ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3612 good Z KOG2026 Cytoskeleton Spindle pole body protein - Sad1p
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3612 1250334 1251764 477
(477 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR005c [Z] KOG2026 Spindle pole body protein - Sad1p 277 2e-74
SPBC577.07 [Z] KOG2026 Spindle pole body protein - Sad1p 249 8e-66
7293523 [Z] KOG2026 Spindle pole body protein - Sad1p 244 2e-64
CE20660 [Z] KOG2026 Spindle pole body protein - Sad1p 243 6e-64
At4g22410 [Z] KOG2026 Spindle pole body protein - Sad1p 187 3e-47
At4g22290_2 [Z] KOG2026 Spindle pole body protein - Sad1p 173 4e-43
Hs14732941 [Z] KOG2026 Spindle pole body protein - Sad1p 138 2e-32
At4g22350 [Z] KOG2026 Spindle pole body protein - Sad1p 109 8e-24
Hs5730025 [Z] KOG2026 Spindle pole body protein - Sad1p 103 4e-22
>YFR005c [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 448
Score = 277 bits (709), Expect = 2e-74
Identities = 166/446 (37%), Positives = 248/446 (55%), Gaps = 39/446 (8%)
Query: 40 YLDQIDMKKLDFDREKVCSVTLSRSNVYCCLSSGKYLQGRGQNSVAFKHAIESDHHVFLN 99
YL+ + +KLDFD EK+C +TLS NVYCCL G Y QGR + S AF H+I+ +HHVFLN
Sbjct: 31 YLETVVREKLDFDSEKICCITLSPLNVYCCLVCGHYYQGRHEKSPAFIHSIDENHHVFLN 90
Query: 100 LKSLKVYVLPEN----YEADVVPGSLLSDIVYAASPRFHNSQLQTFPKVCHDLNDKRYLN 155
L SLK Y+LP+N ++ +V LL+ I +AA P + L+ FP+ C DL+++ YLN
Sbjct: 91 LTSLKFYMLPQNVQILHDGEV---QLLNSIKFAAYPTYCPKDLEDFPRQCFDLSNRTYLN 147
Query: 156 GFVGMNNLTPDGYSVVVLQALAHVLPIRDYFLLGESSSGYNTDENDGPXXXXXXXXXXRK 215
GF+G N Y+ VL ++H++P+RD+FLL N +N G +K
Sbjct: 148 GFIGFTNAATYDYAHSVLLLISHMVPVRDHFLL-------NHFDNQG-EFIKRLSICVKK 199
Query: 216 LWSCKLLRRNISPHELLNYISLVSKRRFPVDDSRDPRSFLLWLISSLCASKEPSLVRTVT 275
+WS KL + ++S + ++Y+ + + DPR FLLWL + +C+S L +
Sbjct: 200 IWSPKLFKHHLSVDDFVSYLKVREGLNL---NPIDPRLFLLWLFNKICSSSN-DLKSILN 255
Query: 276 DQFQGHVEITSTPIETVVDEKGKTMKFKKLEAATTTQKTK-FWLLSLDLPQMNLFSNGNS 334
+G V+I V+ K + E+ T K FW+L+LDLP+ + F +GNS
Sbjct: 256 HSCKGKVKIAK------VENKPEAS-----ESVTGKVIVKPFWVLTLDLPEFSPFEDGNS 304
Query: 335 ANSVSQTKLETLLQKFNGETEYHTKDSIKTYRILKHPKFLILHFNRFDKGFT-SIKDRNK 393
+ + Q + LL KF T+ + + + + + P+FLI HFNRFD+ +K+RN+
Sbjct: 305 VDDLPQINITKLLTKF---TKSRSSSTSTVFELTRLPQFLIFHFNRFDRNSDHPVKNRNQ 361
Query: 394 TLVEFSEKLEFSGVHYKLLVNITHDCVIQMKISDTEDLLA---SRWKVHLADTLRDQWYE 450
