ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV3807 good MO KOG1771 Cell wall/membrane/envelope biogenesis GPI-alpha-mannosyltransferase III (GPI10/PIG-B) involved in glycosylphosphatidylinositol anchor biosynthesis
r_klactV3807 good MO KOG1771 Posttranslational modification, protein turnover, chaperones GPI-alpha-mannosyltransferase III (GPI10/PIG-B) involved in glycosylphosphatidylinositol anchor biosynthesis
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV3807 1319163 1320965 601
(601 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL142c [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PI... 650 0.0
SPCC16A11.06c [MO] KOG1771 GPI-alpha-mannosyltransferase III (GP... 213 9e-55
Hs20127468 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10... 204 2e-52
At5g14850 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/... 167 3e-41
7292390 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PI... 131 3e-30
Hs13376062 [MU] KOG2515 Mannosyltransferase 72 3e-12
7299245 [MU] KOG2516 Protein involved in dolichol pathway for N-... 59 2e-08
Hs13129114 [MU] KOG2516 Protein involved in dolichol pathway for... 59 3e-08
CE27213_1 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/... 59 3e-08
SPAC4G8.12c [G] KOG4123 Putative alpha 12 mannosyltransferase 54 9e-07
CE29152 [MU] KOG2516 Protein involved in dolichol pathway for N-... 54 9e-07
SPBC1734.12c [MU] KOG2516 Protein involved in dolichol pathway f... 52 3e-06
YOR149c [G] KOG4123 Putative alpha 12 mannosyltransferase 51 6e-06
>YGL142c [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B)
involved in glycosylphosphatidylinositol anchor
biosynthesis
Length = 616
Score = 650 bits (1677), Expect = 0.0
Identities = 308/599 (51%), Positives = 420/599 (69%), Gaps = 15/599 (2%)
Query: 9 RLFKVILVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWSFGLRSYAFPLIF 68
++F V L R + A+LTRTFFQADEFWQ+LEPAH+ AF YGELTWEW FG+RSY FP+IF
Sbjct: 16 QIFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPMIF 75
Query: 69 QIGYTLVKYAAISCE----LIVQTATDWVLLFVANVIPNSEFGWEMVQEMRSFPEEIRGF 124
++ Y LV ++I L+ +D ++L ++P E W++ ++++ P ++
Sbjct: 76 ELTYRLVSLSSILLHYALLLLSTIGSDLLIL----LLPKYELSWQVAEDLKRLPFDVTRS 131
Query: 125 IEYQGVIYAPKLIMAVLAAIGEFHVILLAEKLYKLTMXXXXXXXXXXXXX--XTVINFTL 182
EY GVIYAPK++MAVLA+IGE++++ +KLY LT+ + F L
Sbjct: 132 FEYYGVIYAPKIVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFAL 191
Query: 183 VATVSNFFNCFFITRSFINSFEMILTSVSLYYWDWTSGEHIESFDFLKSLIIGTFTVLQR 242
+ +++NFFNCFFITR+FINSFEMILTS++LYYWDWT G+ I+ F KSLI LQR
Sbjct: 192 LLSLTNFFNCFFITRTFINSFEMILTSIALYYWDWTGGQMIKESSFTKSLIFAFLACLQR 251
Query: 243 PTNAFIWLILGGYMILNLVLSKRWRKLFSLLIKVICASFISISTNLCIDYYFYGYITIPV 302
P++ IW+I +ILNLV K++ LF KV+ + F+ + N ID YFY +T P
