ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3617 good O KOG1555 Posttranslational modification, protein turnover, chaperones 26S proteasome regulatory complex, subunit RPN11
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3617 1252815 1251883 -311
(311 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR004w [O] KOG1555 26S proteasome regulatory complex subunit RPN11 495 e-140
SPAC31G5.13 [O] KOG1555 26S proteasome regulatory complex subuni... 403 e-112
Hs5031981 [O] KOG1555 26S proteasome regulatory complex subunit ... 388 e-108
7296942 [O] KOG1555 26S proteasome regulatory complex subunit RPN11 388 e-108
CE19527 [O] KOG1555 26S proteasome regulatory complex subunit RPN11 377 e-104
At5g23540 [O] KOG1555 26S proteasome regulatory complex subunit ... 377 e-104
ECU11g0570 [O] KOG1555 26S proteasome regulatory complex subunit... 313 2e-85
CE00707 [O] KOG1555 26S proteasome regulatory complex subunit RPN11 295 6e-80
7300154 [OT] KOG1554 COP9 signalosome subunit CSN5 144 2e-34
Hs5803046 [OT] KOG1554 COP9 signalosome subunit CSN5 135 6e-32
At1g71230 [OT] KOG1554 COP9 signalosome subunit CSN5 135 6e-32
At1g22920 [OT] KOG1554 COP9 signalosome subunit CSN5 134 2e-31
CE06722 [OT] KOG1554 COP9 signalosome subunit CSN5 122 9e-28
SPAC1687.13c [OT] KOG1554 COP9 signalosome subunit CSN5 119 7e-27
Hs17463759 [OT] KOG1554 COP9 signalosome subunit CSN5 105 1e-22
YDL216c [OT] KOG1554 COP9 signalosome subunit CSN5 86 9e-17
Hs4503515 [J] KOG1560 Translation initiation factor 3 subunit h ... 61 2e-09
Hs13236583 [O] KOG1555 26S proteasome regulatory complex subunit... 59 1e-08
At1g10840 [J] KOG1560 Translation initiation factor 3 subunit h ... 58 2e-08
At1g10600 [T] KOG2880 SMAD6 interacting protein AMSH contains JA... 56 6e-08
SPAC19B12.10 [T] KOG2880 SMAD6 interacting protein AMSH contains... 52 1e-06
At1g48790 [T] KOG2880 SMAD6 interacting protein AMSH contains JA... 52 1e-06
Hs16158201_2 [O] KOG1555 26S proteasome regulatory complex subun... 50 4e-06
>YFR004w [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 306
Score = 495 bits (1275), Expect = e-140
Identities = 248/311 (79%), Positives = 272/311 (86%), Gaps = 5/311 (1%)
Query: 1 MESLQRMMMSQRAGMMGANATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLG 60
ME LQR+MM+ + G + + DDTKETVYISS+ALLKMLKHGRAGVPMEVMGLMLG
Sbjct: 1 MERLQRLMMNSKVG-----SADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLG 55
Query: 61 EFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFG 120
EFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFG
Sbjct: 56 EFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFG 115
Query: 121 CWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQNTS 180
CWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLID ++ N EPRQ TS
Sbjct: 116 CWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTS 175
Query: 181 NIGLINKPNIQALIHGLNRHYYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREE 240
N GL+NK NIQALIHGLNRHYYSLNIDYHKT+ E MLMNLHKEQWQSGLKM+D++E+EE
Sbjct: 176 NTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEE 235