TLVEFS +LE V Y+L N+ H VI+ +D S W L D ++W E
Sbjct: 362 TLVEFSSELEILHVKYRLKANVVH-VVIKQPSTDGNAFNGDEKSHWITQLYDNKSEKWIE 420
Query: 451 FDDIEVNKVEKEFLFLKECYIQIWQR 476
D I + E E LFLKE +IQ+W++
Sbjct: 421 IDGINTTEREAELLFLKETFIQVWEK 446
>SPBC577.07 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 502
Score = 249 bits (635), Expect = 8e-66
Identities = 154/484 (31%), Positives = 250/484 (50%), Gaps = 48/484 (9%)
Query: 21 DSNKVGKIDVQQKRSVP----KVYLDQIDMKKLDFDREKVCSVTLSRSNVYCCLSSGKYL 76
D + + ++++ + P +YLD I+ K LDFD EKVCSV+L+ +VY CL G+Y
Sbjct: 37 DVHDIASKEMEEHETTPIISQNLYLDTINRKLLDFDFEKVCSVSLTNLSVYACLVCGRYF 96
Query: 77 QGRGQNSVAFKHAIESDHHVFLNLKSLKVYVLPENYEADVVPGSLLSDIVYAASPRFHNS 136
QGRG +S A+ HA+ +HHVF+N +LK YVLPE+Y+ V S L DI Y P F
Sbjct: 97 QGRGPSSHAYFHALTENHHVFVNCSTLKFYVLPESYQ---VESSALQDIAYVMRPTFTKL 153
Query: 137 QLQTF---PKVCHDLNDKRYLNGFVGMNNLTPDGYSVVVLQALAHVLPIRDYFLLGESSS 193
++Q P++ +DL K Y+ GFVGMNN+ + Y VV+ LAHV P R+YFLL
Sbjct: 154 EVQRLDHTPQLSYDLMLKPYVPGFVGMNNIKNNDYFNVVIHMLAHVKPFRNYFLL----- 208
Query: 194 GYNTDENDGPXXXXXXXXXXRKLWSCKLLRRNISPHELLNYISLVSKRRFPVDDSRDPRS 253
+ ++ P RKLW+ K + ++SP EL+ ++++S +++ +++ +DP
Sbjct: 209 ---KNFDNCPQLVQRLAILIRKLWNHKAFKSHVSPQELIQEVTVLSHKKYSINEQKDPVE 265
Query: 254 FLLWLISSL--CASKEPSLVRTVTD----QFQGHVEITSTPIETVVDEKGKTMKFKKLEA 307
FL W +++L C + S + T FQG V I S I EKG+ + F +
Sbjct: 266 FLSWFLNTLHNCLGGKKSTIAKPTSIVHYSFQGFVRIESQKIRQHA-EKGEQVVFTG-DR 323
Query: 308 ATTTQKTKFWLLSLDLPQMNLFSNGNSANSVSQTKLETLLQKFNGETEYHTKDSIKTYRI 367
T F L+LDLP +F + N + Q +L+ +L K+NG + + +
Sbjct: 324 VIQTNVVPFLYLTLDLPPKPIFQDEFEGNIIPQVELKEILNKYNGVHTQELAGMRRRFHL 383
Query: 368 LKHPKFLILHFNRFDKGFTSIKDRNKTLVEFS-EKLEFS--------------GVHYKLL 412
+ P + I H RF K +RN+T+V F + + S Y L+
Sbjct: 384 MTAPPYFIFHIKRFMKN-NYFTERNQTIVTFPLDDFDMSPFIDDSFIQSNPKISTKYNLV 442
Query: 413 VNITHDCVIQMKISDTEDLLASRWKVHLADTLRDQWYEFDDIEVNKVEKEFLFLKECYIQ 472
NI H+ V + E+ +++ + + ++WY+ D+ V ++ + + L E +IQ
Sbjct: 443 ANIIHESVTHAE----EEF--HNFRIQIRNPSTNKWYQIQDLYVEEISSDMIRLGESFIQ 496
Query: 473 IWQR 476
+W+R
Sbjct: 497 LWER 500
>7293523 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 719
Score = 244 bits (624), Expect = 2e-64
Identities = 160/465 (34%), Positives = 237/465 (50%), Gaps = 43/465 (9%)
