ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3642 good B KOG2696 Chromatin structure and dynamics Histone acetyltransferase type b catalytic subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3642 1266038 1264869 -390
(390 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL001w [B] KOG2696 Histone acetyltransferase type b catalytic s... 385 e-107
Hs4504341 [B] KOG2696 Histone acetyltransferase type b catalytic... 150 4e-36
7296673 [B] KOG2696 Histone acetyltransferase type b catalytic s... 137 3e-32
SPAC23C4.01 [B] KOG2696 Histone acetyltransferase type b catalyt... 127 4e-29
CE03495 [B] KOG2696 Histone acetyltransferase type b catalytic s... 115 1e-25
At5g56740 [B] KOG2696 Histone acetyltransferase type b catalytic... 106 5e-23
SPAC139.06 [B] KOG2696 Histone acetyltransferase type b catalyti... 72 2e-12
>YPL001w [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 374
Score = 385 bits (990), Expect = e-107
Identities = 190/370 (51%), Positives = 264/370 (71%), Gaps = 4/370 (1%)
Query: 2 AVDLRPETWTVSSNEALNLSLVDENGAVNFKPTFTYPIYGDSEQIFGYKNLQIFLAFDSI 61
A D +PETWT S+NEAL +S+V EN AV F P FTYPIYGDSE+I+GYK+L I LAFDS+
Sbjct: 3 ANDFKPETWTSSANEALRVSIVGEN-AVQFSPLFTYPIYGDSEKIYGYKDLIIHLAFDSV 61
Query: 62 TFKPFVNVKYDAKLNNE-IEDVQKLLLDKLPEDDVIIKDEEAWIKTFTKEQETFALPEKD 120
TFKP+VNVKY AKL ++ I DV+K LL LP+DDVI++DE W+ F +E++T L +
Sbjct: 62 TFKPYVNVKYSAKLGDDNIVDVEKKLLSFLPKDDVIVRDEAKWVDCFAEERKTHNLSDVF 121
Query: 121 KLVEEYEIGDQEFVIYRVSLQDPAIKMLHKRMQIFTLLFIESASYIDENDSSWEIFIVFN 180
+ V EY + +EFV+Y+ SL D + +H+R+QIF+LLFIE+A+YIDE D SW+I+ + N
Sbjct: 122 EKVSEYSLNGEEFVVYKSSLVDDFARRMHRRVQIFSLLFIEAANYIDETDPSWQIYWLLN 181
Query: 181 KNSKKCIGYTTTYQFWKYLGAQSFDSSKADEQKCRAKISQFLIMPPYQGHGHGKRLYQAI 240
K +K+ IG+ TTY++W YLGA+SFD ++K RAKISQFLI PPYQ GHG LY+AI
Sbjct: 182 KKTKELIGFVTTYKYWHYLGAKSFDED--IDKKFRAKISQFLIFPPYQNKGHGSCLYEAI 239
Query: 241 VKQWMNDLSVVEITVEDPNESFDDLRDRCDFERVINKNSLADCPNELPINIDWITKKQAQ 300
++ W+ D S+ EITVEDPNE+FDDLRDR D +R+ A ++ +++ +
Sbjct: 240 IQSWLEDKSITEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLSDEFLESSRKS 299
Query: 301 LKLEKRQFMRILEMFLLYQKSPNYRLQLKKRIYEKNFEALMDMDESLKKDKLQTAFQSLT 360
LKLE+RQF R++EM LL SP++ L++K R+Y KN++AL D ++ LQ +F +
Sbjct: 300 LKLEERQFNRLVEMLLLLNNSPSFELKVKNRLYIKNYDALDQTDPEKAREALQNSFILVK 359
Query: 361 EDYNRILSKV 370
+DY RI+ +
Sbjct: 360 DDYRRIIESI 369
>Hs4504341 [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 419
Score = 150 bits (378), Expect = 4e-36
Identities = 117/426 (27%), Positives = 199/426 (46%), Gaps = 81/426 (19%)
Query: 2 AVDLRPETWTVSSNEALNLSLVD-----ENGAVNFKPTFTYPIYGDSEQIFGYKNLQIFL 56