Query: 241 HNLGETQKMIKIAEQFTKRIXXXXXXXXXXXKTRYVGKQDPKRHLAETAEKLLEDNIVSV 300
NL T+ M+KIAEQ++KRI KTRYVG+QDPK+HL+ETA++ LE+NIVSV
Sbjct: 236 SNLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSV 295
Query: 301 LTAGVNSVAIK 311
LTAGVNSVAIK
Sbjct: 296 LTAGVNSVAIK 306
>SPAC31G5.13 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 308
Score = 403 bits (1035), Expect = e-112
Identities = 206/311 (66%), Positives = 238/311 (76%), Gaps = 6/311 (1%)
Query: 1 MESLQRMMMSQR--AGMMGANATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLM 58
MESLQR++ R GMMG + PL D E VYISSLALLKML+HGR G PMEVMGLM
Sbjct: 1 MESLQRLLQGARMGTGMMG----DQPLVDNSECVYISSLALLKMLRHGRHGTPMEVMGLM 56
Query: 59 LGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPG 118
LGEFVDD+TV VVDVFAMPQSGTGVSVEAVD VFQ MMDMLKQTGR +MVVGWYHSHPG
Sbjct: 57 LGEFVDDFTVRVVDVFAMPQSGTGVSVEAVDPVFQKNMMDMLKQTGRPEMVVGWYHSHPG 116
Query: 119 FGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQN 178
FGCWLSSVD+NTQ+SFEQL RAVAVVVDPIQSVKGKVVIDAFRLI+PST+M QEPRQ
Sbjct: 117 FGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPSTLMMGQEPRQT 176
Query: 179 TSNIGLINKPNIQALIHGLNRHYYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKER 238
TSN+G INKP+IQALIHGL RHYYSL I+Y KT E ML+NLHK+ W GL + +F
Sbjct: 177 TSNLGHINKPSIQALIHGLGRHYYSLRINYKKTELEEIMLLNLHKQPWAHGLLLENFNSA 236
Query: 239 EEHNLGETQKMIKIAEQFTKRIXXXXXXXXXXXKTRYVGKQDPKRHLAETAEKLLEDNIV 298
E N KM ++EQ+T+R+ + +YVGKQDPK+HL +K +++NI
Sbjct: 237 AEKNHASIDKMKSLSEQYTERVQNEVTLSPEQLRIQYVGKQDPKKHLDAEVQKCIDNNIS 296
Query: 299 SVLTAGVNSVA 309
S+L ++SVA
Sbjct: 297 SMLACMLDSVA 307
>Hs5031981 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 310
Score = 388 bits (997), Expect = e-108
Identities = 190/291 (65%), Positives = 225/291 (77%)
Query: 21 TEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSG 80
T+ P DT E VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSG
Sbjct: 20 TDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSG 79
Query: 81 TGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSR 140
TGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWLS VD+NTQ+SFE L+ R
Sbjct: 80 TGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSER 139
Query: 141 AVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQNTSNIGLINKPNIQALIHGLNRH 200
AVAVVVDPIQSVKGKVVIDAFRLI+ + ++ EPRQ TSN+G +NKP+IQALIHGLNRH
Sbjct: 140 AVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRH 199
Query: 201 YYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIAEQFTKRI 260
YYS+ I+Y K E ML+NLHK+ W GL + D+ E +HN ++M+++A+ + K +
Sbjct: 200 YYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAV 259
Query: 261 XXXXXXXXXXXKTRYVGKQDPKRHLAETAEKLLEDNIVSVLTAGVNSVAIK 311
+ VGKQDPKRHL E + L+ NIV L A +++V K
Sbjct: 260 EEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310
>7296942 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 308
Score = 388 bits (996), Expect = e-108
Identities = 190/308 (61%), Positives = 234/308 (75%)
Query: 4 LQRMMMSQRAGMMGANATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFV 63
