ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3754 good R KOG0254 General function prediction only Predicted transporter (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3754 1302073 1303989 639
(639 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHL040c [R] KOG0254 Predicted transporter (major facilitator sup... 593 e-169
YHL047c [R] KOG0254 Predicted transporter (major facilitator sup... 575 e-164
YCL073c [R] KOG0254 Predicted transporter (major facilitator sup... 481 e-135
YKR106w [R] KOG0254 Predicted transporter (major facilitator sup... 479 e-135
YEL065w [R] KOG0254 Predicted transporter (major facilitator sup... 369 e-102
YOL158c [R] KOG0254 Predicted transporter (major facilitator sup... 226 1e-58
SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator ... 214 4e-55
SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator ... 169 2e-41
SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator... 166 1e-40
YPR198w [R] KOG0254 Predicted transporter (major facilitator sup... 66 2e-10
SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitato... 61 6e-09
>YHL040c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 627
Score = 593 bits (1528), Expect = e-169
Identities = 279/588 (47%), Positives = 391/588 (66%), Gaps = 6/588 (1%)
Query: 41 ENHKQELLDEYGVP------DKLRANRSLVIRKMEIMRKQYTSVFAICVFLFTAFLAGVG 94
E H D YG+P + LR NRSL+I++ EI+ Y + + L +AF+ G G
Sbjct: 28 ETHNDSNSDSYGLPQLSEKYNALRQNRSLIIQQTEIIGSAYNKWYLQAILLLSAFICGYG 87
Query: 95 TDLNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIISAGALTVYARLSDVFGRIRLYLSAM 154
L+ +R YT YAT+SY HSLLSTI V+++++SA + +YARLSDVFGR+ L++SA+
Sbjct: 88 YGLDGNIRYIYTGYATSSYSEHSLLSTINVINAVVSAASQIIYARLSDVFGRLYLFISAV 147
Query: 155 LFFVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQVMMFIIMSDFSSLKWRLFFTFAPTWP 214
+ +VVGTIIQSQA +VQ+YAAG +FY+ G G+ +++ II+SDFSSLKWRL + F PTWP
Sbjct: 148 ILYVVGTIIQSQAYDVQRYAAGAIFYNAGYVGVILILLIILSDFSSLKWRLLYQFVPTWP 207
Query: 215 NLFIPWITGSIVDRLDPVERWSWGIGMWAFIYPLSSVPFVAYLLLVRYKASKTEEWKMLS 274
+ WI G+I R +PV WSW +GMWAFI+PLS VP V +L ++++A KT EW L
Sbjct: 208 FIINTWIAGNITSRANPVVNWSWDVGMWAFIFPLSCVPIVLCMLHMQWRARKTPEWHALK 267
Query: 275 SEKTYYETHGIIQTLVQLFWKXXXXXXXXXXXXXXCILVPLTLAGGVSSQWSNGKILGPF 334
+K+YY+ HG I+ L QLFW CILVPLTLAGGV + W++ +++GPF
Sbjct: 268 GQKSYYQEHGFIKILKQLFWMLDVVGVLLMGCSLGCILVPLTLAGGVKTTWNDSRLIGPF 327
Query: 335 ILGFCLVPAFILWETKYARLPIAPFKMLKDRGIWSALIISMLAKTVYYLAAGYLLTILMV 394
+LGF L+P +WE ++AR PI P++++KDR +WS++ IS L +YY+AA YL T+++V
Sbjct: 328 VLGFVLIPILWIWEYRFARDPILPYRLVKDRAVWSSMGISFLIDFIYYMAADYLYTVMIV 387
Query: 395 AVNQSRGMAAVIMNVWSVVGCGFSPFFSYFVVRVRRLKPFIIIGCGIWMVSMGLLYYYRS 454
AVN+S A I + S V SPFF+ V R RLKPFI+ GC +WMV+MGLLY++R
Sbjct: 388 AVNESVKSATRIATLSSFVSTVASPFFALLVTRCTRLKPFIMFGCALWMVAMGLLYHFRG 447
Query: 455 GEHSKGGIIGAMVLWGLGSTMITRTTVISSQSITAHENMATITAIMLXXXXXXXXXXXXX 514
G S GIIGA+ +WG+G+T+ T +S QS +HENMAT+TA+
Sbjct: 448 GSQSHSGIIGALCVWGVGTTLFTYPVTVSVQSAVSHENMATVTALNYTLYRIGSAVGSAV 507
Query: 515 XXXXWTQTLYAKLVETIGDPEIAKKVYQSPLSAIRVYAWGTPTRDAIVEAYRHVQRFEVL 574