AV+ + + ++N A+ L LV EN F P +T+ ++GD E FGYK L+I L
Sbjct: 17 AVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILL 76
Query: 57 AFDSITFKPFVNVKYDAKLNNEIEDVQKLLLDKLPEDDVIIKDEEAWIKTF-TKEQETFA 115
+ + + V+Y +K++ + V+ DDV K + F T + +
Sbjct: 77 YYIAGSLSTMFRVEYASKVDENFDCVEA--------DDVEGKIRQIIPPGFCTNTNDFLS 128
Query: 116 LPEKD-------KLVEEYEI----GDQEFV--IYRVSLQDPAIKMLHKRMQIFTLLFIES 162
L EK+ L+ Y + G + F IY+ + + H+R+Q F + FIE+
Sbjct: 129 LLEKEVDFKPFGTLLHTYSVLSPTGGENFTFQIYKADMTCRGFREYHERLQTFLMWFIET 188
Query: 163 ASYIDENDSSWEIFIVFNKNSKK------CIGYTTTYQFWKYLGAQSFDSSKADEQKCRA 216
AS+ID +D W F+VF K +K +GY T Y ++ Y K R
Sbjct: 189 ASFIDVDDERWHYFLVFEKYNKDGATLFATVGYMTVYNYYVY------------PDKTRP 236
Query: 217 KISQFLIMPPYQGHGHGKRLYQAIVKQWMNDLSVVEITVEDPNESFDDLRD-----RCDF 271
++SQ LI+ P+QG GHG +L + + + + +V++IT EDP++S+ LRD C
Sbjct: 237 RVSQMLILTPFQGQGHGAQLLETVHRYYTEFPTVLDITAEDPSKSYVKLRDFVLVKLCQD 296
Query: 272 ERVINKNSLADCPNELPINIDWITKKQAQLKLEKRQFMRILEMFLLY-------QKSPNY 324
++ L NE D + Q + K+ K+ R+ E+ L ++ +Y
Sbjct: 297 LPCFSREKLMQGFNE-----DMAIEAQQKFKINKQHARRVYEILRLLVTDMSDAEQYRSY 351
Query: 325 RLQLKKRI---YEKNFEALMDM----------------DESLKKDKLQTAFQSLTEDYNR 365
RL +K+R+ Y+K L M + S++ ++L+ +FQ L EDY R
Sbjct: 352 RLDIKRRLISPYKKKQRDLAKMRKCLRPEELTNQMNQIEISMQHEQLEESFQELVEDYRR 411
Query: 366 ILSKVA 371
++ ++A
Sbjct: 412 VIERLA 417
>7296673 [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 405
Score = 137 bits (345), Expect = 3e-32
Identities = 98/377 (25%), Positives = 180/377 (46%), Gaps = 47/377 (12%)
Query: 8 ETWTVSSNEALNLSLVDE-----NGAVNFKPTFTYPIYGDSEQIFGYKNLQIFLAFDSIT 62
+ + + + E ++ L+ + N A+ F P + I+G++E IFGY++L + + + +
Sbjct: 8 QDFVIDALEVVDFKLIRDKADINNDALTFHPAMAHQIFGETETIFGYQDLHVRVMYTAGP 67
Query: 63 FKPFVNVKYDAKLNN------EIEDVQKLLLDKLPEDDVIIKDEEAWIKTFTKEQETFAL 116
++ V Y ++N + +DV + LP+ I +E ++KT K +
Sbjct: 68 LHIYLGVDYGKRVNEISGGEIKADDVVSTIAQSLPDGCYFINLDE-FLKTLDKADKFQPF 126
Query: 117 PEKDKLVEEY-----EIGDQEFVIYRVSLQDPAIKMLHKRMQIFTLLFIESASYIDENDS 171
EK + EY + ++ F IY+ + + R+Q F L F+++ASYID +D
Sbjct: 127 GEK---ISEYRRVSDDGSERLFEIYQCEYKSSSFLKFFARLQTFILWFVDAASYIDTDDP 183
Query: 172 SWEIFIVFNKNSKK-------CIGYTTTYQFWKYLGAQSFDSSKADEQKCRAKISQFLIM 224
W F+ + K GYTT Y+++ Y Q R +ISQ LI+
Sbjct: 184 QWCYFLSYEKYKNNDGQWQYATAGYTTVYEYYAY------------PQNKRPRISQMLIL 231
Query: 225 PPYQGHGHGKRLYQAIVKQWMNDLSVVEITVEDPNESFDDLRDRCDFERVINKNSLADCP 284
PP+Q G +L ++I + + + +VV+ITVEDP+E F LR+ D + S A
Sbjct: 232 PPFQKLGLATQLVESIYRFYQSQKNVVDITVEDPSEDFQRLRNFVDARSCMKLKSFAPGE 291
Query: 285 NELPINIDWITKKQAQLKLEKRQFMRILEMFLLYQKSPN-------YRLQLKKRIYEKNF 337
