ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3636 good C KOG2617 Energy production and conversion Citrate synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3636 1261668 1260250 -473
(473 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR001w [C] KOG2617 Citrate synthase 626 e-179
SPAC6C3.04 [C] KOG2617 Citrate synthase 432 e-121
Hs4758076 [C] KOG2617 Citrate synthase 419 e-117
YNR001c [C] KOG2617 Citrate synthase 412 e-115
7290712 [C] KOG2617 Citrate synthase 409 e-114
YCR005c [C] KOG2617 Citrate synthase 404 e-112
CE00513 [C] KOG2617 Citrate synthase 388 e-107
At2g44350 [C] KOG2617 Citrate synthase 387 e-107
At3g60100 [C] KOG2617 Citrate synthase 381 e-105
7299562 [C] KOG2617 Citrate synthase 340 4e-93
At2g42790 [C] KOG2617 Citrate synthase 100 8e-21
At3g58750 [C] KOG2617 Citrate synthase 94 6e-19
At3g58740 [C] KOG2617 Citrate synthase 85 2e-16
Hs17434182 [C] KOG2617 Citrate synthase 77 6e-14
>YPR001w [C] KOG2617 Citrate synthase
Length = 486
Score = 626 bits (1615), Expect = e-179
Identities = 310/470 (65%), Positives = 377/470 (79%), Gaps = 5/470 (1%)
Query: 4 KNFTQTRLFHSSRHLLNLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGN 63
++F + + SS L LK A+ +VIPK+R+ + +K + VG ITI SV+ GMRGN
Sbjct: 14 RSFNSSAIIKSSA--LTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGN 71
Query: 64 QSMYWESTTLDPNEGIRFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEE 123
QSM+W+ T+LDP GI+F G TI ECQ LP D FLPESMLWLLMTG VP+ +
Sbjct: 72 QSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDN--FLPESMLWLLMTGGVPTFQ 129
Query: 124 QVRKLTQELAERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIG 183
Q +ELA RG KLP +TEK+L+SLP+DMHPMTQLAI LASMNKGS+FA YQ+G IG
Sbjct: 130 QAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIG 189
Query: 184 KMDYWEYVYEDVLNLIAALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTV-S 242
KM++W+ ED LNLIA+LP +TG+IYSNI N+G PLG Y+ E DW NI SLLGMT +
Sbjct: 190 KMEFWKDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGT 249
Query: 243 DSVNMHSLTQERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMG 302
+S N +LT ++S DF+NL+RLY GIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMG
Sbjct: 250 NSSNTCNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMG 309
Query: 303 LAGPLHGLAAQEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDP 362
LAGPLHGLAAQEVVRFL+EM ++ S+ +++++YLWK+LNS+RVIPGYGHAVLRKPDP
Sbjct: 310 LAGPLHGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDP 369
Query: 363 RFDAMLNFAEKRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHY 422
RF AML FA+KRP EF++D V LM++L++IAPKVL EHGK+KNP+PNVDSASGILFYHY
Sbjct: 370 RFTAMLEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHY 429
Query: 423 GIDQLLFFTVIFGCSRAMGPLSQLVWDRILGLPIERPKSIDLNTIKKICK 472
GI +LLFFTVIFGCSRAMGPL+QLVWDRILGLPIERPKS++L ++ + K
Sbjct: 430 GIRELLFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTK 479
>SPAC6C3.04 [C] KOG2617 Citrate synthase
Length = 473
Score = 432 bits (1110), Expect = e-121
Identities = 223/452 (49%), Positives = 303/452 (66%), Gaps = 24/452 (5%)