Query: 40 YLDQIDMKKLDFDREKVCSVTLSRSNVYCCLSSGKYLQGRGQNSVAFKHAIESDHHVFLN 99
YLD I+ LDFD EK+CS++L+R NVY CL GKY QGRG N+ A+ H++ HHVFLN
Sbjct: 29 YLDTINRNLLDFDFEKLCSISLTRINVYACLVCGKYFQGRGTNTHAYTHSVGEAHHVFLN 88
Query: 100 LKSLKVYVLPENYEADVVPGSLLSDIVYAASPRFHNSQL----QTFPKVCHDLNDKRYLN 155
L +L+ Y LP+NYE + S L DI Y +P F ++ Q PK ++ YL
Sbjct: 89 LHTLRFYCLPDNYE---IIDSSLDDIKYVLNPTFTRQEISKLDQLQPKHSRTVDGVLYLP 145
Query: 156 GFVGMNNLTPDGYSVVVLQALAHVLPIRDYFLLGESSSGYNTDENDGP-XXXXXXXXXXR 214
G VG+NN+ + Y VVL AL+HV P+RDYFL +S + D R
Sbjct: 146 GVVGLNNIKANDYCNVVLHALSHVGPLRDYFLQKQSYAHVVRPPGDSVFTLVQRFGELMR 205
Query: 215 KLWSCKLLRRNISPHELLNYISLVSKRRFPVDDSRDPRSFLLWLIS----SLCASKEPSL 270
K+W+ + + ++SPHE+L + L S +RF + + DP FL W ++ +L +K P+
Sbjct: 206 KMWNPRNFKSHVSPHEMLQAVVLWSSKRFQITEQGDPIDFLSWFLNTLHRALKGNKHPN- 264
Query: 271 VRTVTDQFQGHVEITSTPIETV-VDEKGKTMKFKKLEAATTTQKTKFWLLSLDLPQMNLF 329
+ F G ++I + + V +D+ K E + F L+ DLP LF
Sbjct: 265 SSILYKIFLGEMKIYTRKMPPVELDDAAKAQLLATEEYKDQVEDKNFIYLTCDLPPPPLF 324
Query: 330 SNGNSANSVSQTKLETLLQKFNG--ETEYHT--KDSIKTYRILKHPKFLILHFNRFDKGF 385
++ N + Q L LL KFNG E EY T + +K + I + P+F+IL+ RF K
Sbjct: 325 TDEFRENIIPQVNLYQLLSKFNGTAEKEYKTYKANFMKRFEITRLPQFIILYIKRFTKN- 383
Query: 386 TSIKDRNKTLVEFSEK-LEFSGV-------------HYKLLVNITHDCVIQMKISDTEDL 431
T ++N T+V F K ++F + Y L+ NI HD D
Sbjct: 384 TFFLEKNPTIVNFPIKHVDFGDILGMRQRDKDVKDTKYNLVANIVHD----------GDP 433
Query: 432 LASRWKVHLADTLRDQWYEFDDIEVNKVEKEFLFLKECYIQIWQR 476
++ H+ QWYE D+ V ++ + + L E YIQI++R
Sbjct: 434 KKGTYRAHILHKANGQWYEMQDLHVTEILPQMITLTESYIQIYER 478
>CE20660 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 602
Score = 243 bits (619), Expect = 6e-64
Identities = 158/501 (31%), Positives = 252/501 (49%), Gaps = 47/501 (9%)
Query: 5 KREFGEIIDSDGDVDHDSNKVGKIDVQQ--KRSVPKVYLDQIDMKKLDFDREKVCSVTLS 62
+R E + S +HD + V + Q K+S YLD ID LDFD EK CSV+LS
Sbjct: 101 QRIIEEELKSGKHDEHDDDPVWSMKKAQAEKKSRMCPYLDTIDRSVLDFDFEKQCSVSLS 160
Query: 63 RSNVYCCLSSGKYLQGRGQNSVAFKHAIESDHHVFLNLKSLKVYVLPENYEADVVPGSLL 122
NVY C+ GKY QGRG N+ A+ HA+E+DHHVFLNL++LK Y LP+NYE V L
Sbjct: 161 HQNVYACMVCGKYFQGRGTNTHAYTHALETDHHVFLNLQTLKFYCLPDNYE---VIDPSL 217
Query: 123 SDIVYAASPRFHNSQLQTF---PKVCHDLNDKRYLNGFVGMNNLTPDGYSVVVLQALAHV 179
DI Y P + + + K+ +D Y G VG+NN+ + Y +LQAL+ V
Sbjct: 218 EDIKYVLKPTYTKEMIASIDKQSKMVRAYDDSTYFPGVVGLNNIKANDYCNAILQALSAV 277
