ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3799 check: MH O KOG0942 Posttranslational modification, protein turnover, chaperones E3 ubiquitin protein ligase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3799 1318958 1316241 -906
(906 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL141w [O] KOG0942 E3 ubiquitin protein ligase 454 e-127
7291760 [O] KOG0942 E3 ubiquitin protein ligase 280 7e-75
At3g17205 [O] KOG0942 E3 ubiquitin protein ligase 273 9e-73
Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase 260 6e-69
At3g53090 [O] KOG4427 E3 ubiquitin protein ligase 258 2e-68
SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase 248 3e-65
Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase 224 4e-58
CE19147 [O] KOG4427 E3 ubiquitin protein ligase 218 3e-56
7295004 [O] KOG4427 E3 ubiquitin protein ligase 211 3e-54
CE15744 [O] KOG0942 E3 ubiquitin protein ligase 210 7e-54
SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative up... 202 2e-51
YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 189 2e-47
At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 185 2e-46
At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 184 4e-46
7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 175 3e-43
CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 168 3e-41
SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 160 6e-39
YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 159 2e-38
Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase 159 2e-38
Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase 159 2e-38
Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase 159 2e-38
Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 157 7e-38
Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 156 1e-37
Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 156 2e-37
ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 155 3e-37
SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 154 6e-37
Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 154 6e-37
Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 154 6e-37
7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 152 3e-36
7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 152 3e-36
Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 150 9e-36
Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 149 2e-35
HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 147 7e-35
Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 147 7e-35
SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 145 2e-34
HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 145 3e-34
Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 145 3e-34
ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase 145 3e-34
Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 142 3e-33
7294742 [O] KOG0941 E3 ubiquitin protein ligase 140 7e-33
Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 139 2e-32
Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 138 4e-32
CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 137 7e-32
CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 137 1e-31
SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase 125 4e-28
7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstre... 125 4e-28
Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upst... 122 3e-27
7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 120 1e-26
Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase 120 1e-26
CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 117 1e-25
YJR036c [O] KOG0941 E3 ubiquitin protein ligase 116 1e-25
Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase 116 1e-25
Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase 116 1e-25
7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 115 3e-25
Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase 108 3e-23
SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase 105 3e-22
At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4 104 5e-22
CE29116 [O] KOG0941 E3 ubiquitin protein ligase 104 7e-22
Hs4758520 [S] KOG1426 FOG: RCC1 domain 102 3e-21
Hs4557026 [S] KOG1426 FOG: RCC1 domain 101 6e-21
7292061 [O] KOG0941 E3 ubiquitin protein ligase 99 2e-20
At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase 96 3e-19
Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperp... 95 4e-19
Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase 93 2e-18
CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplas... 89 4e-17
YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase 89 4e-17
CE17508 [R] KOG4276 Predicted hormone receptor interactor 84 1e-15
7297647 [R] KOG4276 Predicted hormone receptor interactor 81 8e-15
At4g38600 [O] KOG0170 E3 ubiquitin protein ligase 73 2e-12
Hs15300020 [R] KOG4276 Predicted hormone receptor interactor 73 2e-12
Hs13375805 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative ups... 67 9e-11
>YGL141w [O] KOG0942 E3 ubiquitin protein ligase
Length = 910
Score = 454 bits (1168), Expect = e-127
Identities = 314/947 (33%), Positives = 487/947 (51%), Gaps = 78/947 (8%)
Query: 1 MMNFNGQVTRRNVNMGSRAPRKTRDTILKNXXXXXXXXXXXXXXINAVLTIQRYMRKRIS 60
M+NF GQ RRNVN+G+R R ++ +L+ +A TIQ+ +R+ S
Sbjct: 1 MLNFTGQTRRRNVNLGNRT-RNSKKDLLEKAKRERERRAQDKLKEDASKTIQKSIRRHFS 59
Query: 61 NNLIFHRLVKQSLTDKTAASILKVFSKRLYAYLEPNEFVYLINRTVADSSALFLFSNMLG 120
N RL K + T ++ + +L Y+ + L+ + + L + N LG
Sbjct: 60 NV----RLFKNTFTSSQLVHMIPAYGGKLIYYISQYDLQQLLKLS---HNFLSSYPNSLG 112
Query: 121 D---VSERKTSEELDTILMRSVKSLDTPAASETHIHNKLKFVLNCPYLITDEQLSALTQP 177
+ +S K ++ D ++ ++ L+ + + L L C + S L+
Sbjct: 113 NRQLLSLLKLYQD-DALVAETLSDLNMDCPTVDEFLDSLSVYL-C-------RASFLSYS 163
Query: 178 SCNSSGEYENYWNDLY-------FISSLHTMKKENYLL-FISALFSSELKPQLQCALDRN 229
S + + W ++ F S+ + +K + L F L L PQL ++ N
Sbjct: 164 SASKLADVIEAWEVMHSSASISIFSISIGSYEKRPFALQFYCILAERNLLPQL---INTN 220
Query: 230 KDDMANYVVNFLAAFKGIKEATLSVHTSWFVIICSKLNEPLSIDVRLIDDN--------- 280
N + KG ++ ++ N ++ V D++
Sbjct: 221 PILWDNMAKTYSHCSKGGQKNIAK-------LLIPNFNNHIAPSVLRSDNDYVLKFYEKA 273
Query: 281 -LQESLLNCFDWLKEESSSYWKGIHFFLSQLPSMQ-RNSILMSILTNTHIRNDLLELLCD 338
+ E + +++ +E + K + +++ P+ +NS+L+++L+N D + L
Sbjct: 274 FIDEVIATTANYVSDED--HVKNLMCYIASSPNQSCKNSVLITLLSN----KDFVRRLSW 327
Query: 339 DSVAANLNA--------FSVCSQMLNFYIPLSPDDQL--FKTIITRDRLQALSINIAKLL 388
+ NA FSV +Q+++ ++ +S D +L + ++I + L+ + +
Sbjct: 328 EFFHTKFNASKTEAHPLFSVLAQLIDMHLLISTDRELLDYNSVIPIEELKKFTSTLKDFT 387
Query: 389 ISSILGSDTFIPSQELDTFIELMWNLIYLDSRVQFLK-KGTSTFWDLVPEEMHNLNIKKE 447
+ L + L+ + DSR+ FL + T+W+ ++ NL +E
Sbjct: 388 FRQYWELPKSERNPMLKEAVPLLSKVYERDSRLHFLSTENNPTYWENSEKQFLNLRFYEE 447
Query: 448 ILEFEQYYRAYLVRFEEMDLNEDEMFDKKKFIDQNIKGQYLDDLXXXXXXXXXXXXXLEL 507
+ E+E YR +L + D+ ++ DK++ +K L+ + LE+
Sbjct: 448 LQEYEDLYREHLEEESDEDMEKEIDLDKER---PPLKSLLLNKMKKRLKSSLRFRK-LEI 503
Query: 508 LFKFPFMIKFFERVDYFNDLIEADKIRIY--SRNSFFGVFP-----GENRLRSTIRREHA 560
L + PF I F ERVD F I DK R+ ++ +F G + + I R++
Sbjct: 504 LLELPFFIPFEERVDLFYMFIALDKKRLSLDDDHNLINMFTPWASTGMRKQSAIISRDNV 563
Query: 561 LEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFD 620
LEDA+NA+ ++GE FK L + F+NEFG EAGIDGGGITKEFL T+ EGF + +LF
Sbjct: 564 LEDAFNAFNSIGERFKASLDVTFINEFGEEAGIDGGGITKEFLTTVSDEGFKDPKHELFR 623
Query: 621 TTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVP 680
T +LYPS LKYI F+GK++GKCLYE++L+DV ADFFLKK+LN N
Sbjct: 624 TNDRYELYPSVVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSNGFLSS 683
Query: 681 FNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG-KRIPLIKDGLSTKVTQKN 739
F+DL S D Y NL+KLL M+ +E+ +DL FE+ + + K + LI +G T VT+ N
Sbjct: 684 FSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPESSAKVVDLIPNGSKTYVTKDN 743
Query: 740 VFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLED 799
V Y+T+++ YKLN + + S F GLS +I HW+ MF S EL+ LISG + DL+D
Sbjct: 744 VLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLISGERDNIDLDD 803
Query: 800 LKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIR 859
LK NT YGG+ E TI FW+VL+ F EE+ FLKFV SVP APL+GF +L+P FGIR
Sbjct: 804 LKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGIR 863
Query: 860 NAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
NAG E RLPTASTC+NLLKLPDY+N LREKLL AINS +RF+LS
Sbjct: 864 NAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARFDLS 910
>7291760 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1122
Score = 280 bits (716), Expect = 7e-75
Identities = 177/411 (43%), Positives = 247/411 (60%), Gaps = 18/411 (4%)
Query: 505 LELLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDA 564
+ +L + PF++ F +RV L+ A K+R+ F P + T+RR H EDA
Sbjct: 721 ITILREIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGPS---VLITVRRSHLYEDA 777
Query: 565 YNAYGAVGEM-FKEKLGIQFVNEFG-PEAGIDGGGITKEFLQTLVQEGFI-NQPFKLFDT 621
Y+ E + K IQFV+ G EAGIDGGG+ +EFL L++ F N+ F F
Sbjct: 778 YDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGF--FMV 835
Query: 622 TSFNKLYPSKNVSP---QNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMN 678
T+ NKLYP+ NV+ K+ F+G+ILGK +YEN+LV++ LA+FFL K+ ++++
Sbjct: 836 TTDNKLYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKYSDVD 895
Query: 679 VPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKR--IPLIKDGLSTKVT 736
+ + L SLDPE YRNL+ L + S +++ ++L F V + G+ + L G S VT
Sbjct: 896 I--HQLASLDPELYRNLLYLKDYS-GDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVT 952
Query: 737 QKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFD 796
N EY+ I+ YKLN+Q+ + F GLS ++P WL MF++ EL+ LISG+E D
Sbjct: 953 NSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPID 1012
Query: 797 LEDLKKNTSYGG-FSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPL 855
LEDLKK+ YGG FS +I FW+VL F +RR+ LKFV S PL GF L+P
Sbjct: 1013 LEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPP 1072
Query: 856 FGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
F I+N GD +RLPTASTC NLLKLP ++ +REKLL AI S + FELS
Sbjct: 1073 FFIQNTGD-MERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFELS 1122
>At3g17205 [O] KOG0942 E3 ubiquitin protein ligase
Length = 873
Score = 273 bits (698), Expect = 9e-73
Identities = 162/413 (39%), Positives = 242/413 (58%), Gaps = 26/413 (6%)
Query: 507 LLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYN 566
+L + PF+I F RV F + + S+ F NR R IRR+H LEDAYN
Sbjct: 474 ILMQAPFLIPFTSRVKIFTTQLATARQSHGSQGIF-----ARNRFR--IRRDHILEDAYN 526
Query: 567 AYGAVGEM-FKEKLGIQFVNEFG-PEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSF 624
A+ E + + + FVNE G EAGIDGGGI K+F++ + + F Q + LF T+
Sbjct: 527 QMSALSEDDLRSSIRVTFVNELGVEEAGIDGGGIFKDFMEKITRAAFDVQ-YGLFKETAD 585
Query: 625 NKLYPSKN---VSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPF 681
+ LYP+ + Q+L++ F+G +L K ++E ILVD+ A FFL K+ N +N
Sbjct: 586 HMLYPNPGSGMIHEQHLQFFHFLGSLLAKAMFEGILVDIPFATFFLSKLKQKYNYLN--- 642
Query: 682 NDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRIP--LIKDGLSTKVTQKN 739
DL SLDPE YR+L+ L+ + +++ ++LYF + + G+R L+ G +VT +N
Sbjct: 643 -DLPSLDPELYRHLI-FLKRYKGDISDLELYFVILNNEYGERTEEELLPGGQDMRVTNEN 700
Query: 740 VFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLED 799
V +I +S+++LN Q+ +S F+ G +IP W+ MF +EL+ LISGS D++D
Sbjct: 701 VITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIPKEWIDMFNEHELQVLISGSVDSLDIDD 760
Query: 800 LKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGI 858
L+ NT+Y GG+ I FW+V+ SF+ E ++KFLKFV PL GF L P F I
Sbjct: 761 LRNNTNYAGGYHAGHYVIDMFWEVMKSFSTENQKKFLKFVTGCSRGPLLGFKYLEPAFCI 820
Query: 859 RNA-----GDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
+ A + DRLPT++TC+NLLKLP YQ+ L KL+ AI++++ F+LS
Sbjct: 821 QRAAGSASNESVDRLPTSATCMNLLKLPPYQSKELLETKLMYAISAEAGFDLS 873
>Hs7661856 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1083
Score = 260 bits (665), Expect = 6e-69
Identities = 167/412 (40%), Positives = 234/412 (56%), Gaps = 21/412 (5%)
Query: 505 LELLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDA 564
L +L + PF++ F ERV F LI ADK + F + + TIRR + EDA
Sbjct: 683 LAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFL------DGINVTIRRNYIYEDA 736
Query: 565 YNAYGAVGEM-FKEKLGIQFVNEFG-PEAGIDGGGITKEFLQTLVQEGFI-NQPFKLFDT 621
Y+ E K+++ + +N G EAGIDGGGI +EFL L++ GF NQ F F T
Sbjct: 737 YDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGF--FKT 794
Query: 622 TSFNKLYPSKN----VSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNM 677
T+ LYP+ V ++ F+ ++LGK LYEN+LV++ A FFL K+L ++
Sbjct: 795 TNEGLLYPNPAAQMLVGDSFARHYYFLARMLGKALYENMLVELPFAGFFLSKLLGTSADV 854
Query: 678 NVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKR--IPLIKDGLSTKV 735
++ + L SLDPE Y+NL+ L+ E+++ + L F V + G+ + L G V
Sbjct: 855 DI--HHLASLDPEVYKNLL-FLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPV 911
Query: 736 TQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDF 795
T N YI ++ Y+LN Q+ F GL+ ++ WLRMF E++ LISG++
Sbjct: 912 TSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPI 971
Query: 796 DLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNP 854
LEDLK T+Y GG+S I+ FW+V+ FT EE+RK LKFV S PL GF L P
Sbjct: 972 SLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYP 1031
Query: 855 LFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
F I N G + +RLPTASTC+NLLKLP++ + LR KLL AI + FELS
Sbjct: 1032 AFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS 1083
>At3g53090 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1142
Score = 258 bits (660), Expect = 2e-68
Identities = 160/414 (38%), Positives = 229/414 (54%), Gaps = 27/414 (6%)
Query: 512 PFMIKFFERVDYFNDLIEADKIRIYSRNSFFGV-FPGENRLRSTIRREHALEDAYNAYGA 570
P + F ERV F + I DK SR V PG + +RR H +ED + +
Sbjct: 737 PHVFPFEERVHVFREFISKDKA---SRKMAGEVDAPGARSIEIVVRRGHVVEDGFQQLNS 793
Query: 571 VGEMFKEKLGIQFVNEFG-PEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLY- 628
+G K + + FVNE G PEAG+D GG++KEFL + + F + T + ++L
Sbjct: 794 IGSRLKSSIHVSFVNESGLPEAGLDYGGLSKEFLTDITKAAFATEYGLFSQTPTSDRLLV 853
