNKQFLKKKNYRDNYTLQ 552
Query: 541 INPNS-GINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDS 599
INP+S NPEHL+YF FIGR++G+ ++H + LDAFF+ YKMML KK+ L DME VD+
Sbjct: 553 INPHSEACNPEHLSYFHFIGRIIGMAIYHGKLLDAFFIRPFYKMMLGKKITLFDMESVDN 612
Query: 600 EVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQ 659
E YNSL ++ +N L+LTF++DD FGE ++L PNG + VT++NK+EY+E
Sbjct: 613 EYYNSLIYVKDND-PADLELTFSLDDSIFGETQNIELIPNGANVPVTEDNKEEYIEA--- 668
Query: 660 WRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRG-Y 718
+VP +L+ +FD ELELL+ G+ +IDV+DWK +T Y+G Y
Sbjct: 669 --------------------VVPSNLLRLFDANELELLMCGLQKIDVKDWKANTIYKGGY 708
Query: 719 QESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEV 778
S +V+ FWKCI +DNE RAR+LQF +GTSR+P+NGF++L GS+G ++FTIE+ G
Sbjct: 709 GPSSQVVHNFWKCILSFDNEMRARVLQFVSGTSRVPMNGFRELYGSNGLQKFTIERWGSA 768
Query: 779 QQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEET 813
LP++HTCFNR+DLPPYT ++ K KL A+E +
Sbjct: 769 DMLPRAHTCFNRLDLPPYTTFKELKSKLLTAIENS 803
>7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1017
Score = 413 bits (1062), Expect = e-115
Identities = 228/502 (45%), Positives = 301/502 (59%), Gaps = 48/502 (9%)
Query: 340 LGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQ----QYIR--TYGPST--NTIQQQ 391
+G LP GWEQR T GR YFVDHN RTT + DPR Q IR T P++ N
Sbjct: 542 IGPLPSGWEQRKTASGRVYFVDHNNRTTQFTDPRLSGSILQMIRRGTVPPTSAANAGTPA 601
Query: 392 PVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPR-----LPSSLDQN---VPQYKR 443
P S PS T TTT + P LP L + +P+Y+R
Sbjct: 602 PPSATPATPSAAAAVPPQATPASNATPTTLTTTTNPPHRIVPDLPQGLLEGADLLPKYRR 661
Query: 444 DFRRKVIYFRSQ-PALRILPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEE 502
D K+ R++ ++ G C + V R IFE+SY+ IM+ +D++KRLM+KF GEE
Sbjct: 662 DLVGKLRALRTELQTMQPQSGHCRLEVSRNEIFEESYRLIMKMRAKDMRKRLMVKFKGEE 721
Query: 503 GLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVV 562
GLDYGGV+RE+ LLS EM NP Y LF+YS D+YT+QINP+SG+NP+HL+YF F+
Sbjct: 722 GLDYGGVAREWLHLLSREMLNPQYGLFQYSRDDHYTLQINPDSGVNPDHLSYFHFL---- 777
Query: 563 GLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFN 622
L K + L D+EGVD +++ SL W+LE++I GI++ TF+
Sbjct: 778 ----------------------LNKPITLGDIEGVDPDLHRSLTWMLESNISGIIESTFS 815
Query: 623 VDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVP 682
V++ FG LVV +LKP G I VT+ENK+EYV+LY +R +++QF A GF EL+P
Sbjct: 816 VENNSFGALVVHELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIP 875
Query: 683 EDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRAR 742
L+ FDERELEL+IGGI+ IDV DW+ +T + + WFW+ + + +E RAR
Sbjct: 876 SHLLRPFDERELELVIGGISSIDVNDWRNNTRLKHCTNETTQVLWFWQVVESYSSEMRAR 935
Query: 743 LLQFTTGTSRIPVNGFKDLQGSD---GPRRFTIEKAGEV--QQLPKSHTCFNRVDLPPYT 797
LLQF TG+SR+P+ GF+ LQGS GPR FTI +V Q LPK+HTCFNR+DLPPY
Sbjct: 936 LLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLPPYE 995
Query: 798 DYESFKQKLTLAVEETIGFGQE 819
Y+ KLT AVEET GF E
Sbjct: 996 TYQLLCDKLTQAVEETCGFAVE 1017
Score = 90.5 bits (223), Expect = 9e-18
Identities = 55/171 (32%), Positives = 75/171 (43%), Gaps = 27/171 (15%)
Query: 268 KRPTLDQSEVQRVNTELERRQHRGRTLPDGGAQSEGSSSSNVAVHTGTGSQTPAVNXXXX 327
+R + Q E R G T GG G ++ A+ + P +
Sbjct: 441 RRSSRQQGEESSTRRRSSRGTRNGGTSGGGGGGGSGQRYASAAIAAANQAARPFL----- 495
Query: 328 XXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNT 387
+LPPG+E R T +G+ YF T +TW DPR + T
Sbjct: 496 --------------DLPPGYEMRTTQQGQVYFYHIPTGVSTWHDPRIPRDFDT------- 534
Query: 388 IQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNV 438
Q + +GPLPSGWE R T + RVYFVDHN +TT + DPRL S+ Q +
Sbjct: 535 -QHLTLDAIGPLPSGWEQRKTASGRVYFVDHNNRTTQFTDPRLSGSILQMI 584
>Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1572
Score = 405 bits (1041), Expect = e-112
Identities = 243/616 (39%), Positives = 344/616 (55%), Gaps = 53/616 (8%)
Query: 234 FEDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQH---- 289
F ++ LP GWE + D+ G+ ++VDHN+RTTT+ P L R + L RQH
Sbjct: 980 FANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQS-SRPTSALVHRQHLTRQ 1038
Query: 290 RGRTLPDGGAQSEG---------SSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXL 340
R + + G S SS+ N P L
Sbjct: 1039 RSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNIFEIL 1098
Query: 341 GELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLP 400
E P + +H+ R + Q+IRT G + ++ + L L
Sbjct: 1099 QERQPDLTR-----------NHSLR-------EKIQFIRTEG-TPGLVRLSSDADLVMLL 1139
Query: 401 SGWEMRLTNTARVYFVDHNTKTTTWDDPR-LPSSLDQNVP-----------QYKRDFRRK 448
S +E + + + + H + + PR P S QN P YKRDF K
Sbjct: 1140 SLFEEEIMSYVPPHALLHPSYCQS---PRGSPVSSPQNSPGTQRANARAPAPYKRDFEAK 1196
Query: 449 VIYFRSQPALRIL---PGQCHIRVRRKNIFEDSYQEIMRQTPEDLKK-RLMIKFDGEEGL 504
+ F + + PG+ + +RR ++ ED++ +IM + +DL++ +L + F GEEGL
Sbjct: 1197 LRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGL 1256
Query: 505 DYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGL 564
DY G SREFFFL+S E+FNP+Y LFEYSA+D YT+QI+P S H +F+F GR++GL
Sbjct: 1257 DYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGL 1316
Query: 565 GVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVD 624
+ H+ LDAFF YK +LR L D+E +D E + SL+W+ +N I ILDLTF V+
Sbjct: 1317 ALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVN 1376
Query: 625 DERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPED 684
+E FG++ +LKP G I VT++NKKEY+E +WRI V +Q ++ + GF E+V
Sbjct: 1377 EEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDAR 1436
Query: 685 LVNVFDERELELLIGGIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARL 743
LV+VFD RELEL+I G AEID+ DW+ +T+YR GY ++ VI+WFW + ++NEQR RL
Sbjct: 1437 LVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRL 1496
Query: 744 LQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFK 803
LQF TGTS IP GF L+GS+GPRRF +EK G++ LP++HTCFNR+DLPPY +
Sbjct: 1497 LQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLY 1556
Query: 804 QKLTLAVEETIGFGQE 819
+KL AVEET FG E
Sbjct: 1557 EKLLTAVEETSTFGLE 1572
Score = 76.3 bits (186), Expect = 2e-13
Identities = 63/217 (29%), Positives = 91/217 (41%), Gaps = 32/217 (14%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSE--VQRVNT-----ELERR-QHRGR 292
LPP WE R D+ GR +YVDH RTTTW+RPT + +QR N+ +L RR Q R
Sbjct: 809 LPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRR 868
Query: 293 TLP-----------DGGAQ-------SEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXX 334
T+ DG + S N+ H+ + S+ +
Sbjct: 869 TMTNERPEENTNAIDGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISP 928
Query: 335 XXXXXLGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVS 394
L P + + + R T + R Q+ R N + +
Sbjct: 929 EFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFE--RYQHNRDLVGFLNMFANKQLE 986
Query: 395 QLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLP 431
LP GWEM+ + + +FVDHN++TTT+ DPRLP
Sbjct: 987 ----LPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLP 1019
>Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1606
Score = 398 bits (1022), Expect = e-110
Identities = 239/606 (39%), Positives = 340/606 (55%), Gaps = 32/606 (5%)
Query: 234 FEDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRT 293
F D LP GWE +TD G++++VDHN+R TT+ P + R+ L RQH R
Sbjct: 1013 FADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQN-GRLPNHLTHRQHLQRL 1071
Query: 294 LP-DGGAQSEGSSSSNVAVHTGTG-SQTPAVNXXXXXXXXXXXXXXXXLGEL-PPGWEQR 350
G SE S + ++ G S A+ + L P +
Sbjct: 1072 RSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEM 1131
Query: 351 FTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNT 410
+ +H R + YIRT G + + + L L S +E + +
Sbjct: 1132 LQERQPSLARNHTLR-------EKIHYIRTEG-NHGLEKLSCDADLVILLSLFEEEIMSY 1183
Query: 411 ARVYFVDHNTKTTTWDDPRL-PSSLDQNVP-----------QYKRDFRRKVIYFRSQPAL 458
+ H + + PR P S QN P Y+RDF K+ F +
Sbjct: 1184 VPLQAAFHPGYSFS---PRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEA 1240
Query: 459 RIL---PGQCHIRVRRKNIFEDSYQEIMRQTPEDLKK-RLMIKFDGEEGLDYGGVSREFF 514
+ PG+ + +RR ++ E ++ ++M + ++L++ +L + F GEEGLDY G SREFF
Sbjct: 1241 KGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFF 1300
Query: 515 FLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDA 574
FLLS E+FNP+Y LFEYSA+D YT+QI+P S HL +F+F GR++GL + H+ LDA
Sbjct: 1301 FLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDA 1360
Query: 575 FFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVV 634
FF YK +LR L D+E +D E + SL+W+ +N+I ILDLTF V++E FG++
Sbjct: 1361 FFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTER 1420
Query: 635 DLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDEREL 694
+LK G +VT++NKKEY+E +WR+ V +Q +A + GF E+V LV+VFD REL
Sbjct: 1421 ELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDAREL 1480
Query: 695 ELLIGGIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRI 753
EL+I G AEID+ DW+ +T+YR GY + VI+WFW + ++NEQR RLLQF TGTS +
Sbjct: 1481 ELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSV 1540
Query: 754 PVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEET 813
P GF L+GS+G RRF IEK G++ LP++HTCFNR+DLPPY Y +KL AVEET
Sbjct: 1541 PYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEET 1600
Query: 814 IGFGQE 819
FG E
Sbjct: 1601 STFGLE 1606
Score = 71.6 bits (174), Expect = 4e-12
Identities = 60/226 (26%), Positives = 88/226 (38%), Gaps = 39/226 (17%)
Query: 241 LPPGWERRTDNFGRTYYVDHNTRTTTWKRPTL--------DQSEVQRVNTELERRQHRGR 292
LPP WE R D+ GR +YVDH RTTTW+RPT +Q++ R Q+ R
Sbjct: 831 LPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQR 890
Query: 293 TLPDGGAQSEGSSSSNVAVHTGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFT 352
T+ ++ + S S G G G L P Q+ T
Sbjct: 891 TIATERSEEDSGSQSCEQAPAGGGG---GGGSDSEAESSQSSLDLRREGSLSPVNSQKIT 947
Query: 353 -------------PEG----RAYFVDHNTRTTTWV----------DPRRQQYIRTYGPST 385
PE A + + T++ D R + +
Sbjct: 948 LLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLV 1007
Query: 386 NTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLP 431
N I ++L LP GWE++ + +FVDHN++ TT+ DPR+P
Sbjct: 1008 NFINMFADTRL-ELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIP 1052
>7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 388
Score = 363 bits (933), Expect = e-100
Identities = 191/385 (49%), Positives = 258/385 (66%), Gaps = 7/385 (1%)
Query: 439 PQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKK-RLMIK 497
P ++RDF K+ F + + H + ++ ED+++ IM +DL++ RL +
Sbjct: 7 PPFRRDFEAKLRSFYRKLESKGYGQGPH---KLNHLLEDAFRRIMSANKKDLQRGRLAVL 63
Query: 498 FDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKF 557
+D EEGLDYGG SREFFFLLS E+FNP+Y LFEYSA+D YT+Q++P S ++F+F
Sbjct: 64 WDTEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVQVSPLSAFVDNCHDWFRF 123
Query: 558 IGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSI-DGI 616
GRV+GL + H+ LDAFF YK +LR V L D+E +D+E + SL+WI +N I G+
Sbjct: 124 SGRVLGLALVHQYLLDAFFTRPFYKALLRLPVALSDLESLDNEFHQSLQWIRDNDIGTGV 183
Query: 617 -LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMD 675
L LTF V +E G +V +LKP G+ I + ++NKKEY+E +WR+ VQEQ ++ +
Sbjct: 184 DLGLTFCVTEELLGSVVDRELKPGGKNIIINEKNKKEYLERMIKWRLERGVQEQTESLVR 243
Query: 676 GFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITE 734
GF E++ LV+VFD RELEL+I G AEID DW+ +T+YR GY ++ +VI WFW+ I
Sbjct: 244 GFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIER 303
Query: 735 WDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLP 794
+ NEQR RLLQF TGTS IP GF L+GS GPRRF IEK G+ LP++HTCFNR+DLP
Sbjct: 304 FSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLP 363
Query: 795 PYTDYESFKQKLTLAVEETIGFGQE 819
PY E +KL LAVEET FG E
Sbjct: 364 PYPTPELLYEKLLLAVEETNTFGIE 388
>CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 875
Score = 340 bits (872), Expect = 5e-93
Identities = 172/394 (43%), Positives = 253/394 (63%), Gaps = 10/394 (2%)