Query: 180 LPIRDYFLLGESSSGYNTDENDG-PXXXXXXXXXXRKLWSCKLLRRNISPHELLNYISLV 238
P+R++FL + + D RKLW+ + LR ++SPHE+L + +
Sbjct: 278 RPLRNWFLKESNYTSIKRPPGDKLTLLPQRFGELIRKLWNPRALRTHVSPHEMLQAVVVC 337
Query: 239 SKRRFPVDDSRDPRSFLLWLISSLCAS-----KEPSLVRTVTDQFQGHVEITSTPIETVV 293
S ++F D F+L+L+++L ++ K+PS+ ++ F+G + S +
Sbjct: 338 SNKKFQFIKQNDAADFMLFLLTTLHSALNGTDKKPSI---ISKTFRGRMRQYSRRVIPAE 394
Query: 294 D-EKGKTMKFKKLEAATTTQKTKFWLLSLDLPQMNLFSNGNSANSVSQTKLETLLQKFNG 352
D ++ K MK + E ++ F L+LDLP L+ + N + Q L TLL+KF+G
Sbjct: 395 DTDEEKYMKLRMPEYQEKVIESPFLYLTLDLPSAPLYRDVQLQNIIPQVPLSTLLEKFDG 454
Query: 353 ETE-----YHTKDSIKTYRILKHPKFLILHFNRFDKGFTSIKDRNKTLVEF--------- 398
+TE Y+ + +K + +L+ P FLI+ + RF K + ++N T+V F
Sbjct: 455 KTEKEYPTYNDNNIMKRFELLQLPDFLIITYKRFQKNQWFV-EKNPTIVNFPIANVDFYD 513
Query: 399 ----SEKLEFSGVHYKLLVNITHDCVIQMKISDTEDLLASRWKVHLADTLRDQWYEFDDI 454
+ Y L+ N+ H+ + +++ + +W+E +D+
Sbjct: 514 CLAKDARANHKYTTYDLVANVVHEGTFK----------DGNYRIQIVHEGSGKWFELEDL 563
Query: 455 EVNKVEKEFLFLKECYIQIWQ 475
V + + + L E YIQIW+
Sbjct: 564 HVKDLLPQMIVLAESYIQIWR 584
>At4g22410 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 340
Score = 187 bits (475), Expect = 3e-47
Identities = 124/364 (34%), Positives = 185/364 (50%), Gaps = 37/364 (10%)
Query: 44 IDMKKLDFDREKVCSVTLSRSNVYCCLSSGKYLQGRGQNSVAFKHAIESDHHVFLNLKSL 103
++ + LDF E+ CSV+LS NVY CL GKY QGR Q S A+ H++E+ HHV++NL +
Sbjct: 2 VEFQVLDFHFERFCSVSLSNLNVYACLVCGKYFQGRSQKSHAYTHSLEAGHHVYINLLTE 61
Query: 104 KVYVLPENYEADVVPGSLLSDIVYAASPRFHNSQLQTFPK---VCHDLNDKRYLNGFVGM 160
KVY LP++YE + L DI + +PRF +Q+ K L+ YL G VG+
Sbjct: 62 KVYCLPDSYE---INDPSLDDIRHVLNPRFSRAQVNELDKNRQWSRALDGSDYLPGMVGL 118
Query: 161 NNLTPDGYSVVVLQALAHVLPIRDYFLLGESSSGYNTDENDGPXXXXXXXXXXRKLWSCK 220
NN+ + V +Q+L V P+R++F + E N P RK+W +
Sbjct: 119 NNIQKTEFVNVTIQSLMRVTPLRNFFHIPE-----NYQHCKSP-LVHCFGELTRKIWHAR 172
Query: 221 LLRRNISPHELLNYISLVSKRRFPVDDSRDPRSFLLWLISS----LCASKEPSLVRTVTD 276
+ +SPHE L + SK+RF + DP F+ WL+++ L SK+ S + +
Sbjct: 173 NFKGQVSPHEFLQAVMKASKKRFRIGQQSDPVEFMSWLLNTLHMDLRTSKDASSI--IHK 230
Query: 277 QFQGHVEITSTPIETVVDEKGKTMKFKKLEAATTTQKTKFWLLSLDLPQMNLFSNGNSAN 336
FQG +E+ V + +G K + F +L LDLP LF + N
Sbjct: 231 CFQGELEV-------VKEFQGNENK--------EISRMSFLMLGLDLPPPPLFKDVMEKN 275