+ R++ A A T+ P+ DT E VYISSLALLKMLKHGRAGVPMEVMGLMLGEFV
Sbjct: 1 MDRLLRLGGAMPQAAPPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFV 60
Query: 64 DDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWL 123
DDYTV V+DVFAMPQ+GTGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWL
Sbjct: 61 DDYTVQVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWL 120
Query: 124 SSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQNTSNIG 183
S VD+NTQ+SFE L+ RAVAVVVDPIQSVKGKVVIDAFRLI+P+ ++ QEPRQ TSN+G
Sbjct: 121 SGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLG 180
Query: 184 LINKPNIQALIHGLNRHYYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNL 243
+ KP++QALIHGLNRHYYS++I+Y K E ML+NLHK+ W+ GL + D+ E N
Sbjct: 181 HLQKPSVQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINE 240
Query: 244 GETQKMIKIAEQFTKRIXXXXXXXXXXXKTRYVGKQDPKRHLAETAEKLLEDNIVSVLTA 303
+M+ +A+ + K + + VGKQDPKRHL E +K++++NIV L A
Sbjct: 241 DTVAEMLDLAKNYNKSLEDEEKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGA 300
Query: 304 GVNSVAIK 311
++++ K
Sbjct: 301 MLDTIVFK 308
>CE19527 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 312
Score = 377 bits (968), Expect = e-104
Identities = 187/298 (62%), Positives = 223/298 (74%)
Query: 14 GMMGANATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDV 73
G GAN + DT ETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNV+DV
Sbjct: 15 GTFGANPQDSNQVDTSETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVIDV 74
Query: 74 FAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKS 133
FAMPQSGTGVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWLS VD+NTQ+S
Sbjct: 75 FAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQS 134
Query: 134 FEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQNTSNIGLINKPNIQAL 193
FE L+ RAVAVVVDPIQSVKGKVVIDAFR I+P ++ NQEPRQ TSN+G + KP+IQAL
Sbjct: 135 FEALSDRAVAVVVDPIQSVKGKVVIDAFRTINPQSMALNQEPRQTTSNLGHLQKPSIQAL 194
Query: 194 IHGLNRHYYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIA 253
IHGLNRHYYS+ I Y E ML+NL+K W + + ++ + E N + M+K+A
Sbjct: 195 IHGLNRHYYSIPIAYRTHDLEQKMLLNLNKLSWMDAVSVENYSKCGEQNKEHLKAMLKLA 254
Query: 254 EQFTKRIXXXXXXXXXXXKTRYVGKQDPKRHLAETAEKLLEDNIVSVLTAGVNSVAIK 311
+ + K + + VGK DPKRH+A+ K+L DNIV L + + +++
Sbjct: 255 KNYKKALEDEKNMTDQELAIKNVGKMDPKRHIADEVSKMLNDNIVQSLAGMMATTSLQ 312
>At5g23540 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 308
Score = 377 bits (968), Expect = e-104
Identities = 192/308 (62%), Positives = 226/308 (73%), Gaps = 2/308 (0%)
Query: 1 MESLQRMMMSQRAGMMGANATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLG 60
ME LQR+ + G +G + + P DT E VYISSLALLKMLKHGRAGVPMEVMGLMLG
Sbjct: 1 MERLQRIFGA--GGGLGHASPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLG 58
Query: 61 EFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFG 120
EFVD+YTV VVDVFAMPQSGTGVSVEAVD VFQ M+DMLKQTGR +MVVGWYHSHPGFG
Sbjct: 59 EFVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFG 118
Query: 121 CWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQNTS 180
CWLS VD+NTQ+SFE LN RAVAVVVDPIQSVKGKVVIDAFR I+P T+M QEPRQ TS