Query: 629 --PSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYS 686
PS ++ I F+G+I+GK LYE IL+D + F++K+L + ++ +L
Sbjct: 854 PSPSARHLENGIQMIEFLGRIVGKALYEGILLDYSFSHVFIQKLLGRYSFID----ELSG 909
Query: 687 LDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKR--IPLIKDGLSTKVTQKNVFEYI 744
LDPE YRNLM ++ + +L + L F V + GK I L G T VT +N +YI
Sbjct: 910 LDPELYRNLM-YVKHYDGDLKELCLDFTVTEEFCGKMSIIELKPGGKDTSVTNENKMQYI 968
Query: 745 TRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNT 804
++ YKLN Q+ ++ F GL+ +I WL++F ++E L+SG D D++DL++NT
Sbjct: 969 HAMADYKLNRQIVPFSNAFYRGLTDLISPAWLKLFNAHEFNQLLSGGNHDIDVDDLRRNT 1028
Query: 805 SY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRN--- 860
Y GG+S+SS TI+ FW+V+ F P ER LKFV S APL GF L P F I
Sbjct: 1029 KYTGGYSDSSRTIKIFWEVMKGFEPSERCLLLKFVTSCSRAPLLGFKYLQPTFIIHKVSC 1088
Query: 861 --------AGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
G + +RLP+ASTC N LKLP Y+ T+REKLL AI S++ FELS
Sbjct: 1089 DTSLWAAIGGQDVERLPSASTCYNTLKLPTYKRASTMREKLLYAITSNAGFELS 1142
>SPAC167.07c [O] KOG0942 E3 ubiquitin protein ligase
Length = 1029
Score = 248 bits (633), Expect = 3e-65
Identities = 166/478 (34%), Positives = 245/478 (50%), Gaps = 26/478 (5%)
Query: 437 EEMHNLNIKKEILEFEQYYRAYLVRFEEMDLNEDEMFDKKKFIDQNIKGQYLDDLXXXXX 496
++++ +N +K+ L + + + E + N + + + I Y D
Sbjct: 570 QQLYRINSRKQFLPEDFFLMSEYFNLNEFEANALQESELASHAEAEINITYKFD------ 623
Query: 497 XXXXXXXXLELLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIR 556
L +L F + F R+ L+ DK N + P + + IR
Sbjct: 624 NFSESRPRLNILNNCSFFLPFHFRIHLLQQLLLLDK----QANGY--AQPFGHLKHAVIR 677
Query: 557 REHALEDAYNAYGAVGEMFKEKLGIQFVNEFGP-EAGIDGGGITKEFLQTLVQEGF-INQ 614
R +D ++A+ G++ K + I FV+E G E GIDGGG+TKEFL ++ + F IN
Sbjct: 678 RNRIFDDGFDAFYNFGKLLKGPIRITFVDEHGVVEEGIDGGGLTKEFLTSICKTVFDIN- 736
Query: 615 PFKLFDTTSFNKLYPSKNVSPQN---LKYISFMGKILGKCLYENILVDVELADFFLKKIL 671
+ LF T + LYP+ + Q+ L+ F+G ++GKC+YE I +D A FF+ K L
Sbjct: 737 -YGLFSETKAHLLYPNTHAYAQDVERLRCYEFLGMLIGKCIYEGIQIDAAFASFFVAKWL 795
Query: 672 NVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKR--IPLIKD 729
+ F+DL SLDP Y L+ L + M L F V G R I LI +
Sbjct: 796 GHPSY----FDDLTSLDPNLYEGLVFLKNYDGDVENDMALNFTVVHEEFGVRNVIDLIPN 851
Query: 730 GLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLIS 789
G + VT +N +YI +S+Y LN +L F G + +I HWL MF E++ L+
Sbjct: 852 GSNISVTNENRLQYIHLVSNYYLNARLSRQCRAFTNGFTQIIDPHWLAMFHESEIQILVG 911
Query: 790 GSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKG 848
G D++DL+++T Y GG+ +S TI FW+VL F E++R F+KFV SV P+ G
Sbjct: 912 GDPVPIDIDDLRRHTVYAGGYEPNSPTIVLFWEVLREFEEEDKRSFVKFVTSVARPPILG 971
Query: 849 FHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
F +L P F IR G++ RLPTASTC+NLLKLP Y TLR+KLLTA+ S F S
Sbjct: 972 FKALMPSFCIRVNGEDETRLPTASTCVNLLKLPMYSTKQTLRDKLLTAVRSGVGFGFS 1029
>Hs22061896 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1068
Score = 224 bits (572), Expect = 4e-58
Identities = 176/517 (34%), Positives = 260/517 (50%), Gaps = 66/517 (12%)
Query: 432 WDLVPEEMHNLNIKKEILEFEQYYRAYLVRFEEMDLN-----EDEMFDKKKFIDQNIKGQ 486
WD + E N K E LE Q +L+ E D ED +K + ++ Q
Sbjct: 576 WDGIVE-----NAKGETLELFQSVHGWLMVLYERDCRRRFTPEDHWL--RKDLKPSVLFQ 628
Query: 487 YLDDLXXXXXXXXXXXXXLELLFKF-PFMIKFFERVDYFNDLI--EADKIRIYSRNSFFG 543
LD +L+ ++ P +I RV F ++ E +K+ + +S
Sbjct: 629 ELD----------RDRKRAQLILQYIPHVIPHKNRVLLFRTMVTKEKEKLGLVETSS--- 675
Query: 544 VFPGENRLRSTIRREHALEDAYNAYGAVGE-MFKEKLGIQFVNEFG-PEAGIDGGGITKE 601
+ TIRR LED Y + + K + ++FVN+ G EAGID G+ KE
Sbjct: 676 --ASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKE 733
Query: 602 FLQTLVQEGFINQPFKLFDTTSFN-KLYPSKN--VSPQNLKYISFMGKILGKCLYENILV 658
FL+ +++ F + LF TTS + +LYPS + L+ F+GK+LGK +YE I+V
Sbjct: 734 FLEEIIKRVF-DPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVV 792
Query: 659 DVELADFFLKKILNVENNMNVP-FNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPD 717
DV A FFL ++L +++ ++L SLD E+Y+NL + + + ++ + L +
Sbjct: 793 DVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSI-KRYDGDITDLGLTLSYDE 851
Query: 718 APNGKRI--PLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHW 775
G+ + LI G + VT +N YI ++H++++ Q+ T+ I+G +I W
Sbjct: 852 DVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEW 911
Query: 776 LRMFTSYELKTLISGSEKDFDLEDLKKNT-SYGGFSESSVTIQHFWQVLSS-FTPEERRK 833
+RMF++ EL+ LISG + DLEDLKK+T YGGF S I W +L+S FTP+ER
Sbjct: 912 IRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAM 971
Query: 834 FLKFVFSVPTAPLKGFHSLNPLFGIR--NAGDETD----------------------RLP 869
FLKFV S PL GF L P F IR D+ D RLP
Sbjct: 972 FLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLP 1031
Query: 870 TASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
T+STC NLLKLP+Y LREKL AI+ ++ FELS
Sbjct: 1032 TSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS 1068
>CE19147 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1066
Score = 218 bits (556), Expect = 3e-56
Identities = 150/432 (34%), Positives = 225/432 (51%), Gaps = 41/432 (9%)
Query: 507 LLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYN 566
++ K ++ +R+ F ++ DK R+ + + + + T++R +ED +N
Sbjct: 644 MMRKMAHLVPIKDRMLLFRRQVQDDKNRVAT-----SLNDPQMQTWITVQRNRIIEDGFN 698
Query: 567 AYGAVG-EMFKEKLGIQFVNEFG-PEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSF 624
+ K + ++FVNE G EAGID G+ KEFL+ +++ F Q LF TTS
Sbjct: 699 HLSKLTIPALKSTIRVKFVNEQGLDEAGIDQDGVFKEFLELTLKKVFDPQ-LNLFSTTST 757
Query: 625 NKLYPSKNVS--PQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFN 682
LYPS S +L +F+G++LGK +YE I+VDV+LA L +L ++ F+
Sbjct: 758 GVLYPSPTSSLHDDHLALFTFVGRMLGKAVYEGIVVDVQLAPVLLAAVLG--SHRLCAFD 815
Query: 683 DLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGK--RIPLIKDGLSTKVTQKNV 740
+L LDPE YR+L ++ E E+A + L F V + GK + L+ G + VT +N
Sbjct: 816 ELSQLDPELYRSLT-FVKRYEGEMADLSLTFSVDEDFMGKISTVDLVPSGRTISVTNENK 874
Query: 741 FEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDL 800
+Y+ R++H+++ + F+TG+ ++ WL +F +L+ LISG D DL DL
Sbjct: 875 IDYVHRMAHHRVFRRTQEQCKAFVTGMQSILQPTWLSLFAPNDLQCLISGVNSDIDLADL 934
Query: 801 KKNTSY-GGFSESSVTIQHFWQVL-SSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGI 858
K+N Y GGF + I+ W +L + FT EER+ FLKFV S P+ GF L P F I
Sbjct: 935 KRNVQYFGGFHGNHRLIKWLWDILENKFTSEERKLFLKFVTSCSRPPVLGFSYLEPPFSI 994
Query: 859 R------------------------NAGDETDRLPTASTCINLLKLPDYQNYHTLREKLL 894
R G RLPTASTC NLLKLP+Y L EKL
Sbjct: 995 RCVEVSDDQDQGDTLGSVVRGFLALRKGTAATRLPTASTCFNLLKLPNYNKKSLLLEKLR 1054
Query: 895 TAINSDSRFELS 906
AI++ + FELS
Sbjct: 1055 YAIHAGTGFELS 1066
>7295004 [O] KOG4427 E3 ubiquitin protein ligase
Length = 1078
Score = 211 bits (538), Expect = 3e-54
Identities = 150/433 (34%), Positives = 222/433 (50%), Gaps = 38/433 (8%)
Query: 507 LLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYN 566
LL K P +I +RV F ++ +K + S I R+ +ED Y
Sbjct: 651 LLAKMPHIIPHEDRVKLFRKFVQNEKAVMGLTES---ACASPRSALIVIHRDRIVEDGYR 707
Query: 567 AYGAVG-EMFKEKLGIQFVNEFG-PEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSF 624
A + K + ++F+N+ G EAGID G+ KEFL+ +++ F + LF TTS
Sbjct: 708 QLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVF-DPSLNLFKTTSD 766
Query: 625 NKLYPS--KNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILN-VENNMNVPF 681
+LYPS V +L+ F+G++LGK +YE I+VDV A FFL ++L + +
Sbjct: 767 QRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCM 826
Query: 682 NDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRIPLI--KDGLSTKVTQKN 739
++L SLD E YR+L ++ + +++ ++L F V GK + L G + V N
Sbjct: 827 DELPSLDNELYRSLT-FIKHYKQDVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHN 885
Query: 740 VFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLED 799
YI ++ + +N Q+ T F G ++ WL +F+ EL+ LISG DL+D
Sbjct: 886 KLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKD 945
Query: 800 LKKNTSY-GGFSESSVTIQHFWQVLSS-FTPEERRKFLKFVFSVPTAPLKGFHSLNPLFG 857
L+K+T Y GGF ++ + W +L+ FT EER+ FLKFV S PL GF L P F
Sbjct: 946 LQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFS 1005
Query: 858 IR------------------------NAGDETDRLPTASTCINLLKLPDYQNYHTLREKL 893
IR D +RLPT+STC NLLKLP+YQ TLR+KL
Sbjct: 1006 IRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKL 1065
Query: 894 LTAINSDSRFELS 906
A++S++ FELS
Sbjct: 1066 RYAVSSNTGFELS 1078
>CE15744 [O] KOG0942 E3 ubiquitin protein ligase
Length = 1001
Score = 210 bits (535), Expect = 7e-54
Identities = 132/409 (32%), Positives = 215/409 (52%), Gaps = 19/409 (4%)
Query: 512 PFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYNAY--- 568
PF++ F +RV F L+ DK + Y+ S FG+ G N T+RR+ DA+ +
Sbjct: 598 PFIVPFMDRVKLFTRLLNQDKEKHYT--STFGM--GFNGPSVTVRRDQVYMDAFETFAPK 653
Query: 569 --GAVGEMFKEKLGIQFVNEFGP-EAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN 625
G K + ++ VN G E+GIDGGGI +EFL L++ F N F T
Sbjct: 654 MQGDKVNDLKSMVRVKMVNWAGMNESGIDGGGIFREFLSELLKTAF-NVERGFFTFTESK 712
Query: 626 KLYPSKN----VSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPF 681
LYP+ + L + F+G+++GK +YE L +V A+FF+ +I + N +V
Sbjct: 713 LLYPNPTAPFLLGVDCLAHFQFIGRMIGKLIYERQLQEVRFAEFFIAQIFETDKNKDVDL 772
Query: 682 NDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG--KRIPLIKDGLSTKVTQKN 739
+ S DP +++L L +M+ EL + L F V + G + + L +G +VT +N
Sbjct: 773 QHMKSFDPIIFKHLKALQKMNNRELDELQLDFSVVTSDMGLVRNVNLKPNGSKFRVTVEN 832
Query: 740 VFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLED 799
V EY+ +Y L ++ ++ G+S +I W+RMF +EL+ +I+G E+ F ++
Sbjct: 833 VHEYVRLYVNYHLKQRIASMVDAVRKGISEIISIEWMRMFAPHELQIMIAGYEEVFTAKE 892
Query: 800 LKK--NTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFG 857
L+K + ++ + FW V+ + ++++ LKFV AP+ GF S+ P G
Sbjct: 893 LRKFCELRFAAGTQDINYEEMFWDVIDKLSNDDKKALLKFVTGCSRAPVDGFKSIQPRMG 952
Query: 858 IRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFELS 906
+ D LPT++TC+N+L++P Y N L EKL AINS + FEL+
Sbjct: 953 VLVIPSSDDELPTSATCMNMLRIPKYSNRTKLEEKLRYAINSGAGFELA 1001
>SPAC19D5.04 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3227
Score = 202 bits (514), Expect = 2e-51
Identities = 135/407 (33%), Positives = 208/407 (50%), Gaps = 34/407 (8%)
Query: 507 LLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYN 566
LL K P +++F + +YFN + + + +P L T+RR+H D+Y
Sbjct: 2837 LLVKNPKVLEFENKRNYFNRQLHEEAAKEQ--------YPP---LNITVRRDHVFLDSYR 2885
Query: 567 A--YGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLF----- 619
A + E+ KL I F +E G+D GG+T+E+LQ L ++ F N + LF
Sbjct: 2886 ALHFKDADEVKFSKLNIHFRDE----EGVDAGGVTREWLQVLARQMF-NPDYALFLPVTG 2940
Query: 620 DTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNV 679
D T+F+ S +V+P +L + F G+I+GK LY+ L+D + K +L+ +V
Sbjct: 2941 DATTFHPNRDS-SVNPDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYKHMLH----RSV 2995
Query: 680 PFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRIPLIKDGLSTKVTQKN 739
D+ SLDP+YY++L+ +L ++ + E + LI +G + VT+ N
Sbjct: 2996 SVKDIESLDPDYYKSLVWMLNNDITDIITEEFAVEKDVFGEKTVVDLIPNGRNIPVTELN 3055
Query: 740 VFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLED 799
Y+ R+ YKL + + G S +IP+H +++F EL+ LISG + D++D
Sbjct: 3056 KQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHLIQIFNEQELELLISGLP-EIDIDD 3114
Query: 800 LKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPL---- 855
K NT Y G++ SS +Q FW+ + SF EER K L+F PL GF L +
Sbjct: 3115 WKNNTEYHGYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQ 3174
Query: 856 -FGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDS 901
F I + +RLP + TC N L LP+Y Y LR LLTAIN S
Sbjct: 3175 RFNIHKSYGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGS 3221
>YDR457w [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3268
Score = 189 bits (479), Expect = 2e-47
Identities = 128/404 (31%), Positives = 200/404 (48%), Gaps = 36/404 (8%)
Query: 507 LLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYN 566
LL K P ++ F + +FN +++D +L T+RRE D+Y
Sbjct: 2880 LLVKNPKVLDFDNKRYFFNAKLKSDNQE-------------RPKLPITVRREQVFLDSYR 2926
Query: 567 A--YGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLF----- 619
A + E+ KL I F E +G+D GG+T+E+ Q L ++ F N + LF
Sbjct: 2927 ALFFKTNDEIKNSKLEITFKGE----SGVDAGGVTREWYQVLSRQMF-NPDYALFLPVPS 2981
Query: 620 DTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNV 679
D T+F+ S ++P++L + F+G I+GK + + +D + K IL V
Sbjct: 2982 DKTTFHPNRTS-GINPEHLSFFKFIGMIIGKAIRDQCFLDCHFSREVYKNILG----RPV 3036
Query: 680 PFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRIPLIKDGLSTKVTQKN 739
D+ SLDP+YY++L+ +LE ++ E D K I LI+ G VT+ N
Sbjct: 3037 SLKDMESLDPDYYKSLVWILENDITDIIEETFSVETDDYGEHKVINLIEGGKDIIVTEAN 3096
Query: 740 VFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLED 799
+Y+ ++ YKL + F+ G +I + +F EL+ LISG D D++D
Sbjct: 3097 KQDYVKKVVEYKLQTSVKEQMDNFLVGFYALISKDLITIFDEQELELLISGL-PDIDVDD 3155
Query: 800 LKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPL---- 855
K NT+Y ++ + + +FW+ + SF EER K L+FV PL GF L+ +
Sbjct: 3156 WKNNTTYVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVC 3215
Query: 856 -FGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
F I ++RLP++ TC N L LP Y++Y TLR LL AIN
Sbjct: 3216 KFSIHRDFGSSERLPSSHTCFNQLNLPPYESYETLRGSLLLAIN 3259
>At1g55860 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3891
Score = 185 bits (470), Expect = 2e-46
Identities = 132/416 (31%), Positives = 211/416 (49%), Gaps = 43/416 (10%)
Query: 505 LELLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDA 564
L ++ K P +I F + YF I + S LR ++RR + LED+
Sbjct: 3494 LSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHIS-----------GPLRISVRRAYVLEDS 3542
Query: 565 YNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTS 623
YN K +L +QF E GID GG+T+E+ Q L + F ++ LF T
Sbjct: 3543 YNQLRMRSPQDLKGRLNVQFQGE----EGIDAGGLTREWYQLLSRVIF-DKGALLFTTVG 3597
Query: 624 FNKLY---PSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVP 680
+ + P+ ++L Y F+G+++ K L++ L+DV F K IL V+ V
Sbjct: 3598 NDATFQPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVK----VT 3653
Query: 681 FNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRI----------PLIKDG 730