Query: 20 NLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTLDPNEGI 79
+LK +A++IP+++ E+ + +G++TI + G RG +S+ WE + LDPNEGI
Sbjct: 41 SLKDRLAELIPEKQAEIKKFRAEHGQDVIGEVTINQMYGGARGVRSLIWEGSVLDPNEGI 100
Query: 80 RFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELAERGAKL 139
RF G TI ECQKLLP +P NGK + LPES+ WLL+TGE+P+ QV+ L+ + A R ++L
Sbjct: 101 RFRGYTIPECQKLLPSSP--NGK-QPLPESLFWLLVTGEIPTLSQVQALSADWAAR-SQL 156
Query: 140 PPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVYEDVLNLI 199
P E+L+ P +HPM Q ++A+ ++ S FA+ Y+ G + K DYW+Y YED ++LI
Sbjct: 157 PKFVEELIDRCPPTLHPMAQFSLAVTALEHDSAFAKAYERG-MNKHDYWKYEYEDCMDLI 215
Query: 200 AALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQERSNDFV 259
A I G+IY N+ DG + ++KD SYN A++LG + +FV
Sbjct: 216 AKTVPIAGRIYRNLYRDGV-VAPIQMDKDHSYNFANVLGFA-------------NNEEFV 261
Query: 260 NLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFL 319
L+RLY IH DHEGGNVSAHT HLVGSALS P+LS ++ + GLAGPLHGLA QEV+ FL
Sbjct: 262 ELMRLYLTIHADHEGGNVSAHTGHLVGSALSSPFLSMAASLNGLAGPLHGLANQEVLNFL 321
Query: 320 VEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFA-EKRPKEF 378
+ M+K++ + + ++ YLWK+LNS RV+PGYGHAVLRK DPR+ A FA E PK
Sbjct: 322 ITMKKEIGDDLSEETIKSYLWKLLNSGRVVPGYGHAVLRKTDPRYTAQREFALEHLPK-- 379
Query: 379 KSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTVIFGCSR 438
D QL+ +L +I P VL EHGKTKNPYPNVDS SG+L +YG+ + F+TV+FG SR
Sbjct: 380 --DPMFQLVSRLYEIVPGVLTEHGKTKNPYPNVDSHSGVLLQYYGLKEQSFYTVLFGVSR 437
Query: 439 AMGPLSQLVWDRILGLPIERPKSIDLNTIKKI 470
+G SQL+WDR LGLPIERPKS +KK+
Sbjct: 438 TLGVASQLIWDRALGLPIERPKSFSTEALKKM 469
>Hs4758076 [C] KOG2617 Citrate synthase
Length = 466
Score = 419 bits (1078), Expect = e-117
Identities = 214/457 (46%), Positives = 300/457 (64%), Gaps = 22/457 (4%)
Query: 13 HSSRHLLNLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTT 72
H+S NLK +AD+IPK + + ++ VG IT+ + GMRG + + +E++
Sbjct: 25 HASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSV 84
Query: 73 LDPNEGIRFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQEL 132
LDP+EGIRF G +I ECQKLLP A G E LPE + WLL+TG +P+EEQV L++E
Sbjct: 85 LDPDEGIRFRGFSIPECQKLLPKA---KGGEEPLPEGLFWLLVTGCIPTEEQVSWLSKEW 141
Query: 133 AERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVY 192
A+R A LP H +L + P ++HPM+QL+ A+ ++N S FA+ Y G I + YWE +Y
Sbjct: 142 AKRAA-LPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFAQAYARG-ISRTKYWELIY 199
Query: 193 EDVLNLIAALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQ 252
ED ++LIA LP + KIY N+ +G +G + DWS+N ++LG T
Sbjct: 200 EDSVDLIAKLPCVAAKIYRNLYWEGSGIGAIDSNLDWSHNFTNMLGYT------------ 247
Query: 253 ERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAA 312
+ F L+RLY IH DHEGGNVSAHT+HLVGSALSDPYLS+++ + GLAGPLHGLA
Sbjct: 248 --DHQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLAN 305
Query: 313 QEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAE 372
QEV+ +L +++K+V + +++ +Y+W LNS RV+PGYGHAVLRK DPR+ FA
Sbjct: 306 QEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFA- 364