Query: 429 RLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDSYQEIMRQTPE 488
+ P LD +V KR + RK + R ++V R +F DS++E+ R P
Sbjct: 485 QFPKLLDFDV---KRKYFRKELTKLEPSMPRYRRNDVSVQVSRNRVFSDSFRELFRLRPS 541
Query: 489 DLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGIN 548
+ K R I F GEEG D GG+ RE+F +++ E+FNP Y LF + D T IN S IN
Sbjct: 542 EWKNRFYIIFQGEEGQDAGGLLREWFSVITREIFNPNYALFITAPGDMVTYMINKASYIN 601
Query: 549 PEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWI 608
PEHL+YFKF+GR++ VF ++LD +F A YK +L V QD+E D + SL ++
Sbjct: 602 PEHLDYFKFVGRLIAKSVFEHKYLDCYFTRAFYKHILNLPVRYQDLESEDPAFFKSLDFL 661
Query: 609 LENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQ 667
L+N ID + LDLTF+ + E FG V DLKPNGR+IEV D NK EYV+L Q ++ ++
Sbjct: 662 LQNPIDDLALDLTFSTEVEEFGVRSVRDLKPNGRKIEVNDANKDEYVKLVCQMKMTGSIR 721
Query: 668 EQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQW 727
+Q AF+ GF E++P+DL+++F+E+ELELLI G+ +D++D +TDY+G+Q++ IQW
Sbjct: 722 KQLDAFLTGFYEIIPKDLISMFNEQELELLISGLPTVDIDDMAANTDYKGFQKTSTHIQW 781
Query: 728 FWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTI---EKAGEVQQLPKS 784
FW+ + ++ E +A+ LQF TGTS++P+ GF L+G +G ++F+I + G+ +LP +
Sbjct: 782 FWRALRSFEKEDKAKFLQFVTGTSKVPLQGFASLEGMNGVQKFSIHMDSRGGD--RLPAA 839
Query: 785 HTCFNRVDLPPYTDYESFKQKLTLAVEE-TIGFG 817
HTCFN++DLP Y YE +Q L LA+ E T GFG
Sbjct: 840 HTCFNQLDLPQYESYEKLRQSLLLAIRECTEGFG 873
>SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3227
Score = 339 bits (870), Expect = 9e-93
Identities = 167/380 (43%), Positives = 249/380 (64%), Gaps = 6/380 (1%)
Query: 444 DFRRKVIYFRSQ---PALRILPGQCHIRVRRKNIFEDSYQEIMRQTPEDLK-KRLMIKFD 499
+F K YF Q A + +I VRR ++F DSY+ + + +++K +L I F
Sbjct: 2846 EFENKRNYFNRQLHEEAAKEQYPPLNITVRRDHVFLDSYRALHFKDADEVKFSKLNIHFR 2905
Query: 500 GEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIG 559
EEG+D GGV+RE+ +L+ +MFNP Y LF D T N +S +NP+HL++FKF G
Sbjct: 2906 DEEGVDAGGVTREWLQVLARQMFNPDYALFLPVTGDATTFHPNRDSSVNPDHLSFFKFTG 2965
Query: 560 RVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDL 619
R++G ++ R LD F A+YK ML + V ++D+E +D + Y SL W+L N I I+
Sbjct: 2966 RIIGKALYDGRLLDCHFSRAVYKHMLHRSVSVKDIESLDPDYYKSLVWMLNNDITDIITE 3025
Query: 620 TFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNE 679
F V+ + FGE VVDL PNGR I VT+ NK+ YV +++ + V++Q K+ +DGF++
Sbjct: 3026 EFAVEKDVFGEKTVVDLIPNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSD 3085
Query: 680 LVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQ 739
++P L+ +F+E+ELELLI G+ EID++DWK +T+Y GY S +QWFW+ + +D E+
Sbjct: 3086 IIPSHLIQIFNEQELELLISGLPEIDIDDWKNNTEYHGYNVSSPQVQWFWRAVRSFDEEE 3145
Query: 740 RARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKA-GEVQQLPKSHTCFNRVDLPPYTD 798
RA+LLQF TGTS++P+NGFK+L+G G +RF I K+ G + +LP+SHTCFN++DLP Y
Sbjct: 3146 RAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGSLNRLPQSHTCFNQLDLPEYDT 3205
Query: 799 YESFKQKLTLAVEE-TIGFG 817
YE + L A+ E + GFG
Sbjct: 3206 YEQLRSMLLTAINEGSEGFG 3225
>At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3891
Score = 333 bits (853), Expect = 8e-91
Identities = 172/386 (44%), Positives = 245/386 (62%), Gaps = 13/386 (3%)
Query: 444 DFRRKVIYFRSQPALRI---LPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDG 500
DF K YFRS+ + + G I VRR + EDSY ++ ++P+DLK RL ++F G
Sbjct: 3505 DFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDSYNQLRMRSPQDLKGRLNVQFQG 3564
Query: 501 EEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGR 560
EEG+D GG++RE++ LLS +F+ LF +D T Q NPNS EHL+YFKF+GR
Sbjct: 3565 EEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDA-TFQPNPNSVYQTEHLSYFKFVGR 3623
Query: 561 VVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLT 620
+V +F + LD +F + YK +L KV D+E VD + Y +LKW+LEN + ILDLT
Sbjct: 3624 MVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLT 3683
Query: 621 FNVDDERFG-------ELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAF 673
F++D + E+ +LKP GR I VT+E K EYV+L + + ++ Q AF
Sbjct: 3684 FSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQINAF 3743
Query: 674 MDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCIT 733
++GFNEL+P +LV++F+++ELELLI G+ EID +D K +T+Y Y VI WFW+ +
Sbjct: 3744 LEGFNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTAGSPVIHWFWEVVK 3803
Query: 734 EWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKA-GEVQQLPKSHTCFNRVD 792
+ E AR LQF TGTS++P+ GFK LQG GP+R I KA G ++LP +HTCFN++D
Sbjct: 3804 AFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLD 3863
Query: 793 LPPYTDYESFKQKLTLAVEE-TIGFG 817
LP Y E +++L LA+ E + GFG
Sbjct: 3864 LPEYQSKEQLQERLLLAIHEASEGFG 3889
>At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3658
Score = 330 bits (847), Expect = 4e-90
Identities = 171/386 (44%), Positives = 243/386 (62%), Gaps = 13/386 (3%)
Query: 444 DFRRKVIYFRSQPALRI---LPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDG 500
DF K YFRS+ + + G I VRR + EDSY ++ ++P+DLK RL ++F G
Sbjct: 3272 DFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDSYNQLRMRSPQDLKGRLNVQFQG 3331
Query: 501 EEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGR 560
EEG+D GG++RE++ LLS +F+ LF +D T Q NPNS EHL+YFKF+GR
Sbjct: 3332 EEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNDA-TFQPNPNSVYQTEHLSYFKFVGR 3390
Query: 561 VVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLT 620
+V +F + LD +F + YK +L KV D+E VD + Y +LKW+LEN + ILDLT
Sbjct: 3391 MVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLT 3450
Query: 621 FNVDDERFG-------ELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAF 673
F++D + E+ +LKP GR I VT+E K EYV+L + ++ Q AF
Sbjct: 3451 FSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVADHILTSAIRPQINAF 3510
Query: 674 MDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCIT 733
++G NEL+P +LV++F+++ELELLI G+ EID +D K +T+Y Y VI+WFW+ +
Sbjct: 3511 LEGLNELIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTVGSPVIRWFWEVVK 3570
Query: 734 EWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKA-GEVQQLPKSHTCFNRVD 792
+ E AR LQF TGTS++P+ GFK LQG GP+R I KA G ++LP +HTCFN++D
Sbjct: 3571 AFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGSPERLPSAHTCFNQLD 3630
Query: 793 LPPYTDYESFKQKLTLAVEE-TIGFG 817
LP Y E +++L LA+ E GFG
Sbjct: 3631 LPEYQSKEQVQERLLLAIHEANEGFG 3656
>YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3268
Score = 325 bits (833), Expect = 2e-88
Identities = 160/354 (45%), Positives = 241/354 (67%), Gaps = 3/354 (0%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKK-RLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPF 525
I VRR+ +F DSY+ + +T +++K +L I F GE G+D GGV+RE++ +LS +MFNP
Sbjct: 2913 ITVRREQVFLDSYRALFFKTNDEIKNSKLEITFKGESGVDAGGVTREWYQVLSRQMFNPD 2972
Query: 526 YCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMML 585
Y LF D T N SGINPEHL++FKFIG ++G + + FLD F +YK +L
Sbjct: 2973 YALFLPVPSDKTTFHPNRTSGINPEHLSFFKFIGMIIGKAIRDQCFLDCHFSREVYKNIL 3032
Query: 586 RKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEV 645
+ V L+DME +D + Y SL WILEN I I++ TF+V+ + +GE V++L G++I V
Sbjct: 3033 GRPVSLKDMESLDPDYYKSLVWILENDITDIIEETFSVETDDYGEHKVINLIEGGKDIIV 3092
Query: 646 TDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEID 705
T+ NK++YV+ ++++ V+EQ F+ GF L+ +DL+ +FDE+ELELLI G+ +ID
Sbjct: 3093 TEANKQDYVKKVVEYKLQTSVKEQMDNFLVGFYALISKDLITIFDEQELELLISGLPDID 3152
Query: 706 VEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSD 765
V+DWK +T Y Y + + + +FW+ + +D E+RA+LLQF TGTS++P+NGFK+L G +
Sbjct: 3153 VDDWKNNTTYVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSGVN 3212
Query: 766 GPRRFTIEK-AGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEE-TIGFG 817
G +F+I + G ++LP SHTCFN+++LPPY YE+ + L LA+ E GFG
Sbjct: 3213 GVCKFSIHRDFGSSERLPSSHTCFNQLNLPPYESYETLRGSLLLAINEGHEGFG 3266
>7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 5002
Score = 317 bits (812), Expect = 5e-86
Identities = 152/354 (42%), Positives = 230/354 (64%), Gaps = 3/354 (0%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+ VRR +FEDS++ + R PE+ K R I F+ EEG D GG+ RE++ ++S E+FNP Y
Sbjct: 4647 VSVRRVTVFEDSFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIFNPMY 4706
Query: 527 CLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLR 586
LF S D T INP+S NP HL+YFKF+GRV+ V + L+ +F + YK +L
Sbjct: 4707 ALFCVSPGDRVTYMINPSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKHILG 4766
Query: 587 KKVVLQDMEGVDSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEV 645
K+V DME D E Y L ++++N I + +LTF+ + + FG + DLKPNGR+ V
Sbjct: 4767 KQVKHTDMESQDYEFYKGLDYLMKNDISTLGYELTFSTEVQEFGVTQIRDLKPNGRDTAV 4826
Query: 646 TDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEID 705
T+ENK EYV+L Q +++ +++Q AF++GF +++P+ L+++F+E+ELELLI G+ +ID
Sbjct: 4827 TEENKFEYVQLVCQLKMSGSIRQQLDAFLEGFYDIIPKHLISIFNEQELELLISGLPDID 4886
Query: 706 VEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSD 765
+ED K +T+Y Y IQWFW+ + +D RA+ LQF TGTS++P+ GF L+G +
Sbjct: 4887 IEDLKANTEYHKYTSKSAQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFGSLEGMN 4946
Query: 766 GPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEE-TIGFG 817
G ++F I + +LP +HTCFN++DLP Y Y+ + L A+ E + GFG
Sbjct: 4947 GIQKFQIHRDDRSTDRLPCAHTCFNQLDLPMYKSYDKLRSCLLKAIHECSEGFG 5000
>ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 2410
Score = 303 bits (777), Expect = 5e-82
Identities = 149/354 (42%), Positives = 225/354 (63%), Gaps = 3/354 (0%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLK-KRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPF 525
+ V R ++ SY ++M ++PE+ + +RL IK GEEGLDYGG++RE+ LL+ ++ +P
Sbjct: 2055 VYVDRSDVLRSSYFQVMAKSPEEFRTRRLEIKLTGEEGLDYGGLTREWLVLLAKDLLDPN 2114
Query: 526 YCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMML 585
+ LFE++ D T+ NS +NPEHL+YFKF+GR++ + F++ +Y+ +L
Sbjct: 2115 FALFEFATEDKTTVVPCKNSYVNPEHLSYFKFVGRIIAKAIMDGNFINLHLSKFIYQYIL 2174
Query: 586 RKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEV 645
K LQD+E D E + SL WI +N +D L +TF+ DD FG V+L G + V
Sbjct: 2175 GKSCDLQDLESADPEFHKSLVWIRDNPVDKSLGITFSFDDVSFGVHRTVELVEGGAHVFV 2234
Query: 646 TDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEID 705
D NK EYV+L TQ+R+ + ++ Q A G E++ + +FDE ELELLI GI +ID
Sbjct: 2235 DDSNKAEYVKLATQYRLFNGIELQLSALKSGLFEILGSKALEMFDESELELLICGIPDID 2294
Query: 706 VEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSD 765
V+DWK +T Y GY E+ + + WFW+ + D+ RA+LLQF TGTS +P GF LQG++
Sbjct: 2295 VDDWKNNTLYYGYAENSKTVIWFWRAVKSLDSVSRAKLLQFVTGTSTLPFEGFSHLQGNN 2354
Query: 766 GPRRFTIEKAGE-VQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEE-TIGFG 817
++F+I K + + LP +HTCFN++ LP Y+ YE+ + LTLA+ E + GFG
Sbjct: 2355 EVQKFSIHKVSDRIDSLPTAHTCFNQLVLPEYSSYENLLKYLTLAINECSTGFG 2408
>Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 562
Score = 286 bits (731), Expect = 1e-76
Identities = 150/345 (43%), Positives = 214/345 (61%), Gaps = 5/345 (1%)
Query: 469 VRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCL 528
V R +IF S + + + LK+ + ++F GEEG+ G V RE+F +LS+E+ NP Y L
Sbjct: 210 VHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQG-VVREWFDILSNEIVNPDYAL 268
Query: 529 FEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKK 588
F SA D T Q N NS +NP+HLNYF+F G+++GL + HR+ ++ +F + YK +L
Sbjct: 269 FTQSA-DGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIP 327
Query: 589 VVLQDMEGVDSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVVDLKPNGREIEVTD 647
V QD+ +D E +L+WIL+N I + L+LTF+V+ + FG + V LKP G I VT
Sbjct: 328 VNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQ 387
Query: 648 ENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVE 707
NK EYV+L T+ R+ +Q Q AF+ GF+ +P L+ +FDE ELELL+ G+ EIDV
Sbjct: 388 NNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVS 447
Query: 708 DWKKHTDY-RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDG 766