Sbjct: 252 PSSGLIWVIPSISLILNLVGKKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPF 311
Query: 303 LKFIKFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLSPLVNP 362
+F+KFN T+ LSKFYGVAPW+FH FQSLPIV G S+P F L+K+ F +NP
Sbjct: 312 FRFLKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNP 371
Query: 363 FLQIKTVVLLNVILYSLIPHKEFRFIYPLQPFFIILSVFDGIWLLQKYGSTATTRTMEFF 422
F Q+K +LLN+++YS +PHKEFRFI+PLQP FI++S F + L + Y + +
Sbjct: 372 FFQVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLDRDY-----WKRLSGL 426
Query: 423 SQVMWILPVVSMVASMLLSTLHESGTVAVMDYLHSIRNIDSIGFIMPCHSTPWQSHFHRN 482
++W++P VS+ ++LL T HESG++ VM +LH IDS+GFIMPCHSTP QS+ HR+
Sbjct: 427 KSLLWLVPFVSVFIALLLDTFHESGSIEVMKFLHEEPEIDSLGFIMPCHSTPGQSYLHRS 486
Query: 483 DVKELWAITCSPPLHLLTDPDANAKLPFYMDESDYLYDNISKFMYQHFPPVFRKSLRSPG 542
D+++LW+ITC+PPLHLL DP+A +KL YMDESD+LYD+IS F+Y++FPP FRK LRSPG
Sbjct: 487 DIQDLWSITCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPG 546
Query: 543 KQYTYEWPEYLVIFEDLDSQFMNDYLVDSMYIEETRFFNSLVHWDKRRSGDIIIYHKMP 601
K Y++EWP YLV+FE +++ F+ D+L DS YIE RFFNSL HWD RRSGDIIIY+K+P
Sbjct: 547 KTYSHEWPTYLVVFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDSRRSGDIIIYYKLP 605
>SPCC16A11.06c [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B)
involved in glycosylphosphatidylinositol anchor
biosynthesis
Length = 506
Score = 213 bits (541), Expect = 9e-55
Identities = 172/621 (27%), Positives = 268/621 (42%), Gaps = 157/621 (25%)
Query: 14 ILVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWSFGLRSYAFPLIFQIGYT 73
ILV R AL +TFFQ DEF+QSLE AH+ F YG LTWEW+ +RS PLIF Y
Sbjct: 9 ILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPLIFAALYR 68
Query: 74 LVKYAAISCELIVQTATDWVLLFVANVIPNSEFGWEMVQEMRSFPEEIRGFIEYQGVIYA 133
+++ + V T A
Sbjct: 69 VLQVLKLDSSYFVFTN-------------------------------------------A 85
Query: 134 PKLIMAVLAAIGEFHVILLAEKLYKLTMXXXXXXXXXXXXXXTVINFTLVATVSNFFNCF 193
PKL+ AAI ++ A Y N+TL ++ + N +
Sbjct: 86 PKLLQGTFAAILDYGTYKFALVRY----------------GSKTANWTLACSLVSIMNAY 129
Query: 194 FITRSFINSFEMILTSVSLYYWDW-------TSGEHIESFDFLKSLI-IGTFTVLQRPTN 245
R+F NS E LTS+ YY+ + + + +++ L I + F RPTN
Sbjct: 130 VGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAFACFIRPTN 189
Query: 246 AFIWLI------------LGGYMILNLVLSKRWRKLFSLL------IKVICASFISISTN 287
+W+ + + + V + R+R L++L I V+C S + N
Sbjct: 190 ILVWIFPLLFWNKNPQTPIKDLLSFSNVFN-RFRFLYALGYGRLFGIFVLCVSLFLV--N 246
Query: 288 LCIDYYFYGYITIPVLKFIKFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFF 347
+ D YG P++ F +FN TS LS YG+ W++++ Q+LP++ G LP +
Sbjct: 247 IIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPFV----- 301
Query: 348 CSLTKKRFLSPLVNPFLQIKTVVLLNVILYSLIPHKEFRFIYPLQPFFIILSVFDGIWLL 407
L+ LQ +L YSLI HKE RF+YP+ P + L+