Query: 373 KRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTV 432
K +D +L+ QL +I P VL E GK KNP+PNVD+ SG+L +YG+ ++ ++TV
Sbjct: 365 --LKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTV 422
Query: 433 IFGCSRAMGPLSQLVWDRILGLPIERPKSIDLNTIKK 469
+FG SRA+G L+QL+W R LG P+ERPKS+ + K
Sbjct: 423 LFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMK 459
>YNR001c [C] KOG2617 Citrate synthase
Length = 479
Score = 412 bits (1060), Expect = e-115
Identities = 212/460 (46%), Positives = 297/460 (64%), Gaps = 23/460 (5%)
Query: 13 HSSRHLLNLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTT 72
+SS LK A++IP + EE+ KK +G++ + GMRG + + WE +
Sbjct: 37 YSSASEQTLKERFAEIIPAKAEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSV 96
Query: 73 LDPNEGIRFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQEL 132
LDP EGIRF G+TI E Q+ LP A G E LPE++ WLL+TGE+P++ QV+ L+ +L
Sbjct: 97 LDPEEGIRFRGRTIPEIQRELPKA---EGSTEPLPEALFWLLLTGEIPTDAQVKALSADL 153
Query: 133 AERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVY 192
A R +++P H +LL SLP+D+HPM Q +IA+ ++ S FA+ Y +G + K +YW Y +
Sbjct: 154 AAR-SEIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQG-VSKKEYWSYTF 211
Query: 193 EDVLNLIAALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQ 252
ED L+L+ LP I KIY N+ DG+ + + D+ N+A LLG
Sbjct: 212 EDSLDLLGKLPVIASKIYRNVFKDGK-ITSTDPNADYGKNLAQLLGY------------- 257
Query: 253 ERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAA 312
+ DF++L+RLY IH DHEGGNVSAHTTHLVGSALS PYLS ++G+ GLAGPLHG A
Sbjct: 258 -ENKDFIDLMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRAN 316
Query: 313 QEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAE 372
QEV+ +L ++ ++V + + +E+YLW LN+ RV+PGYGHAVLRK DPR+ A FA
Sbjct: 317 QEVLEWLFKLREEVKGDYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFA- 375
Query: 373 KRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTV 432
K F +L+ + ++AP VL +HGKTKNP+PNVDS SG+L +YG+ + F+TV
Sbjct: 376 --LKHFPDYELFKLVSTIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTV 433
Query: 433 IFGCSRAMGPLSQLVWDRILGLPIERPKSIDLNTIKKICK 472
+FG +RA+G L QL+ DR +G PIERPKS K++ K
Sbjct: 434 LFGVARAIGVLPQLIIDRAVGAPIERPKSFSTEKYKELVK 473
>7290712 [C] KOG2617 Citrate synthase
Length = 464
Score = 409 bits (1051), Expect = e-114
Identities = 209/451 (46%), Positives = 297/451 (65%), Gaps = 22/451 (4%)
Query: 20 NLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTLDPNEGI 79
+L+ +A +P+ +E + + +K K+G+ TI + GMRG +++ E++ LD +EGI
Sbjct: 33 SLRDVLAAKVPQEQERVKNFRKQHGATKMGETTIDMMYGGMRGIKALVTETSVLDADEGI 92
Query: 80 RFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELAERGAKL 139
RF G +I ECQK+LP A +G E LPE + WLL+TGEVP++ QV++L++E AER A L
Sbjct: 93 RFRGLSIPECQKVLPAA---DGGTEPLPEGLFWLLLTGEVPTKSQVQQLSREWAERAA-L 148
Query: 140 PPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVYEDVLNLI 199
P H +L ++P +HPM+Q A A+ ++N S FA+ Y +G + K YWEYVYED ++LI
Sbjct: 149 PQHVVTMLNNMPTTLHPMSQFAAAVTALNHDSKFAKAYSDG-VHKSKYWEYVYEDSMDLI 207