DW K+T+Y GY+ D VIQWFW+ + + E+R LLQF TG+SR+P GF ++ G G
Sbjct: 448 DWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSG 507
Query: 767 PRRFTIEKAGEVQQ-LPKSHTCFNRVDLPPYTDYESFKQKLTLAV 810
+ FTI LP S TC N + LP Y E K +L +A+
Sbjct: 508 LQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVAL 552
>Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 308
Score = 285 bits (730), Expect = 2e-76
Identities = 138/305 (45%), Positives = 197/305 (64%), Gaps = 3/305 (0%)
Query: 516 LLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAF 575
++S EMFNP Y LF S D T INP+S NP HL+YFKF+GR+V V+ R L+ +
Sbjct: 2 IISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECY 61
Query: 576 FVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGI-LDLTFNVDDERFGELVVV 634
F + YK +L K V DME D Y L ++LEN + + DLTF+ + + FG V
Sbjct: 62 FTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVR 121
Query: 635 DLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDEREL 694
DLKPNG I VT+ENKKEYV L Q R+ +++Q AF++GF E++P+ L+++F E+EL
Sbjct: 122 DLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL 181
Query: 695 ELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIP 754
ELLI G+ ID++D K +T+Y YQ + IQWFW+ + +D RA+ LQF TGTS++P
Sbjct: 182 ELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 241
Query: 755 VNGFKDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEE- 812
+ GF L+G +G ++F I + +LP +HTCFN++DLP Y +E + L LA++E
Sbjct: 242 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC 301
Query: 813 TIGFG 817
+ GFG
Sbjct: 302 SEGFG 306
>CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 889
Score = 245 bits (626), Expect = 2e-64
Identities = 151/519 (29%), Positives = 256/519 (49%), Gaps = 45/519 (8%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQY-IRTYGPSTNTIQQQPVSQLGPLPS 401
LP GWE T R F++H + T++ DPR +++ +T + + + G +
Sbjct: 374 LPSGWEC-ITMNNRTVFLNHANKETSFYDPRIRRFETKTSRRGRSVPSRSSTAHKGKIDH 432
Query: 402 GWEMRLTNTARV------YFVDHNTK----------------TTTWDDPRLPSSLDQNVP 439
+ + ++ + +K D S LD N
Sbjct: 433 ALISKCEDLRKIAQDNFPQIAERISKKLMLIERFGGLAVASLANDLDITLALSMLDSNTE 492
Query: 440 QYKRDFRRKVIYFRSQPALRILPGQCHI--RVRRKNIFEDSYQEIMRQTPEDLKK-RLMI 496
+ + +++ ++ G + +V R + +D+++ I+ P LKK RL I
Sbjct: 493 KLAGEGDNIKMFYEDMKKEKLGKGPSRLCWKVSRDRLLDDAFRIILNVDPFVLKKSRLHI 552
Query: 497 KFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFK 556
+F+GE LDYGG+SREFF LLS E+F+P FEY +D Y +Q+ P + +
Sbjct: 553 RFEGELALDYGGLSREFFILLSRELFHPKNGYFEYEGND-YHLQLRPRGCETEKEKKWLI 611
Query: 557 FIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGI 616
GRV+ L V HR ++D FF YK + ++ V L D + D+E Y S+ W+LEN +
Sbjct: 612 LCGRVLALAVIHRCYIDVFFTNVFYKSLQKRPVTLMDFKESDAEFYKSMNWLLENDVVD- 670
Query: 617 LDLTF--------NVDDERFGELVVV-------DLKPNGREIEVTDENKKEYVELYTQWR 661
L+++F V D +V V +L P G VT+ NK E+++L Q +
Sbjct: 671 LEMSFVYSSMVNGKVSDLTLSSIVSVALQLAEQELVPGGESQMVTEANKAEFIDLMCQKK 730
Query: 662 IADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRG-YQE 720
V++ + + FN+++ ++L+N + +L+ ++ G E+D+ DW+ +T Y+G Y +
Sbjct: 731 AIRGVEKPLEILLTSFNQILNDNLLNSLESSDLKRILSGSLELDLNDWRTNTIYKGGYSD 790
Query: 721 SDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQ 780
V++WFW+ I N++R LL F TG+S +P GF L+G++ +F IEK G+
Sbjct: 791 CHIVVEWFWEVIETMTNQERFDLLLFVTGSSSVPFEGFSALRGNEEISKFCIEKWGDATS 850
Query: 781 LPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
P++HTCFNR+ LP Y + K KL A+ + + E
Sbjct: 851 FPRAHTCFNRLQLPSYNTKQQLKSKLQQAIVNGMSYSIE 889
>Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase
Length = 875
Score = 217 bits (552), Expect = 7e-56
Identities = 132/360 (36%), Positives = 206/360 (56%), Gaps = 20/360 (5%)
Query: 467 IRVRRKNIFEDSY---QEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFN 523
++VRR +I +D+ + I + P DLKK+L ++F+GE+G+D GGVS+EFF L+ E+FN
Sbjct: 525 LKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFN 584
Query: 524 PFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKM 583
P +F Y NP+S E F IG V+GL +++ LD F +Y+
Sbjct: 585 PDIGMFTYD-ESTKLFWFNPSSF---ETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRK 640
Query: 584 MLRKKVVLQDMEGVDSEVYNSLKWIL--ENSIDGILDLTFNVDD-ERFGELVVVDLKPNG 640
++ KK +D+ +Y SLK +L E +++ + +TF + + FG ++ DLK NG
Sbjct: 641 LMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENG 700
Query: 641 REIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPED-LVNVFDERELELLIG 699
+I +T+EN+KE+V LY+ + + V++QFKAF GF+ + E L +F E+ELLI
Sbjct: 701 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 760
Query: 700 GIAEIDVEDWKKHTDY-RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGF 758
G +D + ++ T+Y GY +I+ FW+ + + +EQ+ LQFTTGT R PV G
Sbjct: 761 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 820
Query: 759 KDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFG 817
G + I K G + ++LP SHTCFN + LP Y+ E K++L A+ GFG
Sbjct: 821 -------GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFG 873
>Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase
Length = 872
Score = 217 bits (552), Expect = 7e-56
Identities = 132/360 (36%), Positives = 206/360 (56%), Gaps = 20/360 (5%)
Query: 467 IRVRRKNIFEDSY---QEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFN 523
++VRR +I +D+ + I + P DLKK+L ++F+GE+G+D GGVS+EFF L+ E+FN
Sbjct: 522 LKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFN 581
Query: 524 PFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKM 583
P +F Y NP+S E F IG V+GL +++ LD F +Y+
Sbjct: 582 PDIGMFTYD-ESTKLFWFNPSSF---ETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRK 637
Query: 584 MLRKKVVLQDMEGVDSEVYNSLKWIL--ENSIDGILDLTFNVDD-ERFGELVVVDLKPNG 640
++ KK +D+ +Y SLK +L E +++ + +TF + + FG ++ DLK NG
Sbjct: 638 LMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENG 697
Query: 641 REIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPED-LVNVFDERELELLIG 699
+I +T+EN+KE+V LY+ + + V++QFKAF GF+ + E L +F E+ELLI
Sbjct: 698 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 757
Query: 700 GIAEIDVEDWKKHTDY-RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGF 758
G +D + ++ T+Y GY +I+ FW+ + + +EQ+ LQFTTGT R PV G
Sbjct: 758 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 817
Query: 759 KDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFG 817
G + I K G + ++LP SHTCFN + LP Y+ E K++L A+ GFG
Sbjct: 818 -------GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFG 870
>Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase
Length = 852
Score = 217 bits (552), Expect = 7e-56
Identities = 132/360 (36%), Positives = 206/360 (56%), Gaps = 20/360 (5%)
Query: 467 IRVRRKNIFEDSY---QEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFN 523
++VRR +I +D+ + I + P DLKK+L ++F+GE+G+D GGVS+EFF L+ E+FN
Sbjct: 502 LKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFN 561
Query: 524 PFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKM 583
P +F Y NP+S E F IG V+GL +++ LD F +Y+
Sbjct: 562 PDIGMFTYD-ESTKLFWFNPSSF---ETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRK 617
Query: 584 MLRKKVVLQDMEGVDSEVYNSLKWIL--ENSIDGILDLTFNVDD-ERFGELVVVDLKPNG 640
++ KK +D+ +Y SLK +L E +++ + +TF + + FG ++ DLK NG
Sbjct: 618 LMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENG 677
Query: 641 REIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPED-LVNVFDERELELLIG 699
+I +T+EN+KE+V LY+ + + V++QFKAF GF+ + E L +F E+ELLI
Sbjct: 678 DKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLIC 737
Query: 700 GIAEIDVEDWKKHTDY-RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGF 758
G +D + ++ T+Y GY +I+ FW+ + + +EQ+ LQFTTGT R PV G
Sbjct: 738 GSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGL 797
Query: 759 KDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFG 817
G + I K G + ++LP SHTCFN + LP Y+ E K++L A+ GFG
Sbjct: 798 -------GKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFG 850
>7292061 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1057
Score = 206 bits (524), Expect = 1e-52
Identities = 123/355 (34%), Positives = 194/355 (54%), Gaps = 17/355 (4%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+ V R+N+ +DS +E+ + DLKK L IKF GEE D GGV +EFF LL ++ +P Y
Sbjct: 712 LNVTRENLVQDSLRELQHYSQSDLKKPLKIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKY 771
Query: 527 CLF-EYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMML 585
+F EY ++ + + E N + IG + GL +++ ++ F AL+K +L
Sbjct: 772 GMFKEYEQS-----RLLWFADLTFETENMYFLIGVLCGLAIYNFTIINLPFPLALFKKLL 826
Query: 586 RKKVVLQDMEGVDSEVYNSLKWILENSIDG---ILDLTFNVDDERFGELVVVDLKPNGRE 642
K V L D+ + NS++ +L+ D + DLTF + + FGE LKPNG E
Sbjct: 827 GKPVDLSDLRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKCLKPNGNE 886
Query: 643 IEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIA 702
I VT EN++E+V+LY + V+ + AF GF ++ ++++F EL ++ G
Sbjct: 887 IAVTLENRQEFVDLYVDFVFNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVGNE 946
Query: 703 EIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDL 761
+ D + + + +YR GY D+ I+WFW+ I + ++ L F TG+ RIP+ G K L
Sbjct: 947 DYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIPIQGMKAL 1006
Query: 762 QGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
+ TI+ + + LP +HTCFN +DLP Y E K KL A+++T GF
Sbjct: 1007 -------KLTIQPTPDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAIQQTQGF 1054
>7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 971
Score = 201 bits (510), Expect = 5e-51
Identities = 124/371 (33%), Positives = 206/371 (55%), Gaps = 30/371 (8%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNP-- 524
++V+R+ I E S + + + D + F GE+G+D+GG+ RE+F L+ +F+
Sbjct: 609 LKVQREKILESSMKAVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDARG 668
Query: 525 -FYCLFEYSAHDNYTIQINPNSGINPEHLN--YFKFIGRVVG-------LGVFHRRFLDA 574
+C F HD + ++PN P HL +F+F G++VG LG +R+ + A
Sbjct: 669 GLFCTF----HDKHQALVHPNP-TRPAHLKLKHFEFAGKMVGKCLFESALGGTYRQLVRA 723
Query: 575 FFVGALYKMMLRKKVVLQDMEGVDSEVYNS-LKWILENSIDGI--LDLTF--NVDDERFG 629
F + ++ +V + E D ++Y S +K+IL+ +D L+L F + D G
Sbjct: 724 RFSRSFLAQLIGLRVHYKYFEQDDPDLYLSKIKYILDTDLDATDTLELYFVEEMYDSSSG 783
Query: 630 ELV-VVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNV 688
+L ++L PNG + VT+ K +Y++ Q R+ + V+++ +F+ G N ++P++L+++
Sbjct: 784 QLSKTIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLSI 843
Query: 689 FDERELELLIGGIAEIDVEDWKKHTDYRGYQ-ESDEVIQWFWKCITEWDNEQRARLLQFT 747
FDE ELELL+ G E + D+K H G E V+ WFW ++ + + ARLLQFT
Sbjct: 844 FDENELELLMCGTGEYSISDFKAHHIANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQFT 903
Query: 748 TGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLT 807
TG S++P GF++L +F I A LP +HTCFN++ LP Y YE F++ L
Sbjct: 904 TGCSQLPPGGFQELN-----PQFQITAAPTFGNLPTAHTCFNQLCLPDYESYEQFEKSLL 958
Query: 808 LAVEE-TIGFG 817
LA+ E + GFG
Sbjct: 959 LAISEGSEGFG 969
>At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 873
Score = 198 bits (503), Expect = 3e-50
Identities = 118/358 (32%), Positives = 190/358 (52%), Gaps = 18/358 (5%)
Query: 469 VRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCL 528
+ R N+ +S++ I+ +PE L L ++F EE GV RE+F+L+ E+FNP L
Sbjct: 515 IDRSNLLSESFEYIVGASPEALHGGLFMEFKNEEATG-PGVLREWFYLVCQEIFNPKNTL 573
Query: 529 FEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKK 588
F SA D NP S ++P H ++F+F GRV+ L + H+ + F + + K
Sbjct: 574 FLRSADDFRRFSPNPASKVDPLHPDFFEFTGRVIALALMHKVQVGVLFDRVFFLQLAGLK 633
Query: 589 VVLQDMEGVDSEVYNSLKWILENSIDGI-----LDLTFNVDDERFGELVVVDLKPNGREI 643
+ L+D++ D +YNS K ILE + L LTF ++ E G+ ++L P+G+
Sbjct: 634 ISLEDIKDTDRIMYNSCKQILEMDPEFFDSNAGLGLTFVLETEELGKRDTIELCPDGKLK 693
Query: 644 EVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLV--NVFDERELE----LL 697
V +N+K+YV+L + R A + EQ K F GF +++ + + F LE +L
Sbjct: 694 AVNSKNRKQYVDLLIERRFATPILEQVKQFSRGFTDMLSHSVPPRSFFKRLYLEDLDGML 753