Sbjct: 302 -----------LLTMDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLA-------- 342
Query: 408 QKYGSTATT--RTMEFFSQVMWILPVVSMVASMLLSTLHESGTVAVMDYLHSIRNIDSIG 465
K+ S+ ++ R FF +++ + + L H+ G + VM +HS+ + G
Sbjct: 343 GKFFSSFSSWKRAARFF----FLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKNQTG 398
Query: 466 FIM-PCHSTPWQSHFHRNDVKELWA-ITCSPPLHLLTDPDANAKLPFYMDESDYLYDNIS 523
I+ PCH+TPWQSH H + W +TC P + PF DE+D Y+N+
Sbjct: 399 LILAPCHTTPWQSHIHSPFAENGWKFLTCEP-----------FEKPF--DETDRFYENM- 444
Query: 524 KFMYQHFPPVFRKSLRSPGKQYTYEWPEYLVIFEDLDSQFMNDY-LVDS---MYIEETRF 579
P F ++ EWP+YL+ FE+ +F + Y +DS Y E R+
Sbjct: 445 --------PTFLDKIK--------EWPDYLIFFEE---RFYSLYSYLDSRGLKYEEVQRY 485
Query: 580 FNSLVHWDKRRSGDIIIYHKM 600
+NSL+ + R+G +++Y K+
Sbjct: 486 YNSLIPESRERAGALLVYKKL 506
>Hs20127468 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B)
involved in glycosylphosphatidylinositol anchor
biosynthesis
Length = 554
Score = 204 bits (520), Expect = 2e-52
Identities = 155/592 (26%), Positives = 257/592 (43%), Gaps = 124/592 (20%)
Query: 15 LVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWSFGLRSYAFPLIFQIGYTL 74
L +R + L +T F DE+WQSLE +H+M F YG LTWEW+ LRSY +PLIF Y +
Sbjct: 68 LALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKI 127
Query: 75 VKYAAISCELIVQTATDWVLLFVANVIPNSEFGWEMVQEMRSFPEEIRGFIEYQGVIYAP 134
+ + G Q +I+ P
Sbjct: 128 L--------------------------------------------HLLGKDSVQLLIWIP 143
Query: 135 KLIMAVLAAIGEFHVILLAEKLYKLTMXXXXXXXXXXXXXXTVINFTLVATVSNFFNCFF 194
+L A+L+A+ + + L ++L V + + ++F +
Sbjct: 144 RLAQALLSAVADVRLYSLMKQLEN----------------QEVARWVFFCQLCSWFTWYC 187
Query: 195 ITRSFINSFEMILTSVSLYYWDWTSGEHIESFDFLKSLIIGTFTVLQRPTNAFIWLILGG 254
TR+ N+ E +LT ++L+Y+ + + S + SL+ F + RPT +W L
Sbjct: 188 CTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKY-SSLVALAFII--RPTAVILWTPL-- 242
Query: 255 YMILNLVLSKRWRKLFSLLIKVICASFISISTNLCIDYYFYGYITIPVLKFIKFNCTSSL 314
L + RKL +L + F+++S +L ID F+G T+ F+KFN +L
Sbjct: 243 ---LFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNL 299
Query: 315 SKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLSPLVNPFLQIKTVVLLNV 374
FYG PW+++ Q P++ G LP IH C L KR+ LV VL +
Sbjct: 300 GTFYGSHPWHWYFSQGFPVILGTHLPFFIHG--CYLAPKRYRILLV--------TVLWTL 349
Query: 375 ILYSLIPHKEFRFIYPLQPFFIILSVFDGIWLLQKYGSTATTRTMEFFSQVMWILPVVSM 434
++YS++ HKEFRFIYP+ PF ++ + + T + + L + ++
Sbjct: 350 LVYSMLSHKEFRFIYPVLPFCMVFCGY------------SLTHLKTWKKPALSFLFLSNL 397
Query: 435 VASMLLSTLHESGTVAVMDYLHSI------RNIDSIGFIMPCHSTPWQSHFHRNDVKELW 488
++ +H+ GT+ VM ++ + ++ SI +MPCHSTP+ SH H
Sbjct: 398 FLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVH-------- 449
Query: 489 AITCSPPLHLLTDPDANAKLPFYMDESDYLYDNISKFMYQHFPPVFRKSLRSPGKQYTYE 548
C P+ L P Y+DE+D Y N + ++ F