Sbjct: 119 CWLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRSINPQTIMLGQEPRQTTS 178
Query: 181 NIGLINKPNIQALIHGLNRHYYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREE 240
N+G +NKP+IQALIHGLNRHYYS+ I+Y K E ML+NLHK++W GL + F +
Sbjct: 179 NLGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEKMLLNLHKKKWTDGLTLRRFDTHSK 238
Query: 241 HNLGETQKMIKIAEQFTKRIXXXXXXXXXXXKTRYVGKQDPKRHLAETAEKLLEDNIVSV 300
N Q+M+ +A ++ K + VG+QD K+HL E L+ NIV
Sbjct: 239 TNEQTVQEMLSLAAKYNKAVQEEDELSPEKLAIVNVGRQDAKKHLEEHVSNLMSSNIVQT 298
Query: 301 LTAGVNSV 308
L +++V
Sbjct: 299 LGTMLDTV 306
>ECU11g0570 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 294
Score = 313 bits (802), Expect = 2e-85
Identities = 163/290 (56%), Positives = 203/290 (69%), Gaps = 9/290 (3%)
Query: 13 AGMMGANATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVD 72
+G +G + E P D ETV ISSLALLKMLKHGRAG+P+EVMGLMLGEFVD+YTV VVD
Sbjct: 3 SGFVGPDDGE-PTSDASETVQISSLALLKMLKHGRAGIPLEVMGLMLGEFVDEYTVKVVD 61
Query: 73 VFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQK 132
VFAMPQSGT V+VE+VD +FQ +MM +LK TGR + VVGWYHSHPGFGCWLS+VD++TQ+
Sbjct: 62 VFAMPQSGTNVTVESVDPIFQMEMMSILKATGRHETVVGWYHSHPGFGCWLSTVDISTQQ 121
Query: 133 SFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPSTVMRNQEPRQNTSNIGLINKPNIQA 192
SFE+L RAVAVVVDPIQSVKGKVVIDAFRLID + EPRQ TSNIG + P + +
Sbjct: 122 SFEKLCKRAVAVVVDPIQSVKGKVVIDAFRLIDNQLGVLGGEPRQVTSNIGYLKTPTLIS 181
Query: 193 LIHGLNRHYYSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKI 252
+IHGLN+HYYS NI K E ML+NLH++ W LK+ D + + E + +K+
Sbjct: 182 IIHGLNKHYYSFNITCRKNDFEQKMLLNLHRKTWADNLKLGDVRSKRE-------EALKL 234
Query: 253 AEQFTKRIXXXXXXXXXXXKTRYVGKQDPKRHLAETAEK-LLEDNIVSVL 301
E + K VG+ D +R L E E+ ++E+ I S+L
Sbjct: 235 IESYGKAFEEEKNLAGKNPDMAKVGRIDYRRRLLEKCEESIMENTIYSLL 284
>CE00707 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 319
Score = 295 bits (755), Expect = 6e-80
Identities = 155/292 (53%), Positives = 196/292 (67%), Gaps = 11/292 (3%)
Query: 27 DTKETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVE 86
DT ETV ISSLALLKML+H R+G+P+EVMGLMLG+FVDDYT+NV DVFAMPQSGT V+VE
Sbjct: 24 DTSETVNISSLALLKMLRHARSGIPLEVMGLMLGDFVDDYTINVTDVFAMPQSGTSVTVE 83
Query: 87 AVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVV 146
+VD V+Q K MD+LK GR + VVGWYHSHPGFGCWLSSVDVNTQ+SFE L+ RAVAVVV
Sbjct: 84 SVDPVYQTKHMDLLKLVGRTENVVGWYHSHPGFGCWLSSVDVNTQQSFEALHPRAVAVVV 143
Query: 147 DPIQSVKGKVVIDAFRLIDPSTVM-----RNQEPRQNTSNIGLINKPNIQALIHGLNRHY 201
DPIQSVKGKV++DAFR ++P + EPRQ TSN+G + KP++ +++HGL Y
Sbjct: 144 DPIQSVKGKVMLDAFRSVNPLNLQIRPLAPTAEPRQTTSNLGHLTKPSLISVVHGLGTKY 203
Query: 202 YSLNIDYHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIAEQFTKRIX 261
YSLN+ Y S E MLM L+K+ W L M + E E+ + + + K+ F K I
Sbjct: 204 YSLNVAYRMGSNEQKMLMCLNKKSWYDQLNMSTYSELEKKQEEKFKSINKLIAVFNKDID 263
Query: 262 XXXXXXXXXXK------TRYVGKQDPKRHLAETAEKLLEDNIVSVLTAGVNS 307
K + GK + K+ L LL D++ LTA +N+
Sbjct: 264 EVKEKPIADKKGKTQEEVKKFGKINAKQQLQMITSSLLNDSLCHQLTAMINA 315
>7300154 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 327
Score = 144 bits (363), Expect = 2e-34