Query: 200 AALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQERSNDFV 259
A LP + IY N G+ + DWS N +LG + F
Sbjct: 208 AKLPVVAATIYCNTYRGGKGSRSIDSSLDWSANFVKMLGYD--------------NAPFT 253
Query: 260 NLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFL 319
L+RLY IH DHEGGNVSAHT HLVGSALSDPYLS+++G+ GLAGPLHGLA QEV+ +L
Sbjct: 254 ELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWL 313
Query: 320 VEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAEKRPKEFK 379
+++K+ + + +Q++EY+WK L S +V+PGYGHAVLRK DPR+ FA K E
Sbjct: 314 RKLQKEAGNNPSEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPE-- 371
Query: 380 SDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTVIFGCSRA 439
D QL+ ++ ++ P +L E GK KNP+PNVD+ SG+L +YG+ ++ ++TV+FG SRA
Sbjct: 372 -DETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRA 430
Query: 440 MGPLSQLVWDRILGLPIERPKSIDLNTIKKI 470
+G L+ LVWDR LGLPIERPKS + + K+
Sbjct: 431 LGVLASLVWDRALGLPIERPKSFSTDLLVKM 461
>YCR005c [C] KOG2617 Citrate synthase
Length = 460
Score = 404 bits (1039), Expect = e-112
Identities = 209/452 (46%), Positives = 289/452 (63%), Gaps = 23/452 (5%)
Query: 21 LKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTLDPNEGIR 80
LK +++ P +++ K K+ D+ + V GMRG WE + LDP +GIR
Sbjct: 26 LKERFSEIYPIHAQDVRQFVKEHGKTKISDVLLEQVYGGMRGIPGSVWEGSVLDPEDGIR 85
Query: 81 FHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELAERGAKLP 140
F G+TIA+ QK LP A G + LPE++ WLL+TGEVP++ QV L+ +L R ++LP
Sbjct: 86 FRGRTIADIQKDLPKA---KGSSQPLPEALFWLLLTGEVPTQAQVENLSADLMSR-SELP 141
Query: 141 PHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVYEDVLNLIA 200
H +LL +LP+D+HPM Q +IA+ ++ S FA+ Y +G I K DYW Y +ED L+L+
Sbjct: 142 SHVVQLLDNLPKDLHPMAQFSIAVTALESESKFAKAYAQG-ISKQDYWSYTFEDSLDLLG 200
Query: 201 ALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQERSNDFVN 260
LP I KIY N+ DG+ +G + D++ N+ +L+G + DFV+
Sbjct: 201 KLPVIAAKIYRNVFKDGK-MGEVDPNADYAKNLVNLIG--------------SKDEDFVD 245
Query: 261 LVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLV 320
L+RLY IH DHEGGNVSAHT+HLVGSALS PYLS +SG+ GLAGPLHG A QEV+ +L
Sbjct: 246 LMRLYLTIHSDHEGGNVSAHTSHLVGSALSSPYLSLASGLNGLAGPLHGRANQEVLEWLF 305
Query: 321 EMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAEKRPKEFKS 380
++++V+ + +E+YLW LNS RVIPGYGHAVLRK DPR+ A FA F
Sbjct: 306 ALKEEVNDDYSKDTIEKYLWDTLNSGRVIPGYGHAVLRKTDPRYMAQRKFA---MDHFPD 362
Query: 381 DAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTVIFGCSRAM 440
+L+ + ++AP VL EHGKTKNP+PNVD+ SG+L +YG+ + F+TV+FG SRA
Sbjct: 363 YELFKLVSSIYEVAPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLKESSFYTVLFGVSRAF 422
Query: 441 GPLSQLVWDRILGLPIERPKSIDLNTIKKICK 472
G L+QL+ DR +G IERPKS K++ K
Sbjct: 423 GILAQLITDRAIGASIERPKSYSTEKYKELVK 454
>CE00513 [C] KOG2617 Citrate synthase
Length = 468
Score = 388 bits (996), Expect = e-107
Identities = 207/451 (45%), Positives = 284/451 (62%), Gaps = 22/451 (4%)
Query: 20 NLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTLDPNEGI 79
NLK ++ IP ++ + V ++ I + GMR + M E++ LDP EGI
Sbjct: 34 NLKEVLSKKIPAHNAKVKSFRTEHGSTVVQNVNIDMIYGGMRSMKGMVTETSVLDPEEGI 93