Sbjct: 450 ---CPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWSHREF-------------HDDAS 493
Query: 549 WPEYLVIFEDLDSQFMNDYLVDSMYIEETRFFNSLVHWDKRRSGD-IIIYHK 599
P +L+ F L+ + ++ +L+ S Y FF++ H + R G I +Y +
Sbjct: 494 LPTHLITFSILEEE-ISAFLISSNYKRTAVFFHT--HLPEGRIGSHIYVYER 542
>At5g14850 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B)
involved in glycosylphosphatidylinositol anchor
biosynthesis
Length = 498
Score = 167 bits (424), Expect = 3e-41
Identities = 135/504 (26%), Positives = 212/504 (41%), Gaps = 119/504 (23%)
Query: 8 KRLFKVILVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWSFGLRSYAFPLI 67
+R+F L R V ALL +T+F DE WQSLE AH FGYG +TWEW G+RSY P++
Sbjct: 39 RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPML 98
Query: 68 FQIGYTLVKYAAISCELIVQTATDWVLLFVANVIPNSEFGWEMVQEMRSFPEEIRGFIEY 127
F Y L++ + I+
Sbjct: 99 FAFLYKLLQVTGLDTPYIM----------------------------------------- 117
Query: 128 QGVIYAPKLIMAVLAAIGEFHVILLAEKLYKLTMXXXXXXXXXXXXXXTVINFTLVATVS 187
I AP+L+ ++ +AIG+ ++ L++ LY VAT S
Sbjct: 118 ---IKAPRLMQSIFSAIGDLYLYKLSDALYGGN----------------------VATWS 152
Query: 188 NFFNCFFITRSFINSFEMILTSVSLYYWDWTSGEHIESFDFLK-SLIIGTFTVLQRPTNA 246
+LT + LYYW I+ K L+I RPT+A
Sbjct: 153 T-----------------VLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSA 195
Query: 247 FIWLILGGYMILNLVLSKRWRKLFSLLIKVICASFISISTNLCIDYYFYGYITIPVLKFI 306
IWL +G +L L L+ K+ ++++VI + + +D YG I L F+
Sbjct: 196 VIWLYVG---MLELFLTPN--KVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFL 250
Query: 307 KFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLSPLVNPFLQI 366
KFN SS +YG PW+++ Q ++ P I S +K +
Sbjct: 251 KFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK------------L 298
Query: 367 KTVVLLNVILYSLIPHKEFRFIYPLQPFFIILS--VFDGIWLLQKYGSTATTRTMEFFSQ 424
++L + +YS++ HKEFRF+ P+ P +I S F + + S++ T+ + Q
Sbjct: 299 SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQ 358
Query: 425 -----------VMWILPVVSMVASMLLSTLHESGTVAVMDYLHSIR---NIDSIGFIMPC 470
++ L ++ ++ +S H+ GT M+YL + SI F+MPC
Sbjct: 359 NHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPC 418
Query: 471 HSTPWQSHFHRNDVKELWAITCSP 494
HSTP+ S HRN + + C+P
Sbjct: 419 HSTPYYSTLHRNIPMQF--LDCTP 440
>7292390 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B)
involved in glycosylphosphatidylinositol anchor
biosynthesis
Length = 512
Score = 131 bits (329), Expect = 3e-30
Identities = 116/466 (24%), Positives = 204/466 (42%), Gaps = 72/466 (15%)
Query: 151 LLAEKLYKLTMXXXXXXXXXXXXXXTVINFTLVATVSNFFNCFFITRSFINSFEMILTSV 210
LL LYK+ + + L + +F + +R+ N+ E LT++
Sbjct: 62 LLIAGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANTLEASLTTI 121
Query: 211 SLYYWDWTSGEHIESFDFLKSLIIGTFTVLQRPTNAFIWLILGGYMILNLVLSKRWRKLF 270