Query: 337 SVSQTKLETLLQKFNGET---EYHTKDSIKTYRILKHPKFLILHFNRFDKGFTSIKDRNK 393
+ Q L LL+KF+GET K + YR++K P++L+ H RF K K++N
Sbjct: 276 IIPQVALFDLLKKFDGETVTEVVRPKLARMRYRVIKSPRYLMFHMVRFKKN-NFFKEKNP 334
Query: 394 TLVE 397
TL E
Sbjct: 335 TLGE 338
>At4g22290_2 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 543
Score = 173 bits (439), Expect = 4e-43
Identities = 151/516 (29%), Positives = 227/516 (43%), Gaps = 96/516 (18%)
Query: 4 VKREFGEIIDSDGDVDHDSNKVGKID--VQQKRSVPKVYLDQIDMKKLDFDREKVCSVTL 61
VK E E +D D D D K GK V+ +R P YLD ++ + LDFD E+ CSV+L
Sbjct: 78 VKGEAQEEVDDDEDDDVSKGK-GKHSRHVEVRRDCP--YLDTVNRQVLDFDFERFCSVSL 134
Query: 62 SRSNVYCCLSSGKYLQGRGQNSVAFKHAIESDHHVFLNLKSLKVYVLPENYEADVVPGSL 121
S NVY CL GKY QGR Q S A+ H++E+ HHV++NL + KVY LP++YE +
Sbjct: 135 SNLNVYACLVCGKYFQGRSQKSHAYTHSLEAGHHVYINLLTEKVYCLPDSYE---INDPS 191
Query: 122 LSDIVYAASPRFHNSQLQTF-------PKVCHDLNDKRYLNGFVGMNNLTPDGYSVVVLQ 174
L DI + +PR+ S F +C L L+ V + ++LQ
Sbjct: 192 LDDIRHVLNPRYIRSCDYYFIVLTAFCVLICEHLEHITLLSCLVKFS---------LILQ 242
Query: 175 ALAHVLPIRDYFLLGESSSGYNTDENDGPXXXXXXXXXXRKLWSCKLLRRNISPHELLNY 234
L + + + D+N R L L +SPHE L
Sbjct: 243 FLFMKASVLSIYRFSRAQVN-ELDKN---------RQWSRALDGSDYLPGMVSPHEFLQA 292
Query: 235 ISLVSKRRFPVDDSRDPRSFLLWLISS----LCASKEPSLVRTVTDQFQGHVEITSTPIE 290
+ SK+RF + DP F+ WL+++ L SK+ S + + FQG +E+
Sbjct: 293 VMKASKKRFRIGQQSDPVEFMSWLLNTLHMDLRTSKDASSI--IHKCFQGELEV------ 344
Query: 291 TVVDEKGKTMKFKKLEAATTTQKTKFWLLSLDLPQMNLFSNGNSANSVSQTKLETLLQKF 350
V + +G K + F +L LDLP LF + N + Q L LL+KF
Sbjct: 345 -VKEFQGNENK--------EISRMSFLMLGLDLPPPPLFKDVMEKNIIPQVALFDLLKKF 395
Query: 351 NGET---EYHTKDSIKTYRILKHPKFLILHFNRFDKGFTSIKDRNKTLVEFSEKLEFSGV 407
+GET K + YR++K P++L+ H RF K K++N TL ++ V
Sbjct: 396 DGETVTEVVRPKLARMRYRVIKSPRYLMFHMVRFKKN-NFFKEKNPTLGSLMPIFSYATV 454
Query: 408 H---------------------------YKLLVNITHDCVIQMKISDTEDLLASRWKVHL 440
+ Y L+ NI HD ED ++V +
Sbjct: 455 NFPVKDMELRDYIPSLPRAPEGENVCSKYNLIANIVHD-------GKPED---GYFRVFV 504
Query: 441 ADTLRDQWYEFDDIEVNKVEKEFLFLKECYIQIWQR 476
++ WYE D+ V + + + L E Y+QI+++
Sbjct: 505 QRKSQELWYEMQDLHVAETLPQMVELSEAYMQIYEQ 540
>Hs14732941 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 404
Score = 138 bits (347), Expect = 2e-32
Identities = 109/371 (29%), Positives = 170/371 (45%), Gaps = 36/371 (9%)