Query: 698 IGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNG 757
GG I ++DWK HT+Y G++E+D I WFWK + + E++ +L F T +PV G
Sbjct: 754 RGGENPISIDDWKAHTEYNGFKETDRQIDWFWKILKKMTEEEQRSILFFWTSNKFVPVEG 813
Query: 758 FKDLQGSDGPRRFTIEKAGEV-QQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETI 814
F+ L + I + E +LP SHTCF R+ +P Y +Q+L L ++ +
Sbjct: 814 FRGLSS-----KLYIYRLYEANDRLPLSHTCFYRLCIPRYPTITLMEQRLRLIAQDHV 866
>7294742 [O] KOG0941 E3 ubiquitin protein ligase
Length = 973
Score = 190 bits (482), Expect = 9e-48
Identities = 117/362 (32%), Positives = 196/362 (53%), Gaps = 23/362 (6%)
Query: 467 IRVRRKNIFEDSY---QEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFN 523
+ VRR + D+ + + P+DLKK+L+++F GE+G+D GGVS+EFF L+ E+FN
Sbjct: 622 LTVRRDQLINDALIGLEMVAMSNPKDLKKQLVVEFVGEQGIDEGGVSKEFFQLIVEEIFN 681
Query: 524 PFYCLF-EYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYK 582
P + +F + +N P E+ F IG ++GL +++ L F +Y+
Sbjct: 682 PAFGMFIQQEETNNMWFNATPF-----ENGAQFTLIGIIIGLAIYNNVTLAVNFPMVVYR 736
Query: 583 MMLRKKVVLQDMEGVDSEVYNSLKWILE---NSIDGILDLTFNVD-DERFGELVVVDLKP 638
++ D+ +Y SLK +L+ ++ + + TF + + FG++V +L P
Sbjct: 737 KLIGYCGTFADLSDWSPALYKSLKSMLDYQGQDMEEVFEQTFKISYSDVFGDVVQHELVP 796
Query: 639 NGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPED-LVNVFDERELELL 697
NG+++ V NK+ +V LY+ + + +++QF AF GF + E L +F E+E+L
Sbjct: 797 NGQDVLVGQHNKELFVNLYSDFLLNTNIEQQFNAFRKGFEMVTDESPLKLLFRPEEIEML 856
Query: 698 IGGIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVN 756
+ G E D + + T Y GY E + IQ FW + +E + +LL+FTTG++R+PV
Sbjct: 857 VCGSREFDFVELENSTVYEGGYTEKSQYIQDFWSIVHAMPSEDKHKLLEFTTGSARVPVG 916
Query: 757 GFKDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIG 815
G K L R I + G + +LP SHTCFN + LP Y+ E +++L A+ + G
Sbjct: 917 GLKCL-------RLLITRHGPDSDRLPTSHTCFNVLLLPEYSSREKLEERLMKAINYSKG 969
Query: 816 FG 817
FG
Sbjct: 970 FG 971
>Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 823
Score = 189 bits (481), Expect = 1e-47
Identities = 132/391 (33%), Positives = 206/391 (51%), Gaps = 26/391 (6%)
Query: 445 FRRKVIYFRS---QPALRILPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGE 501
F+ KV +F+ Q ++ + ++V R + E S + + D K + F E
Sbjct: 439 FQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDE 498
Query: 502 EGLDYGGVSREFFFLLSHEMFNPFYCLF-EYSAHDNYTIQINPNSGINPEHLNY--FKFI 558
E LD+GG RE+F L+ +F+ LF +S ++ + NPN P HL ++F
Sbjct: 499 EALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPN---RPAHLRLKMYEFA 555
Query: 559 GRVVG-------LGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILEN 611
GR+VG LG +++ + A F + ++ ++ + E D E Y S + N
Sbjct: 556 GRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILN 615
Query: 612 SIDGILDLTFNVDD-ERFGEL-VVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQ 669
+ ++L F + + G+L VV+L G + VT+ NK Y+ L Q+R+A +V+E+
Sbjct: 616 NDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEE 675
Query: 670 FKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRG--YQESDEVIQW 727
+ F+ G NELVPE+L+ +FDE ELELL+ G +I V D+K H G + ++V++W
Sbjct: 676 VEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRW 735
Query: 728 FWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTC 787
FW ++ E+ ARLLQFTTG+S++P GF L S F I A LP +HTC
Sbjct: 736 FWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPS-----FQIIAAPTHSTLPTAHTC 790
Query: 788 FNRVDLPPYTDYESFKQKLTLAVEETI-GFG 817
FN++ LP Y YE + L LA+ E GFG
Sbjct: 791 FNQLCLPTYDSYEEVHRMLQLAISEGCEGFG 821
>At3g17205 [O] KOG0942 E3 ubiquitin protein ligase
Length = 873
Score = 186 bits (472), Expect = 1e-46
Identities = 111/364 (30%), Positives = 198/364 (53%), Gaps = 22/364 (6%)
Query: 468 RVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGE-----EGLDYGGVSREFFFLLSHEMF 522
R+RR +I ED+Y ++ + +DL+ + + F E G+D GG+ ++F ++ F
Sbjct: 514 RIRRDHILEDAYNQMSALSEDDLRSSIRVTFVNELGVEEAGIDGGGIFKDFMEKITRAAF 573
Query: 523 NPFYCLFEYSAHDNYTIQINPNSG-INPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALY 581
+ Y LF+ +A ++ + NP SG I+ +HL +F F+G ++ +F +D F
Sbjct: 574 DVQYGLFKETA--DHMLYPNPGSGMIHEQHLQFFHFLGSLLAKAMFEGILVDIPFATFFL 631
Query: 582 KMMLRKKVVLQDMEGVDSEVYNSLKWILENSID-GILDLTFNVDDERFGELVVVDLKPNG 640
+ +K L D+ +D E+Y L ++ D L+L F + + +GE +L P G
Sbjct: 632 SKLKQKYNYLNDLPSLDPELYRHLIFLKRYKGDISDLELYFVILNNEYGERTEEELLPGG 691
Query: 641 REIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLI-G 699
+++ VT+EN ++ L + R+ ++++Q F+ GF +L+P++ +++F+E EL++LI G
Sbjct: 692 QDMRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIPKEWIDMFNEHELQVLISG 751
Query: 700 GIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGF 758
+ +D++D + +T+Y GY VI FW+ + + E + + L+F TG SR P+ GF
Sbjct: 752 SVDSLDIDDLRNNTNYAGGYHAGHYVIDMFWEVMKSFSTENQKKFLKFVTGCSRGPLLGF 811
Query: 759 KDLQGSDGPRRFTIEKAG------EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEE 812
K L+ + F I++A V +LP S TC N + LPPY E + KL A+
Sbjct: 812 KYLEPA-----FCIQRAAGSASNESVDRLPTSATCMNLLKLPPYQSKELLETKLMYAISA 866
Query: 813 TIGF 816
GF
Sbjct: 867 EAGF 870
>7291760 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1122
Score = 181 bits (460), Expect = 3e-45
Identities = 113/361 (31%), Positives = 194/361 (53%), Gaps = 18/361 (4%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDG-----EEGLDYGGVSREFFFLLSHEM 521
I VRR +++ED+Y ++ DL+ + I+F E G+D GGV REF L
Sbjct: 766 ITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTA 825
Query: 522 FNPFYCLFEYSAHDNYTIQINPN-SGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGAL 580
F+P F + + + NPN + + ++ ++ FIGR++G ++ ++
Sbjct: 826 FDPNRGFFMVTTDNK--LYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFF 883
Query: 581 YKMMLRK--KVVLQDMEGVDSEVYNSLKWILENSID-GILDLTFNVDDERFGELVVVDLK 637
+ K V + + +D E+Y +L ++ + S D L+L F V G+ +V+LK
Sbjct: 884 LTKLAGKYSDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELK 943
Query: 638 PNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELL 697
P G+ I VT+ N+ EY++L +++ +++ AF G + ++P + + +F +EL++L
Sbjct: 944 PQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQIL 1003
Query: 698 IGGI-AEIDVEDWKKHTDYRG-YQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPV 755
I G ID+ED KKH +Y G + I FW+ + +D+ QR +LL+F T SR P+
Sbjct: 1004 ISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPL 1063
Query: 756 NGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIG 815
GFKDL D P F I+ G++++LP + TC N + LPP+ E ++KL A++ G
Sbjct: 1064 LGFKDL---DPP--FFIQNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAG 1118
Query: 816 F 816
F
Sbjct: 1119 F 1119
>Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1050
Score = 178 bits (451), Expect = 3e-44
Identities = 111/355 (31%), Positives = 185/355 (51%), Gaps = 16/355 (4%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+ VRR N+ D+ +E+ + DLKK L + FDGEE +D GGV++EFF LL E+ NP Y
Sbjct: 704 LHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIY 763
Query: 527 CLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLR 586
+F Y D+ + + + EH N+F IG GL +++ +D F ALYK +L
Sbjct: 764 GMFTY-YQDSNLLWFSDTCFV--EH-NWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLN 819
Query: 587 KKVVLQDMEGVDSEVYNSLKWILE---NSIDGILDLTFNVDDERFGELVVVDLKPNGREI 643
K L+D++ + SL+ +L+ ++ L F + E +G + L P G +
Sbjct: 820 VKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNV 879
Query: 644 EVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAE 703
V +N++E+V+ Y + V E + AF GF ++ ++ +F EL ++ G +
Sbjct: 880 TVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSN 939
Query: 704 IDVEDWKKHTDYRG-YQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQ 762
+ E+ ++ Y+G Y + ++ FW+ E+ E++ + L F TG+ RIP+ G LQ
Sbjct: 940 YNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQ 999
Query: 763 GSDGPRRFTIEK-AGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
I+ A + LP +HTC+N +DLP Y+ E +LT A++ GF
Sbjct: 1000 -------IVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGF 1047
>Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1068
Score = 173 bits (439), Expect = 8e-43
Identities = 120/389 (30%), Positives = 191/389 (48%), Gaps = 35/389 (8%)
Query: 462 PGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDG-----EEGLDYGGVSREFFFL 516
P HI +RR + ED Y+++ + + +K + +KF E G+D GV +EF
Sbjct: 678 PHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEE 737
Query: 517 LSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFF 576
+ +F+P LF+ ++ D + +P S I+ +L F+F+G+++G V+ +D F
Sbjct: 738 IIKRVFDPALNLFKTTSGDE-RLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPF 796
Query: 577 VGALYKMMLRKK-----VVLQDMEGVDSEVYNSLKWILENSIDGI-LDLTFNVDDERFGE 630
+L + ++ +DSE Y +L I D L LT + D++ G+
Sbjct: 797 ASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYDEDVMGQ 856
Query: 631 LVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFD 690
LV +L P G+ I VT+ENK Y+ L +R+ +++ Q A + GF ++ + + +F
Sbjct: 857 LVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFS 916
Query: 691 ERELELLIGG-IAEIDVEDWKKHT-DYRGYQESDEVIQWFWKCI-TEWDNEQRARLLQFT 747
EL+ LI G AEID+ED KKHT Y G+ S VI W W + +++ ++RA L+F
Sbjct: 917 TPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFV 976
Query: 748 TGTSRIPVNGFK--------------------DLQGSDGPRRFTIEKAGEVQQLPKSHTC 787
T SR P+ GF D GS FTI K +LP S TC
Sbjct: 977 TSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTC 1036
Query: 788 FNRVDLPPYTDYESFKQKLTLAVEETIGF 816
FN + LP Y+ ++KL A+ GF
Sbjct: 1037 FNLLKLPNYSKKSVLREKLRYAISMNTGF 1065
>SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase
Length = 1029
Score = 173 bits (438), Expect = 1e-42
Identities = 113/366 (30%), Positives = 189/366 (50%), Gaps = 25/366 (6%)
Query: 466 HIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGE-----EGLDYGGVSREFFFLLSHE 520
H +RR IF+D + + + LK + I F E EG+D GG+++EF +
Sbjct: 673 HAVIRRNRIFDDGF-DAFYNFGKLLKGPIRITFVDEHGVVEEGIDGGGLTKEFLTSICKT 731
Query: 521 MFNPFYCLF-EYSAHDNYTIQINPNSGI---NPEHLNYFKFIGRVVGLGVFHRRFLDAFF 576
+F+ Y LF E AH Y PN+ + E L ++F+G ++G ++ +DA F
Sbjct: 732 VFDINYGLFSETKAHLLY-----PNTHAYAQDVERLRCYEFLGMLIGKCIYEGIQIDAAF 786
Query: 577 VGALYKMMLRKKVVLQDMEGVDSEVYNSLKWI--LENSIDGILDLTFNVDDERFGELVVV 634
L D+ +D +Y L ++ + ++ + L F V E FG V+
Sbjct: 787 ASFFVAKWLGHPSYFDDLTSLDPNLYEGLVFLKNYDGDVENDMALNFTVVHEEFGVRNVI 846
Query: 635 DLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDEREL 694
DL PNG I VT+EN+ +Y+ L + + + R+ Q +AF +GF +++ + +F E E+
Sbjct: 847 DLIPNGSNISVTNENRLQYIHLVSNYYLNARLSRQCRAFTNGFTQIIDPHWLAMFHESEI 906
Query: 695 ELLIGG-IAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSR 752
++L+GG ID++D ++HT Y GY+ + I FW+ + E++ E + ++F T +R
Sbjct: 907 QILVGGDPVPIDIDDLRRHTVYAGGYEPNSPTIVLFWEVLREFEEEDKRSFVKFVTSVAR 966
Query: 753 IPVNGFKDLQGSDGPRRFTIEKAGEVQ-QLPKSHTCFNRVDLPPYTDYESFKQKLTLAVE 811
P+ GFK L S F I GE + +LP + TC N + LP Y+ ++ + KL AV
Sbjct: 967 PPILGFKALMPS-----FCIRVNGEDETRLPTASTCVNLLKLPMYSTKQTLRDKLLTAVR 1021
Query: 812 ETIGFG 817
+GFG
Sbjct: 1022 SGVGFG 1027
>CE19147 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1066
Score = 173 bits (438), Expect = 1e-42
Identities = 121/405 (29%), Positives = 196/405 (47%), Gaps = 35/405 (8%)
Query: 445 FRRKVIYFRSQPALRILPGQCH--IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEE 502
FRR+V +++ A + Q I V+R I ED + + + T LK + +KF E+
Sbjct: 661 FRRQVQDDKNRVATSLNDPQMQTWITVQRNRIIEDGFNHLSKLTIPALKSTIRVKFVNEQ 720
Query: 503 GLDYGGVS-----REFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKF 557
GLD G+ +EF L ++F+P LF S + +P S ++ +HL F F
Sbjct: 721 GLDEAGIDQDGVFKEFLELTLKKVFDPQLNLF--STTSTGVLYPSPTSSLHDDHLALFTF 778
Query: 558 IGRVVGLGVFHRRFLDAFFVGALYKMML--RKKVVLQDMEGVDSEVYNSLKWILENSID- 614
+GR++G V+ +D L +L + ++ +D E+Y SL ++ +
Sbjct: 779 VGRMLGKAVYEGIVVDVQLAPVLLAAVLGSHRLCAFDELSQLDPELYRSLTFVKRYEGEM 838