N + + + + LKL Q ++ E+ L+ + YRL++KKR+ +
Sbjct: 292 IVKGFNKEMVREAREALKLNPLQVRKVYELLRLFYTNVKDEKEYRPYRLEVKKRLNAVYY 351
Query: 338 EALMDMDESLKKDKLQT 354
+ L D+ + +++ K+ T
Sbjct: 352 KQLKDL-KKMERFKMDT 367
>SPAC23C4.01 [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 244
Score = 127 bits (318), Expect = 4e-29
Identities = 66/192 (34%), Positives = 115/192 (59%), Gaps = 19/192 (9%)
Query: 188 GYTTTYQFWKYLGAQSFDSSKADEQKCRAKISQFLIMPPYQGHGHGKRLYQAIVKQWMND 247
GY T Y+++K+ K RA+ISQF+I+PP+Q GHG +LY AIV ++ +
Sbjct: 44 GYCTVYKYYKW--------DKLIHDGIRARISQFVILPPFQHQGHGSQLYNAIVSTFLKN 95
Query: 248 LSVVEITVEDPNESFDDLRDRCDFERVINKNSLADCPNELPINIDWITKKQAQLKLEKRQ 307
+++ TVED +E+FD LRD CD++R+++ ++ ++ WI K A+ KL +RQ
Sbjct: 96 PKILDFTVEDASEAFDSLRDHCDYKRLLSMGIFSEPDFHPSLSRQWINSKIAETKLTQRQ 155
Query: 308 FMRILE---------MFLLYQKSPNYRLQLKKRIYEKNFEALMDMDESLKKDKLQTAFQS 358
F R E + LL +KS RL +K+RI+ +N + L+ +D+S + +K+ A+++
Sbjct: 156 FSRCCELAFTTKLKKLSLLERKS--VRLGIKERIFRQNLDVLLQLDKSERIEKIHNAYEN 213
Query: 359 LTEDYNRILSKV 370
++Y +I+ K+
Sbjct: 214 QFDEYKQIVKKL 225
>CE03495 [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 541
Score = 115 bits (287), Expect = 1e-25
Identities = 86/377 (22%), Positives = 174/377 (45%), Gaps = 56/377 (14%)
Query: 28 AVNFKPTFTYPIYGDSEQIFGYKNLQIFLAFDSITFKPFVNVKYDAKLNNEIEDVQKLLL 87
A ++P Y +GD E IFGY++L++ + + T ++NV Y +K NE ++
Sbjct: 167 APRYEPEMVYQHFGDEETIFGYEDLEVTIHHTAQTLYSYINVSYSSKAKNENGLEADDVI 226
Query: 88 DKLPEDD----VIIKDEEAWIKTFTKEQETFALPEKDKLVEEYEIGDQEFVIYRVSLQDP 143
DKL D V++ +E + + K+++ E +V ++E+ + + +Y+V+ Q
Sbjct: 227 DKLVHPDVRPNVLVSGKEEFQQKLIKQKDFKPFGE---MVHKFELKGKSYEVYKVAEQTE 283
Query: 144 AIKMLHKRMQIFTLLFIESASYIDENDSSWEIFIVFNK---------NSKKCIGYTTTYQ 194
+ +R+Q + FIE S D + +W + ++ + GY T ++
Sbjct: 284 EFNLFLERIQTLGMFFIECCSLTDNTEDNWLHYFIYERCDTGEGDGSTVANVAGYATLFK 343
Query: 195 FWKYLGAQSFDSSKADEQKCRAKISQFLIMPPYQGHGHGKRLYQAIVKQWMNDLSVVEIT 254
F+ Y+ + R +I+Q L++P Y+ G G ++ ++ V ++T
Sbjct: 344 FYNYI------------DRIRPRIAQMLLLPQYRKSGIGASFMESFLRDLRASPEVFDVT 391
Query: 255 VEDPNESFDDLRDRCDFERVINKNSLADCPNELPINIDWITKKQA--QLKLEKRQFMRIL 312
VE P + F LRD D + A P L ++ A +LK+ ++Q R+
Sbjct: 392 VESPGDQFVSLRDYVDCVNCMTLREFA--PENLKRGYSDKMRQAALEKLKISRQQARRVY 449
Query: 313 EMFLLYQKSPN---------YRLQLKKRIY---EKNFEALMDMDESLKKDKL-------- 352
E +L ++ N R+ +K+R+Y +K+ + ++ +L D+L
Sbjct: 450 E--ILRYRATNKKDKEELKAQRIDVKRRLYAPMKKSDQDWKRLNLALTPDELRQAACGQM 507
Query: 353 --QTAFQSLTEDYNRIL 367
+T F +L+++Y+R++
Sbjct: 508 DEETKFSTLSQNYDRLM 524
>At5g56740 [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 467
Score = 106 bits (265), Expect = 5e-23