+L Y+ W ES +L I F RPT A IWL L Y + R L
Sbjct: 122 ALSYFPWYG----ESTAYLWPAAICCFL---RPTAAVIWLPLSLYHLRR----SRQNVLE 170
Query: 271 SLLIKVICASFISISTNLCIDYYFYGYITIPVLKFIKFNCTSSLSKFYGVAPWNFHVFQS 330
+L + + + + ID Y++G + + +F+K+N +++ FYG PW+++
Sbjct: 171 LILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVG 230
Query: 331 LPIVAGY-SLPLLIHSFFCSLTKKRFLSPLVNPFLQIKTVVLLNVILYSLIPHKEFRFIY 389
LP V G +LP + KK P+ Q+ + L +++ S + HKEFRF+
Sbjct: 231 LPTVLGINTLPFIFG--VMETVKKSEKYPVSK---QLLITIFLTLVVLSAVEHKEFRFVS 285
Query: 390 PLQPFFIILSVFDGIWLLQKYGSTATTRTMEFFSQVMWILPVVSMVASML----LSTLHE 445
PL P + + + D L ++ A+ S ++W +V +V +++ LST+H+
Sbjct: 286 PLLPLCLYV-ITDA---LSRWSIRAS-------STMLWTTALVILVGNVMPAWYLSTVHQ 334
Query: 446 SGTVAVMDYLHSI--------RNIDSIGFIMPCHSTPWQSHFHRNDVKELWAITCSPPLH 497
G + +M L I + +I F+MPCHSTP+ SH H+N +TC P L
Sbjct: 335 KGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRF--LTCEPNLE 392
Query: 498 LLTDPDANAKLPFYMDESDYLYDNISKFMYQHFPPVFRKSLRSPGKQYTYEWPEYLVIFE 557
K Y DE+D +++ ++ H P +L P ++V+F+
Sbjct: 393 ---------KKEQYKDEADRFFEDPVHWINSHIPMHPLTAL-----------PTHVVLFD 432
Query: 558 DLDSQFMNDYLVDSMYIEETRFFNSLVHWDKRRS---GDIIIYHKM 600
L S+++ R + + H + R+S I++Y ++
Sbjct: 433 PLAENI-------SVFLRNYRLLHRIEHAENRQSRTGRSILVYQRL 471
Score = 73.2 bits (178), Expect = 1e-12
Identities = 29/58 (50%), Positives = 41/58 (70%)
Query: 10 LFKVILVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWSFGLRSYAFPLI 67
+F +IL +R + +T++ DE+WQSLE AH + FGYG LTWEW G+RSY +PL+
Sbjct: 6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLL 63
>Hs13376062 [MU] KOG2515 Mannosyltransferase
Length = 618
Score = 71.6 bits (174), Expect = 3e-12
Identities = 87/397 (21%), Positives = 159/397 (39%), Gaps = 87/397 (21%)
Query: 11 FKVILVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWS--FGLRSYAFPLIF 68
FK +L R ALL+ DE + EP HY+ +G G TWE+S + +RSYA+ L+
Sbjct: 62 FKCLLSARLCAALLSN-ISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 69 QIGYTLVKYAAISCELIVQTATDWVLLFVANVIPNSEFGWEMVQEMRSFPEEIRGFIEYQ 128
W F A ++ ++
Sbjct: 121 A----------------------WPAAFHARILQTNKIL--------------------- 137
Query: 129 GVIYAPKLIMAVLAAIGEFHVILLAEKLYKLTMXXXXXXXXXXXXXXTVINFTLVATVSN 188
V Y + ++A ++ I E + K + L + ++ F +++T
Sbjct: 138 -VFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRM------------MLAFLVLST--- 181
Query: 189 FFNCFFITRSFI-NSFEMILTSVSL--YYWDWTSGEHIESFDFLKSLIIGTFTVLQRPTN 245
F + +F+ +SF M T +++ +Y D TS + L + +L P +
Sbjct: 182 --GMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTS---------IAVLGVAAGAILGWPFS 230
Query: 246 AFIWLILGGYMILNLVLSKRWRKLFSLLIKVICASFISISTNLCIDYYFYGYITIPVLKF 305
A + L + + LV+ RW+ F + + + + + ID Y+YG + I L
Sbjct: 231 AALGLPIAFDL---LVMKHRWKSFFHWSLMALILFLVPV---VVIDSYYYGKLVIAPLNI 284