Query: 615 GILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFM 674
L LTF+VD++ G++ VDL P+GR I VT+ENK +YV R+ R QEQ KAF+
Sbjct: 839 ADLSLTFSVDEDFMGKISTVDLVPSGRTISVTNENKIDYVHRMAHHRVFRRTQEQCKAFV 898
Query: 675 DGFNELVPEDLVNVFDERELELLIGGI-AEIDVEDWKKHTDY-RGYQESDEVIQWFWKCI 732
G ++ +++F +L+ LI G+ ++ID+ D K++ Y G+ + +I+W W +
Sbjct: 899 TGMQSILQPTWLSLFAPNDLQCLISGVNSDIDLADLKRNVQYFGGFHGNHRLIKWLWDIL 958
Query: 733 -TEWDNEQRARLLQFTTGTSRIPVNGFK--------------------DLQGSDGPRRFT 771
++ +E+R L+F T SR PV GF D GS
Sbjct: 959 ENKFTSEERKLFLKFVTSCSRPPVLGFSYLEPPFSIRCVEVSDDQDQGDTLGSVVRGFLA 1018
Query: 772 IEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
+ K +LP + TCFN + LP Y +KL A+ GF
Sbjct: 1019 LRKGTAATRLPTASTCFNLLKLPNYNKKSLLLEKLRYAIHAGTGF 1063
>At3g53090 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1142
Score = 172 bits (437), Expect = 1e-42
Identities = 109/372 (29%), Positives = 190/372 (50%), Gaps = 30/372 (8%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGL-----DYGGVSREFFFLLSHEM 521
I VRR ++ ED +Q++ LK + + F E GL DYGG+S+EF ++
Sbjct: 776 IVVRRGHVVEDGFQQL-NSIGSRLKSSIHVSFVNESGLPEAGLDYGGLSKEFLTDITKAA 834
Query: 522 FNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALY 581
F Y LF + + + +P++ + +F+GR+VG ++ LD F
Sbjct: 835 FATEYGLFSQTPTSDRLLVPSPSARHLENGIQMIEFLGRIVGKALYEGILLDYSFSHVFI 894
Query: 582 KMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILD---LTFNVDDERFGELVVVDLKP 638
+ +L + + ++ G+D E+Y +L ++ DG L L F V +E G++ +++LKP
Sbjct: 895 QKLLGRYSFIDELSGLDPELYRNLMYV--KHYDGDLKELCLDFTVTEEFCGKMSIIELKP 952
Query: 639 NGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDEREL-ELL 697
G++ VT+ENK +Y+ +++ ++ AF G +L+ + +F+ E +LL
Sbjct: 953 GGKDTSVTNENKMQYIHAMADYKLNRQIVPFSNAFYRGLTDLISPAWLKLFNAHEFNQLL 1012
Query: 698 IGGIAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVN 756
GG +IDV+D +++T Y GY +S I+ FW+ + ++ +R LL+F T SR P+
Sbjct: 1013 SGGNHDIDVDDLRRNTKYTGGYSDSSRTIKIFWEVMKGFEPSERCLLLKFVTSCSRAPLL 1072
Query: 757 GFKDLQGSDGPRRFTIEKAG------------EVQQLPKSHTCFNRVDLPPYTDYESFKQ 804
GFK LQ + F I K +V++LP + TC+N + LP Y + ++
Sbjct: 1073 GFKYLQPT-----FIIHKVSCDTSLWAAIGGQDVERLPSASTCYNTLKLPTYKRASTMRE 1127
Query: 805 KLTLAVEETIGF 816
KL A+ GF
Sbjct: 1128 KLLYAITSNAGF 1139
>ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase
Length = 746
Score = 172 bits (435), Expect = 2e-42
Identities = 109/353 (30%), Positives = 184/353 (51%), Gaps = 18/353 (5%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
I V R+ ++ DS + + D +K+L I F EEG+D GG+ +E+F LLS E+
Sbjct: 406 ITVSRETVYRDSIEIFKKINVLDARKQLRITFRNEEGVDSGGIRKEYFQLLSQEIKEDER 465
Query: 527 CLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLR 586
LFE H I I P+ G ++ IGR++ + +++ L+ F +K +L
Sbjct: 466 -LFE---HTENRIWIRPHEGDGEG----YEAIGRIIAIALYNNVVLNIPFPSLFFKKLLD 517
Query: 587 KKVVLQDMEGVDSEVYNSLKWILENSIDGI--LDLTFNVDDERFGELVVVDLKPNGREIE 644
++ L D+ + S + SL+ + S D + LDL F V+ G L NG +I+
Sbjct: 518 RRPTLDDLREISSGIATSLRNLRRLSRDEVDSLDLRFVVEHSVDGIPRSYPLVKNGEDIK 577
Query: 645 VTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEI 704
+T EN + ++E Y ++ ++ QF++ GF ++ +D + D +ELE ++ G
Sbjct: 578 LTSENMRLFIEKYVEFHTDALIKPQFESIKRGFYSIIDKDKLAYLDPKELEKIMMGSNTF 637
Query: 705 DVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGS 764
D++ + T Y G++E +I +FW+ ++ ++R +LLQF TG RIPV+G L
Sbjct: 638 DIKAIRSTTTYSGFREDSPIIVYFWEIFEAFNRKKRKKLLQFITGNDRIPVSGPASL--- 694
Query: 765 DGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
+ I + G + +LP S TCFN + LP Y+ + + KL A+E T GF
Sbjct: 695 ----KLVIMRNGCDTDRLPSSQTCFNTLLLPEYSSKDKLEGKLETALELTAGF 743
>YJR036c [O] KOG0941 E3 ubiquitin protein ligase
Length = 892
Score = 171 bits (434), Expect = 3e-42
Identities = 116/375 (30%), Positives = 189/375 (49%), Gaps = 31/375 (8%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
I+VRR I DS + I ++ DL K L I+F E G+D GG+ +E+FFLL+ +FNP
Sbjct: 523 IKVRRDVISHDSLRCI-KEHQGDLLKSLRIEFVNEPGIDAGGLRKEWFFLLTKSLFNPMN 581
Query: 527 CLFEY---SAHDNYTI---QINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGAL 580
LF Y S+ + I + + G N + Y+ F G V+GL +F+ LD F AL
Sbjct: 582 GLFIYIKESSRSWFAIDPPNFDKSKGKNSQLELYYLF-GVVMGLAIFNSTILDLQFPKAL 640
Query: 581 YKMMLRKKVVLQDMEGVDSEVYNSLKWIL---ENSIDGILDLTFNV----------DDER 627
YK + + + +D + E +L +L E++ + + LTF D +
Sbjct: 641 YKKLCSEPLSFEDYSELFPETSRNLIKMLNYTEDNFEDVFSLTFETTYRNNNWILNDSKS 700
Query: 628 FGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPE-DLV 686
E V V+L NGR + +T NK E+V + ++ + ++ Q+ F+ GF + E + +
Sbjct: 701 SKEYVTVELCENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSI 760
Query: 687 NVFDERELELLIGGIAE---IDVEDWKKHTDY-RGYQESDEVIQWFWKCITEWDNEQRAR 742
+F+ ELE L+ G E D + + T Y G+ + + WFW+ I WD + +
Sbjct: 761 KLFNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKK 820
Query: 743 LLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESF 802
LLQF T + RIP G + P + ++ + + LP +HTCFN + L Y+ +
Sbjct: 821 LLQFVTASDRIPATGISTI-----PFKISLLGSHDSDDLPLAHTCFNEICLWNYSSKKKL 875
Query: 803 KQKLTLAVEETIGFG 817
+ KL A+ E+ G+G
Sbjct: 876 ELKLLWAINESEGYG 890
>SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase
Length = 807
Score = 168 bits (425), Expect = 4e-41
Identities = 117/405 (28%), Positives = 194/405 (47%), Gaps = 40/405 (9%)
Query: 442 KRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGE 501
K + + + +F S + + IRVRR + EDS ++I + +D +K L ++F GE
Sbjct: 410 KMEIKAREAFFSSILSKMNVEPYLMIRVRRDRLLEDSLRQINDRN-KDFRKALKVEFLGE 468
Query: 502 EGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRV 561
EG+D GG+ RE+ LL+ ++F+P + LF + + N + + ++Y+ G +
Sbjct: 469 EGIDAGGLKREWLLLLTRKVFSPEFGLFVNCEESSNYLWFNYSH--RSKEIDYYHMSGIL 526
Query: 562 VGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWIL--ENSIDGILDL 619
+G+ + + LD A YK +L+ + D++ +Y LK +L E + L
Sbjct: 527 MGIAIHNSINLDVQMPRAFYKKLLQLPLSFNDLDDFQPSLYRGLKELLLFEGDVKNTYGL 586
Query: 620 TFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNE 679
F ++ + V+LK G E+ V +EN+KEYV Y + + V++QF AF DGF +
Sbjct: 587 NFTINLKAVEGFRTVELKEGGSELSVDNENRKEYVLRYVDYLLNTTVKKQFSAFFDGFMK 646
Query: 680 LVPEDLVNVFDERELELLIGGIAE-IDVEDWKKHTDYRGYQESD---------------- 722
+ + +++F + E+ LI G E ID E K Y Y ++
Sbjct: 647 VCGGNAISLFQDNEISKLIRGSEEVIDWELLKNVCVYDFYDQNAISNSISESEPSMTASK 706
Query: 723 ----------EVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTI 772
++I WFW I+ + + + L F TG+ RIP G + Q I
Sbjct: 707 YLCHSFVSKRKIILWFWDLISHYSLKMQKLFLIFVTGSDRIPATGAHNFQ-------LRI 759
Query: 773 EKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
G + QLP SHTCFN + + Y+ E K+KL A+ ET GF
Sbjct: 760 SVLGPDSDQLPISHTCFNHLCIWEYSSREKLKKKLDTALLETNGF 804
>7295004 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1078
Score = 164 bits (415), Expect = 5e-40
Identities = 112/389 (28%), Positives = 189/389 (47%), Gaps = 36/389 (9%)
Query: 462 PGQCHIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGL-----DYGGVSREFFFL 516
P I + R I ED Y+++ Q + LK + ++F ++GL D GV +EF
Sbjct: 689 PRSALIVIHRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEE 748
Query: 517 LSHEMFNPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFF 576
++F+P LF+ ++ + +P S + HL F+F+GR++G V+ +D F
Sbjct: 749 TIKKVFDPSLNLFKTTSDQR--LYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPF 806
Query: 577 VGALYKMMLRKKV-----VLQDMEGVDSEVYNSLKWILENSID-GILDLTFNVDDERFGE 630
+L + + ++ +D+E+Y SL +I D L+LTF+VD + G+
Sbjct: 807 ASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKHYKQDVSDLNLTFSVDQDVMGK 866
Query: 631 LVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFD 690
+V + L P G+ V D NK Y+ + + +++EQ AF GF +V + +++F
Sbjct: 867 IVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFS 926
Query: 691 ERELELLIGG-IAEIDVEDWKKHTD-YRGYQESDEVIQWFWKCIT-EWDNEQRARLLQFT 747
EL+ LI G + +D++D +KHT Y G+ ++ +V+ W W + ++ E+R L+F
Sbjct: 927 PPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFV 986
Query: 748 TGTSRIPVNGFKDLQ--------------------GSDGPRRFTIEKAGEVQQLPKSHTC 787
T S+ P+ GF L+ GS F I K + +LP S TC
Sbjct: 987 TSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTC 1046
Query: 788 FNRVDLPPYTDYESFKQKLTLAVEETIGF 816
FN + LP Y + + KL AV GF
Sbjct: 1047 FNLLKLPNYQKKSTLRDKLRYAVSSNTGF 1075
>Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1083
Score = 164 bits (414), Expect = 7e-40
Identities = 108/365 (29%), Positives = 189/365 (51%), Gaps = 22/365 (6%)
Query: 466 HIRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDG-----EEGLDYGGVSREFFFLLSHE 520
++ +RR I+ED+Y ++ + DLKKR+ + E G+D GG+ REF L
Sbjct: 724 NVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKS 783
Query: 521 MFNPFYCLFEYSAHDNYTIQINPNSG--INPEHLNYFKFIGRVVGLGVFHRRFLDAFFVG 578
FNP F+ + + + NP + + ++ F+ R++G ++ ++ F G
Sbjct: 784 GFNPNQGFFKTT--NEGLLYPNPAAQMLVGDSFARHYYFLARMLGKALYENMLVELPFAG 841
Query: 579 ALYKMMLRKK--VVLQDMEGVDSEVYNSLKWI--LENSIDGILDLTFNVDDERFGELVVV 634
+L V + + +D EVY +L ++ E+ ++ L L F V + GE VV
Sbjct: 842 FFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEE-LGLNFTVVNNDLGEAQVV 900
Query: 635 DLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDEREL 694
+LK G++I VT N+ Y+ L +R+ ++++ AF G +V + + +FD++E+
Sbjct: 901 ELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEI 960
Query: 695 ELLIGGI-AEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSR 752
++LI G I +ED K T+Y GY VI+ FW+ + + +E++ +LL+F T SR
Sbjct: 961 QVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSR 1020
Query: 753 IPVNGFKDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVE 811
P+ GFK+L + F I G ++++LP + TC N + LP + D + KL A+E
Sbjct: 1021 PPLLGFKELYPA-----FCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIE 1075
Query: 812 ETIGF 816
GF
Sbjct: 1076 CAAGF 1080
>YGL141w [O] KOG0942 E3 ubiquitin protein ligase
Length = 910
Score = 160 bits (404), Expect = 1e-38
Identities = 112/360 (31%), Positives = 181/360 (50%), Gaps = 22/360 (6%)
Query: 469 VRRKNIFEDSYQ---EIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMF-NP 524
+ R N+ ED++ I + L + +F E G+D GG+++EF +S E F +P
Sbjct: 558 ISRDNVLEDAFNAFNSIGERFKASLDVTFINEFGEEAGIDGGGITKEFLTTVSDEGFKDP 617
Query: 525 FYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMM 584
+ LF +D Y ++ P+ + L Y F+G+VVG ++ +D F K +
Sbjct: 618 KHELFR--TNDRY--ELYPSVVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKL 673
Query: 585 LRKK----VVLQDMEGVDSEVYNSLKWILENSIDGI--LDLTFNVDDERFGELVVVDLKP 638
L D+ DS +YN+L +L + D I LDLTF +D+ VVDL P
Sbjct: 674 LNYSNGFLSSFSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPE-SSAKVVDLIP 732
Query: 639 NGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLI 698
NG + VT +N YV T +++ R + AF G + ++ + +F+ EL++LI
Sbjct: 733 NGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLI 792
Query: 699 GGIAE-IDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNG 757
G + ID++D K +T+Y GY+E D+ I FW+ + E+ E++ L+F T + P+ G
Sbjct: 793 SGERDNIDLDDLKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQG 852
Query: 758 FKDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
FK L +F I AG E +LP + TC N + LP Y + ++KL A+ F
Sbjct: 853 FKALD-----PKFGIRNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARF 907
>CE29116 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1019
Score = 159 bits (401), Expect = 2e-38
Identities = 108/360 (30%), Positives = 178/360 (49%), Gaps = 22/360 (6%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+ VRR+ I D+ ++ + DL+K L + GE+ D GGV +EFF L+ ++ Y
Sbjct: 669 LTVRREFIVSDTMNQMAGLSESDLQKPLKVNIAGEDADDAGGVRKEFFILVMRKILQSDY 728
Query: 527 CLFEYSAHDNYTIQINPNSGINPEHLNYFKF--IGRVVGLGVFHRRFLDAFFVGALYKMM 584
+F +++ + SG+ E + +F +GR+VGL +++ + F ALYK +
Sbjct: 729 GMFSED-EESHLVWF---SGLPSEFCDREQFHQLGRLVGLSIYNHSIVPFPFPLALYKYL 784
Query: 585 LRKKVVLQDMEGVDSEVYNSLKWIL---ENSIDGILDLTFNVDDERFGELVVVDLKPNGR 641
L L+D+ + LK +L E+ ++ + L F + GE +L G