Identities = 84/363 (23%), Positives = 162/363 (44%), Gaps = 59/363 (16%)
Query: 3 VDLRPETWTVSSNEALNLSLV------DENGAVNFKPTFTYPIYGDSEQIFGYKNLQIFL 56
V P V +NE + + LV D + + KP + +I+GY+ L+I +
Sbjct: 21 VGFSPADTGVEANECIKIYLVSSKEEVDSSDISSVKPVDLNDFFDGDGKIYGYQGLKINV 80
Query: 57 AFDSITFKPFVNVKYDAKLNNE--IEDVQKLLLDKLPEDDVIIKDEEAWIKTFTKEQ--- 111
+SI+ + ++ Y + +N + I D++ L + E V KDE +++TF+ ++
Sbjct: 81 WINSISLHSYADITYQSTINGDKGITDLKSALQNIFAETIVDTKDE--FLQTFSTQRDFI 138
Query: 112 -------ETFALPEKDKLVEEYEIGDQEFVIYRVSLQDPAIKMLHKRMQIFTLLFIESAS 164
E D + E+ + + R+ + P +L+ R+ LLF++ ++
Sbjct: 139 RNMVSNGEVMHAGATDGSSKNAEVVPSDPQVIRMEIGSPNAGLLYSRLVPLVLLFVDGSN 198
Query: 165 YIDENDSSWEIFIVFNKNSKK------CIGYTTTYQFWKYLGAQSFDSSKADEQKCRAKI 218
ID D W ++++ K +K +G+T Y+F++Y + R ++
Sbjct: 199 PIDVTDPDWHLYLLIQKKEEKEDPLYRIVGFTAIYKFYRY------------PDRLRMRL 246
Query: 219 SQFLIMPPYQGHGHGKRLYQAIVKQWMNDLSVVEITVEDPNESFDDLRDRCDFERV---- 274
SQ L++P +QG G G L + + + + +V ++TVE+P+E F +R D R+
Sbjct: 247 SQILVLPSFQGKGLGSYLMEVVNNVAITE-NVYDLTVEEPSEKFQHIRTCIDINRLRSFD 305
Query: 275 ------------INKNSL---ADCPNELPINIDWITKKQAQLKLEKRQFMRILEMFLLYQ 319
+ K L A P P ++ I K + LK+ K+QF++ E+ +
Sbjct: 306 PIKPDIDSAVQTLTKGKLSKKAQIPRFTP-PLNAIEKVRESLKINKKQFLKCWEILIYLA 364
Query: 320 KSP 322
P
Sbjct: 365 LDP 367
>SPAC139.06 [B] KOG2696 Histone acetyltransferase type b catalytic subunit
Length = 166
Score = 71.6 bits (174), Expect = 2e-12
Identities = 46/179 (25%), Positives = 86/179 (47%), Gaps = 25/179 (13%)
Query: 8 ETWTVSSNEALNLSLVDENGAVN--FKPTFTYPIYGDSEQIFGYKNLQIFLAFDSITFKP 65
+ W ++NE + + V+E + + P+ TY I+GD+E I+GYK+L + + ++ P
Sbjct: 5 DEWVHNANECIEIVQVNEKHEKDCQYHPSNTYAIFGDAEVIYGYKDLNVTITYECPLMVP 64
Query: 66 FVNVKYDAKLNNEIEDVQKLLLDKLPEDDVIIKDEEAWIKTFTK------EQETFALPEK 119
+ + Y +L P+ V D E + T+ K E +F +
Sbjct: 65 KLEISYSERL--------------APDSGVEPTDIEGTLNTYLKDRSIKVEGNSFDVHSA 110
Query: 120 DKLVEEYEIGDQEFVIYRVSLQDPAIKMLHKRMQIFTLLFIESASYIDENDSSWEIFIV 178
+ + Y + F I + ++ + + M H +QIF+L FIE S+ID ND W ++++
Sbjct: 111 NS-IHNYSFNGKTFKILQATVLEASEIMQH--LQIFSLFFIEGGSFIDLNDPRWMVYLL 166
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,005,635
Number of Sequences: 60738
Number of extensions: 1062108
Number of successful extensions: 3046
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3022
Number of HSP's gapped (non-prelim): 7
length of query: 390
length of database: 30,389,216
effective HSP length: 108
effective length of query: 282
effective length of database: 23,829,512
effective search space: 6719922384
effective search space used: 6719922384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)