Identities = 85/228 (37%), Positives = 125/228 (54%), Gaps = 11/228 (4%)
Query: 32 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDV 91
+ IS+LALLKM+ H R+G +EVMGLMLG+ V+D T+ V+D FA+P GT V A
Sbjct: 52 IKISALALLKMVMHARSGGTLEVMGLMLGK-VEDNTMIVMDAFALPVEGTETRVNAQAQA 110
Query: 92 FQ--AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPI 149
++ M+ K+ GR + VGWYHSHPG+GCWLS +DV+TQ + VA+VVDP+
Sbjct: 111 YEYMTAYMEAAKEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPV 170
Query: 150 QSVK-GKVVIDAFRLIDPSTVMRNQEPRQ-NTSNIGLINKPNIQALIHGLNRHYYSLNID 207
++V GKV + AFR N+EP + T + I + + YY L I
Sbjct: 171 RTVSAGKVCLGAFRTYPKGYKPPNEEPSEYQTIPLNKIEDFGVHC------KQYYPLEIS 224
Query: 208 YHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIAEQ 255
Y K++ + +L +L + W + L E+ G+ + + EQ
Sbjct: 225 YFKSALDRRLLDSLWNKYWVNTLGSSGLLTNTEYTTGQIMDLSEKLEQ 272
>Hs5803046 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 334
Score = 135 bits (341), Expect = 6e-32
Identities = 81/226 (35%), Positives = 124/226 (54%), Gaps = 11/226 (4%)
Query: 34 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTG--VSVEAVDDV 91
IS+LALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V+ +A
Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115
Query: 92 FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 151
+ A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP ++
Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175
Query: 152 VK-GKVVIDAFRLIDPSTVMRNQEPRQ-NTSNIGLINKPNIQALIHGLNRHYYSLNIDYH 209
+ GKV + AFR ++ P + T + I + + YY+L + Y
Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHC------KQYYALEVSYF 229
Query: 210 KTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIAEQ 255
K+S + +L L + W + L ++ G+ + + EQ
Sbjct: 230 KSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQ 275
>At1g71230 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 358
Score = 135 bits (341), Expect = 6e-32
Identities = 86/228 (37%), Positives = 126/228 (54%), Gaps = 11/228 (4%)
Query: 32 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDV 91
V IS+LALLKM+ H R+G +E+MGLM G+ D T+ V+D FA+P GT V A DD
Sbjct: 59 VKISALALLKMVVHARSGGTIEIMGLMQGK-TDGDTIIVMDAFALPVEGTETRVNAQDDA 117
Query: 92 FQ--AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPI 149
++ + K GR + VVGWYHSHPG+GCWLS +DV+TQ+ +Q +AVV+DP
Sbjct: 118 YEYMVEYSQTNKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQRLNQQHQEPFLAVVIDPT 177
Query: 150 QSVK-GKVVIDAFRLIDPSTVMRNQEPRQNTSNIGLINKPNIQAL-IHGLNRHYYSLNID 207
++V GKV I AFR + P + S I I+ +H + YYSL++
Sbjct: 178 RTVSAGKVEIGAFRTYSKG----YKPPDEPVSEYQTIPLNKIEDFGVH--CKQYYSLDVT 231
Query: 208 YHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIAEQ 255
Y K+S + ++L L + W + L ++ G+ + + EQ
Sbjct: 232 YFKSSLDSHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQ 279
>At1g22920 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 357
Score = 134 bits (336), Expect = 2e-31
Identities = 83/228 (36%), Positives = 123/228 (53%), Gaps = 11/228 (4%)
Query: 32 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDV 91