Query: 131 PRFHNSQLQTFPK---VCHDLNDKRYLNGFVGMNNLTPDGYSVVVLQALAHVLPIRDYFL 187
P F Q+ K + + YL G VG+NN+ + Y+ VLQAL++V P+R+YFL
Sbjct: 34 PTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFL 93
Query: 188 LGESSSGYNTDENDGPXXXXXXXXXX-RKLWSCKLLRRNISPHELLNYISLVSKRRFPVD 246
++ D RKLW+ + + ++SPHE+L + L SK+ F +
Sbjct: 94 EEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQIT 153
Query: 247 DSRDPRSFLLWLISSL---CASKEPSLVRTVTDQFQGHVEITSTPI-ETVVDEKGKTMKF 302
D FL W +++L + VTD FQG + I + + + + K
Sbjct: 154 KQGDGVDFLSWFLNALHSALGGTKKKKKTIVTDVFQGSMRIFTKKLPHPDLPAEEKEQLL 213
Query: 303 KKLEAATTTQKTKFWLLSLDLPQMNLFSNGNSANSVSQTKLETLLQKFNG--ETEYHT-- 358
E T ++ F L+LDLP L+ + + Q L +L KFNG E EY T
Sbjct: 214 HNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYK 273
Query: 359 KDSIKTYRILKHPKFLILHFNRFDKGFTSIKDRNKTLVEF-------SEKL--EFSGVH- 408
++ +K +++ K P +LI RF K ++N T+V F E L E VH
Sbjct: 274 ENFLKRFQLTKLPPYLIFCIKRFTKN-NFFVEKNPTIVNFPITNVDLREYLSEEVQAVHK 332
Query: 409 ---YKLLVNITHDCVIQMKISDTEDLLASRWKVHLADTLRDQWYEFDDIEVNKVEKEFLF 465
Y L+ NI HD K S+ +++H+ +WYE D++V + + +
Sbjct: 333 NTTYDLIANIVHD----GKPSE------GSYRIHVLHHGTGKWYELQDLQVTDILPQMIT 382
Query: 466 LKECYIQIWQR 476
L E YIQIW+R
Sbjct: 383 LSEAYIQIWKR 393
>At4g22350 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 477
Score = 109 bits (273), Expect = 8e-24
Identities = 68/161 (42%), Positives = 93/161 (57%), Gaps = 11/161 (6%)
Query: 4 VKREFGEIIDSDGDVDHDSNKV-GKID--VQQKRSVPKVYLDQIDMKKLDFDREKVCSVT 60
VK E +D D D D D++K GK V+ +R P YLD ++ + LDFD E+ CSV+
Sbjct: 74 VKGEAQVEVDDDEDDDDDASKGRGKHSRHVEVRRDCP--YLDTVNRQVLDFDFERFCSVS 131
Query: 61 LSRSNVYCCLSSGKYLQGRGQNSVAFKHAIESDHHVFLNLKSLKVYVLPENYEADVVPGS 120
LS NVY CL GKY QGR Q S A+ H++E+ HHV++NL + KVY LP++YE +
Sbjct: 132 LSNLNVYACLVCGKYFQGRSQKSHAYTHSLEAGHHVYINLLTEKVYCLPDSYE---INDP 188
Query: 121 LLSDIVYAASPRFHNSQLQTFPK---VCHDLNDKRYLNGFV 158
L DI + +PRF +Q+ K L+ YL G V
Sbjct: 189 SLDDIRHVLNPRFSRAQVNELDKNRQWSRALDGSDYLPGMV 229
Score = 98.6 bits (244), Expect = 2e-20
Identities = 80/274 (29%), Positives = 124/274 (45%), Gaps = 51/274 (18%)
Query: 226 ISPHELLNYISLVSKRRFPVDDSRDPRSFLLWLISS----LCASKEPSLVRTVTDQFQGH 281
+SPHE L + SK+RF + DP F+ WL+++ L SK+ S + + FQG
Sbjct: 229 VSPHEFLQAVMKASKKRFRIGQQSDPVEFMSWLLNTLHMDLRTSKDASSI--IHKCFQGE 286
Query: 282 VEITSTPIETVVDEKGKTMKFKKLEAATTTQKTKFWLLSLDLPQMNLFSNGNSANSVSQT 341