++D+ ++DP+YY+NL LLE +++ +DL F + DA K I L G
Sbjct: 3654 YHDIEAVDPDYYKNLKWLLENDVSDI--LDLTFSM-DADEEKHILYEKTEVTDYELKPGG 3710
Query: 731 LSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISG 790
+ +VT++ EY+ ++ + L + + F+ G + +IP + +F EL+ LISG
Sbjct: 3711 RNIRVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNELIPRELVSIFNDKELELLISG 3770
Query: 791 SEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFH 850
+ D +DLK NT Y ++ S I FW+V+ +F+ E+ +FL+FV PL+GF
Sbjct: 3771 LP-EIDFDDLKANTEYTSYTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFK 3829
Query: 851 SLNPLFG-----IRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDS 901
+L + G I A +RLP+A TC N L LP+YQ+ L+E+LL AI+ S
Sbjct: 3830 ALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEAS 3885
>At1g70320 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 3658
Score = 184 bits (468), Expect = 4e-46
Identities = 130/411 (31%), Positives = 211/411 (50%), Gaps = 43/411 (10%)
Query: 507 LLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYN 566
++ K P +I F + YF I + S LR ++RR + LED+YN
Sbjct: 3263 MMLKAPRLIDFDNKKAYFRSRIRHQHDQHIS-----------GPLRISVRRAYVLEDSYN 3311
Query: 567 AYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN 625
K +L +QF E GID GG+T+E+ Q L + F ++ LF T +
Sbjct: 3312 QLRMRSPQDLKGRLNVQFQGE----EGIDAGGLTREWYQLLSRVIF-DKGALLFTTVGND 3366
Query: 626 KLY---PSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFN 682
+ P+ ++L Y F+G+++ K L++ L+DV F K IL V+ V ++
Sbjct: 3367 ATFQPNPNSVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVK----VTYH 3422
Query: 683 DLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRI----------PLIKDGLS 732
D+ ++DP+YY+NL LLE +++ +DL F + DA K I L G +
Sbjct: 3423 DIEAVDPDYYKNLKWLLENDVSDI--LDLTFSM-DADEEKHILYEKTEVTDYELKPGGRN 3479
Query: 733 TKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSE 792
+VT++ EY+ ++ + L + + F+ GL+ +IP + +F EL+ LISG
Sbjct: 3480 IRVTEETKHEYVDLVADHILTSAIRPQINAFLEGLNELIPRELVSIFNDKELELLISGLP 3539
Query: 793 KDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSL 852
+ D +DLK NT Y ++ S I+ FW+V+ +F+ E+ +FL+FV PL+GF +L
Sbjct: 3540 -EIDFDDLKANTEYTSYTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKAL 3598
Query: 853 NPLFG-----IRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
+ G I A +RLP+A TC N L LP+YQ+ ++E+LL AI+
Sbjct: 3599 QGISGPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIH 3649
>7293111 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 5002
Score = 175 bits (443), Expect = 3e-43
Identities = 121/359 (33%), Positives = 184/359 (50%), Gaps = 21/359 (5%)
Query: 554 TIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFIN 613
++RR ED++ +G E+ +F F E G D GG+ +E+ + +E F N
Sbjct: 4648 SVRRVTVFEDSFRVLYRLGP---EEWKNRFYIVFEDEEGQDAGGLLREWYVIISREIF-N 4703
Query: 614 QPFKLFDTTSFNK----LYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKK 669
+ LF + ++ + PS + +P +L Y F+G+++ K +++N L++ F K
Sbjct: 4704 PMYALFCVSPGDRVTYMINPSSHANPNHLSYFKFVGRVIAKAVHDNKLLECYFTRSFYKH 4763
Query: 670 ILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYF--EVPDAPNGKRIPLI 727
IL + V D+ S D E+Y+ L L++ + L Y +L F EV + + L
Sbjct: 4764 ILGKQ----VKHTDMESQDYEFYKGLDYLMKNDISTLGY-ELTFSTEVQEFGVTQIRDLK 4818
Query: 728 KDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTL 787
+G T VT++N FEY+ + K++ + F+ G +IP H + +F EL+ L
Sbjct: 4819 PNGRDTAVTEENKFEYVQLVCQLKMSGSIRQQLDAFLEGFYDIIPKHLISIFNEQELELL 4878
Query: 788 ISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLK 847
ISG D D+EDLK NT Y ++ S IQ FW+ L SF +R KFL+FV PL+
Sbjct: 4879 ISGLP-DIDIEDLKANTEYHKYTSKSAQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQ 4937
Query: 848 GFHSLNPL-----FGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDS 901
GF SL + F I TDRLP A TC N L LP Y++Y LR LL AI+ S
Sbjct: 4938 GFGSLEGMNGIQKFQIHRDDRSTDRLPCAHTCFNQLDLPMYKSYDKLRSCLLKAIHECS 4996
>CE25443 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 875
Score = 168 bits (426), Expect = 3e-41
Identities = 125/399 (31%), Positives = 192/399 (47%), Gaps = 32/399 (8%)
Query: 518 FERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRST-----IRREHALEDAYNAYGAVG 572
F + F L++ D R Y R + P R R + R D++
Sbjct: 480 FAILTQFPKLLDFDVKRKYFRKELTKLEPSMPRYRRNDVSVQVSRNRVFSDSFR------ 533
Query: 573 EMFK---EKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLYP 629
E+F+ + +F F E G D GG+ +E+ + +E F N + LF T + +
Sbjct: 534 ELFRLRPSEWKNRFYIIFQGEEGQDAGGLLREWFSVITREIF-NPNYALFITAPGDMVTY 592
Query: 630 SKN----VSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLY 685
N ++P++L Y F+G+++ K ++E+ +D F K ILN+ V + DL
Sbjct: 593 MINKASYINPEHLDYFKFVGRLIAKSVFEHKYLDCYFTRAFYKHILNLP----VRYQDLE 648
Query: 686 SLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRI--PLIKDGLSTKVTQKNVFEY 743
S DP ++++L LL+ ++LA +DL F G R L +G +V N EY
Sbjct: 649 SEDPAFFKSLDFLLQNPIDDLA-LDLTFSTEVEEFGVRSVRDLKPNGRKIEVNDANKDEY 707
Query: 744 ITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKN 803
+ + K+ + F+TG +IP + MF EL+ LISG D++D+ N
Sbjct: 708 VKLVCQMKMTGSIRKQLDAFLTGFYEIIPKDLISMFNEQELELLISGLPT-VDIDDMAAN 766
Query: 804 TSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGD 863
T Y GF ++S IQ FW+ L SF E++ KFL+FV PL+GF SL + G++
Sbjct: 767 TDYKGFQKTSTHIQWFWRALRSFEKEDKAKFLQFVTGTSKVPLQGFASLEGMNGVQKFSI 826
Query: 864 ET-----DRLPTASTCINLLKLPDYQNYHTLREKLLTAI 897
DRLP A TC N L LP Y++Y LR+ LL AI
Sbjct: 827 HMDSRGGDRLPAAHTCFNQLDLPQYESYEKLRQSLLLAI 865
>SPAC11G7.02 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 767
Score = 160 bits (406), Expect = 6e-39
Identities = 111/370 (30%), Positives = 190/370 (51%), Gaps = 27/370 (7%)
Query: 546 PGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQT 605
PG+ ++ +RR H ED+Y + L + + +F E G+D GG+++E+
Sbjct: 410 PGQCHIK--VRRNHIFEDSY---AEIMRQSATDLKKRLMIKFDGEDGLDYGGLSREYFFL 464
Query: 606 LVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVE 661
L E F N + LF+ +S + ++ P ++P++L Y F+G+++G ++ VD
Sbjct: 465 LSHEMF-NPFYCLFEYSSVDNYTLQINPHSGINPEHLNYFKFIGRVIGLAIFHRRFVDAF 523
Query: 662 LADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELA-YMDLYFEVPDAPN 720
F K IL + V D+ S+D EYYR+L+ +L+ N++ +DL F V D
Sbjct: 524 FVVSFYKMILQKK----VTLQDMESMDAEYYRSLVWILD---NDITGVLDLTFSVEDNCF 576
Query: 721 GK--RIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRM 778
G+ I L +G + +VT++N EY+ ++ +++ ++ + F G S +IP + +
Sbjct: 577 GEVVTIDLKPNGRNIEVTEENKREYVDLVTVWRIQKRIEEQFNAFHEGFSELIPQELINV 636
Query: 779 FTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFV 838
F EL+ LI G + D+ED KK+T Y +SE+ I+ FW+++ ++ E++ + L+F
Sbjct: 637 FDERELELLIGGIS-EIDMEDWKKHTDYRSYSENDQIIKWFWELMDEWSNEKKSRLLQFT 695
Query: 839 FSVPTAPLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKL 893
P+ GF L F I AG E ++LP A TC N L LP Y + L KL
Sbjct: 696 TGTSRIPVNGFKDLQGSDGPRKFTIEKAG-EPNKLPKAHTCFNRLDLPPYTSKKDLDHKL 754
Query: 894 LTAINSDSRF 903
A+ F
Sbjct: 755 SIAVEETIGF 764
>YER125w [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 809
Score = 159 bits (402), Expect = 2e-38
Identities = 107/371 (28%), Positives = 189/371 (50%), Gaps = 25/371 (6%)
Query: 544 VFPGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFL 603
+ PG+ ++ +RR++ EDAY + E L + + +F E G+D GG+++EF
Sbjct: 450 ILPGQCHIK--VRRKNIFEDAYQE---IMRQTPEDLKKRLMIKFDGEEGLDYGGVSREFF 504
Query: 604 QTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVD 659
L E F N + LF+ ++++ ++ P+ ++P++L Y F+G+++G ++ +D
Sbjct: 505 FLLSHEMF-NPFYCLFEYSAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLD 563
Query: 660 VELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAP 719
FF+ + + V D+ +D E Y +L +LE S + + +DL F D
Sbjct: 564 A----FFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDGV--LDLTFSADDER 617
Query: 720 NGK--RIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLR 777
G+ + L DG + +VT N EY+ + +++ ++ F+ G + +IP +
Sbjct: 618 FGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVT 677
Query: 778 MFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKF 837
+F EL+ LI G + D+ED KK+T Y G+ ES IQ FW+ +S + E+R + L+F
Sbjct: 678 VFDERELELLIGGIA-EIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQF 736
Query: 838 VFSVPTAPLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREK 892
P+ GF L F I AG E +LP + TC N + LP Y +Y ++++K
Sbjct: 737 TTGTSRIPVNGFKDLQGSDGPRRFTIEKAG-EVQQLPKSHTCFNRVDLPQYVDYDSMKQK 795
Query: 893 LLTAINSDSRF 903
L A+ F
Sbjct: 796 LTLAVEETIGF 806
>Hs19718766 [O] KOG0941 E3 ubiquitin protein ligase
Length = 875
Score = 159 bits (402), Expect = 2e-38
Identities = 115/378 (30%), Positives = 185/378 (48%), Gaps = 19/378 (5%)
Query: 531 DKIRIYSRNSF---FGVFPGENR---LRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFV 584
++IR+YS + + G+ LR +RR+H ++DA + L Q
Sbjct: 497 NRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLY 556
Query: 585 NEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLYPSKNVSPQNLKYISFM 644
EF E G+D GG++KEF Q +V+E F N +F KL+ S + + +
Sbjct: 557 VEFEGEQGVDEGGVSKEFFQLVVEEIF-NPDIGMFTYDESTKLFWFNPSSFETEGQFTLI 615
Query: 645 GKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSEN 704
G +LG +Y N ++DV +K++ + F DL P Y++L LLE N
Sbjct: 616 GIVLGLAIYNNCILDVHFPMVVYRKLMGKKGT----FRDLGDSHPVLYQSLKDLLEYEGN 671
Query: 705 ELAYMDLYFEVPDAP---NGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTS 761
M + F++ N L ++G +T +N E++ S Y LN +
Sbjct: 672 VEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFK 731
Query: 762 RFITGLSYMIPAHWLR-MFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHF 819
F G + L+ +F E++ LI GS ++ D + L++ T Y GG++ SV I+ F
Sbjct: 732 AFRRGFHMVTNESPLKYLFRPEEIELLICGS-RNLDFQALEETTEYDGGYTRDSVLIREF 790
Query: 820 WQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLK 879
W+++ SFT E++R FL+F AP+ G L + I G +T+RLPT+ TC N+L
Sbjct: 791 WEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMI--IAKNGPDTERLPTSHTCFNVLL 848
Query: 880 LPDYQNYHTLREKLLTAI 897
LP+Y + L+E+LL AI
Sbjct: 849 LPEYSSKEKLKERLLKAI 866
>Hs19718764 [O] KOG0941 E3 ubiquitin protein ligase
Length = 872
Score = 159 bits (402), Expect = 2e-38
Identities = 115/378 (30%), Positives = 185/378 (48%), Gaps = 19/378 (5%)
Query: 531 DKIRIYSRNSF---FGVFPGENR---LRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFV 584
++IR+YS + + G+ LR +RR+H ++DA + L Q
Sbjct: 494 NRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLY 553
Query: 585 NEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLYPSKNVSPQNLKYISFM 644
EF E G+D GG++KEF Q +V+E F N +F KL+ S + + +
Sbjct: 554 VEFEGEQGVDEGGVSKEFFQLVVEEIF-NPDIGMFTYDESTKLFWFNPSSFETEGQFTLI 612
Query: 645 GKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSEN 704
G +LG +Y N ++DV +K++ + F DL P Y++L LLE N
Sbjct: 613 GIVLGLAIYNNCILDVHFPMVVYRKLMGKKGT----FRDLGDSHPVLYQSLKDLLEYEGN 668
Query: 705 ELAYMDLYFEVPDAP---NGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTS 761
M + F++ N L ++G +T +N E++ S Y LN +
Sbjct: 669 VEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFK 728
Query: 762 RFITGLSYMIPAHWLR-MFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHF 819
F G + L+ +F E++ LI GS ++ D + L++ T Y GG++ SV I+ F
Sbjct: 729 AFRRGFHMVTNESPLKYLFRPEEIELLICGS-RNLDFQALEETTEYDGGYTRDSVLIREF 787
Query: 820 WQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLK 879
W+++ SFT E++R FL+F AP+ G L + I G +T+RLPT+ TC N+L
Sbjct: 788 WEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMI--IAKNGPDTERLPTSHTCFNVLL 845
Query: 880 LPDYQNYHTLREKLLTAI 897
LP+Y + L+E+LL AI
Sbjct: 846 LPEYSSKEKLKERLLKAI 863
>Hs19718762 [O] KOG0941 E3 ubiquitin protein ligase
Length = 852
Score = 159 bits (402), Expect = 2e-38
Identities = 115/378 (30%), Positives = 185/378 (48%), Gaps = 19/378 (5%)
Query: 531 DKIRIYSRNSF---FGVFPGENR---LRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFV 584
++IR+YS + + G+ LR +RR+H ++DA + L Q
Sbjct: 474 NRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLY 533
Query: 585 NEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLYPSKNVSPQNLKYISFM 644
EF E G+D GG++KEF Q +V+E F N +F KL+ S + + +
Sbjct: 534 VEFEGEQGVDEGGVSKEFFQLVVEEIF-NPDIGMFTYDESTKLFWFNPSSFETEGQFTLI 592
Query: 645 GKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSEN 704
G +LG +Y N ++DV +K++ + F DL P Y++L LLE N
Sbjct: 593 GIVLGLAIYNNCILDVHFPMVVYRKLMGKKGT----FRDLGDSHPVLYQSLKDLLEYEGN 648
Query: 705 ELAYMDLYFEVPDAP---NGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTS 761
M + F++ N L ++G +T +N E++ S Y LN +
Sbjct: 649 VEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFK 708
Query: 762 RFITGLSYMIPAHWLR-MFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHF 819
F G + L+ +F E++ LI GS ++ D + L++ T Y GG++ SV I+ F
Sbjct: 709 AFRRGFHMVTNESPLKYLFRPEEIELLICGS-RNLDFQALEETTEYDGGYTRDSVLIREF 767
Query: 820 WQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLK 879
W+++ SFT E++R FL+F AP+ G L + I G +T+RLPT+ TC N+L
Sbjct: 768 WEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMI--IAKNGPDTERLPTSHTCFNVLL 825
Query: 880 LPDYQNYHTLREKLLTAI 897
LP+Y + L+E+LL AI
Sbjct: 826 LPEYSSKEKLKERLLKAI 843
>Hs13929476 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 308
Score = 157 bits (397), Expect = 7e-38
Identities = 103/307 (33%), Positives = 159/307 (51%), Gaps = 17/307 (5%)
Query: 606 LVQEGFINQPFKLFDTTSFNK----LYPSKNVSPQNLKYISFMGKILGKCLYENILVDVE 661
++ N + LF T+ ++ + PS + +P +L Y F+G+I+ K +Y+N L++
Sbjct: 2 IISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECY 61
Query: 662 LADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYF--EVPDAP 719
F K IL +V + D+ S D +Y+ L+ LLE + L Y DL F EV +
Sbjct: 62 FTRSFYKHILG----KSVRYTDMESEDYHFYQGLVYLLENDVSTLGY-DLTFSTEVQEFG 116
Query: 720 NGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMF 779
+ L +G + VT++N EY+ + ++ + + F+ G +IP + +F
Sbjct: 117 VCEVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIF 176
Query: 780 TSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVF 839
T EL+ LISG D++DLK NT Y + +S+ IQ FW+ L SF +R KFL+FV
Sbjct: 177 TEQELELLISGLPT-IDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVT 235