WTQTLY ++++ +GD +A Y+SP + I Y WGTP R+A++ AY++VQR E +
Sbjct: 508 SGAIWTQTLYKQILKRMGDVALATTAYESPYTFIETYTWGTPQRNALMNAYKYVQRLETI 567
Query: 575 VAMILVIPLFIASLCLRDPELTDEVAHTDIKDGEFIAVDGNDAIANWF 622
VA++ +PL SLCLRDP+LTD VA I+DGE++ ND I +WF
Sbjct: 568 VALVFCVPLIAFSLCLRDPKLTDTVAVEYIEDGEYVDTKDNDPILDWF 615
>YHL047c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 637
Score = 575 bits (1481), Expect = e-164
Identities = 275/608 (45%), Positives = 392/608 (64%), Gaps = 4/608 (0%)
Query: 22 DNNEDSFPNANKE---NLTFAEENHKQELLDEYGVPDKLRANRSLVIRKMEIMRKQYTSV 78
DN N E N +E + + DKL+ +SL+IRK E+M K+Y +
Sbjct: 7 DNRSSQTKRKNTEKNCNELMVDEKMDDDSSPRDEMKDKLKGTKSLIIRKSELMAKKYDTW 66
Query: 79 FAICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIISAGALTVYA 138
+FLF+AF+ L+S +R Y TYA NSY +HSL+ST+ V+ +ISA + ++
Sbjct: 67 QLKAIFLFSAFICTFAYGLDSSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFG 126
Query: 139 RLSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQVMMFIIMSDF 198
LSD+FGR+ L+L +++ ++VGTIIQSQA +VQ+YAAG VFY +G G+ + + +++SD
Sbjct: 127 GLSDIFGRLTLFLVSIVLYIVGTIIQSQAYDVQRYAAGAVFYYVGLVGVMLQVVLMLSDN 186
Query: 199 SSLKWRLFFTFAPTWPNLFIPWITGSIVDRLDPVERWSWGIGMWAFIYPLSSVPFVAYLL 258
SSLKWRLF+T P+WP++ W++GS+V+ +P+E WSW I MWAFI+PL +P + +L
Sbjct: 187 SSLKWRLFYTLIPSWPSIITTWVSGSVVEAANPLENWSWNIAMWAFIFPLCCIPLILCML 246
Query: 259 LVRYKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXXXXXXXXXXXXXXCILVPLTLA 318
+R+K EWK L EK+YY+THG++Q LVQLFWK CILVPLTLA
Sbjct: 247 HMRWKVRNDVEWKELQDEKSYYQTHGLVQMLVQLFWKLDVVGVLLFTAGVGCILVPLTLA 306
Query: 319 GGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKMLKDRGIWSALIISMLAK 378
GGVS+ W N KI+GPF+LGF LVP FI WE++ A +P APFK+LKDRG+W+ L I
Sbjct: 307 GGVSTNWRNSKIIGPFVLGFVLVPGFIYWESRLALVPFAPFKLLKDRGVWAPLGIMFFIC 366
Query: 379 TVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYFVVRVRRLKPFIIIG 438
VY +AAGYL TIL+VAV++S A I+N++S V +PF V R RLK +II G
Sbjct: 367 FVYQMAAGYLYTILVVAVDESASSATRIINLYSFVTAVVAPFLGLIVTRSSRLKSYIIFG 426
Query: 439 CGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVISSQSITAHENMATITA 498
++ ++MGL Y YRSG+ + GGII MV+WGL S + T++S QS+T+HENMAT+TA
Sbjct: 427 GSLYFITMGLFYRYRSGQDADGGIIAGMVIWGLSSCLFDYPTIVSIQSVTSHENMATVTA 486
Query: 499 IMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGDPEIAKKVYQSPLSAIRVYAWGTPTR 558
+ WTQ+LY KL+ +GD ++A Y SPL+ I WGTP R
Sbjct: 487 LNYTVFRIGGAVAAAISGAIWTQSLYPKLLHYMGDADLATAAYGSPLTFILSNPWGTPVR 546
Query: 559 DAIVEAYRHVQRFEVLVAMILVIPLFIASLCLRDPELTDEVAHTDIKDGEFIAVDGNDAI 618
A+VEAYRHVQ++EV+VA++ P+F+ + C+RDP LT++ A + D E++ +D I
Sbjct: 547 SAMVEAYRHVQKYEVIVALVFSAPMFLLTFCVRDPRLTEDFAQ-KLPDREYVQTKEDDPI 605
Query: 619 ANWFSNKW 626
+W + ++
Sbjct: 606 NDWIAKRF 613
>YCL073c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 481 bits (1237), Expect = e-135
Identities = 228/554 (41%), Positives = 339/554 (61%)
Query: 65 IRKMEIMRKQYTSVFAICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGV 124
+++ EIM Q+ S+ + + TAF+ G G L+ LR+ YT YATNSY HSLLST+ V
Sbjct: 43 LKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV 102
Query: 125 VSSIISAGALTVYARLSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGT 184
+++++S G+ VY+RLSD FGR+RL+L A +F+++GTIIQSQA + YAAG+VFY+ G
Sbjct: 103 INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGY 162
Query: 185 AGIQVMMFIIMSDFSSLKWRLFFTFAPTWPNLFIPWITGSIVDRLDPVERWSWGIGMWAF 244
G +++ +I+SDFSSLKWR+F+ +A WP + IPWI+G+I+ +P + WSW I MWAF
Sbjct: 163 VGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF 222
Query: 245 IYPLSSVPFVAYLLLVRYKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXXXXXXXXX 304
IYPLS++P + +L ++YK+SKT EW+ L + T G+ + LV LFWK
Sbjct: 223 IYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLI 282
Query: 305 XXXXXCILVPLTLAGGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKMLKD 364
CILVPLTLA S +W N KI+ + G CL F+ WE K+A+ P+ PFK+L D
Sbjct: 283 TVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSD 342
Query: 365 RGIWSALIISMLAKTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYF 424
RGIW+ L ++ ++++ YL +L+V++ +S AA I+N+ V SPF+S
Sbjct: 343 RGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLL 402
Query: 425 VVRVRRLKPFIIIGCGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVISS 484
V + R+LK +I GC WMV MGL Y YR G S G+I A V+ GL + + + ++
Sbjct: 403 VAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVIL 462
Query: 485 QSITAHENMATITAIMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGDPEIAKKVYQSP 544
Q++T H MA IT I WTQT+ +L + +G+ +A+ Y SP
Sbjct: 463 QAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASP 522
Query: 545 LSAIRVYAWGTPTRDAIVEAYRHVQRFEVLVAMILVIPLFIASLCLRDPELTDEVAHTDI 604
+ I Y WG+P RDA+VE+YR+VQR + V + +P F ++ +RDPEL D+ H +
Sbjct: 523 YTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFAFTMFMRDPELIDKATHEEF 582
Query: 605 KDGEFIAVDGNDAI 618
+ + + + I
Sbjct: 583 TEDGLVVLPDEENI 596
>YKR106w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 479 bits (1232), Expect = e-135
Identities = 227/554 (40%), Positives = 339/554 (60%)
Query: 65 IRKMEIMRKQYTSVFAICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGV 124
+++ EIM Q+ S+ + + TAF+ G G L+ LR+ YT YATNSY HSLLST+ V
Sbjct: 43 LKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV 102
Query: 125 VSSIISAGALTVYARLSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGT 184
+++++S G+ VY+RLSD FGR+RL+L A +F+++GTIIQSQA + YAAG+VFY+ G
Sbjct: 103 INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGY 162
Query: 185 AGIQVMMFIIMSDFSSLKWRLFFTFAPTWPNLFIPWITGSIVDRLDPVERWSWGIGMWAF 244
G +++ +I+SDFSSLKWR+F+ +A WP + IPWI+G+I+ +P + WSW I MWAF
Sbjct: 163 VGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF 222
Query: 245 IYPLSSVPFVAYLLLVRYKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXXXXXXXXX 304
IYPLS++P + +L ++YK+SKT EW+ L + T G+ + LV LFWK
Sbjct: 223 IYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLI 282
Query: 305 XXXXXCILVPLTLAGGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKMLKD 364
CILVPLTLA S +W N KI+ + G CL F+ WE K+A+ P+ PFK+L D
Sbjct: 283 TVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSD 342
Query: 365 RGIWSALIISMLAKTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYF 424