+E+ V + +G K + F +L LDLP LF + N + Q
Sbjct: 287 LEV-------VKEYQGNENK--------EISRMPFLMLGLDLPPPPLFKDVMEKNIIPQV 331
Query: 342 KLETLLQKFNGET---EYHTKDSIKTYRILKHPKFLILHFNRFDKGFTSIKDRNKTLVEF 398
L LL+KF+GET K + YR++K P++L+ H RF K K++N TLV F
Sbjct: 332 ALFDLLKKFDGETVTEVVRPKLARMRYRVIKSPRYLMFHMVRFKKN-NFFKEKNPTLVNF 390
Query: 399 SEK-LEFSGV---------------HYKLLVNITHDCVIQMKISDTEDLLASRWKVHLAD 442
K +E Y L+ NI HD ED ++V +
Sbjct: 391 PVKDMELRDYIPSLPRAPEGENVCSKYNLIANIVHD-------GKPED---GYFRVFVQR 440
Query: 443 TLRDQWYEFDDIEVNKVEKEFLFLKECYIQIWQR 476
++ WYE D+ V + + + L E Y+QI+++
Sbjct: 441 KSQELWYEMQDLHVAETLPQMVELSEAYMQIYEQ 474
>Hs5730025 [Z] KOG2026 Spindle pole body protein - Sad1p
Length = 324
Score = 103 bits (258), Expect = 4e-22
Identities = 80/280 (28%), Positives = 128/280 (45%), Gaps = 13/280 (4%)
Query: 131 PRFHNSQLQTFPK---VCHDLNDKRYLNGFVGMNNLTPDGYSVVVLQALAHVLPIRDYFL 187
P F Q+ K + + YL G VG+NN+ + Y+ VLQAL++V P+R+YFL
Sbjct: 34 PTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFL 93
Query: 188 LGESSSGYNTDENDGPXXXXXXXXXX-RKLWSCKLLRRNISPHELLNYISLVSKRRFPVD 246
++ D RKLW+ + + ++SPHE+L + L SK+ F +
Sbjct: 94 EEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQIT 153
Query: 247 DSRDPRSFLLWLISSL---CASKEPSLVRTVTDQFQGHVEITSTPI-ETVVDEKGKTMKF 302
D FL W +++L + VTD FQG + I + + + + K
Sbjct: 154 KQGDGVDFLSWFLNALHSALGGTKKKKKTIVTDVFQGSMRIFTKKLPHPDLPAEEKEQLL 213
Query: 303 KKLEAATTTQKTKFWLLSLDLPQMNLFSNGNSANSVSQTKLETLLQKFNG--ETEYHT-- 358
E T ++ F L+LDLP L+ + + Q L +L KFNG E EY T
Sbjct: 214 HNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYK 273
Query: 359 KDSIKTYRILKHPKFLILHFNRFDKGFTSIKDRNKTLVEF 398
++ +K +++ K P +LI F K ++N T +F
Sbjct: 274 ENFLKRFQLTKLPPYLIFCIKIFTKN-NFFVEKNPTSCQF 312
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,190,216
Number of Sequences: 60738
Number of extensions: 1273297
Number of successful extensions: 3168
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3121
Number of HSP's gapped (non-prelim): 11
length of query: 477
length of database: 30,389,216
effective HSP length: 110
effective length of query: 367
effective length of database: 23,708,036
effective search space: 8700849212
effective search space used: 8700849212
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)