Query: 840 SVPTAPLKGFHSLNPL-----FGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLL 894
PL+GF +L + F I TDRLP+A TC N L LP Y+++ LR LL
Sbjct: 236 GTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLL 295
Query: 895 TAINSDS 901
AI S
Sbjct: 296 LAIQECS 302
>Hs14759464 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 562
Score = 156 bits (395), Expect = 1e-37
Identities = 111/340 (32%), Positives = 173/340 (50%), Gaps = 29/340 (8%)
Query: 576 KEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLF----DTTSFNKLYPSK 631
K+ + ++F E G G G+ +E+ L E +N + LF D T+F P+
Sbjct: 232 KQGIAVRFHGEEGM-----GQGVVREWFDILSNE-IVNPDYALFTQSADGTTFQ---PNS 282
Query: 632 N--VSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDP 689
N V+P +L Y F G+ILG L LV++ F K IL + N + D+ S+DP
Sbjct: 283 NSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVN----YQDVASIDP 338
Query: 690 EYYRNLMKLLEMSENELAYMDLYFEVPDAPNG--KRIPLIKDGLSTKVTQKNVFEYITRI 747
EY +NL +L+ ++L ++L F V G + +PL G S VTQ N EY+ +
Sbjct: 339 EYAKNLQWILDNDISDLG-LELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLV 397
Query: 748 SHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY- 806
+ ++ + + F+ G IP +++F YEL+ L+SG + D+ D KNT Y
Sbjct: 398 TELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMP-EIDVSDWIKNTEYT 456
Query: 807 GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRN-----A 861
G+ IQ FW+V+ T EER L+FV P GF ++ G++N
Sbjct: 457 SGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAV 516
Query: 862 GDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDS 901
+ LPT+STCIN+LKLP+Y + L+++LL A++ S
Sbjct: 517 PYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGS 556
>Hs22062809 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1606
Score = 156 bits (394), Expect = 2e-37
Identities = 118/390 (30%), Positives = 194/390 (49%), Gaps = 25/390 (6%)
Query: 529 EADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYNAYGAVG--EMFKEKLGIQFVNE 586
EA Y + G G +++ IRR+H LE +N A E+ + KL + FV E
Sbjct: 1228 EAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGE 1287
Query: 587 FGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYIS 642
G+D G ++EF L QE F N + LF+ ++ + ++ P +L++
Sbjct: 1288 ----EGLDYSGPSREFFFLLSQELF-NPYYGLFEYSANDTYTVQISPMSAFVENHLEWFR 1342
Query: 643 FMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMS 702
F G+ILG L L+D F K +L + +++ DL LD E++++L + + +
Sbjct: 1343 FSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLS----DLEYLDEEFHQSLQWMKDNN 1398
Query: 703 ENELAYMDLYFEVPDAPNGK--RIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVT 760
++ +DL F V + G+ L G +T+VT+KN EYI R+ +++ + T
Sbjct: 1399 ITDI--LDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQT 1456
Query: 761 SRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHF 819
+ G ++ + + +F + EL+ +I+G+ + DL D + NT Y GG+ + + I+ F
Sbjct: 1457 EALVRGFYEVVDSRLVSVFDARELELVIAGTA-EIDLNDWRNNTEYRGGYHDGHLVIRWF 1515
Query: 820 WQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDET----DRLPTASTCI 875
W + F E+R + L+FV + P +GF +L G+R E LP A TC
Sbjct: 1516 WAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCF 1575
Query: 876 NLLKLPDYQNYHTLREKLLTAINSDSRFEL 905
N L LP Y +Y L EKLLTA+ S F L
Sbjct: 1576 NRLDLPPYPSYSMLYEKLLTAVEETSTFGL 1605
>ECU10g1380 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream regulatory
element binding protein
Length = 2410
Score = 155 bits (391), Expect = 3e-37
Identities = 101/321 (31%), Positives = 165/321 (50%), Gaps = 15/321 (4%)
Query: 590 EAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNK--LYPSKN--VSPQNLKYISFMG 645
E G+D GG+T+E+L L ++ ++ F LF+ + +K + P KN V+P++L Y F+G
Sbjct: 2090 EEGLDYGGLTREWLVLLAKD-LLDPNFALFEFATEDKTTVVPCKNSYVNPEHLSYFKFVG 2148
Query: 646 KILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENE 705
+I+ K + + +++ L+ F + IL ++ DL S DPE++++L+ + + ++
Sbjct: 2149 RIIAKAIMDGNFINLHLSKFIYQYILGKSCDLQ----DLESADPEFHKSLVWIRDNPVDK 2204
Query: 706 LAYMDLYFEVPDAPNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFIT 765
+ F+ + + L++ G V N EY+ + Y+L + S +
Sbjct: 2205 SLGITFSFDDVSFGVHRTVELVEGGAHVFVDDSNKAEYVKLATQYRLFNGIELQLSALKS 2264
Query: 766 GLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSS 825
GL ++ + L MF EL+ LI G D D++D K NT Y G++E+S T+ FW+ + S
Sbjct: 2265 GLFEILGSKALEMFDESELELLICGIP-DIDVDDWKNNTLYYGYAENSKTVIWFWRAVKS 2323
Query: 826 FTPEERRKFLKFVFSVPTAPLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKL 880
R K L+FV T P +GF L F I D D LPTA TC N L L
Sbjct: 2324 LDSVSRAKLLQFVTGTSTLPFEGFSHLQGNNEVQKFSIHKVSDRIDSLPTAHTCFNQLVL 2383
Query: 881 PDYQNYHTLREKLLTAINSDS 901
P+Y +Y L + L AIN S
Sbjct: 2384 PEYSSYENLLKYLTLAINECS 2404
>SPBC16E9.11c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 786
Score = 154 bits (389), Expect = 6e-37
Identities = 105/373 (28%), Positives = 190/373 (50%), Gaps = 25/373 (6%)
Query: 543 GVFPGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEF 602
G+ P + +RR+H ED+Y + L + + F E G+D GG+++EF
Sbjct: 424 GMRPLPGQCNVKVRRDHIFEDSY---AEIMRYSAHDLKKRLMIRFDGEDGLDYGGLSREF 480
Query: 603 LQTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILV 658
L + F + + LF+ ++ + ++ P +++P++L Y F+G+++G ++ +
Sbjct: 481 FFLLSHKMF-DPIYCLFEYSAVDNYTLQINPHSSINPEHLNYFRFIGRVIGLAIFHRRFL 539
Query: 659 DVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELA-YMDLYFEVPD 717
D KK+L + V D+ S+D E+YR+L +LE N++ +DL F V +
Sbjct: 540 DAFFVVSLYKKLLRKK----VSLADMESIDAEFYRSLKWVLE---NDITGILDLTFSVEE 592
Query: 718 APNG--KRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHW 775
G + + LI +G + +VT++N +Y+ ++ ++++ ++ + F +G ++
Sbjct: 593 DHFGEVRTVELITNGENIEVTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVELVSPDL 652
Query: 776 LRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFL 835
+ +F EL+ LI G D D+ED K +T Y + + I+ FW++++ + E+R K L
Sbjct: 653 VNVFDERELELLIGGIS-DVDVEDWKSHTEYRTYIATDPVIKWFWEIIAGWKNEDRSKLL 711
Query: 836 KFVFSVPTAPLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLR 890
+F P+ GF L F I AG D+LP A TC N L LPDY + TL
Sbjct: 712 QFATGTSRIPVNGFRDLQGSDGPRKFTIEKAG-TPDQLPVAHTCFNRLDLPDYPSKDTLH 770
Query: 891 EKLLTAINSDSRF 903
EKL A+ + F
Sbjct: 771 EKLSLAVENTVGF 783
>Hs5902156 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 154 bits (389), Expect = 6e-37
Identities = 105/325 (32%), Positives = 166/325 (50%), Gaps = 19/325 (5%)
Query: 590 EAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMG 645
E G+D GGI +E+ L E +N + LF+ N ++ P+ +++P +L Y F+G
Sbjct: 551 EEGLDYGGIAREWFFLLSHE-VLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIG 609
Query: 646 KILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENE 705
+ + LY +D F K++LN + DL S+DPE+Y +++ + E + E
Sbjct: 610 RFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLK----DLESIDPEFYNSIVWIKENNLEE 665
Query: 706 LAYMDLYFEVPDAPNGKRIP--LIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRF 763
++LYF GK L + G S +VT++N EYI ++ ++ + T F
Sbjct: 666 CG-LELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAF 724
Query: 764 ITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVL 823
+ G + + P WLR F EL+ ++ G + + D+ D +K+T Y ++++S IQ FWQV+
Sbjct: 725 LDGFNEVAPLEWLRYFDEKELELMLCGMQ-EIDMSDWQKSTIYRHYTKNSKQIQWFWQVV 783
Query: 824 SSFTPEERRKFLKFVFSVPTAPLKGFHSL-----NPLFGIRNAGDETDRLPTASTCINLL 878
E+R + L+FV P+ GF L F I G ET LP + TC N L
Sbjct: 784 KEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKET-WLPRSHTCFNRL 842
Query: 879 KLPDYQNYHTLREKLLTAINSDSRF 903
LP Y++Y LREKLL AI F
Sbjct: 843 DLPPYKSYEQLREKLLYAIEETEGF 867
>Hs22067492 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 870
Score = 154 bits (389), Expect = 6e-37
Identities = 105/325 (32%), Positives = 166/325 (50%), Gaps = 19/325 (5%)
Query: 590 EAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMG 645
E G+D GGI +E+ L E +N + LF+ N ++ P+ +++P +L Y F+G
Sbjct: 551 EEGLDYGGIAREWFFLLSHE-VLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIG 609
Query: 646 KILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENE 705
+ + LY +D F K++LN + DL S+DPE+Y +++ + E + E
Sbjct: 610 RFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLK----DLESIDPEFYNSIVWIKENNLEE 665
Query: 706 LAYMDLYFEVPDAPNGKRIP--LIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRF 763
++LYF GK L + G S +VT++N EYI ++ ++ + T F
Sbjct: 666 CG-LELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAF 724
Query: 764 ITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVL 823
+ G + + P WLR F EL+ ++ G + + D+ D +K+T Y ++++S IQ FWQV+
Sbjct: 725 LDGFNEVAPLEWLRYFDEKELELMLCGMQ-EIDMSDWQKSTIYRHYTKNSKQIQWFWQVV 783
Query: 824 SSFTPEERRKFLKFVFSVPTAPLKGFHSL-----NPLFGIRNAGDETDRLPTASTCINLL 878
E+R + L+FV P+ GF L F I G ET LP + TC N L
Sbjct: 784 KEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKET-WLPRSHTCFNRL 842
Query: 879 KLPDYQNYHTLREKLLTAINSDSRF 903
LP Y++Y LREKLL AI F
Sbjct: 843 DLPPYKSYEQLREKLLYAIEETEGF 867
>7296014 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 949
Score = 152 bits (383), Expect = 3e-36
Identities = 105/366 (28%), Positives = 188/366 (50%), Gaps = 22/366 (6%)
Query: 549 NRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQ 608
+ ++ T+ R+ ED+Y+ + + +L + F E G+D GG+++E+ L
Sbjct: 592 SHIKITVTRQTLFEDSYHQ---IMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSH 648
Query: 609 EGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELAD 664
E +N + LF+ + N ++ P+ V+P +L+Y F+G+ + LY +
Sbjct: 649 E-VLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTM 707
Query: 665 FFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRI 724
F K++LN + + D+ ++DPE+Y +L+ + + + +E ++L+F V G+ I
Sbjct: 708 PFYKRMLNKK----LTIKDIETIDPEFYNSLIWVKDNNIDECG-LELWFSVDFEVLGQII 762
Query: 725 --PLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSY 782
L ++G +VT++N EYIT ++ +++ + T F+ G + ++P WL+ F
Sbjct: 763 HHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDER 822
Query: 783 ELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVP 842
EL+ ++ G + D D+ED ++NT Y ++ +S + FWQ + E+R + L+FV
Sbjct: 823 ELELILCGMQ-DVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTC 881
Query: 843 TAPLKGFHSL-----NPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAI 897
P+ GF L F I G ET LP + TC N L LP Y++Y L EKL AI
Sbjct: 882 RVPVGGFAELMGSNGPQRFCIEKVGKET-WLPRSHTCFNRLDLPPYKSYDQLVEKLTFAI 940
Query: 898 NSDSRF 903
F
Sbjct: 941 EETEGF 946
>7293969 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1082
Score = 152 bits (383), Expect = 3e-36
Identities = 109/370 (29%), Positives = 184/370 (49%), Gaps = 29/370 (7%)
Query: 549 NRLRSTIRREHALEDAYNAYGAVG--EMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTL 606
N+ IRR LED+Y +V ++ K KL + EF E G+D GG+ +E+ L
Sbjct: 723 NKFEIRIRRTSILEDSYRIISSVTKTDLLKTKLWV----EFEGETGLDYGGLAREWFYLL 778
Query: 607 VQEGFINQPFKLFDTTSFNKLYPSKN-----VSPQNLKYISFMGKILGKCLYENILVDVE 661
+E F N + LF+ ++ + N + ++L Y F+G+I G +Y L+D
Sbjct: 779 SKEMF-NPYYGLFEYSAMDNYTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDA- 836
Query: 662 LADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG 721
FF++ + + D+ S+D EYY +LM + EN+ ++L F + + G
Sbjct: 837 ---FFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWI---KENDPRILELTFCLDEDVFG 890
Query: 722 KRIP--LIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMF 779
++ L G + VT +N EYI + ++ ++ S F+ G +IP + +++F
Sbjct: 891 QKSQHELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIF 950
Query: 780 TSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFV 838
+EL+ L+ G + + D++D ++NT Y G + + + IQ FW+ + SF+ E R + L+FV
Sbjct: 951 DEHELELLMCGIQ-NIDVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFV 1009
Query: 839 FSVPTAPLKGFHSL-----NPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKL 893
P+ GF L +F I G + P A TC N L LP Y+ Y L++KL
Sbjct: 1010 TGTSRVPMNGFKELYGSNGPQMFTIEKWG-TPNNFPRAHTCFNRLDLPPYEGYLQLKDKL 1068
Query: 894 LTAINSDSRF 903
+ AI F
Sbjct: 1069 IKAIEGSQGF 1078
>Hs14730213 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1572
Score = 150 bits (379), Expect = 9e-36
Identities = 119/392 (30%), Positives = 192/392 (48%), Gaps = 29/392 (7%)
Query: 529 EADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYNAYGAVG--EMFKEKLGIQFVNE 586
EA Y + G G +L+ IRR+H LEDA+N ++ + KL + FV E
Sbjct: 1194 EAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGE 1253
Query: 587 FGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLYPSKNVSPQNL------KY 640
G+D G ++EF LV N + LF+ ++ N Y + +SP + ++
Sbjct: 1254 ----EGLDYSGPSREFF-FLVSRELFNPYYGLFEYSA-NDTY-TVQISPMSAFVDNHHEW 1306
Query: 641 ISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLE 700
F G+ILG L L+D F K +L + +++ DL LD E++++L + +
Sbjct: 1307 FRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLS----DLEYLDEEFHQSLQWMKD 1362
Query: 701 MSENELAYMDLYFEVPDAPNGK--RIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYT 758
+++ +DL F V + G+ L G + VT+KN EYI R+ +++ +
Sbjct: 1363 NDIHDI--LDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQ 1420
Query: 759 VTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQ 817
T + G ++ A + +F + EL+ +I+G+ + DL D + NT Y GG+ ++ + I+
Sbjct: 1421 QTESLVRGFYEVVDARLVSVFDARELELVIAGTA-EIDLSDWRNNTEYRGGYHDNHIVIR 1479
Query: 818 HFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDET----DRLPTAST 873
FW + F E+R + L+FV + P +GF SL G R E LP A T
Sbjct: 1480 WFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHT 1539
Query: 874 CINLLKLPDYQNYHTLREKLLTAINSDSRFEL 905
C N L LP Y ++ L EKLLTA+ S F L
Sbjct: 1540 CFNRLDLPPYPSFSMLYEKLLTAVEETSTFGL 1571
>Hs20539203 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 757
Score = 149 bits (375), Expect = 2e-35
Identities = 113/396 (28%), Positives = 190/396 (47%), Gaps = 30/396 (7%)
Query: 523 YFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQ 582
Y DL++ K+ R+ P R + RE E++Y + +M + L +
Sbjct: 374 YERDLVQKLKVL---RHELSLQQPQAGHCRIEVSREEIFEESYRQ---IMKMRPKDLKKR 427
Query: 583 FVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNL 638
+ +F E G+D GG+ +E+L L E +N + LF ++ N ++ P +++P +L