RGIW+ L ++ ++++ YL +L+V++ +S AA I+N+ V SPF+S
Sbjct: 343 RGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLL 402
Query: 425 VVRVRRLKPFIIIGCGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVISS 484
V + R+LK +I GC WMV MGL Y YR G S G+I A V+ GL + + + ++
Sbjct: 403 VAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVIL 462
Query: 485 QSITAHENMATITAIMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGDPEIAKKVYQSP 544
Q++T H MA IT I WTQT+ +L + +G+ +A+ Y SP
Sbjct: 463 QAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASP 522
Query: 545 LSAIRVYAWGTPTRDAIVEAYRHVQRFEVLVAMILVIPLFIASLCLRDPELTDEVAHTDI 604
+ I Y WG+P RDA+VE+YR+VQR + V + +P F ++ +R+PEL D+ H +
Sbjct: 523 YTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTMFMRNPELIDKATHEEF 582
Query: 605 KDGEFIAVDGNDAI 618
+ + + + I
Sbjct: 583 TEDGLVVLPDEENI 596
>YEL065w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 628
Score = 369 bits (948), Expect = e-102
Identities = 190/538 (35%), Positives = 296/538 (54%), Gaps = 4/538 (0%)
Query: 65 IRKMEIMRKQYTSVFAICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGV 124
+ +EI + Y F+ FL L+ +R + YAT+SY HSLLST+
Sbjct: 54 VHNIEIYAEMYNRPIYRVALFFSLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNC 113
Query: 125 VSSIISAGALTVYARLSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGT 184
+ ++I+A +ARLSD+FGR + + +++F+ +GTII+SQA N+ ++A G FY LG
Sbjct: 114 IKTVIAAVGQIFFARLSDIFGRFSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGL 173
Query: 185 AGIQVMMFIIMSDFSSLKWRLFFTFAPTWPNLFIPWITGSIVDRLDPVERWSWGIGMWAF 244
GI +++ +I SDFS+L WRL F P P + WI+G++ +D W WGIGMWAF
Sbjct: 174 TGIILILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAID--ANWKWGIGMWAF 231
Query: 245 IYPLSSVPFVAYLLLVRYKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXXXXXXXXX 304
I PL+ +P +L +RY A K + ++ + + + FWK
Sbjct: 232 ILPLACIPLGICMLHMRYLARKHAKDRLKPEFEALNKLKWKSFCIDIAFWKLDIIGMLLI 291
Query: 305 XXXXXCILVPLTLAGGVSSQWSNGKILGPFILGFCLV-PAFILWETKYARLPIAPFKMLK 363
C+LVP TLAGG+ +W I+ P ++G+ +V P ++LWE KY+R P+ P+ +++
Sbjct: 292 TVFFGCVLVPFTLAGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLIQ 351
Query: 364 DRGIWSALIISMLAKTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSY 423
DRGI+ AL+I+ +Y+ Y+ T+L+VAV++S A I +++S V +
Sbjct: 352 DRGIFFALLIAFFINFNWYMQGDYMYTVLVVAVHESIKSATRITSLYSFVSVIVGTILGF 411
Query: 424 FVVRVRRLKPFIIIGCGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVIS 483
+++VRR KPFII G W+VS GLL +YR + GIIG++ L G G+ T T S
Sbjct: 412 ILIKVRRTKPFIIFGISCWIVSFGLLVHYRGDSGAHSGIIGSLCLLGFGAGSFTYVTQAS 471
Query: 484 SQ-SITAHENMATITAIMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGDPEIAKKVYQ 542
Q S H MA +T++ L WT L ++ + I DP +A + Y
Sbjct: 472 IQASAKTHARMAVVTSLYLATYNIGSAFGSSVSGAVWTNILPKEISKRISDPTLAAQAYG 531
Query: 543 SPLSAIRVYAWGTPTRDAIVEAYRHVQRFEVLVAMILVIPLFIASLCLRDPELTDEVA 600
SP + I Y WGTP R A+V +YR+VQ+ ++ ++ PL + LR+ +LTD +A
Sbjct: 532 SPFTFITTYTWGTPERIALVMSYRYVQKILCIIGLVFCFPLLGCAFMLRNHKLTDSIA 589
>YOL158c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 606
Score = 226 bits (575), Expect = 1e-58