V+IS+LALLKM+ H R+G +E+MGLM G+ D T+ V+D FA+P GT V A D
Sbjct: 59 VHISALALLKMVVHARSGGTIEIMGLMQGKTEGD-TIIVMDAFALPVEGTETRVNAQSDA 117
Query: 92 FQ--AKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPI 149
++ + K GR + VVGWYHSHPG+GCWLS +DV+TQ +Q +AVV+DP
Sbjct: 118 YEYMVEYSQTSKLAGRLENVVGWYHSHPGYGCWLSGIDVSTQMLNQQYQEPFLAVVIDPT 177
Query: 150 QSVK-GKVVIDAFRLI-DPSTVMRNQEPRQNTSNIGLINKPNIQALIHGLNRHYYSLNID 207
++V GKV I AFR + + + T + I + + YYSL+I
Sbjct: 178 RTVSAGKVEIGAFRTYPEGHKISDDHVSEYQTIPLNKIEDFGVHC------KQYYSLDIT 231
Query: 208 YHKTSAEMNMLMNLHKEQWQSGLKMHDFKEREEHNLGETQKMIKIAEQ 255
Y K+S + ++L L + W + L ++ G+ + + EQ
Sbjct: 232 YFKSSLDSHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQ 279
>CE06722 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 368
Score = 122 bits (305), Expect = 9e-28
Identities = 72/203 (35%), Positives = 114/203 (55%), Gaps = 11/203 (5%)
Query: 32 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDV 91
+ IS++ALLKM H + G +E+MGL+ G +D + ++DVFA+P GT V A
Sbjct: 56 IKISAIALLKMTMHAKRGGNLEIMGLLQGR-IDANSFIILDVFALPVEGTETRVNAQAQA 114
Query: 92 FQAKMM--DMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPI 149
++ + +M GR + VVGWYHSHPG+GCWLS +DV+TQ ++ VA+V+DP+
Sbjct: 115 YEYMTVYSEMCDTEGRKEKVVGWYHSHPGYGCWLSGIDVSTQTLNQKFQEPWVAIVIDPL 174
Query: 150 QSVK-GKVVIDAFRLIDPSTVMRNQEPRQNTSNIGLINKPNIQALIHGLN-RHYYSLNID 207
+++ GKV I AFR + P + S P + G++ + YYSL++
Sbjct: 175 RTMSAGKVDIGAFRTYPEGYRPPDDVPSEYQS------IPLAKIEDFGVHCKRYYSLDVS 228
Query: 208 YHKTSAEMNMLMNLHKEQWQSGL 230
+ K+ + ++L +L W S L
Sbjct: 229 FFKSQLDAHILTSLWNSYWISTL 251
>SPAC1687.13c [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 299
Score = 119 bits (297), Expect = 7e-27
Identities = 77/230 (33%), Positives = 122/230 (52%), Gaps = 15/230 (6%)
Query: 31 TVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDD 90
+V IS++ALLKML+H G+P+EVMG + G+ V+ ++ ++D FA+P GT V A ++
Sbjct: 34 SVKISAVALLKMLRHVSQGMPLEVMGYVQGK-VEGASLIILDSFALPVEGTETRVNAHEE 92
Query: 91 V--FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDP 148
+ + + K R + V+GWYHSHP +GCWLS VDV TQ+ ++ VAVV+DP
Sbjct: 93 AQEYSVQYHTLCKSVYRHENVIGWYHSHPNYGCWLSGVDVETQRQNQKYQDPFVAVVLDP 152
Query: 149 IQSVKGKVV-IDAFRLIDPSTVMRNQEPRQNTSNIGLINKPNIQALIHGLNRH-YYSLNI 206
+S++ V I AFR + ++ ++ N P+ + G + YYSL I
Sbjct: 153 KRSLESPYVNIGAFRTYPVGNDGSIRTKSRHHPSVLFKNLPSSKIEDAGAHAEAYYSLPI 212
Query: 207 DYHKTSAEMNMLMNLHKEQW----------QSGLKMHDFKEREEHNLGET 246
Y + AE + L W Q+ +HD ++ +H + ET
Sbjct: 213 TYFHSKAEKKVTEFLRNRNWSRSITECSILQNNEFLHDSEKLIDHLIHET 262
>Hs17463759 [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 254
Score = 105 bits (261), Expect = 1e-22
Identities = 73/211 (34%), Positives = 109/211 (51%), Gaps = 16/211 (7%)
Query: 34 ISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGV--SVEAVDDV 91
IS+LALLKM+ H R+G +EVMGLM G+ VD T ++ F +P GT + EAV
Sbjct: 21 ISALALLKMMMHARSGGNLEVMGLMPGK-VDGETTIIMGSFTLPVEGTETRENAEAVAYE 79
Query: 92 FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 151
+ A + K+ GR + +GWY+ HPG GCWLS + TQ ++ AVV+DP ++
Sbjct: 80 YMATYTENAKKVGRLKNAIGWYYRHPGHGCWLSG--IITQLLNKRFREPFTAVVIDPTRT 137