Sbjct: 428 LMVKFRGEEGLDYGGVAREWLYLLCHE-MLNPYYGLFQYSTDNIYMLQINPDSSINPDHL 486
Query: 639 KYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKL 698
Y F+G+I+G ++ ++ F K++L + +DL S+DPE +++L+ +
Sbjct: 487 SYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKP----IQLSDLESVDPELHKSLVWI 542
Query: 699 LEMSENELA-YMDLYFEVPDAPNGKRIP--LIKDGLSTKVTQKNVFEYITRISHYKLNLQ 755
LE N++ +D F V G+ + L +G + VT++N EY+ +++
Sbjct: 543 LE---NDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRG 599
Query: 756 LYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVT 815
+ G + +IP H L+ F EL+ +I G +K DL D K NT S
Sbjct: 600 IEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDK-IDLNDWKSNTRLKHCVADSNI 658
Query: 816 IQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNP--------LFGIRNAGDETDR 867
++ FWQ + +F E R + L+FV PL+GF +L LF I TD
Sbjct: 659 VRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDN 718
Query: 868 LPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRF 903
LP A TC N + +P Y++Y L EKLLTA+ F
Sbjct: 719 LPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGF 754
>HsM14010859 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 862
Score = 147 bits (371), Expect = 7e-35
Identities = 106/365 (29%), Positives = 182/365 (49%), Gaps = 24/365 (6%)
Query: 551 LRSTIRREHALEDAYNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQE 609
++ T+ R+ ED++ + + +L + F E G+D GG+ +E+ L E
Sbjct: 507 IKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGE----EGLDYGGVAREWFFLLSHE 562
Query: 610 GFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADF 665
+N + LF+ + ++ P+ ++P +LKY F+G+ + L+ +D +
Sbjct: 563 -VLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLP 621
Query: 666 FLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG--KR 723
F K+ILN V DL S+DPE+Y +L+ + E + E +++YF V G K
Sbjct: 622 FYKRILNKP----VGLKDLESIDPEFYNSLIWVKENNIEECD-LEMYFSVDKEILGEIKS 676
Query: 724 IPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYE 783
L +G + VT++N EYI ++ ++L+ + T F G + ++P +L+ F + E
Sbjct: 677 HDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKE 736
Query: 784 LKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPT 843
L+ L+ G + + DL D +++ Y ++ +S I FWQ + E+R + L+FV
Sbjct: 737 LEVLLCGMQ-EIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCR 795
Query: 844 APLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
P+ GF L F I G E + LP + TC N L LP Y++Y L+EKLL AI
Sbjct: 796 LPVGGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIE 854
Query: 899 SDSRF 903
F
Sbjct: 855 ETEGF 859
>Hs21361973 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 903
Score = 147 bits (371), Expect = 7e-35
Identities = 106/365 (29%), Positives = 182/365 (49%), Gaps = 24/365 (6%)
Query: 551 LRSTIRREHALEDAYNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQE 609
++ T+ R+ ED++ + + +L + F E G+D GG+ +E+ L E
Sbjct: 548 IKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGE----EGLDYGGVAREWFFLLSHE 603
Query: 610 GFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADF 665
+N + LF+ + ++ P+ ++P +LKY F+G+ + L+ +D +
Sbjct: 604 -VLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLP 662
Query: 666 FLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG--KR 723
F K+ILN V DL S+DPE+Y +L+ + E + E +++YF V G K
Sbjct: 663 FYKRILNKP----VGLKDLESIDPEFYNSLIWVKENNIEECD-LEMYFSVDKEILGEIKS 717
Query: 724 IPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYE 783
L +G + VT++N EYI ++ ++L+ + T F G + ++P +L+ F + E
Sbjct: 718 HDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKE 777
Query: 784 LKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPT 843
L+ L+ G + + DL D +++ Y ++ +S I FWQ + E+R + L+FV
Sbjct: 778 LEVLLCGMQ-EIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCR 836
Query: 844 APLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
P+ GF L F I G E + LP + TC N L LP Y++Y L+EKLL AI
Sbjct: 837 LPVGGFADLMGSNGPQKFCIEKVGKE-NWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIE 895
Query: 899 SDSRF 903
F
Sbjct: 896 ETEGF 900
>SPAC1805.15c [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 671
Score = 145 bits (367), Expect = 2e-34
Identities = 103/364 (28%), Positives = 177/364 (48%), Gaps = 21/364 (5%)
Query: 550 RLRSTIRREHALEDAYNAYG--AVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLV 607
+L+ + R EDAY+ +V +M K+KL I+F NE G+D GG+++EF L
Sbjct: 316 QLQLKVSRATTFEDAYDIISKLSVSDM-KKKLLIRFRNE----DGLDYGGVSREFFYIL- 369
Query: 608 QEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELA 663
N + LF+ + + ++ P +V+P Y F+G+++G +Y +DV+
Sbjct: 370 SHAIFNPGYSLFEYATDDNYGLQISPLSSVNPDFRSYFRFVGRVMGLAIYHRRYLDVQFV 429
Query: 664 DFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKR 723
F K+IL + D+ +D YY +L + +E ++ E
Sbjct: 430 LPFYKRILQKP----LCLEDVKDVDEVYYESLKWIKNNDVDESLCLNFSVEENRFGESVT 485
Query: 724 IPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYE 783
+ LI +G + V +N Y+ ++ +KL + GL+ +IP L++F E
Sbjct: 486 VDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGGLNELIPDSVLQIFNENE 545
Query: 784 LKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPT 843
L TL++G ++D D++D K+ T Y ++E+ + FW++LS ++PE++ K L+F
Sbjct: 546 LDTLLNG-KRDIDVQDWKRFTDYRSYTETDDIVIWFWELLSEWSPEKKAKLLQFATGTSR 604
Query: 844 APLKGFHSLNPLFGIRNAGDE----TDRLPTASTCINLLKLPDYQNYHTLREKLLTAINS 899
PL GF ++ G R E +LP A TC N L +P Y + L +KL AI
Sbjct: 605 LPLSGFKDMHGSDGPRKFTIEKVGHISQLPKAHTCFNRLDIPPYNSKEELEQKLTIAIQE 664
Query: 900 DSRF 903
+ F
Sbjct: 665 TAGF 668
>HsM14719404 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 854
Score = 145 bits (366), Expect = 3e-34
Identities = 112/410 (27%), Positives = 199/410 (48%), Gaps = 46/410 (11%)
Query: 512 PFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGE--NRLRSTIRREHALEDAYNAYG 569
P+ +F ++ DYF ++ P + NR + R + E++Y
Sbjct: 471 PYSREFKQKYDYFRKKLKK---------------PADIPNRFEMKLHRNNIFEESYRRIM 515
Query: 570 AVG--EMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN-- 625
+V ++ K +L I EF E G+D GG+ +E+ L +E F N + LF+ ++ +
Sbjct: 516 SVKRPDVLKARLWI----EFESEKGLDYGGVAREWFFLLSKEMF-NPYYGLFEYSATDNY 570
Query: 626 --KLYPSKNV-SPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFN 682
++ P+ + + +L Y +F+G++ G ++ L+D FF++ + + N
Sbjct: 571 TLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLD----GFFIRPFYKMMLGKQITLN 626
Query: 683 DLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGK--RIPLIKDGLSTKVTQKNV 740
D+ S+D EYY +L +LE EL DL F + + G+ ++ L +G VT +N
Sbjct: 627 DMESVDSEYYNSLKWILENDPTEL---DLMFCIDEENFGQTYQVDLKPNGSEIMVTNENK 683
Query: 741 FEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDL 800
EYI + ++ ++ + F+ G + ++P +++F EL+ L+ G D D+ D
Sbjct: 684 REYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLG-DVDVNDW 742
Query: 801 KKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLN-----P 854
++++ Y G+ + IQ FW+ + E+R + L+FV P+ GF L
Sbjct: 743 RQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQ 802
Query: 855 LFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFE 904
LF I G ++LP A TC N L LP Y+ + LREKLL A+ + FE
Sbjct: 803 LFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFE 851
>Hs21361472 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 955
Score = 145 bits (366), Expect = 3e-34
Identities = 112/410 (27%), Positives = 199/410 (48%), Gaps = 46/410 (11%)
Query: 512 PFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGE--NRLRSTIRREHALEDAYNAYG 569
P+ +F ++ DYF ++ P + NR + R + E++Y
Sbjct: 572 PYSREFKQKYDYFRKKLKK---------------PADIPNRFEMKLHRNNIFEESYRRIM 616
Query: 570 AVG--EMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN-- 625
+V ++ K +L I EF E G+D GG+ +E+ L +E F N + LF+ ++ +
Sbjct: 617 SVKRPDVLKARLWI----EFESEKGLDYGGVAREWFFLLSKEMF-NPYYGLFEYSATDNY 671
Query: 626 --KLYPSKNV-SPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFN 682
++ P+ + + +L Y +F+G++ G ++ L+D FF++ + + N
Sbjct: 672 TLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLD----GFFIRPFYKMMLGKQITLN 727
Query: 683 DLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGK--RIPLIKDGLSTKVTQKNV 740
D+ S+D EYY +L +LE EL DL F + + G+ ++ L +G VT +N
Sbjct: 728 DMESVDSEYYNSLKWILENDPTEL---DLMFCIDEENFGQTYQVDLKPNGSEIMVTNENK 784
Query: 741 FEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDL 800
EYI + ++ ++ + F+ G + ++P +++F EL+ L+ G D D+ D
Sbjct: 785 REYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLG-DVDVNDW 843
Query: 801 KKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLN-----P 854
++++ Y G+ + IQ FW+ + E+R + L+FV P+ GF L
Sbjct: 844 RQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQ 903
Query: 855 LFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFE 904
LF I G ++LP A TC N L LP Y+ + LREKLL A+ + FE
Sbjct: 904 LFTIEQWGSP-EKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFE 952
>ECU04g0490 [O] KOG0941 E3 ubiquitin protein ligase
Length = 746
Score = 145 bits (366), Expect = 3e-34
Identities = 118/407 (28%), Positives = 203/407 (48%), Gaps = 27/407 (6%)
Query: 505 LELLFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFF-GVFPG--ENRLRSTIRREHAL 561
L F P IK E + Y N+ D+++ ++SFF +F G + L T+ RE
Sbjct: 360 LNFQFILPVHIKA-ELIKYENN----DRMKTSLQDSFFKSLFEGHVDPYLFITVSRETVY 414
Query: 562 EDAYNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFD 620
D+ + + + +++L I F NE G+D GGI KE+ Q L QE I + +LF+
Sbjct: 415 RDSIEIFKKINVLDARKQLRITFRNE----EGVDSGGIRKEYFQLLSQE--IKEDERLFE 468
Query: 621 TTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVP 680
T N+++ + + +G+I+ LY N+++++ F KK+L+ ++
Sbjct: 469 HTE-NRIWIRPHEGDG--EGYEAIGRIIAIALYNNVVLNIPFPSLFFKKLLDRRPTLD-- 523
Query: 681 FNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG--KRIPLIKDGLSTKVTQK 738
DL + +L L +S +E+ +DL F V + +G + PL+K+G K+T +
Sbjct: 524 --DLREISSGIATSLRNLRRLSRDEVDSLDLRFVVEHSVDGIPRSYPLVKNGEDIKLTSE 581
Query: 739 NVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLE 798
N+ +I + + + + G +I L EL+ ++ GS FD++
Sbjct: 582 NMRLFIEKYVEFHTDALIKPQFESIKRGFYSIIDKDKLAYLDPKELEKIMMGSNT-FDIK 640
Query: 799 DLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGI 858
++ T+Y GF E S I +FW++ +F ++R+K L+F+ P+ G SL L +
Sbjct: 641 AIRSTTTYSGFREDSPIIVYFWEIFEAFNRKKRKKLLQFITGNDRIPVSGPASLK-LVIM 699
Query: 859 RNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFEL 905
RN G +TDRLP++ TC N L LP+Y + L KL TA+ + F L
Sbjct: 700 RN-GCDTDRLPSSQTCFNTLLLPEYSSKDKLEGKLETALELTAGFFL 745
>Hs13654239 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 922
Score = 142 bits (357), Expect = 3e-33
Identities = 98/328 (29%), Positives = 164/328 (49%), Gaps = 19/328 (5%)
Query: 587 FGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYIS 642
F E G+D GG+ +E+ L E +N + LF+ N ++ P+ ++P +L Y
Sbjct: 600 FRGEEGLDYGGLAREWFFLLSHE-VLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFC 658
Query: 643 FMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMS 702
F+G+ + L+ +D + F K++L+ + + DL S+D E+Y +L+ + + +
Sbjct: 659 FIGRFIAMALFHGKFIDTGFSLPFYKRMLSKK----LTIKDLESIDTEFYNSLIWIRDNN 714
Query: 703 ENELAYMDLYFEVPDAPNGKRIP--LIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVT 760
E +++YF V GK L G + VT++N EYI ++ ++ + + T
Sbjct: 715 IEECG-LEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQT 773
Query: 761 SRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFW 820
F+ G + ++P WL+ F EL+ ++ G + + DL D ++NT Y ++ +S I FW
Sbjct: 774 KAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQ-EVDLADWQRNTVYRHYTRNSKQIIWFW 832
Query: 821 QVLSSFTPEERRKFLKFVFSVPTAPLKGFHSL-----NPLFGIRNAGDETDRLPTASTCI 875
Q + E R + L+FV PL GF L F I G +T LP + TC
Sbjct: 833 QFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDT-WLPRSHTCF 891
Query: 876 NLLKLPDYQNYHTLREKLLTAINSDSRF 903
N L LP Y++Y L+EKLL AI F
Sbjct: 892 NRLDLPPYKSYEQLKEKLLFAIEETEGF 919
>7294742 [O] KOG0941 E3 ubiquitin protein ligase
Length = 973
Score = 140 bits (354), Expect = 7e-33
Identities = 107/367 (29%), Positives = 175/367 (47%), Gaps = 30/367 (8%)
Query: 551 LRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEG 610
L+ T+RR+ + DA V + L Q V EF E GID GG++KEF Q +V+E
Sbjct: 620 LKLTVRRDQLINDALIGLEMVAMSNPKDLKKQLVVEFVGEQGIDEGGVSKEFFQLIVEEI 679
Query: 611 FINQPFKLF-DTTSFNKLYPSKNVSP-QNLKYISFMGKILGKCLYENILVDVELADFFLK 668
F N F +F N ++ N +P +N + +G I+G +Y N+ + V +
Sbjct: 680 F-NPAFGMFIQQEETNNMW--FNATPFENGAQFTLIGIIIGLAIYNNVTLAVNFPMVVYR 736
Query: 669 KILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENEL----------AYMDLYFEVPDA 718
K++ F DL P Y++L +L+ ++ +Y D++ +V
Sbjct: 737 KLIGYCGT----FADLSDWSPALYKSLKSMLDYQGQDMEEVFEQTFKISYSDVFGDVVQH 792
Query: 719 PNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRM 778
L+ +G V Q N ++ S + LN + + F G + L++
Sbjct: 793 E------LVPNGQDVLVGQHNKELFVNLYSDFLLNTNIEQQFNAFRKGFEMVTDESPLKL 846
Query: 779 -FTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLK 836
F E++ L+ GS ++FD +L+ +T Y GG++E S IQ FW ++ + E++ K L+
Sbjct: 847 LFRPEEIEMLVCGS-REFDFVELENSTVYEGGYTEKSQYIQDFWSIVHAMPSEDKHKLLE 905
Query: 837 FVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTA 896
F P+ G L L I G ++DRLPT+ TC N+L LP+Y + L E+L+ A
Sbjct: 906 FTTGSARVPVGGLKCLRLL--ITRHGPDSDRLPTSHTCFNVLLLPEYSSREKLEERLMKA 963
Query: 897 INSDSRF 903
IN F
Sbjct: 964 INYSKGF 970
>Hs12232397 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 748
Score = 139 bits (350), Expect = 2e-32
Identities = 115/396 (29%), Positives = 189/396 (47%), Gaps = 33/396 (8%)
Query: 523 YFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQ 582
Y DL++ KI R P R + RE E++Y V +M + L +
Sbjct: 368 YKRDLVQKLKIL---RQELSQQQPQAGHCRIEVSREEIFEESYRQ---VMKMRPKDLWKR 421
Query: 583 FVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLF----DTTSFNKLYPSKNVSPQNL 638
+ +F E G+D GG+ +E+L L E +N + LF D ++ P V+P++L
Sbjct: 422 LMIKFRGEEGLDYGGVAREWLYLLSHE-MLNPYYGLFQYSRDDIYTLQINPDSAVNPEHL 480
Query: 639 KYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKL 698
Y F+G+I+G ++ +D F K++L ++ +D+ +DP+ + +L+ +
Sbjct: 481 SYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLG----KSITLDDMELVDPDLHNSLVWI 536