Identities = 144/512 (28%), Positives = 244/512 (47%), Gaps = 17/512 (3%)
Query: 85 LFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIISAGALTVYARLSDVF 144
L FL G T L Q+ + TYA NS+ HS + +I V SI+++ YAR+SD F
Sbjct: 67 LVALFLQGYCTGLGGQISQSIQTYAANSFGKHSQVGSINTVKSIVASVVAVPYARISDRF 126
Query: 145 GRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQVMMFIIMSDFSSLKWR 204
GRI ++ A++ + +G II + AG V G +G +++ + D S L+ R
Sbjct: 127 GRIECWIFALVLYTIGEIISAATPTFSGLFAGIVIQQFGYSGFRLLATALTGDLSGLRDR 186
Query: 205 LFFTFAPTWPNLFIPWITGSIVDRLD---PVERWSWGIGMWAFIYPLSSVPFVAYLLLVR 261
F P + W++G+IV + +W WG G++ I P+S++ +L++
Sbjct: 187 TFAMNIFLIPVIINTWVSGNIVSSVAGNVAPYKWRWGYGIFCIIVPISTL-----ILVLP 241
Query: 262 YKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXX----XXXXXXXXXXXXCILVPLTL 317
Y ++ W+ + G QTL Q WK +L+PLT+
Sbjct: 242 YVYAQYISWRSGKLPPLKLKEKG--QTLRQTLWKFADDINLIGVILFTAFLVLVLLPLTI 299
Query: 318 AGGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKMLKDRGIWSALIISMLA 377
AGG +S+W G I+ ++G CL F++WE K+A+ P P L D I+ AL++ +
Sbjct: 300 AGGATSKWREGHIIAMIVVGGCLGFIFLIWELKFAKNPFIPRVYLGDPTIYVALLMEFVW 359
Query: 378 KTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYFVVRVRRLKPFIII 437
+ + YL+T+LMVA +S A I +++ + + + K F++
Sbjct: 360 RLGLQIELEYLVTVLMVAFGESTLSAQRIAQLYNFLQSCTNIVVGIMLHFYPHPKVFVVA 419
Query: 438 GCGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVISSQSITAHENMATIT 497
G + ++ MGLLY YR G+IGA ++ G+ MI + T H MAT+T
Sbjct: 420 GSLLGVIGMGLLYKYRVVYDGISGLIGAEIVVGIAGGMIRFPMWTLVHASTTHNEMATVT 479
Query: 498 AIMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGDPEIAKKVYQSPLSAIRVYAWGTPT 557
+++ WTQ L +L++ +G + +Y+SPL+ ++ Y G+
Sbjct: 480 GLLMSVYQIGDAVGASIAGAIWTQRLAKELIQRLGS-SLGMAIYKSPLNYLKKYPIGSEV 538
Query: 558 RDAIVEAYRHVQRFEVLVAMILVIPLFIASLC 589
R ++E+Y +QR ++V+ + F A LC
Sbjct: 539 RVQMIESYSKIQRLLIIVS--ISFAAFNAVLC 568
>SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 612
Score = 214 bits (544), Expect = 4e-55
Identities = 151/602 (25%), Positives = 267/602 (44%), Gaps = 19/602 (3%)
Query: 2 DQSDMKVNMDRKIQSRSSSFDNNEDSFPNANKENLTFAEENHKQELLDEYGVPDKLRANR 61
D S + +++ IQ +S E S +A + + EE + V K
Sbjct: 19 DSSSEEDKLEKNIQDETSI---KEVSLQDAKQSDEKGVEEKVFNDESFSIDVAPKPEDEL 75
Query: 62 SLVIRKMEIMRKQYTSVFAICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLST 121
S +++ + F IC F + FL ++ + T YAT+++ HSLLST
Sbjct: 76 SGIVKARYLTEHSSRISFYICYF--SIFLLFFAISFQAECYYSLTAYATSAFAGHSLLST 133
Query: 122 IGVVSSIISAGALTVYARLSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYS 181
I V ++IISA ARLSDVFGR+ +L ++L ++VG I+ + + NVQ YA G+V Y+
Sbjct: 134 IAVANNIISAAIKPPLARLSDVFGRLEAFLFSLLLYLVGLILMAASTNVQTYAGGSVLYN 193
Query: 182 LGTAGIQVMMFIIMSDFSSLKWRLFFTFAPTWPNLFIPWITGSIVDRLDPVERWSWGIGM 241
G G++++M I M+D SS+ R P + WI + W WGI +
Sbjct: 194 AGYTGVELIMTIFMADTSSMANRSLVLGISYLPFVVTIWIGPRVAQEFYMHSTWRWGIAV 253
Query: 242 WAFIYPLSSVPFVAYLLLVRYKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXXXXXX 301
W + P S+PF+A +++A W+ + + T + V+LF K
Sbjct: 254 WTILIPACSIPFLAVYSYYQFRA-----WREGALKGT------LTINPVELFKKLDIIGL 302