Sbjct: 785 LDTPPDLEDLCELSPSEGKGLKMLLSYEEDDVEDVFGLNFCISFNILGETHTTELLSGGT 844
Query: 642 EIEVTDENKKEYVELYTQWRIA----DRVQEQFKAFMDGFNELVPEDLVNVFDERELELL 697
E VT+ N+ EYV LY R+ + +Q F GF+E + + F EL+ +
Sbjct: 845 EKPVTNANRDEYVRLYVHHRLELGYNGEIAQQALLFRKGFSESLHSRTLRFFQPCELKEM 904
Query: 698 IGGIAEIDVEDWKKHTDYRG-YQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVN 756
I G D +++ YRG Y S IQ FWK +++R + LQF TG++RIPV+
Sbjct: 905 IVGNENYDWNEFRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFLTGSTRIPVS 964
Query: 757 GFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
G+++L + P + LP +HTCFN +DLP D ++L +++E T GF
Sbjct: 965 GWEELHAAIQP--------SAPESLPVAHTCFNLLDLPNIADDVELLRRLRISIEHTEGF 1016
>Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1024
Score = 155 bits (391), Expect = 3e-37
Identities = 104/356 (29%), Positives = 178/356 (49%), Gaps = 19/356 (5%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+ VRR ++ ED ++ + EDL+K L + F GE G D GGV +EFF+ L EM P Y
Sbjct: 683 LTVRRNHLIEDVLNQLSQFENEDLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQPEY 742
Query: 527 CLFEY-SAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMML 585
+F Y + P E YF F G + GL +F+ + F AL+K +L
Sbjct: 743 GMFMYPEGASCMWFPVKPKF----EKKRYF-FFGVLCGLSLFNCNVANLPFPLALFKKLL 797
Query: 586 RKKVVLQDMEGVDSEVYNSLKWILENSIDG---ILDLTFNVDDERFGELVVVDLKPNGRE 642
+ L+D++ + ++ +L+ +L++ D + + FNV +R +L PNG
Sbjct: 798 DQMPSLEDLKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNVHWDRND----TNLIPNGSS 853
Query: 643 IEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIA 702
I V NK++YV Y + D V+ ++ F GF ++ ED++ +F EL+ +I G
Sbjct: 854 ITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNT 913
Query: 703 EIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDL 761
+ D + ++K+ Y GY S I FWK + E++ + L F TGT R+ + ++
Sbjct: 914 DYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNM 973
Query: 762 QGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFG 817
+ + F ++ + ++ TCF+ + LP Y+ E+ ++ L A+ GFG
Sbjct: 974 KIT-----FCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG 1024
>CE15744 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1001
Score = 154 bits (388), Expect = 7e-37
Identities = 105/370 (28%), Positives = 182/370 (48%), Gaps = 26/370 (7%)
Query: 467 IRVRRKNIFEDSYQ----EIMRQTPEDLKKRLMIKFDG-----EEGLDYGGVSREFFFLL 517
+ VRR ++ D+++ ++ DLK + +K E G+D GG+ REF L
Sbjct: 635 VTVRRDQVYMDAFETFAPKMQGDKVNDLKSMVRVKMVNWAGMNESGIDGGGIFREFLSEL 694
Query: 518 SHEMFNPFYCLFEYSAHDNYTIQINPNSG--INPEHLNYFKFIGRVVGLGVFHRRFLDA- 574
FN F ++ ++ + NP + + + L +F+FIGR++G ++ R+ +
Sbjct: 695 LKTAFNVERGFFTFT--ESKLLYPNPTAPFLLGVDCLAHFQFIGRMIGKLIYERQLQEVR 752
Query: 575 ---FFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWI--LENSIDGILDLTFNVDDERFG 629
FF+ +++ K V LQ M+ D ++ LK + + N L L F+V G
Sbjct: 753 FAEFFIAQIFETDKNKDVDLQHMKSFDPIIFKHLKALQKMNNRELDELQLDFSVVTSDMG 812
Query: 630 ELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVF 689
+ V+LKPNG + VT EN EYV LY + + R+ A G +E++ + + +F
Sbjct: 813 LVRNVNLKPNGSKFRVTVENVHEYVRLYVNYHLKQRIASMVDAVRKGISEIISIEWMRMF 872
Query: 690 DERELELLIGGIAEI-DVEDWKKHTDYRGYQESDEV--IQWFWKCITEWDNEQRARLLQF 746
EL+++I G E+ ++ +K + R + ++ + FW I + N+ + LL+F
Sbjct: 873 APHELQIMIAGYEEVFTAKELRKFCELRFAAGTQDINYEEMFWDVIDKLSNDDKKALLKF 932
Query: 747 TTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKL 806
TG SR PV+GFK +Q PR + +LP S TC N + +P Y++ ++KL
Sbjct: 933 VTGCSRAPVDGFKSIQ----PRMGVLVIPSSDDELPTSATCMNMLRIPKYSNRTKLEEKL 988
Query: 807 TLAVEETIGF 816
A+ GF
Sbjct: 989 RYAINSGAGF 998
>Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase
Length = 218
Score = 144 bits (362), Expect = 7e-34
Identities = 75/211 (35%), Positives = 120/211 (56%), Gaps = 8/211 (3%)
Query: 610 ENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQ 669
E +++ TF V E FG + +LKP G +I VT++N+KEYV+LYT + + + +Q
Sbjct: 15 EGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQ 74
Query: 670 FKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFW 729
F AF GF+ + + + + E+E+L+ G ++D+ ++ T Y GY ++D I++FW
Sbjct: 75 FAAFYYGFHSVCASNALMLLRPEEVEILVCGSPDLDMHALQRSTQYDGYAKTDLTIKYFW 134
Query: 730 KCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEK-AGEVQQLPKSHTCF 788
+ + + + +LL FTTG+ R+PV G DL F I K LP +HTCF
Sbjct: 135 DVVLGFPLDLQKKLLHFTTGSDRVPVGGMADL-------NFKISKNETSTNCLPVAHTCF 187
Query: 789 NRVDLPPYTDYESFKQKLTLAVEETIGFGQE 819
N++ LPPY + KQKL + + + GFG E
Sbjct: 188 NQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 218
>Hs4557026 [S] KOG1426 FOG: RCC1 domain
Length = 4861
Score = 142 bits (357), Expect = 3e-33
Identities = 103/355 (29%), Positives = 174/355 (49%), Gaps = 23/355 (6%)
Query: 472 KNIFEDSYQEIMRQTPEDLK---KRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCL 528
K IF +++++ DL+ + +K GE D GGV + + E+ L
Sbjct: 4487 KPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGIVDL 4546
Query: 529 FEYSAHDNYTIQINPNSGI-NP-----EHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYK 582
S + + N + + NP EHL FKF+G ++G+ + ++ LD ++K
Sbjct: 4547 LIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWK 4606
Query: 583 MMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVD---DERFGELV---VVDL 636
+ + L+D+E VD +L IL GI + +F+ D G+ +V +
Sbjct: 4607 QLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPI 4666
Query: 637 KPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELEL 696
P G I +T N+KEYVE ++R+ + + Q A +G + +VP L+++ ++LE
Sbjct: 4667 IPGGNSIPLTFSNRKEYVERAIEYRLHE-MDRQVAAVREGMSWIVPVPLLSLLTAKQLEQ 4725
Query: 697 LIGGIAEIDVEDWKKHTDYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVN 756
++ G+ EI VE KK YR E +++QWFW + E+ NE+R ++F +G SR+P N
Sbjct: 4726 MVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPAN 4785
Query: 757 GFKDLQGSDGPRRFTIEKAGE-VQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAV 810
+D +RF I K LP S TCF ++ LPPY+ ++L A+
Sbjct: 4786 ------TADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAI 4834
>Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase
Length = 379
Score = 141 bits (356), Expect = 4e-33
Identities = 102/354 (28%), Positives = 177/354 (49%), Gaps = 17/354 (4%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+RVRR + +D+ +++ + D K L+++F E + GGVS EFF + EM P Y
Sbjct: 31 LRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESGGVSSEFFHCMFEEMTKPEY 90
Query: 527 CLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLR 586
+F Y + + P + PE YF F G + GL +F+ + F ALYK +L
Sbjct: 91 GMFMYP--EMCSCMWFP-AKPKPEKKRYFLF-GMLCGLSLFNLNVANLPFPLALYKKLLD 146
Query: 587 KKVVLQDMEGVDSEVYNSLKWILENSIDGILD---LTFNVDDERFGELVVVDLKPNGREI 643
+K L+D++ + + SL+ +L+++ D I D + F++ ++ VDL PNG I
Sbjct: 147 QKPSLEDLKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQND----VDLIPNGISI 202
Query: 644 EVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAE 703
V NK++YV Y + V+ ++ F GF + ++++ F EL I G +
Sbjct: 203 PVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTD 262
Query: 704 IDVEDWKKHTDY-RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQ 762
D + +++++ Y +GYQ+S IQ FWK + +++ + L F TG R+ G + ++
Sbjct: 263 YDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKME 322
Query: 763 GSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGF 816
F + + P S TC N + LP Y+ E ++ L +A+ GF
Sbjct: 323 -----IVFRCPETFSERDHPTSITCHNILSLPKYSTMERMEEALQVAINNNRGF 371
>Hs4758520 [S] KOG1426 FOG: RCC1 domain
Length = 4834
Score = 107 bits (267), Expect = 7e-23
Identities = 84/329 (25%), Positives = 150/329 (45%), Gaps = 25/329 (7%)
Query: 496 IKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAHD------NYTIQINPNSGINP 549
+KF GE D GG E + E+ N L + + N + + P
Sbjct: 4468 VKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLSPAARAP 4527
Query: 550 EHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWIL 609
H + F+F+G ++G+ + L ++K + + + D+ VD + L +I
Sbjct: 4528 VHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIR 4587
Query: 610 ENSIDG----ILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADR 665
+N + L F V G+ D++ + + +T +N+ EYV L +R+ +
Sbjct: 4588 DNEATSEEFEAMSLPFTVPSAS-GQ----DIQLSSKHTHITLDNRAEYVRLAINYRLHE- 4641
Query: 666 VQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDYRGYQESDEVI 725
EQ A +G +VP L+++F ELE ++ G +I + K Y+G + S +I
Sbjct: 4642 FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLI 4701
Query: 726 QWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQ----L 781
QWFW+ + + N +R+ L+F G +R+P D +G D F I+ + L
Sbjct: 4702 QWFWEVMESFSNTERSLFLRFVWGRTRLP-RTIADFRGRD----FVIQVLDKYNPPDHFL 4756
Query: 782 PKSHTCFNRVDLPPYTDYESFKQKLTLAV 810
P+S+TCF + LP Y+ + ++KL A+
Sbjct: 4757 PESYTCFFLLKLPRYSCKQVLEEKLKYAI 4785
>Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 650
Score = 105 bits (263), Expect = 2e-22
Identities = 82/292 (28%), Positives = 134/292 (45%), Gaps = 38/292 (13%)
Query: 555 FKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVL--QDMEGVD-------------- 598
F+F+G+++ + R +D YK MLR++ L D+ +D
Sbjct: 355 FRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIV 414
Query: 599 ----------SEVYNSLKWILEN-SIDG--ILDLTFNVDDERFGELVVVDLKPNGREIEV 645
S+ SL++ LE +++G + DL + F ++LK G++I V
Sbjct: 415 RQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFPN---IELKKGGKDIPV 471
Query: 646 TDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEID 705
T N +EY+ L W + + V QF +F DGF + P + F EL+ L+ G ++ D
Sbjct: 472 TIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCG-SKAD 530
Query: 706 VEDWKKHTDY----RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDL 761
D K + GY +++ ++ ++ +DNEQ+ LQF TG+ R+PV GF+ L
Sbjct: 531 TWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSL 590
Query: 762 QGSDGPRRFTIEKAGEVQQ-LPKSHTCFNRVDLPPYTDYESFKQKLTLAVEE 812
R T E LP TC N + LP Y+ E ++KL +A E
Sbjct: 591 NPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAARE 642
>Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2799
Score = 105 bits (261), Expect = 4e-22
Identities = 80/293 (27%), Positives = 142/293 (48%), Gaps = 29/293 (9%)
Query: 543 PNSGINPE-HLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEV 601
P G N E LN F+ IGR++GL + + K++L +KV D D +
Sbjct: 2516 PRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVM 2575
Query: 602 YNSLKWIL-------ENSIDGILDLTFNVD---DERFGELVVVDLKPNGREIEVTDENKK 651
Y SL+ ++ +++ +DL F +D +E G+ V+L PNG I VT +N
Sbjct: 2576 YESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQ---VELIPNGVNIPVTPQNVY 2632
Query: 652 EYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKK 711
EYV Y + R+ ++ A G +++P++ + + LL+ G E++V+
Sbjct: 2633 EYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLIS 2692
Query: 712 HTDY--RGYQESDEVIQ---WFWKCITEWDNEQRARLLQFTTGTSRIPVN--GFKDLQGS 764
T + + +++++Q WFW + + +R L+ F T + +P + GF+ +
Sbjct: 2693 FTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPS- 2751
Query: 765 DGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIGFG 817
TI + Q LP ++TC +R+ +P Y+ + KQKL LA+ +T FG
Sbjct: 2752 -----ITIRPPDD-QHLPTANTCISRLYVPLYSSKQILKQKLLLAI-KTKNFG 2797
>At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 628
Score = 104 bits (260), Expect = 5e-22
Identities = 106/430 (24%), Positives = 183/430 (41%), Gaps = 53/430 (12%)
Query: 429 RLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIRVRRKNIFEDSYQEIMRQTPE 488
RL + Q + + + ++ ++P LP + + R +NI E + + M +
Sbjct: 204 RLAAFGSQKIRHHPQHLSSSNVHGEARPVTGSLPRKKFLACR-ENILESAAK--MMELYG 260
Query: 489 DLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY------CLFEYSAHDNYTIQIN 542
+ K + +++ E G G + EF+ L+S NP C F ++ +
Sbjct: 261 NQKVVIEVEYSEEVGTGLGP-TLEFYTLVSRAFQNPDLGMWRNDCSFIVGKPVEHSGVLA 319
Query: 543 PNSGINP----------EHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQ 592
+SG+ P + L F +G VV + R LD A YK++L +++