Query: 306 IKFNC-TSSLSKFYGVAPWNFHVFQS-LPIVAGYSLPLLI---HSFFCSLTKKRFLSPLV 360
+ +N T YG PW F++ L ++L LL+ S L ++ + L
Sbjct: 285 VLYNIFTPHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLG 344
Query: 361 NPFLQIKTVVLLNVILYSLIPHKEFRFIYPLQPFFII 397
+P+ + + I++ + PHKE RF++P+ P +
Sbjct: 345 HPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL 381
>7299245 [MU] KOG2516 Protein involved in dolichol pathway for
N-glycosylation (mannosyltransferase family)
Length = 678
Score = 58.9 bits (141), Expect = 2e-08
Identities = 53/214 (24%), Positives = 100/214 (45%), Gaps = 24/214 (11%)
Query: 180 FTLVATVSNFFNCFFITRSFINSFEMILTSVSLYYWDWTSGEHIESFDFLKSLIIGTFTV 239
FT + T++ F F++TR N F + + ++ YW +H + F + I F
Sbjct: 118 FTAI-TITQFHFMFYMTRPLPNIFALPIVLFAIAYW--LRDQH-KPFIICSGISILVF-- 171
Query: 240 LQRPTNAFIWLILGGYMILNLVLSKRWRKLFSLLIKVICASFISISTNLCIDYYFYGYIT 299
+ + L LG ++++L+ +R + LL + A ++ + +D +F+ +
Sbjct: 172 -----RSELALFLGILLVVSLL--RRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLL 224
Query: 300 IPVLKFIKFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLSPL 359
P + + +N + S +G +P+ ++ + +LP G SL L+ L P
Sbjct: 225 WPEGEVLWYNTVLNKSSNWGTSPFLWYFYSALPRAMGASLVLVPIGVA--------LEPR 276
Query: 360 VNPFLQIKTVVLLNVILYSLIPHKEFRFIYPLQP 393
+ P + LL V+LYS++PHKE RFI + P
Sbjct: 277 IRPLV---LSALLFVLLYSILPHKELRFIIYVFP 307
>Hs13129114 [MU] KOG2516 Protein involved in dolichol pathway for
N-glycosylation (mannosyltransferase family)
Length = 488
Score = 58.5 bits (140), Expect = 3e-08
Identities = 59/229 (25%), Positives = 96/229 (41%), Gaps = 30/229 (13%)
Query: 185 TVSNFFNCFFITRSFINSFEMILTSVSLYYW---DWTSGEHIESFDFLKSLIIGTFTVLQ 241
T F F+ TR+ N + + ++L W +W F +L + I F V
Sbjct: 134 TAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWAR------FIWLSAFAIIVFRVE- 186
Query: 242 RPTNAFIWLILGGYMILNLVLSKRWRKLFSLLIKVICASFISISTNLCIDYYFYGYITIP 301
+ L LG ++L L L R + L + A + + + +D YF+ +T P
Sbjct: 187 ------LCLFLG--LLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWP 238
Query: 302 VLKFIKFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLSPLVN 361
K + +N + S +G +P ++ + +LP G SL + L +R +P V
Sbjct: 239 EGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIP----LGLVDRRTHAPTV- 293
Query: 362 PFLQIKTVVLLNVILYSLIPHKEFRFIYPLQPFFIILSVFDGIWLLQKY 410
+ L + LYSL+PHKE RFI P I + +LL Y
Sbjct: 294 -------LALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNY 335
>CE27213_1 [MO] KOG1771 GPI-alpha-mannosyltransferase III (GPI10/PIG-B)
involved in glycosylphosphatidylinositol anchor
biosynthesis
Length = 183
Score = 58.5 bits (140), Expect = 3e-08
Identities = 24/59 (40%), Positives = 36/59 (60%)
Query: 9 RLFKVILVIRCVQALLTRTFFQADEFWQSLEPAHYMAFGYGELTWEWSFGLRSYAFPLI 67
RL ++V RC+ L ++F DE +QS E AH++ +G G L+WEW LRS+ P +