Query: 302 XXXXXXXXCILVPLTLAGGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKM 361
+L+ ++LA + +WS+ K + I+G + AF+L+E A P PF++
Sbjct: 303 ILMTAGLALVLLSISLASYDTGKWSDAKFIVMIIIGGLCLIAFVLYEIFVASFPALPFRL 362
Query: 362 LKDRGIWSALIISMLAKTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFF 421
+++ I + +S L +Y Y + L V S A I +S C F
Sbjct: 363 MREPTIGACCAMSFLFYITFYCWDNYYYSFLQVVHYTSITAAGYISYTYSFTSCATGFFL 422
Query: 422 SYFVVRVRRLKPFIIIGCGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTV 481
+ +R K + + ++++ GL+ YR +++ G I ++ G+G +I
Sbjct: 423 GILIRLTKRYKWYFVASIPVYILGQGLMIRYRGEQYNWGYQIMPQIIVGIGGGVIANLLT 482
Query: 482 ISSQSITAHENMATITAIMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGD--PEIAKK 539
++ Q++ + EN A +TA++ W + +L + + + A
Sbjct: 483 VAVQTVVSTENFAIVTALVSTVTPIGGAVGSAISGAIWNSVMPKRLEKNLPSDLKDQAYT 542
Query: 540 VYQSPLSAIRVYAWGTPTRDAIVEAYRHVQRFEVLVAMILVIPLFIASLCLRDPELTDEV 599
+++S L+ Y GT R+AI+ +Y VQ+ VA + + +P L+
Sbjct: 543 IFES-LTVQLSYTRGTDARNAIILSYSEVQKILTSVATGFAGAMIFPVWFVANPRLSTVK 601
Query: 600 AH 601
H
Sbjct: 602 TH 603
>SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 597
Score = 169 bits (427), Expect = 2e-41
Identities = 140/601 (23%), Positives = 266/601 (43%), Gaps = 29/601 (4%)
Query: 20 SFDNNEDSFPNANKENLTFAEENHKQELLDEYGVPDKLRANRSLVIRKMEIMRKQYTSVF 79
S ++ + SF N ENL ++EL + + D+ + K E + ++
Sbjct: 7 SMEHRKKSF--RNNENLEQQFHPLREELDNAGPINDRTSELSLEGVSKAEAIASTWSKRS 64
Query: 80 AICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIISAGALTVYAR 139
I +L +L + L Q + YAT+++ +HS L+TI +V +I+ A +
Sbjct: 65 IIVAYL-GLYLLSFASSLEQQTTYSLQRYATSNFSAHSNLATINLVGNILLAVVRAPMVK 123
Query: 140 LSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQVMMFIIMSDFS 199
+DVFGR A+ V+G + + + N+Q + + Y G G+ ++ +I++D S
Sbjct: 124 AADVFGRSESLSLALGMTVLGYLSLAFSRNIQMFTVAYILYICGQTGLGLLSQLIIADTS 183
Query: 200 SLKWRLFFTFAPTWPNLFIPWITGSIVDRLDPVERWSW--GIGMWAFIYPLSSVPFVAYL 257
SL R + P P L WI + P + + W G G+WAFI P S+P +A L
Sbjct: 184 SLLNRGILSAIPELPYLATVWIGPVLAQAFHPEKNYGWRLGYGIWAFILPTVSLPLLASL 243
Query: 258 LLVRYKASKTEEWKMLSSEKTYYETHGIIQ-------TLVQLFW-KXXXXXXXXXXXXXX 309
L + KA + Y E H +I L LFW +
Sbjct: 244 FLNQRKA---------KAAGLYREHHNLINHSTPEKLRLFYLFWQELDGLGIVLFVSGFT 294
Query: 310 CILVPLTLAGGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKMLKDRGIWS 369
+L+P + + V S S L L L+ ++ KYAR P+ K LKDR I
Sbjct: 295 LLLLPFSHSSQVVSPDSTILTLFTITLSIALLVTLCFYDVKYARYPVFALKSLKDRTILG 354
Query: 370 ALIISMLAKTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYFVVRVR 429
+ ++ YY+ + +L + L V+ S M+++ +NV+ + + + R
Sbjct: 355 SCVLIFTYFMSYYIFSNFLTSFLQVSYGLSIDMSSLTLNVFVFSMTTTAILSGFLMKRFG 414
Query: 430 RLKPFIIIGCGIWMVS-MGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVISSQSIT 488
R K ++I ++++ +G++ + + H ++ ++L G+G ++T + I+ QS++
Sbjct: 415 RFKMLLMISVPMYVLGILGIILFGINDNHYTRPLVLVLILAGMGGGLLTLSAQIAVQSVS 474
Query: 489 AHENMATITAIMLXXXXXXXXXXXXXXXXXWTQTLYAKLVETIGD----PEIAKKVYQSP 544
+H + + L W++ L ++L+ + D PEI + +++
Sbjct: 475 SHAKLGMNLTLYLTFSSVGGAFGSAIAGGVWSKRLSSRLLHDLKDHLPVPEI-ESIFRDL 533