Query: 152 VK-GKVVIDAFRLIDPSTVMRNQEPRQ-NTSNIGLINKPNIQALIHGLNRHYYSLNIDYH 209
+ GKV +DAFR ++ P + T + I +Q + YY+L + Y
Sbjct: 138 ISAGKVNLDAFRTYPKGYKPPDEGPSEYQTILLNKIEDVFVQC------KQYYALEVLYF 191
Query: 210 KTSAEMNMLMNLHKEQWQSGLKMHDFKEREE 240
K S +L L + W + HD K ++
Sbjct: 192 KFSLGCKLLELLWNKYW---AETHDRKSEDK 219
>YDL216c [OT] KOG1554 COP9 signalosome subunit CSN5
Length = 455
Score = 85.5 bits (210), Expect = 9e-17
Identities = 54/160 (33%), Positives = 91/160 (56%), Gaps = 17/160 (10%)
Query: 19 NATEVPLDDTKETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQ 78
++T++P + V IS L+ K+ + G +E+MG+++G + D V V+D F +P
Sbjct: 76 SSTDIP---SYTHVLISKLSCEKITHYAVRGGNIEIMGILMGFTLKDNIV-VMDCFNLPV 131
Query: 79 SGTGVSVEAVDDVFQAKMM---DMLKQT----GRDQM-----VVGWYHSHPGFGCWLSSV 126
GT V A + ++ + +M GRD VVGW+HSHPG+ CWLS++
Sbjct: 132 VGTETRVNAQLESYEYMVQYIDEMYNHNDGGDGRDYKGAKLNVVGWFHSHPGYDCWLSNI 191
Query: 127 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVV-IDAFRLID 165
D+ TQ ++ VA+VVDP++S++ K++ + AFR I+
Sbjct: 192 DIQTQDLNQRFQDPYVAIVVDPLKSLEDKILRMGAFRTIE 231
>Hs4503515 [J] KOG1560 Translation initiation factor 3 subunit h (eIF-3h)
Length = 352
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/140 (29%), Positives = 77/140 (54%), Gaps = 5/140 (3%)
Query: 26 DDTKETVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVNVVDVFAMPQSGTGV 83
D + V I L +LK++KH + G EV+ G++LG V+D + + + F PQ T
Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQH-TED 90
Query: 84 SVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVA 143
+ + +Q +MM L+ D + VGWY S +G +++ +++Q S++ +V
Sbjct: 91 DADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESVV 149
Query: 144 VVVDPIQSVKGKVVIDAFRL 163
++ DPI++ +G + + A+RL
Sbjct: 150 LIYDPIKTAQGSLSLKAYRL 169
>Hs13236583 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 316
Score = 58.5 bits (140), Expect = 1e-08
Identities = 43/167 (25%), Positives = 68/167 (39%), Gaps = 32/167 (19%)
Query: 30 ETVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDD------YTVNVVDVFAMPQSGTGV 83
+ V++ S A L L H + EVMGL +GE DD + ++ + + V
Sbjct: 10 QAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAEKVDAV 69
Query: 84 SVEAVDDVFQAKMMDMLKQ----------------------TGRDQMVVGWYHSHPGFGC 121
+ + V + D K TGR VVGWYHSHP
Sbjct: 70 RIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITV 129
Query: 122 WLSSVDVNTQKSFEQLNSRAVAVV----VDPIQSVKGKVVIDAFRLI 164
W S VDV TQ ++ ++ V ++ ++ + G+V+ F+ I
Sbjct: 130 WPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSI 176
>At1g10840 [J] KOG1560 Translation initiation factor 3 subunit h (eIF-3h)
Length = 346
Score = 58.2 bits (139), Expect = 2e-08
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 2/134 (1%)
Query: 32 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDV 91
V I LA+LK++KH + P V G +LG V + V + F P +EA
Sbjct: 34 VQIEGLAVLKIIKHCKEFSPTLVTGQLLGLDVGS-VLEVTNCFPFPVRDDDEEIEADGAN 92
Query: 92 FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 151
+Q +MM L++ D VGWY S G + + + T ++++ R V ++ DP ++
Sbjct: 93 YQLEMMRCLREVNVDNNTVGWYQS-TVLGSYQTVELIETFMNYQENIKRCVCIIYDPSKA 151