Query: 80 RFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELAERGAKL 139
RF G +I ECQKLLP A G E LPE++ WLL TG+VPSE Q +T+E R A L
Sbjct: 94 RFRGYSIPECQKLLPKA---KGGEEPLPEAIWWLLCTGDVPSEAQTAAITKEWNAR-ADL 149
Query: 140 PPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVYEDVLNLI 199
P H ++L + P ++HPM Q A+A++N S FA Y G + K YWEY YED ++L+
Sbjct: 150 PTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFAGAYARG-VAKASYWEYAYEDSMDLL 208
Query: 200 AALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQERSNDFV 259
A LP + IY N+ DG + + +KDWS N +S+LG D + F
Sbjct: 209 AKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSSMLGY--DDPL------------FA 254
Query: 260 NLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFL 319
L+RLY IH DHEGGNVSAHT+HLVGSALSDPYLS+S+ + GLAGPLHGLA QEV+ FL
Sbjct: 255 ELMRLYLVIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMAGLAGPLHGLANQEVLVFL 314
Query: 320 VEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAEKRPKEFK 379
++ ++ +Q++E++WK L S +V+PGYGHAVLRK DPR++ FA K
Sbjct: 315 NKIVGEIGFNYTEEQLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFA---LKHLP 371
Query: 380 SDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTVIFGCSRA 439
+D +L+ L +I P +L E GK KNP+PNVDS SG+L ++G+ ++ F+TV+FG SRA
Sbjct: 372 NDDLFKLVSTLYKITPGILLEQGKAKNPWPNVDSHSGVLLQYFGMTEMSFYTVLFGVSRA 431
Query: 440 MGPLSQLVWDRILGLPIERPKSIDLNTIKKI 470
+G LSQL+W R +GLP+ERPKS + + K+
Sbjct: 432 LGCLSQLIWARGMGLPLERPKSHSTDGLIKL 462
>At2g44350 [C] KOG2617 Citrate synthase
Length = 474
Score = 387 bits (993), Expect = e-107
Identities = 202/454 (44%), Positives = 288/454 (62%), Gaps = 23/454 (5%)
Query: 19 LNLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTLDPNEG 78
L+LK+ + ++IP++++ L +K V++G+IT+ VI GMRG + WE++ LDP EG
Sbjct: 39 LDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGLLWETSLLDPEEG 98
Query: 79 IRFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELAERGAK 138
IRF G +I ECQK+LP A E LPE +LWLL+TG+VPS+EQV L+++LA R A
Sbjct: 99 IRFRGLSIPECQKVLPTAQSG---AEPLPEGLLWLLLTGKVPSKEQVEALSKDLANRAA- 154
Query: 139 LPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVYEDVLNL 198
+P + + +LP HPMTQ A + ++ S F + Y+ G I K +WE YED LNL
Sbjct: 155 VPDYVYNAIDALPSTAHPMTQFASGVMALQVQSEFQKAYENG-IHKSKFWEPTYEDCLNL 213
Query: 199 IAALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQERSNDF 258
IA +P + +Y + +G+ + + D+ N + +LG
Sbjct: 214 IARVPVVAAYVYRRMYKNGDSIPS-DKSLDYGANFSHMLGFD--------------DEKV 258
Query: 259 VNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRF 318
L+RLY IH DHEGGNVSAHT HLVGSALSDPYLS+++ + GLAGPLHGLA QEV+ +
Sbjct: 259 KELMRLYITIHSDHEGGNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLW 318
Query: 319 LVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAEKRPKEF 378
+ + ++ + +Q++EY+WK LNS +VIPGYGH VLR DPR+ FA K
Sbjct: 319 IKSVVEECGEDISKEQLKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFA---LKHL 375
Query: 379 KSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTVIFGCSR 438