Query: 545 LSAIRVYAWGTPTRDAIVEAYRHVQRFEVLVAMILVIPLFIASLCLRDPELTDEVAHTDI 604
+A+ Y GT R+ I AY ++ ++++ + +F + +RD L+ E T +
Sbjct: 534 RTALS-YPQGTQIRNIINVAYTATEKDLFHISLVASLFMFAGLVIIRDVPLSTENHDTAV 592
Query: 605 K 605
+
Sbjct: 593 E 593
>SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 630
Score = 166 bits (419), Expect = 1e-40
Identities = 126/499 (25%), Positives = 223/499 (44%), Gaps = 14/499 (2%)
Query: 97 LNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIISAGALTVYARLSDVFGRIRLYLSAMLF 156
+ S +Y YAT S+ S++ST+ + ++IIS+ + + SD+ R Y +LF
Sbjct: 100 IQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPILGKFSDITSRPMTYTLVLLF 159
Query: 157 FVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQVMMFIIMSDFSSLKWRLFFTFAPTWPNL 216
+V+G I+ + ++ + Y G+VF S+G++G+ + +++ D +SLKWR F T + P +
Sbjct: 160 YVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGDLTSLKWRGFMTALLSTPYI 219
Query: 217 FIPWITGSIVDRLDPVERWSWGIGMWAFIYPLSSVPFVAYLLLVRYKASKTEEWKMLSSE 276
W TG IV + W WG GM+A I P P V L+ + +A+K E K + +
Sbjct: 220 ATVWFTGFIVQGIID-SNWRWGYGMFAIIMPAVMTPAVIILMYLERQANKDENIKKIINY 278
Query: 277 KTYYETHGIIQTLVQLFWKXXXXXXXXXXXXX----XCILVPLTLAGGVSSQWSNGKILG 332
+T E + Q+ Q WK +L+P +L + W N ++
Sbjct: 279 QT-EEKNKNKQSKWQKLWKAVLEVDLFGLILLGVGWSILLLPFSLTSYAKNGWKNPSMIA 337
Query: 333 PFILGFCLVPAFILWETKYARLPIAPFKMLKDRGIWSALIISMLAKTVYYLAAGYLLTIL 392
++G ++ A+ +E A P P +++ +R +A+II YL + Y T
Sbjct: 338 MMVVGGVILIAYSGYEMFIAPYPSCPRRVM-NRTFITAVIIDFFYYLAGYLQSMYFTTYT 396
Query: 393 MVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYFVVRVRRLKPFIIIGCGIWMVSMGLLYYY 452
+ + S N ++ C F F R K IIG I +V G+L
Sbjct: 397 WILYDWSYRDWTYFNNTMTIALCVFGVFAGAMHRVFHRYKYLQIIGLVIKIVGYGILIRP 456
Query: 453 RSGEHSKGGIIGAMVLWGLGSTMITRTTVISSQSITAHENMATITAIMLXXXXXXXXXXX 512
K + +++L G+G + + +S Q+ H+++A ++++
Sbjct: 457 NFAATGKVDLAWSLILIGMGGSFSVVGSQVSCQASVPHQDLAIASSLLPLYTNIGGAIGA 516
Query: 513 XXXXXXWT----QTLYAKLVETIGDPEIAKKVYQSPLSAIRVYAWGTPTRDAIVEAYRHV 568
++ + L L +I D ++ + S S IR Y GT RD ++AY
Sbjct: 517 AIASPIFSNKVPKYLREYLPSSINDTQVYN--FYSDSSLIREYPVGTEIRDGAIKAYSRS 574
Query: 569 QRFEVLVAMIL-VIPLFIA 586
F ++ A+ L IPL A
Sbjct: 575 MFFLLVPAVSLSFIPLAAA 593
>YPR198w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 543
Score = 65.9 bits (159), Expect = 2e-10
Identities = 93/441 (21%), Positives = 178/441 (40%), Gaps = 45/441 (10%)
Query: 71 MRKQYTSVFAICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIIS 130
M+ + + L T FLA + + T Y T + H + +V+
Sbjct: 1 MKSTLSLTLCVISLLLTLFLAALDIVIV------VTLYDTIGIKFHDFGNIGWLVTGYAL 54
Query: 131 AGA--LTVYARLSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQ 188
+ A + ++ RL+++ G + +++ F +G++I + +N++ +G V G +GI+
Sbjct: 55 SNAVFMLLWGRLAEILGTKECLMISVIVFEIGSLISALSNSMATLISGRVVAGFGGSGIE 114
Query: 189 VMMFIIMSDFSSLKWRLFFTFAPTWPNLFI----PWITGSIVDRLDPVERWSWGIGMWAF 244
+ F++ + R A + P+I G+ + L SW W F
Sbjct: 115 SLAFVVGTSIVRENHRGIMITALAISYVIAEGVGPFIGGAFNEHL------SW---RWCF 165
Query: 245 IYPLSSVPFVAYLLLVRYKASKTEEWKM-LSSEKTYYETHGIIQTLVQLFWKXXXXXXXX 303
L F A+++L S KM L S+ + + L FWK
Sbjct: 166 YINLPIGAF-AFIILAFCNTSGEPHQKMWLPSKIKKIMNYDYGELLKASFWKNTFEVLVF 224