Sbjct: 320 SSSGLFPRPWSGTSTTSDVLQKFVLLGTVVAKALQDGRVLDLPLSKAFYKLILGQELSSF 379
Query: 593 DMEGVDSEVYNSL----------KWILENSID-GILDLTFNVDDERFGELVV-------- 633
D+ VD E+ +L K E D G + + +L +
Sbjct: 380 DIHFVDPELCKTLVELQALVRRKKLFAEAHGDSGAAKCDLSFHGTKIEDLCLEFALPGYT 439
Query: 634 -VDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDER 692
DL P V +N +EY++ + + +Q+Q +AF GFN++ + + +F+E
Sbjct: 440 DYDLAPYSANDMVNLDNLEEYIKGIVNATVCNGIQKQVEAFRSGFNQVFSIEHLRIFNEE 499
Query: 693 ELELLIGGIAEIDVEDWKKHTDY----RGYQESDEVIQWFWKCITEWDNEQRARLLQFTT 748
ELE ++ G E D+ + D+ GY S +++ + + E+D EQ+ LQF T
Sbjct: 500 ELETMLCG--ECDLFSMNEVLDHIKFDHGYTSSSPPVEYLLQILHEFDREQQRAFLQFVT 557
Query: 749 GTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQ---QLPKSHTCFNRVDLPPYTDYESFKQK 805
G+ R+P G L P+ + K G LP TC N + LPPY+ E K+K
Sbjct: 558 GSPRLPHGGLASL----SPKLTIVRKHGSDSSDTDLPSVMTCANYLKLPPYSSKEKMKEK 613
Query: 806 LTLAVEETIG 815
L A+ E G
Sbjct: 614 LIYAITEGQG 623
>CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2944
Score = 100 bits (250), Expect = 7e-21
Identities = 75/301 (24%), Positives = 146/301 (47%), Gaps = 16/301 (5%)
Query: 523 NPFYCLFEYSAHDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYK 582
+P LFE + + + + N P L ++ +GR++G+ + F ++
Sbjct: 2652 SPLDQLFEKAPYGEFYVPKIGNGA--PMRLAAYRTVGRIMGICLSQGDIFPLRFSRHIFS 2709
Query: 583 MMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFN-VDDERFGELVVVDLKPNGR 641
+L+ + D+ D ++N+L+ + + + LD F+ V+ G+ V V+LKPNG
Sbjct: 2710 YILKLPICWLDLGFYDPVLFNNLRALFK-AHPSELDTDFSIVEQSADGKAVTVNLKPNGD 2768
Query: 642 EIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGI 701
E+ V +N EYV Y + + + F+A +G +++PE ++ +L L+I GI
Sbjct: 2769 EVLVNKDNVIEYVYKYAERVLVGKRIITFEAIREGILDVIPESMLFGLTPEDLRLIICGI 2828
Query: 702 AEIDVEDWKKHTDY----RGYQES-DEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVN 756
+ + +++T + R QE+ + QWFW+ I + +++ L+ F TG+ +P
Sbjct: 2829 ESVSISVLQENTGFLDESRASQETLNRFKQWFWQVIESFTQQEKQELVFFWTGSPALPAA 2888
Query: 757 GFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVE-ETIG 815
G S + + E LP ++TC +R+ +P Y+ + KL LA++ + G
Sbjct: 2889 GKWPTSAS------VMLRPQEDVFLPTANTCISRLYVPVYSSKRVLRTKLLLAIKAKNFG 2942
Query: 816 F 816
F
Sbjct: 2943 F 2943
>YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 470
Score = 97.1 bits (240), Expect = 1e-19
Identities = 103/404 (25%), Positives = 170/404 (41%), Gaps = 83/404 (20%)
Query: 467 IRVRRKNIFEDSYQEIMR--QTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLS----HE 520
+R+ RK IF + + + +P+ L+ I++ E G G + EF+ ++S +
Sbjct: 90 LRISRKTIFATGLKILSKYGSSPDVLE----IEYQEEAGTGLGP-TLEFYSVVSKYFARK 144
Query: 521 MFNPFYC-LFEYSAH------DNYTIQI------NPNSGINPEHLNYFKFIGRVVGLGVF 567
N + C + Y + D+Y + NP S N + + F ++G V +
Sbjct: 145 SLNMWRCNSYSYRSEMDVDTTDDYITTLLFPEPLNPFSN-NEKVIELFGYLGTFVARSLL 203
Query: 568 HRRFLDAFFVGALYKMMLRK------------KVVLQDMEGVDSEVYNSLKWILENSIDG 615
R LD F ++++ R + L +E VD + SLK+I+ N D
Sbjct: 204 DNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKDDN 263
Query: 616 I----LDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFK 671
+ L LTF V EL+ P G + N +EY+ + +++Q K
Sbjct: 264 MTLESLSLTFTVPGNDDIELI-----PGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLK 318
Query: 672 AFMDGFNE---------LVPEDLVNVFDERELELLIGGIAEIDVEDWKKHTDY------R 716
AF++GF++ L P++LV++F E EDW T Y
Sbjct: 319 AFIEGFSKVFSYERMLILFPDELVDIFGRVE-------------EDWSMATLYTNLNAEH 365
Query: 717 GYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAG 776
GY +I F I+ + +R LQF TG+ ++P+ GFK L P+ + K
Sbjct: 366 GYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSL----NPKFTVVLKHA 421
Query: 777 E-----VQQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIG 815
E + LP TC N + LP YT + + +L A+EE G
Sbjct: 422 EDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAG 465
>7297647 [R] KOG4276 Predicted hormone receptor interactor
Length = 2727
Score = 92.8 bits (229), Expect = 2e-18
Identities = 72/248 (29%), Positives = 113/248 (45%), Gaps = 15/248 (6%)
Query: 576 FVGALYKMMLRKKVV-LQDMEGVDS--EVYNSLKWILENSIDGILD---LTFN-VDDERF 628
F+ + ++LRK+ + D + E+ N LK +N ++ L+ LTF +
Sbjct: 2478 FLQEMQNLLLRKQSIEFDDTISAEKKHELINELKLQTQNGLEVSLEDLALTFTYLPSSSI 2537
Query: 629 GELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNV 688
+L PNG + VT +N + Y EL + + D + +Q KAF DGFNE+ P +
Sbjct: 2538 YGYTQAELLPNGSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAA 2597
Query: 689 FDERELELLIGG--IAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRARLLQ 745
F E ++I G ED +T+ + GY + Q F + ++R LQ
Sbjct: 2598 FTPSEARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLLSMSGDERKAFLQ 2657
Query: 746 FTTGTSRIPVNGFKDLQGSDGPRRFTIEKA-GEVQQLPKSHTCFNRVDLPPYTDYESFKQ 804
FTTG S +P G +L PR + K V P +TC + + LP Y E K+
Sbjct: 2658 FTTGCSSLPPGGLANLH----PRLTVVRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMKE 2713
Query: 805 KLTLAVEE 812
+L A +E
Sbjct: 2714 RLLTATKE 2721
>Hs15300020 [R] KOG4276 Predicted hormone receptor interactor
Length = 1592
Score = 88.2 bits (217), Expect = 5e-17
Identities = 65/252 (25%), Positives = 118/252 (46%), Gaps = 17/252 (6%)
Query: 574 AFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDG------ILDLTFNVD--- 624
A F+ + + ++++ +L + + E L+ ++ + G I DL N
Sbjct: 1339 ARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCP 1398
Query: 625 DERFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPED 684
R VDLKP+G + +T +N +EYV+L + + +Q+Q +AF DGFN++ P +
Sbjct: 1399 SSRIYGFTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPME 1458
Query: 685 LVNVFDERELELLIGGIAEID--VEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRA 741
++ F E+++++ G ED +T+ + GY F + + +++R
Sbjct: 1459 KLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERK 1518
Query: 742 RLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQ-QLPKSHTCFNRVDLPPYTDYE 800
LQFTTG S +P G +L PR + K P +TC + + LP Y+ E
Sbjct: 1519 AFLQFTTGCSTLPPGGLANLH----PRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEE 1574
Query: 801 SFKQKLTLAVEE 812
+++L A E
Sbjct: 1575 IMRERLLAATME 1586
>SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase
Length = 400
Score = 86.3 bits (212), Expect = 2e-16
Identities = 93/380 (24%), Positives = 157/380 (40%), Gaps = 46/380 (12%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
IR+ RK IF +Y + T + L I+++ E G G + EF+ +S E
Sbjct: 31 IRISRKKIF--NYALHLLATYAASENILEIEYEDEVGSGLGP-TLEFYTSVSKEFTLNSL 87
Query: 527 CL---------FEYSAHDNYTIQINPNSGINPEH---LNYFKFIGRVVGLGVFHRRFLDA 574
+ F Y A + I P G +PE+ ++ F +G+ V ++ R +
Sbjct: 88 DIWRNDQPNSKFVYQASGLFPSPI-PLLGSSPENERKISLFFALGQFVARSIYDSRIISI 146
Query: 575 FFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWILENSIDGILDLTFNVD--------DE 626
F + + + + + VD + NSL++ LE I G D D
Sbjct: 147 QFNPLFFARNI--PLTISSVAKVDKGLANSLRY-LEKLIPGKNPTNAETDIKLEDLHLDF 203
Query: 627 RFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDLV 686
++L P+G VT N +Y+ + + VQ+Q +AF +GF+ + P +
Sbjct: 204 TLPGFPSIELIPDGASTPVTTFNVSDYLNYVIDYTVGKGVQQQLEAFQNGFSSVFPYTSL 263
Query: 687 NVFDERELELLIGGIAEIDVEDWKKHTDYR------GYQESDEVIQWFWKCITEWDNEQR 740
V E EL L G + EDW T + GY IQ +++ + +++
Sbjct: 264 QVLTEHELVTLFGTVD----EDWSYATLMKSIVADHGYTMESPTIQRLLTLMSQMNFQEQ 319
Query: 741 ARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSH-----TCFNRVDLPP 795
LQF TG+ ++P+ GF L P + + E +P + TC N + LP
Sbjct: 320 RDFLQFITGSRKLPIGGFAGL----NPPLTVVRRLNEPPYVPDDYLPSVMTCVNYLKLPE 375
Query: 796 YTDYESFKQKLTLAVEETIG 815
Y+ E +L+ A+ E G
Sbjct: 376 YSSSEVLGSRLSKAILEGQG 395
>Hs13375805 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 210
Score = 86.3 bits (212), Expect = 2e-16
Identities = 61/218 (27%), Positives = 108/218 (48%), Gaps = 26/218 (11%)
Query: 594 MEGVDSEVYNSLKWILENSIDGILDLTFNVDDERFGELVVVDLKPNGREIEVTDENKKEY 653
MEG+D E + E L T + D++ VV+L P G I V ++ +
Sbjct: 1 MEGMDKETF-------EFKFGKELTFTTVLSDQQ-----VVELIPGGAGIVVGYGDRSRF 48
Query: 654 VELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEIDVEDWKKHT 713
++L + R+ + +EQ A G ++VP+ ++++ +ELE + G E+ V+ +K T
Sbjct: 49 IQLVQKARLEES-KEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLT 107
Query: 714 DYRGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIP--VNGFKDLQGSDGPRRFT 771
+ ++ SD +Q+FW+ + + NE R+R L+F TG SR+P + + D G +
Sbjct: 108 RFEDFEPSDSRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYIYPDKLGYE------ 161
Query: 772 IEKAGEVQQLPKSHTCFNRVDLPPYTDYESFKQKLTLA 809
LP+S TC + + LP Y + ++KL A
Sbjct: 162 -----TTDALPESSTCSSTLFLPHYASAKVCEEKLRYA 194
>At4g38600 [O] KOG0170 E3 ubiquitin protein ligase
Length = 757
Score = 83.6 bits (205), Expect = 1e-15
Identities = 103/419 (24%), Positives = 168/419 (39%), Gaps = 81/419 (19%)
Query: 467 IRVRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFY 526
+RV R I DS ++M K L +++ GE G G + EF+ LLSH++
Sbjct: 345 VRVSRNRIL-DSAAKVMEMYSSQ-KAVLEVEYFGEVGTGLGP-TLEFYTLLSHDLQKASL 401
Query: 527 CLFEYSAHDNYTIQINPNS------------------GINPEH----------------L 552
++ S+ D ++QI + G+ P +
Sbjct: 402 GMWRSSSGDKVSMQIGRDEIEDGKPSAANRDIVLAPLGLFPRPWPSTADISEGGQFHKVI 461
Query: 553 NYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDSEVYNSLKWIL--- 609
YF+ +GRV+ + R LD A YK++L +++ L D+ D+E+ +L+ +
Sbjct: 462 EYFRLLGRVMAKALQDGRLLDVPLSTAFYKLILGQELDLHDIVLFDAELGKTLQELRVVV 521
Query: 610 --ENSIDGIL-DLTFNVDDERFGELVVVDLK-------------PNGREIEVTDENKKEY 653
++ ++G+ D + + D + DL +G EI V N +EY
Sbjct: 522 ARKHYLEGVGGDNSSTISDLCLRGCRIEDLSLEFTLPGYPEYILRSGDEI-VDITNLEEY 580
Query: 654 VELYTQWRIADRVQEQFKAFMDGFNELVPEDLVNVFDERELELLIGGIAEI-DVEDWKKH 712
+ L + V Q +AF GFN++ + +F EL+ L+ G E+ +VE +H
Sbjct: 581 ISLVVDATVKRGVTRQIEAFRSGFNQVFDITSLQIFTPSELDYLLCGRRELWEVETLAEH 640
Query: 713 TDY-RGYQESDEVIQWFWKCITEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFT 771
+ GY I C ++QRA QF TG R+P G L P+
Sbjct: 641 IKFDHGYNAKSPAI--INVCYPSSSDQQRA-FCQFVTGAPRLPPGGLAVL----NPKLTI 693
Query: 772 IEKAGEV---------------QQLPKSHTCFNRVDLPPYTDYESFKQKLTLAVEETIG 815
+ K LP TC N + LPPY+ E +KL A+ E G
Sbjct: 694 VRKHSSTSSAAANGAGASETADDDLPSVMTCANYLKLPPYSTKEIMYKKLLYAINEGQG 752
>Hs18860882 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 311
Score = 74.3 bits (181), Expect = 7e-13
Identities = 47/145 (32%), Positives = 61/145 (41%), Gaps = 33/145 (22%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G Y+ +H T W P+ + R G LP
Sbjct: 17 ELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRV---------------AGDLPY 61
Query: 402 GWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQ-----------------YKRD 444
GWE +V+FVDH K TT+ DPRL ++D N + RD
Sbjct: 62 GWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRD 121
Query: 445 FRRKVIYFRSQPALRILPGQCHIRV 469
F KV+ + I G CH RV
Sbjct: 122 FTGKVVVVTGANS-GIATGSCHHRV 145
>Hs7706523 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 414
Score = 73.6 bits (179), Expect = 1e-12
Identities = 44/123 (35%), Positives = 59/123 (47%), Gaps = 19/123 (15%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G Y+ +H T W P+ + R G LP
Sbjct: 17 ELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRV---------------AGDLPY 61
Query: 402 GWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRIL 461
GWE +V+FVDH K TT+ DPRL ++D N K R++ Y S A+ IL
Sbjct: 62 GWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDN--PTKPTTRQR--YDGSTTAMEIL 117
Query: 462 PGQ 464
G+
Sbjct: 118 QGR 120
>Hs18860886 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 213
Score = 73.6 bits (179), Expect = 1e-12
Identities = 44/123 (35%), Positives = 59/123 (47%), Gaps = 19/123 (15%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G Y+ +H T W P+ + R G LP
Sbjct: 17 ELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRV---------------AGDLPY 61
Query: 402 GWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRIL 461