D QL+ +L ++ P VL E GK KNP+PNVD+ SG+L HYG+ + ++TV+FG SR
Sbjct: 376 PDDPLFQLVSKLYEVVPPVLTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSR 435
Query: 439 AMGPLSQLVWDRILGLPIERPKSIDLNTIKKICK 472
++G SQL+WDR LGL +ERPKS+ ++ ++ CK
Sbjct: 436 SLGICSQLIWDRALGLALERPKSVTMDWLEAHCK 469
>At3g60100 [C] KOG2617 Citrate synthase
Length = 433
Score = 381 bits (979), Expect = e-105
Identities = 199/454 (43%), Positives = 290/454 (63%), Gaps = 27/454 (5%)
Query: 20 NLKAAIADVIPKRREELLHIKKNFSDVKVGDITIGSVINGMRGNQSMYWESTTLDPNEGI 79
+LK+ + ++IP++++ L +K V VG+IT+ V+ GMRG + WE++ LD +EGI
Sbjct: 5 DLKSQMQEIIPEQQDRLKKLKSEQGKVPVGNITVDMVLGGMRGMTGLLWETSLLDADEGI 64
Query: 80 RFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQELAERGAKL 139
RF G +I ECQK+LP A ++G+ E LPES+LWLL+TG+VP++EQ L+ ELA R A
Sbjct: 65 RFRGMSIPECQKILPSA--ESGE-EPLPESLLWLLLTGKVPTKEQANALSTELAHRAAV- 120
Query: 140 PPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYVYEDVLNLI 199
+ +LP HPMTQ A + ++ S F + Y++G I K YWE +ED LNLI
Sbjct: 121 -----PAIDALPSTAHPMTQFASGVMALQVQSEFQKAYEQGDISKSKYWEPTFEDALNLI 175
Query: 200 AALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHSLTQERSNDFV 259
A +P + +Y + DG + + D+ N + +LG DS M L
Sbjct: 176 ARVPVVASYVYRRMYKDGSIIP-LDDSLDYGANFSHMLGF---DSPQMKEL--------- 222
Query: 260 NLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFL 319
+RLY IH DHEGGNVSAH HLVGSALSDPYLS+++ + GLAGPLHGLA QEV+ ++
Sbjct: 223 --MRLYVTIHSDHEGGNVSAHAGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWI 280
Query: 320 VEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLNFAEKRPKEFK 379
+ ++ + +Q+++Y+WK LNS +V+PGYGH VLRK DPR+ FA K
Sbjct: 281 KLVVEECGESISKEQLKDYVWKTLNSGKVVPGYGHGVLRKTDPRYICQREFA---LKHLP 337
Query: 380 SDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLFFTVIFGCSRA 439
D QL+ +L ++ P +L E GK KNP+PNVD+ SG+L +YG+ + ++TV+FG SR+
Sbjct: 338 DDPLFQLVSKLYEVVPPILTELGKVKNPWPNVDAHSGVLLNYYGLTEARYYTVLFGVSRS 397
Query: 440 MGPLSQLVWDRILGLPIERPKSIDLNTIKKICKI 473
+G SQL+WDR LGLP+ERPKS++++ + ++
Sbjct: 398 LGICSQLIWDRALGLPLERPKSVNMDWLDNFTRL 431
>7299562 [C] KOG2617 Citrate synthase
Length = 407
Score = 340 bits (871), Expect = 4e-93
Identities = 183/413 (44%), Positives = 262/413 (63%), Gaps = 24/413 (5%)
Query: 60 MRGNQSMYWESTTLDPNEGIRFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEV 119
MRG ++ E+++LD N+GI + GK + + LP E G E PE +LL +G +
Sbjct: 1 MRGLPLLFCETSSLDKNKGIYYRGKLLKDVCAKLPRVQE--GTQEGTPEGCFFLLTSGSM 58
Query: 120 PSEEQVRKLTQELAERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQE 179
P++++ +++T E +RG+ +P + +++ S+ + +HPM QL A A +N S F E Y +
Sbjct: 59 PTKKEAQEVTNEWLKRGS-VPRYCLRMIDSMDKRVHPMAQLCAASACLNPQSQFVEAYTK 117
Query: 180 GSIGKMDYWEYVYEDVLNLIAALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGM 239
G+ + DYW+Y YED +NLIA LP + IYSN+ DGE N E+DWS N +LG+
Sbjct: 118 GA-RRADYWKYSYEDSMNLIAMLPTVAAAIYSNVFRDGEGSREVNYEEDWSGNFCRMLGL 176
Query: 240 TVSDSVNMHSLTQERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSG 299
DFV+L+RLY +H DHE GNVSAH HLVG+ALSDP+LS+S+
Sbjct: 177 P--------------EKDFVDLMRLYMILHADHESGNVSAHACHLVGTALSDPFLSFSAS 222
Query: 300 IMGLAGPLHGLAAQEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRK 359
+ GLAGPLHGLA QEV+ +L ++ K + + +++++++ L +VIPGYGHAVLR
Sbjct: 223 MCGLAGPLHGLANQEVLVWLTKLRKAIGDDPSDEELKKFIDDTLKGGQVIPGYGHAVLRD 282
Query: 360 PDPRFDAMLNFAEKRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILF 419
DPRF FA K K+ D V+L+ +L +I P+VLK+ K NPYPNVD+ SG+L
Sbjct: 283 TDPRFVLQNEFAMKHCKD---DPGVKLVTRLWKIIPEVLKKLNKVANPYPNVDAHSGVLL 339
Query: 420 YHYGIDQLLFFTVIFGCSRAMGPLSQLVWDRILGLPIERPKSIDLNTIKKICK 472
HY + +L F+TV+FG SRA+G LSQL+W R LG PIERPKS + +ICK
Sbjct: 340 QHYCLKELKFYTVLFGVSRALGVLSQLIWSRALGAPIERPKSF---SSIEICK 389
>At2g42790 [C] KOG2617 Citrate synthase
Length = 509
Score = 99.8 bits (247), Expect = 8e-21
Identities = 104/398 (26%), Positives = 173/398 (43%), Gaps = 48/398 (12%)
Query: 73 LDPNEGI-RFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQE 131
+D +EGI R+ G I E + FL + +LLM G +PSE Q+
Sbjct: 107 IDGDEGILRYRGYPIEEMAE----------NSTFL--EVAYLLMYGNLPSESQLSDWEFA 154
Query: 132 LAERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYV 191
+++ A +P ++ S+P D HPM L A++++ SIF G+ Y
Sbjct: 155 VSQHSA-VPQGVLDIIQSMPHDAHPMGVLVSAMSAL---SIFHPDANPALRGQDIYDSKQ 210
Query: 192 YED--VLNLIAALPKITGKIYSNIVNDGE--PLGHYNVEKDWSYNIASLLGMTVSDSVNM 247
D ++ +I P I Y + P G+ ++ Y + SL + + +
Sbjct: 211 VRDKQIIRIIGKAPTIAAAAYLRMAGRPPVLPSGNLPYADNFLYMLDSLGNRSYKPNPRL 270
Query: 248 HSLTQERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPL 307
++ + +H +HE +A HL S + D Y + + + L GPL
Sbjct: 271 -----------ARVLDILFILHAEHEMNCSTAAARHLASSGV-DVYTAVAGAVGALYGPL 318
Query: 308 HGLAAQEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAM 367
HG A + V++ L E + +VEN+ E++ V N R + G+GH V + DPR +
Sbjct: 319 HGGANEAVLKMLSE----IGTVENIP---EFIEGVKNRKRKMSGFGHRVYKNYDPRAKVI 371
Query: 368 LNFAEKRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQL 427
N A++ D +++ L + A + ++ + YPNVD SG+++ G
Sbjct: 372 KNLADEVFSIVGKDPLIEVAVALEKAA--LSDDYFVKRKLYPNVDFYSGLIYRAMGFPP- 428
Query: 428 LFFTVIFGCSRAMGPLSQLVWDRILGLP---IERPKSI 462
FFTV+F R G LS W L P I RP+ +
Sbjct: 429 EFFTVLFAIPRMAGYLSH--WKESLDDPDTKIMRPQQV 464
>At3g58750 [C] KOG2617 Citrate synthase
Length = 514
Score = 93.6 bits (231), Expect = 6e-19
Identities = 98/389 (25%), Positives = 168/389 (42%), Gaps = 41/389 (10%)
Query: 73 LDPNEGI-RFHGKTIAECQKLLPGAPEDNGKGEFLPESMLWLLMTGEVPSEEQVRKLTQE 131
+D +EGI R+ G I E + F+ + +LLM G +PS+ Q+
Sbjct: 112 IDGDEGILRYRGYPIEELAE----------SSTFI--EVAYLLMYGNLPSQSQLADWEFT 159
Query: 132 LAERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGSIFAEKYQEGSIGKMDYWEYV 191
+++ A +P ++ S+P D HPM L A++++ SIF G+ Y
Sbjct: 160 VSQHSA-VPQGVLDIIQSMPHDAHPMGVLVSAMSAL---SIFHPDANPALSGQDIYKSKQ 215
Query: 192 YED--VLNLIAALPKITGKIYSNIVNDGEPLGHYNVEKDWSYNIASLLGMTVSDSVNMHS 249
D ++ ++ P I Y G P + +S N +L +M +
Sbjct: 216 VRDKQIVRILGKAPTIAAAAYLRTA--GRPPVLPSANLSYSENFLYMLD-------SMGN 266
Query: 250 LTQERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHG 309
+ + + ++ + +H +HE +A HL S + D Y + + + L GPLHG