Query: 304 XXXXXXCIL--VPLTLA------GGVSSQWSNGKILGPFILGFCLVPAFILWETKYARL- 354
IL TL GG + W++G I+ F +G L+ F ++ + L
Sbjct: 225 KLDMVGIILSSAGFTLLMLGLSFGGNNFPWNSGIIICFFTVGPILLLLFCAYDFHFLSLS 284
Query: 355 ----------PIAPFKMLKDRGIWSALIISMLAKTVYYLAAGYLLTILMVAVNQSRGMAA 404
P+ + + + GI+++ I L+ Y L + YL+ + + + +A+
Sbjct: 285 GLHYDNKRIKPLLTWNIASNCGIFTSSITGFLSCFAYELQSAYLVQLYQLVFKKKPTLAS 344
Query: 405 VIMNVWSVVGCGFSPFFSYFVVRVRRLKPFIIIGCGIWMVSMGLLYYYRSGEHSKGGIIG 464
+ + S+ + +Y + +KP I+ G +V G L+ +GE S+ IG
Sbjct: 345 IHLWELSIPAMIATMAIAYLNSKYGIIKPAIVFGVLCGIVGSG-LFTLINGELSQS--IG 401
Query: 465 AMVLWGLGSTMITRTTVISSQ 485
+L G+ I + T++SSQ
Sbjct: 402 YSILPGIAFGSIFQATLLSSQ 422
>SPBC16A3.17c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 599
Score = 60.8 bits (146), Expect = 6e-09
Identities = 104/488 (21%), Positives = 183/488 (37%), Gaps = 54/488 (11%)
Query: 36 LTFAEENHKQELLDEYGVPDKLRANRSLVIRKMEIMRKQYTSV----------------F 79
LT N ++E+ + VPD+ + N V ++ KQ ++
Sbjct: 38 LTAYPSNEEKEVKETDIVPDENKVNELDVHKQSTEFSKQESASNDDDTNIQLIPENNMKI 97
Query: 80 AICVFLFTAFLAGVGTDLNSQLRNNYTTYATNSYRSHSLLSTIGVVSSIISAGALTVYAR 139
+ + T FLA + N+ + T A + + S S IG + S L
Sbjct: 98 VVPALILTLFLAALD---NTIVTTALPTIAED-FNDTSSSSWIGSAYVLASNAVLPAVGV 153
Query: 140 LSDVFGRIRLYLSAMLFFVVGTIIQSQANNVQKYAAGTVFYSLGTAGIQVMMFIIMSDFS 199
++ GR + + FF++G+ + + N+ LG GI ++ II+SD +
Sbjct: 154 FCNILGRKIVLYICIFFFMLGSALCGASQNMIWLIVCRAIQGLGGGGIISLVNIIISDIT 213
Query: 200 SLKWRLFFT--FAPTWPNLFI--PWITGSIVDRLDPVERWSWGIGMWAFIYPLSSVPFVA 255
L+ R ++ A W + P I G+I +R +W W F L S
Sbjct: 214 PLRTRPMYSGILATAWGAALVAGPIIGGAI------CQRTTW---RWIFFINLPSGGIAT 264
Query: 256 YLLLVRYKASKTEEWKMLSSEKTYYETHGIIQTLVQLFWKXXXXXXXXXXXXXXCILVPL 315
L++V E +S K + +T I + + IL+ +
Sbjct: 265 ALIVVFLHLLPCER----TSFKKFLKTFDFIGLVCVI-------------TGIVLILLGI 307
Query: 316 TLAGGVSSQWSNGKILGPFILGFCLVPAFILWETKYARLPIAPFKMLKDRGIWSALIISM 375
+L G S +W IL I+G CL +++T R + P K+R + L S
Sbjct: 308 SL-GASSGKWRRANILCYLIIGGCLFVFAFIYDTFTKRNAVLPPPFFKNRSSAALLACSS 366
Query: 376 LAKTVYYLAAGYLLTILMVAVNQSRGMAAVIMNVWSVVGCGFSPFFSYFVVRVRRLKPFI 435
Y L A Y+ + M+ V + V C F + ++ R P I
Sbjct: 367 FFYLNYMLFAYYVPQYFQRIRGDNPIMSGVHTIPCAAVLCFFCTTVGMVLRKLGRYLPLI 426
Query: 436 IIGCGIWMVSMGLLYYYRSGEHSKGGIIGAMVLWGLGSTMITRTTVISSQSI--TAHENM 493
+G + MG + + S ++G ++ GS + +I+ Q+ A +M
Sbjct: 427 YVGYISCVAGMGAMICV-NATTSMSKVMGLTTIFMFGSGFLFLPPLIAMQATFPPAMTSM 485
Query: 494 ATITAIML 501
AT T + +
Sbjct: 486 ATATLMFI 493
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.138 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,028,551
Number of Sequences: 60738
Number of extensions: 1323080
Number of successful extensions: 4349
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 4315
Number of HSP's gapped (non-prelim): 11
length of query: 639
length of database: 30,389,216
effective HSP length: 113
effective length of query: 526
effective length of database: 23,525,822
effective search space: 12374582372
effective search space used: 12374582372
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)