Query: 699 LEMSENELA-YMDLYFEVPDAPNGKRIP--LIKDGLSTKVTQKNVFEYITRISHYKLNLQ 755
LE N++ +D F V G+ I L +G S V ++N EY+ +++
Sbjct: 537 LE---NDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRF--- 590
Query: 756 LYTVTSRFIT---GLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSES 812
L + ++F+ G + +IP H L+ F EL+ +I G K D+ D K NT +
Sbjct: 591 LRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGK-IDVNDWKVNTRLKHCTPD 649
Query: 813 SVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNP-----LFGIRNAGDETDR 867
S ++ FW+ + F E R + L+FV PL+GF +L LF I T+
Sbjct: 650 SNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNN 709
Query: 868 LPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRF 903
LP A TC N + +P Y++Y L EKLLTAI F
Sbjct: 710 LPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGF 745
>Hs20550102 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 900
Score = 138 bits (347), Expect = 4e-32
Identities = 106/370 (28%), Positives = 181/370 (48%), Gaps = 27/370 (7%)
Query: 549 NRLRSTIRREHALEDAYNAYGAV--GEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTL 606
N+ +RR LED+Y V + K +L I EF E G+D GG+ +E+ +
Sbjct: 541 NKFEMKLRRATVLEDSYRRIMGVKRADFLKARLWI----EFDGEKGLDYGGVAREWFFLI 596
Query: 607 VQEGFINQPFKLFDTTSFN----KLYPSKNV-SPQNLKYISFMGKILGKCLYENILVDVE 661
+E F N + LF+ ++ + ++ P+ + + +L Y F+G++ G +Y L+D
Sbjct: 597 SKEMF-NPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLD-- 653
Query: 662 LADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG 721
FF++ + + + +D+ S+D EYY +L +LE EL DL F + + G
Sbjct: 654 --GFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTEL---DLRFIIDEELFG 708
Query: 722 K--RIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMF 779
+ + L G VT KN EYI + ++ ++ + F G +IP +++F
Sbjct: 709 QTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIF 768
Query: 780 TSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFV 838
EL+ L+ G D D+ D +++T Y G+S + IQ FW+ + E+R + L+FV
Sbjct: 769 DENELELLMCGLG-DVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFV 827
Query: 839 FSVPTAPLKGFHSLNPLFGIRNAGDET----DRLPTASTCINLLKLPDYQNYHTLREKLL 894
P+ GF L G ++ E ++LP A TC N L LP Y+++ L +KL
Sbjct: 828 TGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQ 887
Query: 895 TAINSDSRFE 904
AI + F+
Sbjct: 888 MAIENTQGFD 897
>CE25540 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 817
Score = 137 bits (345), Expect = 7e-32
Identities = 109/390 (27%), Positives = 179/390 (44%), Gaps = 47/390 (12%)
Query: 549 NRLRSTIRREHALEDAYNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLV 607
N ++ T+ R + ED++ + + +L IQF E G+D GG+ +E+ L
Sbjct: 437 NHVKITVSRNNVFEDSFQEIMRKNAVDLRRRLYIQFRGE----EGLDYGGVAREWFFLLS 492
Query: 608 QEGFINQPFKLFDTTSFN----KLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELA 663
E +N + LF N ++ P+ V+P +LKY ++G+ + D++ +
Sbjct: 493 HE-VLNPMYCLFMYAGNNNYSLQINPASFVNPDHLKYFEYIGRFIAMLKKPGNFDDLKFS 551
Query: 664 DFFL-----------------------KKILNVENNMNVPFNDLYSLDPEYYRNLMKLLE 700
D ++ KK+LN + + D+ +D E Y +LM + +
Sbjct: 552 DQYISFSPKNALFHGKFIYSGFTMPFYKKMLNKK----IVLKDIEQVDSEIYNSLMWIKD 607
Query: 701 MSENELAYMDLYFEVPDAPNG--KRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYT 758
+ +E M+LYF G K L + G VT++N EYI + ++ N +
Sbjct: 608 NNIDECD-MELYFVADYELLGELKTYELKEGGTEIAVTEENKLEYIELLVEWRFNRGVEQ 666
Query: 759 VTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQH 818
T F TG + + P W++ F EL+ L+ G + D D++D ++NT Y ++ S +
Sbjct: 667 QTKAFFTGFNSVFPLEWMQYFDERELELLLCGMQ-DVDVDDWQRNTVYRHYAPQSKQVTW 725
Query: 819 FWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSL-----NPLFGIRNAGDETDRLPTAST 873
FWQ + S E+R + L+FV P+ GF L LF I G E + LP + T
Sbjct: 726 FWQWVRSLDQEKRARLLQFVTGTCRVPVGGFSELMGSTGPQLFCIERVGKE-NWLPRSHT 784
Query: 874 CINLLKLPDYQNYHTLREKLLTAINSDSRF 903
C N L LP Y++Y L EKL AI F
Sbjct: 785 CFNRLDLPPYRSYDQLVEKLSMAIEMTEGF 814
>CE27342 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 810
Score = 137 bits (344), Expect = 1e-31
Identities = 115/402 (28%), Positives = 182/402 (44%), Gaps = 89/402 (22%)
Query: 555 IRREHALEDAYNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFIN 613
+ R+ ED+Y + + KL I+F FG E G+D GG+T+E+ L + F N
Sbjct: 441 VHRDTLFEDSYRHIMDKKDYDLRNKLWIEF---FG-ETGLDYGGVTREWFFLLSHQIF-N 495
Query: 614 QPFKLFDTTS---------FNKLYP----------------------------------- 629
+ LF+ ++ F KLY
Sbjct: 496 PYYGLFEYSATPFFWAIKCFLKLYKPTKKWRNFQILVINSNKQFLKKKNYRDNYTLQINP 555
Query: 630 -SKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLD 688
S+ +P++L Y F+G+I+G +Y L+D FF++ + + D+ S+D
Sbjct: 556 HSEACNPEHLSYFHFIGRIIGMAIYHGKLLDA----FFIRPFYKMMLGKKITLFDMESVD 611
Query: 689 PEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGK--RIPLIKDGLSTKVTQKNVFEYITR 746
EYY +L + + +N+ A ++L F + D+ G+ I LI +G + VT+ N EYI
Sbjct: 612 NEYYNSL---IYVKDNDPADLELTFSLDDSIFGETQNIELIPNGANVPVTEDNKEEYIEA 668
Query: 747 ISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY 806
+ +P++ LR+F + EL+ L+ G +K D++D K NT Y
Sbjct: 669 V-----------------------VPSNLLRLFDANELELLMCGLQK-IDVKDWKANTIY 704
Query: 807 -GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDE- 864
GG+ SS + +FW+ + SF E R + L+FV P+ GF L G++ E
Sbjct: 705 KGGYGPSSQVVHNFWKCILSFDNEMRARVLQFVSGTSRVPMNGFRELYGSNGLQKFTIER 764
Query: 865 ---TDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRF 903
D LP A TC N L LP Y + L+ KLLTAI + F
Sbjct: 765 WGSADMLPRAHTCFNRLDLPPYTTFKELKSKLLTAIENSEIF 806
>SPBP8B7.27 [O] KOG0941 E3 ubiquitin protein ligase
Length = 807
Score = 125 bits (313), Expect = 4e-28
Identities = 111/430 (25%), Positives = 192/430 (43%), Gaps = 46/430 (10%)
Query: 510 KFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPG----ENRLRSTIRREHALEDAY 565
++PF++ ++ L K+ I +R +FF E L +RR+ LED+
Sbjct: 389 QYPFLLSMGAKISILQ-LDARRKMEIKAREAFFSSILSKMNVEPYLMIRVRRDRLLEDSL 447
Query: 566 NAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTT--S 623
+ F++ L ++F+ E GID GG+ +E+L L ++ F + F LF S
Sbjct: 448 RQINDRNKDFRKALKVEFLGE----EGIDAGGLKREWLLLLTRKVF-SPEFGLFVNCEES 502
Query: 624 FNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFND 683
N L+ + + + + Y G ++G ++ +I +DV++ F KK+L + + FND
Sbjct: 503 SNYLWFNYSHRSKEIDYYHMSGILMGIAIHNSINLDVQMPRAFYKKLLQLP----LSFND 558
Query: 684 LYSLDPEYYRNLMKLLEMSENELAYMDLYFEVP-DAPNGKRIPLIKDGLST-KVTQKNVF 741
L P YR L +LL + L F + A G R +K+G S V +N
Sbjct: 559 LDDFQPSLYRGLKELLLFEGDVKNTYGLNFTINLKAVEGFRTVELKEGGSELSVDNENRK 618
Query: 742 EYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLK 801
EY+ R Y LN + S F G + + + +F E+ LI GSE+ D E LK
Sbjct: 619 EYVLRYVDYLLNTTVKKQFSAFFDGFMKVCGGNAISLFQDNEISKLIRGSEEVIDWELLK 678
Query: 802 KNTSYGGFSESSVT--------------------------IQHFWQVLSSFTPEERRKFL 835
Y + +++++ I FW ++S ++ + ++ FL
Sbjct: 679 NVCVYDFYDQNAISNSISESEPSMTASKYLCHSFVSKRKIILWFWDLISHYSLKMQKLFL 738
Query: 836 KFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLT 895
FV P G H+ + G ++D+LP + TC N L + +Y + L++KL T
Sbjct: 739 IFVTGSDRIPATGAHNFQLRISV--LGPDSDQLPISHTCFNHLCIWEYSSREKLKKKLDT 796
Query: 896 AINSDSRFEL 905
A+ + F +
Sbjct: 797 ALLETNGFNI 806
>7296017 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 971
Score = 125 bits (313), Expect = 4e-28
Identities = 108/365 (29%), Positives = 172/365 (46%), Gaps = 28/365 (7%)
Query: 555 IRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQ 614
++RE LE + A G + G F F E GID GG+ +E+ + LV +
Sbjct: 611 VQREKILESSMKA--VKGFSVSDWCG-NFEVTFQGEQGIDWGGLRREWFE-LVCSALFDA 666
Query: 615 PFKLFDT--TSFNKLYPSKNVSPQNLK--YISFMGKILGKCLYENIL-------VDVELA 663
LF T L P +LK + F GK++GKCL+E+ L V +
Sbjct: 667 RGGLFCTFHDKHQALVHPNPTRPAHLKLKHFEFAGKMVGKCLFESALGGTYRQLVRARFS 726
Query: 664 DFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMK-LLEMSENELAYMDLYF--EVPDAPN 720
FL +++ + V + DP+ Y + +K +L+ + ++LYF E+ D+ +
Sbjct: 727 RSFLAQLIG----LRVHYKYFEQDDPDLYLSKIKYILDTDLDATDTLELYFVEEMYDSSS 782
Query: 721 G---KRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLR 777
G K I LI +G T+VT +Y+ ++ +L + F+ GL+ +IP + L
Sbjct: 783 GQLSKTIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLS 842
Query: 778 MFTSYELKTLISGSEKDFDLEDLK-KNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLK 836
+F EL+ L+ G+ ++ + D K + + G +E + FW +S+F+ E + L+
Sbjct: 843 IFDENELELLMCGT-GEYSISDFKAHHIANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQ 901
Query: 837 FVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTA 896
F P GF LNP F I A LPTA TC N L LPDY++Y + LL A
Sbjct: 902 FTTGCSQLPPGGFQELNPQFQI-TAAPTFGNLPTAHTCFNQLCLPDYESYEQFEKSLLLA 960
Query: 897 INSDS 901
I+ S
Sbjct: 961 ISEGS 965
>Hs7662052 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 823
Score = 122 bits (305), Expect = 3e-27
Identities = 96/327 (29%), Positives = 151/327 (45%), Gaps = 22/327 (6%)
Query: 587 FGPEAGIDGGGITKEFLQTLVQEGF--INQPFKLFDTTSFNKLYPSKNVSPQ-NLKYISF 643
F E +D GG +E+ + + + F NQ F F + ++P+ N LK F
Sbjct: 495 FQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKMYEF 554
Query: 644 MGKILGKCLYENIL-------VDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLM 696
G+++GKCLYE+ L V FL +I+ + + D DPE+Y++ +
Sbjct: 555 AGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETD----DPEFYKSKV 610
Query: 697 KLL---EMSENELAYMDLYFEVPDAPNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLN 753
+ +MSE EL + + + K + L+ G T VT N Y+ ++ Y+L
Sbjct: 611 CFILNNDMSEMELVFAEEKYN-KSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLA 669
Query: 754 LQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY--GGFSE 811
Q+ F+ GL+ ++P + L +F EL+ L+ G+ D + D K + G +
Sbjct: 670 SQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGT-GDISVSDFKAHAVVVGGSWHF 728
Query: 812 SSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTA 871
++ FW V+SS T EE + L+F P GF +L P F I A LPTA
Sbjct: 729 REKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQI-IAAPTHSTLPTA 787
Query: 872 STCINLLKLPDYQNYHTLREKLLTAIN 898
TC N L LP Y +Y + L AI+
Sbjct: 788 HTCFNQLCLPTYDSYEEVHRMLQLAIS 814
>7291075 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 388
Score = 120 bits (300), Expect = 1e-26
Identities = 101/358 (28%), Positives = 170/358 (47%), Gaps = 23/358 (6%)
Query: 559 HALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKL 618
H LEDA+ + + ++ + + + E G+D GG ++EF L +E F N + L
Sbjct: 38 HLLEDAFRRIMSANKKDLQRGRLAVL--WDTEEGLDYGGPSREFFFLLSRELF-NPYYGL 94
Query: 619 FDTTSFNKLYPSKNVSPQNL------KYISFMGKILGKCLYENILVDVELADFFLKKILN 672
F+ ++ N Y + VSP + + F G++LG L L+D F K +L
Sbjct: 95 FEYSA-NDTY-TVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLR 152
Query: 673 VENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGKRIP--LIKDG 730
+ V +DL SLD E++++L + + + L F V + G + L G
Sbjct: 153 LP----VALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVTEELLGSVVDRELKPGG 208
Query: 731 LSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISG 790
+ + +KN EY+ R+ ++L + T + G +I + + +F + EL+ +I+G
Sbjct: 209 KNIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAG 268
Query: 791 SEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGF 849
+ + D D + NT Y G+ ++ I FWQV+ F+ E+R + L+FV + P +GF
Sbjct: 269 TA-EIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGF 327
Query: 850 HSLNPLFGIR----NAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRF 903
+L G R + + LP A TC N L LP Y L EKLL A+ + F
Sbjct: 328 SALRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTF 385
>Hs10863903_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 650
Score = 120 bits (300), Expect = 1e-26
Identities = 125/455 (27%), Positives = 197/455 (42%), Gaps = 74/455 (16%)
Query: 513 FMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRLRSTIRREHALEDAYNAYGAVG 572
F + F+R L++ + S + V P +R + T+ RE L+ A + +G
Sbjct: 209 FYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLG 268
Query: 573 EMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQE----------------------- 609
+ L IQ+ NE G G G T EF + QE
Sbjct: 269 SS-RAMLEIQYENEVGT-----GLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQ 322
Query: 610 ---GFINQPFKLFDTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFF 666
+I LF F + +++ +K+ F+GK++ K + + LVD+ L F
Sbjct: 323 EGTKYIQNLQGLF-ALPFGRTAKPAHIAKVKMKF-RFLGKLMAKAIMDFRLVDLPLGLPF 380
Query: 667 LKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEM-------------SENELAY----- 708
K +L E ++ +DL+ +DP R++ L ++ ++ L Y
Sbjct: 381 YKWMLRQETSLTS--HDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETL 438
Query: 709 ---------MDLYFEVPDAPNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTV 759
+ L F +P PN I L K G VT N+ EY+ + + LN +
Sbjct: 439 TMNGCSVEDLGLDFTLPGFPN---IELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQ 495
Query: 760 TSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKD-FDLEDLKKNTSYG-GFSESSVTIQ 817
F G + P L+ F EL L+ GS+ D +D + L + G++ S ++
Sbjct: 496 FDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVK 555
Query: 818 HFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLN-PLFGIRNAGDET----DRLPTAS 872
+++LSSF E++R FL+FV P P+ GF SLN PL +R + T D LP+
Sbjct: 556 FLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVM 615
Query: 873 TCINLLKLPDYQNYHTLREKLLTAINSDSR-FELS 906
TC+N LKLPDY + +REKLL A + F LS
Sbjct: 616 TCVNYLKLPDYSSIEIMREKLLIAAREGQQSFHLS 650
>CE01588 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 889
Score = 117 bits (292), Expect = 1e-25
Identities = 101/376 (26%), Positives = 163/376 (42%), Gaps = 36/376 (9%)
Query: 547 GENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTL 606
G +RL + R+ L+DA+ V +K + F E +D GG+++EF L
Sbjct: 516 GPSRLCWKVSRDRLLDDAFRIILNVDPFVLKKSRLHI--RFEGELALDYGGLSREFFILL 573
Query: 607 VQEGFI--NQPFKLFDTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELAD 664
+E F N F+ +L P + + K++ G++L + +DV +
Sbjct: 574 SRELFHPKNGYFEYEGNDYHLQLRPRGCETEKEKKWLILCGRVLALAVIHRCYIDVFFTN 633
Query: 665 FFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNGK-- 722
F K + V D D E+Y+++ LLE N++ +++ F NGK
Sbjct: 634 VFYKSL----QKRPVTLMDFKESDAEFYKSMNWLLE---NDVVDLEMSFVYSSMVNGKVS 686