Sbjct: 267 RSYKPNPRLARVLDILFILHAEHEMNCSTAAARHLASSGV-DVYTACAGAVGALYGPLHG 325
Query: 310 LAAQEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSRVIPGYGHAVLRKPDPRFDAMLN 369
A + V++ L E + + EN + +++ V N R + G+GH V + DPR +
Sbjct: 326 GANEAVLKMLAE----IGTAEN---IPDFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIKK 378
Query: 370 FAEKRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNPYPNVDSASGILFYHYGIDQLLF 429
A++ D +++ L + A + E+ + YPNVD SG+++ G F
Sbjct: 379 LADEVFSIVGRDPLIEVAVALEKAA--LSDEYFVKRKLYPNVDFYSGLIYRAMGFPP-EF 435
Query: 430 FTVIFGCSRAMGPLSQLVWDRILGLPIER 458
FTV+F R G LS W L P R
Sbjct: 436 FTVLFAVPRMAGYLSH--WRESLDDPDTR 462
>At3g58740 [C] KOG2617 Citrate synthase
Length = 480
Score = 85.1 bits (209), Expect = 2e-16
Identities = 88/358 (24%), Positives = 155/358 (42%), Gaps = 39/358 (10%)
Query: 112 WLLMTGEVPSEEQVRKLTQELAERGAKLPPHTEKLLTSLPRDMHPMTQLAIALASMNKGS 171
+LL+ G +PS+ Q+ +++ A +P ++ S+P D+HP+ L A++++ S
Sbjct: 137 YLLIYGNLPSQRQLADWEFAISQNSA-VPQGVLDMIQSMPNDVHPVGALVTAMSAL---S 192
Query: 172 IFAEKYQEGSIGKMDYWEYVYED--VLNLIAALPKITGKIYSNIVNDG--EPLGHYNVEK 227
IF +G Y D ++ ++ P I Y +PL + + +
Sbjct: 193 IFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSE 252
Query: 228 DWSYNIASLLGMTVSDSVNMHSLTQERSNDFVNLVRLYCGIHVDHEGGNVSAHTTHLVGS 287
++ Y + S M + + + ++ + + +HE +A HL S
Sbjct: 253 NFLYMVES-----------MGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSS 301
Query: 288 ALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLVEMEKDVDSVENVKQVEEYLWKVLNSSR 347
D Y + S G+ + GPLHG A + + L E + +VEN+ E++ V N R
Sbjct: 302 G-GDVYTAVSGGVGAIYGPLHGGAVEATINMLSE----IGTVENIP---EFIESVKNKKR 353
Query: 348 VIPGYGHAVLRKPDPRFDAMLNFAEKRPKEFKSDAKVQLMKQLSQIAPKVLKEHGKTKNP 407
+ G+GH + + DPR + A++ D V++ L + A + E+ +
Sbjct: 354 RLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAA--LSDEYFVKRKL 411
Query: 408 YPNVDSASGILFYHYGIDQLLFFTVIFGCSRAMGPLSQLVWDRILGLP---IERPKSI 462
YPNVD SG++ GI FT + SR G LS W L P I RP+ +
Sbjct: 412 YPNVDFYSGLINRAMGIPS--SFTAV---SRIAGYLSH--WRESLDDPDTKIMRPQQV 462
>Hs17434182 [C] KOG2617 Citrate synthase
Length = 264
Score = 77.0 bits (188), Expect = 6e-14
Identities = 37/83 (44%), Positives = 56/83 (66%)
Query: 268 IHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLVEMEKDVD 327
IH DHE N+SAH HL GS LSDP L +++ + GLA PLHGLA QEV+ +L +++K+V
Sbjct: 176 IHSDHEHSNISAHARHLAGSTLSDPSLPFAAAMNGLAVPLHGLANQEVLVWLTQLQKEVG 235
Query: 328 SVENVKQVEEYLWKVLNSSRVIP 350
+ +++++Y + SR+ P
Sbjct: 236 KDVSDEKLQDYTELEMGCSRLWP 258
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,580,598
Number of Sequences: 60738
Number of extensions: 1300668
Number of successful extensions: 3613
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3538
Number of HSP's gapped (non-prelim): 17
length of query: 473
length of database: 30,389,216
effective HSP length: 110
effective length of query: 363
effective length of database: 23,708,036
effective search space: 8606017068
effective search space used: 8606017068
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)