Query: 152 VKGKVVIDAFRLID 165
G + + A +L D
Sbjct: 152 DLGVLALKALKLSD 165
>At1g10600 [T] KOG2880 SMAD6 interacting protein AMSH contains JAB/MPN/Mov34
domain
Length = 271
Score = 56.2 bits (134), Expect = 6e-08
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 59 LGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPG 118
L F++ V + Q T S +A+++V + Q R+ VGW H+HP
Sbjct: 77 LAAFLERGIFYVTTLIIPKQESTSNSCQAMNEVEVFSI-----QNERELYPVGWIHTHPS 131
Query: 119 FGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDP 166
GC++SSVD++T S++ + A A+VV P S K + F+L DP
Sbjct: 132 QGCFMSSVDLHTHYSYQVMVPEAFAIVVAPTDSSKSYGI---FKLTDP 176
>SPAC19B12.10 [T] KOG2880 SMAD6 interacting protein AMSH contains JAB/MPN/Mov34
domain
Length = 435
Score = 51.6 bits (122), Expect = 1e-06
Identities = 25/77 (32%), Positives = 47/77 (60%), Gaps = 8/77 (10%)
Query: 102 QTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAF 161
Q + + +GW H+HP C++SSVD++T S++ + A+A+V+ P ++ G F
Sbjct: 329 QDKHNLLTLGWIHTHPTQTCFMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSG-----IF 383
Query: 162 RLIDP---STVMRNQEP 175
RL+DP T+++ ++P
Sbjct: 384 RLLDPEGLQTIVKCRKP 400
>At1g48790 [T] KOG2880 SMAD6 interacting protein AMSH contains JAB/MPN/Mov34
domain
Length = 505
Score = 51.6 bits (122), Expect = 1e-06
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 13/127 (10%)
Query: 52 MEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVG 111
+E G++ G + + + + Q T S +++F+ Q + +G
Sbjct: 355 LETCGILAGS-LKNRKFYITALIIPKQESTSDSATNEEEIFEV-------QDKQSLFPLG 406
Query: 112 WYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDPS--TV 169
W H+HP C++SS+DV+T S++ + AVA+V+ P S + + FRL P TV
Sbjct: 407 WIHTHPTQSCFMSSIDVHTHYSYQIMLPEAVAIVMAPQDSSRNHGI---FRLTTPGGMTV 463
Query: 170 MRNQEPR 176
+RN + R
Sbjct: 464 IRNCDRR 470
>Hs16158201_2 [O] KOG1555 26S proteasome regulatory complex subunit RPN11
Length = 256
Score = 50.1 bits (118), Expect = 4e-06
Identities = 41/121 (33%), Positives = 58/121 (47%), Gaps = 5/121 (4%)
Query: 32 VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVD-DYTVNVVDVFAMPQSGTGVSVEAVDD 90
V ++S ALL M H + EV+GL+ G + + D V V TG+ E +D
Sbjct: 5 VKVASEALLIMDLHAHVSMA-EVIGLLGGRYSEVDKVVEVCAAEPCNSLSTGLQCE-MDP 62
Query: 91 VFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQ 150
V Q + + L G V+GWYHSHP F S D++TQ ++ SR A + I
Sbjct: 63 VSQTQASETLAVRGFS--VIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMIV 120
Query: 151 S 151
S
Sbjct: 121 S 121
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,907,225
Number of Sequences: 60738
Number of extensions: 601968
Number of successful extensions: 1589
Number of sequences better than 1.0e-05: 23
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1546
Number of HSP's gapped (non-prelim): 24
length of query: 311
length of database: 30,389,216
effective HSP length: 106
effective length of query: 205
effective length of database: 23,950,988
effective search space: 4909952540
effective search space used: 4909952540
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)