Query: 723 ---------------RIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGL 767
L+ G S VT+ N E+I + K + +T
Sbjct: 687 DLTLSSIVSVALQLAEQELVPGGESQMVTEANKAEFIDLMCQKKAIRGVEKPLEILLTSF 746
Query: 768 SYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSF 826
+ ++ + L S +LK ++SGS + DL D + NT Y GG+S+ + ++ FW+V+ +
Sbjct: 747 NQILNDNLLNSLESSDLKRILSGS-LELDLNDWRTNTIYKGGYSDCHIVVEWFWEVIETM 805
Query: 827 TPEERRKFLKFVFSVPTAPLKGFHSLN-----PLFGIRNAGDETDRLPTASTCINLLKLP 881
T +ER L FV + P +GF +L F I GD T P A TC N L+LP
Sbjct: 806 TNQERFDLLLFVTGSSSVPFEGFSALRGNEEISKFCIEKWGDATS-FPRAHTCFNRLQLP 864
Query: 882 DYQNYHTLREKLLTAI 897
Y L+ KL AI
Sbjct: 865 SYNTKQQLKSKLQQAI 880
>YJR036c [O] KOG0941 E3 ubiquitin protein ligase
Length = 892
Score = 116 bits (291), Expect = 1e-25
Identities = 97/361 (26%), Positives = 173/361 (47%), Gaps = 43/361 (11%)
Query: 572 GEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGF------------INQPFKLF 619
G++ K L I+FVNE GID GG+ KE+ L + F ++ +
Sbjct: 543 GDLLKS-LRIEFVNE----PGIDAGGLRKEWFFLLTKSLFNPMNGLFIYIKESSRSWFAI 597
Query: 620 DTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNV 679
D +F+K SK + Q Y F G ++G ++ + ++D++ KK+ + +
Sbjct: 598 DPPNFDK---SKGKNSQLELYYLF-GVVMGLAIFNSTILDLQFPKALYKKLCSEP----L 649
Query: 680 PFNDLYSLDPEYYRNLMKLLEMSEN----------ELAYMDLYFEVPDAPNGKR---IPL 726
F D L PE RNL+K+L +E+ E Y + + + D+ + K + L
Sbjct: 650 SFEDYSELFPETSRNLIKMLNYTEDNFEDVFSLTFETTYRNNNWILNDSKSSKEYVTVEL 709
Query: 727 IKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIP-AHWLRMFTSYELK 785
++G + +TQ N E++ + + L + ++F++G + + +++F S EL+
Sbjct: 710 CENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKLFNSEELE 769
Query: 786 TLISGSEKD--FDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVP 842
L+ G E+ FD + L+ T Y GGFS+ S + FW+++ S+ ++K L+FV +
Sbjct: 770 RLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASD 829
Query: 843 TAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSR 902
P G ++ + + D +D LP A TC N + L +Y + L KLL AIN
Sbjct: 830 RIPATGISTIPFKISLLGSHD-SDDLPLAHTCFNEICLWNYSSKKKLELKLLWAINESEG 888
Query: 903 F 903
+
Sbjct: 889 Y 889
>Hs8923590 [O] KOG0941 E3 ubiquitin protein ligase
Length = 379
Score = 116 bits (291), Expect = 1e-25
Identities = 97/365 (26%), Positives = 170/365 (46%), Gaps = 22/365 (6%)
Query: 545 FPGENRLRSTIRREHALEDAYNAYG-AVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFL 603
FP R +RR ++DA A F + L ++F+NE PE+G G++ EF
Sbjct: 23 FPPSPRFILRVRRSRLVKDALRQLSQAEATDFCKVLVVEFINEICPESG----GVSSEFF 78
Query: 604 QTLVQEGFINQP---FKLFDTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDV 660
+ +E + +P ++ +P+K P+ +Y F G + G L+ + ++
Sbjct: 79 HCMFEE--MTKPEYGMFMYPEMCSCMWFPAKP-KPEKKRYFLF-GMLCGLSLFNLNVANL 134
Query: 661 ELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELA-YMDLYFEVPDAP 719
KK+L+ + ++ DL L P ++L ++L+ + +++ + + F +
Sbjct: 135 PFPLALYKKLLDQKPSLE----DLKELSPRLGKSLQEVLDDAADDIGDALCIRFSIHWDQ 190
Query: 720 NGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMF 779
N + LI +G+S V Q N +Y+++ Y N+ + V F G + LR F
Sbjct: 191 ND--VDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHF 248
Query: 780 TSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQVLSSFTPEERRKFLKFV 838
EL T I G+ D+D + ++N+ Y G+ +S TIQ FW+ T +E++KFL F+
Sbjct: 249 YPEELMTAIIGN-TDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFL 307
Query: 839 FSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
+G + +F E D PT+ TC N+L LP Y + E L AIN
Sbjct: 308 TGRDRLHARGIQKMEIVFRCPETFSERDH-PTSITCHNILSLPKYSTMERMEEALQVAIN 366
Query: 899 SDSRF 903
++ F
Sbjct: 367 NNRGF 371
>Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1024
Score = 116 bits (291), Expect = 1e-25
Identities = 124/491 (25%), Positives = 202/491 (40%), Gaps = 41/491 (8%)
Query: 431 FWDLVPEEMHNLNIKKEILEFEQYYRAYLVRFEEMDLNEDEMFDKKKFIDQNIKGQYLDD 490
+WD EE N+ E+L+ + E DE+ + F + + +YL
Sbjct: 556 YWDESAEENGNVQALLEMLKKLHRVNQVKCQLPESIFQVDELLHRLNFFVEVCR-RYLWK 614
Query: 491 LXXXXXXXXXXXXXLELLFKFPFMIKFFERVDYFND----LIEADKIRIYSRNSFF---- 542
+ + FPF+ ++ + IE+ K + Y R++
Sbjct: 615 MTVDASENVQCCV---IFSHFPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEER 671
Query: 543 -GVFPGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKE 601
F T+RR H +ED N + + E L + F E G D GG+ KE
Sbjct: 672 ESEFALRPTFDLTVRRNHLIEDVLNQ---LSQFENEDLRKELWVSFSGEIGYDLGGVKKE 728
Query: 602 FLQTLVQEGFINQPFKLFDTTSFNKLYPSKN------VSPQ-NLKYISFMGKILGKCLYE 654
F L E I + +F +YP V P+ K F G + G L+
Sbjct: 729 FFYCLFAE-MIQPEYGMF-------MYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFN 780
Query: 655 NILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLE-MSENELAYMDLYF 713
+ ++ KK+L+ ++ DL L P+ +NL LL+ +N ++F
Sbjct: 781 CNVANLPFPLALFKKLLDQMPSLE----DLKELSPDLGKNLQTLLDDEGDNFEEVFYIHF 836
Query: 714 EVPDAPNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPA 773
V N LI +G S V Q N +Y+++ +Y N + V F G M
Sbjct: 837 NVHWDRNDTN--LIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDE 894
Query: 774 HWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYG-GFSESSVTIQHFWQVLSSFTPEERR 832
+++F ELK +I G+ D+D + +KN Y G++ S TI FW+ T EE++
Sbjct: 895 DIIKLFHPEELKDVIVGNT-DYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKK 953
Query: 833 KFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREK 892
KFL F+ +K +++ F + +E D + A TC ++L LP Y T+ E
Sbjct: 954 KFLVFLTGTDRLQMKDLNNMKITFCCPESWNERDPI-RALTCFSVLFLPKYSTMETVEEA 1012
Query: 893 LLTAINSDSRF 903
L AIN++ F
Sbjct: 1013 LQEAINNNRGF 1023
>7302746 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 1017
Score = 115 bits (288), Expect = 3e-25
Identities = 97/373 (26%), Positives = 156/373 (41%), Gaps = 52/373 (13%)
Query: 546 PGENRLRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQT 605
P R + R E++Y + +M + + + + +F E G+D GG+ +E+L
Sbjct: 679 PQSGHCRLEVSRNEIFEESYRL---IMKMRAKDMRKRLMVKFKGEEGLDYGGVAREWLHL 735
Query: 606 LVQEGFINQPFKLF----DTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVE 661
L +E +N + LF D ++ P V+P +L Y F+
Sbjct: 736 LSRE-MLNPQYGLFQYSRDDHYTLQINPDSGVNPDHLSYFHFL----------------- 777
Query: 662 LADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG 721
N + D+ +DP+ +R+L +LE N ++ F V + G
Sbjct: 778 -------------LNKPITLGDIEGVDPDLHRSLTWMLE--SNISGIIESTFSVENNSFG 822
Query: 722 KRI--PLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMF 779
+ L G S VT++N EY+ +Y+ + G +IP+H LR F
Sbjct: 823 ALVVHELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPF 882
Query: 780 TSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVF 839
EL+ L+ G D+ D + NT + + + FWQV+ S++ E R + L+FV
Sbjct: 883 DERELE-LVIGGISSIDVNDWRNNTRLKHCTNETTQVLWFWQVVESYSSEMRARLLQFVT 941
Query: 840 SVPTAPLKGFHSLN--------PLFGIRNAGD-ETDRLPTASTCINLLKLPDYQNYHTLR 890
PL+GF +L LF I D T LP A TC N + LP Y+ Y L
Sbjct: 942 GSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLPPYETYQLLC 1001
Query: 891 EKLLTAINSDSRF 903
+KL A+ F
Sbjct: 1002 DKLTQAVEETCGF 1014
>Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1050
Score = 108 bits (271), Expect = 3e-23
Identities = 86/324 (26%), Positives = 152/324 (46%), Gaps = 12/324 (3%)
Query: 587 FGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDTTSFNKLYPSKNVSPQNLKYISFMGK 646
F E +D GG+TKEF L++E +N + +F + L + + +G
Sbjct: 735 FDGEEAVDAGGVTKEFFLLLLKE-LLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGI 793
Query: 647 ILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEM-SENE 705
G +Y + +VD+ KK+LNV+ + DL L P R+L +LL+ E+
Sbjct: 794 TCGLAIYNSTVVDLHFPLALYKKLLNVKPGLE----DLKELSPTEGRSLQELLDYPGEDV 849
Query: 706 LAYMDLYFEVPDAPNG--KRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRF 763
L F + G ++ LI G + V + N E++ +Y + ++ + F
Sbjct: 850 EETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAF 909
Query: 764 ITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY-GGFSESSVTIQHFWQV 822
+G + L +F EL+ ++ G+ +++ E+L++ Y G +S + T++ FW+
Sbjct: 910 SSGFLKVCGGKVLELFQPSELRAMMVGNS-NYNWEELEETAIYKGDYSATHPTVKLFWET 968
Query: 823 LSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPD 882
F E+++KFL F+ P+ G SL + +G+E LP A TC NLL LP
Sbjct: 969 FHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEE--YLPVAHTCYNLLDLPK 1026
Query: 883 YQNYHTLREKLLTAINSDSRFELS 906
Y + L +L A+++ F L+
Sbjct: 1027 YSSKEILSARLTQALDNYEGFSLA 1050
>SPAC12B10.01c [O] KOG0170 E3 ubiquitin protein ligase
Length = 400
Score = 105 bits (262), Expect = 3e-22
Identities = 97/353 (27%), Positives = 162/353 (45%), Gaps = 43/353 (12%)
Query: 586 EFGPEAGIDGGGITKEFLQTLVQEGFIN--------QPFKLFDTTSFNKLYPSK----NV 633
E+ E G G G T EF ++ +E +N QP F + L+PS
Sbjct: 59 EYEDEVG-SGLGPTLEFYTSVSKEFTLNSLDIWRNDQPNSKF-VYQASGLFPSPIPLLGS 116
Query: 634 SPQNLKYISF---MGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPE 690
SP+N + IS +G+ + + +Y++ ++ ++ F + N+ + + + +D
Sbjct: 117 SPENERKISLFFALGQFVARSIYDSRIISIQFNPLFFAR------NIPLTISSVAKVDKG 170
Query: 691 YYRNLMKLLEM--------SENELAYMDLY--FEVPDAPNGKRIPLIKDGLSTKVTQKNV 740
+L L ++ +E ++ DL+ F +P P+ I LI DG ST VT NV
Sbjct: 171 LANSLRYLEKLIPGKNPTNAETDIKLEDLHLDFTLPGFPS---IELIPDGASTPVTTFNV 227
Query: 741 FEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDL 800
+Y+ + Y + + F G S + P L++ T +EL TL ++D+ L
Sbjct: 228 SDYLNYVIDYTVGKGVQQQLEAFQNGFSSVFPYTSLQVLTEHELVTLFGTVDEDWSYATL 287
Query: 801 KKN-TSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLN-PLFGI 858
K+ + G++ S TIQ ++S +E+R FL+F+ P+ GF LN PL +
Sbjct: 288 MKSIVADHGYTMESPTIQRLLTLMSQMNFQEQRDFLQFITGSRKLPIGGFAGLNPPLTVV 347
Query: 859 RNAGD----ETDRLPTASTCINLLKLPDYQNYHTLREKLLTAI-NSDSRFELS 906
R + D LP+ TC+N LKLP+Y + L +L AI F LS
Sbjct: 348 RRLNEPPYVPDDYLPSVMTCVNYLKLPEYSSSEVLGSRLSKAILEGQGSFHLS 400
>At4g12570 [O] KOG0940 Ubiquitin protein ligase RSP5/NEDD4
Length = 873
Score = 104 bits (260), Expect = 5e-22
Identities = 96/361 (26%), Positives = 153/361 (41%), Gaps = 26/361 (7%)
Query: 555 IRREHALEDAYN-AYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFIN 613
I R + L +++ GA E L ++F NE EA G G+ +E+ + QE F N
Sbjct: 515 IDRSNLLSESFEYIVGASPEALHGGLFMEFKNE---EA--TGPGVLREWFYLVCQEIF-N 568
Query: 614 QPFKLF--DTTSFNKLYPS--KNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKK 669
LF F + P+ V P + + F G+++ L + V V F +
Sbjct: 569 PKNTLFLRSADDFRRFSPNPASKVDPLHPDFFEFTGRVIALALMHKVQVGVLFDRVFFLQ 628
Query: 670 ILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSE---NELAYMDLYFEVPDAPNGKR--I 724
+ ++ + D+ D Y + ++LEM + A + L F + GKR I
Sbjct: 629 LAGLK----ISLEDIKDTDRIMYNSCKQILEMDPEFFDSNAGLGLTFVLETEELGKRDTI 684
Query: 725 PLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMI-----PAHWLRMF 779
L DG V KN +Y+ + + + +F G + M+ P + +
Sbjct: 685 ELCPDGKLKAVNSKNRKQYVDLLIERRFATPILEQVKQFSRGFTDMLSHSVPPRSFFKRL 744
Query: 780 TSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSSFTPEERRKFLKFVF 839
+L ++ G E ++D K +T Y GF E+ I FW++L T EE+R L F
Sbjct: 745 YLEDLDGMLRGGENPISIDDWKAHTEYNGFKETDRQIDWFWKILKKMTEEEQRSILFFWT 804
Query: 840 SVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINS 899
S P++GF L+ I + DRLP + TC L +P Y TL E+ L I
Sbjct: 805 SNKFVPVEGFRGLSSKLYIYRLYEANDRLPLSHTCFYRLCIPRYPTI-TLMEQRLRLIAQ 863
Query: 900 D 900
D
Sbjct: 864 D 864
>CE29116 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1019
Score = 104 bits (259), Expect = 7e-22
Identities = 101/366 (27%), Positives = 161/366 (43%), Gaps = 23/366 (6%)
Query: 551 LRSTIRREHALEDAYNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEG 610
L T+RRE + D N + E +K VN G +A D GG+ KEF LV
Sbjct: 667 LELTVRREFIVSDTMNQMAGLSESDLQKP--LKVNIAGEDAD-DAGGVRKEFF-ILVMRK 722
Query: 611 FINQPFKLFDTTSFNKLYPSKNVSPQNLKYISF--MGKILGKCLYENILVDVELADFFLK 668
+ + +F + L + + F +G+++G +Y + +V K
Sbjct: 723 ILQSDYGMFSEDEESHLVWFSGLPSEFCDREQFHQLGRLVGLSIYNHSIVPFPFPLALYK 782
Query: 669 KILNVENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELA-YMDLYFEVPDAPNGKR--IP 725
+L+ ++ DL L P + L LL E+++ L F + G+
Sbjct: 783 YLLDTPPDLE----DLCELSPSEGKGLKMLLSYEEDDVEDVFGLNFCISFNILGETHTTE 838
Query: 726 LIKDGLSTKVTQKNVFEYITRISHYKLNL----QLYTVTSRFITGLSYMIPAHWLRMFTS 781
L+ G VT N EY+ H++L L ++ F G S + + LR F
Sbjct: 839 LLSGGTEKPVTNANRDEYVRLYVHHRLELGYNGEIAQQALLFRKGFSESLHSRTLRFFQP 898
Query: 782 YELKTLISGSEKDFDLEDLKKNTSYGG-FSESSVTIQHFWQVLSSFTPEERRKFLKFVFS 840
ELK +I G+E ++D + + Y G +S S TIQ FW+ + T +ERRKFL+F+
Sbjct: 899 CELKEMIVGNE-NYDWNEFRDILMYRGEYSSSHPTIQAFWKAFFALTDDERRKFLQFLTG 957
Query: 841 VPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSD 900
P+ G+ L+ I+ + E+ LP A TC NLL LP+ + L +L +I
Sbjct: 958 STRIPVSGWEELHA--AIQPSAPES--LPVAHTCFNLLDLPNIADDVELLRRLRISIEHT 1013
Query: 901 SRFELS 906
F L+
Sbjct: 1014 EGFTLA 1019
>Hs4758520 [S] KOG1426 FOG: RCC1 domain
Length = 4834
Score = 102 bits (253), Expect = 3e-21
Identities = 82/270 (30%), Positives = 131/270 (48%), Gaps = 14/270 (5%)
Query: 634 SPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYR 693
+P + F+G +LG + + + LA+ K++ M++ DL +D ++
Sbjct: 4526 APVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAG----MSLTIADLSEVDKDFIP 4581
Query: 694 NLMKLL--EMSENELAYMDLYFEVPDAPNGKRIPLIKDGLSTKVTQKNVFEYITRISHYK 751
LM + E + E M L F VP A +G+ I L T +T N EY+ +Y+
Sbjct: 4582 GLMYIRDNEATSEEFEAMSLPFTVPSA-SGQDIQL--SSKHTHITLDNRAEYVRLAINYR 4638
Query: 752 LNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSE 811
L+ + + G++ ++P L +FT YEL+T++ GS D L LK +Y G
Sbjct: 4639 LH-EFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSP-DIPLHLLKSVATYKGIEP 4696
Query: 812 SSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAP--LKGFHSLNPLFGIRNAGDETDR-L 868
S+ IQ FW+V+ SF+ ER FL+FV+ P + F + + + + + D L
Sbjct: 4697 SASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFL 4756
Query: 869 PTASTCINLLKLPDYQNYHTLREKLLTAIN 898
P + TC LLKLP Y L EKL AI+
Sbjct: 4757 PESYTCFFLLKLPRYSCKQVLEEKLKYAIH 4786
>Hs4557026 [S] KOG1426 FOG: RCC1 domain
Length = 4861
Score = 101 bits (251), Expect = 6e-21
Identities = 81/325 (24%), Positives = 147/325 (44%), Gaps = 22/325 (6%)
Query: 590 EAGIDGGGITKEFLQTLVQE---GFINQPFKLFDTTS---FNK---LYPSKNVSPQNLKY 640
E D GG+ + + + QE G ++ + T+ +N+ L+ ++L