GWE +V+FVDH K TT+ DPRL ++D N K R++ Y S A+ IL
Sbjct: 62 GWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDN--PTKPTTRQR--YDGSTTAMEIL 117
Query: 462 PGQ 464
G+
Sbjct: 118 QGR 120
>Hs18860884 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 189
Score = 73.6 bits (179), Expect = 1e-12
Identities = 44/123 (35%), Positives = 59/123 (47%), Gaps = 19/123 (15%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G Y+ +H T W P+ + R G LP
Sbjct: 17 ELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRV---------------AGDLPY 61
Query: 402 GWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRIL 461
GWE +V+FVDH K TT+ DPRL ++D N K R++ Y S A+ IL
Sbjct: 62 GWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDN--PTKPTTRQR--YDGSTTAMEIL 117
Query: 462 PGQ 464
G+
Sbjct: 118 QGR 120
>Hs18860880 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 234
Score = 73.6 bits (179), Expect = 1e-12
Identities = 44/123 (35%), Positives = 59/123 (47%), Gaps = 19/123 (15%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G Y+ +H T W P+ + R G LP
Sbjct: 17 ELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRV---------------AGDLPY 61
Query: 402 GWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRIL 461
GWE +V+FVDH K TT+ DPRL ++D N K R++ Y S A+ IL
Sbjct: 62 GWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDN--PTKPTTRQR--YDGSTTAMEIL 117
Query: 462 PGQ 464
G+
Sbjct: 118 QGR 120
>Hs13699258 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 363
Score = 73.6 bits (179), Expect = 1e-12
Identities = 44/123 (35%), Positives = 59/123 (47%), Gaps = 19/123 (15%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G Y+ +H T W P+ + R G LP
Sbjct: 17 ELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRV---------------AGDLPY 61
Query: 402 GWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRIL 461
GWE +V+FVDH K TT+ DPRL ++D N K R++ Y S A+ IL
Sbjct: 62 GWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDN--PTKPTTRQR--YDGSTTAMEIL 117
Query: 462 PGQ 464
G+
Sbjct: 118 QGR 120
>Hs9257195 [R] KOG3209 WW domain-containing protein
Length = 1256
Score = 73.2 bits (178), Expect = 2e-12
Identities = 35/107 (32%), Positives = 56/107 (51%), Gaps = 3/107 (2%)
Query: 340 LGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPR---RQQYIRTYGPSTNTIQQQPVSQL 396
LG LP WE +T G YF+DHNT+TT+W+DPR +QQ + + +
Sbjct: 299 LGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSE 358
Query: 397 GPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKR 443
LP+GWE +Y+VDH + T +++P L + + + Q ++
Sbjct: 359 LELPAGWEKIEDPVYGIYYVDHINRKTQYENPVLEAKRKKQLEQQQQ 405
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/50 (56%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 383 PSTNTIQQQPVS---QLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPR 429
PS Q P+S LGPLP WEM T VYF+DHNTKTT+W DPR
Sbjct: 283 PSQKFPQYLPLSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWLDPR 332
>CE17508 [R] KOG4276 Predicted hormone receptor interactor
Length = 2761
Score = 70.1 bits (170), Expect = 1e-11
Identities = 62/251 (24%), Positives = 110/251 (43%), Gaps = 22/251 (8%)
Query: 576 FVGALYKMMLRKKVVLQDMEGVDSEVYN----SLKWILENSIDGILDLTFNVDDE----- 626
F+ L + RK+++ D +DS LK ++ S + DL N
Sbjct: 2513 FLKELRALAQRKRLIENDTS-IDSNSKRRKIAELKLHIKGSTCRVEDLALNFTVNPPSKV 2571
Query: 627 -RFGELVVVDLKPNGREIEVTDENKKEYVELYTQWRIADRVQEQFKAFMDGFNELVPEDL 685
++ E+ +VD G +I+VT +N ++YVE ++ + + Q +AF DGF+ + P
Sbjct: 2572 FQYAEMELVD---GGSDIDVTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRT 2628
Query: 686 VNVFDERELELLIGG--IAEIDVEDWKKHTDYR-GYQESDEVIQWFWKCITEWDNEQRAR 742
+ + E++ L+ G E +D +T+ + GY F + ++R
Sbjct: 2629 LRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKN 2688
Query: 743 LLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQ-QLPKSHTCFNRVDLPPYTDYES 801
LQF TG S +P G +L PR + K P +TC + + LP Y+
Sbjct: 2689 FLQFATGCSSLPPGGLANLH----PRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAI 2744
Query: 802 FKQKLTLAVEE 812
+++L A+ E
Sbjct: 2745 LRERLLTAINE 2755
>7291247 [R] KOG3209 WW domain-containing protein
Length = 922
Score = 67.8 bits (164), Expect = 6e-11
Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 13/93 (13%)
Query: 340 LGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQL--G 397
LG LPP WE +T G YF+DHNT T+ W+DPR +Y Q++ +
Sbjct: 48 LGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKY-----------QKKSLEDCCED 96
Query: 398 PLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRL 430
LP GWE + +YF+DH + T +++P L
Sbjct: 97 ELPYGWEKIEDSMYGMYFIDHVNRRTQYENPVL 129
>Hs6912462 [R] KOG3209 WW domain-containing protein
Length = 1455
Score = 62.4 bits (150), Expect = 3e-09
Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 10/88 (11%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LP WE +T +G YF+DHNT+TT+W+DPR + + P + + LP G
Sbjct: 304 LPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAK---PPEECKENE-------LPYG 353
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDPRL 430
WE Y+VDH + T +++P L
Sbjct: 354 WEKIDDPIYGTYYVDHINRRTQFENPVL 381
Score = 55.1 bits (131), Expect = 4e-07
Identities = 22/33 (66%), Positives = 24/33 (72%)
Query: 398 PLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRL 430
PLP WEM T VYF+DHNTKTT+W DPRL
Sbjct: 303 PLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRL 335
>Hs13346498 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 400
Score = 59.7 bits (143), Expect = 2e-08
Identities = 37/122 (30%), Positives = 54/122 (43%), Gaps = 9/122 (7%)
Query: 261 NTRTTTWKRPTLDQSEVQRVNTELERRQ--------HRGRTLPDGGAQSEGSSSSNVAVH 312
N + ++W++ L +S + ++ RQ H G L GGAQ S SS ++
Sbjct: 37 NPKPSSWRKKILPESFFKEPDSGSHSRQSSTDSSGGHPGPRLA-GGAQHVRSHSSPASLQ 95
Query: 313 TGTGSQTPAVNXXXXXXXXXXXXXXXXLGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDP 372
GTG+ LPPGWE FT G+ YF++H + TTW DP
Sbjct: 96 LGTGAGAAGSPAQQHAHLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
Query: 373 RR 374
R+
Sbjct: 156 RK 157
>Hs17433806_2 [R] KOG3209 WW domain-containing protein
Length = 949
Score = 59.3 bits (142), Expect = 2e-08
Identities = 24/35 (68%), Positives = 27/35 (76%)
Query: 396 LGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRL 430
L PLP WEM T+T +YF+DHNTKTTTW DPRL
Sbjct: 91 LEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRL 125
Score = 55.5 bits (132), Expect = 3e-07
Identities = 30/78 (38%), Positives = 38/78 (48%), Gaps = 10/78 (12%)
Query: 340 LGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPL 399
L LP WE +T G YF+DHNT+TTTW+DPR + + P + G L
Sbjct: 91 LEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRLCK--KAKAPED--------CEDGEL 140
Query: 400 PSGWEMRLTNTARVYFVD 417
P GWE Y+VD
Sbjct: 141 PYGWEKIEDPQYGTYYVD 158
>Hs11141889_2 [R] KOG1891 Proline binding protein WW45
Length = 204
Score = 59.3 bits (142), Expect = 2e-08
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 26/99 (26%)
Query: 343 LPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSG 402
LPPGW +T GR Y++DHNT TT W P ++ LP G
Sbjct: 22 LPPGWSVDWTMRGRKYYIDHNTNTTHWSHPLERE---------------------GLPPG 60
Query: 403 WEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQY 441
WE ++ Y+VDH K + P PS VP+Y
Sbjct: 61 WERVESSEFGTYYVDHTNKKAQYRHPCAPS-----VPRY 94
>Hs7661612 [O] KOG0941 E3 ubiquitin protein ligase
Length = 110
Score = 55.1 bits (131), Expect = 4e-07
Identities = 26/63 (41%), Positives = 39/63 (61%)
Query: 469 VRRKNIFEDSYQEIMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCL 528
VRR+NI D+ + + + D KK L + F GE+ +D GGV +EFF L+ E+ +P Y +
Sbjct: 30 VRRENIVGDAMEVLRKAKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGM 89
Query: 529 FEY 531
F Y
Sbjct: 90 FRY 92
>CE03201 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 457
Score = 54.3 bits (129), Expect = 7e-07
Identities = 29/71 (40%), Positives = 38/71 (52%), Gaps = 11/71 (15%)
Query: 360 VDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHN 419
+ N + +DP R+ ++ Q V QL P+P GWEM + YF DHN
Sbjct: 192 MQQNREKSLSLDPMRRPFMTP----------QDVEQL-PMPQGWEMCYDSDGVRYFKDHN 240
Query: 420 TKTTTWDDPRL 430
+KTTTWDDPRL
Sbjct: 241 SKTTTWDDPRL 251
>7297326 [Q] KOG1208 Dehydrogenases with different specificities (related to
short-chain alcohol dehydrogenases)
Length = 409
Score = 53.9 bits (128), Expect = 1e-06
Identities = 35/108 (32%), Positives = 50/108 (45%), Gaps = 19/108 (17%)
Query: 342 ELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
ELPPGWE+R T +G +V+ +T+ W PR + R G LP
Sbjct: 12 ELPPGWEERATDDGTVCYVNQQGKTSQWTHPRTGRSKRI---------------TGELPL 56
Query: 402 GWEMRLTNTA-RVYFVDHNTKTTTWDDPRLPSSLD---QNVPQYKRDF 445
GWE R F++ T+ T DPRL +++ QNV Q ++ F
Sbjct: 57 GWEKYYDEQGKRFMFLNKETQQRTNVDPRLAFAVEEPTQNVAQVRQRF 104
>7291734 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 314
Score = 53.9 bits (128), Expect = 1e-06
Identities = 21/49 (42%), Positives = 31/49 (62%)
Query: 395 QLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKR 443
QLG LP GWE TN ++Y+++H TK+T W+DPR+ Q + +R
Sbjct: 239 QLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAER 287
Score = 52.4 bits (124), Expect = 3e-06
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 6/64 (9%)
Query: 340 LGELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPL 399
LG LPPGWEQ T +G+ Y+++H T++T W DPR Q Y + + + Q G
Sbjct: 240 LGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQ-----YRQQQQILMAERIKQNGS- 293
Query: 400 PSGW 403
+GW
Sbjct: 294 TAGW 297
Score = 50.8 bits (120), Expect = 8e-06
Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 237 QYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQSEVQRVNTELERRQHRGRTLPD 296
Q G LPPGWE+ N G+ YY++H T++T W+ P + + Q++ ER + G T
Sbjct: 239 QLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQI-LMAERIKQNGSTAGW 297
Query: 297 GGAQS 301
GA S
Sbjct: 298 LGAGS 302
>At3g59770 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 1616
Score = 53.5 bits (127), Expect = 1e-06
Identities = 21/35 (60%), Positives = 27/35 (77%), Gaps = 1/35 (2%)
Query: 241 LPPGWERRTDNF-GRTYYVDHNTRTTTWKRPTLDQ 274
LPPGWE+R D G++YY+DHNT+TTTW P D+
Sbjct: 510 LPPGWEKRADAVTGKSYYIDHNTKTTTWSHPCPDK 544
>Hs14043024_1 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 106
Score = 53.5 bits (127), Expect = 1e-06
Identities = 22/43 (51%), Positives = 31/43 (71%), Gaps = 1/43 (2%)
Query: 398 PLPSGWEMRLT-NTARVYFVDHNTKTTTWDDPRLPSSLDQNVP 439
PLP GWE+++ T +FVDHN++TTTW+DPR+PS + P
Sbjct: 21 PLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPSEGPKETP 63
Score = 51.2 bits (121), Expect = 6e-06
Identities = 28/61 (45%), Positives = 36/61 (58%), Gaps = 10/61 (16%)
Query: 343 LPPGWEQRFTPE-GRAYFVDHNTRTTTWVDPRRQQYIRTYGPSTNTIQQQPVSQLGPLPS 401
LPPGWE + P+ G +FVDHN+RTTTW DPR + + GP ++ P S GP
Sbjct: 22 LPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPR----VPSEGP-----KETPSSANGPSRE 72
Query: 402 G 402
G
Sbjct: 73 G 73
>CE06034 [R] KOG3209 WW domain-containing protein
Length = 1012
Score = 52.8 bits (125), Expect = 2e-06
Identities = 21/33 (63%), Positives = 23/33 (69%)
Query: 341 GELPPGWEQRFTPEGRAYFVDHNTRTTTWVDPR 373
G LPP WE +T G YF+DHNT TTTW DPR
Sbjct: 131 GLLPPNWETAYTENGDKYFIDHNTGTTTWDDPR 163
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,679,103
Number of Sequences: 60738
Number of extensions: 1967685
Number of successful extensions: 5838
Number of sequences better than 1.0e-05: 90
Number of HSP's better than 0.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 5220
Number of HSP's gapped (non-prelim): 275
length of query: 819
length of database: 30,389,216
effective HSP length: 115
effective length of query: 704
effective length of database: 23,404,346
effective search space: 16476659584
effective search space used: 16476659584
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)