Sbjct: 6 RLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPAL 64
>SPAC4G8.12c [G] KOG4123 Putative alpha 12 mannosyltransferase
Length = 533
Score = 53.5 bits (127), Expect = 9e-07
Identities = 51/219 (23%), Positives = 94/219 (42%), Gaps = 21/219 (9%)
Query: 187 SNFFNCFFITRSFINSFEMILTSVSLYYWDWTSGEHI-ESFDFLKSLIIGTFTVLQRPTN 245
S+F F T +F NS E I +++ + + + + +L + ++ +VL T
Sbjct: 128 SSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVLGFFTR 187
Query: 246 -AFIWLILGGYMILNLVLSKRW----RKLFSLLIKVICASFISISTNLCIDYYFYGYITI 300
F+ ++ Y+ ++ K+ + +F L + SF ++ + DY FYG I
Sbjct: 188 ITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYKFYGVFVI 247
Query: 301 PVLKFIKFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLSPLV 360
+K+N +G+ H F ++P++ G PL+ F+ L
Sbjct: 248 TFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCG---PLI------------FVPKLW 292
Query: 361 NPFLQIKTVVLLNVILYSLIPHKEFRFIYPLQPFFIILS 399
+ + LL V + SL PH+E RF+ P FI+ S
Sbjct: 293 DVRKPATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNS 331
>CE29152 [MU] KOG2516 Protein involved in dolichol pathway for
N-glycosylation (mannosyltransferase family)
Length = 492
Score = 53.5 bits (127), Expect = 9e-07
Identities = 92/400 (23%), Positives = 155/400 (38%), Gaps = 82/400 (20%)
Query: 187 SNFFNCFFITRSFINSFEMILTSVSLYYWDWTSGEHIESFDFLKSLIIGTFTVLQRPTNA 246
+ F F+++R N+F +IL + + L+ G + R A
Sbjct: 128 TQFHYIFYMSRPLPNTFALILVMI-----------------VFERLLEGRYESAVRYATA 170
Query: 247 FIWL------ILGGYMILNLVLSKRWRKLF----SLLIKVICASFISISTNLCIDYYFYG 296
+ L +L G + L ++S R K+F ++ I V A+ + ++ ++ ID YF+G
Sbjct: 171 SVILFRCELVLLYGPIFLGYMISGRL-KVFGFDGAIAIGVRIAA-MCLAVSIPIDSYFWG 228
Query: 297 YITIPVLKFIKFNCTSSLSKFYGVAPWNFHVFQSLP---IVAGYSLPLLIHSFFCSLTKK 353
P + + FN + S YG P+ ++ + +LP + +PL L
Sbjct: 229 RPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPL-------GLLVD 281
Query: 354 RFLSPLVNPFLQIKTVVLLNVILYSLIPHKEFRF-IYPLQPFFIILSVFDGIWLLQKYGS 412
R L +V P + + + LYS +PHKE RF IY L F + +VF L+ ++ S
Sbjct: 282 RRLPQIVLPSV-------IFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKS 334
Query: 413 TATTRTMEFFSQVMWILPVVSMVASMLLSTLHESGTVAVMDYLHSIRNID-----SIGFI 467
R + FF ++ +L V LL ++YL D ++
Sbjct: 335 --FFRMILFFGVILHLLANVLCTGMFLLVASKNYPGFDALNYLQFQNRFDAKKPVTVYID 392
Query: 468 MPCHSTPWQSHFHRNDVKELWAITCSPPLHLLTDPDANAKLPFYMDESDYL----YDNI- 522
C T H ND W + L P ++ D+L Y N
Sbjct: 393 NACAQTGVNRFLHINDA---WTYNKTENLK-----------PADLENFDFLVLGTYGNTL 438
Query: 523 -----SKFMYQHFPPVFRKSLR----SPGKQYTYEWPEYL 553
SKF+ H P F S +Q+ + +PE +
Sbjct: 439 KTEVESKFVTWHRPLFFVNSFHQYKIKKSRQFPWIYPEII 478
>SPBC1734.12c [MU] KOG2516 Protein involved in dolichol pathway for
N-glycosylation (mannosyltransferase family)
Length = 547
Score = 51.6 bits (122), Expect = 3e-06