Sbjct: 4519 EGADDAGGVFDDTITEMCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQ 4578
Query: 641 ISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLE 700
F+G ++G + +D+ LA K++ V + DL +D Y + L +L
Sbjct: 4579 FKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVP----LTLEDLEEVDLLYVQTLNSILH 4634
Query: 701 MSENELAYMDLYFEVP------DAPNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNL 754
+ ++ + + +P + +GK +P+I G S +T N EY+ R Y+L+
Sbjct: 4635 IEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLH- 4693
Query: 755 QLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSV 814
++ + G+S+++P L + T+ +L+ ++ G + +E LKK Y E
Sbjct: 4694 EMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMP-EISVEVLKKVVRYREVDEQHQ 4752
Query: 815 TIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTC 874
+Q FW L F+ EER F++FV P ++ F I D LPT+ TC
Sbjct: 4753 LVQWFWHTLEEFSNEERVLFMRFVSGRSRLP-ANTADISQRFQIMKVDRPYDSLPTSQTC 4811
Query: 875 INLLKLPDYQNYHTLREKLLTAINS 899
L+LP Y + + E+L AIN+
Sbjct: 4812 FFQLRLPPYSSQLVMAERLRYAINN 4836
>7292061 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1057
Score = 99.4 bits (246), Expect = 2e-20
Identities = 91/356 (25%), Positives = 161/356 (44%), Gaps = 18/356 (5%)
Query: 555 IRREHALEDAYNAYGAVGEM-FKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFIN 613
+ RE+ ++D+ + K+ L I+F G EA D GG+ KEF L+++ ++
Sbjct: 714 VTRENLVQDSLRELQHYSQSDLKKPLKIKF---HGEEAE-DAGGVRKEFFMLLLKD-LLD 768
Query: 614 QPFKLFDTTSFNKLYPSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNV 673
+ +F ++L +++ + +G + G +Y ++++ KK+L
Sbjct: 769 PKYGMFKEYEQSRLLWFADLTFETENMYFLIGVLCGLAIYNFTIINLPFPLALFKKLLGK 828
Query: 674 ENNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYM-DLYFEVPDAPNGKRIP--LIKDG 730
V +DL L P ++ LL+ ++ + DL FE+ G+ L +G
Sbjct: 829 P----VDLSDLRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKCLKPNG 884
Query: 731 LSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISG 790
VT +N E++ + N + + F G + + +F EL ++ G
Sbjct: 885 NEIAVTLENRQEFVDLYVDFVFNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVG 944
Query: 791 SEKDFDLEDLKKNTSYG-GFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGF 849
+E D+D + L+ N Y G++ TI+ FW+V+ + E++ FL F+ P++G
Sbjct: 945 NE-DYDWQALQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIPIQGM 1003
Query: 850 HSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFEL 905
+L I+ DE LP A TC NLL LP Y+ L+ KLL AI F L
Sbjct: 1004 KALK--LTIQPTPDERF-LPVAHTCFNLLDLPRYKTKERLKYKLLQAIQQTQGFSL 1056
>At5g02880_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 628
Score = 95.5 bits (236), Expect = 3e-19
Identities = 111/447 (24%), Positives = 183/447 (40%), Gaps = 59/447 (13%)
Query: 508 LFKFPFMIKFFERVDYFNDLIEADKIRIYSRNSFFGVFPGENRL---RSTIRREHALEDA 564
LF F K+F + + I + S N P L + RE+ LE A
Sbjct: 193 LFSFEAKSKYFRLAAFGSQKIRHHPQHLSSSNVHGEARPVTGSLPRKKFLACRENILESA 252
Query: 565 YNAYGAVGEMFKEKLGIQFVNEFGPEAGIDGGGITKEFLQTLVQEGFINQPFKLFDT--- 621
G K + +++ E G G G T EF TLV F N ++
Sbjct: 253 AKMMELYGNQ-KVVIEVEYSEEVGT-----GLGPTLEFY-TLVSRAFQNPDLGMWRNDCS 305
Query: 622 -------------TSFNKLYP----SKNVSPQNLKYISFMGKILGKCLYENILVDVELAD 664
S + L+P + + L+ +G ++ K L + ++D+ L+
Sbjct: 306 FIVGKPVEHSGVLASSSGLFPRPWSGTSTTSDVLQKFVLLGTVVAKALQDGRVLDLPLSK 365
Query: 665 FFLKKILNVENNMNVPFNDLYSLDPEYYRNLMKLLEM-----------SENELAYMDLYF 713
F K IL E + D++ +DPE + L++L + ++ A DL F
Sbjct: 366 AFYKLILGQE----LSSFDIHFVDPELCKTLVELQALVRRKKLFAEAHGDSGAAKCDLSF 421
Query: 714 ---EVPDA------PNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFI 764
++ D P L + V N+ EYI I + + + F
Sbjct: 422 HGTKIEDLCLEFALPGYTDYDLAPYSANDMVNLDNLEEYIKGIVNATVCNGIQKQVEAFR 481
Query: 765 TGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYG-GFSESSVTIQHFWQVL 823
+G + + LR+F EL+T++ G F + ++ + + G++ SS +++ Q+L
Sbjct: 482 SGFNQVFSIEHLRIFNEEELETMLCGECDLFSMNEVLDHIKFDHGYTSSSPPVEYLLQIL 541
Query: 824 SSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGI--RNAGDETDR-LPTASTCINLLKL 880
F E++R FL+FV P P G SL+P I ++ D +D LP+ TC N LKL
Sbjct: 542 HEFDREQQRAFLQFVTGSPRLPHGGLASLSPKLTIVRKHGSDSSDTDLPSVMTCANYLKL 601
Query: 881 PDYQNYHTLREKLLTAI-NSDSRFELS 906
P Y + ++EKL+ AI F LS
Sbjct: 602 PPYSSKEKMKEKLIYAITEGQGSFHLS 628
>Hs15147337 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2799
Score = 95.1 bits (235), Expect = 4e-19
Identities = 79/285 (27%), Positives = 142/285 (49%), Gaps = 23/285 (8%)
Query: 629 PSKNVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLD 688
P KN + L +G+ILG CL +N L + L +K +L + N ++D D
Sbjct: 2518 PGKNTEAR-LNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVN----WHDFAFFD 2572
Query: 689 PEYYRNLMKLLEMSENE-----LAYMDLYFEVP--DAPNGKRIPLIKDGLSTKVTQKNVF 741
P Y +L +L+ S++ + MDL F + G ++ LI +G++ VT +NV+
Sbjct: 2573 PVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVY 2632
Query: 742 EYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLK 801
EY+ + + +++ + GL ++P + L T+ + + L++G + +++ L
Sbjct: 2633 EYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCG-EVNVQMLI 2691
Query: 802 KNTSY----GGFSESSVTIQH-FWQVLSSFTPEERRKFLKFVFSVPTAPL--KGFHSLNP 854
TS+ G +E + + FW ++ + ER+ + F S P+ P +GF + P
Sbjct: 2692 SFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPM-P 2750
Query: 855 LFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINS 899
IR D+ LPTA+TCI+ L +P Y + L++KLL AI +
Sbjct: 2751 SITIRPPDDQ--HLPTANTCISRLYVPLYSSKQILKQKLLLAIKT 2793
>Hs20474127 [O] KOG0941 E3 ubiquitin protein ligase
Length = 218
Score = 93.2 bits (230), Expect = 2e-18
Identities = 65/219 (29%), Positives = 104/219 (46%), Gaps = 5/219 (2%)
Query: 689 PEYYRNLMKLLEMSENELAYMDLYFEVPDAPNG--KRIPLIKDGLSTKVTQKNVFEYITR 746
PE L +LL N F+V G K L G VT +N EY+
Sbjct: 2 PELAHGLSELLSHEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQL 61
Query: 747 ISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSY 806
+ + LN +Y + F G + ++ L + E++ L+ GS D D+ L+++T Y
Sbjct: 62 YTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSP-DLDMHALQRSTQY 120
Query: 807 GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETD 866
G++++ +TI++FW V+ F + ++K L F P+ G LN F I T+
Sbjct: 121 DGYAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLN--FKISKNETSTN 178
Query: 867 RLPTASTCINLLKLPDYQNYHTLREKLLTAINSDSRFEL 905
LP A TC N L LP Y++ L++KL+ I++ F L
Sbjct: 179 CLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGL 217
>CE24948 [O] KOG0943 Predicted ubiquitin-protein ligase/hyperplastic discs
protein HECT superfamily
Length = 2944
Score = 88.6 bits (218), Expect = 4e-17
Identities = 81/293 (27%), Positives = 133/293 (44%), Gaps = 20/293 (6%)
Query: 617 KLFDTTSFNKLYPSK--NVSPQNLKYISFMGKILGKCLYENILVDVELADFFLKKILNVE 674
+LF+ + + Y K N +P L +G+I+G CL + + + + IL +
Sbjct: 2656 QLFEKAPYGEFYVPKIGNGAPMRLAAYRTVGRIMGICLSQGDIFPLRFSRHIFSYILKLP 2715
Query: 675 NNMNVPFNDLYSLDPEYYRNLMKLLEMSENELAYMDLYFEVPD-APNGKRIP--LIKDGL 731
+ + DL DP + NL L + +EL D F + + + +GK + L +G
Sbjct: 2716 ----ICWLDLGFYDPVLFNNLRALFKAHPSEL---DTDFSIVEQSADGKAVTVNLKPNGD 2768
Query: 732 STKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGS 791
V + NV EY+ + + L + G+ +IP L T +L+ +I G
Sbjct: 2769 EVLVNKDNVIEYVYKYAERVLVGKRIITFEAIREGILDVIPESMLFGLTPEDLRLIICGI 2828
Query: 792 EKDFDLEDLKKNTSYGGFSESSVTI-----QHFWQVLSSFTPEERRKFLKFVFSVPTAPL 846
E + L++NT + S +S Q FWQV+ SFT +E+++ + F P P
Sbjct: 2829 ES-VSISVLQENTGFLDESRASQETLNRFKQWFWQVIESFTQQEKQELVFFWTGSPALPA 2887
Query: 847 KGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAINS 899
G + +R D LPTA+TCI+ L +P Y + LR KLL AI +
Sbjct: 2888 AGKWPTSASVMLRPQEDVF--LPTANTCISRLYVPVYSSKRVLRTKLLLAIKA 2938
>YKL010c_2 [O] KOG0170 E3 ubiquitin protein ligase
Length = 470
Score = 88.6 bits (218), Expect = 4e-17
Identities = 72/276 (26%), Positives = 126/276 (45%), Gaps = 19/276 (6%)
Query: 638 LKYISFMGKILGKCLYENILVDVELADFFLKKI--LNVENNMNVPFND------LYSLDP 689
++ ++G + + L +N ++D + F + + ++ N VP + + +DP
Sbjct: 188 IELFGYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDP 247
Query: 690 EYYRNLMKLLEMSENELAY--MDLYFEVPDAPNGKRIPLIKDGLSTKVTQKNVFEYITRI 747
++L ++ ++ + + L F VP + I LI G + + NV EYI +
Sbjct: 248 LLAKSLKYIVANKDDNMTLESLSLTFTVPGNDD---IELIPGGCNKSLNSSNVEEYIHGV 304
Query: 748 SHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKN-TSY 806
L + FI G S + + + EL + E+D+ + L N +
Sbjct: 305 IDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYTNLNAE 364
Query: 807 GGFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGI--RNAGD- 863
G++ S I F ++S+F ERR FL+F+ P P+ GF SLNP F + ++A D
Sbjct: 365 HGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDG 424
Query: 864 --ETDRLPTASTCINLLKLPDYQNYHTLREKLLTAI 897
+ LP+ TC N LKLP Y + +R +L AI
Sbjct: 425 LTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAI 460
>CE17508 [R] KOG4276 Predicted hormone receptor interactor
Length = 2761
Score = 84.0 bits (206), Expect = 1e-15
Identities = 53/176 (30%), Positives = 88/176 (49%), Gaps = 3/176 (1%)
Query: 726 LIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELK 785
L+ G VT NV +Y+ + + LN + F G + P LR ++ E++
Sbjct: 2579 LVDGGSDIDVTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQ 2638
Query: 786 TLISGSE-KDFDLEDLKKNTSYG-GFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPT 843
L+SG + ++ +D+ T G++ S F V+ + T +ER+ FL+F +
Sbjct: 2639 RLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSS 2698
Query: 844 APLKGFHSLNP-LFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
P G +L+P L +R P+ +TC++ LKLP+Y + LRE+LLTAIN
Sbjct: 2699 LPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAIN 2754
>7297647 [R] KOG4276 Predicted hormone receptor interactor
Length = 2727
Score = 80.9 bits (198), Expect = 8e-15
Identities = 67/241 (27%), Positives = 113/241 (46%), Gaps = 10/241 (4%)
Query: 666 FLKKILNVE-NNMNVPFNDLYSLDPEYYR-NLMKL-----LEMSENELAYMDLYFEVPDA 718
FL+++ N+ ++ F+D S + ++ N +KL LE+S +LA Y
Sbjct: 2478 FLQEMQNLLLRKQSIEFDDTISAEKKHELINELKLQTQNGLEVSLEDLALTFTYLPSSSI 2537
Query: 719 PNGKRIPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRM 778
+ L+ +G S VT N+ Y + ++ L + F G + + P L
Sbjct: 2538 YGYTQAELLPNGSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAA 2597
Query: 779 FTSYELKTLISGSE-KDFDLEDLKKNTSYG-GFSESSVTIQHFWQVLSSFTPEERRKFLK 836
FT E + +I G + + ED+ T G+++ S Q F VL S + +ER+ FL+
Sbjct: 2598 FTPSEARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLLSMSGDERKAFLQ 2657
Query: 837 FVFSVPTAPLKGFHSLNP-LFGIRNAGDETDRLPTASTCINLLKLPDYQNYHTLREKLLT 895
F + P G +L+P L +R P+ +TC++ LKLPDY ++E+LLT
Sbjct: 2658 FTTGCSSLPPGGLANLHPRLTVVRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMKERLLT 2717
Query: 896 A 896
A
Sbjct: 2718 A 2718
>At4g38600 [O] KOG0170 E3 ubiquitin protein ligase
Length = 757
Score = 73.2 bits (178), Expect = 2e-12
Identities = 77/309 (24%), Positives = 127/309 (40%), Gaps = 52/309 (16%)
Query: 638 LKYISFMGKILGKCLYENILVDVELADFFLKKILNVENNMNVPFNDLYSLDPEYYRNLMK 697
++Y +G+++ K L + L+DV L+ F K IL E + +D+ D E + L +
Sbjct: 461 IEYFRLLGRVMAKALQDGRLLDVPLSTAFYKLILGQE----LDLHDIVLFDAELGKTLQE 516
Query: 698 L-----------------------LEMSENELAYMDLYFEVPDAPNGKRIPLIKDGLSTK 734
L L + + + L F +P P +++ G
Sbjct: 517 LRVVVARKHYLEGVGGDNSSTISDLCLRGCRIEDLSLEFTLPGYPE----YILRSG-DEI 571
Query: 735 VTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYELKTLISGSEKD 794
V N+ EYI+ + + + F +G + + L++FT EL L+ G +
Sbjct: 572 VDITNLEEYISLVVDATVKRGVTRQIEAFRSGFNQVFDITSLQIFTPSELDYLLCGRREL 631
Query: 795 FDLEDLKKNTSYG-GFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSVPTAPLKGFHSLN 853
+++E L ++ + G++ S I + SS +++R F +FV P P G LN
Sbjct: 632 WEVETLAEHIKFDHGYNAKSPAIINVCYPSSS---DQQRAFCQFVTGAPRLPPGGLAVLN 688
Query: 854 PLFGIRNAGDET---------------DRLPTASTCINLLKLPDYQNYHTLREKLLTAIN 898
P I T D LP+ TC N LKLP Y + +KLL AIN
Sbjct: 689 PKLTIVRKHSSTSSAAANGAGASETADDDLPSVMTCANYLKLPPYSTKEIMYKKLLYAIN 748
Query: 899 -SDSRFELS 906
F+LS
Sbjct: 749 EGQGSFDLS 757
>Hs15300020 [R] KOG4276 Predicted hormone receptor interactor
Length = 1592
Score = 72.8 bits (177), Expect = 2e-12
Identities = 47/176 (26%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Query: 724 IPLIKDGLSTKVTQKNVFEYITRISHYKLNLQLYTVTSRFITGLSYMIPAHWLRMFTSYE 783
+ L G +T N EY+ + + ++ + F G + + P L F+ E
Sbjct: 1408 VDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEE 1467
Query: 784 LKTLISGSEK-DFDLEDLKKNTSYG-GFSESSVTIQHFWQVLSSFTPEERRKFLKFVFSV 841
++ ++ G++ + ED+ T G++ S F +VL + +ER+ FL+F
Sbjct: 1468 VQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGC 1527
Query: 842 PTAPLKGFHSLNPLFGIRNAGDETDR-LPTASTCINLLKLPDYQNYHTLREKLLTA 896
T P G +L+P + D TD P+ +TC++ LKLP+Y + +RE+LL A
Sbjct: 1528 STLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAA 1583
>Hs13375805 [OK] KOG0939 E3 ubiquitin-protein ligase/Putative upstream
regulatory element binding protein
Length = 210
Score = 67.4 bits (163), Expect = 9e-11
Identities = 40/128 (31%), Positives = 68/128 (52%), Gaps = 6/128 (4%)
Query: 766 GLSYMIPAHWLRMFTSYELKTLISGSEKDFDLEDLKKNTSYGGFSESSVTIQHFWQVLSS 825
GL ++P L + T EL+ + G + + ++ L+K T + F S +Q+FW+ L++
Sbjct: 70 GLLKVVPQAVLDLLTWQELEKKVCG-DPEVTVDALRKLTRFEDFEPSDSRVQYFWEALNN 128
Query: 826 FTPEERRKFLKFVFSVPTAPLKGFHSLNPLFGIRNAGDETDRLPTASTCINLLKLPDYQN 885
FT E+R +FL+FV P + + ++ + + TD LP +STC + L LP Y +
Sbjct: 129 FTNEDRSRFLRFVTGRSRLPARIY-----IYPDKLGYETTDALPESSTCSSTLFLPHYAS 183
Query: 886 YHTLREKL 893
EKL
Sbjct: 184 AKVCEEKL 191
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.138 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,251,120
Number of Sequences: 60738
Number of extensions: 2234456
Number of successful extensions: 5803
Number of sequences better than 1.0e-05: 71
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 5469
Number of HSP's gapped (non-prelim): 95
length of query: 906
length of database: 30,389,216
effective HSP length: 116
effective length of query: 790
effective length of database: 23,343,608
effective search space: 18441450320
effective search space used: 18441450320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)