Identities = 72/302 (23%), Positives = 122/302 (39%), Gaps = 48/302 (15%)
Query: 111 VQEMRSFPEEIRGFIEYQGVI---YAPKLIMAVLAAIGEFHVILLAEKLYKLTMXXXXXX 167
+Q R ++ +E+ G + + P L +AVL+ I + V L + +
Sbjct: 44 IQTYRWDLSKVYDHLEFPGAVKRSFIPSLFIAVLSYIPSWFVNPLLAARWTIGYLSWESM 103
Query: 168 XXXXXXXXTVINFTLVATVSNFFNC------FFITRSFINSFEMILTSVSLYYWDWTSGE 221
TL + F+C ++++R N F +I T+ SL
Sbjct: 104 NSVSCSISKRFG-TLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSL------- 155
Query: 222 HIESFDFLKSLIIGTFTVLQ------RPTNAFIWLILGGYMILNLVLSKRWRKLFSLLIK 275
LK+ G+ ++L R A + + L IL L+L +R L LL+
Sbjct: 156 ------LLKNNYYGSISILVFAAAIVRSEIALLLMCL----ILPLLLQRRIT-LSKLLLV 204
Query: 276 VICASFISISTNLCIDYYFYGYITIPVLKFIKFNCTSSLSKFYGVAPWNFHVFQSLP--I 333
I +S ++ + ID YF+G P L+ FN S +G +P+ ++ F LP
Sbjct: 205 GISSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPF-YYYFVRLPWLF 263
Query: 334 VAGYSLPLLIHSFFCSLTKKRFLSPLVNPFLQIKTVVLLNVILYSLIPHKEFRFIYPLQP 393
+ +L L+ SF + P + V L + +YS + HKE+RFI P
Sbjct: 264 LNPTTLLFLLISFV-----------YIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSIP 312
Query: 394 FF 395
+F
Sbjct: 313 WF 314
>YOR149c [G] KOG4123 Putative alpha 12 mannosyltransferase
Length = 516
Score = 50.8 bits (120), Expect = 6e-06
Identities = 65/244 (26%), Positives = 108/244 (43%), Gaps = 42/244 (17%)
Query: 186 VSNFFNCFFITRSFINSFEMI-LTSVSLYYWDWTSGEHIESFDFLKSLIIG---TFTVLQ 241
++++ + T +F NS E + L S D + ++I+ +F S+I+G +F V
Sbjct: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
Query: 242 RPT-NAFIWLILGGYMILNLVLSKRWRKLFSLLIKVICAS---FISISTNLCIDYYFYGY 297
R T AFI+L +IL + K FSLL+ S F+ I TN+ + G+
Sbjct: 188 RVTFPAFIFLPC---LILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK--GF 242
Query: 298 ITIPVLKFIKFNCTSSLSKFYGVAPWNFHVFQSLPIVAGYSLPLLIHSFFCSLTKKRFLS 357
+ P L +K+N + +G+ P H+ +LP + G L L I S + L K
Sbjct: 243 VITP-LNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY-KLDK----- 295
Query: 358 PLVNPFLQIKTVVLLNVILY-SLIPHKEFRFIYPLQPFFII-------------LSVFDG 403
+ T +++ +L+ S H+E RF+ PL P + +F G
Sbjct: 296 --------LSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKG 347
Query: 404 IWLL 407
WLL
Sbjct: 348 TWLL 351
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.329 0.142 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,011,645
Number of Sequences: 60738
Number of extensions: 1486308
Number of successful extensions: 4029
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3983
Number of HSP's gapped (non-prelim): 20
length of query: 601
length of database: 30,389,216
effective HSP length: 112
effective length of query: 489
effective length of database: 23,586,560
effective search space: 11533827840
effective search space used: 11533827840
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)